FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0575, 947 aa
1>>>pF1KA0575 947 - 947 aa - 947 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0935+/-0.000509; mu= -5.3275+/- 0.032
mean_var=280.7691+/-58.343, 0's: 0 Z-trim(117.9): 6 B-trim: 331 in 1/50
Lambda= 0.076542
statistics sampled from 30224 (30230) to 30224 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.354), width: 16
Scan time: 14.430
The best scores are: opt bits E(85289)
XP_005246253 (OMIM: 611736) PREDICTED: protein GRE (1038) 6425 723.8 1.1e-207
XP_011508724 (OMIM: 611736) PREDICTED: protein GRE (1073) 6425 723.8 1.1e-207
XP_011508720 (OMIM: 611736) PREDICTED: protein GRE (1948) 6425 723.9 1.9e-207
XP_011508721 (OMIM: 611736) PREDICTED: protein GRE (1948) 6425 723.9 1.9e-207
NP_055483 (OMIM: 611736) protein GREB1 isoform a [ (1949) 6425 723.9 1.9e-207
XP_005246249 (OMIM: 611736) PREDICTED: protein GRE (1949) 6425 723.9 1.9e-207
>>XP_005246253 (OMIM: 611736) PREDICTED: protein GREB1 i (1038 aa)
initn: 6425 init1: 6425 opt: 6425 Z-score: 3849.7 bits: 723.8 E(85289): 1.1e-207
Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:92-1038)
10 20 30
pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM
::::::::::::::::::::::::::::::
XP_005 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM
70 80 90 100 110 120
40 50 60 70 80 90
pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
130 140 150 160 170 180
100 110 120 130 140 150
pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
190 200 210 220 230 240
160 170 180 190 200 210
pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
250 260 270 280 290 300
220 230 240 250 260 270
pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
310 320 330 340 350 360
280 290 300 310 320 330
pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
370 380 390 400 410 420
340 350 360 370 380 390
pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
430 440 450 460 470 480
400 410 420 430 440 450
pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
490 500 510 520 530 540
460 470 480 490 500 510
pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
550 560 570 580 590 600
520 530 540 550 560 570
pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
610 620 630 640 650 660
580 590 600 610 620 630
pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
670 680 690 700 710 720
640 650 660 670 680 690
pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
730 740 750 760 770 780
700 710 720 730 740 750
pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
790 800 810 820 830 840
760 770 780 790 800 810
pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
850 860 870 880 890 900
820 830 840 850 860 870
pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
910 920 930 940 950 960
880 890 900 910 920 930
pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
970 980 990 1000 1010 1020
940
pF1KA0 ANAREDRPLFFLTGRHI
:::::::::::::::::
XP_005 ANAREDRPLFFLTGRHI
1030
>>XP_011508724 (OMIM: 611736) PREDICTED: protein GREB1 i (1073 aa)
initn: 6425 init1: 6425 opt: 6425 Z-score: 3849.5 bits: 723.8 E(85289): 1.1e-207
Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:127-1073)
10 20 30
pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM
::::::::::::::::::::::::::::::
XP_011 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM
100 110 120 130 140 150
40 50 60 70 80 90
pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
160 170 180 190 200 210
100 110 120 130 140 150
pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
220 230 240 250 260 270
160 170 180 190 200 210
pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
280 290 300 310 320 330
220 230 240 250 260 270
pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
340 350 360 370 380 390
280 290 300 310 320 330
pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
400 410 420 430 440 450
340 350 360 370 380 390
pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
460 470 480 490 500 510
400 410 420 430 440 450
pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
520 530 540 550 560 570
460 470 480 490 500 510
pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
580 590 600 610 620 630
520 530 540 550 560 570
pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
640 650 660 670 680 690
580 590 600 610 620 630
pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
700 710 720 730 740 750
640 650 660 670 680 690
pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
760 770 780 790 800 810
700 710 720 730 740 750
pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
820 830 840 850 860 870
760 770 780 790 800 810
pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
880 890 900 910 920 930
820 830 840 850 860 870
pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
940 950 960 970 980 990
880 890 900 910 920 930
pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
1000 1010 1020 1030 1040 1050
940
pF1KA0 ANAREDRPLFFLTGRHI
:::::::::::::::::
XP_011 ANAREDRPLFFLTGRHI
1060 1070
>>XP_011508720 (OMIM: 611736) PREDICTED: protein GREB1 i (1948 aa)
initn: 6425 init1: 6425 opt: 6425 Z-score: 3845.5 bits: 723.9 E(85289): 1.9e-207
Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:1002-1948)
10 20 30
pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM
::::::::::::::::::::::::::::::
XP_011 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM
980 990 1000 1010 1020 1030
40 50 60 70 80 90
pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
1040 1050 1060 1070 1080 1090
100 110 120 130 140 150
pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
1100 1110 1120 1130 1140 1150
160 170 180 190 200 210
pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
1160 1170 1180 1190 1200 1210
220 230 240 250 260 270
pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
1220 1230 1240 1250 1260 1270
280 290 300 310 320 330
pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
1280 1290 1300 1310 1320 1330
340 350 360 370 380 390
pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
1340 1350 1360 1370 1380 1390
400 410 420 430 440 450
pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
1400 1410 1420 1430 1440 1450
460 470 480 490 500 510
pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
1460 1470 1480 1490 1500 1510
520 530 540 550 560 570
pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
1520 1530 1540 1550 1560 1570
580 590 600 610 620 630
pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
1580 1590 1600 1610 1620 1630
640 650 660 670 680 690
pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
1640 1650 1660 1670 1680 1690
700 710 720 730 740 750
pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
1700 1710 1720 1730 1740 1750
760 770 780 790 800 810
pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
1760 1770 1780 1790 1800 1810
820 830 840 850 860 870
pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
1820 1830 1840 1850 1860 1870
880 890 900 910 920 930
pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
1880 1890 1900 1910 1920 1930
940
pF1KA0 ANAREDRPLFFLTGRHI
:::::::::::::::::
XP_011 ANAREDRPLFFLTGRHI
1940
>>XP_011508721 (OMIM: 611736) PREDICTED: protein GREB1 i (1948 aa)
initn: 6425 init1: 6425 opt: 6425 Z-score: 3845.5 bits: 723.9 E(85289): 1.9e-207
Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:1002-1948)
10 20 30
pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM
::::::::::::::::::::::::::::::
XP_011 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM
980 990 1000 1010 1020 1030
40 50 60 70 80 90
pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
1040 1050 1060 1070 1080 1090
100 110 120 130 140 150
pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
1100 1110 1120 1130 1140 1150
160 170 180 190 200 210
pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
1160 1170 1180 1190 1200 1210
220 230 240 250 260 270
pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
1220 1230 1240 1250 1260 1270
280 290 300 310 320 330
pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
1280 1290 1300 1310 1320 1330
340 350 360 370 380 390
pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
1340 1350 1360 1370 1380 1390
400 410 420 430 440 450
pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
1400 1410 1420 1430 1440 1450
460 470 480 490 500 510
pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
1460 1470 1480 1490 1500 1510
520 530 540 550 560 570
pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
1520 1530 1540 1550 1560 1570
580 590 600 610 620 630
pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
1580 1590 1600 1610 1620 1630
640 650 660 670 680 690
pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
1640 1650 1660 1670 1680 1690
700 710 720 730 740 750
pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
1700 1710 1720 1730 1740 1750
760 770 780 790 800 810
pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
1760 1770 1780 1790 1800 1810
820 830 840 850 860 870
pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
1820 1830 1840 1850 1860 1870
880 890 900 910 920 930
pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
1880 1890 1900 1910 1920 1930
940
pF1KA0 ANAREDRPLFFLTGRHI
:::::::::::::::::
XP_011 ANAREDRPLFFLTGRHI
1940
>>NP_055483 (OMIM: 611736) protein GREB1 isoform a [Homo (1949 aa)
initn: 6425 init1: 6425 opt: 6425 Z-score: 3845.5 bits: 723.9 E(85289): 1.9e-207
Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:1003-1949)
10 20 30
pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM
::::::::::::::::::::::::::::::
NP_055 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM
980 990 1000 1010 1020 1030
40 50 60 70 80 90
pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
1040 1050 1060 1070 1080 1090
100 110 120 130 140 150
pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
1100 1110 1120 1130 1140 1150
160 170 180 190 200 210
pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
1160 1170 1180 1190 1200 1210
220 230 240 250 260 270
pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
1220 1230 1240 1250 1260 1270
280 290 300 310 320 330
pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
1280 1290 1300 1310 1320 1330
340 350 360 370 380 390
pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
1340 1350 1360 1370 1380 1390
400 410 420 430 440 450
pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
1400 1410 1420 1430 1440 1450
460 470 480 490 500 510
pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
1460 1470 1480 1490 1500 1510
520 530 540 550 560 570
pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
1520 1530 1540 1550 1560 1570
580 590 600 610 620 630
pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
1580 1590 1600 1610 1620 1630
640 650 660 670 680 690
pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
1640 1650 1660 1670 1680 1690
700 710 720 730 740 750
pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
1700 1710 1720 1730 1740 1750
760 770 780 790 800 810
pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
1760 1770 1780 1790 1800 1810
820 830 840 850 860 870
pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
1820 1830 1840 1850 1860 1870
880 890 900 910 920 930
pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
1880 1890 1900 1910 1920 1930
940
pF1KA0 ANAREDRPLFFLTGRHI
:::::::::::::::::
NP_055 ANAREDRPLFFLTGRHI
1940
>>XP_005246249 (OMIM: 611736) PREDICTED: protein GREB1 i (1949 aa)
initn: 6425 init1: 6425 opt: 6425 Z-score: 3845.5 bits: 723.9 E(85289): 1.9e-207
Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:1003-1949)
10 20 30
pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM
::::::::::::::::::::::::::::::
XP_005 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM
980 990 1000 1010 1020 1030
40 50 60 70 80 90
pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE
1040 1050 1060 1070 1080 1090
100 110 120 130 140 150
pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL
1100 1110 1120 1130 1140 1150
160 170 180 190 200 210
pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ
1160 1170 1180 1190 1200 1210
220 230 240 250 260 270
pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST
1220 1230 1240 1250 1260 1270
280 290 300 310 320 330
pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR
1280 1290 1300 1310 1320 1330
340 350 360 370 380 390
pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY
1340 1350 1360 1370 1380 1390
400 410 420 430 440 450
pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT
1400 1410 1420 1430 1440 1450
460 470 480 490 500 510
pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS
1460 1470 1480 1490 1500 1510
520 530 540 550 560 570
pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH
1520 1530 1540 1550 1560 1570
580 590 600 610 620 630
pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI
1580 1590 1600 1610 1620 1630
640 650 660 670 680 690
pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA
1640 1650 1660 1670 1680 1690
700 710 720 730 740 750
pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA
1700 1710 1720 1730 1740 1750
760 770 780 790 800 810
pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL
1760 1770 1780 1790 1800 1810
820 830 840 850 860 870
pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS
1820 1830 1840 1850 1860 1870
880 890 900 910 920 930
pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT
1880 1890 1900 1910 1920 1930
940
pF1KA0 ANAREDRPLFFLTGRHI
:::::::::::::::::
XP_005 ANAREDRPLFFLTGRHI
1940
947 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:44:38 2016 done: Thu Nov 3 09:44:40 2016
Total Scan time: 14.430 Total Display time: 0.240
Function used was FASTA [36.3.4 Apr, 2011]