Result of FASTA (omim) for
pF1KA0551
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0551, 1360 aa
1>>>pF1KA0551 1360 - 1360 aa - 1360 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.2354+/-0.000637; mu= -29.0114+/- 0.040
mean_var=1024.2120+/-220.506, 0's: 0 Z-trim(122.1): 874 B-trim: 2219 in 1/58
Lambda= 0.040076
statistics sampled from 38350 (39617) to 38350 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.465), width: 16
Scan time: 15.120
The best scores are: opt bits E(85289)
NP_055843 (OMIM: 610005,617028) TRAF2 and NCK-inte (1360) 9018 538.6 1.1e-151
NP_001155032 (OMIM: 610005,617028) TRAF2 and NCK-i (1352) 8943 534.3 2.3e-150
NP_001155033 (OMIM: 610005,617028) TRAF2 and NCK-i (1331) 6028 365.8 1.2e-99
NP_001155034 (OMIM: 610005,617028) TRAF2 and NCK-i (1323) 5919 359.5 9.6e-98
NP_001155035 (OMIM: 610005,617028) TRAF2 and NCK-i (1305) 5232 319.7 8.6e-86
NP_001155037 (OMIM: 610005,617028) TRAF2 and NCK-i (1276) 5217 318.8 1.5e-85
NP_001155038 (OMIM: 610005,617028) TRAF2 and NCK-i (1268) 5122 313.4 6.9e-84
NP_001155036 (OMIM: 610005,617028) TRAF2 and NCK-i (1297) 5092 311.6 2.3e-83
XP_006721594 (OMIM: 609426) PREDICTED: misshapen-l (1361) 5054 309.5 1.1e-82
XP_006721595 (OMIM: 609426) PREDICTED: misshapen-l (1360) 5051 309.3 1.2e-82
XP_016880193 (OMIM: 609426) PREDICTED: misshapen-l (1358) 5036 308.4 2.3e-82
XP_016860838 (OMIM: 604666) PREDICTED: mitogen-act (1352) 5007 306.7 7.2e-82
XP_016880196 (OMIM: 609426) PREDICTED: misshapen-l (1306) 4736 291.0 3.7e-77
XP_016880197 (OMIM: 609426) PREDICTED: misshapen-l (1290) 4646 285.8 1.3e-75
XP_005264105 (OMIM: 604666) PREDICTED: mitogen-act (1384) 3305 208.3 3.1e-52
XP_005264117 (OMIM: 604666) PREDICTED: mitogen-act (1280) 2912 185.6 2e-45
XP_005264126 (OMIM: 604666) PREDICTED: mitogen-act (1209) 2908 185.3 2.3e-45
NP_663719 (OMIM: 604666) mitogen-activated protein (1273) 2908 185.3 2.4e-45
XP_016860845 (OMIM: 604666) PREDICTED: mitogen-act (1281) 2908 185.3 2.4e-45
XP_016860839 (OMIM: 604666) PREDICTED: mitogen-act (1330) 2906 185.3 2.6e-45
XP_016860857 (OMIM: 604666) PREDICTED: mitogen-act (1211) 2895 184.6 3.9e-45
NP_663720 (OMIM: 604666) mitogen-activated protein (1212) 2893 184.5 4.2e-45
XP_005264116 (OMIM: 604666) PREDICTED: mitogen-act (1284) 2893 184.5 4.3e-45
XP_011522208 (OMIM: 609426) PREDICTED: misshapen-l (1329) 2884 184.0 6.4e-45
XP_016860843 (OMIM: 604666) PREDICTED: mitogen-act (1299) 2850 182.0 2.5e-44
XP_016860841 (OMIM: 604666) PREDICTED: mitogen-act (1307) 2819 180.2 8.5e-44
XP_016860842 (OMIM: 604666) PREDICTED: mitogen-act (1306) 2815 180.0 1e-43
XP_016860862 (OMIM: 604666) PREDICTED: mitogen-act (1163) 2793 178.7 2.2e-43
NP_004825 (OMIM: 604666) mitogen-activated protein (1165) 2791 178.5 2.4e-43
XP_016860861 (OMIM: 604666) PREDICTED: mitogen-act (1166) 2790 178.5 2.5e-43
XP_016860846 (OMIM: 604666) PREDICTED: mitogen-act (1276) 2790 178.5 2.7e-43
XP_016860847 (OMIM: 604666) PREDICTED: mitogen-act (1275) 2786 178.3 3.1e-43
XP_016860856 (OMIM: 604666) PREDICTED: mitogen-act (1234) 2778 177.8 4.2e-43
XP_006712928 (OMIM: 604666) PREDICTED: mitogen-act (1307) 2778 177.8 4.4e-43
NP_001229489 (OMIM: 604666) mitogen-activated prot (1235) 2775 177.6 4.8e-43
XP_016860855 (OMIM: 604666) PREDICTED: mitogen-act (1243) 2775 177.6 4.8e-43
XP_016860844 (OMIM: 604666) PREDICTED: mitogen-act (1296) 2775 177.7 4.9e-43
XP_005264125 (OMIM: 604666) PREDICTED: mitogen-act (1227) 2774 177.6 5e-43
XP_005264123 (OMIM: 604666) PREDICTED: mitogen-act (1229) 2772 177.5 5.4e-43
XP_005264122 (OMIM: 604666) PREDICTED: mitogen-act (1230) 2771 177.4 5.6e-43
XP_005264115 (OMIM: 604666) PREDICTED: mitogen-act (1312) 2769 177.3 6.3e-43
XP_005264114 (OMIM: 604666) PREDICTED: mitogen-act (1315) 2768 177.3 6.6e-43
XP_016860840 (OMIM: 604666) PREDICTED: mitogen-act (1311) 2766 177.1 7.2e-43
XP_005264109 (OMIM: 604666) PREDICTED: mitogen-act (1337) 2761 176.9 8.9e-43
XP_016860851 (OMIM: 604666) PREDICTED: mitogen-act (1265) 2760 176.8 8.9e-43
XP_016860849 (OMIM: 604666) PREDICTED: mitogen-act (1273) 2760 176.8 8.9e-43
XP_016860854 (OMIM: 604666) PREDICTED: mitogen-act (1243) 2759 176.7 9.1e-43
NP_001229488 (OMIM: 604666) mitogen-activated prot (1239) 2758 176.7 9.5e-43
XP_005264107 (OMIM: 604666) PREDICTED: mitogen-act (1338) 2759 176.8 9.6e-43
XP_016860850 (OMIM: 604666) PREDICTED: mitogen-act (1266) 2758 176.7 9.6e-43
>>NP_055843 (OMIM: 610005,617028) TRAF2 and NCK-interact (1360 aa)
initn: 9018 init1: 9018 opt: 9018 Z-score: 2844.0 bits: 538.6 E(85289): 1.1e-151
Smith-Waterman score: 9018; 100.0% identity (100.0% similar) in 1360 aa overlap (1-1360:1-1360)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
NP_055 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1330 1340 1350 1360
>>NP_001155032 (OMIM: 610005,617028) TRAF2 and NCK-inter (1352 aa)
initn: 5289 init1: 5289 opt: 8943 Z-score: 2820.6 bits: 534.3 E(85289): 2.3e-150
Smith-Waterman score: 8943; 99.4% identity (99.4% similar) in 1360 aa overlap (1-1360:1-1352)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
:::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
790 800 810 820 830
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
NP_001 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1320 1330 1340 1350
>>NP_001155033 (OMIM: 610005,617028) TRAF2 and NCK-inter (1331 aa)
initn: 5911 init1: 5911 opt: 6028 Z-score: 1909.9 bits: 365.8 E(85289): 1.2e-99
Smith-Waterman score: 8771; 97.9% identity (97.9% similar) in 1360 aa overlap (1-1360:1-1331)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
:::::::::::::::::::::::::: :::::
NP_001 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
430 440 450
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
NP_001 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1300 1310 1320 1330
>>NP_001155034 (OMIM: 610005,617028) TRAF2 and NCK-inter (1323 aa)
initn: 6747 init1: 3742 opt: 5919 Z-score: 1875.8 bits: 359.5 E(85289): 9.6e-98
Smith-Waterman score: 8696; 97.3% identity (97.3% similar) in 1360 aa overlap (1-1360:1-1323)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
:::::::::::::::::::::::::: :::::
NP_001 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
430 440 450
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
:::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
760 770 780 790 800
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
810 820 830 840 850 860
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
NP_001 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1290 1300 1310 1320
>>NP_001155035 (OMIM: 610005,617028) TRAF2 and NCK-inter (1305 aa)
initn: 5073 init1: 5073 opt: 5232 Z-score: 1661.2 bits: 319.7 E(85289): 8.6e-86
Smith-Waterman score: 8522; 96.0% identity (96.0% similar) in 1360 aa overlap (1-1360:1-1305)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
490 500 510 520 530
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
:::::::::
NP_001 ---------------------------------------------------IPHLVAVKS
540
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
550 560 570 580 590 600
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
610 620 630 640 650 660
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
670 680 690 700 710 720
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
730 740 750 760 770 780
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
790 800 810 820 830 840
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
850 860 870 880 890 900
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
910 920 930 940 950 960
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
970 980 990 1000 1010 1020
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1030 1040 1050 1060 1070 1080
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1090 1100 1110 1120 1130 1140
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1150 1160 1170 1180 1190 1200
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1210 1220 1230 1240 1250 1260
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
NP_001 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1270 1280 1290 1300
>>NP_001155037 (OMIM: 610005,617028) TRAF2 and NCK-inter (1276 aa)
initn: 8078 init1: 5073 opt: 5217 Z-score: 1656.7 bits: 318.8 E(85289): 1.5e-85
Smith-Waterman score: 8275; 93.8% identity (93.8% similar) in 1360 aa overlap (1-1360:1-1276)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
:::::::::::::::::::::::::: :::::
NP_001 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
430 440 450
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
460 470 480 490 500
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
:::::::::
NP_001 ---------------------------------------------------IPHLVAVKS
510
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
700 710 720 730 740 750
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
760 770 780 790 800 810
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
NP_001 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1240 1250 1260 1270
>>NP_001155038 (OMIM: 610005,617028) TRAF2 and NCK-inter (1268 aa)
initn: 6747 init1: 3742 opt: 5122 Z-score: 1627.0 bits: 313.4 E(85289): 6.9e-84
Smith-Waterman score: 8200; 93.2% identity (93.2% similar) in 1360 aa overlap (1-1360:1-1268)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
:::::::::::::::::::::::::: :::::
NP_001 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
430 440 450
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
460 470 480 490 500
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
:::::::::
NP_001 ---------------------------------------------------IPHLVAVKS
510
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
:::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
700 710 720 730 740
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
750 760 770 780 790 800
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
810 820 830 840 850 860
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
870 880 890 900 910 920
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
930 940 950 960 970 980
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
990 1000 1010 1020 1030 1040
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1050 1060 1070 1080 1090 1100
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1110 1120 1130 1140 1150 1160
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1170 1180 1190 1200 1210 1220
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
NP_001 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1230 1240 1250 1260
>>NP_001155036 (OMIM: 610005,617028) TRAF2 and NCK-inter (1297 aa)
initn: 7304 init1: 3742 opt: 5092 Z-score: 1617.5 bits: 311.6 E(85289): 2.3e-83
Smith-Waterman score: 8447; 95.4% identity (95.4% similar) in 1360 aa overlap (1-1360:1-1297)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
490 500 510 520 530
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
:::::::::
NP_001 ---------------------------------------------------IPHLVAVKS
540
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
550 560 570 580 590 600
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
610 620 630 640 650 660
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
670 680 690 700 710 720
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
:::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
730 740 750 760 770
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
780 790 800 810 820 830
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
840 850 860 870 880 890
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
900 910 920 930 940 950
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
960 970 980 990 1000 1010
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1020 1030 1040 1050 1060 1070
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1080 1090 1100 1110 1120 1130
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1140 1150 1160 1170 1180 1190
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1200 1210 1220 1230 1240 1250
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
NP_001 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1260 1270 1280 1290
>>XP_006721594 (OMIM: 609426) PREDICTED: misshapen-like (1361 aa)
initn: 4432 init1: 2110 opt: 5054 Z-score: 1605.4 bits: 309.5 E(85289): 1.1e-82
Smith-Waterman score: 5692; 65.3% identity (80.5% similar) in 1416 aa overlap (1-1360:1-1361)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
:.. .::::::.:::::::::::::::::.:::::::::::::::::::::::::::::
XP_006 MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::.::: :::::::::::::::::::.:::
XP_006 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
:::.:::. ::::::::::::.::: ::::::::::::::::::::::::::::::::::
XP_006 KGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
:::::::::::::::::::::::::::::::..::.::::::::::::::::::::::::
XP_006 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::: :::::::::::: .::..::.:.. .:: ::::.: :::::::.::::::
XP_006 ALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRI
250 260 270 280 290 300
310 320 330 340 350
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEEN-DSGEPSSILNLPGESTLRRDFLRLQL
::::::::..::::::.::::::::::::.. . . ::::::.:.::::::::.:::::
XP_006 QLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 ANKERSEALRRQQL--EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRK
:: ::::..:: .::::. : : ..:: .::.:::::::.:::.:::::::.: ::
XP_006 ENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRK
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 QQEREQRRHYEEQ--MRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEY
::.::.:. :.. .:::::::.::.::::::..::::::::::::::::.::::::::
XP_006 LQEKEQQRRLEDMQALRREEERRQAEREQEYIRHRLEEEQRQLEILQQQLLQEQALLLEY
430 440 450 460 470 480
480 490 500 510 520
pF1KA0 KRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQR----------PVEKKPLYHYKEGM
::::::::::.:::::::.::. :: :::.:.:.:. : ..:::::: .::
XP_006 KRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGM
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA0 SPSEKPAWAKEVEERSRLNRQ-SSPAMPHKVANRISDPNLPPRSESFSISGVQP-ARTPP
.:..:::::.:::::.:.:.: .:: : .. .: .: : . : : ..:::
XP_006 NPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPG--PPG--PLSQTPP
550 560 570 580 590
590 600 610 620
pF1KA0 MLRPVDPQ-------IPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALN---------
: :::.:: . : : .: . . :::...:::..:..: . .
XP_006 MQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAIPAPT
600 610 620 630 640 650
630 640 650 660 670 680
pF1KA0 -VTSHRVEMPRQNSDPTSENP-PLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALAR
. : : . :::::::::.: : : . .:.: ... ::::::::.::. ::
XP_006 ATPSARGAVIRQNSDPTSEGPGPSP------NPPAWVRPDNEAPPKVPQRTSSIATALNT
660 670 680 690 700 710
690 700 710 720 730 740
pF1KA0 KNSPGNGSALGPRLGSQPIRASNPDL---RRTEPILESPLQRTSS--GSSSSSSTPSSQP
... :. : . : ..: : .. ::.: .: .. : ..::.:. .
XP_006 SGAGGSRPAQAVR--ARPRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNASSNPDLRR
720 730 740 750 760
750 760 770 780
pF1KA0 SSQGGSQ-----PGS-----QAGSSERTRVRANSKSEGSPVLPHEPA-KVKPEESRDITR
:. : . :.: :::: ::.:: ..:: ..:::: :. :.::.. : .:
XP_006 SDPGWERSDSVLPASHGHLPQAGSLERNRVGVSSKPDSSPVLS--PGNKAKPDDHR--SR
770 780 790 800 810 820
790 800 810 820 830 840
pF1KA0 PSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSEEEEEDGESE
:.:::.. .: :.: ..:. :: ::. :::::::: ::::..::.::.
XP_006 PGRPADF---------VL---LKERTLDEAPRPPKKAMDYSSSSEEVESSEDDEEEGEGG
830 840 850 860 870
850 860 870 880 890 900
pF1KA0 THDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLE--TSHADSFSGSISREGTLMIRE
.:. : : :. .... .:. . .: .: :. ..: ::.....
XP_006 PAEGS---RDTP-----GGRSDGDTDSVSTMVVHDVEEITGTQPPYGG-----GTMVVQR
880 890 900 910
910 920 930 940 950 960
pF1KA0 TSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSGTEYGMG-
: :.. :.::::.. ::::.:: :::: ::. : :.. :: . :
XP_006 TPEEERNLLHADSNGYT---NLPDVVQPSHSP----TENSKGQSPPSKD-GSGDYQSRGL
920 930 940 950 960 970
970 980 990 1000 1010 1020
pF1KA0 --SSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKISVVN
. :.::: ::: .:: . . .. .:: .: : .: . . .:: ::::
XP_006 VKAPGKSSFTMFVDLGIYQPGGSGDS-----IPITALVGGEGTRLDQLQYD-VRKGSVVN
980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLIN
::::: : ::.:::::::::::::::::::::::::::::::::::::::::::::.::.
XP_006 VNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 RRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGC
::::::::::::::.:.:::::.:::::::::::::.:::::::::::::: ::::.:::
XP_006 RRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDMEGC
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 IHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQR
::.:::::::::::::::..::.:::::::::::::::::::: :.:::::::::::::
XP_006 GHYRVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 LKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVY
::::.:: .:::..::::::::::::: :::..::::::..::.:::::::.::::::::
XP_006 LKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVY
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 VNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRL
::::::: ::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_006 VNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360
pF1KA0 KFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
:::::::::::::::::::::::.::::::: .:::
XP_006 KFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW
1330 1340 1350 1360
>>XP_006721595 (OMIM: 609426) PREDICTED: misshapen-like (1360 aa)
initn: 3807 init1: 3807 opt: 5051 Z-score: 1604.5 bits: 309.3 E(85289): 1.2e-82
Smith-Waterman score: 5697; 65.3% identity (80.4% similar) in 1416 aa overlap (1-1360:1-1360)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
:.. .::::::.:::::::::::::::::.:::::::::::::::::::::::::::::
XP_006 MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::.::: :::::::::::::::::::.:::
XP_006 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
:::.:::. ::::::::::::.::: ::::::::::::::::::::::::::::::::::
XP_006 KGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
:::::::::::::::::::::::::::::::..::.::::::::::::::::::::::::
XP_006 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::: :::::::::::: .::..::.:.. .:: ::::.: :::::::.::::::
XP_006 ALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRI
250 260 270 280 290 300
310 320 330 340 350
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEEN-DSGEPSSILNLPGESTLRRDFLRLQL
::::::::..::::::.::::::::::::.. . . ::::::.:.::::::::.:::::
XP_006 QLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 ANKERSEALRRQQL--EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRK
:: ::::..:: .::::. : : ..:: .::.:::::::.:::.:::::::.: ::
XP_006 ENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRK
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 QQEREQRRHYEEQ--MRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEY
::.::.:. :.. .:::::::.::.::::::..::::::::::::::::.::::::::
XP_006 LQEKEQQRRLEDMQALRREEERRQAEREQEYIRHRLEEEQRQLEILQQQLLQEQALLLEY
430 440 450 460 470 480
480 490 500 510 520
pF1KA0 KRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQR----------PVEKKPLYHYKEGM
::::::::::.:::::::.::. :: :::.:.:.:. : ..:::::: .::
XP_006 KRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGM
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA0 SPSEKPAWAKEVEERSRLNRQ-SSPAMPHKVANRISDPNLPPRSESFSISGVQP-ARTPP
.:..:::::.:::::.:.:.: .:: : .. .: .: : . : : ..:::
XP_006 NPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPG--PPG--PLSQTPP
550 560 570 580 590
590 600 610 620
pF1KA0 MLRPVDPQ-------IPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALN---------
: :::.:: . : : .: . . :::...:::..:..: . .
XP_006 MQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAIPAPT
600 610 620 630 640 650
630 640 650 660 670 680
pF1KA0 -VTSHRVEMPRQNSDPTSENP-PLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALAR
. : : . :::::::::.: : : . .:.: ... ::::::::.::. ::
XP_006 ATPSARGAVIRQNSDPTSEGPGPSP------NPPAWVRPDNEAPPKVPQRTSSIATALNT
660 670 680 690 700 710
690 700 710 720 730 740
pF1KA0 KNSPGNGSALGPRLGSQPIRASNPDL---RRTEPILESPLQRTSS--GSSSSSSTPSSQP
... :. : . : ..: : .. ::.: .: .. : ..::.:. .
XP_006 SGAGGSRPAQAVR--ARPRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNASSNPDLRR
720 730 740 750 760
750 760 770 780
pF1KA0 SSQGGSQ-----PGS-----QAGSSERTRVRANSKSEGSPVLPHEPA-KVKPEESRDITR
:. : . :.: :::: ::.:: ..:: ..:::: :. :.::.. : .:
XP_006 SDPGWERSDSVLPASHGHLPQAGSLERNRVGVSSKPDSSPVLS--PGNKAKPDDHR--SR
770 780 790 800 810 820
790 800 810 820 830 840
pF1KA0 PSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSEEEEEDGESE
:.:::.. .: :.: ..:. :: ::. :::::::: ::::..::.::.
XP_006 PGRPADF---------VL---LKERTLDEAPRPPKKAMDYSSSSEEVESSEDDEEEGEGG
830 840 850 860 870
850 860 870 880 890 900
pF1KA0 THDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLE--TSHADSFSGSISREGTLMIRE
.:. : : : :.... .. .: : .: :. ..: ::.....
XP_006 PAEGS-------RDTPGGRDGDTDSVSTMVV--HDVEEITGTQPPYGG-----GTMVVQR
880 890 900 910
910 920 930 940 950 960
pF1KA0 TSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSGTEYGMG-
: :.. :.::::.. ::::.:: :::: ::. : :.. :: . :
XP_006 TPEEERNLLHADSNGYT---NLPDVVQPSHSP----TENSKGQSPPSKD-GSGDYQSRGL
920 930 940 950 960 970
970 980 990 1000 1010 1020
pF1KA0 --SSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKISVVN
. :.::: ::: .:: . . .. .:: .: : .: . . .:: ::::
XP_006 VKAPGKSSFTMFVDLGIYQPGGSGDS-----IPITALVGGEGTRLDQLQYD-VRKGSVVN
980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLIN
::::: : ::.:::::::::::::::::::::::::::::::::::::::::::::.::.
XP_006 VNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 RRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGC
::::::::::::::.:.:::::.:::::::::::::.:::::::::::::: ::::.:::
XP_006 RRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDMEGC
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 IHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQR
::.:::::::::::::::..::.:::::::::::::::::::: :.:::::::::::::
XP_006 GHYRVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 LKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVY
::::.:: .:::..::::::::::::: :::..::::::..::.:::::::.::::::::
XP_006 LKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVY
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 VNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRL
::::::: ::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_006 VNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360
pF1KA0 KFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
:::::::::::::::::::::::.::::::: .:::
XP_006 KFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW
1330 1340 1350 1360
1360 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:41:27 2016 done: Thu Nov 3 09:41:29 2016
Total Scan time: 15.120 Total Display time: 0.570
Function used was FASTA [36.3.4 Apr, 2011]