Result of FASTA (omim) for
pF1KA0621
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0621, 722 aa
1>>>pF1KA0621 722 - 722 aa - 722 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.3944+/-0.000577; mu= 5.6802+/- 0.035
mean_var=278.4579+/-62.303, 0's: 0 Z-trim(112.9): 412 B-trim: 34 in 1/53
Lambda= 0.076859
statistics sampled from 21524 (21976) to 21524 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.258), width: 16
Scan time: 10.150
The best scores are: opt bits E(85289)
XP_005268459 (OMIM: 605370,607785) PREDICTED: rho ( 722) 4709 537.2 8.7e-152
XP_005268457 (OMIM: 605370,607785) PREDICTED: rho ( 765) 4374 500.1 1.4e-140
NP_001129080 (OMIM: 605370,607785) rho GTPase-acti ( 759) 4316 493.6 1.2e-138
NP_055886 (OMIM: 605370,607785) rho GTPase-activat ( 814) 4316 493.7 1.2e-138
XP_005268456 (OMIM: 605370,607785) PREDICTED: rho ( 802) 3981 456.5 1.9e-127
XP_016864738 (OMIM: 605370,607785) PREDICTED: rho ( 811) 3981 456.5 1.9e-127
XP_016864737 (OMIM: 605370,607785) PREDICTED: rho ( 812) 3981 456.5 1.9e-127
XP_005268455 (OMIM: 605370,607785) PREDICTED: rho ( 857) 3981 456.5 1.9e-127
XP_016864736 (OMIM: 605370,607785) PREDICTED: rho ( 866) 3981 456.5 2e-127
XP_016864739 (OMIM: 605370,607785) PREDICTED: rho ( 725) 3972 455.5 3.5e-127
XP_006714837 (OMIM: 605370,607785) PREDICTED: rho ( 628) 3021 349.9 1.8e-95
XP_011535912 (OMIM: 605370,607785) PREDICTED: rho ( 616) 3015 349.3 2.8e-95
XP_011535913 (OMIM: 605370,607785) PREDICTED: rho ( 612) 3013 349.0 3.2e-95
XP_005263272 (OMIM: 609746) PREDICTED: rho GTPase- ( 735) 2559 298.8 5.2e-80
NP_078881 (OMIM: 609746) rho GTPase-activating pro ( 786) 2559 298.8 5.4e-80
NP_689645 (OMIM: 615936) rho GTPase-activating pro ( 874) 2394 280.6 1.9e-74
XP_006724716 (OMIM: 300127,300486) PREDICTED: olig ( 793) 2163 254.9 8.9e-67
XP_011529263 (OMIM: 300127,300486) PREDICTED: olig ( 802) 2163 254.9 9e-67
NP_002538 (OMIM: 300127,300486) oligophrenin-1 [Ho ( 802) 2163 254.9 9e-67
XP_005262327 (OMIM: 300127,300486) PREDICTED: olig ( 694) 2150 253.4 2.2e-66
XP_011540917 (OMIM: 615936) PREDICTED: rho GTPase- ( 820) 2142 252.6 4.6e-66
XP_016872726 (OMIM: 615936) PREDICTED: rho GTPase- ( 820) 2142 252.6 4.6e-66
XP_011540918 (OMIM: 615936) PREDICTED: rho GTPase- ( 820) 2142 252.6 4.6e-66
XP_016885044 (OMIM: 300127,300486) PREDICTED: olig ( 565) 2119 249.9 2.1e-65
XP_016864091 (OMIM: 609746) PREDICTED: rho GTPase- ( 694) 2018 238.8 5.7e-62
XP_016872727 (OMIM: 615936) PREDICTED: rho GTPase- ( 771) 1956 231.9 7.1e-60
XP_011540919 (OMIM: 615936) PREDICTED: rho GTPase- ( 780) 1949 231.2 1.2e-59
XP_011535914 (OMIM: 605370,607785) PREDICTED: rho ( 457) 1921 227.8 7.5e-59
XP_011509785 (OMIM: 610578) PREDICTED: rho GTPase- ( 397) 436 63.1 2.5e-09
XP_016859989 (OMIM: 610578) PREDICTED: rho GTPase- ( 432) 436 63.1 2.7e-09
XP_016859988 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 436 63.2 2.8e-09
XP_011509781 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 436 63.2 2.8e-09
NP_060930 (OMIM: 610578) rho GTPase-activating pro ( 475) 436 63.2 2.8e-09
NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778) 439 63.7 3.1e-09
XP_011510905 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 439 63.8 3.2e-09
NP_001280010 (OMIM: 602857) beta-chimaerin isoform ( 261) 423 61.4 5.3e-09
NP_001280002 (OMIM: 602857) beta-chimaerin isoform ( 287) 423 61.5 5.6e-09
NP_001035025 (OMIM: 602857) beta-chimaerin isoform ( 332) 423 61.5 6.1e-09
NP_001280000 (OMIM: 602857) beta-chimaerin isoform ( 433) 423 61.7 7.3e-09
NP_001280001 (OMIM: 602857) beta-chimaerin isoform ( 453) 423 61.7 7.5e-09
NP_004058 (OMIM: 602857) beta-chimaerin isoform 2 ( 468) 423 61.7 7.7e-09
NP_001279999 (OMIM: 602857) beta-chimaerin isoform ( 481) 423 61.7 7.8e-09
XP_011513409 (OMIM: 602857) PREDICTED: beta-chimae ( 494) 423 61.7 7.9e-09
XP_016867211 (OMIM: 602857) PREDICTED: beta-chimae ( 500) 423 61.7 8e-09
NP_001279998 (OMIM: 602857) beta-chimaerin isoform ( 543) 423 61.8 8.4e-09
XP_011513408 (OMIM: 602857) PREDICTED: beta-chimae ( 556) 423 61.8 8.6e-09
XP_011513407 (OMIM: 602857) PREDICTED: beta-chimae ( 569) 423 61.8 8.7e-09
XP_016867210 (OMIM: 602857) PREDICTED: beta-chimae ( 575) 423 61.8 8.7e-09
NP_001193531 (OMIM: 118423,604356) N-chimaerin iso ( 334) 412 60.3 1.4e-08
NP_001020372 (OMIM: 118423,604356) N-chimaerin iso ( 433) 412 60.4 1.7e-08
>>XP_005268459 (OMIM: 605370,607785) PREDICTED: rho GTPa (722 aa)
initn: 4709 init1: 4709 opt: 4709 Z-score: 2846.0 bits: 537.2 E(85289): 8.7e-152
Smith-Waterman score: 4709; 100.0% identity (100.0% similar) in 722 aa overlap (1-722:1-722)
10 20 30 40 50 60
pF1KA0 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 NSLTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSLTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVE
670 680 690 700 710 720
pF1KA0 FL
::
XP_005 FL
>>XP_005268457 (OMIM: 605370,607785) PREDICTED: rho GTPa (765 aa)
initn: 4374 init1: 4374 opt: 4374 Z-score: 2645.0 bits: 500.1 E(85289): 1.4e-140
Smith-Waterman score: 4374; 99.9% identity (100.0% similar) in 672 aa overlap (51-722:94-765)
30 40 50 60 70 80
pF1KA0 TLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLNEFKFQCIGDAETDDE
:.::::::::::::::::::::::::::::
XP_005 APLGAELLSLECPTVRMERALPRGRCLPLGKDLSSAKRKFADSLNEFKFQCIGDAETDDE
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLTPFRKAKALYACKAEHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLTPFRKAKALYACKAEHD
670 680 690 700 710 720
690 700 710 720
pF1KA0 SELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
::::::::::::::::::::::::::::::::::::::::::
XP_005 SELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
730 740 750 760
>>NP_001129080 (OMIM: 605370,607785) rho GTPase-activati (759 aa)
initn: 4704 init1: 4316 opt: 4316 Z-score: 2610.2 bits: 493.6 E(85289): 1.2e-138
Smith-Waterman score: 4593; 95.1% identity (95.1% similar) in 754 aa overlap (1-717:1-754)
10 20 30 40 50 60
pF1KA0 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP
610 620 630 640 650 660
670 680
pF1KA0 NSL-------------------------------------TPFRKAKALYACKAEHDSEL
::: ::::::::::::::::::::
NP_001 NSLPPNPSPTSPLSPSWPMFSAPSSPMPTSSTSSDSSPVSTPFRKAKALYACKAEHDSEL
670 680 690 700 710 720
690 700 710 720
pF1KA0 SFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
::::::::::::::::::::::::::::::::::
NP_001 SFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
730 740 750
>>NP_055886 (OMIM: 605370,607785) rho GTPase-activating (814 aa)
initn: 4316 init1: 4316 opt: 4316 Z-score: 2609.9 bits: 493.7 E(85289): 1.2e-138
Smith-Waterman score: 4316; 99.8% identity (99.8% similar) in 665 aa overlap (1-665:1-665)
10 20 30 40 50 60
pF1KA0 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 NSLTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVE
::: :
NP_055 NSLPPNPSPTSPLSPSWPMFSAPSSPMPTSSTSSDSSPVRSVAGFVWFSVAAVVLSLARS
670 680 690 700 710 720
>--
initn: 438 init1: 406 opt: 416 Z-score: 272.8 bits: 61.2 E(85289): 1.9e-08
Smith-Waterman score: 416; 67.3% identity (78.5% similar) in 107 aa overlap (618-722:716-814)
590 600 610 620 630 640
pF1KA0 SSDSKPPSCSERPLTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNS
:. :::..: : .: . .::..
NP_055 PMPTSSTSSDSSPVRSVAGFVWFSVAAVVLSLARSSLHAVFS----LLVNFVPCHPNLHL
690 700 710 720 730 740
650 660 670 680 690 700
pF1KA0 --SDPDLAVVKPTRPNSLTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEG
. :. :: . .: ::::::::::::::::::::::::::::::::::::::::::
NP_055 LFDRPEEAV----HEDSSTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEG
750 760 770 780 790
710 720
pF1KA0 TLNGKTGLIPENYVEFL
:::::::::::::::::
NP_055 TLNGKTGLIPENYVEFL
800 810
>>XP_005268456 (OMIM: 605370,607785) PREDICTED: rho GTPa (802 aa)
initn: 4361 init1: 3973 opt: 3981 Z-score: 2409.2 bits: 456.5 E(85289): 1.9e-127
Smith-Waterman score: 4258; 94.6% identity (94.7% similar) in 704 aa overlap (51-717:94-797)
30 40 50 60 70 80
pF1KA0 TLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLNEFKFQCIGDAETDDE
:.::::::::::::::::::::::::::::
XP_005 APLGAELLSLECPTVRMERALPRGRCLPLGKDLSSAKRKFADSLNEFKFQCIGDAETDDE
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
610 620 630 640 650 660
630 640 650 660
pF1KA0 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSL-----------------
:::::::::::::::::::::::::::::::::::::::::::
XP_005 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLPPNPSPTSPLSPSWPMF
670 680 690 700 710 720
670 680 690 700
pF1KA0 --------------------TPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWL
::::::::::::::::::::::::::::::::::::::::
XP_005 SAPSSPMPTSSTSSDSSPVSTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWL
730 740 750 760 770 780
710 720
pF1KA0 EGTLNGKTGLIPENYVEFL
::::::::::::::
XP_005 EGTLNGKTGLIPENYVEFL
790 800
>>XP_016864738 (OMIM: 605370,607785) PREDICTED: rho GTPa (811 aa)
initn: 3972 init1: 3972 opt: 3981 Z-score: 2409.2 bits: 456.5 E(85289): 1.9e-127
Smith-Waterman score: 3981; 94.9% identity (97.1% similar) in 652 aa overlap (51-701:94-745)
30 40 50 60 70 80
pF1KA0 TLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLNEFKFQCIGDAETDDE
:.::::::::::::::::::::::::::::
XP_016 APLGAELLSLECPTVRMERALPRGRCLPLGKDLSSAKRKFADSLNEFKFQCIGDAETDDE
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLTPFRKAKALYACKAEHD
:::::::::::::::::::::::::::::::::::::::::::. .:.. ..
XP_016 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLVHASSASSYHVYGMPGY
670 680 690 700 710 720
690 700 710 720
pF1KA0 S-ELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
: :. . . ..:::.. :
XP_016 CWEGSIPSPRIQAQLHPSRHLGPCSRRHPALCPPHPRPATHPPSAHRSGRQKPCMPAKLN
730 740 750 760 770 780
>>XP_016864737 (OMIM: 605370,607785) PREDICTED: rho GTPa (812 aa)
initn: 3973 init1: 3973 opt: 3981 Z-score: 2409.1 bits: 456.5 E(85289): 1.9e-127
Smith-Waterman score: 4171; 93.2% identity (93.3% similar) in 704 aa overlap (51-707:94-797)
30 40 50 60 70 80
pF1KA0 TLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLNEFKFQCIGDAETDDE
:.::::::::::::::::::::::::::::
XP_016 APLGAELLSLECPTVRMERALPRGRCLPLGKDLSSAKRKFADSLNEFKFQCIGDAETDDE
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
610 620 630 640 650 660
630 640 650 660
pF1KA0 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSL-----------------
:::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLPPNPSPTSPLSPSWPMF
670 680 690 700 710 720
670 680 690
pF1KA0 ------------------------------TPFRKAKALYACKAEHDSELSFTAGTVFDN
::::::::::::::::::::::::::::::
XP_016 SAPSSPMPTSSTSSDSSPVRPEEAVHEDSSTPFRKAKALYACKAEHDSELSFTAGTVFDN
730 740 750 760 770 780
700 710 720
pF1KA0 VHPSQEPGWLEGTLNGKTGLIPENYVEFL
::::::::::::::
XP_016 VHPSQEPGWLEGTLNGKTGLIPENYVEFL
790 800 810
>>XP_005268455 (OMIM: 605370,607785) PREDICTED: rho GTPa (857 aa)
initn: 3973 init1: 3973 opt: 3981 Z-score: 2408.9 bits: 456.5 E(85289): 1.9e-127
Smith-Waterman score: 3981; 99.7% identity (99.8% similar) in 615 aa overlap (51-665:94-708)
30 40 50 60 70 80
pF1KA0 TLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLNEFKFQCIGDAETDDE
:.::::::::::::::::::::::::::::
XP_005 APLGAELLSLECPTVRMERALPRGRCLPLGKDLSSAKRKFADSLNEFKFQCIGDAETDDE
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLTPFRKAKALYACKAEHD
::::::::::::::::::::::::::::::::::::::::::: :
XP_005 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLPPNPSPTSPLSPSWPMF
670 680 690 700 710 720
690 700 710 720
pF1KA0 SELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
XP_005 SAPSSPMPTSSTSSDSSPVRSVAGFVWFSVAAVVLSLARSSLHAVFSLLVNFVPCHPNLH
730 740 750 760 770 780
>--
initn: 438 init1: 406 opt: 416 Z-score: 272.5 bits: 61.2 E(85289): 1.9e-08
Smith-Waterman score: 416; 67.3% identity (78.5% similar) in 107 aa overlap (618-722:759-857)
590 600 610 620 630 640
pF1KA0 SSDSKPPSCSERPLTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNS
:. :::..: : .: . .::..
XP_005 PMPTSSTSSDSSPVRSVAGFVWFSVAAVVLSLARSSLHAVFS----LLVNFVPCHPNLHL
730 740 750 760 770 780
650 660 670 680 690 700
pF1KA0 --SDPDLAVVKPTRPNSLTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEG
. :. :: . .: ::::::::::::::::::::::::::::::::::::::::::
XP_005 LFDRPEEAV----HEDSSTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEG
790 800 810 820 830 840
710 720
pF1KA0 TLNGKTGLIPENYVEFL
:::::::::::::::::
XP_005 TLNGKTGLIPENYVEFL
850
>>XP_016864736 (OMIM: 605370,607785) PREDICTED: rho GTPa (866 aa)
initn: 3972 init1: 3972 opt: 3981 Z-score: 2408.8 bits: 456.5 E(85289): 2e-127
Smith-Waterman score: 3981; 94.9% identity (97.1% similar) in 652 aa overlap (51-701:94-745)
30 40 50 60 70 80
pF1KA0 TLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLNEFKFQCIGDAETDDE
:.::::::::::::::::::::::::::::
XP_016 APLGAELLSLECPTVRMERALPRGRCLPLGKDLSSAKRKFADSLNEFKFQCIGDAETDDE
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLTPFRKAKALYACKAEHD
:::::::::::::::::::::::::::::::::::::::::::. .:.. ..
XP_016 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLVHASSASSYHVYGMPGY
670 680 690 700 710 720
690 700 710 720
pF1KA0 S-ELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
: :. . . ..:::.. :
XP_016 CWEGSIPSPRIQAQLHPSRHLGPCSRRHPALCPPHPRPATHPPSGLLQGLFGFLLLPLFS
730 740 750 760 770 780
>>XP_016864739 (OMIM: 605370,607785) PREDICTED: rho GTPa (725 aa)
initn: 3972 init1: 3972 opt: 3972 Z-score: 2404.3 bits: 455.5 E(85289): 3.5e-127
Smith-Waterman score: 3972; 99.8% identity (100.0% similar) in 613 aa overlap (51-663:94-706)
30 40 50 60 70 80
pF1KA0 TLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLNEFKFQCIGDAETDDE
:.::::::::::::::::::::::::::::
XP_016 APLGAELLSLECPTVRMERALPRGRCLPLGKDLSSAKRKFADSLNEFKFQCIGDAETDDE
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILK
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSE
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDI
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEIL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSII
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLTPFRKAKALYACKAEHD
:::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLHWGFGMCLEGCTEVQSP
670 680 690 700 710 720
690 700 710 720
pF1KA0 SELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
XP_016 AS
722 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:52:31 2016 done: Fri Nov 4 00:52:33 2016
Total Scan time: 10.150 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]