FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0562, 925 aa 1>>>pF1KA0562 925 - 925 aa - 925 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3991+/-0.00044; mu= 12.8176+/- 0.028 mean_var=151.4429+/-31.560, 0's: 0 Z-trim(115.7): 15 B-trim: 1435 in 1/51 Lambda= 0.104220 statistics sampled from 26265 (26280) to 26265 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.308), width: 16 Scan time: 12.230 The best scores are: opt bits E(85289) NP_055519 (OMIM: 616690,616781) centrosomal protei ( 925) 6118 932.6 0 XP_005244872 (OMIM: 616690,616781) PREDICTED: cent ( 961) 6118 932.6 0 XP_011540776 (OMIM: 616690,616781) PREDICTED: cent ( 931) 6096 929.3 0 XP_011540775 (OMIM: 616690,616781) PREDICTED: cent ( 967) 6096 929.3 0 XP_011540780 (OMIM: 616690,616781) PREDICTED: cent ( 777) 4633 709.3 1.9e-203 XP_016858407 (OMIM: 616690,616781) PREDICTED: cent ( 867) 3754 577.1 1.3e-163 XP_016858406 (OMIM: 616690,616781) PREDICTED: cent ( 903) 3754 577.1 1.3e-163 XP_011540777 (OMIM: 616690,616781) PREDICTED: cent ( 909) 3754 577.1 1.3e-163 XP_016858408 (OMIM: 616690,616781) PREDICTED: cent ( 859) 3199 493.7 1.7e-138 XP_011540778 (OMIM: 616690,616781) PREDICTED: cent ( 901) 3199 493.7 1.7e-138 XP_011540779 (OMIM: 616690,616781) PREDICTED: cent ( 843) 3191 492.5 3.8e-138 >>NP_055519 (OMIM: 616690,616781) centrosomal protein of (925 aa) initn: 6118 init1: 6118 opt: 6118 Z-score: 4979.2 bits: 932.6 E(85289): 0 Smith-Waterman score: 6118; 100.0% identity (100.0% similar) in 925 aa overlap (1-925:1-925) 10 20 30 40 50 60 pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 TEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG 850 860 870 880 890 900 910 920 pF1KA0 SKAGSKIPTPKGGLSKSSSRTYAKR ::::::::::::::::::::::::: NP_055 SKAGSKIPTPKGGLSKSSSRTYAKR 910 920 >>XP_005244872 (OMIM: 616690,616781) PREDICTED: centroso (961 aa) initn: 6118 init1: 6118 opt: 6118 Z-score: 4978.9 bits: 932.6 E(85289): 0 Smith-Waterman score: 6118; 100.0% identity (100.0% similar) in 925 aa overlap (1-925:37-961) 10 20 30 pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPT :::::::::::::::::::::::::::::: XP_005 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 RFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINI 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 IGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEV 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 AQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAK 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 EKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSLPQLEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSLPQLEER 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA0 GTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPLPAIRKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPLPAIRKH 370 380 390 400 410 420 400 410 420 430 440 450 pF1KA0 YGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSY 430 440 450 460 470 480 460 470 480 490 500 510 pF1KA0 REDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 REDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQ 490 500 510 520 530 540 520 530 540 550 560 570 pF1KA0 YIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSY 550 560 570 580 590 600 580 590 600 610 620 630 pF1KA0 LVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAV 610 620 630 640 650 660 640 650 660 670 680 690 pF1KA0 RIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEE 670 680 690 700 710 720 700 710 720 730 740 750 pF1KA0 AEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYL 730 740 750 760 770 780 760 770 780 790 800 810 pF1KA0 DNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFG 790 800 810 820 830 840 820 830 840 850 860 870 pF1KA0 KCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCT 850 860 870 880 890 900 880 890 900 910 920 pF1KA0 MNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR 910 920 930 940 950 960 >>XP_011540776 (OMIM: 616690,616781) PREDICTED: centroso (931 aa) initn: 5463 init1: 5463 opt: 6096 Z-score: 4961.3 bits: 929.3 E(85289): 0 Smith-Waterman score: 6096; 99.4% identity (99.4% similar) in 931 aa overlap (1-925:1-931) 10 20 30 40 50 60 pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLG------YVSLCDNEKTGCKARELK :::::::::::::::::::::::::::::::::::: :::::::::::::::::: XP_011 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGCVLFFSYVSLCDNEKTGCKARELK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 SVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 GHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 KLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLD 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 AELMRRPFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AELMRRPFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 QHSAVDPLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QHSAVDPLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGML 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 GEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 KNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 TRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARL 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA0 LKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSN 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA0 TRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA0 EVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYW 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA0 KHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCN 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA0 PAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVA 850 860 870 880 890 900 900 910 920 pF1KA0 ASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR ::::::::::::::::::::::::::::::: XP_011 ASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR 910 920 930 >>XP_011540775 (OMIM: 616690,616781) PREDICTED: centroso (967 aa) initn: 5463 init1: 5463 opt: 6096 Z-score: 4961.0 bits: 929.3 E(85289): 0 Smith-Waterman score: 6096; 99.4% identity (99.4% similar) in 931 aa overlap (1-925:37-967) 10 20 30 pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPT :::::::::::::::::::::::::::::: XP_011 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE 70 80 90 100 110 120 100 110 120 130 140 pF1KA0 RFRRLG------YVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA :::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFRRLGCVLFFSYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA 130 140 150 160 170 180 150 160 170 180 190 200 pF1KA0 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM 190 200 210 220 230 240 210 220 230 240 250 260 pF1KA0 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE 250 260 270 280 290 300 270 280 290 300 310 320 pF1KA0 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL 310 320 330 340 350 360 330 340 350 360 370 380 pF1KA0 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL 370 380 390 400 410 420 390 400 410 420 430 440 pF1KA0 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY 430 440 450 460 470 480 450 460 470 480 490 500 pF1KA0 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL 490 500 510 520 530 540 510 520 530 540 550 560 pF1KA0 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL 550 560 570 580 590 600 570 580 590 600 610 620 pF1KA0 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE 610 620 630 640 650 660 630 640 650 660 670 680 pF1KA0 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR 670 680 690 700 710 720 690 700 710 720 730 740 pF1KA0 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI 730 740 750 760 770 780 750 760 770 780 790 800 pF1KA0 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD 790 800 810 820 830 840 810 820 830 840 850 860 pF1KA0 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM 850 860 870 880 890 900 870 880 890 900 910 920 pF1KA0 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK 910 920 930 940 950 960 pF1KA0 R : XP_011 R >>XP_011540780 (OMIM: 616690,616781) PREDICTED: centroso (777 aa) initn: 4000 init1: 4000 opt: 4633 Z-score: 3773.5 bits: 709.3 E(85289): 1.9e-203 Smith-Waterman score: 4633; 99.2% identity (99.2% similar) in 723 aa overlap (1-717:37-759) 10 20 30 pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPT :::::::::::::::::::::::::::::: XP_011 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE 70 80 90 100 110 120 100 110 120 130 140 pF1KA0 RFRRLG------YVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA :::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFRRLGCVLFFSYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA 130 140 150 160 170 180 150 160 170 180 190 200 pF1KA0 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM 190 200 210 220 230 240 210 220 230 240 250 260 pF1KA0 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE 250 260 270 280 290 300 270 280 290 300 310 320 pF1KA0 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL 310 320 330 340 350 360 330 340 350 360 370 380 pF1KA0 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL 370 380 390 400 410 420 390 400 410 420 430 440 pF1KA0 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY 430 440 450 460 470 480 450 460 470 480 490 500 pF1KA0 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL 490 500 510 520 530 540 510 520 530 540 550 560 pF1KA0 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL 550 560 570 580 590 600 570 580 590 600 610 620 pF1KA0 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE 610 620 630 640 650 660 630 640 650 660 670 680 pF1KA0 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR 670 680 690 700 710 720 690 700 710 720 730 740 pF1KA0 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI ::::::::::::::::::::::::::::::::: XP_011 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQLSSHLQRQRRKISLTIKV 730 740 750 760 770 750 760 770 780 790 800 pF1KA0 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD >>XP_016858407 (OMIM: 616690,616781) PREDICTED: centroso (867 aa) initn: 3751 init1: 3751 opt: 3754 Z-score: 3058.6 bits: 577.1 E(85289): 1.3e-163 Smith-Waterman score: 5585; 93.7% identity (93.7% similar) in 925 aa overlap (1-925:1-867) 10 20 30 40 50 60 pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAEL--- 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 PFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVD ::::: XP_016 -------------------------------------------------------HSAVD 300 370 380 390 400 410 420 pF1KA0 PLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPL 310 320 330 340 350 360 430 440 450 460 470 480 pF1KA0 TEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA 370 380 390 400 410 420 490 500 510 520 530 540 pF1KA0 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS 430 440 450 460 470 480 550 560 570 580 590 600 pF1KA0 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT 490 500 510 520 530 540 610 620 630 640 650 660 pF1KA0 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL 550 560 570 580 590 600 670 680 690 700 710 720 pF1KA0 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE 610 620 630 640 650 660 730 740 750 760 770 780 pF1KA0 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML 670 680 690 700 710 720 790 800 810 820 830 840 pF1KA0 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK 730 740 750 760 770 780 850 860 870 880 890 900 pF1KA0 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG 790 800 810 820 830 840 910 920 pF1KA0 SKAGSKIPTPKGGLSKSSSRTYAKR ::::::::::::::::::::::::: XP_016 SKAGSKIPTPKGGLSKSSSRTYAKR 850 860 >>XP_016858406 (OMIM: 616690,616781) PREDICTED: centroso (903 aa) initn: 3751 init1: 3751 opt: 3754 Z-score: 3058.3 bits: 577.1 E(85289): 1.3e-163 Smith-Waterman score: 5585; 93.7% identity (93.7% similar) in 925 aa overlap (1-925:37-903) 10 20 30 pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPT :::::::::::::::::::::::::::::: XP_016 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 RFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINI 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 IGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEV 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 AQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAK 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 EKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSLPQLEER ::::::::::::::::::::::::::: XP_016 EKKQQMEQYRAEVYEQLELHSLLDAEL--------------------------------- 310 320 330 340 350 360 370 380 390 pF1KA0 GTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPLPAIRKH ::::::::::::::::::::::::::::::::::: XP_016 -------------------------HSAVDPLLPATDPHPKINAESLPYDERPLPAIRKH 340 350 360 400 410 420 430 440 450 pF1KA0 YGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSY 370 380 390 400 410 420 460 470 480 490 500 510 pF1KA0 REDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQ 430 440 450 460 470 480 520 530 540 550 560 570 pF1KA0 YIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSY 490 500 510 520 530 540 580 590 600 610 620 630 pF1KA0 LVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAV 550 560 570 580 590 600 640 650 660 670 680 690 pF1KA0 RIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEE 610 620 630 640 650 660 700 710 720 730 740 750 pF1KA0 AEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYL 670 680 690 700 710 720 760 770 780 790 800 810 pF1KA0 DNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFG 730 740 750 760 770 780 820 830 840 850 860 870 pF1KA0 KCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCT 790 800 810 820 830 840 880 890 900 910 920 pF1KA0 MNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR 850 860 870 880 890 900 >>XP_011540777 (OMIM: 616690,616781) PREDICTED: centroso (909 aa) initn: 4452 init1: 3751 opt: 3754 Z-score: 3058.3 bits: 577.1 E(85289): 1.3e-163 Smith-Waterman score: 5563; 93.1% identity (93.1% similar) in 931 aa overlap (1-925:37-909) 10 20 30 pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPT :::::::::::::::::::::::::::::: XP_011 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE 70 80 90 100 110 120 100 110 120 130 140 pF1KA0 RFRRLG------YVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA :::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFRRLGCVLFFSYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA 130 140 150 160 170 180 150 160 170 180 190 200 pF1KA0 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM 190 200 210 220 230 240 210 220 230 240 250 260 pF1KA0 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE 250 260 270 280 290 300 270 280 290 300 310 320 pF1KA0 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL ::::::::::::::::::::::::::::::::: XP_011 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAEL--------------------------- 310 320 330 330 340 350 360 370 380 pF1KA0 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL ::::::::::::::::::::::::::::: XP_011 -------------------------------HSAVDPLLPATDPHPKINAESLPYDERPL 340 350 360 390 400 410 420 430 440 pF1KA0 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY 370 380 390 400 410 420 450 460 470 480 490 500 pF1KA0 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL 430 440 450 460 470 480 510 520 530 540 550 560 pF1KA0 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL 490 500 510 520 530 540 570 580 590 600 610 620 pF1KA0 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE 550 560 570 580 590 600 630 640 650 660 670 680 pF1KA0 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR 610 620 630 640 650 660 690 700 710 720 730 740 pF1KA0 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI 670 680 690 700 710 720 750 760 770 780 790 800 pF1KA0 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD 730 740 750 760 770 780 810 820 830 840 850 860 pF1KA0 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM 790 800 810 820 830 840 870 880 890 900 910 920 pF1KA0 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK 850 860 870 880 890 900 pF1KA0 R : XP_011 R >>XP_016858408 (OMIM: 616690,616781) PREDICTED: centroso (859 aa) initn: 5678 init1: 3191 opt: 3199 Z-score: 2607.6 bits: 493.7 E(85289): 1.7e-138 Smith-Waterman score: 5550; 92.9% identity (92.9% similar) in 925 aa overlap (1-925:1-859) 10 20 30 40 50 60 pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPL ::::::::::::: XP_016 PLLPATDPHPKIN----------------------------------------------- 370 430 440 450 460 470 480 pF1KA0 TEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA ::::::::::::::::::::::::::::::::::::::::: XP_016 -------------------VAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA 380 390 400 410 490 500 510 520 530 540 pF1KA0 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS 420 430 440 450 460 470 550 560 570 580 590 600 pF1KA0 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT 480 490 500 510 520 530 610 620 630 640 650 660 pF1KA0 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL 540 550 560 570 580 590 670 680 690 700 710 720 pF1KA0 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE 600 610 620 630 640 650 730 740 750 760 770 780 pF1KA0 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML 660 670 680 690 700 710 790 800 810 820 830 840 pF1KA0 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK 720 730 740 750 760 770 850 860 870 880 890 900 pF1KA0 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG 780 790 800 810 820 830 910 920 pF1KA0 SKAGSKIPTPKGGLSKSSSRTYAKR ::::::::::::::::::::::::: XP_016 SKAGSKIPTPKGGLSKSSSRTYAKR 840 850 >>XP_011540778 (OMIM: 616690,616781) PREDICTED: centroso (901 aa) initn: 5023 init1: 3191 opt: 3199 Z-score: 2607.4 bits: 493.7 E(85289): 1.7e-138 Smith-Waterman score: 5528; 92.3% identity (92.3% similar) in 931 aa overlap (1-925:37-901) 10 20 30 pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPT :::::::::::::::::::::::::::::: XP_011 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE 70 80 90 100 110 120 100 110 120 130 140 pF1KA0 RFRRLG------YVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA :::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFRRLGCVLFFSYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA 130 140 150 160 170 180 150 160 170 180 190 200 pF1KA0 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM 190 200 210 220 230 240 210 220 230 240 250 260 pF1KA0 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE 250 260 270 280 290 300 270 280 290 300 310 320 pF1KA0 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL 310 320 330 340 350 360 330 340 350 360 370 380 pF1KA0 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKIN----------- 370 380 390 400 410 390 400 410 420 430 440 pF1KA0 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY ::::: XP_011 -------------------------------------------------------VAEAY 420 450 460 470 480 490 500 pF1KA0 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL 430 440 450 460 470 480 510 520 530 540 550 560 pF1KA0 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL 490 500 510 520 530 540 570 580 590 600 610 620 pF1KA0 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE 550 560 570 580 590 600 630 640 650 660 670 680 pF1KA0 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR 610 620 630 640 650 660 690 700 710 720 730 740 pF1KA0 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI 670 680 690 700 710 720 750 760 770 780 790 800 pF1KA0 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD 730 740 750 760 770 780 810 820 830 840 850 860 pF1KA0 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM 790 800 810 820 830 840 870 880 890 900 910 920 pF1KA0 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK 850 860 870 880 890 900 pF1KA0 R : XP_011 R 925 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:16:46 2016 done: Wed Nov 2 19:16:47 2016 Total Scan time: 12.230 Total Display time: 0.260 Function used was FASTA [36.3.4 Apr, 2011]