Result of FASTA (omim) for
pF1KA0687
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0687, 1037 aa
1>>>pF1KA0687 1037 - 1037 aa - 1037 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.5944+/-0.000567; mu= -22.4709+/- 0.035
mean_var=726.5207+/-153.434, 0's: 0 Z-trim(119.3): 1335 B-trim: 0 in 0/58
Lambda= 0.047583
statistics sampled from 31208 (33150) to 31208 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.389), width: 16
Scan time: 14.920
The best scores are: opt bits E(85289)
XP_016860861 (OMIM: 604666) PREDICTED: mitogen-act (1166) 4377 317.3 3.1e-85
NP_004825 (OMIM: 604666) mitogen-activated protein (1165) 4360 316.2 6.8e-85
XP_016860862 (OMIM: 604666) PREDICTED: mitogen-act (1163) 4335 314.5 2.2e-84
XP_016860858 (OMIM: 604666) PREDICTED: mitogen-act (1196) 4314 313.0 6.2e-84
XP_016860863 (OMIM: 604666) PREDICTED: mitogen-act (1158) 4294 311.6 1.6e-83
XP_006712932 (OMIM: 604666) PREDICTED: mitogen-act (1189) 4248 308.5 1.4e-82
XP_016860859 (OMIM: 604666) PREDICTED: mitogen-act (1188) 4231 307.3 3.2e-82
XP_016860855 (OMIM: 604666) PREDICTED: mitogen-act (1243) 4152 301.9 1.4e-80
XP_016860848 (OMIM: 604666) PREDICTED: mitogen-act (1274) 4152 301.9 1.4e-80
XP_016860849 (OMIM: 604666) PREDICTED: mitogen-act (1273) 4135 300.8 3.3e-80
NP_663720 (OMIM: 604666) mitogen-activated protein (1212) 4078 296.8 4.7e-79
XP_016860854 (OMIM: 604666) PREDICTED: mitogen-act (1243) 4078 296.8 4.8e-79
NP_001229489 (OMIM: 604666) mitogen-activated prot (1235) 4069 296.2 7.4e-79
XP_016860850 (OMIM: 604666) PREDICTED: mitogen-act (1266) 4069 296.2 7.5e-79
XP_016860857 (OMIM: 604666) PREDICTED: mitogen-act (1211) 4061 295.7 1.1e-78
XP_016860856 (OMIM: 604666) PREDICTED: mitogen-act (1234) 4052 295.1 1.7e-78
XP_016860851 (OMIM: 604666) PREDICTED: mitogen-act (1265) 4052 295.1 1.7e-78
XP_005264125 (OMIM: 604666) PREDICTED: mitogen-act (1227) 2769 207.0 5.4e-52
XP_005264123 (OMIM: 604666) PREDICTED: mitogen-act (1229) 2768 206.9 5.6e-52
XP_005264122 (OMIM: 604666) PREDICTED: mitogen-act (1230) 2763 206.6 7.1e-52
XP_005264117 (OMIM: 604666) PREDICTED: mitogen-act (1280) 2759 206.3 8.9e-52
XP_016860840 (OMIM: 604666) PREDICTED: mitogen-act (1311) 2759 206.3 9e-52
XP_016860845 (OMIM: 604666) PREDICTED: mitogen-act (1281) 2758 206.2 9.3e-52
XP_005264115 (OMIM: 604666) PREDICTED: mitogen-act (1312) 2758 206.3 9.5e-52
XP_005264121 (OMIM: 604666) PREDICTED: mitogen-act (1258) 2753 205.9 1.2e-51
XP_005264120 (OMIM: 604666) PREDICTED: mitogen-act (1260) 2752 205.8 1.2e-51
XP_005264116 (OMIM: 604666) PREDICTED: mitogen-act (1284) 2752 205.8 1.2e-51
XP_005264114 (OMIM: 604666) PREDICTED: mitogen-act (1315) 2752 205.8 1.3e-51
XP_005264119 (OMIM: 604666) PREDICTED: mitogen-act (1261) 2750 205.7 1.3e-51
XP_006712928 (OMIM: 604666) PREDICTED: mitogen-act (1307) 2750 205.7 1.4e-51
XP_005264109 (OMIM: 604666) PREDICTED: mitogen-act (1337) 2750 205.7 1.4e-51
XP_005264107 (OMIM: 604666) PREDICTED: mitogen-act (1338) 2750 205.7 1.4e-51
XP_016860844 (OMIM: 604666) PREDICTED: mitogen-act (1296) 2613 196.3 9.3e-49
XP_016860843 (OMIM: 604666) PREDICTED: mitogen-act (1299) 2613 196.3 9.3e-49
XP_016860864 (OMIM: 604666) PREDICTED: mitogen-act (1155) 2597 195.1 1.8e-48
XP_005264128 (OMIM: 604666) PREDICTED: mitogen-act (1185) 2597 195.2 1.9e-48
XP_016860860 (OMIM: 604666) PREDICTED: mitogen-act (1186) 2597 195.2 1.9e-48
XP_005264126 (OMIM: 604666) PREDICTED: mitogen-act (1209) 2597 195.2 1.9e-48
XP_006712931 (OMIM: 604666) PREDICTED: mitogen-act (1222) 2597 195.2 1.9e-48
NP_001229488 (OMIM: 604666) mitogen-activated prot (1239) 2597 195.2 1.9e-48
XP_016860853 (OMIM: 604666) PREDICTED: mitogen-act (1249) 2597 195.2 1.9e-48
XP_016860852 (OMIM: 604666) PREDICTED: mitogen-act (1253) 2597 195.2 1.9e-48
NP_663719 (OMIM: 604666) mitogen-activated protein (1273) 2597 195.2 2e-48
XP_016860847 (OMIM: 604666) PREDICTED: mitogen-act (1275) 2597 195.2 2e-48
XP_016860846 (OMIM: 604666) PREDICTED: mitogen-act (1276) 2597 195.2 2e-48
XP_016860842 (OMIM: 604666) PREDICTED: mitogen-act (1306) 2597 195.2 2e-48
XP_016860841 (OMIM: 604666) PREDICTED: mitogen-act (1307) 2597 195.2 2e-48
XP_016860839 (OMIM: 604666) PREDICTED: mitogen-act (1330) 2597 195.2 2e-48
XP_016860838 (OMIM: 604666) PREDICTED: mitogen-act (1352) 2597 195.2 2.1e-48
XP_005264105 (OMIM: 604666) PREDICTED: mitogen-act (1384) 2597 195.2 2.1e-48
>>XP_016860861 (OMIM: 604666) PREDICTED: mitogen-activat (1166 aa)
initn: 4338 init1: 4338 opt: 4377 Z-score: 1651.3 bits: 317.3 E(85289): 3.1e-85
Smith-Waterman score: 6002; 87.9% identity (87.9% similar) in 1069 aa overlap (98-1037:98-1166)
70 80 90 100 110 120
pF1KA0 LEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKE
::::::::::::::::::::::::::::::
XP_016 LEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 NPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERS
310 320 330 340 350 360
370 380
pF1KA0 EALRRQQLLQEQQLREQE------------------------------------------
::::::::::::::::::
XP_016 EALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQ
370 380 390 400 410 420
pF1KA0 ------------------------------------------------------------
XP_016 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL
430 440 450 460 470 480
390 400 410
pF1KA0 ---------------------------RSKPSFHAPEPKAHYEPADRAREVPVRTTSRSP
:::::::::::::::::::::::::::::::::
XP_016 QEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVPVRTTSRSP
490 500 510 520 530 540
420 430 440 450 460 470
pF1KA0 VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG
550 560 570 580 590 600
480 490 500 510 520 530
pF1KA0 SHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKE
610 620 630 640 650 660
540 550 560 570 580 590
pF1KA0 LRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGE
670 680 690 700 710 720
600 610 620 630 640 650
pF1KA0 TESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQIS
730 740 750 760 770 780
660 670 680 690 700 710
pF1KA0 PSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSE
790 800 810 820 830 840
720 730 740 750 760 770
pF1KA0 ILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDK
850 860 870 880 890 900
780 790 800 810 820 830
pF1KA0 LRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVY
910 920 930 940 950 960
840 850 860 870 880 890
pF1KA0 AWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIY
970 980 990 1000 1010 1020
900 910 920 930 940 950
pF1KA0 LPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
1030 1040 1050 1060 1070 1080
960 970 980 990 1000 1010
pF1KA0 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
1090 1100 1110 1120 1130 1140
1020 1030
pF1KA0 GGSSQVYFMTLGRTSLLSW
:::::::::::::::::::
XP_016 GGSSQVYFMTLGRTSLLSW
1150 1160
>--
initn: 629 init1: 629 opt: 629 Z-score: 260.8 bits: 60.0 E(85289): 8.6e-08
Smith-Waterman score: 629; 100.0% identity (100.0% similar) in 97 aa overlap (1-97:1-97)
10 20 30 40 50 60
pF1KA0 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
:::::::::::::::::::::::::::::::::::::
XP_016 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
XP_016 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
>>NP_004825 (OMIM: 604666) mitogen-activated protein kin (1165 aa)
initn: 6508 init1: 3925 opt: 4360 Z-score: 1645.0 bits: 316.2 E(85289): 6.8e-85
Smith-Waterman score: 5995; 87.9% identity (87.9% similar) in 1070 aa overlap (97-1037:97-1165)
70 80 90 100 110 120
pF1KA0 KLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLK
::::::::::::::::::::::::::::::
NP_004 KLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 RNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKER
310 320 330 340 350 360
370 380
pF1KA0 SEALRRQQLLQEQQLREQE-----------------------------------------
:::::::::::::::::::
NP_004 SEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQERE
370 380 390 400 410 420
pF1KA0 ------------------------------------------------------------
NP_004 QRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQL
430 440 450 460 470 480
390 400 410
pF1KA0 ----------------------------RSKPSFHAPEPKAHYEPADRAREVPVRTTSRS
::::::::::::::::::::::::::::::::
NP_004 LQEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVPVRTTSRS
490 500 510 520 530 540
420 430 440 450 460 470
pF1KA0 PVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQP
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
NP_004 PVLSRRDSPLQGSGQQNSQAGQRNSTS-IEPRLLWERVEKLVPRPGSGSSSGSSNSGSQP
550 560 570 580 590 600
480 490 500 510 520 530
pF1KA0 GSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAK
610 620 630 640 650 660
540 550 560 570 580 590
pF1KA0 ELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNG
670 680 690 700 710 720
600 610 620 630 640 650
pF1KA0 ETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQI
730 740 750 760 770 780
660 670 680 690 700 710
pF1KA0 SPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNS
790 800 810 820 830 840
720 730 740 750 760 770
pF1KA0 EILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKD
850 860 870 880 890 900
780 790 800 810 820 830
pF1KA0 KLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEV
910 920 930 940 950 960
840 850 860 870 880 890
pF1KA0 YAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDI
970 980 990 1000 1010 1020
900 910 920 930 940 950
pF1KA0 YLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWG
1030 1040 1050 1060 1070 1080
960 970 980 990 1000 1010
pF1KA0 EMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVR
1090 1100 1110 1120 1130 1140
1020 1030
pF1KA0 SGGSSQVYFMTLGRTSLLSW
::::::::::::::::::::
NP_004 SGGSSQVYFMTLGRTSLLSW
1150 1160
>--
initn: 619 init1: 619 opt: 619 Z-score: 257.1 bits: 59.4 E(85289): 1.4e-07
Smith-Waterman score: 619; 100.0% identity (100.0% similar) in 96 aa overlap (1-96:1-96)
10 20 30 40 50 60
pF1KA0 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
::::::::::::::::::::::::::::::::::::
NP_004 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
NP_004 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
>>XP_016860862 (OMIM: 604666) PREDICTED: mitogen-activat (1163 aa)
initn: 5991 init1: 3344 opt: 4335 Z-score: 1635.8 bits: 314.5 E(85289): 2.2e-84
Smith-Waterman score: 5995; 87.7% identity (87.7% similar) in 1072 aa overlap (95-1037:95-1163)
70 80 90 100 110 120
pF1KA0 EIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNT
::::::::::::::::::::::::::::::
XP_016 EIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 RNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 IPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 HIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENK
310 320 330 340 350 360
370 380
pF1KA0 ERSEALRRQQLLQEQQLREQE---------------------------------------
:::::::::::::::::::::
XP_016 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE
370 380 390 400 410 420
pF1KA0 ------------------------------------------------------------
XP_016 REQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQ
430 440 450 460 470 480
390 400 410
pF1KA0 ------------------------------RSKPSFHAPEPKAHYEPADRAREVPVRTTS
::::::::::::::::::::::::::::::
XP_016 QLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVPVRTTS
490 500 510 520 530 540
420 430 440 450 460 470
pF1KA0 RSPVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSPVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGS
550 560 570 580 590 600
480 490 500 510 520 530
pF1KA0 QPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTAL
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 QPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPA---DLTAL
610 620 630 640 650 660
540 550 560 570 580 590
pF1KA0 AKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLS
670 680 690 700 710 720
600 610 620 630 640 650
pF1KA0 NGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLL
730 740 750 760 770 780
660 670 680 690 700 710
pF1KA0 QISPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QISPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRF
790 800 810 820 830 840
720 730 740 750 760 770
pF1KA0 NSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGK
850 860 870 880 890 900
780 790 800 810 820 830
pF1KA0 KDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSV
910 920 930 940 950 960
840 850 860 870 880 890
pF1KA0 EVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVY
970 980 990 1000 1010 1020
900 910 920 930 940 950
pF1KA0 DIYLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIYLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQ
1030 1040 1050 1060 1070 1080
960 970 980 990 1000 1010
pF1KA0 WGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFAS
1090 1100 1110 1120 1130 1140
1020 1030
pF1KA0 VRSGGSSQVYFMTLGRTSLLSW
::::::::::::::::::::::
XP_016 VRSGGSSQVYFMTLGRTSLLSW
1150 1160
>--
initn: 601 init1: 601 opt: 601 Z-score: 250.5 bits: 58.1 E(85289): 3.3e-07
Smith-Waterman score: 601; 100.0% identity (100.0% similar) in 94 aa overlap (1-94:1-94)
10 20 30 40 50 60
pF1KA0 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
::::::::::::::::::::::::::::::::::
XP_016 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
XP_016 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
>>XP_016860858 (OMIM: 604666) PREDICTED: mitogen-activat (1196 aa)
initn: 6508 init1: 3925 opt: 4314 Z-score: 1627.8 bits: 313.0 E(85289): 6.2e-84
Smith-Waterman score: 5721; 85.0% identity (85.0% similar) in 1070 aa overlap (128-1037:128-1196)
100 110 120 130 140 150
pF1KA0 DDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQ
::::::::::::::::::::::::::::::
XP_016 DDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQ
100 110 120 130 140 150
160 170 180 190 200 210
pF1KA0 NVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLW
160 170 180 190 200 210
220 230 240 250 260 270
pF1KA0 SCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQR
220 230 240 250 260 270
280 290 300 310 320 330
pF1KA0 PSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQE
280 290 300 310 320 330
340 350 360 370 380
pF1KA0 GEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQE------------
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQK
340 350 360 370 380 390
pF1KA0 ------------------------------------------------------------
XP_016 RIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEE
400 410 420 430 440 450
pF1KA0 ------------------------------------------------------------
XP_016 KRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQE
460 470 480 490 500 510
390 400 410
pF1KA0 ----------------------------RSKPSFHAPEPKAHYEPADRAREVPVRTTSRS
::::::::::::::::::::::::::::::::
XP_016 QAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVPVRTTSRS
520 530 540 550 560 570
420 430 440 450 460 470
pF1KA0 PVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQP
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 PVLSRRDSPLQGSGQQNSQAGQRNSTS-IEPRLLWERVEKLVPRPGSGSSSGSSNSGSQP
580 590 600 610 620 630
480 490 500 510 520 530
pF1KA0 GSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAK
640 650 660 670 680 690
540 550 560 570 580 590
pF1KA0 ELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNG
700 710 720 730 740 750
600 610 620 630 640 650
pF1KA0 ETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQI
760 770 780 790 800 810
660 670 680 690 700 710
pF1KA0 SPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNS
820 830 840 850 860 870
720 730 740 750 760 770
pF1KA0 EILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKD
880 890 900 910 920 930
780 790 800 810 820 830
pF1KA0 KLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEV
940 950 960 970 980 990
840 850 860 870 880 890
pF1KA0 YAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDI
1000 1010 1020 1030 1040 1050
900 910 920 930 940 950
pF1KA0 YLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWG
1060 1070 1080 1090 1100 1110
960 970 980 990 1000 1010
pF1KA0 EMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVR
1120 1130 1140 1150 1160 1170
1020 1030
pF1KA0 SGGSSQVYFMTLGRTSLLSW
::::::::::::::::::::
XP_016 SGGSSQVYFMTLGRTSLLSW
1180 1190
>--
initn: 831 init1: 831 opt: 831 Z-score: 335.6 bits: 73.9 E(85289): 5.9e-12
Smith-Waterman score: 831; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127)
10 20 30 40 50 60
pF1KA0 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
:::::::
XP_016 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
>>XP_016860863 (OMIM: 604666) PREDICTED: mitogen-activat (1158 aa)
initn: 6110 init1: 3431 opt: 4294 Z-score: 1620.6 bits: 311.6 E(85289): 1.6e-83
Smith-Waterman score: 5919; 87.2% identity (87.2% similar) in 1069 aa overlap (98-1037:98-1158)
70 80 90 100 110 120
pF1KA0 LEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKE
::::::::::::::::::::::::::::::
XP_016 LEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 NPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERS
310 320 330 340 350 360
370 380
pF1KA0 EALRRQQLLQEQQLREQE------------------------------------------
::::::::::::::::::
XP_016 EALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQ
370 380 390 400 410 420
pF1KA0 ------------------------------------------------------------
XP_016 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL
430 440 450 460 470 480
390 400 410
pF1KA0 ---------------------------RSKPSFHAPEPKAHYEPADRAREVPVRTTSRSP
:::::::::::::::::::::::::::::::::
XP_016 QEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVPVRTTSRSP
490 500 510 520 530 540
420 430 440 450 460 470
pF1KA0 VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG
550 560 570 580 590 600
480 490 500 510 520 530
pF1KA0 SHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKE
610 620 630 640 650 660
540 550 560 570 580 590
pF1KA0 LRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGE
670 680 690 700 710 720
600 610 620 630 640 650
pF1KA0 TESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQIS
730 740 750 760 770 780
660 670 680 690 700 710
pF1KA0 PSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSE
790 800 810 820 830 840
720 730 740 750 760 770
pF1KA0 ILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDK
850 860 870 880 890 900
780 790 800 810 820 830
pF1KA0 LRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVY
910 920 930 940 950 960
840 850 860 870 880 890
pF1KA0 AWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIY
970 980 990 1000 1010 1020
900 910 920 930 940 950
pF1KA0 LPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
:::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPTH--------IQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
1030 1040 1050 1060 1070
960 970 980 990 1000 1010
pF1KA0 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
1080 1090 1100 1110 1120 1130
1020 1030
pF1KA0 GGSSQVYFMTLGRTSLLSW
:::::::::::::::::::
XP_016 GGSSQVYFMTLGRTSLLSW
1140 1150
>--
initn: 629 init1: 629 opt: 629 Z-score: 260.9 bits: 60.0 E(85289): 8.6e-08
Smith-Waterman score: 629; 100.0% identity (100.0% similar) in 97 aa overlap (1-97:1-97)
10 20 30 40 50 60
pF1KA0 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
:::::::::::::::::::::::::::::::::::::
XP_016 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
XP_016 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
>>XP_006712932 (OMIM: 604666) PREDICTED: mitogen-activat (1189 aa)
initn: 6064 init1: 3417 opt: 4248 Z-score: 1603.4 bits: 308.5 E(85289): 1.4e-82
Smith-Waterman score: 5647; 84.3% identity (84.3% similar) in 1069 aa overlap (129-1037:129-1189)
100 110 120 130 140 150
pF1KA0 DQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQN
::::::::::::::::::::::::::::::
XP_006 DQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQN
100 110 120 130 140 150
160 170 180 190 200 210
pF1KA0 VLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWS
160 170 180 190 200 210
220 230 240 250 260 270
pF1KA0 CGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRP
220 230 240 250 260 270
280 290 300 310 320 330
pF1KA0 STEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEG
280 290 300 310 320 330
340 350 360 370 380
pF1KA0 EPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQE-------------
:::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKR
340 350 360 370 380 390
pF1KA0 ------------------------------------------------------------
XP_006 IEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEK
400 410 420 430 440 450
pF1KA0 ------------------------------------------------------------
XP_006 RRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQ
460 470 480 490 500 510
390 400 410
pF1KA0 ---------------------------RSKPSFHAPEPKAHYEPADRAREVPVRTTSRSP
:::::::::::::::::::::::::::::::::
XP_006 AYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVPVRTTSRSP
520 530 540 550 560 570
420 430 440 450 460 470
pF1KA0 VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG
580 590 600 610 620 630
480 490 500 510 520 530
pF1KA0 SHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKE
640 650 660 670 680 690
540 550 560 570 580 590
pF1KA0 LRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGE
700 710 720 730 740 750
600 610 620 630 640 650
pF1KA0 TESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQIS
760 770 780 790 800 810
660 670 680 690 700 710
pF1KA0 PSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSE
820 830 840 850 860 870
720 730 740 750 760 770
pF1KA0 ILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDK
880 890 900 910 920 930
780 790 800 810 820 830
pF1KA0 LRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVY
940 950 960 970 980 990
840 850 860 870 880 890
pF1KA0 AWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIY
1000 1010 1020 1030 1040 1050
900 910 920 930 940 950
pF1KA0 LPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
:::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPTH--------IQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
1060 1070 1080 1090 1100 1110
960 970 980 990 1000 1010
pF1KA0 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
1120 1130 1140 1150 1160 1170
1020 1030
pF1KA0 GGSSQVYFMTLGRTSLLSW
:::::::::::::::::::
XP_006 GGSSQVYFMTLGRTSLLSW
1180
>--
initn: 839 init1: 839 opt: 839 Z-score: 338.6 bits: 74.5 E(85289): 4e-12
Smith-Waterman score: 839; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128)
10 20 30 40 50 60
pF1KA0 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::
XP_006 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
>>XP_016860859 (OMIM: 604666) PREDICTED: mitogen-activat (1188 aa)
initn: 5655 init1: 3008 opt: 4231 Z-score: 1597.1 bits: 307.3 E(85289): 3.2e-82
Smith-Waterman score: 5638; 84.2% identity (84.2% similar) in 1070 aa overlap (128-1037:128-1188)
100 110 120 130 140 150
pF1KA0 DDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQ
::::::::::::::::::::::::::::::
XP_016 DDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQ
100 110 120 130 140 150
160 170 180 190 200 210
pF1KA0 NVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLW
160 170 180 190 200 210
220 230 240 250 260 270
pF1KA0 SCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQR
220 230 240 250 260 270
280 290 300 310 320 330
pF1KA0 PSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQE
280 290 300 310 320 330
340 350 360 370 380
pF1KA0 GEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQE------------
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQK
340 350 360 370 380 390
pF1KA0 ------------------------------------------------------------
XP_016 RIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEE
400 410 420 430 440 450
pF1KA0 ------------------------------------------------------------
XP_016 KRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQE
460 470 480 490 500 510
390 400 410
pF1KA0 ----------------------------RSKPSFHAPEPKAHYEPADRAREVPVRTTSRS
::::::::::::::::::::::::::::::::
XP_016 QAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVPVRTTSRS
520 530 540 550 560 570
420 430 440 450 460 470
pF1KA0 PVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQP
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 PVLSRRDSPLQGSGQQNSQAGQRNSTS-IEPRLLWERVEKLVPRPGSGSSSGSSNSGSQP
580 590 600 610 620 630
480 490 500 510 520 530
pF1KA0 GSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAK
640 650 660 670 680 690
540 550 560 570 580 590
pF1KA0 ELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNG
700 710 720 730 740 750
600 610 620 630 640 650
pF1KA0 ETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQI
760 770 780 790 800 810
660 670 680 690 700 710
pF1KA0 SPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNS
820 830 840 850 860 870
720 730 740 750 760 770
pF1KA0 EILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKD
880 890 900 910 920 930
780 790 800 810 820 830
pF1KA0 KLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEV
940 950 960 970 980 990
840 850 860 870 880 890
pF1KA0 YAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDI
1000 1010 1020 1030 1040 1050
900 910 920 930 940 950
pF1KA0 YLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWG
::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLPTH--------IQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWG
1060 1070 1080 1090 1100
960 970 980 990 1000 1010
pF1KA0 EMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVR
1110 1120 1130 1140 1150 1160
1020 1030
pF1KA0 SGGSSQVYFMTLGRTSLLSW
::::::::::::::::::::
XP_016 SGGSSQVYFMTLGRTSLLSW
1170 1180
>--
initn: 831 init1: 831 opt: 831 Z-score: 335.7 bits: 73.9 E(85289): 5.9e-12
Smith-Waterman score: 831; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127)
10 20 30 40 50 60
pF1KA0 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
:::::::
XP_016 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
>>XP_016860855 (OMIM: 604666) PREDICTED: mitogen-activat (1243 aa)
initn: 4146 init1: 4146 opt: 4152 Z-score: 1567.5 bits: 301.9 E(85289): 1.4e-80
Smith-Waterman score: 5325; 80.7% identity (80.7% similar) in 1069 aa overlap (175-1037:175-1243)
150 160 170 180 190 200
pF1KA0 HIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDE
::::::::::::::::::::::::::::::
XP_016 HIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDE
150 160 170 180 190 200
210 220 230 240 250 260
pF1KA0 NPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFS
210 220 230 240 250 260
270 280 290 300 310 320
pF1KA0 FIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYS
270 280 290 300 310 320
330 340 350 360 370 380
pF1KA0 GSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQ
330 340 350 360 370 380
pF1KA0 E-----------------------------------------------------------
:
XP_016 EEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERR
390 400 410 420 430 440
pF1KA0 ------------------------------------------------------------
XP_016 RKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDHRRPHPQH
450 460 470 480 490 500
390 400
pF1KA0 ----------RSKPSFHAPEPKAHYEPADRAREV--------------------------
::::::::::::::::::::::::
XP_016 SQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVQWSHLASLKNNVSPVSRSHSFSDPSP
510 520 530 540 550 560
410
pF1KA0 ---------------------------------------------------PVRTTSRSP
:::::::::
XP_016 KFAHHHLRSQDPCPPSRSEVLSQSSDSKSEAPDPTQKAWSRSDSDEVPPRVPVRTTSRSP
570 580 590 600 610 620
420 430 440 450 460 470
pF1KA0 VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG
630 640 650 660 670 680
480 490 500 510 520 530
pF1KA0 SHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKE
690 700 710 720 730 740
540 550 560 570 580 590
pF1KA0 LRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGE
750 760 770 780 790 800
600 610 620 630 640 650
pF1KA0 TESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQIS
810 820 830 840 850 860
660 670 680 690 700 710
pF1KA0 PSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSE
870 880 890 900 910 920
720 730 740 750 760 770
pF1KA0 ILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDK
930 940 950 960 970 980
780 790 800 810 820 830
pF1KA0 LRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVY
990 1000 1010 1020 1030 1040
840 850 860 870 880 890
pF1KA0 AWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIY
1050 1060 1070 1080 1090 1100
900 910 920 930 940 950
pF1KA0 LPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
1110 1120 1130 1140 1150 1160
960 970 980 990 1000 1010
pF1KA0 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
1170 1180 1190 1200 1210 1220
1020 1030
pF1KA0 GGSSQVYFMTLGRTSLLSW
:::::::::::::::::::
XP_016 GGSSQVYFMTLGRTSLLSW
1230 1240
>--
initn: 1142 init1: 1142 opt: 1142 Z-score: 450.8 bits: 95.3 E(85289): 2.3e-18
Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 174 aa overlap (1-174:1-174)
10 20 30 40 50 60
pF1KA0 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMR
XP_016 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
>>XP_016860848 (OMIM: 604666) PREDICTED: mitogen-activat (1274 aa)
initn: 4146 init1: 4146 opt: 4152 Z-score: 1567.4 bits: 301.9 E(85289): 1.4e-80
Smith-Waterman score: 5046; 77.8% identity (77.8% similar) in 1069 aa overlap (206-1037:206-1274)
180 190 200 210 220 230
pF1KA0 AQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCD
::::::::::::::::::::::::::::::
XP_016 AQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KA0 MHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KA0 RQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRD
300 310 320 330 340 350
360 370 380
pF1KA0 FLRLQQENKERSEALRRQQLLQEQQLREQE------------------------------
::::::::::::::::::::::::::::::
XP_016 FLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRR
360 370 380 390 400 410
pF1KA0 ------------------------------------------------------------
XP_016 EREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEE
420 430 440 450 460 470
pF1KA0 ------------------------------------------------------------
XP_016 QRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQH
480 490 500 510 520 530
390 400
pF1KA0 ----------RSKPSFHAPEPKAHYEPADRAREV--------------------------
::::::::::::::::::::::::
XP_016 SQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVQWSHLASLKNNVSPVSRSHSFSDPSP
540 550 560 570 580 590
410
pF1KA0 ---------------------------------------------------PVRTTSRSP
:::::::::
XP_016 KFAHHHLRSQDPCPPSRSEVLSQSSDSKSEAPDPTQKAWSRSDSDEVPPRVPVRTTSRSP
600 610 620 630 640 650
420 430 440 450 460 470
pF1KA0 VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG
660 670 680 690 700 710
480 490 500 510 520 530
pF1KA0 SHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKE
720 730 740 750 760 770
540 550 560 570 580 590
pF1KA0 LRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGE
780 790 800 810 820 830
600 610 620 630 640 650
pF1KA0 TESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQIS
840 850 860 870 880 890
660 670 680 690 700 710
pF1KA0 PSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSE
900 910 920 930 940 950
720 730 740 750 760 770
pF1KA0 ILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDK
960 970 980 990 1000 1010
780 790 800 810 820 830
pF1KA0 LRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVY
1020 1030 1040 1050 1060 1070
840 850 860 870 880 890
pF1KA0 AWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIY
1080 1090 1100 1110 1120 1130
900 910 920 930 940 950
pF1KA0 LPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
1140 1150 1160 1170 1180 1190
960 970 980 990 1000 1010
pF1KA0 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
1200 1210 1220 1230 1240 1250
1020 1030
pF1KA0 GGSSQVYFMTLGRTSLLSW
:::::::::::::::::::
XP_016 GGSSQVYFMTLGRTSLLSW
1260 1270
>--
initn: 1359 init1: 1359 opt: 1359 Z-score: 531.2 bits: 110.2 E(85289): 7.6e-23
Smith-Waterman score: 1359; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205)
10 20 30 40 50 60
pF1KA0 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMR
:::::::::::::::::::::::::
XP_016 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
>>XP_016860849 (OMIM: 604666) PREDICTED: mitogen-activat (1273 aa)
initn: 6508 init1: 3925 opt: 4135 Z-score: 1561.1 bits: 300.8 E(85289): 3.3e-80
Smith-Waterman score: 5036; 77.8% identity (77.8% similar) in 1070 aa overlap (205-1037:205-1273)
180 190 200 210 220 230
pF1KA0 SAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLC
::::::::::::::::::::::::::::::
XP_016 SAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLC
180 190 200 210 220 230
240 250 260 270 280 290
pF1KA0 DMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KA0 ERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRR
300 310 320 330 340 350
360 370 380
pF1KA0 DFLRLQQENKERSEALRRQQLLQEQQLREQE-----------------------------
:::::::::::::::::::::::::::::::
XP_016 DFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQR
360 370 380 390 400 410
pF1KA0 ------------------------------------------------------------
XP_016 REREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEE
420 430 440 450 460 470
pF1KA0 ------------------------------------------------------------
XP_016 EQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQ
480 490 500 510 520 530
390 400
pF1KA0 -----------RSKPSFHAPEPKAHYEPADRAREV-------------------------
::::::::::::::::::::::::
XP_016 HSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVQWSHLASLKNNVSPVSRSHSFSDPS
540 550 560 570 580 590
410
pF1KA0 ----------------------------------------------------PVRTTSRS
::::::::
XP_016 PKFAHHHLRSQDPCPPSRSEVLSQSSDSKSEAPDPTQKAWSRSDSDEVPPRVPVRTTSRS
600 610 620 630 640 650
420 430 440 450 460 470
pF1KA0 PVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQP
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 PVLSRRDSPLQGSGQQNSQAGQRNSTS-IEPRLLWERVEKLVPRPGSGSSSGSSNSGSQP
660 670 680 690 700 710
480 490 500 510 520 530
pF1KA0 GSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAK
720 730 740 750 760 770
540 550 560 570 580 590
pF1KA0 ELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNG
780 790 800 810 820 830
600 610 620 630 640 650
pF1KA0 ETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQI
840 850 860 870 880 890
660 670 680 690 700 710
pF1KA0 SPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNS
900 910 920 930 940 950
720 730 740 750 760 770
pF1KA0 EILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKD
960 970 980 990 1000 1010
780 790 800 810 820 830
pF1KA0 KLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEV
1020 1030 1040 1050 1060 1070
840 850 860 870 880 890
pF1KA0 YAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDI
1080 1090 1100 1110 1120 1130
900 910 920 930 940 950
pF1KA0 YLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWG
1140 1150 1160 1170 1180 1190
960 970 980 990 1000 1010
pF1KA0 EMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVR
1200 1210 1220 1230 1240 1250
1020 1030
pF1KA0 SGGSSQVYFMTLGRTSLLSW
::::::::::::::::::::
XP_016 SGGSSQVYFMTLGRTSLLSW
1260 1270
>--
initn: 1352 init1: 1352 opt: 1352 Z-score: 528.6 bits: 109.7 E(85289): 1.1e-22
Smith-Waterman score: 1352; 100.0% identity (100.0% similar) in 204 aa overlap (1-204:1-204)
10 20 30 40 50 60
pF1KA0 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::
XP_016 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
1037 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:32:53 2016 done: Wed Nov 2 19:32:55 2016
Total Scan time: 14.920 Total Display time: 0.450
Function used was FASTA [36.3.4 Apr, 2011]