FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0589, 668 aa 1>>>pF1KA0589 668 - 668 aa - 668 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3244+/-0.000391; mu= 5.3712+/- 0.024 mean_var=161.0578+/-32.697, 0's: 0 Z-trim(117.4): 72 B-trim: 295 in 1/57 Lambda= 0.101061 statistics sampled from 29370 (29452) to 29370 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.345), width: 16 Scan time: 10.120 The best scores are: opt bits E(85289) NP_036530 (OMIM: 606102,611369) phosphatidylinosit ( 668) 4383 651.5 2.9e-186 XP_011526150 (OMIM: 606102,611369) PREDICTED: phos ( 672) 4246 631.5 3e-180 NP_001287778 (OMIM: 606102,611369) phosphatidylino ( 707) 4246 631.5 3.1e-180 NP_001182662 (OMIM: 606102,611369) phosphatidylino ( 640) 4184 622.5 1.5e-177 XP_011526151 (OMIM: 606102,611369) PREDICTED: phos ( 646) 4184 622.5 1.5e-177 XP_011526147 (OMIM: 606102,611369) PREDICTED: phos ( 731) 4184 622.5 1.7e-177 XP_011526152 (OMIM: 606102,611369) PREDICTED: phos ( 686) 3908 582.2 2.1e-165 XP_016882029 (OMIM: 606102,611369) PREDICTED: phos ( 657) 3684 549.6 1.4e-155 XP_011526148 (OMIM: 606102,611369) PREDICTED: phos ( 720) 3684 549.6 1.5e-155 NP_001129110 (OMIM: 603275) phosphatidylinositol 4 ( 562) 2285 345.6 3e-94 NP_001317618 (OMIM: 603275) phosphatidylinositol 4 ( 550) 2280 344.8 4.9e-94 XP_005245585 (OMIM: 603275) PREDICTED: phosphatidy ( 560) 2276 344.3 7.4e-94 XP_005245589 (OMIM: 603275) PREDICTED: phosphatidy ( 542) 2275 344.1 8e-94 XP_011508345 (OMIM: 603275) PREDICTED: phosphatidy ( 555) 2275 344.1 8.2e-94 XP_005245584 (OMIM: 603275) PREDICTED: phosphatidy ( 561) 2275 344.1 8.3e-94 XP_006711627 (OMIM: 603275) PREDICTED: phosphatidy ( 562) 2272 343.7 1.1e-93 NP_003548 (OMIM: 603275) phosphatidylinositol 4-ph ( 549) 2271 343.5 1.2e-93 XP_011508348 (OMIM: 603275) PREDICTED: phosphatidy ( 541) 2270 343.4 1.3e-93 XP_005245582 (OMIM: 603275) PREDICTED: phosphatidy ( 572) 2269 343.2 1.5e-93 XP_005245587 (OMIM: 603275) PREDICTED: phosphatidy ( 554) 2268 343.1 1.7e-93 XP_006711631 (OMIM: 603275) PREDICTED: phosphatidy ( 567) 2268 343.1 1.7e-93 XP_016857930 (OMIM: 603275) PREDICTED: phosphatidy ( 526) 2266 342.8 1.9e-93 XP_011508351 (OMIM: 603275) PREDICTED: phosphatidy ( 526) 2266 342.8 1.9e-93 XP_011508350 (OMIM: 603275) PREDICTED: phosphatidy ( 526) 2266 342.8 1.9e-93 XP_006711630 (OMIM: 603275) PREDICTED: phosphatidy ( 526) 2266 342.8 1.9e-93 XP_011508347 (OMIM: 603275) PREDICTED: phosphatidy ( 553) 2266 342.8 2e-93 XP_006711626 (OMIM: 603275) PREDICTED: phosphatidy ( 574) 2266 342.8 2.1e-93 XP_016857928 (OMIM: 603275) PREDICTED: phosphatidy ( 485) 2183 330.7 8e-90 NP_001129109 (OMIM: 603275) phosphatidylinositol 4 ( 500) 2177 329.8 1.5e-89 XP_016857929 (OMIM: 603275) PREDICTED: phosphatidy ( 484) 2174 329.4 2e-89 NP_001265182 (OMIM: 602745) phosphatidylinositol 4 ( 502) 2166 328.2 4.6e-89 XP_016870680 (OMIM: 602745) PREDICTED: phosphatidy ( 502) 2166 328.2 4.6e-89 XP_006717364 (OMIM: 602745) PREDICTED: phosphatidy ( 502) 2166 328.2 4.6e-89 XP_006717363 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 2166 328.2 4.9e-89 XP_016870679 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 2166 328.2 4.9e-89 XP_005252319 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 2166 328.2 4.9e-89 XP_016870678 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 2166 328.2 4.9e-89 XP_005252318 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 2166 328.2 4.9e-89 XP_011517386 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 2166 328.2 4.9e-89 NP_003549 (OMIM: 602745) phosphatidylinositol 4-ph ( 540) 2166 328.2 4.9e-89 XP_011517385 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 2166 328.2 4.9e-89 XP_016870677 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 2166 328.2 4.9e-89 XP_011517384 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 2166 328.2 4.9e-89 NP_001129108 (OMIM: 603275) phosphatidylinositol 4 ( 522) 1776 271.3 6.2e-72 XP_011526155 (OMIM: 606102,611369) PREDICTED: phos ( 355) 1717 262.7 1.7e-69 XP_011526153 (OMIM: 606102,611369) PREDICTED: phos ( 399) 1717 262.7 1.9e-69 NP_005019 (OMIM: 603140) phosphatidylinositol 5-ph ( 406) 554 93.1 2.2e-18 NP_001316991 (OMIM: 603140) phosphatidylinositol 5 ( 347) 539 90.9 8.6e-18 XP_016871819 (OMIM: 603140) PREDICTED: phosphatidy ( 347) 539 90.9 8.6e-18 XP_016871820 (OMIM: 603140) PREDICTED: phosphatidy ( 347) 539 90.9 8.6e-18 >>NP_036530 (OMIM: 606102,611369) phosphatidylinositol 4 (668 aa) initn: 4383 init1: 4383 opt: 4383 Z-score: 3465.1 bits: 651.5 E(85289): 2.9e-186 Smith-Waterman score: 4383; 100.0% identity (100.0% similar) in 668 aa overlap (1-668:1-668) 10 20 30 40 50 60 pF1KA0 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP 610 620 630 640 650 660 pF1KA0 ASDGESDT :::::::: NP_036 ASDGESDT >>XP_011526150 (OMIM: 606102,611369) PREDICTED: phosphat (672 aa) initn: 4310 init1: 4246 opt: 4246 Z-score: 3357.1 bits: 631.5 E(85289): 3e-180 Smith-Waterman score: 4246; 98.6% identity (98.9% similar) in 658 aa overlap (1-658:1-658) 10 20 30 40 50 60 pF1KA0 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP :::::::::::::::::::::::::::::::::::::::: :: : :.::: : .: XP_011 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFFTDGRYWIYSPRHRRLRAVT 610 620 630 640 650 660 pF1KA0 ASDGESDT XP_011 LSASGTALPRLN 670 >>NP_001287778 (OMIM: 606102,611369) phosphatidylinosito (707 aa) initn: 4310 init1: 4246 opt: 4246 Z-score: 3356.7 bits: 631.5 E(85289): 3.1e-180 Smith-Waterman score: 4246; 98.6% identity (98.9% similar) in 658 aa overlap (1-658:1-658) 10 20 30 40 50 60 pF1KA0 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP :::::::::::::::::::::::::::::::::::::::: :: : :.::: : .: NP_001 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFFTDGRYWIYSPRHRRLRAVT 610 620 630 640 650 660 pF1KA0 ASDGESDT NP_001 LSASGTVSDRSRPPWGEGAVPLGQQGAAGPRPEAQCLTSVVFQKGFG 670 680 690 700 >>NP_001182662 (OMIM: 606102,611369) phosphatidylinosito (640 aa) initn: 4184 init1: 4184 opt: 4184 Z-score: 3308.5 bits: 622.5 E(85289): 1.5e-177 Smith-Waterman score: 4184; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KA0 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP :::::::::::::::::::::::::::::::::::::::: NP_001 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYF 610 620 630 640 pF1KA0 ASDGESDT >>XP_011526151 (OMIM: 606102,611369) PREDICTED: phosphat (646 aa) initn: 4184 init1: 4184 opt: 4184 Z-score: 3308.5 bits: 622.5 E(85289): 1.5e-177 Smith-Waterman score: 4184; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KA0 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP :::::::::::::::::::::::::::::::::::::::: XP_011 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFALPRLN 610 620 630 640 pF1KA0 ASDGESDT >>XP_011526147 (OMIM: 606102,611369) PREDICTED: phosphat (731 aa) initn: 4184 init1: 4184 opt: 4184 Z-score: 3307.7 bits: 622.5 E(85289): 1.7e-177 Smith-Waterman score: 4184; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KA0 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP :::::::::::::::::::::::::::::::::::::::: XP_011 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFWRLWGPHAPTWPWRREGRAA 610 620 630 640 650 660 pF1KA0 ASDGESDT XP_011 CLCPYPPHVVTPFPGTGLCASWSPDVHGWEVLDLLSPPSPTAGRDAERLGDCPASTELTA 670 680 690 700 710 720 >>XP_011526152 (OMIM: 606102,611369) PREDICTED: phosphat (686 aa) initn: 3908 init1: 3908 opt: 3908 Z-score: 3090.6 bits: 582.2 E(85289): 2.1e-165 Smith-Waterman score: 3908; 100.0% identity (100.0% similar) in 595 aa overlap (46-640:1-595) 20 30 40 50 60 70 pF1KA0 AVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGHRGVDASGETTYKKTT :::::::::::::::::::::::::::::: XP_011 MTAQPGPGHGKKLGHRGVDASGETTYKKTT 10 20 30 80 90 100 110 120 130 pF1KA0 SSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKT 40 50 60 70 80 90 140 150 160 170 180 190 pF1KA0 YAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEA 100 110 120 130 140 150 200 210 220 230 240 250 pF1KA0 EFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLK 160 170 180 190 200 210 260 270 280 290 300 310 pF1KA0 GSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIM 220 230 240 250 260 270 320 330 340 350 360 370 pF1KA0 DYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMESIQGGAARGEAIESDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMESIQGGAARGEAIESDD 280 290 300 310 320 330 380 390 400 410 420 430 pF1KA0 TMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERF 340 350 360 370 380 390 440 450 460 470 480 490 pF1KA0 FKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQIPSEREEAQYDLRGAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQIPSEREEAQYDLRGAR 400 410 420 430 440 450 500 510 520 530 540 550 pF1KA0 SYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSPSETSEQPRYRRRTQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSPSETSEQPRYRRRTQS 460 470 480 490 500 510 560 570 580 590 600 610 pF1KA0 SGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEASPAGASAAVEVETASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEASPAGASAAVEVETASQ 520 530 540 550 560 570 620 630 640 650 660 pF1KA0 ASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPPASDGESDT ::::::::::::::::::::::::: XP_011 ASDEEGAPASQASDEEDAPATDIYFWRLWGPHAPTWPWRREGRAACLCPYPPHVVTPFPG 580 590 600 610 620 630 >>XP_016882029 (OMIM: 606102,611369) PREDICTED: phosphat (657 aa) initn: 3663 init1: 3663 opt: 3684 Z-score: 2914.4 bits: 549.6 E(85289): 1.4e-155 Smith-Waterman score: 4277; 98.4% identity (98.4% similar) in 668 aa overlap (1-668:1-657) 10 20 30 40 50 60 pF1KA0 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS :::::::::: ::::::::::::::::::::::::::::::::::::::: XP_016 SETSEQPRYR-----------PQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS 550 560 570 580 610 620 630 640 650 660 pF1KA0 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP 590 600 610 620 630 640 pF1KA0 ASDGESDT :::::::: XP_016 ASDGESDT 650 >>XP_011526148 (OMIM: 606102,611369) PREDICTED: phosphat (720 aa) initn: 3663 init1: 3663 opt: 3684 Z-score: 2913.8 bits: 549.6 E(85289): 1.5e-155 Smith-Waterman score: 4078; 98.3% identity (98.3% similar) in 640 aa overlap (1-640:1-629) 10 20 30 40 50 60 pF1KA0 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS ::::::::: :::::::::::::::::::::::::::::::::::::::: XP_011 SETSEQPRY-----------RPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS 550 560 570 580 610 620 630 640 650 660 pF1KA0 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP :::::::::::::::::::::::::::::::::::::::: XP_011 PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFWRLWGPHAPTWPWRREGRAA 590 600 610 620 630 640 pF1KA0 ASDGESDT XP_011 CLCPYPPHVVTPFPGTGLCASWSPDVHGWEVLDLLSPPSPTAGRDAERLGDCPASTELTA 650 660 670 680 690 700 >>NP_001129110 (OMIM: 603275) phosphatidylinositol 4-pho (562 aa) initn: 2266 init1: 2169 opt: 2285 Z-score: 1813.0 bits: 345.6 E(85289): 3e-94 Smith-Waterman score: 2285; 69.7% identity (84.6% similar) in 512 aa overlap (16-523:20-526) 10 20 30 40 50 pF1KA0 MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQK--KAAPTEVLSMTAQPGPGH :::: . .: :: .:.. .: .:.. . NP_001 MASASSGPSSSVGFSSFDPAVPSCTLSSAASGIKRPMASEVLEARQDSYISLVPYASGMP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 GKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIF ::.:::.::.::::::::::::.::::::::: .::: ::.:::::::::::::::::: NP_001 IKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 FPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASG :::::::::::::..:::::::::::::::::::::::::::::::.:::::: . :::: NP_001 FPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 SLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIR :::::.::::::::::.::::::::::::::::::::::::::::::::::::.:::::: NP_001 SLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 VVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADT .:::::.::: ::::.:.::::::::::::.::.:: .::.:::::.::.:.::.:::: NP_001 IVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADM 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 FSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALY ..:: ::::::::::.::::::::::...::::. .:: .. .: . : .::. ::::: NP_001 YNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALY 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 STAMESIQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWK ::::::::: : :: ..:.:: :::::: :..::::::.::::::::::::.:::::.:: NP_001 STAMESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 ALVHDGDTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAA ::::::::::::::.:::::: .:: ::::.: :: ::::: :.:. .. . : .. NP_001 ALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIP-LKPSPSKKFRSGSSFSRRA-GSSGN 430 440 450 460 470 480 490 500 510 520 530 pF1KA0 FSASQIPSEREE--AQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTS . :: : :: . :. : .. ::::.:: ::: .:: . .: NP_001 SCITYQPSVSGEHKAQVTTK-AEVEPGVH-LGRPDVLPQTPP-LEEISEGSPIPDPSFSP 480 490 500 510 520 530 540 550 560 570 580 590 pF1KA0 LSIPERSPSETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKE NP_001 LVGETLQMLTTSTTLEKLEVAESEFTH 540 550 560 668 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:21:55 2016 done: Wed Nov 2 19:21:57 2016 Total Scan time: 10.120 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]