Result of FASTA (ccds) for
pF1KA0656
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0656, 907 aa
1>>>pF1KA0656 907 - 907 aa - 907 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.4967+/-0.00129; mu= -9.7756+/- 0.078
mean_var=466.2078+/-100.694, 0's: 0 Z-trim(114.2): 70 B-trim: 602 in 2/50
Lambda= 0.059400
statistics sampled from 14678 (14734) to 14678 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.453), width: 16
Scan time: 4.910
The best scores are: opt bits E(32554)
CCDS47455.1 SNAP91 gene_id:9892|Hs108|chr6 ( 907) 5910 521.6 2.5e-147
CCDS56438.1 SNAP91 gene_id:9892|Hs108|chr6 ( 877) 4024 360.0 1.1e-98
CCDS56437.1 SNAP91 gene_id:9892|Hs108|chr6 ( 600) 1744 164.5 5.5e-40
CCDS8272.1 PICALM gene_id:8301|Hs108|chr11 ( 652) 1634 155.1 4e-37
CCDS55784.1 PICALM gene_id:8301|Hs108|chr11 ( 645) 1622 154.0 8.1e-37
CCDS31653.1 PICALM gene_id:8301|Hs108|chr11 ( 610) 1621 153.9 8.2e-37
CCDS55783.1 PICALM gene_id:8301|Hs108|chr11 ( 551) 1335 129.4 1.8e-29
>>CCDS47455.1 SNAP91 gene_id:9892|Hs108|chr6 (907 aa)
initn: 5910 init1: 5910 opt: 5910 Z-score: 2758.4 bits: 521.6 E(32554): 2.5e-147
Smith-Waterman score: 5910; 100.0% identity (100.0% similar) in 907 aa overlap (1-907:1-907)
10 20 30 40 50 60
pF1KA0 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 SSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 SSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 QWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGF
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 GMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 GMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLAD
850 860 870 880 890 900
pF1KA0 LNIKDFL
:::::::
CCDS47 LNIKDFL
>>CCDS56438.1 SNAP91 gene_id:9892|Hs108|chr6 (877 aa)
initn: 3830 init1: 2072 opt: 4024 Z-score: 1885.2 bits: 360.0 E(32554): 1.1e-98
Smith-Waterman score: 5632; 96.6% identity (96.7% similar) in 907 aa overlap (1-907:1-877)
10 20 30 40 50 60
pF1KA0 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::. :::::
CCDS56 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNK--SGAPS
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA
::::::::::::::: :::::::::::::::::
CCDS56 ASPVPESSLTADLLS----------------------------DAFGSSASEPQPASQAA
600 610 620 630
670 680 690 700 710 720
pF1KA0 SSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 LGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 QWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 QWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGF
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 GMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLAD
820 830 840 850 860 870
pF1KA0 LNIKDFL
:::::::
CCDS56 LNIKDFL
>>CCDS56437.1 SNAP91 gene_id:9892|Hs108|chr6 (600 aa)
initn: 3301 init1: 1649 opt: 1744 Z-score: 831.4 bits: 164.5 E(32554): 5.5e-40
Smith-Waterman score: 3336; 66.0% identity (66.2% similar) in 907 aa overlap (1-907:1-600)
10 20 30 40 50 60
pF1KA0 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS
::::::::::::::: :::::::::::::::::::::::. :::::
CCDS56 LTRMTRVSEFLKVAE--------------APSSLMETLEQHLNTLEGKKPGNK--SGAPS
250 260 270 280
310 320 330 340 350 360
pF1KA0 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA
::::::::::::::::::::
CCDS56 AAAAAAPAPPPPAGGATAWG----------------------------------------
350 360
430 440 450 460 470 480
pF1KA0 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF
CCDS56 ------------------------------------------------------------
490 500 510 520 530 540
pF1KA0 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT
CCDS56 ------------------------------------------------------------
550 560 570 580 590 600
pF1KA0 AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG
CCDS56 ------------------------------------------------------------
610 620 630 640 650 660
pF1KA0 ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA
CCDS56 ------------------------------------------------------------
670 680 690 700 710 720
pF1KA0 SSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 -----------GFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG
370 380 390 400 410
730 740 750 760 770 780
pF1KA0 LGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL
420 430 440 450 460 470
790 800 810 820 830 840
pF1KA0 QWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 QWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGF
480 490 500 510 520 530
850 860 870 880 890 900
pF1KA0 GMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLAD
540 550 560 570 580 590
pF1KA0 LNIKDFL
:::::::
CCDS56 LNIKDFL
600
>>CCDS8272.1 PICALM gene_id:8301|Hs108|chr11 (652 aa)
initn: 1924 init1: 1599 opt: 1634 Z-score: 780.0 bits: 155.1 E(32554): 4e-37
Smith-Waterman score: 1815; 43.8% identity (60.9% similar) in 882 aa overlap (1-878:1-649)
10 20 30 40 50 60
pF1KA0 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA
::::.:::::.:::.:::::::...::::::::.::::::::::::: ::: ::::::.:
CCDS82 MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM
:.::::.::::::::::.:.:::::::.:::::::::::::::::::::::::: .::::
CCDS82 DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE
::::::::::::::: ::::.::::..::.::::::::: :::::..::.:.:.::::.
CCDS82 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF
:.:. :::::::::::::::::: :.::: ::.:.::::::.:.:::.:::..:.:::.:
CCDS82 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS
::::::.:::::::::::::.::::::.::::::...::::: .::::: ..
CCDS82 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDS-------
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG
. .: :::... :. :.: . :: .:
CCDS82 --TAASRATTLSNAVSSLASTGLSLTKVDEREKQAAL-----------------------
300 310 320
370 380 390 400 410 420
pF1KA0 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA
:. : :... .: .... .: .: ::: . .
CCDS82 ------------------------EEEQARLKAL-KEQRLKE-LAKKPHTSLTTAA-SPV
330 340 350 360
430 440 450 460 470 480
pF1KA0 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF
:.::. :. :. :.: .::.
CCDS82 STSAGGIMTAPAI----DIF---------------------STPS---------------
370 380
490 500 510 520 530 540
pF1KA0 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT
: .:. :. ::. .. : : : : : ::: : .:
CCDS82 --SSNSTSKLPN-DLLDLQQP-TFHPSVHPM-STASQVAST-------------------
390 400 410
550 560 570 580 590 600
pF1KA0 AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG
.:: : .: ... :: ::.. : : ..
CCDS82 -----------------------WGDPFSATVDAV----DDAIPSLNPFLT-------KS
420 430 440
610 620 630 640 650 660
pF1KA0 ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA
.. : . :...: :..: :: .:..
CCDS82 SGDV-HLSISSD---VSTF------TTRTPTH----------------------------
450 460
670 680 690 700 710
pF1KA0 SSSSASADLLAGFGGSFMAPSPSPVT-PAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFD
....:: .::::. : . :. .::..:: . :.. : . ::
CCDS82 -------EMFVGF-------TPSPVAQPHPSAGLNVDFESVFG---NKSTNVIVDSGGFD
470 480 490 500
720 730 740 750 760 770
pF1KA0 GLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGD
:: :: ::.: .: ::. .::: : ...:::::::.::::::: :. : :.:
CCDS82 ELGGLLKPTVASQNQNLPVAKLPPS------KLVSDDLDSSLANLVGNLGI-GNGTTKND
510 520 530 540 550 560
780 790 800 810 820 830
pF1KA0 LQWNA-GEKKLTGGANWQPKVAPAT-WSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPG
..:. ::::::::.::::::::.: :.:. . .::: . :.. :
CCDS82 VNWSQPGEKKLTGGSNWQPKVAPTTAWNAA--------------TMAPPVMAYPATTPTG
570 580 590 600
840 850 860 870 880 890
pF1KA0 A-GFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKD
:.:.:: ..:.: : ....::.:::: . : :.:.
CCDS82 MIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM
610 620 630 640 650
900
pF1KA0 PLADLNIKDFL
>>CCDS55784.1 PICALM gene_id:8301|Hs108|chr11 (645 aa)
initn: 1924 init1: 1599 opt: 1622 Z-score: 774.5 bits: 154.0 E(32554): 8.1e-37
Smith-Waterman score: 1793; 43.5% identity (60.3% similar) in 882 aa overlap (1-878:1-642)
10 20 30 40 50 60
pF1KA0 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA
::::.:::::.:::.:::::::...::::::::.::::::::::::: ::: ::::::.:
CCDS55 MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM
:.::::.::::::::::.:.:::::::.:::::::::::::::::::::::::: .::::
CCDS55 DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE
::::::::::::::: ::::.::::..::.::::::::: :::::..::.:.:.::::.
CCDS55 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF
:.:. :::::::::::::::::: :.::: ::.:.::::::.:.:::.:::..:.:::.:
CCDS55 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS
::::::.:::::::::::::.::::::.::::::...::::: .::::: ..
CCDS55 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDS-------
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG
. .: :::... :. :.: . :: .:
CCDS55 --TAASRATTLSNAVSSLASTGLSLTKVDEREKQAAL-----------------------
300 310 320
370 380 390 400 410 420
pF1KA0 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA
:. : :... .: .... .: .: ::: . .
CCDS55 ------------------------EEEQARLKAL-KEQRLKE-LAKKPHTSLTTAA-SPV
330 340 350 360
430 440 450 460 470 480
pF1KA0 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF
:.::. :. :. :.: .::.
CCDS55 STSAGGIMTAPAI----DIF---------------------STPS---------------
370 380
490 500 510 520 530 540
pF1KA0 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT
: .:. :. ::. .. : : : : : ::: : .:
CCDS55 --SSNSTSKLPN-DLLDLQQP-TFHPSVHPM-STASQVAST-------------------
390 400 410
550 560 570 580 590 600
pF1KA0 AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG
.:: . :: ::.. : : ..
CCDS55 -----------------------WGDAVD-----------DAIPSLNPFLT-------KS
420 430
610 620 630 640 650 660
pF1KA0 ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA
.. : . :...: :..: :: .:..
CCDS55 SGDV-HLSISSD---VSTF------TTRTPTH----------------------------
440 450
670 680 690 700 710
pF1KA0 SSSSASADLLAGFGGSFMAPSPSPVT-PAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFD
....:: .::::. : . :. .::..:: . :.. : . ::
CCDS55 -------EMFVGF-------TPSPVAQPHPSAGLNVDFESVFG---NKSTNVIVDSGGFD
460 470 480 490 500
720 730 740 750 760 770
pF1KA0 GLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGD
:: :: ::.: .: ::. .::: : ...:::::::.::::::: :. : :.:
CCDS55 ELGGLLKPTVASQNQNLPVAKLPPS------KLVSDDLDSSLANLVGNLGI-GNGTTKND
510 520 530 540 550
780 790 800 810 820 830
pF1KA0 LQWNA-GEKKLTGGANWQPKVAPAT-WSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPG
..:. ::::::::.::::::::.: :.:. . .::: . :.. :
CCDS55 VNWSQPGEKKLTGGSNWQPKVAPTTAWNAA--------------TMAPPVMAYPATTPTG
560 570 580 590 600
840 850 860 870 880 890
pF1KA0 A-GFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKD
:.:.:: ..:.: : ....::.:::: . : :.:.
CCDS55 MIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM
610 620 630 640
900
pF1KA0 PLADLNIKDFL
>>CCDS31653.1 PICALM gene_id:8301|Hs108|chr11 (610 aa)
initn: 2029 init1: 1599 opt: 1621 Z-score: 774.3 bits: 153.9 E(32554): 8.2e-37
Smith-Waterman score: 1718; 43.7% identity (57.3% similar) in 882 aa overlap (1-878:1-607)
10 20 30 40 50 60
pF1KA0 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA
::::.:::::.:::.:::::::...::::::::.::::::::::::: ::: ::::::.:
CCDS31 MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM
:.::::.::::::::::.:.:::::::.:::::::::::::::::::::::::: .::::
CCDS31 DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE
::::::::::::::: ::::.::::..::.::::::::: :::::..::.:.:.::::.
CCDS31 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF
:.:. :::::::::::::::::: :.::: ::.:.::::::.:.:::.:::..:.:::.:
CCDS31 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS
::::::.:::::::::::::.::::::.::::::...::::: .::::: ..
CCDS31 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDS-------
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG
. .: :::...
CCDS31 --TAASRATTLSN-----------------------------------------------
300
370 380 390 400 410 420
pF1KA0 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA
:.::.
CCDS31 -----------------------------AVSSL--------------------------
430 440 450 460 470 480
pF1KA0 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF
::: ..: : . : :: : :
CCDS31 ---ASTGLSLTKVDER-------------EKQAALEEEQA--------------------
310 320 330
490 500 510 520 530 540
pF1KA0 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT
. .: .: .: : :.::. .:: ::.
CCDS31 ---RLKALKEQRLKELA-KKPHTSL--------------TTAASPV--------------
340 350 360
550 560 570 580 590 600
pF1KA0 AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG
.:::. ::: :.::: :::
CCDS31 -------STSAGGIMTAP-AIDIF-----STP----------------------------
370 380
610 620 630 640 650 660
pF1KA0 ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA
.: :.: ::: :: .: :. . :::.:
CCDS31 SSSNSTSKLPNDLL-------------------------DLQQPTFHPSVHPMSTASQVA
390 400 410
670 680 690 700 710
pF1KA0 SSSSASADLLAGFGGSFMAPSPSPVT-PAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFD
:. .:: : .::::. : . :. .::..:: . :.. : . ::
CCDS31 ST----------WGG-F---TPSPVAQPHPSAGLNVDFESVFG---NKSTNVIVDSGGFD
420 430 440 450
720 730 740 750 760 770
pF1KA0 GLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGD
:: :: ::.: .: ::. .::: : ...:::::::.::::::: :. : :.:
CCDS31 ELGGLLKPTVASQNQNLPVAKLPPS------KLVSDDLDSSLANLVGNLGI-GNGTTKND
460 470 480 490 500 510
780 790 800 810 820 830
pF1KA0 LQWNA-GEKKLTGGANWQPKVAPAT-WSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPG
..:. ::::::::.::::::::.: :.: : ..: : . ::: . :.. :
CCDS31 VNWSQPGEKKLTGGSNWQPKVAPTTAWNA-----ATMNGMHFPQYA-PPVMAYPATTPTG
520 530 540 550 560
840 850 860 870 880 890
pF1KA0 A-GFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKD
:.:.:: ..:.: : ....::.:::: . : :.:.
CCDS31 MIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM
570 580 590 600 610
900
pF1KA0 PLADLNIKDFL
>>CCDS55783.1 PICALM gene_id:8301|Hs108|chr11 (551 aa)
initn: 1638 init1: 1313 opt: 1335 Z-score: 642.5 bits: 129.4 E(32554): 1.8e-29
Smith-Waterman score: 1412; 41.0% identity (54.6% similar) in 830 aa overlap (53-878:2-548)
30 40 50 60 70 80
pF1KA0 ARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMADTLFERATNSSWVVVFKALVTT
::::::.::.::::.::::::::::.:.::
CCDS55 MNVNIPQLADSLFERTTNSSWVVVFKSLITT
10 20 30
90 100 110 120 130 140
pF1KA0 HHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDMSTFIRRYSRYLNEKAFSYRQMA
:::::.:::::::::::::::::::::::::: .::::::::::::::::::: ::::.:
CCDS55 HHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQVA
40 50 60 70 80 90
150 160 170 180 190 200
pF1KA0 FDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLEFDVHPNELTNGVINAAFMLLFK
:::..::.::::::::: :::::..::.:.:.::::.:.:. :::::::::::::::::
CCDS55 FDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFK
100 110 120 130 140 150
210 220 230 240 250 260
pF1KA0 DLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRFLTRMTRVSEFLKVAEQVGIDKG
: :.::: ::.:.::::::.:.:::.:::..:.:::.:::::::.:::::::::::::.:
CCDS55 DAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRG
160 170 180 190 200 210
270 280 290 300 310 320
pF1KA0 DIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTI
:::::.::::::...::::: .::::: .. :. :. .:
CCDS55 DIPDLSQAPSSLLDALEQHLASLEGKK------------IKDSTAASRAT----------
220 230 240
330 340 350 360 370 380
pF1KA0 DTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDL
: : ::
CCDS55 ----------TLSNAV--------------------------------------------
250
390 400 410 420 430 440
pF1KA0 LGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGD
:. ::: ..: : .
CCDS55 --------------------------------------SSLASTGLSLTKVDER------
260 270
450 460 470 480 490 500
pF1KA0 AFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPE
: :: : : . .: .: .: : :.
CCDS55 -------EKQAALEEEQA-----------------------RLKALKEQRLKELA-KKPH
280 290 300
510 520 530 540 550 560
pF1KA0 TSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALD
::. .:: ::. .:::. ::: :.:
CCDS55 TSL--------------TTAASPV---------------------STSAGGIMTAP-AID
310 320
570 580 590 600 610 620
pF1KA0 IFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAP
:: ::: :... :. :. :::
CCDS55 IF-----STPS----------------SSNSTSKLPN------------DLL--------
330 340
630 640 650 660 670 680
pF1KA0 SPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSP
:: .: :. . :::.::. .:: : .:
CCDS55 -----------------DLQQPTFHPSVHPMSTASQVAST----------WGG-F---TP
350 360 370
690 700 710 720 730 740
pF1KA0 SPVT-PAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMV
:::. : . :. .::..:: . :.. : . :: :: :: ::.: .: ::. .
CCDS55 SPVAQPHPSAGLNVDFESVFG---NKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKL
380 390 400 410 420
750 760 770 780 790 800
pF1KA0 PPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNA-GEKKLTGGANWQPKVA
:: :: ...:::::::.::::::: :. : :.:..:. ::::::::.:::::::
CCDS55 PP------SKLVSDDLDSSLANLVGNLGI-GNGTTKNDVNWSQPGEKKLTGGSNWQPKVA
430 440 450 460 470 480
810 820 830 840 850
pF1KA0 PAT-WSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGA-GFGMPPAGTGMPMMPQQPVM
:.: :.:. . .::: . :.. : :.:.:: ..:.: : ..
CCDS55 PTTAWNAA--------------TMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLI
490 500 510 520
860 870 880 890 900
pF1KA0 FAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLADLNIKDFL
..::.:::: . : :.:.
CCDS55 YSQPVMRPPNPFGPVSGAQIQFM
530 540 550
907 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:54:45 2016 done: Fri Nov 4 00:54:46 2016
Total Scan time: 4.910 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]