FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0579, 949 aa 1>>>pF1KA0579 949 - 949 aa - 949 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.9378+/-0.000972; mu= 1.9544+/- 0.059 mean_var=288.0569+/-57.386, 0's: 0 Z-trim(115.5): 26 B-trim: 5 in 1/52 Lambda= 0.075568 statistics sampled from 16019 (16038) to 16019 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.493), width: 16 Scan time: 4.290 The best scores are: opt bits E(32554) CCDS10961.1 ZCCHC14 gene_id:23174|Hs108|chr16 ( 949) 6382 709.8 6.4e-204 CCDS45880.1 ZCCHC2 gene_id:54877|Hs108|chr18 (1178) 545 73.5 2.7e-12 >>CCDS10961.1 ZCCHC14 gene_id:23174|Hs108|chr16 (949 aa) initn: 6382 init1: 6382 opt: 6382 Z-score: 3774.5 bits: 709.8 E(32554): 6.4e-204 Smith-Waterman score: 6382; 100.0% identity (100.0% similar) in 949 aa overlap (1-949:1-949) 10 20 30 40 50 60 pF1KA0 MASNHPAFSFHQKQVLRQELTQIQSSLNGGGGHGGKGAPGPGGALPTCPACHKITPRTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MASNHPAFSFHQKQVLRQELTQIQSSLNGGGGHGGKGAPGPGGALPTCPACHKITPRTEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 PVSSVSNSLENALHTSAHSTEESLPKRPLGKHSKVSVEKIDLKGLSHTKNDRNVECSFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PVSSVSNSLENALHTSAHSTEESLPKRPLGKHSKVSVEKIDLKGLSHTKNDRNVECSFEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LWSDSSITSVTKSSSEVTEFISKLCQLYPEENLEKLIPCLAGPDAFYVERNHVDLDSGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LWSDSSITSVTKSSSEVTEFISKLCQLYPEENLEKLIPCLAGPDAFYVERNHVDLDSGLR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YLASLPSHVLKNDHVRRFLSTSSPPQQLQSPSPGNPSLSKVGTVMGVSGRPVCGVAGIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 YLASLPSHVLKNDHVRRFLSTSSPPQQLQSPSPGNPSLSKVGTVMGVSGRPVCGVAGIPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SQSGAQHHGQHPAGSAAPLPHCSHAGSAGSALAYRTQMDTSPAILMPSSLQTPQTQEQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SQSGAQHHGQHPAGSAAPLPHCSHAGSAGSALAYRTQMDTSPAILMPSSLQTPQTQEQNG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ILDWLRKLRLHKYYPVFKQLSMEKFLSLTEEDLNKFESLTMGAKKKLKTQLELEKEKSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ILDWLRKLRLHKYYPVFKQLSMEKFLSLTEEDLNKFESLTMGAKKKLKTQLELEKEKSER 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 RCLNPSAPPLVTSSGVARVPPTSHVGPVQSGRGSHAAELRVEVEQPHHQLPREGSSSEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 RCLNPSAPPLVTSSGVARVPPTSHVGPVQSGRGSHAAELRVEVEQPHHQLPREGSSSEYS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 SSSSSPMGVQAREESSDSAEENDRRVEIHLESSDKEKPVMLLNHFTSSSARPTAQVLPVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SSSSSPMGVQAREESSDSAEENDRRVEIHLESSDKEKPVMLLNHFTSSSARPTAQVLPVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 NEASSNPSGHHPLPPQMLSAASHITPIRMLNSVHKPERGSADMKLLSSSVHSLLSLEERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NEASSNPSGHHPLPPQMLSAASHITPIRMLNSVHKPERGSADMKLLSSSVHSLLSLEERN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 KGSGPRSSMKVDKSFGSAMMDVLPASAPHQPVQVLSGLSESSSMSPTVSFGPRTKVVHAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KGSGPRSSMKVDKSFGSAMMDVLPASAPHQPVQVLSGLSESSSMSPTVSFGPRTKVVHAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TLDRVLKTAQQPALVVETSTAATGTPSTVLHAARPPIKLLLSSSVPADSAISGQTSCPNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 TLDRVLKTAQQPALVVETSTAATGTPSTVLHAARPPIKLLLSSSVPADSAISGQTSCPNN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 VQISVPPAIINPRTALYTANTKVAFSAMSSMPVGPLQGGFCANSNTASPSSHPSTSFANM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VQISVPPAIINPRTALYTANTKVAFSAMSSMPVGPLQGGFCANSNTASPSSHPSTSFANM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ATLPSCPAPSSSPALSSVPESSFYSSSGGGGSTGNIPASNPNHHHHHHHQQPPAPPQPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ATLPSCPAPSSSPALSSVPESSFYSSSGGGGSTGNIPASNPNHHHHHHHQQPPAPPQPAP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 PPPGCIVCTSCGCSGSCGSSGLTVSYANYFQHPFSGPSVFTFPFLPFSPMCSSGYVSAQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PPPGCIVCTSCGCSGSCGSSGLTVSYANYFQHPFSGPSVFTFPFLPFSPMCSSGYVSAQQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 YGGGSTFPVVHAPYSSSGTPDPVLSGQSTFAVPPMQNFMAGTAGVYQTQGLVGSSNGSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 YGGGSTFPVVHAPYSSSGTPDPVLSGQSTFAVPPMQNFMAGTAGVYQTQGLVGSSNGSSH 850 860 870 880 890 900 910 920 930 940 pF1KA0 KKSGNLSCYNCGATGHRAQDCKQPSMDFNRPGTFRLKYAPPAESLDSTD ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KKSGNLSCYNCGATGHRAQDCKQPSMDFNRPGTFRLKYAPPAESLDSTD 910 920 930 940 >>CCDS45880.1 ZCCHC2 gene_id:54877|Hs108|chr18 (1178 aa) initn: 731 init1: 262 opt: 545 Z-score: 334.1 bits: 73.5 E(32554): 2.7e-12 Smith-Waterman score: 892; 27.1% identity (54.2% similar) in 1004 aa overlap (1-949:265-1178) 10 20 30 pF1KA0 MASNHPAFSFHQKQVLRQELTQIQSSLNGG ::: ::::::::. .::..: .....: :: CCDS45 GSGPEGGIVEPRVGGGLGSRAQEELLLLFTMASLHPAFSFHQRVTLREHLERLRAALRGG 240 250 260 270 280 290 40 50 60 70 80 pF1KA0 GGHGGKGAPGPGGALPTCPACHKITPRTE---APVSSVSNSLENALHTSAHSTEESLPKR : : :. ::.. : . ..:. :..: .: ...: CCDS45 ----------PEDAEVEVEPCKFAGPRAQNNSAHGDYMQNN-ESSLIEQAPIPQDGLTVA 300 310 320 330 340 90 100 110 120 130 140 pF1KA0 PL-GKHSKVSVEKIDLKGLSHTKNDRNVECSFEVLWSDSSITSVTKSSSEVTEFISKLCQ : ... : .::: :::... . :. : .:.: ::: :.:.:::. .:. ::. :: . CCDS45 PHRAQREAVHIEKIMLKGVQRKRADKYWEYTFKVNWSDLSVTTVTKTHQELQEFLLKLPK 350 360 370 380 390 400 150 160 170 180 190 200 pF1KA0 LYPEENLEKLI-PCLAGPDAFYVERNHVDLDSGLRYLASLPSHV-LKNDHVRRFLSTSSP :...: : : . :: : ::. :: : : :.. :....:. :... : CCDS45 ELSSETFDKTILRALNQGSLKREERRHPDLEPILRQLFSSSSQAFLQSQKVHSFFQSISS 410 420 430 440 450 460 210 220 230 240 250 260 pF1KA0 PQQLQSPSPGNPSLSKVGTVMGVSGRPVCGVAGIPSSQSGAQHHG--QHPAGSAAPLPHC ..:.: . . :: :.. .. . ::....:.. :: . : CCDS45 -DSLHSINNLQSSL-KTSKILEHLKED--------SSEASSQEEDVLQHA------IIHK 470 480 490 500 270 280 290 300 310 320 pF1KA0 SHAGSAGSALAYRTQMDTSPAILMPSSLQTPQTQEQNGILDWLRKLRLHKYYPVFKQLSM .:.:. : .. . :: ..: : : .:::::.:: .. .: CCDS45 KHTGK--SPIVNNIGTSCSPL----DGL-TMQYSEQNGIVDWRKQSCTTIQHP------- 510 520 530 540 550 330 340 350 360 370 380 pF1KA0 EKFLSLTEEDLNKFESLTMGAKKKLKTQLELEKEKSERRCLNPSAPPLVTSSGVARVPPT :. .. ... . .::. ::: : : : :: :. :: . :. : CCDS45 EHCVTSADQHSAEKRSLSSINKKKGKPQTEKEKIKKTDNRLNSRINGIRLST-----PQH 560 570 580 590 600 390 400 410 420 430 440 pF1KA0 SHVGPVQSGRGSHAAELRVEVEQPHHQLPREGSSSEYSSSSSSPMGVQAREESSDSAEEN .: : :. .. ... . : . .::: :: ::: . .:: .: ::. CCDS45 AHGGTVK--------DVNLDIGSGHDTCGE--TSSESYSSPSSPR--HDGRESFESEEEK 610 620 630 640 650 450 460 470 480 490 pF1KA0 DRRVEIHLESSDKEKPVMLLNHFT---SSSARPTAQVLPVQNEASS-------NPSGHHP :: .. . :.: . . . . .. . . ...: .:. . :: .. .:. .: CCDS45 DRDTDSNSEDSGNPSTTRFTGYGSVNQTVTVKPPVQIASLGNENGNLLEDPLNSPKYQHI 660 670 680 690 700 710 500 510 520 530 540 pF1KA0 --LPPQMLSAASHITPIRMLNSVHKPERGSADMKLLSSSVHSLLSLEERNKGS-----GP .: . ... . :: :.. :. : : .. ...: ... :: CCDS45 SFMPTLHCVMHNGAQKSEVVVPAPKPADGKTIGMLVPSPV-AISAIRESANSTPVGILGP 720 730 740 750 760 770 550 560 570 580 pF1KA0 RSSMKVDKSFGSAMMDVLP--------ASAP--HQPVQVLS-----GLSESSSMS-PTVS . ... . . :: .:.: : :: :. : ::: ... : CCDS45 TACTGESEKHLELLASPLPIPSTFLPHSSTPALHLTVQRLKLPPPQGSSESCTVNIPQQP 780 790 800 810 820 830 590 600 610 620 630 640 pF1KA0 FGPRTKVVHASTLDRVLKTAQQPALVVETSTAATGTPSTVLHAARPPIKLLLSSSVPADS : . . ... . . .. :. : :. : . : :. :.. :: CCDS45 PGSLSIASPNTAFIPIHNPGSFPGSPVATTDPITKSASQVVG---------LNQMVPQIE 840 850 860 870 880 650 660 670 680 690 700 pF1KA0 AISGQTSCPNNVQISVPPAIINPRTALYTANTKVAFSAMSSMPVGPLQGGFCANSN---- . .: . :.::.. .: : .: .:. ... .: .:: .: ..: CCDS45 GNTGTVPQPTNVKVVLPAA------GLSAAQPPASYP----LPGSPLAAGVLPSQNSSVL 890 900 910 920 930 710 720 730 740 750 760 pF1KA0 -TASPSSHPSTSFANMATLPSCPA-PSSSPALSSVPESSFYSSSGGGGSTGNIPA-SNPN ::. : .:... ..: :: :. .:. . : .. :.. . ::. : : .: : CCDS45 STAATSPQPASAGISQAQATVPPAVPTHTPGPAPSPSPALTHSTAQSDSTSYISAVGNTN 940 950 960 970 980 990 770 780 790 800 810 820 pF1KA0 HHHHHHHQQPPAPPQPAPPPPGCIVCTSCGCSGSCGSSGLTVSYANYFQHPFSGPSVFTF . .::: : : ::: :::..: . :. .:. :: .. CCDS45 AN------GTVVPPQQMGSGP----CGSCGRRCSCGTNGNLQLNSYYYPNPMPGP-MYRV 1000 1010 1020 1030 1040 830 840 850 860 870 pF1KA0 P-FLPFSPMCSSGYVSAQQYGGGSTFPVV--HAPYSSSGTPDPVLSGQSTFAVPPMQNFM : :. . .:...:.. . ..:. .: ..::... . :::...:..... : .: CCDS45 PSFFTLPSICNGSYLNQAHQSNGNQLPFFLPQTPYANGLVHDPVMGSQANYGMQQMAGF- 1050 1060 1070 1080 1090 1100 880 890 900 910 920 930 pF1KA0 AGTAGVYQTQGLVGSSNGSSHKKSGNLSCYNCGATGHRAQDCKQPSMDFNRPGTFRLKYA . :: . ..:....::. ::.::.::::::..:: :::::: ::. :. ::.::.:: CCDS45 GRFYPVYPAPNVVANTSGSGPKKNGNVSCYNCGVSGHYAQDCKQSSMEANQQGTYRLRYA 1110 1120 1130 1140 1150 1160 940 pF1KA0 PP----AESLDSTD :: ..:::.: CCDS45 PPLPPSNDTLDSAD 1170 949 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:20:30 2016 done: Wed Nov 2 19:20:31 2016 Total Scan time: 4.290 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]