FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0602, 904 aa 1>>>pF1KA0602 904 - 904 aa - 904 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0288+/-0.000349; mu= 5.6057+/- 0.022 mean_var=178.6919+/-36.429, 0's: 0 Z-trim(120.3): 34 B-trim: 1437 in 2/59 Lambda= 0.095945 statistics sampled from 35352 (35386) to 35352 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.733), E-opt: 0.2 (0.415), width: 16 Scan time: 12.540 The best scores are: opt bits E(85289) NP_001094383 (OMIM: 610423) phosphofurin acidic cl ( 904) 5981 840.3 0 XP_006720153 (OMIM: 610423) PREDICTED: phosphofuri ( 905) 5969 838.7 0 XP_016876595 (OMIM: 610423) PREDICTED: phosphofuri ( 900) 5939 834.5 0 XP_016876594 (OMIM: 610423) PREDICTED: phosphofuri ( 901) 5927 832.9 0 XP_016876597 (OMIM: 610423) PREDICTED: phosphofuri ( 896) 5909 830.4 0 XP_016876596 (OMIM: 610423) PREDICTED: phosphofuri ( 897) 5897 828.7 0 XP_016876601 (OMIM: 610423) PREDICTED: phosphofuri ( 838) 5530 777.9 0 XP_016876598 (OMIM: 610423) PREDICTED: phosphofuri ( 893) 4424 624.8 5.6e-178 XP_006720154 (OMIM: 610423) PREDICTED: phosphofuri ( 894) 4417 623.9 1.1e-177 NP_056012 (OMIM: 610423) phosphofurin acidic clust ( 889) 4368 617.1 1.2e-175 XP_016876599 (OMIM: 610423) PREDICTED: phosphofuri ( 890) 4356 615.4 3.8e-175 XP_016876600 (OMIM: 610423) PREDICTED: phosphofuri ( 822) 3929 556.3 2.2e-157 XP_006720155 (OMIM: 610423) PREDICTED: phosphofuri ( 881) 2996 427.2 1.8e-118 NP_060496 (OMIM: 607492,615009) phosphofurin acidi ( 963) 2331 335.1 9.7e-91 XP_011543466 (OMIM: 607492,615009) PREDICTED: phos ( 850) 2184 314.8 1.2e-84 XP_011543464 (OMIM: 607492,615009) PREDICTED: phos ( 856) 2184 314.8 1.2e-84 NP_001230056 (OMIM: 610423) phosphofurin acidic cl ( 814) 1491 218.8 8.4e-56 >>NP_001094383 (OMIM: 610423) phosphofurin acidic cluste (904 aa) initn: 5981 init1: 5981 opt: 5981 Z-score: 4481.0 bits: 840.3 E(85289): 0 Smith-Waterman score: 5981; 100.0% identity (100.0% similar) in 904 aa overlap (1-904:1-904) 10 20 30 40 50 60 pF1KA0 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 ESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHS 850 860 870 880 890 900 pF1KA0 KATF :::: NP_001 KATF >>XP_006720153 (OMIM: 610423) PREDICTED: phosphofurin ac (905 aa) initn: 5967 init1: 3531 opt: 5969 Z-score: 4472.0 bits: 838.7 E(85289): 0 Smith-Waterman score: 5969; 99.9% identity (99.9% similar) in 905 aa overlap (1-904:1-905) 10 20 30 40 50 60 pF1KA0 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 GGRQPSDSVSDTVAL-GVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVI ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: XP_006 GGRQPSDSVSDTVALQGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 PSTRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSTRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYD 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 QLNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 QRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVA 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA0 RYLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RYLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEA 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA0 MLTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGT 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA0 LSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDA 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA0 EKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKD 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA0 VESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGH 850 860 870 880 890 900 900 pF1KA0 SKATF ::::: XP_006 SKATF >>XP_016876595 (OMIM: 610423) PREDICTED: phosphofurin ac (900 aa) initn: 3138 init1: 3068 opt: 5939 Z-score: 4449.6 bits: 834.5 E(85289): 0 Smith-Waterman score: 5939; 99.6% identity (99.6% similar) in 904 aa overlap (1-904:1-900) 10 20 30 40 50 60 pF1KA0 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: XP_016 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQ----IPRKTVYDQ 430 440 450 460 470 490 500 510 520 530 540 pF1KA0 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA0 LTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTL 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA0 SSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA0 KKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDV 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 ESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHS 840 850 860 870 880 890 pF1KA0 KATF :::: XP_016 KATF 900 >>XP_016876594 (OMIM: 610423) PREDICTED: phosphofurin ac (901 aa) initn: 5348 init1: 2912 opt: 5927 Z-score: 4440.6 bits: 832.9 E(85289): 0 Smith-Waterman score: 5927; 99.4% identity (99.4% similar) in 905 aa overlap (1-904:1-901) 10 20 30 40 50 60 pF1KA0 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 GGRQPSDSVSDTVAL-GVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVI ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRQPSDSVSDTVALQGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 PSTRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYD :::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_016 PSTRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQ----IPRKTVYD 430 440 450 460 470 480 490 500 510 520 530 pF1KA0 QLNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRI 480 490 500 510 520 530 540 550 560 570 580 590 pF1KA0 QRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVA 540 550 560 570 580 590 600 610 620 630 640 650 pF1KA0 RYLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEA 600 610 620 630 640 650 660 670 680 690 700 710 pF1KA0 MLTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGT 660 670 680 690 700 710 720 730 740 750 760 770 pF1KA0 LSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDA 720 730 740 750 760 770 780 790 800 810 820 830 pF1KA0 EKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKD 780 790 800 810 820 830 840 850 860 870 880 890 pF1KA0 VESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGH 840 850 860 870 880 890 900 pF1KA0 SKATF ::::: XP_016 SKATF 900 >>XP_016876597 (OMIM: 610423) PREDICTED: phosphofurin ac (896 aa) initn: 5921 init1: 4380 opt: 5909 Z-score: 4427.2 bits: 830.4 E(85289): 0 Smith-Waterman score: 5909; 99.1% identity (99.1% similar) in 904 aa overlap (1-904:1-896) 10 20 30 40 50 60 pF1KA0 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSI- 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -------QQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA0 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA0 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA0 LTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTL 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA0 SSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA0 KKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDV 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 ESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHS 840 850 860 870 880 890 pF1KA0 KATF :::: XP_016 KATF >>XP_016876596 (OMIM: 610423) PREDICTED: phosphofurin ac (897 aa) initn: 5907 init1: 3531 opt: 5897 Z-score: 4418.2 bits: 828.7 E(85289): 0 Smith-Waterman score: 5897; 99.0% identity (99.0% similar) in 905 aa overlap (1-904:1-897) 10 20 30 40 50 60 pF1KA0 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSI- 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -------QQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 300 310 320 330 340 350 370 380 390 400 410 pF1KA0 GGRQPSDSVSDTVAL-GVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVI ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRQPSDSVSDTVALQGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVI 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 PSTRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSTRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYD 420 430 440 450 460 470 480 490 500 510 520 530 pF1KA0 QLNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRI 480 490 500 510 520 530 540 550 560 570 580 590 pF1KA0 QRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVA 540 550 560 570 580 590 600 610 620 630 640 650 pF1KA0 RYLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEA 600 610 620 630 640 650 660 670 680 690 700 710 pF1KA0 MLTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGT 660 670 680 690 700 710 720 730 740 750 760 770 pF1KA0 LSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDA 720 730 740 750 760 770 780 790 800 810 820 830 pF1KA0 EKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKD 780 790 800 810 820 830 840 850 860 870 880 890 pF1KA0 VESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGH 840 850 860 870 880 890 900 pF1KA0 SKATF ::::: XP_016 SKATF >>XP_016876601 (OMIM: 610423) PREDICTED: phosphofurin ac (838 aa) initn: 5528 init1: 3531 opt: 5530 Z-score: 4144.1 bits: 777.9 E(85289): 0 Smith-Waterman score: 5530; 99.9% identity (99.9% similar) in 838 aa overlap (68-904:1-838) 40 50 60 70 80 90 pF1KA0 VPRLCSLTLKKLVVFKELEKELISVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFS :::::::::::::::::::::::::::::: XP_016 MQGSKRILRSHEIVLPPSGQVETDLALTFS 10 20 30 100 110 120 130 140 150 pF1KA0 LQYPHFLKREGNKLQIMLQRRKRYKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQYPHFLKREGNKLQIMLQRRKRYKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KA0 SIKEAPVKAAEIWIASLSSQPIDHEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIKEAPVKAAEIWIASLSSQPIDHEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAV 100 110 120 130 140 150 220 230 240 250 260 270 pF1KA0 QGQDLDEDDFDVGKPKKQRRSIVRTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGQDLDEDDFDVGKPKKQRRSIVRTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAE 160 170 180 190 200 210 280 290 300 310 320 330 pF1KA0 HIPEAEEDLDLLYDTLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HIPEAEEDLDLLYDTLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGS 220 230 240 250 260 270 340 350 360 370 380 390 pF1KA0 IHSARSHKEPPSPADVPEKTRSLGGRQPSDSVSDTVAL-GVPGPREHPGQPEDSPEAEAS :::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_016 IHSARSHKEPPSPADVPEKTRSLGGRQPSDSVSDTVALQGVPGPREHPGQPEDSPEAEAS 280 290 300 310 320 330 400 410 420 430 440 450 pF1KA0 TLDVFTERLPPSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQAARPQNERANSLDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLDVFTERLPPSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQAARPQNERANSLDN 340 350 360 370 380 390 460 470 480 490 500 510 pF1KA0 ERCPDARSQLQVQLQIPRKTVYDQLNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERCPDARSQLQVQLQIPRKTVYDQLNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHT 400 410 420 430 440 450 520 530 540 550 560 570 pF1KA0 LPVVCTCSPADVQAAFSTIVSRIQRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPVVCTCSPADVQAAFSTIVSRIQRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLS 460 470 480 490 500 510 580 590 600 610 620 630 pF1KA0 HKTPDWLGYMRFLVIPLGSHPVARYLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKTPDWLGYMRFLVIPLGSHPVARYLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPD 520 530 540 550 560 570 640 650 660 670 680 690 pF1KA0 IVSRITQYIAGANCAHQLPIAEAMLTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVSRITQYIAGANCAHQLPIAEAMLTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKV 580 590 600 610 620 630 700 710 720 730 740 750 pF1KA0 GIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVG 640 650 660 670 680 690 760 770 780 790 800 810 pF1KA0 AELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMS 700 710 720 730 740 750 820 830 840 850 860 870 pF1KA0 MTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDV 760 770 780 790 800 810 880 890 900 pF1KA0 KFFQLAAQWSSHVKHFPICIFGHSKATF :::::::::::::::::::::::::::: XP_016 KFFQLAAQWSSHVKHFPICIFGHSKATF 820 830 >>XP_016876598 (OMIM: 610423) PREDICTED: phosphofurin ac (893 aa) initn: 5886 init1: 4409 opt: 4424 Z-score: 3316.3 bits: 624.8 E(85289): 5.6e-178 Smith-Waterman score: 5868; 98.8% identity (98.8% similar) in 904 aa overlap (1-904:1-893) 10 20 30 40 50 60 pF1KA0 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTL :::::: ::::::::::::::::::::::::::::::::::::::::::: XP_016 LTYKQK-----------SPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTL 670 680 690 700 730 740 750 760 770 780 pF1KA0 SSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE 710 720 730 740 750 760 790 800 810 820 830 840 pF1KA0 KKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDV 770 780 790 800 810 820 850 860 870 880 890 900 pF1KA0 ESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHS 830 840 850 860 870 880 pF1KA0 KATF :::: XP_016 KATF 890 >>XP_006720154 (OMIM: 610423) PREDICTED: phosphofurin ac (894 aa) initn: 5872 init1: 2450 opt: 4417 Z-score: 3311.0 bits: 623.9 E(85289): 1.1e-177 Smith-Waterman score: 5856; 98.7% identity (98.7% similar) in 905 aa overlap (1-904:1-894) 10 20 30 40 50 60 pF1KA0 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 GGRQPSDSVSDTVAL-GVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVI ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: XP_006 GGRQPSDSVSDTVALQGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 PSTRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSTRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYD 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 QLNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 QRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVA 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA0 RYLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RYLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEA 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA0 MLTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGT ::::::: :::::::::::::::::::::::::::::::::::::::::: XP_006 MLTYKQK-----------SPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGT 670 680 690 700 720 730 740 750 760 770 pF1KA0 LSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDA 710 720 730 740 750 760 780 790 800 810 820 830 pF1KA0 EKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKD 770 780 790 800 810 820 840 850 860 870 880 890 pF1KA0 VESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGH 830 840 850 860 870 880 900 pF1KA0 SKATF ::::: XP_006 SKATF 890 >>NP_056012 (OMIM: 610423) phosphofurin acidic cluster s (889 aa) initn: 4545 init1: 3068 opt: 4368 Z-score: 3274.4 bits: 617.1 E(85289): 1.2e-175 Smith-Waterman score: 5826; 98.3% identity (98.3% similar) in 904 aa overlap (1-904:1-889) 10 20 30 40 50 60 pF1KA0 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_056 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQ----IPRKTVYDQ 430 440 450 460 470 490 500 510 520 530 540 pF1KA0 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA0 LTYKQKRKKHFHFDFTLSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTL :::::: ::::::::::::::::::::::::::::::::::::::::::: NP_056 LTYKQK-----------SPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTL 660 670 680 690 700 730 740 750 760 770 780 pF1KA0 SSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE 710 720 730 740 750 760 790 800 810 820 830 840 pF1KA0 KKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDV 770 780 790 800 810 820 850 860 870 880 890 900 pF1KA0 ESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ESKSQCIEGISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHS 830 840 850 860 870 880 pF1KA0 KATF :::: NP_056 KATF 904 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:24:37 2016 done: Wed Nov 2 19:24:39 2016 Total Scan time: 12.540 Total Display time: 0.320 Function used was FASTA [36.3.4 Apr, 2011]