FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0612, 1797 aa 1>>>pF1KA0612 1797 - 1797 aa - 1797 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.8621+/-0.000421; mu= -13.9515+/- 0.026 mean_var=520.7389+/-105.332, 0's: 0 Z-trim(124.6): 61 B-trim: 66 in 1/60 Lambda= 0.056204 statistics sampled from 46504 (46574) to 46504 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.546), width: 16 Scan time: 23.750 The best scores are: opt bits E(85289) NP_077729 (OMIM: 610764) peripheral-type benzodiaz (1797) 12234 1008.0 0 XP_006722238 (OMIM: 610764) PREDICTED: peripheral- (1847) 12169 1002.8 0 NP_004749 (OMIM: 610764) peripheral-type benzodiaz (1857) 10982 906.5 0 XP_016880817 (OMIM: 610764) PREDICTED: peripheral- (1804) 10933 902.5 0 XP_016880815 (OMIM: 610764) PREDICTED: peripheral- (1879) 10920 901.5 0 XP_016880816 (OMIM: 610764) PREDICTED: peripheral- (1868) 10917 901.3 0 XP_006722236 (OMIM: 610764) PREDICTED: peripheral- (1907) 10917 901.3 0 XP_006722237 (OMIM: 610764) PREDICTED: peripheral- (1900) 10851 895.9 0 NP_001248764 (OMIM: 610764) peripheral-type benzod (1848) 10013 827.9 0 XP_005257864 (OMIM: 610764) PREDICTED: peripheral- (1898) 10013 828.0 0 XP_006722241 (OMIM: 610764) PREDICTED: peripheral- (1467) 9643 797.9 0 XP_006722240 (OMIM: 610764) PREDICTED: peripheral- (1467) 9643 797.9 0 XP_011523774 (OMIM: 610764) PREDICTED: peripheral- (1411) 9297 769.8 0 XP_011523773 (OMIM: 610764) PREDICTED: peripheral- (1428) 8793 728.9 8.1e-209 XP_016880821 (OMIM: 610764) PREDICTED: peripheral- (1517) 8322 690.8 2.7e-197 XP_016880818 (OMIM: 610764) PREDICTED: peripheral- (1627) 7084 590.4 4.6e-167 XP_016880819 (OMIM: 610764) PREDICTED: peripheral- (1577) 7070 589.3 9.9e-167 XP_016880820 (OMIM: 610764) PREDICTED: peripheral- (1568) 7069 589.2 1e-166 XP_006722239 (OMIM: 610764) PREDICTED: peripheral- (1630) 5993 501.9 2e-140 XP_016880823 (OMIM: 610764) PREDICTED: peripheral- (1240) 4307 365.1 2.3e-99 XP_016880822 (OMIM: 610764) PREDICTED: peripheral- (1291) 3055 263.6 8.5e-69 XP_011536410 (OMIM: 611602) PREDICTED: RIMS-bindin ( 874) 1238 116.2 1.4e-24 XP_011536409 (OMIM: 611602) PREDICTED: RIMS-bindin ( 875) 1238 116.2 1.4e-24 XP_016874601 (OMIM: 611602) PREDICTED: RIMS-bindin ( 753) 1228 115.3 2.2e-24 NP_056487 (OMIM: 612699) RIMS-binding protein 3A [ (1639) 627 66.8 1.9e-09 NP_001122105 (OMIM: 612701) RIMS-binding protein 3 (1639) 620 66.3 2.8e-09 NP_001122107 (OMIM: 612700) RIMS-binding protein 3 (1639) 614 65.8 3.9e-09 XP_011536406 (OMIM: 611602) PREDICTED: RIMS-bindin (1362) 442 51.8 5.4e-05 XP_011536404 (OMIM: 611602) PREDICTED: RIMS-bindin (1362) 442 51.8 5.4e-05 XP_016874594 (OMIM: 611602) PREDICTED: RIMS-bindin (1362) 442 51.8 5.4e-05 XP_011536405 (OMIM: 611602) PREDICTED: RIMS-bindin (1429) 442 51.8 5.6e-05 NP_056162 (OMIM: 611602) RIMS-binding protein 2 [H (1052) 433 51.0 7.3e-05 XP_016874599 (OMIM: 611602) PREDICTED: RIMS-bindin (1069) 433 51.0 7.4e-05 XP_016874600 (OMIM: 611602) PREDICTED: RIMS-bindin (1069) 433 51.0 7.4e-05 XP_016874598 (OMIM: 611602) PREDICTED: RIMS-bindin (1123) 433 51.0 7.7e-05 XP_016874596 (OMIM: 611602) PREDICTED: RIMS-bindin (1123) 433 51.0 7.7e-05 XP_016874597 (OMIM: 611602) PREDICTED: RIMS-bindin (1123) 433 51.0 7.7e-05 XP_016874595 (OMIM: 611602) PREDICTED: RIMS-bindin (1190) 433 51.0 8e-05 XP_011536408 (OMIM: 611602) PREDICTED: RIMS-bindin (1191) 433 51.0 8e-05 XP_011536407 (OMIM: 611602) PREDICTED: RIMS-bindin (1244) 433 51.0 8.3e-05 >>NP_077729 (OMIM: 610764) peripheral-type benzodiazepin (1797 aa) initn: 12234 init1: 12234 opt: 12234 Z-score: 5376.5 bits: 1008.0 E(85289): 0 Smith-Waterman score: 12234; 99.7% identity (99.8% similar) in 1797 aa overlap (1-1797:1-1797) 10 20 30 40 50 60 pF1KA0 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RKLQETNLRVEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 RKLQETNLRVEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPERVELHGFHICVNGELRQALGPGAP ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_077 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 PKAVLENLDLRAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 PKAVLENLDLWAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQLPAPLGTQEPPGAPPASPSREMP ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: NP_077 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTARTTGPPPKPRRSK :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: NP_077 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTAHTTGPPPKPRRSK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 pF1KA0 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC 1750 1760 1770 1780 1790 >>XP_006722238 (OMIM: 610764) PREDICTED: peripheral-type (1847 aa) initn: 12169 init1: 12169 opt: 12169 Z-score: 5347.8 bits: 1002.8 E(85289): 0 Smith-Waterman score: 12169; 99.7% identity (99.8% similar) in 1788 aa overlap (1-1788:1-1788) 10 20 30 40 50 60 pF1KA0 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RKLQETNLRVEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKLQETNLRVEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPERVELHGFHICVNGELRQALGPGAP ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: XP_006 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 PKAVLENLDLRAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PKAVLENLDLWAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQLPAPLGTQEPPGAPPASPSREMP ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_006 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTARTTGPPPKPRRSK :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: XP_006 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTAHTTGPPPKPRRSK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 pF1KA0 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC :::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQDWGCTTQGSPGP 1750 1760 1770 1780 1790 1800 XP_006 PGGPCTPSSGSAPRIERGEPQGRSEKVWGFFSKGKQLLRRLGSGKKE 1810 1820 1830 1840 >>NP_004749 (OMIM: 610764) peripheral-type benzodiazepin (1857 aa) initn: 12220 init1: 10962 opt: 10982 Z-score: 4827.6 bits: 906.5 E(85289): 0 Smith-Waterman score: 11885; 96.4% identity (96.6% similar) in 1829 aa overlap (29-1797:29-1857) 10 20 30 40 50 60 pF1KA0 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES :::::::::::::::::::::::::::::::: NP_004 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA 130 140 150 160 170 180 190 pF1KA0 RKLQETNLRV-------------------------------------------------- :::::::::: NP_004 RKLQETNLRVVSAPLPRPGTSLELCRKALARQRARDLSETASALLAKDKQIAALQRECRE 190 200 210 220 230 240 200 210 220 230 240 pF1KA0 ----------EGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL :::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LQARLTLVGKEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA0 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA0 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA0 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA0 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA0 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA0 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA0 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA0 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA0 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPERVELHGFHICVNGELRQALGPGAP ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_004 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAP 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA0 PKAVLENLDLRAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PKAVLENLDLWAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA0 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA0 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA0 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA0 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQLPAPLGTQEPPGAPPASPSREMP ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: NP_004 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMA 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 1140 pF1KA0 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP 1150 1160 1170 1180 1190 1200 1150 1160 1170 1180 1190 1200 pF1KA0 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI 1210 1220 1230 1240 1250 1260 1210 1220 1230 1240 1250 1260 pF1KA0 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP 1270 1280 1290 1300 1310 1320 1270 1280 1290 1300 1310 1320 pF1KA0 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC 1330 1340 1350 1360 1370 1380 1330 1340 1350 1360 1370 1380 pF1KA0 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS 1390 1400 1410 1420 1430 1440 1390 1400 1410 1420 1430 1440 pF1KA0 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE 1450 1460 1470 1480 1490 1500 1450 1460 1470 1480 1490 1500 pF1KA0 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP 1510 1520 1530 1540 1550 1560 1510 1520 1530 1540 1550 1560 pF1KA0 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL 1570 1580 1590 1600 1610 1620 1570 1580 1590 1600 1610 1620 pF1KA0 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT 1630 1640 1650 1660 1670 1680 1630 1640 1650 1660 1670 1680 pF1KA0 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTARTTGPPPKPRRSK :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: NP_004 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTAHTTGPPPKPRRSK 1690 1700 1710 1720 1730 1740 1690 1700 1710 1720 1730 1740 pF1KA0 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV 1750 1760 1770 1780 1790 1800 1750 1760 1770 1780 1790 pF1KA0 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC 1810 1820 1830 1840 1850 >>XP_016880817 (OMIM: 610764) PREDICTED: peripheral-type (1804 aa) initn: 10933 init1: 10933 opt: 10933 Z-score: 4806.3 bits: 902.5 E(85289): 0 Smith-Waterman score: 11815; 97.3% identity (97.4% similar) in 1788 aa overlap (1-1788:1-1745) 10 20 30 40 50 60 pF1KA0 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA ::::::::::::::::::::::::::: XP_016 RPNLELLRALGELRQRCAILKEENQML--------------------------------- 130 140 190 200 210 220 230 240 pF1KA0 RKLQETNLRVEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ----------EGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL 150 160 170 180 190 250 260 270 280 290 300 pF1KA0 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK 200 210 220 230 240 250 310 320 330 340 350 360 pF1KA0 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA 260 270 280 290 300 310 370 380 390 400 410 420 pF1KA0 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ 320 330 340 350 360 370 430 440 450 460 470 480 pF1KA0 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD 380 390 400 410 420 430 490 500 510 520 530 540 pF1KA0 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK 440 450 460 470 480 490 550 560 570 580 590 600 pF1KA0 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA 500 510 520 530 540 550 610 620 630 640 650 660 pF1KA0 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD 560 570 580 590 600 610 670 680 690 700 710 720 pF1KA0 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP 620 630 640 650 660 670 730 740 750 760 770 780 pF1KA0 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPERVELHGFHICVNGELRQALGPGAP ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: XP_016 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAP 680 690 700 710 720 730 790 800 810 820 830 840 pF1KA0 PKAVLENLDLRAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKAVLENLDLWAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI 740 750 760 770 780 790 850 860 870 880 890 900 pF1KA0 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE 800 810 820 830 840 850 910 920 930 940 950 960 pF1KA0 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KA0 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP 920 930 940 950 960 970 1030 1040 1050 1060 1070 1080 pF1KA0 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQLPAPLGTQEPPGAPPASPSREMP ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_016 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMA 980 990 1000 1010 1020 1030 1090 1100 1110 1120 1130 1140 pF1KA0 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP 1040 1050 1060 1070 1080 1090 1150 1160 1170 1180 1190 1200 pF1KA0 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI 1100 1110 1120 1130 1140 1150 1210 1220 1230 1240 1250 1260 pF1KA0 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP 1160 1170 1180 1190 1200 1210 1270 1280 1290 1300 1310 1320 pF1KA0 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC 1220 1230 1240 1250 1260 1270 1330 1340 1350 1360 1370 1380 pF1KA0 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS 1280 1290 1300 1310 1320 1330 1390 1400 1410 1420 1430 1440 pF1KA0 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE 1340 1350 1360 1370 1380 1390 1450 1460 1470 1480 1490 1500 pF1KA0 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP 1400 1410 1420 1430 1440 1450 1510 1520 1530 1540 1550 1560 pF1KA0 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL 1460 1470 1480 1490 1500 1510 1570 1580 1590 1600 1610 1620 pF1KA0 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT 1520 1530 1540 1550 1560 1570 1630 1640 1650 1660 1670 1680 pF1KA0 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTARTTGPPPKPRRSK :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: XP_016 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTAHTTGPPPKPRRSK 1580 1590 1600 1610 1620 1630 1690 1700 1710 1720 1730 1740 pF1KA0 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV 1640 1650 1660 1670 1680 1690 1750 1760 1770 1780 1790 pF1KA0 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQDWGCTTQGSPGP 1700 1710 1720 1730 1740 1750 XP_016 PGGPCTPSSGSAPRIERGEPQGRSEKVWGFFSKGKQLLRRLGSGKKE 1760 1770 1780 1790 1800 >>XP_016880815 (OMIM: 610764) PREDICTED: peripheral-type (1879 aa) initn: 12420 init1: 10900 opt: 10920 Z-score: 4800.4 bits: 901.5 E(85289): 0 Smith-Waterman score: 11823; 96.4% identity (96.5% similar) in 1822 aa overlap (29-1790:29-1850) 10 20 30 40 50 60 pF1KA0 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES :::::::::::::::::::::::::::::::: XP_016 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA 130 140 150 160 170 180 190 pF1KA0 RKLQETNLRV-------------------------------------------------- :::::::::: XP_016 RKLQETNLRVVSAPLPRPGTSLELCRKALARQRARDLSETASALLAKDKQIAALQRECRE 190 200 210 220 230 240 200 210 220 230 240 pF1KA0 ----------EGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQARLTLVGKEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA0 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA0 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA0 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA0 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA0 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA0 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA0 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA0 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA0 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPERVELHGFHICVNGELRQALGPGAP ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: XP_016 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAP 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA0 PKAVLENLDLRAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKAVLENLDLWAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA0 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA0 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA0 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA0 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQLPAPLGTQEPPGAPPASPSREMP ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_016 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMA 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 1140 pF1KA0 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP 1150 1160 1170 1180 1190 1200 1150 1160 1170 1180 1190 1200 pF1KA0 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI 1210 1220 1230 1240 1250 1260 1210 1220 1230 1240 1250 1260 pF1KA0 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP 1270 1280 1290 1300 1310 1320 1270 1280 1290 1300 1310 1320 pF1KA0 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC 1330 1340 1350 1360 1370 1380 1330 1340 1350 1360 1370 1380 pF1KA0 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS 1390 1400 1410 1420 1430 1440 1390 1400 1410 1420 1430 1440 pF1KA0 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE 1450 1460 1470 1480 1490 1500 1450 1460 1470 1480 1490 1500 pF1KA0 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP 1510 1520 1530 1540 1550 1560 1510 1520 1530 1540 1550 1560 pF1KA0 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL 1570 1580 1590 1600 1610 1620 1570 1580 1590 1600 1610 1620 pF1KA0 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT 1630 1640 1650 1660 1670 1680 1630 1640 1650 1660 1670 1680 pF1KA0 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTARTTGPPPKPRRSK :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: XP_016 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTAHTTGPPPKPRRSK 1690 1700 1710 1720 1730 1740 1690 1700 1710 1720 1730 1740 pF1KA0 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV 1750 1760 1770 1780 1790 1800 1750 1760 1770 1780 1790 pF1KA0 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC :::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQDTPTLGVVSIPP 1810 1820 1830 1840 1850 1860 XP_016 RCLWKPVAQPGPASWVLVP 1870 >>XP_016880816 (OMIM: 610764) PREDICTED: peripheral-type (1868 aa) initn: 11805 init1: 10897 opt: 10917 Z-score: 4799.1 bits: 901.3 E(85289): 0 Smith-Waterman score: 11689; 96.3% identity (96.4% similar) in 1802 aa overlap (47-1788:8-1809) 20 30 40 50 60 70 pF1KA0 EPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEESSKPKGDGSSRPVGGTD : :::::::::::::::::::::::::::: XP_016 METSSRLPIALQLQELRSEESSKPKGDGSSRPVGGTD 10 20 30 80 90 100 110 120 130 pF1KA0 PEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGDRPNLELLRALGELRQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGDRPNLELLRALGELRQR 40 50 60 70 80 90 140 150 160 170 180 190 pF1KA0 CAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERARKLQETNLRV------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERARKLQETNLRVVSAPLP 100 110 120 130 140 150 pF1KA0 ------------------------------------------------------EGPQWL :::::: XP_016 RPGTSLELCRKALARQRARDLSETASALLAKDKQIAALQRECRELQARLTLVGKEGPQWL 160 170 180 190 200 210 200 210 220 230 240 250 pF1KA0 HVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPALQARAGAPAPGAPGEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPALQARAGAPAPGAPGEAT 220 230 240 250 260 270 260 270 280 290 300 310 pF1KA0 PQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARKKQRRCEELELQLRQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARKKQRRCEELELQLRQAQ 280 290 300 310 320 330 320 330 340 350 360 370 pF1KA0 NENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSALRKSQGLQSKLESLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSALRKSQGLQSKLESLEQ 340 350 360 370 380 390 380 390 400 410 420 430 pF1KA0 VLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQREHEGAVQLLESTLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQREHEGAVQLLESTLDS 400 410 420 430 440 450 440 450 460 470 480 490 pF1KA0 MQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALDCGSLGDCPPPPCCCSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALDCGSLGDCPPPPCCCSI 460 470 480 490 500 510 500 510 520 530 540 550 pF1KA0 PQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKKAESLSNSSHSESIHNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKKAESLSNSSHSESIHNS 520 530 540 550 560 570 560 570 580 590 600 610 pF1KA0 PKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLARYSYNPFEGPNENPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLARYSYNPFEGPNENPEA 580 590 600 610 620 630 620 630 640 650 660 670 pF1KA0 ELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSDDDLLTSLPPELADLSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSDDDLLTSLPPELADLSH 640 650 660 670 680 690 680 690 700 710 720 730 pF1KA0 SSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSPSPEGLGEPPAVPYPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSPSPEGLGEPPAVPYPRR 700 710 720 730 740 750 740 750 760 770 780 790 pF1KA0 LVVLKQLAHSVVLAWEPPPERVELHGFHICVNGELRQALGPGAPPKAVLENLDLRAGPLH ::::::::::::::::::::.::::::::::::::::::::::::::::::::: ::::: XP_016 LVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAPPKAVLENLDLWAGPLH 760 770 780 790 800 810 800 810 820 830 840 850 pF1KA0 ISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEITWVPGNSNLAHAIYLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEITWVPGNSNLAHAIYLN 820 830 840 850 860 870 860 870 880 890 900 910 pF1KA0 GEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWERLEQRAATLQFTTLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWERLEQRAATLQFTTLPA 880 890 900 910 920 930 920 930 940 950 960 970 pF1KA0 GPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYAIYADGQKIMEVASPTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYAIYADGQKIMEVASPTA 940 950 960 970 980 990 980 990 1000 1010 1020 1030 pF1KA0 GSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAPASLPARVSCPSPHPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAPASLPARVSCPSPHPSP 1000 1010 1020 1030 1040 1050 1040 1050 1060 1070 1080 1090 pF1KA0 EARAPLASASPGPGDPSSPLQLPAPLGTQEPPGAPPASPSREMPKGSHEDPPAPCSQEEA ::::::::::::::::::::: ::::::::::::::::::::: :::::::::::::::: XP_016 EARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMAKGSHEDPPAPCSQEEA 1060 1070 1080 1090 1100 1110 1100 1110 1120 1130 1140 1150 pF1KA0 GAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACPASSSTQGARAQQAPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACPASSSTQGARAQQAPNT 1120 1130 1140 1150 1160 1170 1160 1170 1180 1190 1200 1210 pF1KA0 EMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDIQEEEEEEEEEEEEELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDIQEEEEEEEEEEEEELG 1180 1190 1200 1210 1220 1230 1220 1230 1240 1250 1260 1270 pF1KA0 SRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELPLQQFCSKKLFSIPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELPLQQFCSKKLFSIPEEE 1240 1250 1260 1270 1280 1290 1280 1290 1300 1310 1320 1330 pF1KA0 EEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQCPLSPESSRAGDCLEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQCPLSPESSRAGDCLEDM 1300 1310 1320 1330 1340 1350 1340 1350 1360 1370 1380 1390 pF1KA0 PGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQASGRLGPTRERGGLPVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQASGRLGPTRERGGLPVIE 1360 1370 1380 1390 1400 1410 1400 1410 1420 1430 1440 1450 pF1KA0 GPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIEYDSEDEQEAGSGGISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIEYDSEDEQEAGSGGISI 1420 1430 1440 1450 1460 1470 1460 1470 1480 1490 1500 1510 pF1KA0 TSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEPERRGRSATGRAKEPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEPERRGRSATGRAKEPLS 1480 1490 1500 1510 1520 1530 1520 1530 1540 1550 1560 1570 pF1KA0 RATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETLAYQHLPVRIFVALFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETLAYQHLPVRIFVALFDY 1540 1550 1560 1570 1580 1590 1580 1590 1600 1610 1620 1630 pF1KA0 DPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRTGYIPCNMVAEVAVDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRTGYIPCNMVAEVAVDSP 1600 1610 1620 1630 1640 1650 1640 1650 1660 1670 1680 1690 pF1KA0 AGRQQLLQRGYLSPDILLEGSGNGPFVYSTARTTGPPPKPRRSKKAESEGPAQPCPGPPK :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: XP_016 AGRQQLLQRGYLSPDILLEGSGNGPFVYSTAHTTGPPPKPRRSKKAESEGPAQPCPGPPK 1660 1670 1680 1690 1700 1710 1700 1710 1720 1730 1740 1750 pF1KA0 LVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITVFGGMDDDGFYYGELNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITVFGGMDDDGFYYGELNG 1720 1730 1740 1750 1760 1770 1760 1770 1780 1790 pF1KA0 QRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC :::::::::::::::::::::::::::::::: XP_016 QRGLVPSNFLEGPGPEAGGLDREPRTPQAESQDWGCTTQGSPGPPGGPCTPSSGSAPRIE 1780 1790 1800 1810 1820 1830 XP_016 RGEPQGRSEKVWGFFSKGKQLLRRLGSGKKE 1840 1850 1860 >>XP_006722236 (OMIM: 610764) PREDICTED: peripheral-type (1907 aa) initn: 12155 init1: 10897 opt: 10917 Z-score: 4799.0 bits: 901.3 E(85289): 0 Smith-Waterman score: 11820; 96.4% identity (96.5% similar) in 1820 aa overlap (29-1788:29-1848) 10 20 30 40 50 60 pF1KA0 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES :::::::::::::::::::::::::::::::: XP_006 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA 130 140 150 160 170 180 190 pF1KA0 RKLQETNLRV-------------------------------------------------- :::::::::: XP_006 RKLQETNLRVVSAPLPRPGTSLELCRKALARQRARDLSETASALLAKDKQIAALQRECRE 190 200 210 220 230 240 200 210 220 230 240 pF1KA0 ----------EGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL :::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQARLTLVGKEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA0 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA0 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA0 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA0 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA0 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA0 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA0 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA0 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA0 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPERVELHGFHICVNGELRQALGPGAP ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: XP_006 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAP 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA0 PKAVLENLDLRAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PKAVLENLDLWAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA0 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA0 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA0 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA0 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQLPAPLGTQEPPGAPPASPSREMP ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_006 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMA 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 1140 pF1KA0 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP 1150 1160 1170 1180 1190 1200 1150 1160 1170 1180 1190 1200 pF1KA0 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI 1210 1220 1230 1240 1250 1260 1210 1220 1230 1240 1250 1260 pF1KA0 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP 1270 1280 1290 1300 1310 1320 1270 1280 1290 1300 1310 1320 pF1KA0 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC 1330 1340 1350 1360 1370 1380 1330 1340 1350 1360 1370 1380 pF1KA0 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS 1390 1400 1410 1420 1430 1440 1390 1400 1410 1420 1430 1440 pF1KA0 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE 1450 1460 1470 1480 1490 1500 1450 1460 1470 1480 1490 1500 pF1KA0 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP 1510 1520 1530 1540 1550 1560 1510 1520 1530 1540 1550 1560 pF1KA0 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL 1570 1580 1590 1600 1610 1620 1570 1580 1590 1600 1610 1620 pF1KA0 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT 1630 1640 1650 1660 1670 1680 1630 1640 1650 1660 1670 1680 pF1KA0 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTARTTGPPPKPRRSK :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: XP_006 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTAHTTGPPPKPRRSK 1690 1700 1710 1720 1730 1740 1690 1700 1710 1720 1730 1740 pF1KA0 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV 1750 1760 1770 1780 1790 1800 1750 1760 1770 1780 1790 pF1KA0 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC :::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQDWGCTTQGSPGP 1810 1820 1830 1840 1850 1860 XP_006 PGGPCTPSSGSAPRIERGEPQGRSEKVWGFFSKGKQLLRRLGSGKKE 1870 1880 1890 1900 >>XP_006722237 (OMIM: 610764) PREDICTED: peripheral-type (1900 aa) initn: 10550 init1: 9292 opt: 10851 Z-score: 4770.1 bits: 895.9 E(85289): 0 Smith-Waterman score: 11819; 96.1% identity (96.2% similar) in 1827 aa overlap (22-1788:22-1841) 10 20 30 40 50 60 pF1KA0 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES ::::::::::::::::::::::::::::::::::::::: XP_006 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA 130 140 150 160 170 180 190 pF1KA0 RKLQETNLRV-------------------------------------------------- :::::::::: XP_006 RKLQETNLRVVSAPLPRPGTSLELCRKALARQRARDLSETASALLAKDKQIAALQRECRE 190 200 210 220 230 240 200 210 220 230 240 pF1KA0 ----------EGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL :::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQARLTLVGKEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA0 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA0 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA0 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA0 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD ::::::::::: :::::::::::::::::::::::::::::::::::::::::: XP_006 REHEGAVQLLE-------ARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD 490 500 510 520 530 490 500 510 520 530 540 pF1KA0 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK 540 550 560 570 580 590 550 560 570 580 590 600 pF1KA0 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA 600 610 620 630 640 650 610 620 630 640 650 660 pF1KA0 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD 660 670 680 690 700 710 670 680 690 700 710 720 pF1KA0 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP 720 730 740 750 760 770 730 740 750 760 770 780 pF1KA0 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPERVELHGFHICVNGELRQALGPGAP ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: XP_006 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAP 780 790 800 810 820 830 790 800 810 820 830 840 pF1KA0 PKAVLENLDLRAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PKAVLENLDLWAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI 840 850 860 870 880 890 850 860 870 880 890 900 pF1KA0 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE 900 910 920 930 940 950 910 920 930 940 950 960 pF1KA0 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA 960 970 980 990 1000 1010 970 980 990 1000 1010 1020 pF1KA0 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP 1020 1030 1040 1050 1060 1070 1030 1040 1050 1060 1070 1080 pF1KA0 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQLPAPLGTQEPPGAPPASPSREMP ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_006 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMA 1080 1090 1100 1110 1120 1130 1090 1100 1110 1120 1130 1140 pF1KA0 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP 1140 1150 1160 1170 1180 1190 1150 1160 1170 1180 1190 1200 pF1KA0 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI 1200 1210 1220 1230 1240 1250 1210 1220 1230 1240 1250 1260 pF1KA0 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP 1260 1270 1280 1290 1300 1310 1270 1280 1290 1300 1310 1320 pF1KA0 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC 1320 1330 1340 1350 1360 1370 1330 1340 1350 1360 1370 1380 pF1KA0 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS 1380 1390 1400 1410 1420 1430 1390 1400 1410 1420 1430 1440 pF1KA0 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE 1440 1450 1460 1470 1480 1490 1450 1460 1470 1480 1490 1500 pF1KA0 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP 1500 1510 1520 1530 1540 1550 1510 1520 1530 1540 1550 1560 pF1KA0 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL 1560 1570 1580 1590 1600 1610 1570 1580 1590 1600 1610 1620 pF1KA0 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT 1620 1630 1640 1650 1660 1670 1630 1640 1650 1660 1670 1680 pF1KA0 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTARTTGPPPKPRRSK :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: XP_006 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTAHTTGPPPKPRRSK 1680 1690 1700 1710 1720 1730 1690 1700 1710 1720 1730 1740 pF1KA0 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV 1740 1750 1760 1770 1780 1790 1750 1760 1770 1780 1790 pF1KA0 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC :::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQDWGCTTQGSPGP 1800 1810 1820 1830 1840 1850 XP_006 PGGPCTPSSGSAPRIERGEPQGRSEKVWGFFSKGKQLLRRLGSGKKE 1860 1870 1880 1890 1900 >>NP_001248764 (OMIM: 610764) peripheral-type benzodiaze (1848 aa) initn: 11315 init1: 9980 opt: 10013 Z-score: 4403.0 bits: 827.9 E(85289): 0 Smith-Waterman score: 11793; 96.0% identity (96.1% similar) in 1829 aa overlap (29-1797:29-1848) 10 20 30 40 50 60 pF1KA0 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES :::::::::::::::::::::::::::::::: NP_001 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA 130 140 150 160 170 180 190 pF1KA0 RKLQETNLRV-------------------------------------------------- :::::::::: NP_001 RKLQETNLRVVSAPLPRPGTSLELCRKALARQRARDLSETASALLAKDKQIAALQRECRE 190 200 210 220 230 240 200 210 220 230 240 pF1KA0 ----------EGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQARLTLVGKEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA0 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA0 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA0 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA0 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA0 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA0 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA0 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA0 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA0 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPERVELHGFHICVNGELRQALGPGAP ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_001 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAP 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA0 PKAVLENLDLRAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKAVLENLDLWAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA0 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA0 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA0 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA0 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQLPAPLGTQEPPGAPPASPSREMP ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: NP_001 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMA 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 1140 pF1KA0 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP 1150 1160 1170 1180 1190 1200 1150 1160 1170 1180 1190 1200 pF1KA0 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI 1210 1220 1230 1240 1250 1260 1210 1220 1230 1240 1250 1260 pF1KA0 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP 1270 1280 1290 1300 1310 1320 1270 1280 1290 1300 1310 1320 pF1KA0 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC 1330 1340 1350 1360 1370 1380 1330 1340 1350 1360 1370 1380 pF1KA0 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS 1390 1400 1410 1420 1430 1440 1390 1400 1410 1420 1430 1440 pF1KA0 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE 1450 1460 1470 1480 1490 1500 1450 1460 1470 1480 1490 1500 pF1KA0 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP 1510 1520 1530 1540 1550 1560 1510 1520 1530 1540 1550 1560 pF1KA0 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL 1570 1580 1590 1600 1610 1620 1570 1580 1590 1600 1610 1620 pF1KA0 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT 1630 1640 1650 1660 1670 1680 1630 1640 1650 1660 1670 1680 pF1KA0 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTARTTGPPPKPRRSK ::::::::::::::::::::::::::::::::::::: :.:::::::::::: NP_001 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGS---------AHTTGPPPKPRRSK 1690 1700 1710 1720 1730 1690 1700 1710 1720 1730 1740 pF1KA0 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV 1740 1750 1760 1770 1780 1790 1750 1760 1770 1780 1790 pF1KA0 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC 1800 1810 1820 1830 1840 >>XP_005257864 (OMIM: 610764) PREDICTED: peripheral-type (1898 aa) initn: 11315 init1: 9980 opt: 10013 Z-score: 4402.9 bits: 828.0 E(85289): 0 Smith-Waterman score: 11728; 95.9% identity (96.0% similar) in 1820 aa overlap (29-1788:29-1839) 10 20 30 40 50 60 pF1KA0 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES :::::::::::::::::::::::::::::::: XP_005 MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA 130 140 150 160 170 180 190 pF1KA0 RKLQETNLRV-------------------------------------------------- :::::::::: XP_005 RKLQETNLRVVSAPLPRPGTSLELCRKALARQRARDLSETASALLAKDKQIAALQRECRE 190 200 210 220 230 240 200 210 220 230 240 pF1KA0 ----------EGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL :::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQARLTLVGKEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA0 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA0 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA0 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA0 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA0 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA0 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA0 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA0 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA0 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPERVELHGFHICVNGELRQALGPGAP ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: XP_005 SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAP 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA0 PKAVLENLDLRAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKAVLENLDLWAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA0 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA0 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA0 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA0 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQLPAPLGTQEPPGAPPASPSREMP ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_005 ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMA 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 1140 pF1KA0 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP 1150 1160 1170 1180 1190 1200 1150 1160 1170 1180 1190 1200 pF1KA0 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI 1210 1220 1230 1240 1250 1260 1210 1220 1230 1240 1250 1260 pF1KA0 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP 1270 1280 1290 1300 1310 1320 1270 1280 1290 1300 1310 1320 pF1KA0 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC 1330 1340 1350 1360 1370 1380 1330 1340 1350 1360 1370 1380 pF1KA0 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS 1390 1400 1410 1420 1430 1440 1390 1400 1410 1420 1430 1440 pF1KA0 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE 1450 1460 1470 1480 1490 1500 1450 1460 1470 1480 1490 1500 pF1KA0 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP 1510 1520 1530 1540 1550 1560 1510 1520 1530 1540 1550 1560 pF1KA0 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL 1570 1580 1590 1600 1610 1620 1570 1580 1590 1600 1610 1620 pF1KA0 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT 1630 1640 1650 1660 1670 1680 1630 1640 1650 1660 1670 1680 pF1KA0 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTARTTGPPPKPRRSK ::::::::::::::::::::::::::::::::::::: :.:::::::::::: XP_005 GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGS---------AHTTGPPPKPRRSK 1690 1700 1710 1720 1730 1690 1700 1710 1720 1730 1740 pF1KA0 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV 1740 1750 1760 1770 1780 1790 1750 1760 1770 1780 1790 pF1KA0 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQDWGCTTQGSPGP 1800 1810 1820 1830 1840 1850 XP_005 PGGPCTPSSGSAPRIERGEPQGRSEKVWGFFSKGKQLLRRLGSGKKE 1860 1870 1880 1890 1797 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:51:45 2016 done: Fri Nov 4 00:51:49 2016 Total Scan time: 23.750 Total Display time: 1.640 Function used was FASTA [36.3.4 Apr, 2011]