FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0491, 365 aa 1>>>pF1KA0491 365 - 365 aa - 365 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0442+/-0.00106; mu= 7.8306+/- 0.064 mean_var=100.8382+/-20.198, 0's: 0 Z-trim(105.0): 70 B-trim: 32 in 1/50 Lambda= 0.127721 statistics sampled from 8153 (8208) to 8153 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.252), width: 16 Scan time: 2.160 The best scores are: opt bits E(32554) CCDS710.1 SH3GLB1 gene_id:51100|Hs108|chr1 ( 365) 2333 440.6 9.9e-124 CCDS55613.1 SH3GLB1 gene_id:51100|Hs108|chr1 ( 265) 1691 322.3 3e-88 CCDS55612.1 SH3GLB1 gene_id:51100|Hs108|chr1 ( 386) 1212 234.1 1.6e-61 CCDS72819.1 SH3GLB1 gene_id:51100|Hs108|chr1 ( 394) 1212 234.1 1.6e-61 CCDS69680.1 SH3GLB2 gene_id:56904|Hs108|chr9 ( 404) 897 176.0 4.9e-44 CCDS6916.1 SH3GLB2 gene_id:56904|Hs108|chr9 ( 395) 896 175.9 5.4e-44 CCDS32874.1 SH3GL1 gene_id:6455|Hs108|chr19 ( 368) 422 88.5 1e-17 CCDS6483.1 SH3GL2 gene_id:6456|Hs108|chr9 ( 352) 312 68.2 1.2e-11 CCDS10325.2 SH3GL3 gene_id:6457|Hs108|chr15 ( 347) 306 67.1 2.6e-11 CCDS73772.1 SH3GL3 gene_id:6457|Hs108|chr15 ( 355) 300 66.0 5.6e-11 >>CCDS710.1 SH3GLB1 gene_id:51100|Hs108|chr1 (365 aa) initn: 2333 init1: 2333 opt: 2333 Z-score: 2334.8 bits: 440.6 E(32554): 9.9e-124 Smith-Waterman score: 2333; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 KAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 KAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 CYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 CYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 LKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 LKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITY 310 320 330 340 350 360 pF1KA0 LELLN ::::: CCDS71 LELLN >>CCDS55613.1 SH3GLB1 gene_id:51100|Hs108|chr1 (265 aa) initn: 1691 init1: 1691 opt: 1691 Z-score: 1697.8 bits: 322.3 E(32554): 3e-88 Smith-Waterman score: 1691; 100.0% identity (100.0% similar) in 265 aa overlap (101-365:1-265) 80 90 100 110 120 130 pF1KA0 PNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGT :::::::::::::::::::::::::::::: CCDS55 MIDAGTEFGPGTAYGNALIKCGETQKRIGT 10 20 30 140 150 160 170 180 190 pF1KA0 ADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KA0 SEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQK 100 110 120 130 140 150 260 270 280 290 300 310 pF1KA0 QLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKA 160 170 180 190 200 210 320 330 340 350 360 pF1KA0 RVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN 220 230 240 250 260 >>CCDS55612.1 SH3GLB1 gene_id:51100|Hs108|chr1 (386 aa) initn: 1212 init1: 1212 opt: 1212 Z-score: 1218.1 bits: 234.1 E(32554): 1.6e-61 Smith-Waterman score: 2281; 94.6% identity (94.6% similar) in 386 aa overlap (1-365:1-386) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 130 140 150 160 170 180 190 200 210 pF1KA0 KAKAAETRNS---------------------SEQELRITQSEFDRQAEITRLLLEGISST :::::::::: ::::::::::::::::::::::::::::: CCDS55 KAKAAETRNSQLNSARLEGDNIMIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISST 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 HAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAI 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 GSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVG 310 320 330 340 350 360 340 350 360 pF1KA0 MDSDWLMGERGNQKGKVPITYLELLN :::::::::::::::::::::::::: CCDS55 MDSDWLMGERGNQKGKVPITYLELLN 370 380 >>CCDS72819.1 SH3GLB1 gene_id:51100|Hs108|chr1 (394 aa) initn: 1212 init1: 1212 opt: 1212 Z-score: 1218.0 bits: 234.1 E(32554): 1.6e-61 Smith-Waterman score: 2265; 92.6% identity (92.6% similar) in 394 aa overlap (1-365:1-394) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 130 140 150 160 170 180 190 200 210 pF1KA0 KAKAAETRNS-----------------------------SEQELRITQSEFDRQAEITRL :::::::::: ::::::::::::::::::::: CCDS72 KAKAAETRNSQLNSARLEGDNIMVNFSYMLNFLHVKWLKSEQELRITQSEFDRQAEITRL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 LLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 LLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPV 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 PSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 PSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEV 310 320 330 340 350 360 340 350 360 pF1KA0 ITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN :::::::::::::::::::::::::::::::::: CCDS72 ITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN 370 380 390 >>CCDS69680.1 SH3GLB2 gene_id:56904|Hs108|chr9 (404 aa) initn: 1552 init1: 897 opt: 897 Z-score: 904.1 bits: 176.0 E(32554): 4.9e-44 Smith-Waterman score: 1437; 58.5% identity (81.8% similar) in 395 aa overlap (4-355:1-394) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM ::::.::::.::: :..:::::::::.:::::::::::.::::..:. :: :::::. CCDS69 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKIL 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK .::::::::::.::.:::.:::::::.:::..: :::.::: ::..:.:: : ::..::: CCDS69 RQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK .:..:..:.:.:..:.:....::::::::.:::.:::.:::.::::.:::::: :.::: CCDS69 VAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLK 120 130 140 150 160 170 190 200 pF1KA0 KAKAAETR---------------------------------NSSEQELRITQSEFDRQAE ::::::.. ...:::::..:.::::::: CCDS69 KAKAAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAE 180 190 200 210 220 230 210 220 230 240 250 260 pF1KA0 ITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGS-----FPSNYLSN .::::::::::::..:::::..::..: :::::::..:::::::::: ::...... CCDS69 VTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGT 240 250 260 270 280 290 270 280 290 300 310 pF1KA0 NNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSD-LKEC----SGSRKARVLYDYD .. .: :. :. :.. ... . : .. :.. : :.: ::.:::::::::. CCDS69 TEPAS-PPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYE 300 310 320 330 340 350 320 330 340 350 360 pF1KA0 AANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN ::.:.::.:::::.:::.:. ::: :::.:::::.::: CCDS69 AADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS 360 370 380 390 400 >>CCDS6916.1 SH3GLB2 gene_id:56904|Hs108|chr9 (395 aa) initn: 1563 init1: 896 opt: 896 Z-score: 903.3 bits: 175.9 E(32554): 5.4e-44 Smith-Waterman score: 1513; 60.1% identity (83.6% similar) in 396 aa overlap (4-365:1-395) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM ::::.::::.::: :..:::::::::.:::::::::::.::::..:. :: :::::. CCDS69 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKIL 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK .::::::::::.::.:::.:::::::.:::..: :::.::: ::..:.:: : ::..::: CCDS69 RQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK .:..:..:.:.:..:.:....::::::::.:::.:::.:::.::::.:::::: :.::: CCDS69 VAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLK 120 130 140 150 160 170 190 200 210 pF1KA0 KAKAAETRNSS-----------------------------EQELRITQSEFDRQAEITRL ::::::.. .. :::::..:.:::::::.::: CCDS69 KAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRL 180 190 200 210 220 230 220 230 240 250 260 270 pF1KA0 LLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPV :::::::::..:::::..::..: :::::::..::::::::: ::........ .: :. CCDS69 LLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPAS-PPL 240 250 260 270 280 290 280 290 300 310 320 pF1KA0 PSVLPNAIGSSAMASTSGLVITSPSNLSD-LKEC----SGSRKARVLYDYDAANSTELSL :. :.. ... . : .. :.. : :.: ::.:::::::::.::.:.::.: CCDS69 SSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADSSELAL 300 310 320 330 340 350 330 340 350 360 pF1KA0 LADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN ::::.:::.:. ::: :::.:::::.:::::.::::::. CCDS69 LADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS 360 370 380 390 >>CCDS32874.1 SH3GL1 gene_id:6455|Hs108|chr19 (368 aa) initn: 335 init1: 193 opt: 422 Z-score: 431.7 bits: 88.5 E(32554): 1e-17 Smith-Waterman score: 432; 27.3% identity (57.9% similar) in 366 aa overlap (21-364:12-363) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM .: :.. ::.: :: :.:: .... .:.. :. . ... CCDS32 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVL 10 20 30 40 50 70 80 90 100 110 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDR-----KAPSRINNPELLGQYMIDAGTEFGPGTAYG .: ::::: .: . . . ... : :. .. :::. :: : :.: . .: CCDS32 ARTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 NALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAA .::. ::..::.. . : ::. ::.:. : : : : .. : :...:::.: CCDS32 DALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 KTRLKKAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQM : : : ..::: . .:... :... .... : ... :. .:.::. CCDS32 KKRQGKIP--------DEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQL 180 190 200 210 220 240 250 260 270 pF1KA0 TYYAQCYQYMLDLQKQL-------GSFPS-NY---------LSNNNQTSVTPVPSVLPNA :. : : . .: ..: .: :. .: :.. .:.. .. :. CCDS32 DYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKI 230 240 250 260 270 280 280 290 300 310 320 330 pF1KA0 IGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVV .::.. :.. . : .. : . : ..:::.. :. ::.. .:::. . . CCDS32 AASSSFRSSDKPIRTPSRSMPPLDQPS----CKALYDFEPENDGELGFHEGDVITLTNQI 290 300 310 320 330 340 350 360 pF1KA0 GMDSDWLMGERGNQKGKVPITYLELLN : .: : .:.: :..:.:.: CCDS32 --DENWYEGMLDGQSGFFPLSYVEVLVPLPQ 340 350 360 >>CCDS6483.1 SH3GL2 gene_id:6456|Hs108|chr9 (352 aa) initn: 365 init1: 154 opt: 312 Z-score: 322.5 bits: 68.2 E(32554): 1.2e-11 Smith-Waterman score: 397; 26.1% identity (56.5% similar) in 352 aa overlap (21-364:12-347) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM .:.: . ::.: :: :.:: .... :.. :. . .:: CCDS64 MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIM 10 20 30 40 50 70 80 90 100 110 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDR-----KAPSRINNPELLGQYMIDAGTEFGPGTAYG .: ::::: .: . . . ... :.:. . ::.. :. : :.: .: CCDS64 TKTIEYLQPNPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 NALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAA :: . ::...... . : ::. ::.:. . : . : .. : :...:::.: CCDS64 PALGEVGEAMRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 KTRLKKAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQM : : : ..::: . .::.. ::.. . .. ... :. .:.::. CCDS64 KKRQGKIP--------DEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQL 180 190 200 210 220 240 250 260 270 280 290 pF1KA0 TYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSV---LPNAIGSSAMASTSGLVI :. : : . .. .: . :.. . : : . .:.. ... .. : CCDS64 EYHKQAVQILQQVTVRLEERIRQA-SSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGT 230 240 250 260 270 280 300 310 320 330 340 350 pF1KA0 TSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQ .::... . : :.:::.. : ::.. ..::. . . : .: : .. CCDS64 PKPSGVQMDQPCC-----RALYDFEPENEGELGFKEGDIITLTNQI--DENWYEGMLHGH 290 300 310 320 330 360 pF1KA0 KGKVPITYLELLN .: ::.:.:.: CCDS64 SGFFPINYVEILVALPH 340 350 >>CCDS10325.2 SH3GL3 gene_id:6457|Hs108|chr15 (347 aa) initn: 297 init1: 173 opt: 306 Z-score: 316.6 bits: 67.1 E(32554): 2.6e-11 Smith-Waterman score: 394; 26.9% identity (57.5% similar) in 353 aa overlap (21-364:12-342) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM .: :. ::.. :: :.:: .. .. : . :. . .:. CCDS10 MSVAGLKKQFHKASQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEIL 10 20 30 40 50 70 80 90 100 110 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDR-----KAPSRINNPELLGQYMIDAGTEFGPGTAYG ..: ::::: : . . . ... :. . .. :::. :. : :.: ...: CCDS10 SKTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 NALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAA ::::. ::..: .. . : . .:. ::. . . : : :... : :...::: : CCDS10 NALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 KTRLKKAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQM : :. : :.:.. :. :... :... . .. . .... : :.:: . CCDS10 KKRVGKIPDEEVRQAVEK--------FEESKELAERSMFNFLENDVEQVSQLAVFIEAAL 180 190 200 210 220 240 250 260 270 280 290 pF1KA0 TYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAI--GSSAM--ASTSGLV :. : . . .::..: . . .:: : : . .:: . .::...: CCDS10 DYHRQSTEILQELQSKL------QMRISAASSV-PRREYKPRPVKRSSSELNGVSTTSVV 230 240 250 260 270 300 310 320 330 340 350 pF1KA0 ITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGN :. ::. . : : :::.. :. ::.. ..::. . . : .: : . CCDS10 KTTGSNIPMDQPCC-----RGLYDFEPENQGELGFKEGDIITLTNQI--DENWYEGMIHG 280 290 300 310 320 360 pF1KA0 QKGKVPITYLELLN ..: ::.:.:.. CCDS10 ESGFFPINYVEVIVPLPQ 330 340 >>CCDS73772.1 SH3GL3 gene_id:6457|Hs108|chr15 (355 aa) initn: 297 init1: 173 opt: 300 Z-score: 310.5 bits: 66.0 E(32554): 5.6e-11 Smith-Waterman score: 388; 26.9% identity (57.4% similar) in 350 aa overlap (24-364:23-350) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM :. ::.. :: :.:: .. .. : . :. . .:. CCDS73 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEIL 10 20 30 40 50 70 80 90 100 110 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDR-----KAPSRINNPELLGQYMIDAGTEFGPGTAYG ..: ::::: : . . . ... :. . .. :::. :. : :.: ...: CCDS73 SKTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 NALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAA ::::. ::..: .. . : . .:. ::. . . : : :... : :...::: : CCDS73 NALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 KTRLKKAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQM : :. : :.:.. :. :... :... . .. . .... : :.:: . CCDS73 KKRVGKIPDEEVRQAVEK--------FEESKELAERSMFNFLENDVEQVSQLAVFIEAAL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 TYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAI--GSSAM--ASTSGLV :. : . . .::..: . . .:: : : . .:: . .::...: CCDS73 DYHRQSTEILQELQSKL------QMRISAASSV-PRREYKPRPVKRSSSELNGVSTTSVV 240 250 260 270 280 300 310 320 330 340 350 pF1KA0 ITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGN :. ::. . : : :::.. :. ::.. ..::. . . : .: : . CCDS73 KTTGSNIPMDQPCC-----RGLYDFEPENQGELGFKEGDIITLTNQI--DENWYEGMIHG 290 300 310 320 330 360 pF1KA0 QKGKVPITYLELLN ..: ::.:.:.. CCDS73 ESGFFPINYVEVIVPLPQ 340 350 365 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:08:57 2016 done: Wed Nov 2 19:08:58 2016 Total Scan time: 2.160 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]