FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0700, 1130 aa 1>>>pF1KA0700 1130 - 1130 aa - 1130 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5922+/-0.00096; mu= 9.1779+/- 0.059 mean_var=186.8007+/-37.325, 0's: 0 Z-trim(111.8): 5 B-trim: 0 in 0/54 Lambda= 0.093839 statistics sampled from 12633 (12637) to 12633 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.388), width: 16 Scan time: 4.960 The best scores are: opt bits E(32554) CCDS74308.1 SIN3B gene_id:23309|Hs108|chr19 (1130) 7586 1040.1 0 CCDS77254.1 SIN3B gene_id:23309|Hs108|chr19 ( 720) 4759 657.2 3.8e-188 CCDS32946.1 SIN3B gene_id:23309|Hs108|chr19 (1162) 4757 657.1 6.8e-188 CCDS10279.1 SIN3A gene_id:25942|Hs108|chr15 (1273) 1885 268.3 8.1e-71 >>CCDS74308.1 SIN3B gene_id:23309|Hs108|chr19 (1130 aa) initn: 7586 init1: 7586 opt: 7586 Z-score: 5556.9 bits: 1040.1 E(32554): 0 Smith-Waterman score: 7586; 100.0% identity (100.0% similar) in 1130 aa overlap (1-1130:1-1130) 10 20 30 40 50 60 pF1KA0 MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 TYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 QSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 EIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 KYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 QFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 QFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAIC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 KKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 RLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 RLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 DEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 QFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 KEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 REMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 REMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVR 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 AARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 AARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 QYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 QYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESAC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KA0 VEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQYSRRPASP :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 VEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQYSRRPASP 1090 1100 1110 1120 1130 >>CCDS77254.1 SIN3B gene_id:23309|Hs108|chr19 (720 aa) initn: 4759 init1: 4759 opt: 4759 Z-score: 3491.3 bits: 657.2 E(32554): 3.8e-188 Smith-Waterman score: 4759; 99.9% identity (100.0% similar) in 709 aa overlap (422-1130:12-720) 400 410 420 430 440 450 pF1KA0 ASCKRIGSSYRALPKTYQQPKCSGRTAICKEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQ .::::::::::::::::::::::::::::: CCDS77 MQRHSRHFLLVQVLNDTWVSFPSWSEDSTFVSSKKTPYEEQ 10 20 30 40 460 470 480 490 500 510 pF1KA0 LHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRA 50 60 70 80 90 100 520 530 540 550 560 570 pF1KA0 IYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 IYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKS 110 120 130 140 150 160 580 590 600 610 620 630 pF1KA0 LDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILE 170 180 190 200 210 220 640 650 660 670 680 690 pF1KA0 DAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQ 230 240 250 260 270 280 700 710 720 730 740 750 pF1KA0 TTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYF 290 300 310 320 330 340 760 770 780 790 800 810 pF1KA0 FLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 FLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVE 350 360 370 380 390 400 820 830 840 850 860 870 pF1KA0 LEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSD 410 420 430 440 450 460 880 890 900 910 920 930 pF1KA0 DVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQ 470 480 490 500 510 520 940 950 960 970 980 990 pF1KA0 VIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFR 530 540 550 560 570 580 1000 1010 1020 1030 1040 1050 pF1KA0 RRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCR 590 600 610 620 630 640 1060 1070 1080 1090 1100 1110 pF1KA0 AKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 AKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHV 650 660 670 680 690 700 1120 1130 pF1KA0 HGLPVTRYRVQYSRRPASP ::::::::::::::::::: CCDS77 HGLPVTRYRVQYSRRPASP 710 720 >>CCDS32946.1 SIN3B gene_id:23309|Hs108|chr19 (1162 aa) initn: 4757 init1: 4757 opt: 4757 Z-score: 3486.8 bits: 657.1 E(32554): 6.8e-188 Smith-Waterman score: 7512; 97.2% identity (97.2% similar) in 1162 aa overlap (1-1130:1-1162) 10 20 30 40 50 60 pF1KA0 MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 TYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 EIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 KYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 KYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 QFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAIC 370 380 390 400 410 420 430 440 pF1KA0 KE--------------------------------VLNDTWVSFPSWSEDSTFVSSKKTPY :: :::::::::::::::::::::::::: CCDS32 KELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPY 430 440 450 460 470 480 450 460 470 480 490 500 pF1KA0 EEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 EEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQ 490 500 510 520 530 540 510 520 530 540 550 560 pF1KA0 RRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 RRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAY 550 560 570 580 590 600 570 580 590 600 610 620 pF1KA0 LKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQ 610 620 630 640 650 660 630 640 650 660 670 680 pF1KA0 ILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 ILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSP 670 680 690 700 710 720 690 700 710 720 730 740 pF1KA0 QGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNN 730 740 750 760 770 780 750 760 770 780 790 800 pF1KA0 WYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 WYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPS 790 800 810 820 830 840 810 820 830 840 850 860 pF1KA0 EVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 EVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHL 850 860 870 880 890 900 870 880 890 900 910 920 pF1KA0 VSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 VSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQR 910 920 930 940 950 960 930 940 950 960 970 980 pF1KA0 KGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 KGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLK 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KA0 KFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 KFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGT 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KA0 LCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCET 1090 1100 1110 1120 1130 1140 1110 1120 1130 pF1KA0 VHVHGLPVTRYRVQYSRRPASP :::::::::::::::::::::: CCDS32 VHVHGLPVTRYRVQYSRRPASP 1150 1160 >>CCDS10279.1 SIN3A gene_id:25942|Hs108|chr15 (1273 aa) initn: 3914 init1: 1503 opt: 1885 Z-score: 1384.9 bits: 268.3 E(32554): 8.1e-71 Smith-Waterman score: 3851; 52.7% identity (75.8% similar) in 1162 aa overlap (44-1130:126-1273) 20 30 40 50 60 70 pF1KA0 GGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFK ::.::::::..:::.: .:: ::.:::::: CCDS10 GQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFK 100 110 120 130 140 150 80 90 100 110 120 pF1KA0 SQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSP---------- :::::::::: ::::::. :::::.:::.::: ::.:.. : .:. .: CCDS10 SQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHG 160 170 180 190 200 210 130 140 150 pF1KA0 ----------LTSQENSHNHGDGAEDFKQQVPYKEDKP-----------QVP-------- :: .... :. : : : .:: :.: CCDS10 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASP 220 230 240 250 260 270 160 170 180 190 pF1KA0 --------------------LESDS-VEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTY :.... ::::.::.::::::.:: .:.::..:::::::: CCDS10 RSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTY 280 290 300 310 320 330 200 210 220 230 240 250 pF1KA0 QKEQLNTR---GRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCE :::: :.. : ...:.::...:: ::..:::::::::::::.:. :.. .. : CCDS10 QKEQRNAKEAGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAE 340 350 360 370 380 390 260 270 280 290 pF1KA0 MHSVQKNEHD---KTPEHSRKRSRPSL----LR--PV--SAPAKKKMKLRGTKDLSIAAV . .:.: : :. . : .::: .: :. . :.::: :: . :: :.: . CCDS10 KVDSVRNDHGGTVKKPQLNNKPQRPSQNGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADA 400 410 420 430 440 450 300 310 320 330 340 350 pF1KA0 GKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELF .:.: : ::::::..:.: :.:::::::...::::..: .::.:::::::::::::: CCDS10 SKHGGGTESLFFDKVRKALRSAEAYENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELF 460 470 480 490 500 510 360 370 380 390 400 410 pF1KA0 AQFKSFLGVKE-LSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTA ::.::: :: . . ..:. .::. :::::::::.:::::::::.::::::.::: CCDS10 NWFKNFLGYKESVHLETYPKERATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTP 520 530 540 550 560 570 420 430 440 450 460 470 pF1KA0 ICKEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLES .::::::::::::::::::::::::::: :::...::::::::::::::::::::::::. CCDS10 LCKEVLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEA 580 590 600 610 620 630 480 490 500 510 520 530 pF1KA0 VQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVV .::::::.. :.: :::::..::::::::.:.:. :::.::: .::..:.::: :::.: CCDS10 IQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIV 640 650 660 670 680 690 540 550 560 570 580 590 pF1KA0 LKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIES ::::: :::::::::.::::.:::: :: ::::::::..::::::::.:::::::::::: CCDS10 LKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIES 700 710 720 730 740 750 600 610 620 630 640 650 pF1KA0 VYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQL .:::.::: .: .. ::: ..:::.:::::::::: ..:::: .:::::. :.:. CCDS10 IYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQI 760 770 780 790 800 810 660 670 680 690 700 710 pF1KA0 LHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGD .:.:.:.:.:.:. ::. :: .:. : .. : .... . : :::. : :.. CCDS10 MHHFIPDLLFAQRGDLSDVEEEEEEEMDVDEA--TGAVKKHNGVGG---SPPKSKLLFSN 820 830 840 850 860 870 720 730 740 750 760 770 pF1KA0 APATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYR . : . . .:.::.::..:::::.:.:::: :: :::.: ::..:. : CCDS10 TAAQKL---------RGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEEN 880 890 900 910 920 780 790 800 810 820 830 pF1KA0 TEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYED :.: :. . .:.:...::..::::.: .:..:.:::::::::::::.:.:: .:::: CCDS10 REREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSSQYED 930 940 950 960 970 980 840 850 860 870 880 890 pF1KA0 TLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRC .::::::::::..::::::.:.:.:::.:.:::..:..:..::: :.. ::.::.:... CCDS10 SLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQVTDLYLAENNNGATGGQLNTQN 990 1000 1010 1020 1030 1040 900 910 920 930 940 950 pF1KA0 VRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARY :. :..:: :::. :.::::::.::.: .::: .::::::::: ...::::... . : CCDS10 SRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAERWSDY 1050 1060 1070 1080 1090 1100 960 970 980 990 1000 1010 pF1KA0 VEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVES ::.:.... .: : . ::::: :::...:. .... . .:. .: : . .:.: CCDS10 VERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKEGKEGNSKKTMENVDS 1110 1120 1130 1140 1150 1160 1020 1030 1040 1050 1060 1070 pF1KA0 ACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDN ..:::::...:::....:::::::: .: ::.: . : : ::.:. : ..: ... CCDS10 LDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDKWTKEH 1170 1180 1190 1200 1210 1220 1080 1090 1100 1110 1120 1130 pF1KA0 VTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQYSRRPASP : : :. .. ::::: : .::: : :.: .: . ...:::.:. .: CCDS10 VPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSINKYRVKYGTVFKAP 1230 1240 1250 1260 1270 1130 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:57:08 2016 done: Fri Nov 4 00:57:09 2016 Total Scan time: 4.960 Total Display time: 0.210 Function used was FASTA [36.3.4 Apr, 2011]