FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0597, 910 aa 1>>>pF1KA0597 910 - 910 aa - 910 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5384+/-0.00101; mu= 15.9611+/- 0.061 mean_var=123.4209+/-24.502, 0's: 0 Z-trim(108.8): 30 B-trim: 3 in 1/49 Lambda= 0.115446 statistics sampled from 10418 (10439) to 10418 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.321), width: 16 Scan time: 4.610 The best scores are: opt bits E(32554) CCDS34135.1 MARCH6 gene_id:10299|Hs108|chr5 ( 910) 6182 1041.7 0 CCDS59487.1 MARCH6 gene_id:10299|Hs108|chr5 ( 862) 5380 908.1 0 CCDS59488.1 MARCH6 gene_id:10299|Hs108|chr5 ( 805) 5369 906.2 0 >>CCDS34135.1 MARCH6 gene_id:10299|Hs108|chr5 (910 aa) initn: 6182 init1: 6182 opt: 6182 Z-score: 5569.0 bits: 1041.7 E(32554): 0 Smith-Waterman score: 6182; 100.0% identity (100.0% similar) in 910 aa overlap (1-910:1-910) 10 20 30 40 50 60 pF1KA0 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 WLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 WLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 LIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 PQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 MQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGS 850 860 870 880 890 900 910 pF1KA0 SPPPPQSSQE :::::::::: CCDS34 SPPPPQSSQE 910 >>CCDS59487.1 MARCH6 gene_id:10299|Hs108|chr5 (862 aa) initn: 5373 init1: 5373 opt: 5380 Z-score: 4847.4 bits: 908.1 E(32554): 0 Smith-Waterman score: 5736; 94.6% identity (94.6% similar) in 910 aa overlap (1-910:1-862) 10 20 30 40 50 60 pF1KA0 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT ::: :::::::: CCDS59 FTP------------------------------------------------SRIYKCLFT 70 130 140 150 160 170 180 pF1KA0 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA 80 90 100 110 120 130 190 200 210 220 230 240 pF1KA0 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED 140 150 160 170 180 190 250 260 270 280 290 300 pF1KA0 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF 200 210 220 230 240 250 310 320 330 340 350 360 pF1KA0 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH 260 270 280 290 300 310 370 380 390 400 410 420 pF1KA0 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT 320 330 340 350 360 370 430 440 450 460 470 480 pF1KA0 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF 380 390 400 410 420 430 490 500 510 520 530 540 pF1KA0 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL 440 450 460 470 480 490 550 560 570 580 590 600 pF1KA0 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV 500 510 520 530 540 550 610 620 630 640 650 660 pF1KA0 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGR 560 570 580 590 600 610 670 680 690 700 710 720 pF1KA0 WLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 WLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKT 620 630 640 650 660 670 730 740 750 760 770 780 pF1KA0 LIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG 680 690 700 710 720 730 790 800 810 820 830 840 pF1KA0 PQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 PQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAE 740 750 760 770 780 790 850 860 870 880 890 900 pF1KA0 MQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGS 800 810 820 830 840 850 910 pF1KA0 SPPPPQSSQE :::::::::: CCDS59 SPPPPQSSQE 860 >>CCDS59488.1 MARCH6 gene_id:10299|Hs108|chr5 (805 aa) initn: 5369 init1: 5369 opt: 5369 Z-score: 4837.9 bits: 906.2 E(32554): 0 Smith-Waterman score: 5369; 100.0% identity (100.0% similar) in 798 aa overlap (113-910:8-805) 90 100 110 120 130 140 pF1KA0 VTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLAD :::::::::::::::::::::::::::::: CCDS59 MDTAEEGRIYKCLFTGSVSSLLTLPLDMLSTENLLAD 10 20 30 150 160 170 180 190 200 pF1KA0 CLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPAGGNGAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 CLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPAGGNGAEN 40 50 60 70 80 90 210 220 230 240 250 260 pF1KA0 VAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMNWNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 VAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMNWNA 100 110 120 130 140 150 270 280 290 300 310 320 pF1KA0 LEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFE 160 170 180 190 200 210 330 340 350 360 370 380 pF1KA0 EHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFHRSRRLLGVCYIVVKVSLLVVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 EHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFHRSRRLLGVCYIVVKVSLLVVVE 220 230 240 250 260 270 390 400 410 420 430 440 pF1KA0 IGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 IGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLL 280 290 300 310 320 330 450 460 470 480 490 500 pF1KA0 REVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 REVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRII 340 350 360 370 380 390 510 520 530 540 550 560 pF1KA0 KSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 KSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGY 400 410 420 430 440 450 570 580 590 600 610 620 pF1KA0 LLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGEGLHAAHQAILQQGGPVGFQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGEGLHAAHQAILQQGGPVGFQP 460 470 480 490 500 510 630 640 650 660 670 680 pF1KA0 YRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 YRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGL 520 530 540 550 560 570 690 700 710 720 730 740 pF1KA0 YVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 YVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELV 580 590 600 610 620 630 750 760 770 780 790 800 pF1KA0 IVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 IVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDL 640 650 660 670 680 690 810 820 830 840 850 860 pF1KA0 HYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 HYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAI 700 710 720 730 740 750 870 880 890 900 910 pF1KA0 LSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE :::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE 760 770 780 790 800 910 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:50:14 2016 done: Thu Nov 3 09:50:14 2016 Total Scan time: 4.610 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]