FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0660, 482 aa 1>>>pF1KA0660 482 - 482 aa - 482 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.9003+/-0.000989; mu= -4.9451+/- 0.060 mean_var=348.0721+/-70.483, 0's: 0 Z-trim(115.9): 25 B-trim: 3 in 1/53 Lambda= 0.068745 statistics sampled from 16487 (16507) to 16487 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.507), width: 16 Scan time: 3.910 The best scores are: opt bits E(32554) CCDS3571.1 G3BP2 gene_id:9908|Hs108|chr4 ( 482) 3307 341.4 1.3e-93 CCDS3572.1 G3BP2 gene_id:9908|Hs108|chr4 ( 449) 1646 176.7 4.6e-44 CCDS4319.1 G3BP1 gene_id:10146|Hs108|chr5 ( 466) 1600 172.1 1.1e-42 >>CCDS3571.1 G3BP2 gene_id:9908|Hs108|chr4 (482 aa) initn: 3307 init1: 3307 opt: 3307 Z-score: 1794.4 bits: 341.4 E(32554): 1.3e-93 Smith-Waterman score: 3307; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482) 10 20 30 40 50 60 pF1KA0 MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 IHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 PNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEKNLEELEEKSTTPPPAEPVSLPQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 VTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEKNLEELEEKSTTPPPAEPVSLPQEP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVEAKPEVQSQPPRVREQRPRERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 PKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVEAKPEVQSQPPRVREQRPRERP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GFPPRGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 GFPPRGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 RINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 RINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 GDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRGTGQMEGRFTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 GDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRGTGQMEGRFTGQ 430 440 450 460 470 480 pF1KA0 RR :: CCDS35 RR >>CCDS3572.1 G3BP2 gene_id:9908|Hs108|chr4 (449 aa) initn: 1701 init1: 1643 opt: 1646 Z-score: 904.5 bits: 176.7 E(32554): 4.6e-44 Smith-Waterman score: 3011; 93.2% identity (93.2% similar) in 482 aa overlap (1-482:1-449) 10 20 30 40 50 60 pF1KA0 MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 IHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 PNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEKNLEELEEKSTTPPPAEPVSLPQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 VTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEKNLEELEEKSTTPPPAEPVSLPQEP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVEAKPEVQSQPPRVREQRPRERP :: ::::::::::::::::::::::::: CCDS35 PK---------------------------------PRVEAKPEVQSQPPRVREQRPRERP 250 260 310 320 330 340 350 360 pF1KA0 GFPPRGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 GFPPRGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVEL 270 280 290 300 310 320 370 380 390 400 410 420 pF1KA0 RINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 RINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGG 330 340 350 360 370 380 430 440 450 460 470 480 pF1KA0 GDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRGTGQMEGRFTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 GDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRGTGQMEGRFTGQ 390 400 410 420 430 440 pF1KA0 RR :: CCDS35 RR >>CCDS4319.1 G3BP1 gene_id:10146|Hs108|chr5 (466 aa) initn: 1595 init1: 860 opt: 1600 Z-score: 879.6 bits: 172.1 E(32554): 1.1e-42 Smith-Waterman score: 1981; 65.4% identity (80.3% similar) in 482 aa overlap (1-471:1-461) 10 20 30 40 50 60 pF1KA0 MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQND ::::::::::::::::::::::::.::..::::::.::::::::.:..::: .:::::.. CCDS43 MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSV ::.::.: ::..::::::::::::::.:::::::::::::..: :.::::::::::::: CCDS43 IHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHP ::::::::.:::.::::: : .::::.:::: :::: .:: : ..... .:. CCDS43 ANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEP-EERQQTPEVVPDDSGT-FYDQAV 130 140 150 160 170 190 200 210 220 230 pF1KA0 VTNGIEEPLEESSHEPEPEPESETKTE------ELKPQ-VEEKNLEELEEKSTTPPPAEP :.: .:: ::: ::::.:: : . : : ::. : :.. : .::..: ::. CCDS43 VSNDMEEHLEEPVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 VSLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHV-KAPVSQPRVEAKPEVQSQPPRV- .. :: ..:::::::::::::::.: .:::::: :.:.:::: :.::: : : : CCDS43 AQTVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQ 240 250 260 270 280 290 300 310 320 330 340 pF1KA0 REQRPRE-RPGFPP-RGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKE :.:: :: : ..:: ::::: : ::.: . ::..:.:::::::.:::::..:..:::. CCDS43 RDQRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKD 300 310 320 330 340 350 350 360 370 380 390 400 pF1KA0 FFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKT ::.:.:::::::::. :::::::::::::::::::..: .::::::::::::::::: CCDS43 FFQSYGNVVELRINS---GGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKT 360 370 380 390 400 410 410 420 430 440 450 460 pF1KA0 RAARERETRGGGDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRG ::::: :::: : :::::::: .:::: :::: ::::.:: : : : CCDS43 RAARE-------GDRRDNRL--RGPGGPRGGLGGGM------RGPP-RGGMVQKPGFGVG 420 430 440 450 470 480 pF1KA0 TGQMEGRFTGQRR : CCDS43 RGLAPRQ 460 482 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:30:08 2016 done: Wed Nov 2 19:30:09 2016 Total Scan time: 3.910 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]