Result of FASTA (omim) for
pF1KA0563
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0563, 1634 aa
1>>>pF1KA0563 1634 - 1634 aa - 1634 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.4222+/-0.000565; mu= -26.3573+/- 0.035
mean_var=520.2650+/-114.478, 0's: 0 Z-trim(120.1): 179 B-trim: 2867 in 2/54
Lambda= 0.056229
statistics sampled from 34653 (34910) to 34653 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.409), width: 16
Scan time: 17.610
The best scores are: opt bits E(85289)
NP_955372 (OMIM: 616557) leucine-rich repeat-conta (1634) 10908 901.2 0
XP_016880082 (OMIM: 616557) PREDICTED: leucine-ric (1638) 10698 884.2 0
NP_001006608 (OMIM: 616556) leucine-rich repeat-co (1700) 10563 873.2 0
NP_055649 (OMIM: 616555) leucine-rich repeat-conta (1700) 10524 870.1 0
XP_011523144 (OMIM: 616556) PREDICTED: leucine-ric (1665) 10263 848.9 0
XP_005257936 (OMIM: 616555) PREDICTED: leucine-ric (1665) 10224 845.7 0
XP_016880088 (OMIM: 616557) PREDICTED: leucine-ric (1544) 9985 826.3 0
XP_016880961 (OMIM: 616555) PREDICTED: leucine-ric (1606) 9843 814.8 0
XP_005257939 (OMIM: 616555) PREDICTED: leucine-ric (1606) 9843 814.8 0
XP_016880089 (OMIM: 616557) PREDICTED: leucine-ric (1018) 6883 574.6 1.5e-162
XP_005257940 (OMIM: 616555) PREDICTED: leucine-ric (1018) 6804 568.2 1.3e-160
XP_011523151 (OMIM: 616556) PREDICTED: leucine-ric (1018) 6789 567.0 2.9e-160
XP_005257937 (OMIM: 616555) PREDICTED: leucine-ric (1651) 6507 544.2 3.4e-153
XP_005257941 (OMIM: 616555) PREDICTED: leucine-ric ( 969) 6493 543.0 4.8e-153
XP_011523145 (OMIM: 616556) PREDICTED: leucine-ric (1651) 6492 543.0 8e-153
XP_011523152 (OMIM: 616556) PREDICTED: leucine-ric ( 969) 6478 541.8 1.1e-152
XP_016880084 (OMIM: 616557) PREDICTED: leucine-ric (1610) 6280 525.8 1.2e-147
XP_016880083 (OMIM: 616557) PREDICTED: leucine-ric (1614) 6280 525.8 1.2e-147
XP_016880086 (OMIM: 616557) PREDICTED: leucine-ric (1583) 6268 524.8 2.3e-147
XP_016880085 (OMIM: 616557) PREDICTED: leucine-ric (1587) 6268 524.8 2.3e-147
XP_011523841 (OMIM: 616555) PREDICTED: leucine-ric (1649) 6189 518.4 2e-145
XP_011523143 (OMIM: 616556) PREDICTED: leucine-ric (1676) 6186 518.2 2.4e-145
XP_011523146 (OMIM: 616556) PREDICTED: leucine-ric (1649) 6174 517.2 4.7e-145
XP_006722273 (OMIM: 616555) PREDICTED: leucine-ric (1600) 6151 515.3 1.7e-144
XP_011523150 (OMIM: 616556) PREDICTED: leucine-ric (1600) 6136 514.1 3.9e-144
XP_016880087 (OMIM: 616557) PREDICTED: leucine-ric (1563) 6121 512.9 8.8e-144
XP_011523148 (OMIM: 616556) PREDICTED: leucine-ric (1625) 6027 505.3 1.8e-141
XP_006722274 (OMIM: 616555) PREDICTED: leucine-ric (1576) 6010 503.9 4.5e-141
XP_011523080 (OMIM: 616557) PREDICTED: leucine-ric ( 837) 5014 423.0 5.5e-117
XP_011523078 (OMIM: 616557) PREDICTED: leucine-ric ( 803) 5008 422.5 7.4e-117
XP_016880090 (OMIM: 616557) PREDICTED: leucine-ric ( 898) 5008 422.5 8.2e-117
XP_016880092 (OMIM: 616557) PREDICTED: leucine-ric ( 807) 4798 405.4 1e-111
XP_016880962 (OMIM: 616555) PREDICTED: leucine-ric ( 864) 4708 398.1 1.7e-109
XP_011523079 (OMIM: 616557) PREDICTED: leucine-ric ( 752) 4368 370.5 3e-101
NP_001290184 (OMIM: 616557) leucine-rich repeat-co ( 752) 4368 370.5 3e-101
XP_016880095 (OMIM: 616557) PREDICTED: leucine-ric ( 728) 4360 369.9 4.6e-101
XP_016880093 (OMIM: 616557) PREDICTED: leucine-ric ( 783) 4350 369.1 8.5e-101
XP_016880096 (OMIM: 616557) PREDICTED: leucine-ric ( 676) 4170 354.5 1.9e-96
XP_016880097 (OMIM: 616557) PREDICTED: leucine-ric ( 676) 4170 354.5 1.9e-96
XP_016880094 (OMIM: 616557) PREDICTED: leucine-ric ( 756) 4158 353.5 4e-96
XP_016880091 (OMIM: 616557) PREDICTED: leucine-ric ( 827) 4150 352.9 6.8e-96
NP_001308279 (OMIM: 616558) leucine-rich repeat-co ( 865) 2387 209.9 8e-53
NP_443120 (OMIM: 616558) leucine-rich repeat-conta ( 947) 2387 209.9 8.7e-53
NP_001290161 (OMIM: 208250,604283) proteoglycan 4 (1361) 406 49.3 0.00028
XP_016855492 (OMIM: 208250,604283) PREDICTED: prot (1270) 398 48.6 0.00042
NP_001121182 (OMIM: 208250,604283) proteoglycan 4 (1270) 398 48.6 0.00042
NP_001121181 (OMIM: 208250,604283) proteoglycan 4 (1311) 398 48.6 0.00043
XP_016855491 (OMIM: 208250,604283) PREDICTED: prot (1311) 398 48.6 0.00043
NP_001121180 (OMIM: 208250,604283) proteoglycan 4 (1363) 398 48.6 0.00044
NP_005798 (OMIM: 208250,604283) proteoglycan 4 iso (1404) 398 48.6 0.00046
>>NP_955372 (OMIM: 616557) leucine-rich repeat-containin (1634 aa)
initn: 10908 init1: 10908 opt: 10908 Z-score: 4800.8 bits: 901.2 E(85289): 0
Smith-Waterman score: 10908; 100.0% identity (100.0% similar) in 1634 aa overlap (1-1634:1-1634)
10 20 30 40 50 60
pF1KA0 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 TSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 FIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 PAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 PAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 VKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 VKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 HFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 HFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQS
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 EQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 EQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSR
1570 1580 1590 1600 1610 1620
1630
pF1KA0 DSEAPTEEESEALP
::::::::::::::
NP_955 DSEAPTEEESEALP
1630
>>XP_016880082 (OMIM: 616557) PREDICTED: leucine-rich re (1638 aa)
initn: 11354 init1: 10698 opt: 10698 Z-score: 4708.7 bits: 884.2 E(85289): 0
Smith-Waterman score: 10698; 99.9% identity (100.0% similar) in 1604 aa overlap (1-1604:1-1604)
10 20 30 40 50 60
pF1KA0 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 PAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 VKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 HFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQS
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 EQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSR
:::::::::::::::::::::::::::::::::::::::::::.
XP_016 EQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEVRTIINSGFQNAVLSLC
1570 1580 1590 1600 1610 1620
1630
pF1KA0 DSEAPTEEESEALP
XP_016 GFRAHKLKTKATFPPAAT
1630
>>NP_001006608 (OMIM: 616556) leucine-rich repeat-contai (1700 aa)
initn: 10563 init1: 10563 opt: 10563 Z-score: 4649.2 bits: 873.2 E(85289): 0
Smith-Waterman score: 10563; 97.5% identity (98.8% similar) in 1620 aa overlap (1-1620:1-1620)
10 20 30 40 50 60
pF1KA0 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
:.:::::::.:::: ::::::::::::::::::::::::::::::::::::::::::. :
NP_001 MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL
:::::::::::::::::::::::::::::::::::::::::::::: .::::::::::::
NP_001 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_001 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
::::::::::::::::::::::::::: ::::::::::::::: ::::::::::::::::
NP_001 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLP
::::::.:::::::::::::::::::::::::::: :::::::::::::::::::::::
NP_001 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT
::::::::::::::::::.::::..::::::::::::::::::::::::::::::::::.
NP_001 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
:::::::::::::..:::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 PAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPK
::::::::::::::::::::::::::::::: ::::::::.:::::::::::..::::::
NP_001 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 VKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSE
::::::::::::::::::.::::::::::::::::::::::: :::::::::::::::::
NP_001 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 HFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
::::::::: :::::::::: ::::::::::::::::::::: :::::::::::::::::
NP_001 HFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_001 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQS
:::::::::::::::::.::::::::::::::::::::::::::::: ::::::::::::
NP_001 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 EQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSR
::::::::. ::.:::::: ::::::::::::::::::.::: :::::::::::::::::
NP_001 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
1570 1580 1590 1600 1610 1620
1630
pF1KA0 DSEAPTEEESEALP
NP_001 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKIL
1630 1640 1650 1660 1670 1680
>>NP_055649 (OMIM: 616555) leucine-rich repeat-containin (1700 aa)
initn: 10524 init1: 10524 opt: 10524 Z-score: 4632.1 bits: 870.1 E(85289): 0
Smith-Waterman score: 10524; 97.3% identity (98.7% similar) in 1620 aa overlap (1-1620:1-1620)
10 20 30 40 50 60
pF1KA0 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
:.:::::::.:::: ::::::::::::::::::::::::::::::::::::::::::: :
NP_055 MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_055 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL
:::::::::::::::::::::::::::::::::::::::::::::: .::::::::::::
NP_055 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_055 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
NP_055 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_055 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLP
::::::.:::::::::::::::::::::::::::: :::::::::::::::::::::::
NP_055 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT
::::::::::::::::::.::::..::::::::::::::::::::::::::::::::::.
NP_055 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
:::::: ::::::..:::::::::::::::::::::::::::::::::::::::.:::::
NP_055 AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGTPSTSS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 PAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPK
::::::::::: ::::::::::::::::::: ::::::::.:::::::::::..:::: :
NP_055 PAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 VKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSE
::::::::::::::::::.::::::::::::::::::::::: :::::::::::::: ::
NP_055 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 HFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
::::.:::: :::::::::: :::::::::::::::::::::::::::::::::::::::
NP_055 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_055 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQS
:::::::::::::::::.::::::::::::::::::::::::::::: ::::::::::::
NP_055 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 EQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSR
::::::::. ::.:::::: ::::::::::::::::::.::: :::::::::::::::::
NP_055 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
1570 1580 1590 1600 1610 1620
1630
pF1KA0 DSEAPTEEESEALP
NP_055 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDLYKPLSATRINNHAWKLHKKSSNEDKIL
1630 1640 1650 1660 1670 1680
>>XP_011523144 (OMIM: 616556) PREDICTED: leucine-rich re (1665 aa)
initn: 10263 init1: 10263 opt: 10263 Z-score: 4517.8 bits: 848.9 E(85289): 0
Smith-Waterman score: 10309; 95.7% identity (96.9% similar) in 1620 aa overlap (1-1620:1-1585)
10 20 30 40 50 60
pF1KA0 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
:.:::::::.:::: ::::::::::::::::::::::::::::::::::::::::::. :
XP_011 MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_011 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL
:::::::::::::::::::::::::::::::::::::::::::::: .::::::::::::
XP_011 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_011 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
::::::::::::::::::::::::::: ::::::::::::::: ::::::::::::::::
XP_011 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLP
::::::.:::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_011 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT
::::::::::::::::::.::::..::::::::::::::::::::::::::::::::::.
XP_011 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
:::::::::::::..:::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 PAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPK
::::::::::::::::::::::::::::::: ::::::::.:::::::::::..::::::
XP_011 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 VKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSE
::::::::::::::::::.::::::::::::::::::::::: :::::::::::::::::
XP_011 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 HFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
::::::::: :::::::::: ::::::::::::::::::::: :::::::::::::::::
XP_011 HFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
XP_011 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQS
:::::::::::::::::.::::::::::::::::::::::::::::: ::::::::::::
XP_011 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 EQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSR
:::::::: :::::::::::::::::
XP_011 EQKEKSLE-----------------------------------ICCHRRSLQEDEEGFSR
1570 1580
1630
pF1KA0 DSEAPTEEESEALP
XP_011 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKIL
1590 1600 1610 1620 1630 1640
>>XP_005257936 (OMIM: 616555) PREDICTED: leucine-rich re (1665 aa)
initn: 10224 init1: 10224 opt: 10224 Z-score: 4500.7 bits: 845.7 E(85289): 0
Smith-Waterman score: 10270; 95.6% identity (96.7% similar) in 1620 aa overlap (1-1620:1-1585)
10 20 30 40 50 60
pF1KA0 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
:.:::::::.:::: ::::::::::::::::::::::::::::::::::::::::::: :
XP_005 MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_005 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL
:::::::::::::::::::::::::::::::::::::::::::::: .::::::::::::
XP_005 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_005 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_005 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_005 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLP
::::::.:::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_005 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT
::::::::::::::::::.::::..::::::::::::::::::::::::::::::::::.
XP_005 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
:::::: ::::::..:::::::::::::::::::::::::::::::::::::::.:::::
XP_005 AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGTPSTSS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 PAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPK
::::::::::: ::::::::::::::::::: ::::::::.:::::::::::..:::: :
XP_005 PAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 VKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSE
::::::::::::::::::.::::::::::::::::::::::: :::::::::::::: ::
XP_005 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 HFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
::::.:::: :::::::::: :::::::::::::::::::::::::::::::::::::::
XP_005 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
XP_005 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQS
:::::::::::::::::.::::::::::::::::::::::::::::: ::::::::::::
XP_005 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 EQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSR
:::::::: :::::::::::::::::
XP_005 EQKEKSLE-----------------------------------ICCHRRSLQEDEEGFSR
1570 1580
1630
pF1KA0 DSEAPTEEESEALP
XP_005 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDLYKPLSATRINNHAWKLHKKSSNEDKIL
1590 1600 1610 1620 1630 1640
>>XP_016880088 (OMIM: 616557) PREDICTED: leucine-rich re (1544 aa)
initn: 10641 init1: 9985 opt: 9985 Z-score: 4396.5 bits: 826.3 E(85289): 0
Smith-Waterman score: 9985; 99.9% identity (100.0% similar) in 1510 aa overlap (95-1604:1-1510)
70 80 90 100 110 120
pF1KA0 SHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPE
::::::::::::::::::::::::::::::
XP_016 MPAPPQESTENLVPFLDTWDSAGELPLEPE
10 20 30
130 140 150 160 170 180
pF1KA0 QFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEY
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA0 SSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPA
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA0 QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADV
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA0 EVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPV
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA0 QPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE
280 290 300 310 320 330
430 440 450 460 470 480
pF1KA0 PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA0 PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA0 QPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA0 SVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 PLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLE
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 LTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLH
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCI
700 710 720 730 740 750
850 860 870 880 890 900
pF1KA0 DLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTEL
760 770 780 790 800 810
910 920 930 940 950 960
pF1KA0 HKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQ
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KA0 FLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHM
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KA0 ACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTE
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KA0 LIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKL
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KA0 PTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEK
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KA0 RLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKA
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KA0 LPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKS
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KA0 PKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIE
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420 1430 1440
pF1KA0 NNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETK
1300 1310 1320 1330 1340 1350
1450 1460 1470 1480 1490 1500
pF1KA0 WEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMD
1360 1370 1380 1390 1400 1410
1510 1520 1530 1540 1550 1560
pF1KA0 CSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKE
1420 1430 1440 1450 1460 1470
1570 1580 1590 1600 1610 1620
pF1KA0 KSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEA
:::::::::::::::::::::::::::::::::::::::.
XP_016 KSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEVRTIINSGFQNAVLSLCGFRA
1480 1490 1500 1510 1520 1530
1630
pF1KA0 PTEEESEALP
XP_016 HKLKTKATFPPAAT
1540
>>XP_016880961 (OMIM: 616555) PREDICTED: leucine-rich re (1606 aa)
initn: 9843 init1: 9843 opt: 9843 Z-score: 4334.0 bits: 814.8 E(85289): 0
Smith-Waterman score: 9843; 97.4% identity (98.8% similar) in 1526 aa overlap (95-1620:1-1526)
70 80 90 100 110 120
pF1KA0 SHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPE
:::::::::::::::::::::::: :::::
XP_016 MPAPPQESTENLVPFLDTWDSAGEQPLEPE
10 20 30
130 140 150 160 170 180
pF1KA0 QFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEY
:::::::::::::::::::::::::::::::::::::::::: .::::::::::::::::
XP_016 QFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEY
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA0 SSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPA
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA0 QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADV
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA0 EVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPV
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA0 QPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE
280 290 300 310 320 330
430 440 450 460 470 480
pF1KA0 PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA0 PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA0 QPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA0 SVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 PLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLE
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 LTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLH
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
XP_016 LTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLH
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCI
700 710 720 730 740 750
850 860 870 880 890 900
pF1KA0 DLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTEL
760 770 780 790 800 810
910 920 930 940 950 960
pF1KA0 HKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQ
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KA0 FLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_016 FLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLILPSHM
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KA0 ACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTE
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KA0 LIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKL
::.:::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_016 LIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLPFIKL
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KA0 PTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEK
::::::::::::::.::::..::::::::::::::::::::::::::::::::::.::::
XP_016 PTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENAAEEK
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KA0 RLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKA
:: ::::::..:::::::::::::::::::::::::::::::::::::::.:::::::::
XP_016 RLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGTPSTSSPAKA
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KA0 LPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKS
::::::: ::::::::::::::::::: ::::::::.:::::::::::..:::: :::::
XP_016 LPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTKVKKS
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KA0 PKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIE
::::::::::::::.::::::::::::::::::::::: :::::::::::::: ::::::
XP_016 PKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSEHFIE
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420 1430 1440
pF1KA0 NNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETK
.:::: :::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 KNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETK
1300 1310 1320 1330 1340 1350
1450 1460 1470 1480 1490 1500
pF1KA0 WEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMD
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_016 WEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRTLKMD
1360 1370 1380 1390 1400 1410
1510 1520 1530 1540 1550 1560
pF1KA0 CSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKE
:::::::::::::.::::::::::::::::::::::::::::: ::::::::::::::::
XP_016 CSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQSEQKE
1420 1430 1440 1450 1460 1470
1570 1580 1590 1600 1610 1620
pF1KA0 KSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEA
::::. ::.:::::: ::::::::::::::::::.::: :::::::::::::::::
XP_016 KSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSRGIFR
1480 1490 1500 1510 1520 1530
1630
pF1KA0 PTEEESEALP
XP_016 FLPWRGCSSRRESQDGLSSFGQPLWFKDLYKPLSATRINNHAWKLHKKSSNEDKILNRDP
1540 1550 1560 1570 1580 1590
>>XP_005257939 (OMIM: 616555) PREDICTED: leucine-rich re (1606 aa)
initn: 9843 init1: 9843 opt: 9843 Z-score: 4334.0 bits: 814.8 E(85289): 0
Smith-Waterman score: 9843; 97.4% identity (98.8% similar) in 1526 aa overlap (95-1620:1-1526)
70 80 90 100 110 120
pF1KA0 SHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPE
:::::::::::::::::::::::: :::::
XP_005 MPAPPQESTENLVPFLDTWDSAGEQPLEPE
10 20 30
130 140 150 160 170 180
pF1KA0 QFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEY
:::::::::::::::::::::::::::::::::::::::::: .::::::::::::::::
XP_005 QFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEY
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA0 SSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPA
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA0 QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADV
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA0 EVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPV
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA0 QPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE
280 290 300 310 320 330
430 440 450 460 470 480
pF1KA0 PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA0 PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA0 QPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA0 SVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 PLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLE
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 LTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLH
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
XP_005 LTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLH
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCI
700 710 720 730 740 750
850 860 870 880 890 900
pF1KA0 DLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTEL
760 770 780 790 800 810
910 920 930 940 950 960
pF1KA0 HKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQ
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KA0 FLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_005 FLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLILPSHM
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KA0 ACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTE
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KA0 LIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKL
::.:::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_005 LIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLPFIKL
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KA0 PTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEK
::::::::::::::.::::..::::::::::::::::::::::::::::::::::.::::
XP_005 PTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENAAEEK
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KA0 RLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKA
:: ::::::..:::::::::::::::::::::::::::::::::::::::.:::::::::
XP_005 RLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGTPSTSSPAKA
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KA0 LPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKS
::::::: ::::::::::::::::::: ::::::::.:::::::::::..:::: :::::
XP_005 LPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTKVKKS
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KA0 PKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIE
::::::::::::::.::::::::::::::::::::::: :::::::::::::: ::::::
XP_005 PKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSEHFIE
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420 1430 1440
pF1KA0 NNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETK
.:::: :::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_005 KNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETK
1300 1310 1320 1330 1340 1350
1450 1460 1470 1480 1490 1500
pF1KA0 WEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMD
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_005 WEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRTLKMD
1360 1370 1380 1390 1400 1410
1510 1520 1530 1540 1550 1560
pF1KA0 CSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKE
:::::::::::::.::::::::::::::::::::::::::::: ::::::::::::::::
XP_005 CSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQSEQKE
1420 1430 1440 1450 1460 1470
1570 1580 1590 1600 1610 1620
pF1KA0 KSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEA
::::. ::.:::::: ::::::::::::::::::.::: :::::::::::::::::
XP_005 KSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSRGIFR
1480 1490 1500 1510 1520 1530
1630
pF1KA0 PTEEESEALP
XP_005 FLPWRGCSSRRESQDGLSSFGQPLWFKDLYKPLSATRINNHAWKLHKKSSNEDKILNRDP
1540 1550 1560 1570 1580 1590
>>XP_016880089 (OMIM: 616557) PREDICTED: leucine-rich re (1018 aa)
initn: 6883 init1: 6883 opt: 6883 Z-score: 3039.3 bits: 574.6 E(85289): 1.5e-162
Smith-Waterman score: 6883; 100.0% identity (100.0% similar) in 1018 aa overlap (1-1018:1-1018)
10 20 30 40 50 60
pF1KA0 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKL
970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA0 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
1634 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:17:40 2016 done: Wed Nov 2 19:17:42 2016
Total Scan time: 17.610 Total Display time: 0.790
Function used was FASTA [36.3.4 Apr, 2011]