FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0594, 1101 aa 1>>>pF1KA0594 1101 - 1101 aa - 1101 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8626+/-0.000645; mu= -3.9390+/- 0.040 mean_var=368.5288+/-77.120, 0's: 0 Z-trim(115.2): 204 B-trim: 139 in 1/52 Lambda= 0.066810 statistics sampled from 25379 (25583) to 25379 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.3), width: 16 Scan time: 15.650 The best scores are: opt bits E(85289) NP_055925 (OMIM: 609386) structural maintenance of (1101) 7172 707.1 1.4e-202 XP_016869996 (OMIM: 609386) PREDICTED: structural (1068) 6857 676.7 1.9e-193 XP_005251894 (OMIM: 609386) PREDICTED: structural (1086) 5466 542.7 4.5e-153 XP_016869997 (OMIM: 609386) PREDICTED: structural ( 880) 5442 540.3 1.9e-152 XP_005251895 (OMIM: 609386) PREDICTED: structural (1077) 4881 486.3 4.2e-136 XP_016869998 (OMIM: 609386) PREDICTED: structural ( 723) 4692 467.9 9.5e-131 XP_005251896 (OMIM: 609386) PREDICTED: structural (1063) 3777 379.9 4.5e-104 XP_016869999 (OMIM: 609386) PREDICTED: structural ( 685) 3720 374.2 1.5e-102 XP_011531410 (OMIM: 609387) PREDICTED: structural (1083) 503 64.3 4.5e-09 XP_016860403 (OMIM: 609387) PREDICTED: structural (1110) 414 55.7 1.7e-06 XP_016860402 (OMIM: 609387) PREDICTED: structural (1110) 414 55.7 1.7e-06 XP_011531409 (OMIM: 609387) PREDICTED: structural (1110) 414 55.7 1.7e-06 NP_078900 (OMIM: 609387) structural maintenance of (1091) 323 47.0 0.00075 NP_001135758 (OMIM: 609387) structural maintenance (1091) 323 47.0 0.00075 XP_016860404 (OMIM: 609387) PREDICTED: structural (1091) 323 47.0 0.00075 >>NP_055925 (OMIM: 609386) structural maintenance of chr (1101 aa) initn: 7172 init1: 7172 opt: 7172 Z-score: 3757.8 bits: 707.1 E(85289): 1.4e-202 Smith-Waterman score: 7172; 99.9% identity (100.0% similar) in 1101 aa overlap (1-1101:1-1101) 10 20 30 40 50 60 pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EGQIPVTCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP 1030 1040 1050 1060 1070 1080 1090 1100 pF1KA0 NTWNLKAFQRRRRRITFTQPS ::::::::::::::::::::: NP_055 NTWNLKAFQRRRRRITFTQPS 1090 1100 >>XP_016869996 (OMIM: 609386) PREDICTED: structural main (1068 aa) initn: 6857 init1: 6857 opt: 6857 Z-score: 3593.9 bits: 676.7 E(85289): 1.9e-193 Smith-Waterman score: 6857; 99.9% identity (100.0% similar) in 1055 aa overlap (1-1055:1-1055) 10 20 30 40 50 60 pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGQIPVTCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP ::::::::::::::::::::::::::::::::::: XP_016 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKDTRLSKKLLEKCL 1030 1040 1050 1060 1090 1100 pF1KA0 NTWNLKAFQRRRRRITFTQPS >>XP_005251894 (OMIM: 609386) PREDICTED: structural main (1086 aa) initn: 5455 init1: 5455 opt: 5466 Z-score: 2869.2 bits: 542.7 E(85289): 4.5e-153 Smith-Waterman score: 7026; 98.5% identity (98.6% similar) in 1101 aa overlap (1-1101:1-1086) 10 20 30 40 50 60 pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGQIPVTCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI : :::::::::::::::::::::::::::::::::::::::::::: XP_005 T---------------VFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI 850 860 870 880 910 920 930 940 950 960 pF1KA0 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KA0 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KA0 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP 1010 1020 1030 1040 1050 1060 1090 1100 pF1KA0 NTWNLKAFQRRRRRITFTQPS ::::::::::::::::::::: XP_005 NTWNLKAFQRRRRRITFTQPS 1070 1080 >>XP_016869997 (OMIM: 609386) PREDICTED: structural main (880 aa) initn: 5442 init1: 5442 opt: 5442 Z-score: 2857.9 bits: 540.3 E(85289): 1.9e-152 Smith-Waterman score: 5442; 99.9% identity (100.0% similar) in 841 aa overlap (1-841:1-841) 10 20 30 40 50 60 pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGQIPVTCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI : XP_016 TILDPFYQFSKYPPFQMDTTPHSPWFSKTFQTHWMKLMLY 850 860 870 880 >>XP_005251895 (OMIM: 609386) PREDICTED: structural main (1077 aa) initn: 4863 init1: 4863 opt: 4881 Z-score: 2564.5 bits: 486.3 E(85289): 4.2e-136 Smith-Waterman score: 6956; 97.7% identity (97.8% similar) in 1101 aa overlap (1-1101:1-1077) 10 20 30 40 50 60 pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI :::::.::::::::::::::::::::: ::::::::: XP_005 EGQIPVTCRIEEMENERHNLEARIKEK------------------------IEELQQALI 310 320 330 370 380 390 400 410 420 pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE 340 350 360 370 380 390 430 440 450 460 470 480 pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR 400 410 420 430 440 450 490 500 510 520 530 540 pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA 460 470 480 490 500 510 550 560 570 580 590 600 pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI 520 530 540 550 560 570 610 620 630 640 650 660 pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK 580 590 600 610 620 630 670 680 690 700 710 720 pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL 640 650 660 670 680 690 730 740 750 760 770 780 pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE 700 710 720 730 740 750 790 800 810 820 830 840 pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ 760 770 780 790 800 810 850 860 870 880 890 900 pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI 820 830 840 850 860 870 910 920 930 940 950 960 pF1KA0 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KA0 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KA0 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP 1000 1010 1020 1030 1040 1050 1090 1100 pF1KA0 NTWNLKAFQRRRRRITFTQPS ::::::::::::::::::::: XP_005 NTWNLKAFQRRRRRITFTQPS 1060 1070 >>XP_016869998 (OMIM: 609386) PREDICTED: structural main (723 aa) initn: 4692 init1: 4692 opt: 4692 Z-score: 2468.3 bits: 467.9 E(85289): 9.5e-131 Smith-Waterman score: 4692; 100.0% identity (100.0% similar) in 723 aa overlap (379-1101:1-723) 350 360 370 380 390 400 pF1KA0 DKHIEELQQALIVKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLR :::::::::::::::::::::::::::::: XP_016 MIEDLQNELKTTENCENLQPQIDAITNDLR 10 20 30 410 420 430 440 450 460 pF1KA0 RIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVL 40 50 60 70 80 90 470 480 490 500 510 520 pF1KA0 WLRNNRDKFKQRVCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WLRNNRDKFKQRVCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVR 100 110 120 130 140 150 530 540 550 560 570 580 pF1KA0 DNKKLRVNAVIAPKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNKKLRVNAVIAPKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHE 160 170 180 190 200 210 590 600 610 620 630 640 pF1KA0 VPVGTEKTRERIERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPVGTEKTRERIERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVD 220 230 240 250 260 270 650 660 670 680 690 700 pF1KA0 LEQRRHLEEQLKEIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEQRRHLEEQLKEIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLE 280 290 300 310 320 330 710 720 730 740 750 760 pF1KA0 QKISSKLGSLKLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKISSKLGSLKLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKV 340 350 360 370 380 390 770 780 790 800 810 820 pF1KA0 DLILQNTTVISEKNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLILQNTTVISEKNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCN 400 410 420 430 440 450 830 840 850 860 870 880 pF1KA0 LGAEQTLPQEYQTQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGAEQTLPQEYQTQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPT 460 470 480 490 500 510 890 900 910 920 930 940 pF1KA0 IVQEYTKREEEIEQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVQEYTKREEEIEQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFS 520 530 540 550 560 570 950 960 970 980 990 1000 pF1KA0 SMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQ 580 590 600 610 620 630 1010 1020 1030 1040 1050 1060 pF1KA0 ELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTV 640 650 660 670 680 690 1070 1080 1090 1100 pF1KA0 LFVYNGPHMLEPNTWNLKAFQRRRRRITFTQPS ::::::::::::::::::::::::::::::::: XP_016 LFVYNGPHMLEPNTWNLKAFQRRRRRITFTQPS 700 710 720 >>XP_005251896 (OMIM: 609386) PREDICTED: structural main (1063 aa) initn: 3713 init1: 3713 opt: 3777 Z-score: 1989.5 bits: 379.9 E(85289): 4.5e-104 Smith-Waterman score: 6838; 96.5% identity (96.5% similar) in 1101 aa overlap (1-1101:1-1063) 10 20 30 40 50 60 pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGQIPVTCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA :::::::: :::::::::::::: XP_005 VCEPIMLT--------------------------------------VRDNKKLRVNAVIA 490 500 550 560 570 580 590 600 pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI 510 520 530 540 550 560 610 620 630 640 650 660 pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK 570 580 590 600 610 620 670 680 690 700 710 720 pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL 630 640 650 660 670 680 730 740 750 760 770 780 pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE 690 700 710 720 730 740 790 800 810 820 830 840 pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ 750 760 770 780 790 800 850 860 870 880 890 900 pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI 810 820 830 840 850 860 910 920 930 940 950 960 pF1KA0 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT 870 880 890 900 910 920 970 980 990 1000 1010 1020 pF1KA0 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE 930 940 950 960 970 980 1030 1040 1050 1060 1070 1080 pF1KA0 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP 990 1000 1010 1020 1030 1040 1090 1100 pF1KA0 NTWNLKAFQRRRRRITFTQPS ::::::::::::::::::::: XP_005 NTWNLKAFQRRRRRITFTQPS 1050 1060 >>XP_016869999 (OMIM: 609386) PREDICTED: structural main (685 aa) initn: 3713 init1: 3713 opt: 3720 Z-score: 1962.3 bits: 374.2 E(85289): 1.5e-102 Smith-Waterman score: 4358; 94.7% identity (94.7% similar) in 723 aa overlap (379-1101:1-685) 350 360 370 380 390 400 pF1KA0 DKHIEELQQALIVKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLR :::::::::::::::::::::::::::::: XP_016 MIEDLQNELKTTENCENLQPQIDAITNDLR 10 20 30 410 420 430 440 450 460 pF1KA0 RIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVL 40 50 60 70 80 90 470 480 490 500 510 520 pF1KA0 WLRNNRDKFKQRVCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVR :::::::::::::::::::: :: XP_016 WLRNNRDKFKQRVCEPIMLT--------------------------------------VR 100 110 530 540 550 560 570 580 pF1KA0 DNKKLRVNAVIAPKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNKKLRVNAVIAPKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHE 120 130 140 150 160 170 590 600 610 620 630 640 pF1KA0 VPVGTEKTRERIERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPVGTEKTRERIERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVD 180 190 200 210 220 230 650 660 670 680 690 700 pF1KA0 LEQRRHLEEQLKEIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEQRRHLEEQLKEIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLE 240 250 260 270 280 290 710 720 730 740 750 760 pF1KA0 QKISSKLGSLKLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKISSKLGSLKLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKV 300 310 320 330 340 350 770 780 790 800 810 820 pF1KA0 DLILQNTTVISEKNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLILQNTTVISEKNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCN 360 370 380 390 400 410 830 840 850 860 870 880 pF1KA0 LGAEQTLPQEYQTQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGAEQTLPQEYQTQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPT 420 430 440 450 460 470 890 900 910 920 930 940 pF1KA0 IVQEYTKREEEIEQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVQEYTKREEEIEQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFS 480 490 500 510 520 530 950 960 970 980 990 1000 pF1KA0 SMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQ 540 550 560 570 580 590 1010 1020 1030 1040 1050 1060 pF1KA0 ELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTV 600 610 620 630 640 650 1070 1080 1090 1100 pF1KA0 LFVYNGPHMLEPNTWNLKAFQRRRRRITFTQPS ::::::::::::::::::::::::::::::::: XP_016 LFVYNGPHMLEPNTWNLKAFQRRRRRITFTQPS 660 670 680 >>XP_011531410 (OMIM: 609387) PREDICTED: structural main (1083 aa) initn: 346 init1: 187 opt: 503 Z-score: 283.9 bits: 64.3 E(85289): 4.5e-09 Smith-Waterman score: 555; 21.2% identity (54.7% similar) in 1133 aa overlap (6-1069:5-1057) 10 20 30 40 50 60 pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN :. . ::. .:: ::. : .: . ... : : : ..: XP_011 MAKRKEENFSSPKNAKR--PRQEELEDFDKDGDEDECKGTTLTAAEV--GIIESIHLKN 10 20 30 40 50 70 80 90 100 110 pF1KA0 FLTYDICEVSP---GPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRG :. ... ..: : ..:..:: ::.:::... :. .::.:. . .:.... ::: : XP_011 FMCHSM--LGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGRAVATNRGSSLKGFVKDG 60 70 80 90 100 110 120 130 140 150 160 pF1KA0 CSRGMVEIEL-------FRAS--GN-LVITREIDVAKNQSFWFINKKSTTQKIVEEKVAA . . . : : :.:: :: ..: ..:.. ..:. . ::.: ..: . XP_011 QNSADISITLRNRGDDAFKASVYGNSILIQQHISIDGSRSYKL---KSATGSVVSTRKEE 120 130 140 150 160 170 170 180 190 200 210 220 pF1KA0 LNIQVGNLCQFLPQDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLET : .. : .: .. : : ...: .. : ..: : :. : :: :.. XP_011 L---IAILDHF----NIQFFMKATQLEQMK---------EDYSYIMETKE-RTKE-QIHQ 180 190 200 210 230 240 250 260 270 280 pF1KA0 SCKEKTEYLQKMVQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEY----E . .. :: .. :...::. :.. . : .: : :. . :. ...... . XP_011 GEERLTELKRQCVEKEERF-QSIAGLSTMKTNL---ESLKHEMAWAVVNEIEKQLNAIRD 220 230 240 250 260 290 300 310 320 330 340 pF1KA0 EVKLVRDRVKEEVRKLKEGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQ-KQ ..:. .::. . ::..: :. :..: :.. .... .... . . . . .: : XP_011 NIKIGEDRAARLDRKMEEQQV----RLNEAEQKYKDIQDKLEKISEETNARAPECMALKA 270 280 290 300 310 320 350 360 370 380 390 pF1KA0 DVIERKDKHIEE-------LQQALIVKQNEELDRQRRIGNTRKMIED-LQNE-LKTTENC ::. .: . : :.. .:...: . .:: . .: .. :. : :. .. XP_011 DVVAKKRAYNEAEVLYNRSLNEYKALKKDDE-QLCKRIEELKKSTDQSLEPERLERQKKI 330 340 350 360 370 380 400 410 420 430 440 pF1KA0 ENLQPQIDAITNDLRRIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIVRFDN-----L :. .. :. :. ...: . : ..:. ...:. .: : . ... : XP_011 SWLKERVKAFQNQENSVNQEIEQFQQAIEKDKEEHGKIKREELDVK-HALSYNQRQLKEL 390 400 410 420 430 440 450 460 470 480 490 500 pF1KA0 MNQKEDKLRQRFRDTYDAVLWLRNN---RDKFKQRVCEPIMLTINMKDNKNAKYIENHIP ..: :.:. :: . :.: .. . .: . :. :...: . : ::. . XP_011 KDSKTDRLK-RFGPNVPALLEAIDDAYRQGHFTYKPVGPLGACIHLRDPELALAIESCL- 450 460 470 480 490 500 510 520 530 540 550 560 pF1KA0 SNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIAPK---SSYADKAPSRSLNELKQYGF .. :.:. ... : .:. . :.. . .. : : . .. . . : XP_011 KGLLQAYCCHNHADERVLQALM---KRFYLPGTSRPPIIVSEFRNEIYDVRHRAAYHPDF 510 520 530 540 550 570 580 590 600 610 pF1KA0 FSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERIERVIQETR----LKQIYTAEEK . : : : . : . :. : . ... : :.: . .. .::. XP_011 PTVLTALEIDNAVVANSLIDMRGIETVLLIKNNSVARA--VMQSQKPPKNCREAFTADGD 560 570 580 590 600 610 620 630 640 650 660 670 pF1KA0 YVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLKEIHRKLQAVDSGLIALRE : .:: : :: : ::. :: : ::..... .. ... : ::.. XP_011 QVFAGRYYS----SENTRPK---FLSRDVDSEIS-DLENEVENKTAQILNLQQHLSALEK 620 630 640 650 660 680 690 700 710 720 730 pF1KA0 TSKHLEHKDNELRQKKKELLER-KTKKRQLEQKISSKLGSLKLMEQ-------DTCNLEE :: :: :::.: . . ..:..:: .... .. .:. : .::. XP_011 DIKH-----NE------ELLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLED 670 680 690 700 710 740 750 760 770 780 pF1KA0 EERKASTKIKEI--NVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE--KNKLES : .. ..:.: . .... : : . .:: . . . . . ... . ... :..:. XP_011 EAQENKSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQLSELADPLKDELNL 720 730 740 750 760 770 790 800 810 820 830 pF1KA0 DYMAASSQLR-------LTEQHFIELDENRQRLLQKCKEL---MKRARQVCNLGAEQTLP ...: : ..:. :......: .: ::: :..:::.: : XP_011 ADSEVDNQKRGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQIC--------P 780 790 800 810 820 840 850 860 870 880 890 pF1KA0 QEYQTQ-VPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTI--VQEY .. ... .: . . . : . .: . . . .. . . . :. . .... XP_011 ERIEVEKSASILDKEINRLRQKIQAEHASHGDREEIMRQYQEARETYLDLDSKVRTLKKF 830 840 850 860 870 880 900 910 920 930 940 950 pF1KA0 TKREEEIEQLTEELKGKKVELDQYRENISQVKERWLN--PLKELVEKINEKFSNFFSSMQ : :: . ...: . .. ..:.. . ..: .. :. . . :.:..:. XP_011 IKLLGEI--MEHRFKTYQ-QFRSFRQKNKPNLYYYINLFQMQCLTLRCKLYFDNLLSQRA 890 900 910 920 930 940 960 970 980 990 1000 1010 pF1KA0 CAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELN :.... .:: .: .. ... .... . :::::: ::. ....: . XP_011 YCGKMNFDHKNET----LSISVQPGEGNKAAFNDM--RALSGGERSFSTVCFILSLWSIA 950 960 970 980 990 1020 1030 1040 1050 1060 1070 pF1KA0 RCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFV . ::: .::.. :: .:.: ....... : .. :....::. ...:: :. . .: XP_011 ESPFRCLDEFDVYMDMVNRRIAMDLILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRM 1000 1010 1020 1030 1040 1050 1080 1090 1100 pF1KA0 YNGPHMLEPNTWNLKAFQRRRRRITFTQPS XP_011 SDPERGQTTLPFRPVTQEEDDDQR 1060 1070 1080 >>XP_016860403 (OMIM: 609387) PREDICTED: structural main (1110 aa) initn: 371 init1: 187 opt: 414 Z-score: 237.4 bits: 55.7 E(85289): 1.7e-06 Smith-Waterman score: 586; 21.5% identity (54.9% similar) in 1143 aa overlap (6-1069:5-1084) 10 20 30 40 50 60 pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN :. . ::. .:: ::. : .: . ... : : : ..: XP_016 MAKRKEENFSSPKNAKR--PRQEELEDFDKDGDEDECKGTTLTAAEV--GIIESIHLKN 10 20 30 40 50 70 80 90 100 110 pF1KA0 FLTYDICEVSP---GPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRG :. ... ..: : ..:..:: ::.:::... :. .::.:. . .:.... ::: : XP_016 FMCHSM--LGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGRAVATNRGSSLKGFVKDG 60 70 80 90 100 110 120 130 140 150 160 pF1KA0 CSRGMVEIEL-------FRAS--GN-LVITREIDVAKNQSFWFINKKSTTQKIV----EE . . . : : :.:: :: ..: ..:.. ..:. . ::.: ..: :: XP_016 QNSADISITLRNRGDDAFKASVYGNSILIQQHISIDGSRSYKL---KSATGSVVSTRKEE 120 130 140 150 160 170 170 180 190 200 210 pF1KA0 KVAAL---NIQVGNLCQFLPQDKVGEFAKLSKIE--LLEATEKSIGPPEMHKYHCELKNL .: : :::: : . : :. .: . :: : . :. .:.. . . . XP_016 LIAILDHFNIQVDNPVSVLTQEMSKQFLQ-SKNEGDKYKFFMKATQLEQMKEDYSYIMET 180 190 200 210 220 220 230 240 250 260 270 pF1KA0 REKEK-QLETSCKEKTEYLQKMVQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYEN .:. : :.. . .. :: .. :...::. :.. . : .: : :. . :. .. XP_016 KERTKEQIHQGEERLTELKRQCVEKEERF-QSIAGLSTMKTNL---ESLKHEMAWAVVNE 230 240 250 260 270 280 280 290 300 310 320 330 pF1KA0 VRQEY----EEVKLVRDRVKEEVRKLKEGQIPITCRIEEMENERHNLEARIKEKATDIKE .... ...:. .::. . ::..: :. :..: :.. .... .... . . . XP_016 IEKQLNAIRDNIKIGEDRAARLDRKMEEQQV----RLNEAEQKYKDIQDKLEKISEETNA 290 300 310 320 330 340 340 350 360 370 380 pF1KA0 ASQKCKQ-KQDVIERKDKHIEE-------LQQALIVKQNEELDRQRRIGNTRKMIED-LQ . .: : ::. .: . : :.. .:...: . .:: . .: .. :. XP_016 RAPECMALKADVVAKKRAYNEAEVLYNRSLNEYKALKKDDE-QLCKRIEELKKSTDQSLE 350 360 370 380 390 400 390 400 410 420 430 440 pF1KA0 NE-LKTTENCENLQPQIDAITNDLRRIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIV : :. .. :. .. :. :. ...: . : ..:. ...:. .: : . XP_016 PERLERQKKISWLKERVKAFQNQENSVNQEIEQFQQAIEKDKEEHGKIKREELDVK-HAL 410 420 430 440 450 450 460 470 480 490 pF1KA0 RFDN-----LMNQKEDKLRQRFRDTYDAVLWLRNN---RDKFKQRVCEPIMLTINMKDNK ... : ..: :.:. :: . :.: .. . .: . :. :...: . XP_016 SYNQRQLKELKDSKTDRLK-RFGPNVPALLEAIDDAYRQGHFTYKPVGPLGACIHLRDPE 460 470 480 490 500 510 500 510 520 530 540 550 pF1KA0 NAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIAPK---SSYADKAPSR : ::. . .. :.:. ... : .:. . :.. . .. : : . .. . XP_016 LALAIESCL-KGLLQAYCCHNHADERVLQALM---KRFYLPGTSRPPIIVSEFRNEIYDV 520 530 540 550 560 570 560 570 580 590 600 pF1KA0 SLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERIERVIQETR---- . : . : : : . : . :. : . ... : :.: . XP_016 RHRAAYHPDFPTVLTALEIDNAVVANSLIDMRGIETVLLIKNNSVARA--VMQSQKPPKN 580 590 600 610 620 630 610 620 630 640 650 660 pF1KA0 LKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLKEIHRKLQA .. .::. : .:: : :: : ::. :: : ::..... .. XP_016 CREAFTADGDQVFAGRYYS----SENTRPK---FLSRDVDSEIS-DLENEVENKTAQILN 640 650 660 670 680 670 680 690 700 710 720 pF1KA0 VDSGLIALRETSKHLEHKDNELRQKKKELLER-KTKKRQLEQKISSKLGSLKLMEQ---- ... : ::.. :: :: :::.: . . ..:..:: .... .. .:. XP_016 LQQHLSALEKDIKH-----NE------ELLKRCQLHYKELKMKIRKNISEIRELENIEEH 690 700 710 720 730 730 740 750 760 770 pF1KA0 ---DTCNLEEEERKASTKIKEI--NVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVI : .::.: .. ..:.: . .... : : . .:: . . . . . ... . . XP_016 QSVDIATLEDEAQENKSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQLSEL 740 750 760 770 780 790 780 790 800 810 820 pF1KA0 SE--KNKLESDYMAASSQLR-------LTEQHFIELDENRQRLLQKCKEL---MKRARQV .. :..:. ...: : ..:. :......: .: ::: :..:::. XP_016 ADPLKDELNLADSEVDNQKRGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQI 800 810 820 830 840 850 830 840 850 860 870 880 pF1KA0 CNLGAEQTLPQEYQTQ-VPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGL : :.. ... .: . . . : . .: . . . .. . . . : XP_016 C--------PERIEVEKSASILDKEINRLRQKIQAEHASHGDREEIMRQYQEARETYLDL 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 NPTI--VQEYTKREEEIEQLTEELKGKKVELDQYRENISQVKERWLN--PLKELVEKINE . . .... : :: . ...: . .. ..:.. . ..: .. :. . . XP_016 DSKVRTLKKFIKLLGEI--MEHRFKTYQ-QFRSFRQKNKPNLYYYINLFQMQCLTLRCKL 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 KFSNFFSSMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTM :.:..:. :.... .:: .: .. ... .... . :::::: ::. XP_016 YFDNLLSQRAYCGKMNFDHKNET----LSISVQPGEGNKAAFNDM--RALSGGERSFSTV 970 980 990 1000 1010 1010 1020 1030 1040 1050 1060 pF1KA0 LYLMALQELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLP ....: . . ::: .::.. :: .:.: ....... : .. :....::. ...:: XP_016 CFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDLILKMADSQRFRQFILLTPQSMSSLP 1020 1030 1040 1050 1060 1070 1070 1080 1090 1100 pF1KA0 YSEKMTVLFVYNGPHMLEPNTWNLKAFQRRRRRITFTQPS :. . .: XP_016 SSKLIRILRMSDPERGQTTLPFRPVTQEEDDDQR 1080 1090 1100 1110 1101 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:49:31 2016 done: Thu Nov 3 09:49:33 2016 Total Scan time: 15.650 Total Display time: 0.510 Function used was FASTA [36.3.4 Apr, 2011]