FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0625, 2677 aa 1>>>pF1KA0625 2677 - 2677 aa - 2677 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2094+/-0.000483; mu= 13.7109+/- 0.030 mean_var=191.0745+/-38.992, 0's: 0 Z-trim(114.7): 39 B-trim: 37 in 1/54 Lambda= 0.092784 statistics sampled from 24736 (24768) to 24736 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.29), width: 16 Scan time: 24.000 The best scores are: opt bits E(85289) NP_055861 (OMIM: 602433,606002,608465) probable he (2677) 17830 2401.6 0 XP_016869984 (OMIM: 602433,606002,608465) PREDICTE (2677) 17830 2401.6 0 XP_005272230 (OMIM: 602433,606002,608465) PREDICTE (2706) 16119 2172.6 0 XP_005272228 (OMIM: 602433,606002,608465) PREDICTE (2706) 16119 2172.6 0 XP_011516706 (OMIM: 602433,606002,608465) PREDICTE (2706) 16119 2172.6 0 XP_005272229 (OMIM: 602433,606002,608465) PREDICTE (2706) 16119 2172.6 0 XP_011516707 (OMIM: 602433,606002,608465) PREDICTE (2706) 16119 2172.6 0 XP_011516708 (OMIM: 602433,606002,608465) PREDICTE (2413) 15942 2148.8 0 XP_011516709 (OMIM: 602433,606002,608465) PREDICTE (2372) 15721 2119.2 0 XP_011516710 (OMIM: 602433,606002,608465) PREDICTE (2191) 14478 1952.8 0 XP_016869986 (OMIM: 602433,606002,608465) PREDICTE ( 828) 5524 753.9 2.1e-216 XP_016869985 (OMIM: 602433,606002,608465) PREDICTE ( 857) 3813 524.9 1.9e-147 NP_002902 (OMIM: 601430) regulator of nonsense tra (1118) 450 74.8 7.7e-12 XP_016882595 (OMIM: 601430) PREDICTED: regulator o (1126) 450 74.8 7.7e-12 NP_001284478 (OMIM: 601430) regulator of nonsense (1129) 450 74.8 7.7e-12 XP_016882594 (OMIM: 601430) PREDICTED: regulator o (1137) 450 74.8 7.8e-12 NP_002171 (OMIM: 600502,604320,616155) DNA-binding ( 993) 385 66.1 2.9e-09 XP_005274031 (OMIM: 600502,604320,616155) PREDICTE ( 656) 365 63.3 1.4e-08 XP_016873159 (OMIM: 600502,604320,616155) PREDICTE ( 656) 365 63.3 1.4e-08 XP_016873158 (OMIM: 600502,604320,616155) PREDICTE ( 656) 365 63.3 1.4e-08 XP_005274032 (OMIM: 600502,604320,616155) PREDICTE ( 617) 288 52.9 1.6e-05 XP_011543296 (OMIM: 600502,604320,616155) PREDICTE ( 582) 285 52.5 2.1e-05 NP_055506 (OMIM: 610548) intron-binding protein aq (1485) 284 52.7 4.7e-05 XP_011537719 (OMIM: 601810,615156,615807) PREDICTE ( 700) 223 44.3 0.0075 XP_016871288 (OMIM: 601810,615156,615807) PREDICTE ( 836) 223 44.3 0.0086 >>NP_055861 (OMIM: 602433,606002,608465) probable helica (2677 aa) initn: 17830 init1: 17830 opt: 17830 Z-score: 12901.7 bits: 2401.6 E(85289): 0 Smith-Waterman score: 17830; 99.9% identity (100.0% similar) in 2677 aa overlap (1-2677:1-2677) 10 20 30 40 50 60 pF1KA0 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKGLIPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: NP_055 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SCRTTPAIVPPKKFRECPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_055 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 2460 pF1KA0 FLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCDKNYRHDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCDKNYRHDAV 2410 2420 2430 2440 2450 2460 2470 2480 2490 2500 2510 2520 pF1KA0 KILKLKPVLQRSLTHPPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKEITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KILKLKPVLQRSLTHPPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKEITL 2470 2480 2490 2500 2510 2520 2530 2540 2550 2560 2570 2580 pF1KA0 TVTSKDPERPPVHDQLQDPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPTGEPGFPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TVTSKDPERPPVHDQLQDPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPTGEPGFPVV 2530 2540 2550 2560 2570 2580 2590 2600 2610 2620 2630 2640 pF1KA0 HQDLSHIQQPAAVVAALSSHKPPVRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HQDLSHIQQPAAVVAALSSHKPPVRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSE 2590 2600 2610 2620 2630 2640 2650 2660 2670 pF1KA0 GEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKLL ::::::::::::::::::::::::::::::::::::: NP_055 GEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKLL 2650 2660 2670 >>XP_016869984 (OMIM: 602433,606002,608465) PREDICTED: p (2677 aa) initn: 17830 init1: 17830 opt: 17830 Z-score: 12901.7 bits: 2401.6 E(85289): 0 Smith-Waterman score: 17830; 99.9% identity (100.0% similar) in 2677 aa overlap (1-2677:1-2677) 10 20 30 40 50 60 pF1KA0 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKGLIPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_016 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SCRTTPAIVPPKKFRECPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_016 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 2460 pF1KA0 FLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCDKNYRHDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCDKNYRHDAV 2410 2420 2430 2440 2450 2460 2470 2480 2490 2500 2510 2520 pF1KA0 KILKLKPVLQRSLTHPPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKEITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KILKLKPVLQRSLTHPPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKEITL 2470 2480 2490 2500 2510 2520 2530 2540 2550 2560 2570 2580 pF1KA0 TVTSKDPERPPVHDQLQDPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPTGEPGFPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVTSKDPERPPVHDQLQDPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPTGEPGFPVV 2530 2540 2550 2560 2570 2580 2590 2600 2610 2620 2630 2640 pF1KA0 HQDLSHIQQPAAVVAALSSHKPPVRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HQDLSHIQQPAAVVAALSSHKPPVRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSE 2590 2600 2610 2620 2630 2640 2650 2660 2670 pF1KA0 GEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKLL ::::::::::::::::::::::::::::::::::::: XP_016 GEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKLL 2650 2660 2670 >>XP_005272230 (OMIM: 602433,606002,608465) PREDICTED: p (2706 aa) initn: 16119 init1: 16119 opt: 16119 Z-score: 11663.8 bits: 2172.6 E(85289): 0 Smith-Waterman score: 17762; 98.9% identity (98.9% similar) in 2706 aa overlap (1-2677:1-2706) 10 20 30 40 50 60 pF1KA0 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKGLIPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_005 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SCRTTPAIVPPKKFRECPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_005 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG 2350 2360 2370 2380 2390 2400 2410 2420 2430 pF1KA0 FLASLQRLNVTITRAKYSLFILGHLRTLM-----------------------------EN ::::::::::::::::::::::::::::: :: XP_005 FLASLQRLNVTITRAKYSLFILGHLRTLMQLLPRSFCVHVNHSPFFSPEPKYLHWALKEN 2410 2420 2430 2440 2450 2460 2440 2450 2460 2470 2480 2490 pF1KA0 QHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLP 2470 2480 2490 2500 2510 2520 2500 2510 2520 2530 2540 2550 pF1KA0 SSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKG 2530 2540 2550 2560 2570 2580 2560 2570 2580 2590 2600 2610 pF1KA0 GIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAA 2590 2600 2610 2620 2630 2640 2620 2630 2640 2650 2660 2670 pF1KA0 SPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSS 2650 2660 2670 2680 2690 2700 pF1KA0 KKRKLL :::::: XP_005 KKRKLL >>XP_005272228 (OMIM: 602433,606002,608465) PREDICTED: p (2706 aa) initn: 16119 init1: 16119 opt: 16119 Z-score: 11663.8 bits: 2172.6 E(85289): 0 Smith-Waterman score: 17762; 98.9% identity (98.9% similar) in 2706 aa overlap (1-2677:1-2706) 10 20 30 40 50 60 pF1KA0 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKGLIPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_005 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SCRTTPAIVPPKKFRECPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_005 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG 2350 2360 2370 2380 2390 2400 2410 2420 2430 pF1KA0 FLASLQRLNVTITRAKYSLFILGHLRTLM-----------------------------EN ::::::::::::::::::::::::::::: :: XP_005 FLASLQRLNVTITRAKYSLFILGHLRTLMQLLPRSFCVHVNHSPFFSPEPKYLHWALKEN 2410 2420 2430 2440 2450 2460 2440 2450 2460 2470 2480 2490 pF1KA0 QHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLP 2470 2480 2490 2500 2510 2520 2500 2510 2520 2530 2540 2550 pF1KA0 SSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKG 2530 2540 2550 2560 2570 2580 2560 2570 2580 2590 2600 2610 pF1KA0 GIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAA 2590 2600 2610 2620 2630 2640 2620 2630 2640 2650 2660 2670 pF1KA0 SPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSS 2650 2660 2670 2680 2690 2700 pF1KA0 KKRKLL :::::: XP_005 KKRKLL >>XP_011516706 (OMIM: 602433,606002,608465) PREDICTED: p (2706 aa) initn: 16119 init1: 16119 opt: 16119 Z-score: 11663.8 bits: 2172.6 E(85289): 0 Smith-Waterman score: 17762; 98.9% identity (98.9% similar) in 2706 aa overlap (1-2677:1-2706) 10 20 30 40 50 60 pF1KA0 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKGLIPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SCRTTPAIVPPKKFRECPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_011 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG 2350 2360 2370 2380 2390 2400 2410 2420 2430 pF1KA0 FLASLQRLNVTITRAKYSLFILGHLRTLM-----------------------------EN ::::::::::::::::::::::::::::: :: XP_011 FLASLQRLNVTITRAKYSLFILGHLRTLMQLLPRSFCVHVNHSPFFSPEPKYLHWALKEN 2410 2420 2430 2440 2450 2460 2440 2450 2460 2470 2480 2490 pF1KA0 QHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLP 2470 2480 2490 2500 2510 2520 2500 2510 2520 2530 2540 2550 pF1KA0 SSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKG 2530 2540 2550 2560 2570 2580 2560 2570 2580 2590 2600 2610 pF1KA0 GIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAA 2590 2600 2610 2620 2630 2640 2620 2630 2640 2650 2660 2670 pF1KA0 SPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSS 2650 2660 2670 2680 2690 2700 pF1KA0 KKRKLL :::::: XP_011 KKRKLL >>XP_005272229 (OMIM: 602433,606002,608465) PREDICTED: p (2706 aa) initn: 16119 init1: 16119 opt: 16119 Z-score: 11663.8 bits: 2172.6 E(85289): 0 Smith-Waterman score: 17762; 98.9% identity (98.9% similar) in 2706 aa overlap (1-2677:1-2706) 10 20 30 40 50 60 pF1KA0 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKGLIPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_005 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SCRTTPAIVPPKKFRECPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_005 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG 2350 2360 2370 2380 2390 2400 2410 2420 2430 pF1KA0 FLASLQRLNVTITRAKYSLFILGHLRTLM-----------------------------EN ::::::::::::::::::::::::::::: :: XP_005 FLASLQRLNVTITRAKYSLFILGHLRTLMQLLPRSFCVHVNHSPFFSPEPKYLHWALKEN 2410 2420 2430 2440 2450 2460 2440 2450 2460 2470 2480 2490 pF1KA0 QHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLP 2470 2480 2490 2500 2510 2520 2500 2510 2520 2530 2540 2550 pF1KA0 SSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKG 2530 2540 2550 2560 2570 2580 2560 2570 2580 2590 2600 2610 pF1KA0 GIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAA 2590 2600 2610 2620 2630 2640 2620 2630 2640 2650 2660 2670 pF1KA0 SPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSS 2650 2660 2670 2680 2690 2700 pF1KA0 KKRKLL :::::: XP_005 KKRKLL >>XP_011516707 (OMIM: 602433,606002,608465) PREDICTED: p (2706 aa) initn: 16119 init1: 16119 opt: 16119 Z-score: 11663.8 bits: 2172.6 E(85289): 0 Smith-Waterman score: 17762; 98.9% identity (98.9% similar) in 2706 aa overlap (1-2677:1-2706) 10 20 30 40 50 60 pF1KA0 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKGLIPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SCRTTPAIVPPKKFRECPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_011 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG 2350 2360 2370 2380 2390 2400 2410 2420 2430 pF1KA0 FLASLQRLNVTITRAKYSLFILGHLRTLM-----------------------------EN ::::::::::::::::::::::::::::: :: XP_011 FLASLQRLNVTITRAKYSLFILGHLRTLMQLLPRSFCVHVNHSPFFSPEPKYLHWALKEN 2410 2420 2430 2440 2450 2460 2440 2450 2460 2470 2480 2490 pF1KA0 QHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLP 2470 2480 2490 2500 2510 2520 2500 2510 2520 2530 2540 2550 pF1KA0 SSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKG 2530 2540 2550 2560 2570 2580 2560 2570 2580 2590 2600 2610 pF1KA0 GIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAA 2590 2600 2610 2620 2630 2640 2620 2630 2640 2650 2660 2670 pF1KA0 SPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSS 2650 2660 2670 2680 2690 2700 pF1KA0 KKRKLL :::::: XP_011 KKRKLL >>XP_011516708 (OMIM: 602433,606002,608465) PREDICTED: p (2413 aa) initn: 15942 init1: 15942 opt: 15942 Z-score: 11536.4 bits: 2148.8 E(85289): 0 Smith-Waterman score: 15942; 99.9% identity (100.0% similar) in 2400 aa overlap (1-2400:1-2400) 10 20 30 40 50 60 pF1KA0 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKGLIPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SCRTTPAIVPPKKFRECPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_011 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 2460 pF1KA0 FLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCDKNYRHDAV XP_011 NSSVPGTLYWDGE 2410 >>XP_011516709 (OMIM: 602433,606002,608465) PREDICTED: p (2372 aa) initn: 15721 init1: 15721 opt: 15721 Z-score: 11376.7 bits: 2119.2 E(85289): 0 Smith-Waterman score: 15721; 99.9% identity (100.0% similar) in 2367 aa overlap (1-2367:1-2367) 10 20 30 40 50 60 pF1KA0 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKGLIPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SCRTTPAIVPPKKFRECPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_011 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG ::::::::::::::::::::::::::: XP_011 NIGIITHYKAQKTMIQKDLDKEFDRKGSKIKD 2350 2360 2370 >>XP_011516710 (OMIM: 602433,606002,608465) PREDICTED: p (2191 aa) initn: 14478 init1: 14478 opt: 14478 Z-score: 10477.9 bits: 1952.8 E(85289): 0 Smith-Waterman score: 14478; 99.6% identity (99.8% similar) in 2190 aa overlap (1-2190:1-2190) 10 20 30 40 50 60 pF1KA0 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKGLIPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SCRTTPAIVPPKKFRECPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_011 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA ::::::::::::::::::::::... :. XP_011 LLLESAFRGQGGVPFSCVIVDEVSERSAIQL 2170 2180 2190 2677 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:29:22 2016 done: Wed Nov 2 19:29:25 2016 Total Scan time: 24.000 Total Display time: 1.850 Function used was FASTA [36.3.4 Apr, 2011]