FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0586, 1533 aa 1>>>pF1KA0586 1533 - 1533 aa - 1533 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.1392+/-0.000451; mu= -3.8977+/- 0.028 mean_var=287.8167+/-59.022, 0's: 0 Z-trim(119.3): 21 B-trim: 516 in 1/56 Lambda= 0.075599 statistics sampled from 33133 (33154) to 33133 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.389), width: 16 Scan time: 16.480 The best scores are: opt bits E(85289) NP_001231119 (OMIM: 610178,616490,616546) protein (1533) 9979 1103.2 0 NP_001316872 (OMIM: 610178,616490,616546) protein (1548) 9979 1103.2 0 NP_001316873 (OMIM: 610178,616490,616546) protein (1591) 9665 1069.0 0 NP_001231120 (OMIM: 610178,616490,616546) protein (1463) 9509 1052.0 0 NP_001316875 (OMIM: 610178,616490,616546) protein (1526) 9505 1051.5 0 NP_001231121 (OMIM: 610178,616490,616546) protein (1504) 9188 1017.0 0 NP_001316874 (OMIM: 610178,616490,616546) protein (1441) 9035 1000.3 0 NP_001231118 (OMIM: 610178,616490,616546) protein (1644) 8874 982.7 0 NP_001231122 (OMIM: 610178,616490,616546) protein (1347) 8699 963.6 0 NP_001316876 (OMIM: 610178,616490,616546) protein (1504) 8261 915.9 0 NP_055564 (OMIM: 610178,616490,616546) protein TAL (1472) 6074 677.3 2.4e-193 >>NP_001231119 (OMIM: 610178,616490,616546) protein TALP (1533 aa) initn: 9979 init1: 9979 opt: 9979 Z-score: 5893.6 bits: 1103.2 E(85289): 0 Smith-Waterman score: 9979; 99.9% identity (99.9% similar) in 1533 aa overlap (1-1533:1-1533) 10 20 30 40 50 60 pF1KA0 MPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTSLNGTSRGSSDLTSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTSLNGTSRGSSDLTSAR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 NCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVAAATAAAIATAAPLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVAAATAAAIATAAPLIK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHCHDHEKQMNVFMEQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHCHDHEKQMNVFMEQHI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 RHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKPEHPNLGSCNPSLYNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKPEHPNLGSCNPSLYNT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKRENLLEEKENMEVSCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKRENLLEEKENMEVSCH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 RGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFPSCEELETTKVTMQKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFPSCEELETTKVTMQKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 DDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTTRSVLKDAEKILRGVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTTRSVLKDAEKILRGVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 NNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKHSQKQIEEHFRNLPMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKHSQKQIEEHFRNLPMR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLKKGPYLRFNSPSPKSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLKKGPYLRFNSPSPKSR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 PQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPHGDQQYLFSPSREMPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPHGDQQYLFSPSREMPT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 FSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSIPPSSRKVETGVKKPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSIPPSSRKVETGVKKPN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 IAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKEASPPPVQTWIKTPEI ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: NP_001 IAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKEASLPPVQTWIKTPEI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 MKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVKADSTKYNGPPFPPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVKADSTKYNGPPFPPVA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 STFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQQIAPSISVSVSETSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQQIAPSISVSVSETSE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 PLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVMLGDREAKKQGPVATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVMLGDREAKKQGPVATG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 VSGDASTNETYLPARVCTPLATPQPTPPCSPSSPAKECVLVKTPDSSPCDSDHDMAFPVK :::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::: NP_001 VSGDASTNETYLPARVCTPLPTPQPTPPCSPSSPAKECVLVKTPDSSPCDSDHDMAFPVK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 EICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDKLKVSSPELPKPWGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDKLKVSSPELPKPWGDG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 DLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEPVPFMPFPAGTKAPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEPVPFMPFPAGTKAPSP 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 SQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPKILEDIGLYLTNLNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPKILEDIGLYLTNLNDS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 LSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESAVSQQAVYHSEDLENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESAVSQQAVYHSEDLENS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 VGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKPLSRQFDTVSGSIYED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKPLSRQFDTVSGSIYED 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 SCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFSQYQLKQNQDVKQVEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFSQYQLKQNQDVKQVEH 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 KPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGGKAVPLSASQMPPAKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGGKAVPLSASQMPPAKM 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KA0 SVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF ::::::::::::::::::::::::::::::::: NP_001 SVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF 1510 1520 1530 >>NP_001316872 (OMIM: 610178,616490,616546) protein TALP (1548 aa) initn: 9979 init1: 9979 opt: 9979 Z-score: 5893.5 bits: 1103.2 E(85289): 0 Smith-Waterman score: 9979; 99.9% identity (99.9% similar) in 1533 aa overlap (1-1533:16-1548) 10 20 30 40 pF1KA0 MPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTS ::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 LNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFIS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 QYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVA 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 AATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHC 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 HDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 EHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKR 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 ENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFP 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 SCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTT 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 RSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTV 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 DEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKH 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 SQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLK 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 KGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPH 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 GDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSI 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 PPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKE 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 ASPPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVK :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASLPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVK 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 ADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQ 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 QIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVM 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA0 LGDREAKKQGPVATGVSGDASTNETYLPARVCTPLATPQPTPPCSPSSPAKECVLVKTPD ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: NP_001 LGDREAKKQGPVATGVSGDASTNETYLPARVCTPLPTPQPTPPCSPSSPAKECVLVKTPD 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA0 SSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDK 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA0 LKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEP 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA0 VPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPK 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA0 ILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESA 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA0 VSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA0 LSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFS 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA0 QYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGG 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 pF1KA0 KAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF 1510 1520 1530 1540 >>NP_001316873 (OMIM: 610178,616490,616546) protein TALP (1591 aa) initn: 9665 init1: 9665 opt: 9665 Z-score: 5708.2 bits: 1069.0 E(85289): 0 Smith-Waterman score: 9665; 99.9% identity (99.9% similar) in 1484 aa overlap (1-1484:16-1499) 10 20 30 40 pF1KA0 MPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTS ::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 LNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFIS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 QYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVA 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 AATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHC 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 HDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 EHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKR 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 ENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFP 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 SCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTT 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 RSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTV 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 DEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKH 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 SQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLK 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 KGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPH 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 GDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSI 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 PPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKE 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 ASPPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVK :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASLPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVK 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 ADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQ 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 QIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVM 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA0 LGDREAKKQGPVATGVSGDASTNETYLPARVCTPLATPQPTPPCSPSSPAKECVLVKTPD ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: NP_001 LGDREAKKQGPVATGVSGDASTNETYLPARVCTPLPTPQPTPPCSPSSPAKECVLVKTPD 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA0 SSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDK 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA0 LKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEP 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA0 VPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPK 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA0 ILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESA 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA0 VSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA0 LSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFS 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA0 QYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGL 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 pF1KA0 KAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF NP_001 GVHVKKVSCIGKLGLWRFVIQIISSPRWESSATLRFTDAPCQDVSDAAVSEPRGLLSVSE 1510 1520 1530 1540 1550 1560 >>NP_001231120 (OMIM: 610178,616490,616546) protein TALP (1463 aa) initn: 9509 init1: 9509 opt: 9509 Z-score: 5616.8 bits: 1052.0 E(85289): 0 Smith-Waterman score: 9509; 99.9% identity (99.9% similar) in 1463 aa overlap (71-1533:1-1463) 50 60 70 80 90 100 pF1KA0 GTGTSLNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKAN :::::::::::::::::::::::::::::: NP_001 MVSESDFSKDVAVQVLPLDKIEENNKQKAN 10 20 30 110 120 130 140 150 160 pF1KA0 DIFISQYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIFISQYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDS 40 50 60 70 80 90 170 180 190 200 210 220 pF1KA0 ATTVAAATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATTVAAATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQ 100 110 120 130 140 150 230 240 250 260 270 280 pF1KA0 EKLHCHDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKLHCHDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEK 160 170 180 190 200 210 290 300 310 320 330 340 pF1KA0 YSVKPEHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSVKPEHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDD 220 230 240 250 260 270 350 360 370 380 390 400 pF1KA0 ELSKRENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELSKRENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEK 280 290 300 310 320 330 410 420 430 440 450 460 pF1KA0 TNRFPSCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNRFPSCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQ 340 350 360 370 380 390 470 480 490 500 510 520 pF1KA0 TTNTTRSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTNTTRSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIR 400 410 420 430 440 450 530 540 550 560 570 580 pF1KA0 IRKTVDEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRKTVDEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSV 460 470 480 490 500 510 590 600 610 620 630 640 pF1KA0 IPRKHSQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPRKHSQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGH 520 530 540 550 560 570 650 660 670 680 690 700 pF1KA0 RSTLKKGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSTLKKGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSV 580 590 600 610 620 630 710 720 730 740 750 760 pF1KA0 PVLPHGDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLPHGDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT 640 650 660 670 680 690 770 780 790 800 810 820 pF1KA0 VTTSIPPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTTSIPPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPL 700 710 720 730 740 750 830 840 850 860 870 880 pF1KA0 SSPKEASPPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEF ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSPKEASLPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEF 760 770 780 790 800 810 890 900 910 920 930 940 pF1KA0 NRSVKADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRSVKADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGL 820 830 840 850 860 870 950 960 970 980 990 1000 pF1KA0 FPVQQQIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPVQQQIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAE 880 890 900 910 920 930 1010 1020 1030 1040 1050 1060 pF1KA0 TIAVMLGDREAKKQGPVATGVSGDASTNETYLPARVCTPLATPQPTPPCSPSSPAKECVL :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 TIAVMLGDREAKKQGPVATGVSGDASTNETYLPARVCTPLPTPQPTPPCSPSSPAKECVL 940 950 960 970 980 990 1070 1080 1090 1100 1110 1120 pF1KA0 VKTPDSSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKTPDSSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSD 1000 1010 1020 1030 1040 1050 1130 1140 1150 1160 1170 1180 pF1KA0 ISIDKLKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISIDKLKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQP 1060 1070 1080 1090 1100 1110 1190 1200 1210 1220 1230 1240 pF1KA0 PPPEPVPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPEPVPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQ 1120 1130 1140 1150 1160 1170 1250 1260 1270 1280 1290 1300 pF1KA0 KLAPKILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLAPKILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQ 1180 1190 1200 1210 1220 1230 1310 1320 1330 1340 1350 1360 pF1KA0 NQESAVSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NQESAVSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQ 1240 1250 1260 1270 1280 1290 1370 1380 1390 1400 1410 1420 pF1KA0 CDPKPLSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CDPKPLSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVA 1300 1310 1320 1330 1340 1350 1430 1440 1450 1460 1470 1480 pF1KA0 AEDFSQYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEDFSQYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTC 1360 1370 1380 1390 1400 1410 1490 1500 1510 1520 1530 pF1KA0 VFSGGKAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFSGGKAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF 1420 1430 1440 1450 1460 >>NP_001316875 (OMIM: 610178,616490,616546) protein TALP (1526 aa) initn: 9813 init1: 9505 opt: 9505 Z-score: 5614.2 bits: 1051.5 E(85289): 0 Smith-Waterman score: 9773; 98.4% identity (98.4% similar) in 1533 aa overlap (1-1533:16-1526) 10 20 30 40 pF1KA0 MPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTS ::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 LNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFIS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 QYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVA 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 AATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHC 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 HDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 EHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKR 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 ENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFP 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 SCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTT 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 RSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTV 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 DEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKH 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 SQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLK 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 KGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPH 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 GDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSI 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 PPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKE 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 ASPPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVK :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASLPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVK 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 ADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQ 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 QIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVM 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA0 LGDREAKKQGPVATGVSGDASTNETYLPARVCTPLATPQPTPPCSPSSPAKECVLVKTPD ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: NP_001 LGDREAKKQGPVATGVSGDASTNETYLPARVCTPLPTPQPTPPCSPSSPAKECVLVKTPD 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA0 SSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDK 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA0 LKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEP 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA0 VPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPK 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA0 ILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESA 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA0 VSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA0 LSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFS 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA0 QYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGG :::::::::::::::::::::::::::::::::::: :: NP_001 QYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQ----------------------GG 1450 1460 1470 1490 1500 1510 1520 1530 pF1KA0 KAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF 1480 1490 1500 1510 1520 >>NP_001231121 (OMIM: 610178,616490,616546) protein TALP (1504 aa) initn: 9492 init1: 9188 opt: 9188 Z-score: 5427.4 bits: 1017.0 E(85289): 0 Smith-Waterman score: 9414; 97.1% identity (97.1% similar) in 1504 aa overlap (71-1533:1-1504) 50 60 70 80 90 100 pF1KA0 GTGTSLNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKAN :::::::::::::::::::::::::::::: NP_001 MVSESDFSKDVAVQVLPLDKIEENNKQKAN 10 20 30 110 120 pF1KA0 DIFISQYTMGQKDALRTVLKQ--------------------------------------- ::::::::::::::::::::: NP_001 DIFISQYTMGQKDALRTVLKQNVSLCLTGWSDHSGVITTHCSLYLLRLMRSSHLSLPSSW 40 50 60 70 80 90 130 140 150 160 170 pF1KA0 --KAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVAAATAAAIATAAPLI .::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYRAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVAAATAAAIATAAPLI 100 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 KVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHCHDHEKQMNVFMEQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHCHDHEKQMNVFMEQH 160 170 180 190 200 210 240 250 260 270 280 290 pF1KA0 IRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKPEHPNLGSCNPSLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKPEHPNLGSCNPSLYN 220 230 240 250 260 270 300 310 320 330 340 350 pF1KA0 TFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKRENLLEEKENMEVSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKRENLLEEKENMEVSC 280 290 300 310 320 330 360 370 380 390 400 410 pF1KA0 HRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFPSCEELETTKVTMQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFPSCEELETTKVTMQK 340 350 360 370 380 390 420 430 440 450 460 470 pF1KA0 SDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTTRSVLKDAEKILRGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTTRSVLKDAEKILRGV 400 410 420 430 440 450 480 490 500 510 520 530 pF1KA0 QNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDE 460 470 480 490 500 510 540 550 560 570 580 590 pF1KA0 LSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKHSQKQIEEHFRNLPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKHSQKQIEEHFRNLPM 520 530 540 550 560 570 600 610 620 630 640 650 pF1KA0 RGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLKKGPYLRFNSPSPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLKKGPYLRFNSPSPKS 580 590 600 610 620 630 660 670 680 690 700 710 pF1KA0 RPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPHGDQQYLFSPSREMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPHGDQQYLFSPSREMP 640 650 660 670 680 690 720 730 740 750 760 770 pF1KA0 TFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSIPPSSRKVETGVKKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSIPPSSRKVETGVKKP 700 710 720 730 740 750 780 790 800 810 820 830 pF1KA0 NIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKEASPPPVQTWIKTPE :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: NP_001 NIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKEASLPPVQTWIKTPE 760 770 780 790 800 810 840 850 860 870 880 890 pF1KA0 IMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVKADSTKYNGPPFPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVKADSTKYNGPPFPPV 820 830 840 850 860 870 900 910 920 930 940 950 pF1KA0 ASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQQIAPSISVSVSETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQQIAPSISVSVSETS 880 890 900 910 920 930 960 970 980 990 1000 1010 pF1KA0 EPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVMLGDREAKKQGPVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVMLGDREAKKQGPVAT 940 950 960 970 980 990 1020 1030 1040 1050 1060 1070 pF1KA0 GVSGDASTNETYLPARVCTPLATPQPTPPCSPSSPAKECVLVKTPDSSPCDSDHDMAFPV ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::: NP_001 GVSGDASTNETYLPARVCTPLPTPQPTPPCSPSSPAKECVLVKTPDSSPCDSDHDMAFPV 1000 1010 1020 1030 1040 1050 1080 1090 1100 1110 1120 1130 pF1KA0 KEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDKLKVSSPELPKPWGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDKLKVSSPELPKPWGD 1060 1070 1080 1090 1100 1110 1140 1150 1160 1170 1180 1190 pF1KA0 GDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEPVPFMPFPAGTKAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEPVPFMPFPAGTKAPS 1120 1130 1140 1150 1160 1170 1200 1210 1220 1230 1240 1250 pF1KA0 PSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPKILEDIGLYLTNLND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPKILEDIGLYLTNLND 1180 1190 1200 1210 1220 1230 1260 1270 1280 1290 1300 1310 pF1KA0 SLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESAVSQQAVYHSEDLEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESAVSQQAVYHSEDLEN 1240 1250 1260 1270 1280 1290 1320 1330 1340 1350 1360 1370 pF1KA0 SVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKPLSRQFDTVSGSIYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKPLSRQFDTVSGSIYE 1300 1310 1320 1330 1340 1350 1380 1390 1400 1410 1420 1430 pF1KA0 DSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFSQYQLKQNQDVKQVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFSQYQLKQNQDVKQVE 1360 1370 1380 1390 1400 1410 1440 1450 1460 1470 1480 1490 pF1KA0 HKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGGKAVPLSASQMPPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGGKAVPLSASQMPPAK 1420 1430 1440 1450 1460 1470 1500 1510 1520 1530 pF1KA0 MSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF :::::::::::::::::::::::::::::::::: NP_001 MSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF 1480 1490 1500 >>NP_001316874 (OMIM: 610178,616490,616546) protein TALP (1441 aa) initn: 9343 init1: 9035 opt: 9035 Z-score: 5337.5 bits: 1000.3 E(85289): 0 Smith-Waterman score: 9303; 98.4% identity (98.4% similar) in 1463 aa overlap (71-1533:1-1441) 50 60 70 80 90 100 pF1KA0 GTGTSLNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKAN :::::::::::::::::::::::::::::: NP_001 MVSESDFSKDVAVQVLPLDKIEENNKQKAN 10 20 30 110 120 130 140 150 160 pF1KA0 DIFISQYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIFISQYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDS 40 50 60 70 80 90 170 180 190 200 210 220 pF1KA0 ATTVAAATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATTVAAATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQ 100 110 120 130 140 150 230 240 250 260 270 280 pF1KA0 EKLHCHDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKLHCHDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEK 160 170 180 190 200 210 290 300 310 320 330 340 pF1KA0 YSVKPEHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSVKPEHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDD 220 230 240 250 260 270 350 360 370 380 390 400 pF1KA0 ELSKRENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELSKRENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEK 280 290 300 310 320 330 410 420 430 440 450 460 pF1KA0 TNRFPSCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNRFPSCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQ 340 350 360 370 380 390 470 480 490 500 510 520 pF1KA0 TTNTTRSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTNTTRSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIR 400 410 420 430 440 450 530 540 550 560 570 580 pF1KA0 IRKTVDEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRKTVDEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSV 460 470 480 490 500 510 590 600 610 620 630 640 pF1KA0 IPRKHSQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPRKHSQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGH 520 530 540 550 560 570 650 660 670 680 690 700 pF1KA0 RSTLKKGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSTLKKGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSV 580 590 600 610 620 630 710 720 730 740 750 760 pF1KA0 PVLPHGDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLPHGDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT 640 650 660 670 680 690 770 780 790 800 810 820 pF1KA0 VTTSIPPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTTSIPPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPL 700 710 720 730 740 750 830 840 850 860 870 880 pF1KA0 SSPKEASPPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEF ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSPKEASLPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEF 760 770 780 790 800 810 890 900 910 920 930 940 pF1KA0 NRSVKADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRSVKADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGL 820 830 840 850 860 870 950 960 970 980 990 1000 pF1KA0 FPVQQQIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPVQQQIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAE 880 890 900 910 920 930 1010 1020 1030 1040 1050 1060 pF1KA0 TIAVMLGDREAKKQGPVATGVSGDASTNETYLPARVCTPLATPQPTPPCSPSSPAKECVL :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 TIAVMLGDREAKKQGPVATGVSGDASTNETYLPARVCTPLPTPQPTPPCSPSSPAKECVL 940 950 960 970 980 990 1070 1080 1090 1100 1110 1120 pF1KA0 VKTPDSSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKTPDSSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSD 1000 1010 1020 1030 1040 1050 1130 1140 1150 1160 1170 1180 pF1KA0 ISIDKLKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISIDKLKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQP 1060 1070 1080 1090 1100 1110 1190 1200 1210 1220 1230 1240 pF1KA0 PPPEPVPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPEPVPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQ 1120 1130 1140 1150 1160 1170 1250 1260 1270 1280 1290 1300 pF1KA0 KLAPKILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLAPKILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQ 1180 1190 1200 1210 1220 1230 1310 1320 1330 1340 1350 1360 pF1KA0 NQESAVSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NQESAVSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQ 1240 1250 1260 1270 1280 1290 1370 1380 1390 1400 1410 1420 pF1KA0 CDPKPLSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CDPKPLSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVA 1300 1310 1320 1330 1340 1350 1430 1440 1450 1460 1470 1480 pF1KA0 AEDFSQYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTC ::::::::::::::::::::::::::::::::::::::::: NP_001 AEDFSQYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQ------------------- 1360 1370 1380 1390 1490 1500 1510 1520 1530 pF1KA0 VFSGGKAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---GGKAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF 1400 1410 1420 1430 1440 >>NP_001231118 (OMIM: 610178,616490,616546) protein TALP (1644 aa) initn: 9648 init1: 8874 opt: 8874 Z-score: 5241.8 bits: 982.7 E(85289): 0 Smith-Waterman score: 9512; 97.1% identity (97.2% similar) in 1516 aa overlap (10-1484:37-1552) 10 20 30 pF1KA0 MPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLP :::::::::::::::::::::::::::::: NP_001 CFVTNNMKGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 VGTGTSLNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGTGTSLNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKA 70 80 90 100 110 120 100 110 120 pF1KA0 NDIFISQYTMGQKDALRTVLKQ-------------------------------------- :::::::::::::::::::::: NP_001 NDIFISQYTMGQKDALRTVLKQNVSLCLTGWSDHSGVITTHCSLYLLRLMRSSHLSLPSS 130 140 150 160 170 180 130 140 150 160 170 pF1KA0 ---KAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVAAATAAAIATAAPL .:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDYRAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVAAATAAAIATAAPL 190 200 210 220 230 240 180 190 200 210 220 230 pF1KA0 IKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHCHDHEKQMNVFMEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHCHDHEKQMNVFMEQ 250 260 270 280 290 300 240 250 260 270 280 290 pF1KA0 HIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKPEHPNLGSCNPSLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKPEHPNLGSCNPSLY 310 320 330 340 350 360 300 310 320 330 340 350 pF1KA0 NTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKRENLLEEKENMEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKRENLLEEKENMEVS 370 380 390 400 410 420 360 370 380 390 400 410 pF1KA0 CHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFPSCEELETTKVTMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFPSCEELETTKVTMQ 430 440 450 460 470 480 420 430 440 450 460 470 pF1KA0 KSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTTRSVLKDAEKILRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTTRSVLKDAEKILRG 490 500 510 520 530 540 480 490 500 510 520 530 pF1KA0 VQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQD 550 560 570 580 590 600 540 550 560 570 580 590 pF1KA0 ELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKHSQKQIEEHFRNLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKHSQKQIEEHFRNLP 610 620 630 640 650 660 600 610 620 630 640 650 pF1KA0 MRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLKKGPYLRFNSPSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLKKGPYLRFNSPSPK 670 680 690 700 710 720 660 670 680 690 700 710 pF1KA0 SRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPHGDQQYLFSPSREM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPHGDQQYLFSPSREM 730 740 750 760 770 780 720 730 740 750 760 770 pF1KA0 PTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSIPPSSRKVETGVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSIPPSSRKVETGVKK 790 800 810 820 830 840 780 790 800 810 820 830 pF1KA0 PNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKEASPPPVQTWIKTP ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_001 PNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKEASLPPVQTWIKTP 850 860 870 880 890 900 840 850 860 870 880 890 pF1KA0 EIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVKADSTKYNGPPFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVKADSTKYNGPPFPP 910 920 930 940 950 960 900 910 920 930 940 950 pF1KA0 VASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQQIAPSISVSVSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQQIAPSISVSVSET 970 980 990 1000 1010 1020 960 970 980 990 1000 1010 pF1KA0 SEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVMLGDREAKKQGPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVMLGDREAKKQGPVA 1030 1040 1050 1060 1070 1080 1020 1030 1040 1050 1060 1070 pF1KA0 TGVSGDASTNETYLPARVCTPLATPQPTPPCSPSSPAKECVLVKTPDSSPCDSDHDMAFP :::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::: NP_001 TGVSGDASTNETYLPARVCTPLPTPQPTPPCSPSSPAKECVLVKTPDSSPCDSDHDMAFP 1090 1100 1110 1120 1130 1140 1080 1090 1100 1110 1120 1130 pF1KA0 VKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDKLKVSSPELPKPWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDKLKVSSPELPKPWG 1150 1160 1170 1180 1190 1200 1140 1150 1160 1170 1180 1190 pF1KA0 DGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEPVPFMPFPAGTKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEPVPFMPFPAGTKAP 1210 1220 1230 1240 1250 1260 1200 1210 1220 1230 1240 1250 pF1KA0 SPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPKILEDIGLYLTNLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPKILEDIGLYLTNLN 1270 1280 1290 1300 1310 1320 1260 1270 1280 1290 1300 1310 pF1KA0 DSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESAVSQQAVYHSEDLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESAVSQQAVYHSEDLE 1330 1340 1350 1360 1370 1380 1320 1330 1340 1350 1360 1370 pF1KA0 NSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKPLSRQFDTVSGSIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKPLSRQFDTVSGSIY 1390 1400 1410 1420 1430 1440 1380 1390 1400 1410 1420 1430 pF1KA0 EDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFSQYQLKQNQDVKQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFSQYQLKQNQDVKQV 1450 1460 1470 1480 1490 1500 1440 1450 1460 1470 1480 1490 pF1KA0 EHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGGKAVPLSASQMPPA :::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGLGVHVKKVSCIGKL 1510 1520 1530 1540 1550 1560 1500 1510 1520 1530 pF1KA0 KMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF NP_001 GLWRFVIQIISSPRWESSATLRFTDAPCQDVSDAAVSEPRGLLSVSESQHNAGGHGVFGG 1570 1580 1590 1600 1610 1620 >>NP_001231122 (OMIM: 610178,616490,616546) protein TALP (1347 aa) initn: 8699 init1: 8699 opt: 8699 Z-score: 5139.9 bits: 963.6 E(85289): 0 Smith-Waterman score: 8699; 99.9% identity (99.9% similar) in 1337 aa overlap (126-1462:1-1337) 100 110 120 130 140 150 pF1KA0 KQKANDIFISQYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISP :::::::::::::::::::::::::::::: NP_001 MPVFKEVKVHLLEDAGIEKDAVTQETRISP 10 20 30 160 170 180 190 200 210 pF1KA0 SGIDSATTVAAATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGIDSATTVAAATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTS 40 50 60 70 80 90 220 230 240 250 260 270 pF1KA0 IQRKQEKLHCHDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQRKQEKLHCHDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSS 100 110 120 130 140 150 280 290 300 310 320 330 pF1KA0 RAVEKYSVKPEHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAVEKYSVKPEHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVP 160 170 180 190 200 210 340 350 360 370 380 390 pF1KA0 VSRDDELSKRENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSRDDELSKRENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIG 220 230 240 250 260 270 400 410 420 430 440 450 pF1KA0 WTPEKTNRFPSCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WTPEKTNRFPSCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQN 280 290 300 310 320 330 460 470 480 490 500 510 pF1KA0 SVKLQTTNTTRSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVKLQTTNTTRSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREM 340 350 360 370 380 390 520 530 540 550 560 570 pF1KA0 SEKIRIRKTVDEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEKIRIRKTVDEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKT 400 410 420 430 440 450 580 590 600 610 620 630 pF1KA0 VNKSVIPRKHSQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNKSVIPRKHSQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKP 460 470 480 490 500 510 640 650 660 670 680 690 pF1KA0 VYQGHRSTLKKGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYQGHRSTLKKGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSK 520 530 540 550 560 570 700 710 720 730 740 750 pF1KA0 MKHSVPVLPHGDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKHSVPVLPHGDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSK 580 590 600 610 620 630 760 770 780 790 800 810 pF1KA0 PHPVTVTTSIPPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHPVTVTTSIPPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSAD 640 650 660 670 680 690 820 830 840 850 860 870 pF1KA0 VLSPLSSPKEASPPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSE :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLSPLSSPKEASLPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSE 700 710 720 730 740 750 880 890 900 910 920 930 pF1KA0 PILEFNRSVKADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PILEFNRSVKADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSR 760 770 780 790 800 810 940 950 960 970 980 990 pF1KA0 IISGLFPVQQQIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IISGLFPVQQQIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVN 820 830 840 850 860 870 1000 1010 1020 1030 1040 1050 pF1KA0 EALAETIAVMLGDREAKKQGPVATGVSGDASTNETYLPARVCTPLATPQPTPPCSPSSPA ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: NP_001 EALAETIAVMLGDREAKKQGPVATGVSGDASTNETYLPARVCTPLPTPQPTPPCSPSSPA 880 890 900 910 920 930 1060 1070 1080 1090 1100 1110 pF1KA0 KECVLVKTPDSSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KECVLVKTPDSSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFT 940 950 960 970 980 990 1120 1130 1140 1150 1160 1170 pF1KA0 PTLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMD 1000 1010 1020 1030 1040 1050 1180 1190 1200 1210 1220 1230 pF1KA0 FPAQPPPPEPVPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPAQPPPPEPVPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEIL 1060 1070 1080 1090 1100 1110 1240 1250 1260 1270 1280 1290 pF1KA0 FSCGQKLAPKILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSCGQKLAPKILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAIL 1120 1130 1140 1150 1160 1170 1300 1310 1320 1330 1340 1350 pF1KA0 SFAKQNQESAVSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFAKQNQESAVSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQ 1180 1190 1200 1210 1220 1230 1360 1370 1380 1390 1400 1410 pF1KA0 SLDQQCDPKPLSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLDQQCDPKPLSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDV 1240 1250 1260 1270 1280 1290 1420 1430 1440 1450 1460 1470 pF1KA0 NLPVAAEDFSQYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELN ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLPVAAEDFSQYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVLISRIKNCKN 1300 1310 1320 1330 1340 1480 1490 1500 1510 1520 1530 pF1KA0 PYLTCVFSGGKAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF >>NP_001316876 (OMIM: 610178,616490,616546) protein TALP (1504 aa) initn: 8299 init1: 8258 opt: 8261 Z-score: 4881.0 bits: 915.9 E(85289): 0 Smith-Waterman score: 9592; 97.0% identity (97.0% similar) in 1533 aa overlap (1-1533:16-1504) 10 20 30 40 pF1KA0 MPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTS ::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 LNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNGTSRGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFIS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 QYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYTMGQKDALRTVLKQKAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVA 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 AATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRKQEKLHC 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 HDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKYSVKP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 EHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHPNLGSCNPSLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKR 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 ENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENLLEEKENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFP 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 SCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCEELETTKVTMQKSDDVLHDLGQKEKETNSMVQPKESLSMLKLPDLPQNSVKLQTTNTT 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 RSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSVLKDAEKILRGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTV 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 DEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEWIKTISAEIQDELSRTDYEQKRFDQKNQRTKKGQNMTKDIRTNTQDKTVNKSVIPRKH 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 SQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQKQIEEHFRNLPMRGMPASSLQKERKEGLLKATTVIQDEDYMLQVYGKPVYQGHRSTLK 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 KGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVLPH 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 GDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDQQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSI 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 PPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVLSPLSSPKE 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 ASPPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVK :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASLPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEEKCDEIPDSEPILEFNRSVK 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 ADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQ 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 QIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVM 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA0 LGDREAKKQGPVATGVSGDASTNETYLPARVCTPLATPQPTPPCSPSSPAKECVLVKTPD ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: NP_001 LGDREAKKQGPVATGVSGDASTNETYLPARVCTPLPTPQPTPPCSPSSPAKECVLVKTPD 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA0 SSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSPCDSDHDMAFPVKEICAEKGDDMPAIMLVNTPTVTPTTTPPPAAAVFTPTLSDISIDK 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA0 LKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDFPAQPPPPEP 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA0 VPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPK 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA0 ILEDIGLYLTNLNDSLSSTLHDAVEMEDDPPSEGQVIRMSHKKFHADAILSFAKQNQESA :::::::::::::::::::::::::: NP_001 ILEDIGLYLTNLNDSLSSTLHDAVEM---------------------------------- 1270 1280 1310 1320 1330 1340 1350 1360 pF1KA0 VSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKP :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ----------DLENSVGELSEGQRPQLTAAAENILMGHSLYMQPPVTNTQSLDQQCDPKP 1290 1300 1310 1320 1330 1370 1380 1390 1400 1410 1420 pF1KA0 LSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSRQFDTVSGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLTAQENDVNLPVAAEDFS 1340 1350 1360 1370 1380 1390 1430 1440 1450 1460 1470 1480 pF1KA0 QYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYQLKQNQDVKQVEHKPSQSYLRVRNKSDIAPSQQQVSPGDMDRTQIELNPYLTCVFSGG 1400 1410 1420 1430 1440 1450 1490 1500 1510 1520 1530 pF1KA0 KAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAVPLSASQMPPAKMSVMLPSVNLEDCSQSLSLSTMQEDMESSGADTF 1460 1470 1480 1490 1500 1533 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:47:39 2016 done: Fri Nov 4 00:47:42 2016 Total Scan time: 16.480 Total Display time: 0.850 Function used was FASTA [36.3.4 Apr, 2011]