Result of FASTA (omim) for
pF1KA0583
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0583, 1919 aa
1>>>pF1KA0583 1919 - 1919 aa - 1919 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.8042+/-0.000565; mu= -26.2587+/- 0.035
mean_var=559.8671+/-115.909, 0's: 0 Z-trim(120.2): 215 B-trim: 0 in 0/56
Lambda= 0.054204
statistics sampled from 34923 (35138) to 34923 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.412), width: 16
Scan time: 22.120
The best scores are: opt bits E(85289)
NP_004738 (OMIM: 604090) disks large homolog 5 [Ho (1919) 12665 1007.0 0
XP_005270333 (OMIM: 604090) PREDICTED: disks large (1915) 12612 1002.9 0
XP_011538643 (OMIM: 604090) PREDICTED: disks large (1860) 12025 957.0 0
XP_011538644 (OMIM: 604090) PREDICTED: disks large (1829) 12018 956.4 0
XP_016872402 (OMIM: 604090) PREDICTED: disks large (1825) 12016 956.3 0
XP_016872403 (OMIM: 604090) PREDICTED: disks large (1809) 11965 952.3 0
XP_011538646 (OMIM: 604090) PREDICTED: disks large (1807) 11884 946.0 0
XP_011538647 (OMIM: 604090) PREDICTED: disks large (1764) 11690 930.8 0
XP_011538648 (OMIM: 604090) PREDICTED: disks large (1680) 10924 870.9 0
XP_016872404 (OMIM: 604090) PREDICTED: disks large (1613) 10688 852.4 0
XP_011538649 (OMIM: 604090) PREDICTED: disks large (1613) 10688 852.4 0
XP_006718120 (OMIM: 604090) PREDICTED: disks large (1342) 8832 707.2 2.8e-202
XP_006718119 (OMIM: 604090) PREDICTED: disks large (1579) 5240 426.4 1.2e-117
XP_016861309 (OMIM: 601014) PREDICTED: disks large ( 853) 412 48.7 0.00031
XP_011510808 (OMIM: 601014) PREDICTED: disks large ( 853) 412 48.7 0.00031
XP_016861311 (OMIM: 601014) PREDICTED: disks large ( 821) 411 48.6 0.00032
NP_001191317 (OMIM: 601014) disks large homolog 1 ( 788) 405 48.1 0.00042
NP_001091894 (OMIM: 601014) disks large homolog 1 ( 904) 407 48.3 0.00042
NP_001277912 (OMIM: 601014) disks large homolog 1 ( 904) 407 48.3 0.00042
XP_016861294 (OMIM: 601014) PREDICTED: disks large ( 904) 407 48.3 0.00042
XP_011510804 (OMIM: 601014) PREDICTED: disks large ( 904) 407 48.3 0.00042
XP_016861308 (OMIM: 601014) PREDICTED: disks large ( 871) 405 48.1 0.00046
XP_016861305 (OMIM: 601014) PREDICTED: disks large ( 871) 405 48.1 0.00046
XP_016861306 (OMIM: 601014) PREDICTED: disks large ( 871) 405 48.1 0.00046
XP_016861307 (OMIM: 601014) PREDICTED: disks large ( 871) 405 48.1 0.00046
XP_011510807 (OMIM: 601014) PREDICTED: disks large ( 871) 405 48.1 0.00046
NP_001191316 (OMIM: 601014) disks large homolog 1 ( 800) 385 46.6 0.0013
XP_016861313 (OMIM: 601014) PREDICTED: disks large ( 519) 346 43.4 0.0072
>>NP_004738 (OMIM: 604090) disks large homolog 5 [Homo s (1919 aa)
initn: 12665 init1: 12665 opt: 12665 Z-score: 5370.1 bits: 1007.0 E(85289): 0
Smith-Waterman score: 12665; 99.9% identity (100.0% similar) in 1919 aa overlap (1-1919:1-1919)
10 20 30 40 50 60
pF1KA0 MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LAKERDHFQDLRAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LAKERDHFQDLRAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LSSVGTTGKAPSPPPLLTDRQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
NP_004 LSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KDDVDMLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KDDVDMLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 KLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 YREERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YREERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 AHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 HINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 LRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 STQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 STQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDAS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SIKFQHRLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SIKFQHRLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 GDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 ASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 SHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSAR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 SASTLPRIAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SASTLPRIAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVG
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 SIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 SSHLDPAGTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SSHLDPAGTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 RVVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RVVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTV
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 EEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDIL
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 YVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTL
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 SAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALR
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 PVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDV
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 TTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDK
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910
pF1KA0 VTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
1870 1880 1890 1900 1910
>>XP_005270333 (OMIM: 604090) PREDICTED: disks large hom (1915 aa)
initn: 11507 init1: 11507 opt: 12612 Z-score: 5347.7 bits: 1002.9 E(85289): 0
Smith-Waterman score: 12612; 99.7% identity (99.8% similar) in 1919 aa overlap (1-1919:1-1915)
10 20 30 40 50 60
pF1KA0 MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LAKERDHFQDLRAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAKERDHFQDLRAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LSSVGTTGKAPSPPPLLTDRQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP
:::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_005 LSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKR-
130 140 150 160 170
190 200 210 220 230 240
pF1KA0 YHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ---LNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 KDDVDMLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDDVDMLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILN
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 KLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 YREERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YREERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQI
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 KDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLM
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 AHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVD
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA0 KGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA0 HINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA0 LRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNN
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA0 STQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDAS
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA0 GDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEK
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 LSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSD
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA0 SIKFQHRLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIKFQHRLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPE
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KA0 GDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVP
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KA0 ASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVR
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KA0 SHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSAR
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KA0 LGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQT
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KA0 SASTLPRIAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SASTLPRIAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVG
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KA0 SIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRS
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KA0 SSHLDPAGTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSHLDPAGTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEP
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KA0 RVVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTV
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KA0 EEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDIL
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KA0 YVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTL
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KA0 SAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALR
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KA0 PVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDV
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KA0 TTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDK
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910
pF1KA0 VTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
1860 1870 1880 1890 1900 1910
>>XP_011538643 (OMIM: 604090) PREDICTED: disks large hom (1860 aa)
initn: 12016 init1: 12016 opt: 12025 Z-score: 5099.8 bits: 957.0 E(85289): 0
Smith-Waterman score: 12025; 99.8% identity (99.9% similar) in 1823 aa overlap (97-1919:39-1860)
70 80 90 100 110 120
pF1KA0 HFQDLRAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGT
:..: :::::::::::::::::::::::::
XP_011 VTLPWLGPRGQSGLQGQGRGTERVAWPVDSPSQG-GSTYSVLSTMPSDSESSSSLSSVGT
10 20 30 40 50 60
130 140 150 160 170 180
pF1KA0 TGKAPSPPPLLTDRQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRPYHRLNP
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRPYHRLNP
70 80 90 100 110 120
190 200 210 220 230 240
pF1KA0 DYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDM
130 140 150 160 170 180
250 260 270 280 290 300
pF1KA0 LRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTA
190 200 210 220 230 240
310 320 330 340 350 360
pF1KA0 MDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQ
250 260 270 280 290 300
370 380 390 400 410 420
pF1KA0 HQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERD
310 320 330 340 350 360
430 440 450 460 470 480
pF1KA0 AVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTM
370 380 390 400 410 420
490 500 510 520 530 540
pF1KA0 DAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDN
430 440 450 460 470 480
550 560 570 580 590 600
pF1KA0 LRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHD
490 500 510 520 530 540
610 620 630 640 650 660
pF1KA0 SAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIAD
550 560 570 580 590 600
670 680 690 700 710 720
pF1KA0 GRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLSG
610 620 630 640 650 660
730 740 750 760 770 780
pF1KA0 QKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQD
670 680 690 700 710 720
790 800 810 820 830 840
pF1KA0 SLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDI
730 740 750 760 770 780
850 860 870 880 890 900
pF1KA0 FYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGFG
790 800 810 820 830 840
910 920 930 940 950 960
pF1KA0 LVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVYKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVYKK
850 860 870 880 890 900
970 980 990 1000 1010 1020
pF1KA0 PKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQH
910 920 930 940 950 960
1030 1040 1050 1060 1070 1080
pF1KA0 RLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDSS
970 980 990 1000 1010 1020
1090 1100 1110 1120 1130 1140
pF1KA0 HLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVPASGELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVPASGELS
1030 1040 1050 1060 1070 1080
1150 1160 1170 1180 1190 1200
pF1KA0 PELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVGP
1090 1100 1110 1120 1130 1140
1210 1220 1230 1240 1250 1260
pF1KA0 CSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSARLGSSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSARLGSSSN
1150 1160 1170 1180 1190 1200
1270 1280 1290 1300 1310 1320
pF1KA0 LQFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQTSASTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQTSASTLP
1210 1220 1230 1240 1250 1260
1330 1340 1350 1360 1370 1380
pF1KA0 RIAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQA
1270 1280 1290 1300 1310 1320
1390 1400 1410 1420 1430 1440
pF1KA0 GLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLDP
1330 1340 1350 1360 1370 1380
1450 1460 1470 1480 1490 1500
pF1KA0 AGTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFIK
1390 1400 1410 1420 1430 1440
1510 1520 1530 1540 1550 1560
pF1KA0 KSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVE
1450 1460 1470 1480 1490 1500
1570 1580 1590 1600 1610 1620
pF1KA0 MLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDTL
1510 1520 1530 1540 1550 1560
1630 1640 1650 1660 1670 1680
pF1KA0 PQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARR
1570 1580 1590 1600 1610 1620
1690 1700 1710 1720 1730 1740
pF1KA0 SFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLILG
1630 1640 1650 1660 1670 1680
1750 1760 1770 1780 1790 1800
pF1KA0 PLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASI
1690 1700 1710 1720 1730 1740
1810 1820 1830 1840 1850 1860
pF1KA0 KEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHS
1750 1760 1770 1780 1790 1800
1870 1880 1890 1900 1910
pF1KA0 KEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
1810 1820 1830 1840 1850 1860
>>XP_011538644 (OMIM: 604090) PREDICTED: disks large hom (1829 aa)
initn: 12018 init1: 12018 opt: 12018 Z-score: 5097.0 bits: 956.4 E(85289): 0
Smith-Waterman score: 12018; 99.8% identity (99.9% similar) in 1822 aa overlap (98-1919:8-1829)
70 80 90 100 110 120
pF1KA0 FQDLRAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTT
: ..::::::::::::::::::::::::::
XP_011 MSWWTECAVSTGSTYSVLSTMPSDSESSSSLSSVGTT
10 20 30
130 140 150 160 170 180
pF1KA0 GKAPSPPPLLTDRQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRPYHRLNPD
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRPYHRLNPD
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA0 YERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDML
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA0 RRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAM
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA0 DKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQH
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA0 QCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDA
280 290 300 310 320 330
430 440 450 460 470 480
pF1KA0 VYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMD
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA0 AGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNL
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA0 RRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDS
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA0 AIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADG
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 RLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLSGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLSGQ
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 KDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDS
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 LTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDIF
700 710 720 730 740 750
850 860 870 880 890 900
pF1KA0 YTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGFGL
760 770 780 790 800 810
910 920 930 940 950 960
pF1KA0 VDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVYKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVYKKP
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KA0 KQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQHR
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KA0 LETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDSSH
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KA0 LPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVPASGELSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVPASGELSP
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KA0 ELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVGPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVGPC
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KA0 SSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSARLGSSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSARLGSSSNL
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KA0 QFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQTSASTLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQTSASTLPR
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KA0 IAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQAG
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420 1430 1440
pF1KA0 LEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLDPA
1300 1310 1320 1330 1340 1350
1450 1460 1470 1480 1490 1500
pF1KA0 GTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFIKK
1360 1370 1380 1390 1400 1410
1510 1520 1530 1540 1550 1560
pF1KA0 SQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEM
1420 1430 1440 1450 1460 1470
1570 1580 1590 1600 1610 1620
pF1KA0 LKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDTLP
1480 1490 1500 1510 1520 1530
1630 1640 1650 1660 1670 1680
pF1KA0 QGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRS
1540 1550 1560 1570 1580 1590
1690 1700 1710 1720 1730 1740
pF1KA0 FFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLILGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLILGP
1600 1610 1620 1630 1640 1650
1750 1760 1770 1780 1790 1800
pF1KA0 LLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIK
1660 1670 1680 1690 1700 1710
1810 1820 1830 1840 1850 1860
pF1KA0 EITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSK
1720 1730 1740 1750 1760 1770
1870 1880 1890 1900 1910
pF1KA0 EQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
1780 1790 1800 1810 1820
>>XP_016872402 (OMIM: 604090) PREDICTED: disks large hom (1825 aa)
initn: 12016 init1: 12016 opt: 12016 Z-score: 5096.1 bits: 956.3 E(85289): 0
Smith-Waterman score: 12016; 99.9% identity (100.0% similar) in 1818 aa overlap (102-1919:8-1825)
80 90 100 110 120 130
pF1KA0 RAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAP
::::::::::::::::::::::::::::::
XP_016 MGTYIELGSTYSVLSTMPSDSESSSSLSSVGTTGKAP
10 20 30
140 150 160 170 180 190
pF1KA0 SPPPLLTDRQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRPYHRLNPDYERL
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRPYHRLNPDYERL
40 50 60 70 80 90
200 210 220 230 240 250
pF1KA0 KIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRREN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRREN
100 110 120 130 140 150
260 270 280 290 300 310
pF1KA0 GQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLE
160 170 180 190 200 210
320 330 340 350 360 370
pF1KA0 VVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCAL
220 230 240 250 260 270
380 390 400 410 420 430
pF1KA0 SLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSE
280 290 300 310 320 330
440 450 460 470 480 490
pF1KA0 YKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRA
340 350 360 370 380 390
500 510 520 530 540 550
pF1KA0 NKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRER
400 410 420 430 440 450
560 570 580 590 600 610
pF1KA0 DRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDT
460 470 480 490 500 510
620 630 640 650 660 670
pF1KA0 DSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRV
520 530 540 550 560 570
680 690 700 710 720 730
pF1KA0 NDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLSGQKDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLSGQKDSG
580 590 600 610 620 630
740 750 760 770 780 790
pF1KA0 ISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLS
640 650 660 670 680 690
800 810 820 830 840 850
pF1KA0 LLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDIFYTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDIFYTDR
700 710 720 730 740 750
860 870 880 890 900 910
pF1KA0 LEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGFGLVDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGFGLVDVR
760 770 780 790 800 810
920 930 940 950 960 970
pF1KA0 GRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVYKKPKQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVYKKPKQRK
820 830 840 850 860 870
980 990 1000 1010 1020 1030
pF1KA0 SIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQHRLETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQHRLETS
880 890 900 910 920 930
1040 1050 1060 1070 1080 1090
pF1KA0 SESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDSSHLPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDSSHLPAK
940 950 960 970 980 990
1100 1110 1120 1130 1140 1150
pF1KA0 KSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVPASGELSPELQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVPASGELSPELQE
1000 1010 1020 1030 1040 1050
1160 1170 1180 1190 1200 1210
pF1KA0 WAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPP
1060 1070 1080 1090 1100 1110
1220 1230 1240 1250 1260 1270
pF1KA0 AARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSARLGSSSNLQFKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSARLGSSSNLQFKA
1120 1130 1140 1150 1160 1170
1280 1290 1300 1310 1320 1330
pF1KA0 ERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQTSASTLPRIAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQTSASTLPRIAVN
1180 1190 1200 1210 1220 1230
1340 1350 1360 1370 1380 1390
pF1KA0 PASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQAGLEYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQAGLEYG
1240 1250 1260 1270 1280 1290
1400 1410 1420 1430 1440 1450
pF1KA0 DQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLDPAGTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLDPAGTHS
1300 1310 1320 1330 1340 1350
1460 1470 1480 1490 1500 1510
pF1KA0 TLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFIKKSQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFIKKSQLE
1360 1370 1380 1390 1400 1410
1520 1530 1540 1550 1560 1570
pF1KA0 LGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPR
1420 1430 1440 1450 1460 1470
1580 1590 1600 1610 1620 1630
pF1KA0 DGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDTLPQGTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDTLPQGTF
1480 1490 1500 1510 1520 1530
1640 1650 1660 1670 1680 1690
pF1KA0 GSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRR
1540 1550 1560 1570 1580 1590
1700 1710 1720 1730 1740 1750
pF1KA0 KHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLILGPLLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLILGPLLDV
1600 1610 1620 1630 1640 1650
1760 1770 1780 1790 1800 1810
pF1KA0 VKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITE
1660 1670 1680 1690 1700 1710
1820 1830 1840 1850 1860 1870
pF1KA0 KNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFE
1720 1730 1740 1750 1760 1770
1880 1890 1900 1910
pF1KA0 AAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
1780 1790 1800 1810 1820
>>XP_016872403 (OMIM: 604090) PREDICTED: disks large hom (1809 aa)
initn: 11965 init1: 11965 opt: 11965 Z-score: 5074.6 bits: 952.3 E(85289): 0
Smith-Waterman score: 11965; 99.9% identity (100.0% similar) in 1809 aa overlap (111-1919:1-1809)
90 100 110 120 130 140
pF1KA0 HLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDR
:::::::::::::::::::::::::::::.
XP_016 MPSDSESSSSLSSVGTTGKAPSPPPLLTDQ
10 20 30
150 160 170 180 190 200
pF1KA0 QVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRPYHRLNPDYERLKIQCVRAMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRPYHRLNPDYERLKIQCVRAMS
40 50 60 70 80 90
210 220 230 240 250 260
pF1KA0 DLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNL
100 110 120 130 140 150
270 280 290 300 310 320
pF1KA0 LQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDAL
160 170 180 190 200 210
330 340 350 360 370 380
pF1KA0 RKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCALSLRRFEAIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCALSLRRFEAIH
220 230 240 250 260 270
390 400 410 420 430 440
pF1KA0 HELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERD
280 290 300 310 320 330
450 460 470 480 490 500
pF1KA0 QVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRK
340 350 360 370 380 390
510 520 530 540 550 560
pF1KA0 QCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAE
400 410 420 430 440 450
570 580 590 600 610 620
pF1KA0 ALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEV
460 470 480 490 500 510
630 640 650 660 670 680
pF1KA0 VEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRIND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRIND
520 530 540 550 560 570
690 700 710 720 730 740
pF1KA0 VDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYA
580 590 600 610 620 630
750 760 770 780 790 800
pF1KA0 AAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSS
640 650 660 670 680 690
810 820 830 840 850 860
pF1KA0 SWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDIFYTDRLEDRKEPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDIFYTDRLEDRKEPGP
700 710 720 730 740 750
870 880 890 900 910 920
pF1KA0 PGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGFGLVDVRGRRPLLPFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGFGLVDVRGRRPLLPFE
760 770 780 790 800 810
930 940 950 960 970 980
pF1KA0 TEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVYKKPKQRKSIFDPNTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVYKKPKQRKSIFDPNTFK
820 830 840 850 860 870
990 1000 1010 1020 1030 1040
pF1KA0 RPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQHRLETSSESEATLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQHRLETSSESEATLVG
880 890 900 910 920 930
1050 1060 1070 1080 1090 1100
pF1KA0 SSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDSSHLPAKKSCDEDLTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDSSHLPAKKSCDEDLTS
940 950 960 970 980 990
1110 1120 1130 1140 1150 1160
pF1KA0 QKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVPASGELSPELQEWAPYSPGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVPASGELSPELQEWAPYSPGHS
1000 1010 1020 1030 1040 1050
1170 1180 1190 1200 1210 1220
pF1KA0 SRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPPAARDAGPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPPAARDAGPQG
1060 1070 1080 1090 1100 1110
1230 1240 1250 1260 1270 1280
pF1KA0 LHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTP
1120 1130 1140 1150 1160 1170
1290 1300 1310 1320 1330 1340
pF1KA0 RYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQTSASTLPRIAVNPASLGERRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQTSASTLPRIAVNPASLGERRK
1180 1190 1200 1210 1220 1230
1350 1360 1370 1380 1390 1400
pF1KA0 DRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQAGLEYGDQLLEFNGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQAGLEYGDQLLEFNGI
1240 1250 1260 1270 1280 1290
1410 1420 1430 1440 1450 1460
pF1KA0 NLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLDPAGTHSTLQGSGTTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLDPAGTHSTLQGSGTTT
1300 1310 1320 1330 1340 1350
1470 1480 1490 1500 1510 1520
pF1KA0 PEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGGN
1360 1370 1380 1390 1400 1410
1530 1540 1550 1560 1570 1580
pF1KA0 LHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQY
1420 1430 1440 1450 1460 1470
1590 1600 1610 1620 1630 1640
pF1KA0 RPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDTLPQGTFGSWMAWQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDTLPQGTFGSWMAWQLD
1480 1490 1500 1510 1520 1530
1650 1660 1670 1680 1690 1700
pF1KA0 ENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKHKRSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKHKRSGS
1540 1550 1560 1570 1580 1590
1710 1720 1730 1740 1750 1760
pF1KA0 KDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVKEMLVNEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVKEMLVNEA
1600 1610 1620 1630 1640 1650
1770 1780 1790 1800 1810 1820
pF1KA0 PGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDI
1660 1670 1680 1690 1700 1710
1830 1840 1850 1860 1870 1880
pF1KA0 APHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEY
1720 1730 1740 1750 1760 1770
1890 1900 1910
pF1KA0 SRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
:::::::::::::::::::::::::::::::::::::::
XP_016 SRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
1780 1790 1800
>>XP_011538646 (OMIM: 604090) PREDICTED: disks large hom (1807 aa)
initn: 11884 init1: 11884 opt: 11884 Z-score: 5040.4 bits: 946.0 E(85289): 0
Smith-Waterman score: 11884; 99.9% identity (100.0% similar) in 1795 aa overlap (125-1919:13-1807)
100 110 120 130 140 150
pF1KA0 PQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDRQVNEKVENLSIQLR
:::::::::::::::.::::::::::::::
XP_011 MQGSRPKQSHPGGTTGKAPSPPPLLTDQQVNEKVENLSIQLR
10 20 30 40
160 170 180 190 200 210
pF1KA0 LMTRERNELRKRLAFATHGTAFDKRPYHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMTRERNELRKRLAFATHGTAFDKRPYHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALK
50 60 70 80 90 100
220 230 240 250 260 270
pF1KA0 RCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKRLHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKRLHEE
110 120 130 140 150 160
280 290 300 310 320 330
pF1KA0 DQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNAD
170 180 190 200 210 220
340 350 360 370 380 390
pF1KA0 LSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQ
230 240 250 260 270 280
400 410 420 430 440 450
pF1KA0 WEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQTEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQTEVE
290 300 310 320 330 340
460 470 480 490 500 510
pF1KA0 LAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQ
350 360 370 380 390 400
520 530 540 550 560 570
pF1KA0 EADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKND
410 420 430 440 450 460
580 590 600 610 620 630
pF1KA0 VSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDIDLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDIDLKA
470 480 490 500 510 520
640 650 660 670 680 690
pF1KA0 LGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKA
530 540 550 560 570 580
700 710 720 730 740 750
pF1KA0 LLNGEGAINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVLPGSPAAKEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLNGEGAINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVLPGSPAAKEGS
590 600 610 620 630 640
760 770 780 790 800 810
pF1KA0 LAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDS
650 660 670 680 690 700
820 830 840 850 860 870
pF1KA0 DKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPG
710 720 730 740 750 760
880 890 900 910 920 930
pF1KA0 GPLQVCPQACPSASERSLSSFRSDASGDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLQVCPQACPSASERSLSSFRSDASGDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLD
770 780 790 800 810 820
940 950 960 970 980 990
pF1KA0 KADSEGSNSGGTWPKAMLSSTAVPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KADSEGSNSGGTWPKAMLSSTAVPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPG
830 840 850 860 870 880
1000 1010 1020 1030 1040 1050
pF1KA0 PGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSALPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSALPPD
890 900 910 920 930 940
1060 1070 1080 1090 1100 1110
pF1KA0 VDPGEPMHASPPRKARVRIASSYYPEGDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDPGEPMHASPPRKARVRIASSYYPEGDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPK
950 960 970 980 990 1000
1120 1130 1140 1150 1160 1170
pF1KA0 SAPSFRPKLAPVVIPAQFLEEQKCVPASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAPSFRPKLAPVVIPAQFLEEQKCVPASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPS
1010 1020 1030 1040 1050 1060
1180 1190 1200 1210 1220 1230
pF1KA0 VGTVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGTVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLD
1070 1080 1090 1100 1110 1120
1240 1250 1260 1270 1280 1290
pF1KA0 LSHRTCSDYSEMRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSHRTCSDYSEMRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSV
1130 1140 1150 1160 1170 1180
1300 1310 1320 1330 1340 1350
pF1KA0 SHSECSTPPQSPLNIDTLSSCSQSQTSASTLPRIAVNPASLGERRKDRPYVEEPRHVKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHSECSTPPQSPLNIDTLSSCSQSQTSASTLPRIAVNPASLGERRKDRPYVEEPRHVKVQ
1190 1200 1210 1220 1230 1240
1360 1370 1380 1390 1400 1410
pF1KA0 KGSEPLGISIVSGEKGGIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSEPLGISIVSGEKGGIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLII
1250 1260 1270 1280 1290 1300
1420 1430 1440 1450 1460 1470
pF1KA0 GQQCDTITILAQYNPHVHQLSSHSRSSSHLDPAGTHSTLQGSGTTTPEHPSVIDPLMEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQQCDTITILAQYNPHVHQLSSHSRSSSHLDPAGTHSTLQGSGTTTPEHPSVIDPLMEQD
1310 1320 1330 1340 1350 1360
1480 1490 1500 1510 1520 1530
pF1KA0 EGPSTPPAKQSSSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGPSTPPAKQSSSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSP
1370 1380 1390 1400 1410 1420
1540 1550 1560 1570 1580 1590
pF1KA0 AKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGD
1430 1440 1450 1460 1470 1480
1600 1610 1620 1630 1640 1650
pF1KA0 SFYIRALYDRLADVEQELSFKKDDILYVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFYIRALYDRLADVEQELSFKKDDILYVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSK
1490 1500 1510 1520 1530 1540
1660 1670 1680 1690 1700 1710
pF1KA0 YVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSS
1550 1560 1570 1580 1590 1600
1720 1730 1740 1750 1760 1770
pF1KA0 DSIPLFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSIPLFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKA
1610 1620 1630 1640 1650 1660
1780 1790 1800 1810 1820 1830
pF1KA0 SQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIY
1670 1680 1690 1700 1710 1720
1840 1850 1860 1870 1880 1890
pF1KA0 PIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALS
1730 1740 1750 1760 1770 1780
1900 1910
pF1KA0 SICTQILAMVNQEQNKVLWIPACPL
:::::::::::::::::::::::::
XP_011 SICTQILAMVNQEQNKVLWIPACPL
1790 1800
>>XP_011538647 (OMIM: 604090) PREDICTED: disks large hom (1764 aa)
initn: 11690 init1: 11690 opt: 11690 Z-score: 4958.6 bits: 930.8 E(85289): 0
Smith-Waterman score: 11690; 100.0% identity (100.0% similar) in 1764 aa overlap (156-1919:1-1764)
130 140 150 160 170 180
pF1KA0 TTGKAPSPPPLLTDRQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRPYHRLN
::::::::::::::::::::::::::::::
XP_011 MTRERNELRKRLAFATHGTAFDKRPYHRLN
10 20 30
190 200 210 220 230 240
pF1KA0 PDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVD
40 50 60 70 80 90
250 260 270 280 290 300
pF1KA0 MLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDT
100 110 120 130 140 150
310 320 330 340 350 360
pF1KA0 AMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQL
160 170 180 190 200 210
370 380 390 400 410 420
pF1KA0 QHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREER
220 230 240 250 260 270
430 440 450 460 470 480
pF1KA0 DAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVT
280 290 300 310 320 330
490 500 510 520 530 540
pF1KA0 MDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCD
340 350 360 370 380 390
550 560 570 580 590 600
pF1KA0 NLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSH
400 410 420 430 440 450
610 620 630 640 650 660
pF1KA0 DSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIA
460 470 480 490 500 510
670 680 690 700 710 720
pF1KA0 DGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLS
520 530 540 550 560 570
730 740 750 760 770 780
pF1KA0 GQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQ
580 590 600 610 620 630
790 800 810 820 830 840
pF1KA0 DSLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTD
640 650 660 670 680 690
850 860 870 880 890 900
pF1KA0 IFYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGF
700 710 720 730 740 750
910 920 930 940 950 960
pF1KA0 GLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVYK
760 770 780 790 800 810
970 980 990 1000 1010 1020
pF1KA0 KPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSDSIKFQ
820 830 840 850 860 870
1030 1040 1050 1060 1070 1080
pF1KA0 HRLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDS
880 890 900 910 920 930
1090 1100 1110 1120 1130 1140
pF1KA0 SHLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVPASGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVPASGEL
940 950 960 970 980 990
1150 1160 1170 1180 1190 1200
pF1KA0 SPELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVG
1000 1010 1020 1030 1040 1050
1210 1220 1230 1240 1250 1260
pF1KA0 PCSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSARLGSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSARLGSSS
1060 1070 1080 1090 1100 1110
1270 1280 1290 1300 1310 1320
pF1KA0 NLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQTSASTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQTSASTL
1120 1130 1140 1150 1160 1170
1330 1340 1350 1360 1370 1380
pF1KA0 PRIAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRIAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQ
1180 1190 1200 1210 1220 1230
1390 1400 1410 1420 1430 1440
pF1KA0 AGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLD
1240 1250 1260 1270 1280 1290
1450 1460 1470 1480 1490 1500
pF1KA0 PAGTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAGTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFI
1300 1310 1320 1330 1340 1350
1510 1520 1530 1540 1550 1560
pF1KA0 KKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYV
1360 1370 1380 1390 1400 1410
1570 1580 1590 1600 1610 1620
pF1KA0 EMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDT
1420 1430 1440 1450 1460 1470
1630 1640 1650 1660 1670 1680
pF1KA0 LPQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAAR
1480 1490 1500 1510 1520 1530
1690 1700 1710 1720 1730 1740
pF1KA0 RSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLIL
1540 1550 1560 1570 1580 1590
1750 1760 1770 1780 1790 1800
pF1KA0 GPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVAS
1600 1610 1620 1630 1640 1650
1810 1820 1830 1840 1850 1860
pF1KA0 IKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRH
1660 1670 1680 1690 1700 1710
1870 1880 1890 1900 1910
pF1KA0 SKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
1720 1730 1740 1750 1760
>>XP_011538648 (OMIM: 604090) PREDICTED: disks large hom (1680 aa)
initn: 10924 init1: 10924 opt: 10924 Z-score: 4635.2 bits: 870.9 E(85289): 0
Smith-Waterman score: 10924; 99.9% identity (100.0% similar) in 1656 aa overlap (1-1656:1-1656)
10 20 30 40 50 60
pF1KA0 MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LAKERDHFQDLRAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKERDHFQDLRAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LSSVGTTGKAPSPPPLLTDRQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_011 LSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KDDVDMLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDDVDMLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 KLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 YREERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YREERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 AHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 HINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 LRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 STQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDAS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKRAGPLTPPKPPRRSD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SIKFQHRLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIKFQHRLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 GDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 ASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 SHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYSEMRATHGSNSLPSSAR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNIDTLSSCSQSQT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 SASTLPRIAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SASTLPRIAVNPASLGERRKDRPYVEEPRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVG
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 SIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 SSHLDPAGTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSHLDPAGTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 RVVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTV
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 EEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDIL
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 YVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTL
::::::::::::::::::::::::::::::::::::
XP_011 YVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYVKRNSSCHQLKAVLAVPFDTELNML
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 SAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALR
>>XP_016872404 (OMIM: 604090) PREDICTED: disks large hom (1613 aa)
initn: 10688 init1: 10688 opt: 10688 Z-score: 4535.7 bits: 852.4 E(85289): 0
Smith-Waterman score: 10688; 100.0% identity (100.0% similar) in 1613 aa overlap (307-1919:1-1613)
280 290 300 310 320 330
pF1KA0 KEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLS
::::::::::::::::::::::::::::::
XP_016 MDKLEVVKKDYDALRKRYSEKVAIHNADLS
10 20 30
340 350 360 370 380 390
pF1KA0 RLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWE
40 50 60 70 80 90
400 410 420 430 440 450
pF1KA0 MELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQTEVELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQTEVELA
100 110 120 130 140 150
460 470 480 490 500 510
pF1KA0 ESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEA
160 170 180 190 200 210
520 530 540 550 560 570
pF1KA0 DVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVS
220 230 240 250 260 270
580 590 600 610 620 630
pF1KA0 RELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALG
280 290 300 310 320 330
640 650 660 670 680 690
pF1KA0 FDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALL
340 350 360 370 380 390
700 710 720 730 740 750
pF1KA0 NGEGAINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGEGAINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLA
400 410 420 430 440 450
760 770 780 790 800 810
pF1KA0 VGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDK
460 470 480 490 500 510
820 830 840 850 860 870
pF1KA0 MLSFRAHGPEVQAHNKRNLIQHNNSTQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSFRAHGPEVQAHNKRNLIQHNNSTQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPGGP
520 530 540 550 560 570
880 890 900 910 920 930
pF1KA0 LQVCPQACPSASERSLSSFRSDASGDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLDKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQVCPQACPSASERSLSSFRSDASGDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLDKA
580 590 600 610 620 630
940 950 960 970 980 990
pF1KA0 DSEGSNSGGTWPKAMLSSTAVPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSEGSNSGGTWPKAMLSSTAVPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPG
640 650 660 670 680 690
1000 1010 1020 1030 1040 1050
pF1KA0 PAHSPQPSKRAGPLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSALPPDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAHSPQPSKRAGPLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSALPPDVD
700 710 720 730 740 750
1060 1070 1080 1090 1100 1110
pF1KA0 PGEPMHASPPRKARVRIASSYYPEGDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGEPMHASPPRKARVRIASSYYPEGDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPKSA
760 770 780 790 800 810
1120 1130 1140 1150 1160 1170
pF1KA0 PSFRPKLAPVVIPAQFLEEQKCVPASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSFRPKLAPVVIPAQFLEEQKCVPASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVG
820 830 840 850 860 870
1180 1190 1200 1210 1220 1230
pF1KA0 TVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLDLS
880 890 900 910 920 930
1240 1250 1260 1270 1280 1290
pF1KA0 HRTCSDYSEMRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRTCSDYSEMRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSH
940 950 960 970 980 990
1300 1310 1320 1330 1340 1350
pF1KA0 SECSTPPQSPLNIDTLSSCSQSQTSASTLPRIAVNPASLGERRKDRPYVEEPRHVKVQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SECSTPPQSPLNIDTLSSCSQSQTSASTLPRIAVNPASLGERRKDRPYVEEPRHVKVQKG
1000 1010 1020 1030 1040 1050
1360 1370 1380 1390 1400 1410
pF1KA0 SEPLGISIVSGEKGGIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEPLGISIVSGEKGGIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQ
1060 1070 1080 1090 1100 1110
1420 1430 1440 1450 1460 1470
pF1KA0 QCDTITILAQYNPHVHQLSSHSRSSSHLDPAGTHSTLQGSGTTTPEHPSVIDPLMEQDEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCDTITILAQYNPHVHQLSSHSRSSSHLDPAGTHSTLQGSGTTTPEHPSVIDPLMEQDEG
1120 1130 1140 1150 1160 1170
1480 1490 1500 1510 1520 1530
pF1KA0 PSTPPAKQSSSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTPPAKQSSSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAK
1180 1190 1200 1210 1220 1230
1540 1550 1560 1570 1580 1590
pF1KA0 GPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSF
1240 1250 1260 1270 1280 1290
1600 1610 1620 1630 1640 1650
pF1KA0 YIRALYDRLADVEQELSFKKDDILYVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIRALYDRLADVEQELSFKKDDILYVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYV
1300 1310 1320 1330 1340 1350
1660 1670 1680 1690 1700 1710
pF1KA0 MDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDS
1360 1370 1380 1390 1400 1410
1720 1730 1740 1750 1760 1770
pF1KA0 IPLFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPLFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQ
1420 1430 1440 1450 1460 1470
1780 1790 1800 1810 1820 1830
pF1KA0 QAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPI
1480 1490 1500 1510 1520 1530
1840 1850 1860 1870 1880 1890
pF1KA0 VIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSI
1540 1550 1560 1570 1580 1590
1900 1910
pF1KA0 CTQILAMVNQEQNKVLWIPACPL
:::::::::::::::::::::::
XP_016 CTQILAMVNQEQNKVLWIPACPL
1600 1610
1919 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:47:39 2016 done: Thu Nov 3 09:47:42 2016
Total Scan time: 22.120 Total Display time: 1.370
Function used was FASTA [36.3.4 Apr, 2011]