FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0691, 753 aa 1>>>pF1KA0691 753 - 753 aa - 753 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 17.3919+/-0.000496; mu= -34.0854+/- 0.031 mean_var=826.0146+/-171.689, 0's: 0 Z-trim(125.1): 29 B-trim: 0 in 0/61 Lambda= 0.044625 statistics sampled from 48148 (48193) to 48148 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.565), width: 16 Scan time: 14.900 The best scores are: opt bits E(85289) NP_055331 (OMIM: 604910) CCR4-NOT transcription co ( 753) 5080 342.6 3.6e-93 XP_005278339 (OMIM: 604910) PREDICTED: CCR4-NOT tr ( 754) 5068 341.8 6.1e-93 XP_005278338 (OMIM: 604910) PREDICTED: CCR4-NOT tr ( 770) 4851 327.9 9.9e-89 XP_011525294 (OMIM: 604910) PREDICTED: CCR4-NOT tr ( 757) 4839 327.1 1.7e-88 XP_005278336 (OMIM: 604910) PREDICTED: CCR4-NOT tr ( 771) 4839 327.1 1.7e-88 XP_005278337 (OMIM: 604910) PREDICTED: CCR4-NOT tr ( 771) 4839 327.1 1.7e-88 XP_011525295 (OMIM: 604910) PREDICTED: CCR4-NOT tr ( 682) 4547 308.3 7e-83 >>NP_055331 (OMIM: 604910) CCR4-NOT transcription comple (753 aa) initn: 5080 init1: 5080 opt: 5080 Z-score: 1793.8 bits: 342.6 E(85289): 3.6e-93 Smith-Waterman score: 5080; 100.0% identity (100.0% similar) in 753 aa overlap (1-753:1-753) 10 20 30 40 50 60 pF1KA0 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 AKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 GKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 EFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFE 670 680 690 700 710 720 730 740 750 pF1KA0 QGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ ::::::::::::::::::::::::::::::::: NP_055 QGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ 730 740 750 >>XP_005278339 (OMIM: 604910) PREDICTED: CCR4-NOT transc (754 aa) initn: 4057 init1: 4057 opt: 5068 Z-score: 1789.6 bits: 341.8 E(85289): 6.1e-93 Smith-Waterman score: 5068; 99.9% identity (99.9% similar) in 754 aa overlap (1-753:1-754) 10 20 30 40 50 60 pF1KA0 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKD-KQDRIEGLKRHIEKHRYH ::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::: XP_005 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDQKQDRIEGLKRHIEKHRYH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 VRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 ATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 PAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 AGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 LSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA0 CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDT 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA0 VEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEF 670 680 690 700 710 720 720 730 740 750 pF1KA0 EQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ :::::::::::::::::::::::::::::::::: XP_005 EQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ 730 740 750 >>XP_005278338 (OMIM: 604910) PREDICTED: CCR4-NOT transc (770 aa) initn: 4851 init1: 4851 opt: 4851 Z-score: 1714.0 bits: 327.9 E(85289): 9.9e-89 Smith-Waterman score: 5036; 97.8% identity (97.8% similar) in 770 aa overlap (1-753:1-770) 10 20 30 40 50 60 pF1KA0 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 AKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 GKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 EFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFE 670 680 690 700 710 720 730 740 750 pF1KA0 Q-----------------GTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ : :::::::::::::::::::::::::::::::: XP_005 QIPDHLLVHSLTAFSPGQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ 730 740 750 760 770 >>XP_011525294 (OMIM: 604910) PREDICTED: CCR4-NOT transc (757 aa) initn: 3828 init1: 3828 opt: 4839 Z-score: 1709.9 bits: 327.1 E(85289): 1.7e-88 Smith-Waterman score: 4839; 99.9% identity (99.9% similar) in 722 aa overlap (1-721:1-722) 10 20 30 40 50 60 pF1KA0 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKD-KQDRIEGLKRHIEKHRYH ::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::: XP_011 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDQKQDRIEGLKRHIEKHRYH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 VRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 ATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 PAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 AGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 LSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA0 CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDT 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA0 VEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEF 670 680 690 700 710 720 720 730 740 750 pF1KA0 EQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ :: XP_011 EQLAQSLSLTKYSSLWLSAQPGTPPSHPPLGQLLGLL 730 740 750 >>XP_005278336 (OMIM: 604910) PREDICTED: CCR4-NOT transc (771 aa) initn: 3828 init1: 3828 opt: 4839 Z-score: 1709.8 bits: 327.1 E(85289): 1.7e-88 Smith-Waterman score: 5024; 97.7% identity (97.7% similar) in 771 aa overlap (1-753:1-771) 10 20 30 40 50 60 pF1KA0 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKD-KQDRIEGLKRHIEKHRYH ::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::: XP_005 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDQKQDRIEGLKRHIEKHRYH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 VRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 ATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 PAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 AGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 LSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA0 CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDT 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA0 VEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEF 670 680 690 700 710 720 720 730 740 750 pF1KA0 EQ-----------------GTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ :: :::::::::::::::::::::::::::::::: XP_005 EQIPDHLLVHSLTAFSPGQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ 730 740 750 760 770 >>XP_005278337 (OMIM: 604910) PREDICTED: CCR4-NOT transc (771 aa) initn: 3828 init1: 3828 opt: 4839 Z-score: 1709.8 bits: 327.1 E(85289): 1.7e-88 Smith-Waterman score: 5024; 97.7% identity (97.7% similar) in 771 aa overlap (1-753:1-771) 10 20 30 40 50 60 pF1KA0 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKD-KQDRIEGLKRHIEKHRYH ::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::: XP_005 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDQKQDRIEGLKRHIEKHRYH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 VRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 ATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 PAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 AGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 LSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA0 CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDT 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA0 VEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEF 670 680 690 700 710 720 720 730 740 750 pF1KA0 EQ-----------------GTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ :: :::::::::::::::::::::::::::::::: XP_005 EQIPDHLLVHSLTAFSPGQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ 730 740 750 760 770 >>XP_011525295 (OMIM: 604910) PREDICTED: CCR4-NOT transc (682 aa) initn: 3536 init1: 3536 opt: 4547 Z-score: 1608.9 bits: 308.3 E(85289): 7e-83 Smith-Waterman score: 4547; 99.9% identity (99.9% similar) in 680 aa overlap (1-679:1-680) 10 20 30 40 50 60 pF1KA0 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKD-KQDRIEGLKRHIEKHRYH ::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::: XP_011 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDQKQDRIEGLKRHIEKHRYH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 VRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 ATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 PAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 AGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 LSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA0 CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDT 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA0 VEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEF :::::::::::::::::::: XP_011 VEFYQRLSTETLFFIFYYLELL 670 680 753 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:03:07 2016 done: Thu Nov 3 10:03:09 2016 Total Scan time: 14.900 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]