FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0575, 947 aa 1>>>pF1KA0575 947 - 947 aa - 947 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.0935+/-0.000509; mu= -5.3275+/- 0.032 mean_var=280.7691+/-58.343, 0's: 0 Z-trim(117.9): 6 B-trim: 331 in 1/50 Lambda= 0.076542 statistics sampled from 30224 (30230) to 30224 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.354), width: 16 Scan time: 14.430 The best scores are: opt bits E(85289) XP_005246253 (OMIM: 611736) PREDICTED: protein GRE (1038) 6425 723.8 1.1e-207 XP_011508724 (OMIM: 611736) PREDICTED: protein GRE (1073) 6425 723.8 1.1e-207 XP_011508720 (OMIM: 611736) PREDICTED: protein GRE (1948) 6425 723.9 1.9e-207 XP_011508721 (OMIM: 611736) PREDICTED: protein GRE (1948) 6425 723.9 1.9e-207 NP_055483 (OMIM: 611736) protein GREB1 isoform a [ (1949) 6425 723.9 1.9e-207 XP_005246249 (OMIM: 611736) PREDICTED: protein GRE (1949) 6425 723.9 1.9e-207 >>XP_005246253 (OMIM: 611736) PREDICTED: protein GREB1 i (1038 aa) initn: 6425 init1: 6425 opt: 6425 Z-score: 3849.7 bits: 723.8 E(85289): 1.1e-207 Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:92-1038) 10 20 30 pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM :::::::::::::::::::::::::::::: XP_005 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM 70 80 90 100 110 120 40 50 60 70 80 90 pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE 130 140 150 160 170 180 100 110 120 130 140 150 pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL 190 200 210 220 230 240 160 170 180 190 200 210 pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ 250 260 270 280 290 300 220 230 240 250 260 270 pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST 310 320 330 340 350 360 280 290 300 310 320 330 pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR 370 380 390 400 410 420 340 350 360 370 380 390 pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY 430 440 450 460 470 480 400 410 420 430 440 450 pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT 490 500 510 520 530 540 460 470 480 490 500 510 pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS 550 560 570 580 590 600 520 530 540 550 560 570 pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH 610 620 630 640 650 660 580 590 600 610 620 630 pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI 670 680 690 700 710 720 640 650 660 670 680 690 pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA 730 740 750 760 770 780 700 710 720 730 740 750 pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA 790 800 810 820 830 840 760 770 780 790 800 810 pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL 850 860 870 880 890 900 820 830 840 850 860 870 pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS 910 920 930 940 950 960 880 890 900 910 920 930 pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT 970 980 990 1000 1010 1020 940 pF1KA0 ANAREDRPLFFLTGRHI ::::::::::::::::: XP_005 ANAREDRPLFFLTGRHI 1030 >>XP_011508724 (OMIM: 611736) PREDICTED: protein GREB1 i (1073 aa) initn: 6425 init1: 6425 opt: 6425 Z-score: 3849.5 bits: 723.8 E(85289): 1.1e-207 Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:127-1073) 10 20 30 pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM :::::::::::::::::::::::::::::: XP_011 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM 100 110 120 130 140 150 40 50 60 70 80 90 pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE 160 170 180 190 200 210 100 110 120 130 140 150 pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL 220 230 240 250 260 270 160 170 180 190 200 210 pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ 280 290 300 310 320 330 220 230 240 250 260 270 pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST 340 350 360 370 380 390 280 290 300 310 320 330 pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR 400 410 420 430 440 450 340 350 360 370 380 390 pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY 460 470 480 490 500 510 400 410 420 430 440 450 pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT 520 530 540 550 560 570 460 470 480 490 500 510 pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS 580 590 600 610 620 630 520 530 540 550 560 570 pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH 640 650 660 670 680 690 580 590 600 610 620 630 pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI 700 710 720 730 740 750 640 650 660 670 680 690 pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA 760 770 780 790 800 810 700 710 720 730 740 750 pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA 820 830 840 850 860 870 760 770 780 790 800 810 pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL 880 890 900 910 920 930 820 830 840 850 860 870 pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS 940 950 960 970 980 990 880 890 900 910 920 930 pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT 1000 1010 1020 1030 1040 1050 940 pF1KA0 ANAREDRPLFFLTGRHI ::::::::::::::::: XP_011 ANAREDRPLFFLTGRHI 1060 1070 >>XP_011508720 (OMIM: 611736) PREDICTED: protein GREB1 i (1948 aa) initn: 6425 init1: 6425 opt: 6425 Z-score: 3845.5 bits: 723.9 E(85289): 1.9e-207 Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:1002-1948) 10 20 30 pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM :::::::::::::::::::::::::::::: XP_011 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM 980 990 1000 1010 1020 1030 40 50 60 70 80 90 pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE 1040 1050 1060 1070 1080 1090 100 110 120 130 140 150 pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL 1100 1110 1120 1130 1140 1150 160 170 180 190 200 210 pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ 1160 1170 1180 1190 1200 1210 220 230 240 250 260 270 pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST 1220 1230 1240 1250 1260 1270 280 290 300 310 320 330 pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR 1280 1290 1300 1310 1320 1330 340 350 360 370 380 390 pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY 1340 1350 1360 1370 1380 1390 400 410 420 430 440 450 pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT 1400 1410 1420 1430 1440 1450 460 470 480 490 500 510 pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS 1460 1470 1480 1490 1500 1510 520 530 540 550 560 570 pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH 1520 1530 1540 1550 1560 1570 580 590 600 610 620 630 pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI 1580 1590 1600 1610 1620 1630 640 650 660 670 680 690 pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA 1640 1650 1660 1670 1680 1690 700 710 720 730 740 750 pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA 1700 1710 1720 1730 1740 1750 760 770 780 790 800 810 pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL 1760 1770 1780 1790 1800 1810 820 830 840 850 860 870 pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS 1820 1830 1840 1850 1860 1870 880 890 900 910 920 930 pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT 1880 1890 1900 1910 1920 1930 940 pF1KA0 ANAREDRPLFFLTGRHI ::::::::::::::::: XP_011 ANAREDRPLFFLTGRHI 1940 >>XP_011508721 (OMIM: 611736) PREDICTED: protein GREB1 i (1948 aa) initn: 6425 init1: 6425 opt: 6425 Z-score: 3845.5 bits: 723.9 E(85289): 1.9e-207 Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:1002-1948) 10 20 30 pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM :::::::::::::::::::::::::::::: XP_011 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM 980 990 1000 1010 1020 1030 40 50 60 70 80 90 pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE 1040 1050 1060 1070 1080 1090 100 110 120 130 140 150 pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL 1100 1110 1120 1130 1140 1150 160 170 180 190 200 210 pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ 1160 1170 1180 1190 1200 1210 220 230 240 250 260 270 pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST 1220 1230 1240 1250 1260 1270 280 290 300 310 320 330 pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR 1280 1290 1300 1310 1320 1330 340 350 360 370 380 390 pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY 1340 1350 1360 1370 1380 1390 400 410 420 430 440 450 pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT 1400 1410 1420 1430 1440 1450 460 470 480 490 500 510 pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS 1460 1470 1480 1490 1500 1510 520 530 540 550 560 570 pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH 1520 1530 1540 1550 1560 1570 580 590 600 610 620 630 pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI 1580 1590 1600 1610 1620 1630 640 650 660 670 680 690 pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA 1640 1650 1660 1670 1680 1690 700 710 720 730 740 750 pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA 1700 1710 1720 1730 1740 1750 760 770 780 790 800 810 pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL 1760 1770 1780 1790 1800 1810 820 830 840 850 860 870 pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS 1820 1830 1840 1850 1860 1870 880 890 900 910 920 930 pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT 1880 1890 1900 1910 1920 1930 940 pF1KA0 ANAREDRPLFFLTGRHI ::::::::::::::::: XP_011 ANAREDRPLFFLTGRHI 1940 >>NP_055483 (OMIM: 611736) protein GREB1 isoform a [Homo (1949 aa) initn: 6425 init1: 6425 opt: 6425 Z-score: 3845.5 bits: 723.9 E(85289): 1.9e-207 Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:1003-1949) 10 20 30 pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM :::::::::::::::::::::::::::::: NP_055 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM 980 990 1000 1010 1020 1030 40 50 60 70 80 90 pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE 1040 1050 1060 1070 1080 1090 100 110 120 130 140 150 pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL 1100 1110 1120 1130 1140 1150 160 170 180 190 200 210 pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ 1160 1170 1180 1190 1200 1210 220 230 240 250 260 270 pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST 1220 1230 1240 1250 1260 1270 280 290 300 310 320 330 pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR 1280 1290 1300 1310 1320 1330 340 350 360 370 380 390 pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY 1340 1350 1360 1370 1380 1390 400 410 420 430 440 450 pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT 1400 1410 1420 1430 1440 1450 460 470 480 490 500 510 pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS 1460 1470 1480 1490 1500 1510 520 530 540 550 560 570 pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH 1520 1530 1540 1550 1560 1570 580 590 600 610 620 630 pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI 1580 1590 1600 1610 1620 1630 640 650 660 670 680 690 pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA 1640 1650 1660 1670 1680 1690 700 710 720 730 740 750 pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA 1700 1710 1720 1730 1740 1750 760 770 780 790 800 810 pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL 1760 1770 1780 1790 1800 1810 820 830 840 850 860 870 pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS 1820 1830 1840 1850 1860 1870 880 890 900 910 920 930 pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT 1880 1890 1900 1910 1920 1930 940 pF1KA0 ANAREDRPLFFLTGRHI ::::::::::::::::: NP_055 ANAREDRPLFFLTGRHI 1940 >>XP_005246249 (OMIM: 611736) PREDICTED: protein GREB1 i (1949 aa) initn: 6425 init1: 6425 opt: 6425 Z-score: 3845.5 bits: 723.9 E(85289): 1.9e-207 Smith-Waterman score: 6425; 100.0% identity (100.0% similar) in 947 aa overlap (1-947:1003-1949) 10 20 30 pF1KA0 MWQKIEDVEWRPQTYLELEGLPCILIFSGM :::::::::::::::::::::::::::::: XP_005 RLALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSGM 980 990 1000 1010 1020 1030 40 50 60 70 80 90 pF1KA0 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALESDAE 1040 1050 1060 1070 1080 1090 100 110 120 130 140 150 pF1KA0 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTAL 1100 1110 1120 1130 1140 1150 160 170 180 190 200 210 pF1KA0 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRSVQ 1160 1170 1180 1190 1200 1210 220 230 240 250 260 270 pF1KA0 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKLVYDMVVST 1220 1230 1240 1250 1260 1270 280 290 300 310 320 330 pF1KA0 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPSHMDYGNRAEGR 1280 1290 1300 1310 1320 1330 340 350 360 370 380 390 pF1KA0 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEEININLREESDWHY 1340 1350 1360 1370 1380 1390 400 410 420 430 440 450 pF1KA0 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDRGMSRKPEDLYVRRQT 1400 1410 1420 1430 1440 1450 460 470 480 490 500 510 pF1KA0 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFSYSMLGEEIQLHFIIPKS 1460 1470 1480 1490 1500 1510 520 530 540 550 560 570 pF1KA0 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGRHEHGLFNLYHAMDGASHLH 1520 1530 1540 1550 1560 1570 580 590 600 610 620 630 pF1KA0 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELSYHNLELERNRQEELGI 1580 1590 1600 1610 1620 1630 640 650 660 670 680 690 pF1KA0 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWSERNVSLKHIMQHIEAAPDIMHYA 1640 1650 1660 1670 1680 1690 700 710 720 730 740 750 pF1KA0 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDLTQNVQYNQNRFLCDDVDFNLRVHSA 1700 1710 1720 1730 1740 1750 760 770 780 790 800 810 pF1KA0 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSDNSAAVVPAQYICAPDSKHTFLAAPAQL 1760 1770 1780 1790 1800 1810 820 830 840 850 860 870 pF1KA0 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLEKFLQHHSHLFFPLSLKNHDHPVLSVDCYLNLGSQISVCYVSSRPHSLNISCSDLLFS 1820 1830 1840 1850 1860 1870 880 890 900 910 920 930 pF1KA0 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTVVRLELEDEWQFRLRDEFQT 1880 1890 1900 1910 1920 1930 940 pF1KA0 ANAREDRPLFFLTGRHI ::::::::::::::::: XP_005 ANAREDRPLFFLTGRHI 1940 947 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:44:38 2016 done: Thu Nov 3 09:44:40 2016 Total Scan time: 14.430 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]