FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0633, 1261 aa 1>>>pF1KA0633 1261 - 1261 aa - 1261 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.9615+/-0.000364; mu= -2.5027+/- 0.023 mean_var=296.9702+/-61.769, 0's: 0 Z-trim(122.6): 22 B-trim: 0 in 0/60 Lambda= 0.074425 statistics sampled from 40859 (40882) to 40859 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.479), width: 16 Scan time: 15.350 The best scores are: opt bits E(85289) NP_056013 (OMIM: 610317) protein cordon-bleu isofo (1261) 8440 920.6 0 NP_001333371 (OMIM: 610317) protein cordon-bleu is (1214) 7866 858.9 0 NP_001333372 (OMIM: 610317) protein cordon-bleu is (1173) 7856 857.9 0 XP_016867387 (OMIM: 610317) PREDICTED: protein cor (1276) 6938 759.3 3.6e-218 XP_011513539 (OMIM: 610317) PREDICTED: protein cor (1301) 6727 736.7 2.4e-211 XP_011513542 (OMIM: 610317) PREDICTED: protein cor (1239) 6153 675.0 8.4e-193 XP_011513541 (OMIM: 610317) PREDICTED: protein cor (1254) 6153 675.0 8.5e-193 XP_011513543 (OMIM: 610317) PREDICTED: protein cor (1047) 6069 666.0 3.8e-190 XP_005271808 (OMIM: 610317) PREDICTED: protein cor (1318) 6069 666.0 4.6e-190 XP_005271807 (OMIM: 610317) PREDICTED: protein cor (1333) 6069 666.0 4.6e-190 XP_011513537 (OMIM: 610317) PREDICTED: protein cor (1343) 6069 666.0 4.7e-190 XP_011513536 (OMIM: 610317) PREDICTED: protein cor (1358) 6069 666.0 4.7e-190 NP_001274365 (OMIM: 610317) protein cordon-bleu is (1271) 5495 604.4 1.6e-171 XP_011513538 (OMIM: 610317) PREDICTED: protein cor (1311) 5495 604.4 1.6e-171 NP_001333370 (OMIM: 610317) protein cordon-bleu is (1230) 5485 603.3 3.3e-171 XP_011513540 (OMIM: 610317) PREDICTED: protein cor (1270) 5485 603.3 3.3e-171 NP_001274367 (OMIM: 610317) protein cordon-bleu is ( 379) 2430 275.0 6.9e-73 NP_001333373 (OMIM: 610317) protein cordon-bleu is ( 469) 2430 275.0 8.2e-73 NP_001265390 (OMIM: 610318) cordon-bleu protein-li (1128) 712 90.8 5.7e-17 NP_055715 (OMIM: 610318) cordon-bleu protein-like (1166) 712 90.8 5.9e-17 NP_001265389 (OMIM: 610318) cordon-bleu protein-li (1174) 712 90.8 5.9e-17 NP_001265387 (OMIM: 610318) cordon-bleu protein-li (1233) 603 79.1 2e-13 >>NP_056013 (OMIM: 610317) protein cordon-bleu isoform b (1261 aa) initn: 8440 init1: 8440 opt: 8440 Z-score: 4909.4 bits: 920.6 E(85289): 0 Smith-Waterman score: 8440; 100.0% identity (100.0% similar) in 1261 aa overlap (1-1261:1-1261) 10 20 30 40 50 60 pF1KA0 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEEN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 RKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 SQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 EDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 VTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 HPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCY 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 DRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 GRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 MGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 LSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 PPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNET 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 DSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 LSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLL 1210 1220 1230 1240 1250 1260 pF1KA0 V : NP_056 V >>NP_001333371 (OMIM: 610317) protein cordon-bleu isofor (1214 aa) initn: 7935 init1: 7855 opt: 7866 Z-score: 4576.6 bits: 858.9 E(85289): 0 Smith-Waterman score: 8024; 96.3% identity (96.3% similar) in 1261 aa overlap (1-1261:1-1214) 10 20 30 40 50 60 pF1KA0 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEEN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 RKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 SQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 EDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 VTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 HPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCY 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 DRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 GRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 MGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 LSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 PPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNET 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 DSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGL :::::::::::::::::::::::::::: NP_001 LSYTEAEGERSALLAAIRGHSGTCSLRK-------------------------------- 1150 1160 1210 1220 1230 1240 1250 1260 pF1KA0 LSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLL ::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---------------ALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLL 1170 1180 1190 1200 1210 pF1KA0 V : NP_001 V >>NP_001333372 (OMIM: 610317) protein cordon-bleu isofor (1173 aa) initn: 7856 init1: 7856 opt: 7856 Z-score: 4571.0 bits: 857.9 E(85289): 0 Smith-Waterman score: 7856; 100.0% identity (100.0% similar) in 1169 aa overlap (1-1169:1-1169) 10 20 30 40 50 60 pF1KA0 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEEN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 RKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 SQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 EDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 VTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 HPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCY 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 DRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 GRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 MGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 LSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 PPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNET 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 DSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGL ::::::::::::::::::::::::::::: NP_001 LSYTEAEGERSALLAAIRGHSGTCSLRKVPLLV 1150 1160 1170 >>XP_016867387 (OMIM: 610317) PREDICTED: protein cordon- (1276 aa) initn: 6938 init1: 6938 opt: 6938 Z-score: 4037.7 bits: 759.3 E(85289): 3.6e-218 Smith-Waterman score: 8400; 98.8% identity (98.8% similar) in 1276 aa overlap (1-1261:1-1276) 10 20 30 40 50 60 pF1KA0 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 130 140 150 160 170 180 190 200 210 220 pF1KA0 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRR------------ :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRVRLSKTQSEPSL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 ---ETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCQETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 GSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPP 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 PSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTE 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 DSGVMSSPSDIVSLDSQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSGVMSSPSDIVSLDSQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSEN 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 SHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHC 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 PQDAMIPHGDTDAIPVTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQDAMIPHGDTDAIPVTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAE 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 HSQPHEKAREEVPALHPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSQPHEKAREEVPALHPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNA 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 KVKDKVYGCADGERTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVKDKVYGCADGERTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGL 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 TTYKIIPPKSEMRCYDRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTYKIIPPKSEMRCYDRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIG 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 KVREFWRCNSVEKHLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVREFWRCNSVEKHLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEG 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 RNPLGEGRNQPPTMGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNPLGEGRNQPPTMGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADV 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 VRPHGYAEKGYAGKAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRPHGYAEKGYAGKAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLA 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 VGAPPRGEVIGPHRKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGAPPRGEVIGPHRKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQE 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA0 ASSASEPRRAPDGTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASSASEPRRAPDGTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLE 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA0 REEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDR 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA0 LRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAAL 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA0 SAQGSESPLLEDLGLLSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAQGSESPLLEDLGLLSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAI 1210 1220 1230 1240 1250 1260 1250 1260 pF1KA0 RSGTGAARLRKVPLLV :::::::::::::::: XP_016 RSGTGAARLRKVPLLV 1270 >>XP_011513539 (OMIM: 610317) PREDICTED: protein cordon- (1301 aa) initn: 8220 init1: 6727 opt: 6727 Z-score: 3915.2 bits: 736.7 E(85289): 2.4e-211 Smith-Waterman score: 8288; 96.9% identity (96.9% similar) in 1293 aa overlap (9-1261:9-1301) 10 20 30 40 50 60 pF1KA0 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 130 140 150 160 170 180 190 200 210 220 pF1KA0 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRR------------ :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRVRLSKTQSEPSL 190 200 210 220 230 240 230 240 250 260 pF1KA0 ---ETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSK------------------------ ::::::::::::::::::::::::::::::::: XP_011 SCQETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSKAEQLVLSGADSDEDTSRAAPGRGL 250 260 270 280 290 300 270 280 290 300 310 320 pF1KA0 -GCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKV 310 320 330 340 350 360 330 340 350 360 370 380 pF1KA0 SLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPDG 370 380 390 400 410 420 390 400 410 420 430 440 pF1KA0 APQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQDSMKYKDKWATDQEDCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQDSMKYKDKWATDQEDCS 430 440 450 460 470 480 450 460 470 480 490 500 pF1KA0 DQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDL 490 500 510 520 530 540 510 520 530 540 550 560 pF1KA0 EEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTFIGEVSDDPVDSGLFSNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTFIGEVSDDPVDSGLFSNR 550 560 570 580 590 600 570 580 590 600 610 620 pF1KA0 NNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPASHDVGKGIRVALSNISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPASHDVGKGIRVALSNISK 610 620 630 640 650 660 630 640 650 660 670 680 pF1KA0 DGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERTQATERVNSQPVNEKDSNDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERTQATERVNSQPVNEKDSNDKN 670 680 690 700 710 720 690 700 710 720 730 740 pF1KA0 AALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCYDRDVSLSTGAIKIDELGNLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCYDRDVSLSTGAIKIDELGNLV 730 740 750 760 770 780 750 760 770 780 790 800 pF1KA0 SPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHLGRPSESSARGPPSTPVPTQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHLGRPSESSARGPPSTPVPTQT 790 800 810 820 830 840 810 820 830 840 850 860 pF1KA0 QNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGHVRVPAAHTTEVTFLKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGHVRVPAAHTTEVTFLKPQ 850 860 870 880 890 900 870 880 890 900 910 920 pF1KA0 RRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAPVLAAPPVTVKDDRTSSPHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAPVLAAPPVTVKDDRTSSPHS 910 920 930 940 950 960 930 940 950 960 970 980 pF1KA0 ETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRKLSTQDRPAAIHRSSCFSLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRKLSTQDRPAAIHRSSCFSLVQ 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KA0 SSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTDPPPPHTSDTQACSRELVNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTDPPPPHTSDTQACSRELVNGS 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KA0 VRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQ 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KA0 RPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGH 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KA0 SGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGLLSPPAIPPPPPPPSQALSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGLLSPPAIPPPPPPPSQALSAP 1210 1220 1230 1240 1250 1260 1230 1240 1250 1260 pF1KA0 RTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLLV ::::::::::::::::::::::::::::::::::::::::: XP_011 RTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLLV 1270 1280 1290 1300 >>XP_011513542 (OMIM: 610317) PREDICTED: protein cordon- (1239 aa) initn: 7921 init1: 6142 opt: 6153 Z-score: 3582.4 bits: 675.0 E(85289): 8.4e-193 Smith-Waterman score: 7964; 94.4% identity (94.4% similar) in 1286 aa overlap (1-1261:1-1239) 10 20 30 40 50 60 pF1KA0 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE 190 200 210 220 230 240 250 260 270 pF1KA0 TDKEKKKFLGFFKVNKRSNSK-------------------------GCLTTPNSPSMHSR ::::::::::::::::::::: :::::::::::::: XP_011 TDKEKKKFLGFFKVNKRSNSKAEQLVLSGADSDEDTSRAAPGRGLNGCLTTPNSPSMHSR 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 SLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRA 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA0 PAPPPPQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAPPPPQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVG 370 380 390 400 410 420 400 410 420 430 440 450 pF1KA0 SCFASEDTTEDSGVMSSPSDIVSLDSQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCFASEDTTEDSGVMSSPSDIVSLDSQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KA0 PLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLT 490 500 510 520 530 540 520 530 540 550 560 570 pF1KA0 SSIHGASNHCPQDAMIPHGDTDAIPVTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSIHGASNHCPQDAMIPHGDTDAIPVTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASR 550 560 570 580 590 600 580 590 600 610 620 630 pF1KA0 RDSLAPLQAEHSQPHEKAREEVPALHPASHDVGKGIRVALSNISKDGNLMETAPRVTSFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDSLAPLQAEHSQPHEKAREEVPALHPASHDVGKGIRVALSNISKDGNLMETAPRVTSFA 610 620 630 640 650 660 640 650 660 670 680 690 pF1KA0 SNLHTDNLNAKVKDKVYGCADGERTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNLHTDNLNAKVKDKVYGCADGERTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNP 670 680 690 700 710 720 700 710 720 730 740 750 pF1KA0 GKSYRLKHGLTTYKIIPPKSEMRCYDRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKSYRLKHGLTTYKIIPPKSEMRCYDRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSS 730 740 750 760 770 780 760 770 780 790 800 810 pF1KA0 VPEAESQPIGKVREFWRCNSVEKHLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPEAESQPIGKVREFWRCNSVEKHLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPIS 790 800 810 820 830 840 820 830 840 850 860 870 pF1KA0 PQQKSAHHEGRNPLGEGRNQPPTMGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQQKSAHHEGRNPLGEGRNQPPTMGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKR 850 860 870 880 890 900 880 890 900 910 920 930 pF1KA0 IGAPKVHADVVRPHGYAEKGYAGKAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGAPKVHADVVRPHGYAEKGYAGKAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVT 910 920 930 940 950 960 940 950 960 970 980 990 pF1KA0 PPNNHGEDLAVGAPPRGEVIGPHRKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPNNHGEDLAVGAPPRGEVIGPHRKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGF 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KA0 SGKQSTSSQEASSASEPRRAPDGTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGKQSTSSQEASSASEPRRAPDGTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGG 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KA0 SGTESHILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGTESHILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALME 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KA0 AIHSAGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASE ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIHSAGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRK------- 1150 1160 1170 1180 1190 1180 1190 1200 1210 1220 1230 pF1KA0 ELQSFRDAALSAQGSESPLLEDLGLLSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTA :::::::::::::::::::: XP_011 ----------------------------------------ALSAPRTASRFSTGTLSNTA 1200 1210 1240 1250 1260 pF1KA0 DARQALMDAIRSGTGAARLRKVPLLV :::::::::::::::::::::::::: XP_011 DARQALMDAIRSGTGAARLRKVPLLV 1220 1230 >>XP_011513541 (OMIM: 610317) PREDICTED: protein cordon- (1254 aa) initn: 7715 init1: 6142 opt: 6153 Z-score: 3582.3 bits: 675.0 E(85289): 8.5e-193 Smith-Waterman score: 7872; 93.3% identity (93.3% similar) in 1293 aa overlap (9-1261:9-1254) 10 20 30 40 50 60 pF1KA0 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 130 140 150 160 170 180 190 200 210 220 pF1KA0 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRR------------ :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRVRLSKTQSEPSL 190 200 210 220 230 240 230 240 250 260 pF1KA0 ---ETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSK------------------------ ::::::::::::::::::::::::::::::::: XP_011 SCQETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSKAEQLVLSGADSDEDTSRAAPGRGL 250 260 270 280 290 300 270 280 290 300 310 320 pF1KA0 -GCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKV 310 320 330 340 350 360 330 340 350 360 370 380 pF1KA0 SLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPDG 370 380 390 400 410 420 390 400 410 420 430 440 pF1KA0 APQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQDSMKYKDKWATDQEDCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQDSMKYKDKWATDQEDCS 430 440 450 460 470 480 450 460 470 480 490 500 pF1KA0 DQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDL 490 500 510 520 530 540 510 520 530 540 550 560 pF1KA0 EEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTFIGEVSDDPVDSGLFSNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTFIGEVSDDPVDSGLFSNR 550 560 570 580 590 600 570 580 590 600 610 620 pF1KA0 NNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPASHDVGKGIRVALSNISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPASHDVGKGIRVALSNISK 610 620 630 640 650 660 630 640 650 660 670 680 pF1KA0 DGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERTQATERVNSQPVNEKDSNDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERTQATERVNSQPVNEKDSNDKN 670 680 690 700 710 720 690 700 710 720 730 740 pF1KA0 AALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCYDRDVSLSTGAIKIDELGNLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCYDRDVSLSTGAIKIDELGNLV 730 740 750 760 770 780 750 760 770 780 790 800 pF1KA0 SPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHLGRPSESSARGPPSTPVPTQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHLGRPSESSARGPPSTPVPTQT 790 800 810 820 830 840 810 820 830 840 850 860 pF1KA0 QNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGHVRVPAAHTTEVTFLKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGHVRVPAAHTTEVTFLKPQ 850 860 870 880 890 900 870 880 890 900 910 920 pF1KA0 RRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAPVLAAPPVTVKDDRTSSPHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAPVLAAPPVTVKDDRTSSPHS 910 920 930 940 950 960 930 940 950 960 970 980 pF1KA0 ETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRKLSTQDRPAAIHRSSCFSLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRKLSTQDRPAAIHRSSCFSLVQ 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KA0 SSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTDPPPPHTSDTQACSRELVNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTDPPPPHTSDTQACSRELVNGS 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KA0 VRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQ 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KA0 RPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGH 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KA0 SGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGLLSPPAIPPPPPPPSQALSAP :::::::: ::::: XP_011 SGTCSLRK-----------------------------------------------ALSAP 1210 1230 1240 1250 1260 pF1KA0 RTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLLV ::::::::::::::::::::::::::::::::::::::::: XP_011 RTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLLV 1220 1230 1240 1250 >>XP_011513543 (OMIM: 610317) PREDICTED: protein cordon- (1047 aa) initn: 6034 init1: 6034 opt: 6069 Z-score: 3534.7 bits: 666.0 E(85289): 3.8e-190 Smith-Waterman score: 6526; 94.5% identity (94.6% similar) in 1047 aa overlap (272-1261:1-1047) 250 260 270 280 290 300 pF1KA0 DKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRR :::::::::::::::::::::::::::::: XP_011 MHSRSLTLGPSLSLGSISGVSVKSEMKKRR 10 20 30 310 320 330 340 350 360 pF1KA0 APPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEENR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEENR 40 50 60 70 80 90 pF1KA0 KSTM-------------------------------------------------------- :::: XP_011 KSTMGGGRQVPQKPPRGTARGPPQLVLPPPPPYPPPDTDVVEPLSFPGEGAGSEASDPIP 100 110 120 130 140 150 370 380 390 400 410 420 pF1KA0 -VSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQD .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQD 160 170 180 190 200 210 430 440 450 460 470 480 pF1KA0 SMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLL 220 230 240 250 260 270 490 500 510 520 530 540 pF1KA0 IAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTFI 280 290 300 310 320 330 550 560 570 580 590 600 pF1KA0 GEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPAS 340 350 360 370 380 390 610 620 630 640 650 660 pF1KA0 HDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERTQATE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERTQATE 400 410 420 430 440 450 670 680 690 700 710 720 pF1KA0 RVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCYDRDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCYDRDV 460 470 480 490 500 510 730 740 750 760 770 780 pF1KA0 SLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHLGRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHLGRPS 520 530 540 550 560 570 790 800 810 820 830 840 pF1KA0 ESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGHV 580 590 600 610 620 630 850 860 870 880 890 900 pF1KA0 RVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAPVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAPVLA 640 650 660 670 680 690 910 920 930 940 950 960 pF1KA0 APPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRKLSTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRKLSTQ 700 710 720 730 740 750 970 980 990 1000 1010 1020 pF1KA0 DRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTDPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTDPPPP 760 770 780 790 800 810 1030 1040 1050 1060 1070 1080 pF1KA0 HTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNETDSIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNETDSIW 820 830 840 850 860 870 1090 1100 1110 1120 1130 1140 pF1KA0 PPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAKLSYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAKLSYT 880 890 900 910 920 930 1150 1160 1170 1180 1190 1200 pF1KA0 EAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGLLSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGLLSPP 940 950 960 970 980 990 1210 1220 1230 1240 1250 1260 pF1KA0 AIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLLV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLLV 1000 1010 1020 1030 1040 >>XP_005271808 (OMIM: 610317) PREDICTED: protein cordon- (1318 aa) initn: 6034 init1: 6034 opt: 6069 Z-score: 3533.3 bits: 666.0 E(85289): 4.6e-190 Smith-Waterman score: 8133; 95.5% identity (95.6% similar) in 1293 aa overlap (26-1261:26-1318) 10 20 30 40 50 60 pF1KA0 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA ::::::::::::::::::::::::::::::::::: XP_005 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEEN 310 320 330 340 350 360 pF1KA0 RKSTM------------------------------------------------------- ::::: XP_005 RKSTMGGGRQVPQKPPRGTARGPPQLVLPPPPPYPPPDTDVVEPLSFPGEGAGSEASDPI 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA0 --VSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQ .::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKLSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQ 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA0 DSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDL 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA0 LIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTF 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA0 IGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA0 SHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERTQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERTQAT 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA0 ERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCYDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCYDRD 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA0 VSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHLGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHLGRP 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA0 SESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGH 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA0 VRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAPVL 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA0 AAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRKLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRKLST 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA0 QDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTDPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTDPPP 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA0 PHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNETDSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNETDSI 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 1140 pF1KA0 WPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAKLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAKLSY 1150 1160 1170 1180 1190 1200 1150 1160 1170 1180 1190 1200 pF1KA0 TEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGLLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGLLSP 1210 1220 1230 1240 1250 1260 1210 1220 1230 1240 1250 1260 pF1KA0 PAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLLV 1270 1280 1290 1300 1310 >>XP_005271807 (OMIM: 610317) PREDICTED: protein cordon- (1333 aa) initn: 7594 init1: 6034 opt: 6069 Z-score: 3533.2 bits: 666.0 E(85289): 4.6e-190 Smith-Waterman score: 7988; 94.4% identity (94.4% similar) in 1293 aa overlap (41-1261:41-1333) 20 30 40 50 60 70 pF1KA0 PPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLP :::::::::::::::::::::::::::::: XP_005 PPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLP 20 30 40 50 60 70 80 90 100 110 120 130 pF1KA0 SGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVH 80 90 100 110 120 130 140 150 160 170 180 190 pF1KA0 TVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNILPVICAKCEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNILPVICAKCEV 140 150 160 170 180 190 200 210 220 230 pF1KA0 SPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRR---------------ETFRKSS :::::::::::::::::::::::::::::::::::::: ::::::: XP_005 SPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRVRLSKTQSEPSLSCQETFRKSS 200 210 220 230 240 250 240 250 260 270 280 290 pF1KA0 LGNDETDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGNDETDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKS 260 270 280 290 300 310 300 310 320 330 340 350 pF1KA0 EMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTE 320 330 340 350 360 370 360 pF1KA0 DKEENRKSTM-------------------------------------------------- :::::::::: XP_005 DKEENRKSTMGGGRQVPQKPPRGTARGPPQLVLPPPPPYPPPDTDVVEPLSFPGEGAGSE 380 390 400 410 420 430 370 380 390 400 410 pF1KA0 -------VSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVS .:::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASDPIPKLSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVS 440 450 460 470 480 490 420 430 440 450 460 470 pF1KA0 LDSQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDSQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASN 500 510 520 530 540 550 480 490 500 510 520 530 pF1KA0 DEEDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DEEDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDA 560 570 580 590 600 610 540 550 560 570 580 590 pF1KA0 IPVTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IPVTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVP 620 630 640 650 660 670 600 610 620 630 640 650 pF1KA0 ALHPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALHPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGE 680 690 700 710 720 730 660 670 680 690 700 710 pF1KA0 RTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMR 740 750 760 770 780 790 720 730 740 750 760 770 pF1KA0 CYDRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CYDRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEK 800 810 820 830 840 850 780 790 800 810 820 830 pF1KA0 HLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPT 860 870 880 890 900 910 840 850 860 870 880 890 pF1KA0 MGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAG 920 930 940 950 960 970 900 910 920 930 940 950 pF1KA0 KAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPH 980 990 1000 1010 1020 1030 960 970 980 990 1000 1010 pF1KA0 RKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDG 1040 1050 1060 1070 1080 1090 1020 1030 1040 1050 1060 1070 pF1KA0 TDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGN 1100 1110 1120 1130 1140 1150 1080 1090 1100 1110 1120 1130 pF1KA0 ETDSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETDSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRP 1160 1170 1180 1190 1200 1210 1140 1150 1160 1170 1180 1190 pF1KA0 AKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDL 1220 1230 1240 1250 1260 1270 1200 1210 1220 1230 1240 1250 pF1KA0 GLLSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLLSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVP 1280 1290 1300 1310 1320 1330 1260 pF1KA0 LLV ::: XP_005 LLV 1261 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:00:43 2016 done: Thu Nov 3 10:00:45 2016 Total Scan time: 15.350 Total Display time: 0.560 Function used was FASTA [36.3.4 Apr, 2011]