FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0491, 365 aa 1>>>pF1KA0491 365 - 365 aa - 365 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4511+/-0.000449; mu= 11.7121+/- 0.028 mean_var=122.2866+/-25.632, 0's: 0 Z-trim(112.4): 150 B-trim: 965 in 2/55 Lambda= 0.115980 statistics sampled from 21108 (21267) to 21108 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.249), width: 16 Scan time: 8.030 The best scores are: opt bits E(85289) NP_057093 (OMIM: 609287) endophilin-B1 isoform 1 [ ( 365) 2333 401.9 1.2e-111 NP_001193582 (OMIM: 609287) endophilin-B1 isoform ( 265) 1691 294.4 2e-79 XP_005252157 (OMIM: 609288) PREDICTED: endophilin- ( 379) 1230 217.4 4.4e-56 XP_011539840 (OMIM: 609287) PREDICTED: endophilin- ( 378) 1220 215.7 1.4e-55 XP_016856899 (OMIM: 609287) PREDICTED: endophilin- ( 219) 1214 214.5 1.9e-55 XP_016856898 (OMIM: 609287) PREDICTED: endophilin- ( 235) 1212 214.2 2.5e-55 NP_001193581 (OMIM: 609287) endophilin-B1 isoform ( 386) 1212 214.3 3.6e-55 NP_001193580 (OMIM: 609287) endophilin-B1 isoform ( 394) 1212 214.4 3.6e-55 XP_006710735 (OMIM: 609287) PREDICTED: endophilin- ( 402) 1212 214.4 3.7e-55 XP_016856897 (OMIM: 609287) PREDICTED: endophilin- ( 286) 1138 201.9 1.5e-51 XP_006710736 (OMIM: 609287) PREDICTED: endophilin- ( 302) 1131 200.7 3.6e-51 XP_006717254 (OMIM: 609288) PREDICTED: endophilin- ( 399) 897 161.7 2.7e-39 NP_001273974 (OMIM: 609288) endophilin-B2 isoform ( 404) 897 161.7 2.7e-39 XP_006717253 (OMIM: 609288) PREDICTED: endophilin- ( 423) 897 161.7 2.8e-39 XP_006717251 (OMIM: 609288) PREDICTED: endophilin- ( 428) 897 161.7 2.8e-39 NP_064530 (OMIM: 609288) endophilin-B2 isoform b [ ( 395) 896 161.5 3e-39 NP_001273975 (OMIM: 609288) endophilin-B2 isoform ( 395) 896 161.5 3e-39 XP_005252155 (OMIM: 609288) PREDICTED: endophilin- ( 400) 896 161.5 3e-39 XP_006717252 (OMIM: 609288) PREDICTED: endophilin- ( 424) 896 161.5 3.2e-39 NP_003016 (OMIM: 601768) endophilin-A2 isoform 1 [ ( 368) 422 82.1 2.1e-15 XP_016882635 (OMIM: 601768) PREDICTED: endophilin- ( 358) 416 81.1 4.2e-15 XP_005252158 (OMIM: 609288) PREDICTED: endophilin- ( 125) 399 77.9 1.4e-14 XP_011526485 (OMIM: 601768) PREDICTED: endophilin- ( 333) 363 72.2 1.9e-12 NP_003017 (OMIM: 604465) endophilin-A1 [Homo sapie ( 352) 312 63.7 7.2e-10 NP_001311111 (OMIM: 603362) endophilin-A3 isoform ( 360) 311 63.6 8.2e-10 NP_003018 (OMIM: 603362) endophilin-A3 isoform a [ ( 347) 306 62.7 1.4e-09 XP_011516307 (OMIM: 604465) PREDICTED: endophilin- ( 386) 303 62.3 2.2e-09 NP_001288038 (OMIM: 603362) endophilin-A3 isoform ( 355) 300 61.7 2.9e-09 NP_001311112 (OMIM: 603362) endophilin-A3 isoform ( 355) 300 61.7 2.9e-09 XP_011520191 (OMIM: 603362) PREDICTED: endophilin- ( 355) 300 61.7 2.9e-09 NP_001186872 (OMIM: 601768) endophilin-A2 isoform ( 320) 274 57.3 5.5e-08 XP_011520193 (OMIM: 603362) PREDICTED: endophilin- ( 237) 262 55.2 1.8e-07 XP_011520194 (OMIM: 603362) PREDICTED: endophilin- ( 217) 261 55.0 1.9e-07 NP_001311113 (OMIM: 603362) endophilin-A3 isoform ( 312) 258 54.6 3.4e-07 NP_001311115 (OMIM: 603362) endophilin-A3 isoform ( 312) 258 54.6 3.4e-07 NP_001288037 (OMIM: 603362) endophilin-A3 isoform ( 278) 227 49.4 1.2e-05 XP_016877975 (OMIM: 603362) PREDICTED: endophilin- ( 278) 227 49.4 1.2e-05 NP_001311116 (OMIM: 603362) endophilin-A3 isoform ( 278) 227 49.4 1.2e-05 NP_001311114 (OMIM: 603362) endophilin-A3 isoform ( 278) 227 49.4 1.2e-05 >>NP_057093 (OMIM: 609287) endophilin-B1 isoform 1 [Homo (365 aa) initn: 2333 init1: 2333 opt: 2333 Z-score: 2125.5 bits: 401.9 E(85289): 1.2e-111 Smith-Waterman score: 2333; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 KAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 CYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 CYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 LKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITY 310 320 330 340 350 360 pF1KA0 LELLN ::::: NP_057 LELLN >>NP_001193582 (OMIM: 609287) endophilin-B1 isoform 4 [H (265 aa) initn: 1691 init1: 1691 opt: 1691 Z-score: 1546.9 bits: 294.4 E(85289): 2e-79 Smith-Waterman score: 1691; 100.0% identity (100.0% similar) in 265 aa overlap (101-365:1-265) 80 90 100 110 120 130 pF1KA0 PNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGT :::::::::::::::::::::::::::::: NP_001 MIDAGTEFGPGTAYGNALIKCGETQKRIGT 10 20 30 140 150 160 170 180 190 pF1KA0 ADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KA0 SEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQK 100 110 120 130 140 150 260 270 280 290 300 310 pF1KA0 QLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKA 160 170 180 190 200 210 320 330 340 350 360 pF1KA0 RVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN 220 230 240 250 260 >>XP_005252157 (OMIM: 609288) PREDICTED: endophilin-B2 i (379 aa) initn: 1547 init1: 892 opt: 1230 Z-score: 1127.9 bits: 217.4 E(85289): 4.4e-56 Smith-Waterman score: 1541; 62.9% identity (87.6% similar) in 380 aa overlap (4-365:1-379) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM ::::.::::.::: :..:::::::::.:::::::::::.::::..:. :: :::::. XP_005 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKIL 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK .::::::::::.::.:::.:::::::.:::..: :::.::: ::..:.:: : ::..::: XP_005 RQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK .:..:..:.:.:..:.:....::::::::.:::.:::.:::.::::.:::::: :.::: XP_005 VAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLK 120 130 140 150 160 170 190 200 210 220 230 pF1KA0 KAKAAETR--------NSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVE ::::::.. ...:::::..:.:::::::.::::::::::::..:::::..::. XP_005 KAKAAEAKATLWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVK 180 190 200 210 220 230 240 250 260 270 280 pF1KA0 AQMTYYAQCYQYMLDLQKQLGS-----FPSNYLSNNNQTSVTPVPSVLPNAIGSSAMAST .: :::::::..:::::::::: ::........ .: :. :. :.. ... . XP_005 SQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPAS-PPLSSTSPTTAAATMPVVP 240 250 260 270 280 290 290 300 310 320 330 340 pF1KA0 SGLVITSPSNLSD-LKEC----SGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDS : .. :.. : :.: ::.:::::::::.::.:.::.:::::.:::.:. ::: XP_005 SVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDP 300 310 320 330 340 350 350 360 pF1KA0 DWLMGERGNQKGKVPITYLELLN :::.:::::.:::::.::::::. XP_005 DWLIGERGNKKGKVPVTYLELLS 360 370 >>XP_011539840 (OMIM: 609287) PREDICTED: endophilin-B1 i (378 aa) initn: 2319 init1: 1209 opt: 1220 Z-score: 1118.9 bits: 215.7 E(85289): 1.4e-55 Smith-Waterman score: 2297; 96.6% identity (96.6% similar) in 378 aa overlap (1-365:1-378) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 130 140 150 160 170 180 190 200 210 220 pF1KA0 KAKAAETRNS-------------SEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCL :::::::::: ::::::::::::::::::::::::::::::::::::: XP_011 KAKAAETRNSQLNSARLEGDNIMSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 NDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMAST 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 SGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMG 310 320 330 340 350 360 350 360 pF1KA0 ERGNQKGKVPITYLELLN :::::::::::::::::: XP_011 ERGNQKGKVPITYLELLN 370 >>XP_016856899 (OMIM: 609287) PREDICTED: endophilin-B1 i (219 aa) initn: 1214 init1: 1214 opt: 1214 Z-score: 1116.6 bits: 214.5 E(85289): 1.9e-55 Smith-Waterman score: 1214; 89.0% identity (93.6% similar) in 219 aa overlap (1-219:1-219) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 KAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQ ::::::::::. . :. ... :: . . ..:: XP_016 KAKAAETRNSQLNSARLEGDNIMIWAEEVTKAYQTLTST 190 200 210 250 260 270 280 290 300 pF1KA0 CYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSD >>XP_016856898 (OMIM: 609287) PREDICTED: endophilin-B1 i (235 aa) initn: 1209 init1: 1209 opt: 1212 Z-score: 1114.4 bits: 214.2 E(85289): 2.5e-55 Smith-Waterman score: 1212; 97.0% identity (98.5% similar) in 197 aa overlap (1-197:1-197) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 KAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQ ::::::::::. . :. XP_016 KAKAAETRNSQLNSARLEGDNIMVNFSYMLNFLHVKWLKIWAEEVTKAYQTLTST 190 200 210 220 230 >>NP_001193581 (OMIM: 609287) endophilin-B1 isoform 3 [H (386 aa) initn: 1212 init1: 1212 opt: 1212 Z-score: 1111.5 bits: 214.3 E(85289): 3.6e-55 Smith-Waterman score: 2281; 94.6% identity (94.6% similar) in 386 aa overlap (1-365:1-386) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 130 140 150 160 170 180 190 200 210 pF1KA0 KAKAAETRNS---------------------SEQELRITQSEFDRQAEITRLLLEGISST :::::::::: ::::::::::::::::::::::::::::: NP_001 KAKAAETRNSQLNSARLEGDNIMIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISST 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 HAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAI 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 GSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVG 310 320 330 340 350 360 340 350 360 pF1KA0 MDSDWLMGERGNQKGKVPITYLELLN :::::::::::::::::::::::::: NP_001 MDSDWLMGERGNQKGKVPITYLELLN 370 380 >>NP_001193580 (OMIM: 609287) endophilin-B1 isoform 2 [H (394 aa) initn: 1212 init1: 1212 opt: 1212 Z-score: 1111.4 bits: 214.4 E(85289): 3.6e-55 Smith-Waterman score: 2265; 92.6% identity (92.6% similar) in 394 aa overlap (1-365:1-394) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 130 140 150 160 170 180 190 200 210 pF1KA0 KAKAAETRNS-----------------------------SEQELRITQSEFDRQAEITRL :::::::::: ::::::::::::::::::::: NP_001 KAKAAETRNSQLNSARLEGDNIMVNFSYMLNFLHVKWLKSEQELRITQSEFDRQAEITRL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 LLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPV 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 PSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEV 310 320 330 340 350 360 340 350 360 pF1KA0 ITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN :::::::::::::::::::::::::::::::::: NP_001 ITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN 370 380 390 >>XP_006710735 (OMIM: 609287) PREDICTED: endophilin-B1 i (402 aa) initn: 1212 init1: 1212 opt: 1212 Z-score: 1111.3 bits: 214.4 E(85289): 3.7e-55 Smith-Waterman score: 2221; 90.7% identity (90.7% similar) in 397 aa overlap (1-360:1-397) 10 20 30 40 50 60 pF1KA0 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 130 140 150 160 170 180 190 200 pF1KA0 KAKAAETRNS-------------------------------------SEQELRITQSEFD :::::::::: ::::::::::::: XP_006 KAKAAETRNSQLNSARLEGDNIMVNFSYMLNFLHVKWLKIWAEEVTKSEQELRITQSEFD 190 200 210 220 230 240 210 220 230 240 250 260 pF1KA0 RQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNN 250 260 270 280 290 300 270 280 290 300 310 320 pF1KA0 NQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTE 310 320 330 340 350 360 330 340 350 360 pF1KA0 LSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN ::::::::::::::::::::::::::::::::::::: XP_006 LSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN 370 380 390 400 >>XP_016856897 (OMIM: 609287) PREDICTED: endophilin-B1 i (286 aa) initn: 1131 init1: 1131 opt: 1138 Z-score: 1046.3 bits: 201.9 E(85289): 1.5e-51 Smith-Waterman score: 1639; 92.7% identity (92.7% similar) in 286 aa overlap (101-365:1-286) 80 90 100 110 120 130 pF1KA0 PNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGT :::::::::::::::::::::::::::::: XP_016 MIDAGTEFGPGTAYGNALIKCGETQKRIGT 10 20 30 140 150 160 170 180 190 pF1KA0 ADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNS 40 50 60 70 80 90 200 210 220 pF1KA0 ---------------------SEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLND ::::::::::::::::::::::::::::::::::::::: XP_016 QLNSARLEGDNIMIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLND 100 110 120 130 140 150 230 240 250 260 270 280 pF1KA0 FVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSG 160 170 180 190 200 210 290 300 310 320 330 340 pF1KA0 LVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGER 220 230 240 250 260 270 350 360 pF1KA0 GNQKGKVPITYLELLN :::::::::::::::: XP_016 GNQKGKVPITYLELLN 280 365 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:08:58 2016 done: Wed Nov 2 19:08:59 2016 Total Scan time: 8.030 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]