FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0561, 1309 aa 1>>>pF1KA0561 1309 - 1309 aa - 1309 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.1815+/-0.000543; mu= -17.9663+/- 0.034 mean_var=900.9905+/-193.071, 0's: 0 Z-trim(123.8): 567 B-trim: 0 in 0/59 Lambda= 0.042728 statistics sampled from 43715 (44368) to 43715 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.52), width: 16 Scan time: 19.540 The best scores are: opt bits E(85289) NP_055831 (OMIM: 612258) microtubule-associated se (1309) 8735 555.3 9.8e-157 XP_005259884 (OMIM: 612258) PREDICTED: microtubule (1315) 8592 546.5 4.4e-154 XP_016881999 (OMIM: 612258) PREDICTED: microtubule (1403) 8583 546.0 6.8e-154 XP_006722763 (OMIM: 612258) PREDICTED: microtubule (1314) 8575 545.5 9.2e-154 XP_016881998 (OMIM: 612258) PREDICTED: microtubule (1410) 8559 544.5 1.9e-153 XP_016882005 (OMIM: 612258) PREDICTED: microtubule (1409) 8542 543.5 3.9e-153 XP_016882001 (OMIM: 612258) PREDICTED: microtubule (1318) 7275 465.3 1.2e-129 XP_016882002 (OMIM: 612258) PREDICTED: microtubule (1317) 7258 464.3 2.5e-129 XP_005259881 (OMIM: 612258) PREDICTED: microtubule (1325) 7251 463.9 3.4e-129 XP_005259882 (OMIM: 612258) PREDICTED: microtubule (1324) 7234 462.8 7.1e-129 XP_016881996 (OMIM: 612258) PREDICTED: microtubule (1412) 7123 456.0 8.5e-127 XP_005259883 (OMIM: 612258) PREDICTED: microtubule (1323) 7115 455.5 1.1e-126 XP_005259880 (OMIM: 612258) PREDICTED: microtubule (1331) 7108 455.0 1.5e-126 XP_016881997 (OMIM: 612258) PREDICTED: microtubule (1411) 7106 455.0 1.7e-126 XP_006722762 (OMIM: 612258) PREDICTED: microtubule (1419) 7099 454.5 2.4e-126 XP_016882000 (OMIM: 612258) PREDICTED: microtubule (1347) 7095 454.3 2.7e-126 XP_011526125 (OMIM: 612258) PREDICTED: microtubule (1355) 7095 454.3 2.7e-126 XP_016881995 (OMIM: 612258) PREDICTED: microtubule (1418) 7082 453.5 4.9e-126 XP_016882003 (OMIM: 612258) PREDICTED: microtubule (1243) 6768 434.1 3e-120 XP_016882004 (OMIM: 612258) PREDICTED: microtubule (1243) 6768 434.1 3e-120 XP_006722761 (OMIM: 612258) PREDICTED: microtubule (1243) 6768 434.1 3e-120 NP_055927 (OMIM: 612257) microtubule-associated se (1798) 3846 254.1 6.4e-66 NP_001306174 (OMIM: 612257) microtubule-associated (1797) 3841 253.8 7.9e-66 XP_011526107 (OMIM: 612256) PREDICTED: microtubule (1566) 3802 251.3 3.8e-65 XP_011539370 (OMIM: 612257) PREDICTED: microtubule (1636) 3791 250.7 6.3e-65 XP_016856243 (OMIM: 612257) PREDICTED: microtubule (1683) 3791 250.7 6.4e-65 XP_011539364 (OMIM: 612257) PREDICTED: microtubule (1863) 3791 250.7 6.9e-65 NP_055790 (OMIM: 612256) microtubule-associated se (1570) 3726 246.7 9.9e-64 XP_011539369 (OMIM: 612257) PREDICTED: microtubule (1643) 3671 243.3 1.1e-62 NP_001311250 (OMIM: 612257) microtubule-associated (1644) 3671 243.3 1.1e-62 XP_006710540 (OMIM: 612257) PREDICTED: microtubule (1655) 3671 243.3 1.1e-62 XP_016856244 (OMIM: 612257) PREDICTED: microtubule (1662) 3671 243.3 1.1e-62 XP_016856242 (OMIM: 612257) PREDICTED: microtubule (1690) 3671 243.3 1.1e-62 XP_005270713 (OMIM: 612257) PREDICTED: microtubule (1711) 3671 243.3 1.1e-62 XP_005270712 (OMIM: 612257) PREDICTED: microtubule (1720) 3671 243.3 1.1e-62 XP_016856241 (OMIM: 612257) PREDICTED: microtubule (1727) 3671 243.3 1.1e-62 XP_011539367 (OMIM: 612257) PREDICTED: microtubule (1731) 3671 243.3 1.1e-62 NP_001311249 (OMIM: 612257) microtubule-associated (1805) 3671 243.3 1.1e-62 XP_011539366 (OMIM: 612257) PREDICTED: microtubule (1817) 3671 243.3 1.1e-62 XP_011539365 (OMIM: 612257) PREDICTED: microtubule (1820) 3671 243.3 1.1e-62 XP_011539361 (OMIM: 612257) PREDICTED: microtubule (1870) 3671 243.3 1.2e-62 XP_011539363 (OMIM: 612257) PREDICTED: microtubule (1869) 3666 243.0 1.4e-62 XP_011539371 (OMIM: 612257) PREDICTED: microtubule (1397) 3587 238.0 3.5e-61 XP_016881990 (OMIM: 612256) PREDICTED: microtubule (1169) 1998 140.0 9.5e-32 XP_011526110 (OMIM: 612256) PREDICTED: microtubule (1126) 1668 119.6 1.2e-25 NP_001275693 (OMIM: 160900,605377) myotonin-protei ( 655) 728 61.4 2.4e-08 XP_011543458 (OMIM: 613991) PREDICTED: serine/thre (1562) 735 62.3 3.1e-08 XP_016873487 (OMIM: 613991) PREDICTED: serine/thre (1081) 728 61.7 3.3e-08 XP_011543463 (OMIM: 613991) PREDICTED: serine/thre (1135) 728 61.7 3.4e-08 XP_016873486 (OMIM: 613991) PREDICTED: serine/thre (1139) 728 61.7 3.4e-08 >>NP_055831 (OMIM: 612258) microtubule-associated serine (1309 aa) initn: 8735 init1: 8735 opt: 8735 Z-score: 2934.8 bits: 555.3 E(85289): 9.8e-157 Smith-Waterman score: 8735; 100.0% identity (100.0% similar) in 1309 aa overlap (1-1309:1-1309) 10 20 30 40 50 60 pF1KA0 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPFQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPFQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 TPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLVTSRYFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLVTSRYFL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRALVGQSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRALVGQSRR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 KPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 CGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 AEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 TFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPSPSLLNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPSPSLLNT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 ISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 ARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVPKSASVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVPKSASVS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 ALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKY 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 GFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 ELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKKIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKKIS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 SPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPISAPPPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPISAPPPR 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 SPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRLHLSERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRLHLSERR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KA0 DSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD ::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD 1270 1280 1290 1300 >>XP_005259884 (OMIM: 612258) PREDICTED: microtubule-ass (1315 aa) initn: 8592 init1: 8592 opt: 8592 Z-score: 2887.2 bits: 546.5 E(85289): 4.4e-154 Smith-Waterman score: 8592; 99.5% identity (99.9% similar) in 1293 aa overlap (17-1309:23-1315) 10 20 30 40 50 pF1KA0 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTA .: .:...:::::::::::::::::::::::::::::: XP_005 MSDPSYWTAVAAPGHRSRLAKGALLQRSKSCRSGNRKSLVVGTPSPTLSRPLSPLSVPTA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 GSSPLDSPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSSPLDSPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 QLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 VYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 TSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFY 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 HLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRAL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 VGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFV 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 ERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAET 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 VLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDARE 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 FIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA0 DEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA0 FVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFL 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA0 AVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPS 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA0 PSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSAD 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA0 TAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA0 KSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIH 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KA0 SSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGL 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KA0 VHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKS 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KA0 LFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTT 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KA0 ASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPI 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KA0 SAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRL 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 pF1KA0 HLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD 1270 1280 1290 1300 1310 >>XP_016881999 (OMIM: 612258) PREDICTED: microtubule-ass (1403 aa) initn: 8583 init1: 8583 opt: 8583 Z-score: 2883.9 bits: 546.0 E(85289): 6.8e-154 Smith-Waterman score: 8583; 99.8% identity (99.9% similar) in 1288 aa overlap (22-1309:116-1403) 10 20 30 40 50 pF1KA0 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSV : .::::::::::::::::::::::::::: XP_016 RARVRHRHPQTVGFALRGRKDRAGGAWCWWGCSCRSGNRKSLVVGTPSPTLSRPLSPLSV 90 100 110 120 130 140 60 70 80 90 100 110 pF1KA0 PTAGSSPLDSPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTAGSSPLDSPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRE 150 160 170 180 190 200 120 130 140 150 160 170 pF1KA0 RLHQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLHQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVM 210 220 230 240 250 260 180 190 200 210 220 230 pF1KA0 MNHVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNHVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGE 270 280 290 300 310 320 240 250 260 270 280 290 pF1KA0 NLVTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLVTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPE 330 340 350 360 370 380 300 310 320 330 340 350 pF1KA0 EFYHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFYHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPES 390 400 410 420 430 440 360 370 380 390 400 410 pF1KA0 RALVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RALVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQ 450 460 470 480 490 500 420 430 440 450 460 470 pF1KA0 VFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYF 510 520 530 540 550 560 480 490 500 510 520 530 pF1KA0 AETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKD 570 580 590 600 610 620 540 550 560 570 580 590 pF1KA0 AREFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AREFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQ 630 640 650 660 670 680 600 610 620 630 640 650 pF1KA0 VVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRH 690 700 710 720 730 740 660 670 680 690 700 710 pF1KA0 KAEFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAEFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSS 750 760 770 780 790 800 720 730 740 750 760 770 pF1KA0 EFLAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFLAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPER 810 820 830 840 850 860 780 790 800 810 820 830 pF1KA0 GPSPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPSPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSL 870 880 890 900 910 920 840 850 860 870 880 890 pF1KA0 SADTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SADTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGG 930 940 950 960 970 980 900 910 920 930 940 950 pF1KA0 RVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPI 990 1000 1010 1020 1030 1040 960 970 980 990 1000 1010 pF1KA0 VIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESV 1050 1060 1070 1080 1090 1100 1020 1030 1040 1050 1060 1070 pF1KA0 LGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDR 1110 1120 1130 1140 1150 1160 1080 1090 1100 1110 1120 1130 pF1KA0 RKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPA 1170 1180 1190 1200 1210 1220 1140 1150 1160 1170 1180 1190 pF1KA0 DTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLAC 1230 1240 1250 1260 1270 1280 1200 1210 1220 1230 1240 1250 pF1KA0 PPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVM 1290 1300 1310 1320 1330 1340 1260 1270 1280 1290 1300 pF1KA0 RRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD 1350 1360 1370 1380 1390 1400 >>XP_006722763 (OMIM: 612258) PREDICTED: microtubule-ass (1314 aa) initn: 8381 init1: 8381 opt: 8575 Z-score: 2881.5 bits: 545.5 E(85289): 9.2e-154 Smith-Waterman score: 8575; 99.5% identity (99.8% similar) in 1293 aa overlap (17-1309:23-1314) 10 20 30 40 50 pF1KA0 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTA .: .:...::::::::::::::::::::::::::::: XP_006 MSDPSYWTAVAAPGHRSRLAKGALLQRSKSCRSGNRKSLVVGTPSPTLSRPLSPLSVPT- 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 GSSPLDSPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSSPLDSPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 QLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNH 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 VYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 TSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA0 HLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRAL 300 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 VGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFV 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 ERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAET 420 430 440 450 460 470 480 490 500 510 520 530 pF1KA0 VLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDARE 480 490 500 510 520 530 540 550 560 570 580 590 pF1KA0 FIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVS 540 550 560 570 580 590 600 610 620 630 640 650 pF1KA0 DEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAE 600 610 620 630 640 650 660 670 680 690 700 710 pF1KA0 FVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFL 660 670 680 690 700 710 720 730 740 750 760 770 pF1KA0 AVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPS 720 730 740 750 760 770 780 790 800 810 820 830 pF1KA0 PSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSAD 780 790 800 810 820 830 840 850 860 870 880 890 pF1KA0 TAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVP 840 850 860 870 880 890 900 910 920 930 940 950 pF1KA0 KSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIH 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA0 SSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGL 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KA0 VHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKS 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KA0 LFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTT 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KA0 ASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPI 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 pF1KA0 SAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRL 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KA0 HLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD 1260 1270 1280 1290 1300 1310 >>XP_016881998 (OMIM: 612258) PREDICTED: microtubule-ass (1410 aa) initn: 8569 init1: 8228 opt: 8559 Z-score: 2875.8 bits: 544.5 E(85289): 1.9e-153 Smith-Waterman score: 8559; 99.3% identity (99.4% similar) in 1295 aa overlap (22-1309:116-1410) 10 20 30 40 50 pF1KA0 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSV : .::::::::::::::::::::::::::: XP_016 RARVRHRHPQTVGFALRGRKDRAGGAWCWWGCSCRSGNRKSLVVGTPSPTLSRPLSPLSV 90 100 110 120 130 140 60 70 80 90 100 pF1KA0 PTAGSSPLDSPRNFSAASALNFPFAR-------RADGRRWSLASLPSSGYGTNTPSSTLS :::::::::::::::::::::::::: ::::::::::::::::::::::::::: XP_016 PTAGSSPLDSPRNFSAASALNFPFARSHIPRMDRADGRRWSLASLPSSGYGTNTPSSTLS 150 160 170 180 190 200 110 120 130 140 150 160 pF1KA0 SSSSSRERLHQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSSSRERLHQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGT 210 220 230 240 250 260 170 180 190 200 210 220 pF1KA0 FDNEIVMMNHVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDNEIVMMNHVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARD 270 280 290 300 310 320 230 240 250 260 270 280 pF1KA0 CLAKSGENLVTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLAKSGENLVTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLE 330 340 350 360 370 380 290 300 310 320 330 340 pF1KA0 CLEFDPEEFYHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLEFDPEEFYHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPP 390 400 410 420 430 440 350 360 370 380 390 400 pF1KA0 APESPESRALVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APESPESRALVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLI 450 460 470 480 490 500 410 420 430 440 450 460 pF1KA0 LRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPV 510 520 530 540 550 560 470 480 490 500 510 520 pF1KA0 DMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLY 570 580 590 600 610 620 530 540 550 560 570 580 pF1KA0 EGHIEKDAREFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGHIEKDAREFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDT 630 640 650 660 670 680 590 600 610 620 630 640 pF1KA0 PEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALD 690 700 710 720 730 740 650 660 670 680 690 700 pF1KA0 WAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRF 750 760 770 780 790 800 710 720 730 740 750 760 pF1KA0 SKVYSSSEFLAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKVYSSSEFLAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQS 810 820 830 840 850 860 770 780 790 800 810 820 pF1KA0 SSSQPERGPSPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSQPERGPSPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPV 870 880 890 900 910 920 830 840 850 860 870 880 pF1KA0 MPKPSSLSADTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPKPSSLSADTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGG 930 940 950 960 970 980 890 900 910 920 930 940 pF1KA0 SGGGSGGRVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGGGSGGRVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVC 990 1000 1010 1020 1030 1040 950 960 970 980 990 1000 pF1KA0 GSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLIT 1050 1060 1070 1080 1090 1100 1010 1020 1030 1040 1050 1060 pF1KA0 HINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSR 1110 1120 1130 1140 1150 1160 1070 1080 1090 1100 1110 1120 pF1KA0 RRETQDRRKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRETQDRRKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRS 1170 1180 1190 1200 1210 1220 1130 1140 1150 1160 1170 1180 pF1KA0 PAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSI 1230 1240 1250 1260 1270 1280 1190 1200 1210 1220 1230 1240 pF1KA0 PPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGP 1290 1300 1310 1320 1330 1340 1250 1260 1270 1280 1290 1300 pF1KA0 EAELVVMRRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAELVVMRRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALG 1350 1360 1370 1380 1390 1400 pF1KA0 PTGRD ::::: XP_016 PTGRD 1410 >>XP_016882005 (OMIM: 612258) PREDICTED: microtubule-ass (1409 aa) initn: 8416 init1: 8228 opt: 8542 Z-score: 2870.2 bits: 543.5 E(85289): 3.9e-153 Smith-Waterman score: 8542; 99.2% identity (99.3% similar) in 1295 aa overlap (22-1309:116-1409) 10 20 30 40 50 pF1KA0 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSV : .::::::::::::::::::::::::::: XP_016 RARVRHRHPQTVGFALRGRKDRAGGAWCWWGCSCRSGNRKSLVVGTPSPTLSRPLSPLSV 90 100 110 120 130 140 60 70 80 90 100 pF1KA0 PTAGSSPLDSPRNFSAASALNFPFAR-------RADGRRWSLASLPSSGYGTNTPSSTLS :: ::::::::::::::::::::::: ::::::::::::::::::::::::::: XP_016 PT-GSSPLDSPRNFSAASALNFPFARSHIPRMDRADGRRWSLASLPSSGYGTNTPSSTLS 150 160 170 180 190 200 110 120 130 140 150 160 pF1KA0 SSSSSRERLHQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSSSRERLHQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGT 210 220 230 240 250 260 170 180 190 200 210 220 pF1KA0 FDNEIVMMNHVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDNEIVMMNHVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARD 270 280 290 300 310 320 230 240 250 260 270 280 pF1KA0 CLAKSGENLVTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLAKSGENLVTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLE 330 340 350 360 370 380 290 300 310 320 330 340 pF1KA0 CLEFDPEEFYHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLEFDPEEFYHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPP 390 400 410 420 430 440 350 360 370 380 390 400 pF1KA0 APESPESRALVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APESPESRALVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLI 450 460 470 480 490 500 410 420 430 440 450 460 pF1KA0 LRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPV 510 520 530 540 550 560 470 480 490 500 510 520 pF1KA0 DMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLY 570 580 590 600 610 620 530 540 550 560 570 580 pF1KA0 EGHIEKDAREFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGHIEKDAREFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDT 630 640 650 660 670 680 590 600 610 620 630 640 pF1KA0 PEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALD 690 700 710 720 730 740 650 660 670 680 690 700 pF1KA0 WAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRF 750 760 770 780 790 800 710 720 730 740 750 760 pF1KA0 SKVYSSSEFLAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKVYSSSEFLAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQS 810 820 830 840 850 860 770 780 790 800 810 820 pF1KA0 SSSQPERGPSPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSQPERGPSPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPV 870 880 890 900 910 920 830 840 850 860 870 880 pF1KA0 MPKPSSLSADTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPKPSSLSADTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGG 930 940 950 960 970 980 890 900 910 920 930 940 pF1KA0 SGGGSGGRVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGGGSGGRVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVC 990 1000 1010 1020 1030 1040 950 960 970 980 990 1000 pF1KA0 GSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLIT 1050 1060 1070 1080 1090 1100 1010 1020 1030 1040 1050 1060 pF1KA0 HINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSR 1110 1120 1130 1140 1150 1160 1070 1080 1090 1100 1110 1120 pF1KA0 RRETQDRRKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRETQDRRKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRS 1170 1180 1190 1200 1210 1220 1130 1140 1150 1160 1170 1180 pF1KA0 PAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSI 1230 1240 1250 1260 1270 1280 1190 1200 1210 1220 1230 1240 pF1KA0 PPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGP 1290 1300 1310 1320 1330 1340 1250 1260 1270 1280 1290 1300 pF1KA0 EAELVVMRRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAELVVMRRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALG 1350 1360 1370 1380 1390 1400 pF1KA0 PTGRD ::::: XP_016 PTGRD >>XP_016882001 (OMIM: 612258) PREDICTED: microtubule-ass (1318 aa) initn: 7240 init1: 7169 opt: 7275 Z-score: 2448.4 bits: 465.3 E(85289): 1.2e-129 Smith-Waterman score: 8707; 99.3% identity (99.3% similar) in 1318 aa overlap (1-1309:1-1318) 10 20 30 40 50 60 pF1KA0 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPFQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPFQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 TPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLVTSRYFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLVTSRYFL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRALVGQSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRALVGQSRR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 KPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 CGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 AEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 TFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPSPSLLNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPSPSLLNT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 ISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 ARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVPKSASVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVPKSASVS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 ALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKY 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 GFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KA0 ELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDR--------- ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRCAAVTTRER 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KA0 RKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPA 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KA0 DTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLAC 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KA0 PPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVM 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 pF1KA0 RRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD 1270 1280 1290 1300 1310 >>XP_016882002 (OMIM: 612258) PREDICTED: microtubule-ass (1317 aa) initn: 6886 init1: 6815 opt: 7258 Z-score: 2442.8 bits: 464.3 E(85289): 2.5e-129 Smith-Waterman score: 8690; 99.2% identity (99.2% similar) in 1318 aa overlap (1-1309:1-1317) 10 20 30 40 50 60 pF1KA0 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLD ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_016 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPT-GSSPLD 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 SPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPFQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPFQP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 TPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 PKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLVTSRYFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLVTSRYFL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 EMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAA 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 EGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRALVGQSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRALVGQSRR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 KPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILT 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA0 FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEY 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA0 LHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQV 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 CGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 EGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLE 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA0 AEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTP 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA0 TFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPSPSLLNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPSPSLLNT 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA0 ISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSH 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 ARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVPKSASVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVPKSASVS 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA0 ALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKY 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA0 GFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVV 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 pF1KA0 ELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDR--------- ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRCAAVTTRER 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KA0 RKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPA 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KA0 DTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLAC 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 pF1KA0 PPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVM 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KA0 RRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD 1260 1270 1280 1290 1300 1310 >>XP_005259881 (OMIM: 612258) PREDICTED: microtubule-ass (1325 aa) initn: 7226 init1: 6662 opt: 7251 Z-score: 2440.4 bits: 463.9 E(85289): 3.4e-129 Smith-Waterman score: 8683; 98.8% identity (98.8% similar) in 1325 aa overlap (1-1309:1-1325) 10 20 30 40 50 60 pF1KA0 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLD 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 SPRNFSAASALNFPFAR-------RADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERL ::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_005 SPRNFSAASALNFPFARSHIPRMDRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 HQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMN 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 HVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 VTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEF 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 YHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 LVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVF 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 VERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAE 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 TVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAR 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 EFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA0 SDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKA 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA0 EFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEF 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA0 LAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA0 SPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSA 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA0 DTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRV 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA0 PKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVI 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KA0 HSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLG 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KA0 LVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDR-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRCA 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 pF1KA0 -------RKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVTTRERRKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRS 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA0 PAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSI 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA0 PPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGP 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA0 EAELVVMRRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAELVVMRRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALG 1270 1280 1290 1300 1310 1320 pF1KA0 PTGRD ::::: XP_005 PTGRD >>XP_005259882 (OMIM: 612258) PREDICTED: microtubule-ass (1324 aa) initn: 7073 init1: 6662 opt: 7234 Z-score: 2434.7 bits: 462.8 E(85289): 7.1e-129 Smith-Waterman score: 8666; 98.7% identity (98.7% similar) in 1325 aa overlap (1-1309:1-1324) 10 20 30 40 50 60 pF1KA0 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLD ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_005 MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPT-GSSPLD 10 20 30 40 50 70 80 90 100 110 pF1KA0 SPRNFSAASALNFPFAR-------RADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERL ::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_005 SPRNFSAASALNFPFARSHIPRMDRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 HQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 HVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 VTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEF 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA0 YHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRA 300 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 LVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVF 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 VERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAE 420 430 440 450 460 470 480 490 500 510 520 530 pF1KA0 TVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAR 480 490 500 510 520 530 540 550 560 570 580 590 pF1KA0 EFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVV 540 550 560 570 580 590 600 610 620 630 640 650 pF1KA0 SDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKA 600 610 620 630 640 650 660 670 680 690 700 710 pF1KA0 EFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEF 660 670 680 690 700 710 720 730 740 750 760 770 pF1KA0 LAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGP 720 730 740 750 760 770 780 790 800 810 820 830 pF1KA0 SPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSA 780 790 800 810 820 830 840 850 860 870 880 890 pF1KA0 DTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRV 840 850 860 870 880 890 900 910 920 930 940 950 pF1KA0 PKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVI 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA0 HSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLG 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KA0 LVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDR-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRCA 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 pF1KA0 -------RKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVTTRERRKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRS 1080 1090 1100 1110 1120 1130 1130 1140 1150 1160 1170 1180 pF1KA0 PAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSI 1140 1150 1160 1170 1180 1190 1190 1200 1210 1220 1230 1240 pF1KA0 PPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGP 1200 1210 1220 1230 1240 1250 1250 1260 1270 1280 1290 1300 pF1KA0 EAELVVMRRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAELVVMRRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALG 1260 1270 1280 1290 1300 1310 pF1KA0 PTGRD ::::: XP_005 PTGRD 1320 1309 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:42:44 2016 done: Sat Nov 5 06:42:47 2016 Total Scan time: 19.540 Total Display time: 0.700 Function used was FASTA [36.3.4 Apr, 2011]