FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0708, 2517 aa 1>>>pF1KA0708 2517 - 2517 aa - 2517 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8052+/-0.000406; mu= 15.7000+/- 0.026 mean_var=167.0189+/-33.685, 0's: 0 Z-trim(117.8): 148 B-trim: 308 in 1/53 Lambda= 0.099241 statistics sampled from 30055 (30211) to 30055 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.354), width: 16 Scan time: 22.310 The best scores are: opt bits E(85289) NP_055904 (OMIM: 607489) cullin-9 [Homo sapiens] (2517) 17077 2458.9 0 XP_011512730 (OMIM: 607489) PREDICTED: cullin-9 is (1851) 10282 1485.9 0 XP_011512728 (OMIM: 607489) PREDICTED: cullin-9 is (2339) 10282 1486.0 0 XP_016866078 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 10282 1486.1 0 XP_011512724 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 10282 1486.1 0 XP_011512725 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 10282 1486.1 0 XP_011512732 (OMIM: 607489) PREDICTED: cullin-9 is (1403) 9201 1331.1 0 XP_011512729 (OMIM: 607489) PREDICTED: cullin-9 is (2095) 7091 1029.1 0 XP_011512731 (OMIM: 607489) PREDICTED: cullin-9 is (1834) 6816 989.7 0 XP_016866079 (OMIM: 607489) PREDICTED: cullin-9 is (1909) 6816 989.7 0 XP_011512727 (OMIM: 607489) PREDICTED: cullin-9 is (2456) 6816 989.8 0 XP_011512726 (OMIM: 607489) PREDICTED: cullin-9 is (2539) 6816 989.8 0 NP_055595 (OMIM: 273750,609577) cullin-7 isoform 2 (1698) 3431 505.0 3.4e-141 XP_016867028 (OMIM: 273750,609577) PREDICTED: cull (1702) 3431 505.0 3.4e-141 XP_016867027 (OMIM: 273750,609577) PREDICTED: cull (1711) 3431 505.0 3.4e-141 XP_016867026 (OMIM: 273750,609577) PREDICTED: cull (1730) 3431 505.0 3.5e-141 XP_006715348 (OMIM: 273750,609577) PREDICTED: cull (1734) 3431 505.0 3.5e-141 XP_016867025 (OMIM: 273750,609577) PREDICTED: cull (1743) 3431 505.0 3.5e-141 XP_005249560 (OMIM: 273750,609577) PREDICTED: cull (1750) 3431 505.0 3.5e-141 XP_011513322 (OMIM: 273750,609577) PREDICTED: cull (1754) 3431 505.0 3.5e-141 XP_016867024 (OMIM: 273750,609577) PREDICTED: cull (1763) 3431 505.0 3.5e-141 NP_001161842 (OMIM: 273750,609577) cullin-7 isofor (1782) 3431 505.0 3.5e-141 XP_011513321 (OMIM: 273750,609577) PREDICTED: cull (1786) 3431 505.0 3.5e-141 XP_016867023 (OMIM: 273750,609577) PREDICTED: cull (1791) 3431 505.0 3.6e-141 XP_016867022 (OMIM: 273750,609577) PREDICTED: cull (1795) 3431 505.0 3.6e-141 XP_011513323 (OMIM: 273750,609577) PREDICTED: cull ( 989) 3051 450.4 5.4e-125 XP_016867029 (OMIM: 273750,609577) PREDICTED: cull ( 897) 1252 192.8 1.7e-47 XP_016861020 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493) 588 97.6 4.5e-19 NP_006312 (OMIM: 605615) E3 ubiquitin-protein liga ( 493) 588 97.6 4.5e-19 NP_001304262 (OMIM: 605615) E3 ubiquitin-protein l ( 493) 588 97.6 4.5e-19 XP_016861021 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493) 588 97.6 4.5e-19 XP_016861030 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409) 563 93.9 4.6e-18 XP_016861029 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409) 563 93.9 4.6e-18 XP_016861027 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 563 94.0 4.7e-18 XP_016861028 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 563 94.0 4.7e-18 XP_016861026 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 563 94.0 4.7e-18 XP_016861025 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 563 94.0 4.7e-18 XP_011531577 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 563 94.0 4.7e-18 NP_005735 (OMIM: 605624) E3 ubiquitin-protein liga ( 557) 517 87.5 5.6e-16 XP_011531567 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 496 84.4 4.3e-15 XP_011531568 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 496 84.4 4.3e-15 XP_011531570 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 496 84.4 4.3e-15 XP_011531569 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 496 84.4 4.3e-15 XP_011519741 (OMIM: 605624) PREDICTED: E3 ubiquiti ( 465) 489 83.4 7.9e-15 NP_001304263 (OMIM: 605615) E3 ubiquitin-protein l ( 351) 474 81.2 2.8e-14 XP_011531575 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 432) 471 80.8 4.4e-14 XP_011531573 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 471 80.8 4.5e-14 XP_016861022 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 471 80.8 4.5e-14 XP_011531572 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 471 80.8 4.5e-14 XP_016861024 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 471 80.8 4.5e-14 >>NP_055904 (OMIM: 607489) cullin-9 [Homo sapiens] (2517 aa) initn: 17077 init1: 17077 opt: 17077 Z-score: 13212.5 bits: 2458.9 E(85289): 0 Smith-Waterman score: 17077; 100.0% identity (100.0% similar) in 2517 aa overlap (1-2517:1-2517) 10 20 30 40 50 60 pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 LIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQ 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 IGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEE 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 EAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQN 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 HPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLS 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 PELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKD 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVA 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 CTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSP 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 EAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQ 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 SYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEY 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 LTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWC 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 TNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMS 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 VEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 AMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 QARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLL 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 2460 pF1KA0 RADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGP 2410 2420 2430 2440 2450 2460 2470 2480 2490 2500 2510 pF1KA0 EAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD 2470 2480 2490 2500 2510 >>XP_011512730 (OMIM: 607489) PREDICTED: cullin-9 isofor (1851 aa) initn: 10446 init1: 10282 opt: 10282 Z-score: 7956.5 bits: 1485.9 E(85289): 0 Smith-Waterman score: 11823; 97.3% identity (97.3% similar) in 1835 aa overlap (1-1786:1-1835) 10 20 30 40 50 60 pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAH---------------- :::::::::::::::::::::::::::::::::::::::::::: XP_011 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQV 1510 1520 1530 1540 1550 1560 1550 1560 1570 pF1KA0 ---------------------------------MSEQFARYIDQQIQGGLIGGAPGVEML ::::::::::::::::::::::::::: XP_011 HLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEML 1570 1580 1590 1600 1610 1620 1580 1590 1600 1610 1620 1630 pF1KA0 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ 1630 1640 1650 1660 1670 1680 1640 1650 1660 1670 1680 1690 pF1KA0 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP 1690 1700 1710 1720 1730 1740 1700 1710 1720 1730 1740 1750 pF1KA0 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR 1750 1760 1770 1780 1790 1800 1760 1770 1780 1790 1800 1810 pF1KA0 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL ::::::::::::::::::::::::::::::::::: XP_011 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTESCCSRHSCPSPQGMAL 1810 1820 1830 1840 1850 1820 1830 1840 1850 1860 1870 pF1KA0 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL >>XP_011512728 (OMIM: 607489) PREDICTED: cullin-9 isofor (2339 aa) initn: 15611 init1: 10282 opt: 10282 Z-score: 7955.1 bits: 1486.0 E(85289): 0 Smith-Waterman score: 15397; 97.8% identity (97.9% similar) in 2334 aa overlap (1-2285:1-2334) 10 20 30 40 50 60 pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAH---------------- :::::::::::::::::::::::::::::::::::::::::::: XP_011 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQV 1510 1520 1530 1540 1550 1560 1550 1560 1570 pF1KA0 ---------------------------------MSEQFARYIDQQIQGGLIGGAPGVEML ::::::::::::::::::::::::::: XP_011 HLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEML 1570 1580 1590 1600 1610 1620 1580 1590 1600 1610 1620 1630 pF1KA0 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ 1630 1640 1650 1660 1670 1680 1640 1650 1660 1670 1680 1690 pF1KA0 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP 1690 1700 1710 1720 1730 1740 1700 1710 1720 1730 1740 1750 pF1KA0 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR 1750 1760 1770 1780 1790 1800 1760 1770 1780 1790 1800 1810 pF1KA0 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL 1810 1820 1830 1840 1850 1860 1820 1830 1840 1850 1860 1870 pF1KA0 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL 1870 1880 1890 1900 1910 1920 1880 1890 1900 1910 1920 1930 pF1KA0 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL 1930 1940 1950 1960 1970 1980 1940 1950 1960 1970 1980 1990 pF1KA0 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL 1990 2000 2010 2020 2030 2040 2000 2010 2020 2030 2040 2050 pF1KA0 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL 2050 2060 2070 2080 2090 2100 2060 2070 2080 2090 2100 2110 pF1KA0 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL 2110 2120 2130 2140 2150 2160 2120 2130 2140 2150 2160 2170 pF1KA0 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC 2170 2180 2190 2200 2210 2220 2180 2190 2200 2210 2220 2230 pF1KA0 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL 2230 2240 2250 2260 2270 2280 2240 2250 2260 2270 2280 2290 pF1KA0 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK ::::::::::::::::::::::::::::::::::::::::::::::::::: :. XP_011 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMPSQRILAR 2290 2300 2310 2320 2330 2300 2310 2320 2330 2340 2350 pF1KA0 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV >>XP_016866078 (OMIM: 607489) PREDICTED: cullin-9 isofor (2566 aa) initn: 10396 init1: 10282 opt: 10282 Z-score: 7954.5 bits: 1486.1 E(85289): 0 Smith-Waterman score: 16851; 98.1% identity (98.1% similar) in 2549 aa overlap (1-2500:1-2549) 10 20 30 40 50 60 pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAH---------------- :::::::::::::::::::::::::::::::::::::::::::: XP_016 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQV 1510 1520 1530 1540 1550 1560 1550 1560 1570 pF1KA0 ---------------------------------MSEQFARYIDQQIQGGLIGGAPGVEML ::::::::::::::::::::::::::: XP_016 HLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEML 1570 1580 1590 1600 1610 1620 1580 1590 1600 1610 1620 1630 pF1KA0 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ 1630 1640 1650 1660 1670 1680 1640 1650 1660 1670 1680 1690 pF1KA0 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP 1690 1700 1710 1720 1730 1740 1700 1710 1720 1730 1740 1750 pF1KA0 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR 1750 1760 1770 1780 1790 1800 1760 1770 1780 1790 1800 1810 pF1KA0 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL 1810 1820 1830 1840 1850 1860 1820 1830 1840 1850 1860 1870 pF1KA0 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL 1870 1880 1890 1900 1910 1920 1880 1890 1900 1910 1920 1930 pF1KA0 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL 1930 1940 1950 1960 1970 1980 1940 1950 1960 1970 1980 1990 pF1KA0 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL 1990 2000 2010 2020 2030 2040 2000 2010 2020 2030 2040 2050 pF1KA0 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL 2050 2060 2070 2080 2090 2100 2060 2070 2080 2090 2100 2110 pF1KA0 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL 2110 2120 2130 2140 2150 2160 2120 2130 2140 2150 2160 2170 pF1KA0 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC 2170 2180 2190 2200 2210 2220 2180 2190 2200 2210 2220 2230 pF1KA0 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL 2230 2240 2250 2260 2270 2280 2240 2250 2260 2270 2280 2290 pF1KA0 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK 2290 2300 2310 2320 2330 2340 2300 2310 2320 2330 2340 2350 pF1KA0 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV 2350 2360 2370 2380 2390 2400 2360 2370 2380 2390 2400 2410 pF1KA0 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL 2410 2420 2430 2440 2450 2460 2420 2430 2440 2450 2460 2470 pF1KA0 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED 2470 2480 2490 2500 2510 2520 2480 2490 2500 2510 pF1KA0 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD ::::::::::::::::::::::::::::: XP_016 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD 2530 2540 2550 2560 >>XP_011512724 (OMIM: 607489) PREDICTED: cullin-9 isofor (2566 aa) initn: 10396 init1: 10282 opt: 10282 Z-score: 7954.5 bits: 1486.1 E(85289): 0 Smith-Waterman score: 16851; 98.1% identity (98.1% similar) in 2549 aa overlap (1-2500:1-2549) 10 20 30 40 50 60 pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAH---------------- :::::::::::::::::::::::::::::::::::::::::::: XP_011 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQV 1510 1520 1530 1540 1550 1560 1550 1560 1570 pF1KA0 ---------------------------------MSEQFARYIDQQIQGGLIGGAPGVEML ::::::::::::::::::::::::::: XP_011 HLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEML 1570 1580 1590 1600 1610 1620 1580 1590 1600 1610 1620 1630 pF1KA0 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ 1630 1640 1650 1660 1670 1680 1640 1650 1660 1670 1680 1690 pF1KA0 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP 1690 1700 1710 1720 1730 1740 1700 1710 1720 1730 1740 1750 pF1KA0 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR 1750 1760 1770 1780 1790 1800 1760 1770 1780 1790 1800 1810 pF1KA0 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL 1810 1820 1830 1840 1850 1860 1820 1830 1840 1850 1860 1870 pF1KA0 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL 1870 1880 1890 1900 1910 1920 1880 1890 1900 1910 1920 1930 pF1KA0 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL 1930 1940 1950 1960 1970 1980 1940 1950 1960 1970 1980 1990 pF1KA0 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL 1990 2000 2010 2020 2030 2040 2000 2010 2020 2030 2040 2050 pF1KA0 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL 2050 2060 2070 2080 2090 2100 2060 2070 2080 2090 2100 2110 pF1KA0 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL 2110 2120 2130 2140 2150 2160 2120 2130 2140 2150 2160 2170 pF1KA0 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC 2170 2180 2190 2200 2210 2220 2180 2190 2200 2210 2220 2230 pF1KA0 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL 2230 2240 2250 2260 2270 2280 2240 2250 2260 2270 2280 2290 pF1KA0 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK 2290 2300 2310 2320 2330 2340 2300 2310 2320 2330 2340 2350 pF1KA0 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV 2350 2360 2370 2380 2390 2400 2360 2370 2380 2390 2400 2410 pF1KA0 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL 2410 2420 2430 2440 2450 2460 2420 2430 2440 2450 2460 2470 pF1KA0 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED 2470 2480 2490 2500 2510 2520 2480 2490 2500 2510 pF1KA0 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD ::::::::::::::::::::::::::::: XP_011 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD 2530 2540 2550 2560 >>XP_011512725 (OMIM: 607489) PREDICTED: cullin-9 isofor (2566 aa) initn: 10396 init1: 10282 opt: 10282 Z-score: 7954.5 bits: 1486.1 E(85289): 0 Smith-Waterman score: 16851; 98.1% identity (98.1% similar) in 2549 aa overlap (1-2500:1-2549) 10 20 30 40 50 60 pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAH---------------- :::::::::::::::::::::::::::::::::::::::::::: XP_011 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQV 1510 1520 1530 1540 1550 1560 1550 1560 1570 pF1KA0 ---------------------------------MSEQFARYIDQQIQGGLIGGAPGVEML ::::::::::::::::::::::::::: XP_011 HLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEML 1570 1580 1590 1600 1610 1620 1580 1590 1600 1610 1620 1630 pF1KA0 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ 1630 1640 1650 1660 1670 1680 1640 1650 1660 1670 1680 1690 pF1KA0 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP 1690 1700 1710 1720 1730 1740 1700 1710 1720 1730 1740 1750 pF1KA0 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR 1750 1760 1770 1780 1790 1800 1760 1770 1780 1790 1800 1810 pF1KA0 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL 1810 1820 1830 1840 1850 1860 1820 1830 1840 1850 1860 1870 pF1KA0 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL 1870 1880 1890 1900 1910 1920 1880 1890 1900 1910 1920 1930 pF1KA0 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL 1930 1940 1950 1960 1970 1980 1940 1950 1960 1970 1980 1990 pF1KA0 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL 1990 2000 2010 2020 2030 2040 2000 2010 2020 2030 2040 2050 pF1KA0 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL 2050 2060 2070 2080 2090 2100 2060 2070 2080 2090 2100 2110 pF1KA0 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL 2110 2120 2130 2140 2150 2160 2120 2130 2140 2150 2160 2170 pF1KA0 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC 2170 2180 2190 2200 2210 2220 2180 2190 2200 2210 2220 2230 pF1KA0 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL 2230 2240 2250 2260 2270 2280 2240 2250 2260 2270 2280 2290 pF1KA0 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK 2290 2300 2310 2320 2330 2340 2300 2310 2320 2330 2340 2350 pF1KA0 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV 2350 2360 2370 2380 2390 2400 2360 2370 2380 2390 2400 2410 pF1KA0 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL 2410 2420 2430 2440 2450 2460 2420 2430 2440 2450 2460 2470 pF1KA0 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED 2470 2480 2490 2500 2510 2520 2480 2490 2500 2510 pF1KA0 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD ::::::::::::::::::::::::::::: XP_011 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD 2530 2540 2550 2560 >>XP_011512732 (OMIM: 607489) PREDICTED: cullin-9 isofor (1403 aa) initn: 9201 init1: 9201 opt: 9201 Z-score: 7121.7 bits: 1331.1 E(85289): 0 Smith-Waterman score: 9201; 100.0% identity (100.0% similar) in 1386 aa overlap (1-1386:1-1386) 10 20 30 40 50 60 pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP :::::: XP_011 QNITSPGLSPQCSSLLPAPGTAP 1390 1400 >>XP_011512729 (OMIM: 607489) PREDICTED: cullin-9 isofor (2095 aa) initn: 7205 init1: 7091 opt: 7091 Z-score: 5486.6 bits: 1029.1 E(85289): 0 Smith-Waterman score: 13660; 97.6% identity (97.6% similar) in 2078 aa overlap (472-2500:1-2078) 450 460 470 480 490 500 pF1KA0 ATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPYLQPEPQKNERVGYLTQAEWWE :::::::::::::::::::::::::::::: XP_011 MDGLYPLPYLQPEPQKNERVGYLTQAEWWE 10 20 30 510 520 530 540 550 560 pF1KA0 LLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVSVEMAESLLQVLSSRFEGSTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVSVEMAESLLQVLSSRFEGSTLN 40 50 60 70 80 90 570 580 590 600 610 620 pF1KA0 DLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKSEASFSEEETESLKAKAEAPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKSEASFSEEETESLKAKAEAPKT 100 110 120 130 140 150 630 640 650 660 670 680 pF1KA0 EAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEAASEMARALRGPGPRSSLDQHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEAASEMARALRGPGPRSSLDQHV 160 170 180 190 200 210 690 700 710 720 730 740 pF1KA0 AAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLVRPDRSLREKLVKMLVELLTNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLVRPDRSLREKLVKMLVELLTNQ 220 230 240 250 260 270 750 760 770 780 790 800 pF1KA0 VGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKML 280 290 300 310 320 330 810 820 830 840 850 860 pF1KA0 AVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTE 340 350 360 370 380 390 870 880 890 900 910 920 pF1KA0 GCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLL 400 410 420 430 440 450 930 940 950 960 970 980 pF1KA0 NRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAV 460 470 480 490 500 510 990 1000 1010 1020 1030 1040 pF1KA0 RPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCL 520 530 540 550 560 570 1050 1060 1070 1080 1090 1100 pF1KA0 NCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCEL 580 590 600 610 620 630 1110 1120 1130 1140 1150 1160 pF1KA0 RDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSS 640 650 660 670 680 690 1170 1180 1190 1200 1210 1220 pF1KA0 VEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLL 700 710 720 730 740 750 1230 1240 1250 1260 1270 1280 pF1KA0 VASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRC 760 770 780 790 800 810 1290 1300 1310 1320 1330 1340 pF1KA0 QQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCP 820 830 840 850 860 870 1350 1360 1370 1380 1390 1400 pF1KA0 RLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQY 880 890 900 910 920 930 1410 1420 1430 1440 1450 1460 pF1KA0 LEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPS 940 950 960 970 980 990 1470 1480 1490 1500 1510 1520 pF1KA0 PVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAA 1000 1010 1020 1030 1040 1050 1530 1540 pF1KA0 FMLALRSGFSGALLQQSFLTAAH------------------------------------- ::::::::::::::::::::::: XP_011 FMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQVHLFLLCPFTSFRSPVSYSTPS 1060 1070 1080 1090 1100 1110 1550 1560 1570 1580 1590 pF1KA0 ------------MSEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATT :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATT 1120 1130 1140 1150 1160 1170 1600 1610 1620 1630 1640 1650 pF1KA0 FEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQL 1180 1190 1200 1210 1220 1230 1660 1670 1680 1690 1700 1710 pF1KA0 QRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCY 1240 1250 1260 1270 1280 1290 1720 1730 1740 1750 1760 1770 pF1KA0 LYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVS 1300 1310 1320 1330 1340 1350 1780 1790 1800 1810 1820 1830 pF1KA0 TVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVL 1360 1370 1380 1390 1400 1410 1840 1850 1860 1870 1880 1890 pF1KA0 RLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQ 1420 1430 1440 1450 1460 1470 1900 1910 1920 1930 1940 1950 pF1KA0 LVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYA 1480 1490 1500 1510 1520 1530 1960 1970 1980 1990 2000 2010 pF1KA0 APEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQ 1540 1550 1560 1570 1580 1590 2020 2030 2040 2050 2060 2070 pF1KA0 VQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPV 1600 1610 1620 1630 1640 1650 2080 2090 2100 2110 2120 2130 pF1KA0 CVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAI 1660 1670 1680 1690 1700 1710 2140 2150 2160 2170 2180 2190 pF1KA0 VSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNC 1720 1730 1740 1750 1760 1770 2200 2210 2220 2230 2240 2250 pF1KA0 SFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHM 1780 1790 1800 1810 1820 1830 2260 2270 2280 2290 2300 2310 pF1KA0 TCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVN 1840 1850 1860 1870 1880 1890 2320 2330 2340 2350 2360 2370 pF1KA0 LRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENL 1900 1910 1920 1930 1940 1950 2380 2390 2400 2410 2420 2430 pF1KA0 ELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRV 1960 1970 1980 1990 2000 2010 2440 2450 2460 2470 2480 2490 pF1KA0 GLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSY 2020 2030 2040 2050 2060 2070 2500 2510 pF1KA0 DESENLDQETFFFGDEEEDEDEAYD :::::::: XP_011 DESENLDQETFFFGDEEEDEDEAYD 2080 2090 >>XP_011512731 (OMIM: 607489) PREDICTED: cullin-9 isofor (1834 aa) initn: 6802 init1: 6802 opt: 6816 Z-score: 5274.6 bits: 989.7 E(85289): 0 Smith-Waterman score: 12111; 97.3% identity (97.3% similar) in 1834 aa overlap (733-2517:1-1834) 710 720 730 740 750 760 pF1KA0 SALSQAVEEVTERDHPLVRPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKH :::::::::::::::::::::::::::::: XP_011 MLVELLTNQVGEKMVVVQALRLLYLLMTKH 10 20 30 770 780 790 800 810 820 pF1KA0 EWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSL 40 50 60 70 80 90 830 840 850 860 870 880 pF1KA0 FDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHH 100 110 120 130 140 150 890 900 910 920 930 940 pF1KA0 TLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQ 160 170 180 190 200 210 950 960 970 980 990 1000 pF1KA0 GQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTL 220 230 240 250 260 270 1010 1020 1030 1040 1050 1060 pF1KA0 DAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLH 280 290 300 310 320 330 1070 1080 1090 1100 1110 1120 pF1KA0 RLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSI 340 350 360 370 380 390 1130 1140 1150 1160 1170 1180 pF1KA0 LAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRA 400 410 420 430 440 450 1190 1200 1210 1220 1230 1240 pF1KA0 SKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDST 460 470 480 490 500 510 1250 1260 1270 1280 1290 1300 pF1KA0 SCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTF 520 530 540 550 560 570 1310 1320 1330 1340 1350 1360 pF1KA0 WPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDE 580 590 600 610 620 630 1370 1380 1390 1400 1410 1420 pF1KA0 AAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRV 640 650 660 670 680 690 1430 1440 1450 1460 1470 1480 pF1KA0 RRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQE 700 710 720 730 740 750 1490 1500 1510 1520 1530 1540 pF1KA0 QVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTA 760 770 780 790 800 810 1550 pF1KA0 AH-------------------------------------------------MSEQFARYI :: ::::::::: XP_011 AHVSPTSSPQGYKLVFQVHLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYI 820 830 840 850 860 870 1560 1570 1580 1590 1600 1610 pF1KA0 DQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWL 880 890 900 910 920 930 1620 1630 1640 1650 1660 1670 pF1KA0 EGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEE 940 950 960 970 980 990 1680 1690 1700 1710 1720 1730 pF1KA0 EEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSS 1000 1010 1020 1030 1040 1050 1740 1750 1760 1770 1780 1790 pF1KA0 FYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETL 1060 1070 1080 1090 1100 1110 1800 1810 1820 1830 1840 1850 pF1KA0 LKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQA 1120 1130 1140 1150 1160 1170 1860 1870 1880 1890 1900 1910 pF1KA0 YLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGH 1180 1190 1200 1210 1220 1230 1920 1930 1940 1950 1960 1970 pF1KA0 TVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQS 1240 1250 1260 1270 1280 1290 1980 1990 2000 2010 2020 2030 pF1KA0 ETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHW 1300 1310 1320 1330 1340 1350 2040 2050 2060 2070 2080 2090 pF1KA0 GAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCC 1360 1370 1380 1390 1400 1410 2100 2110 2120 2130 2140 2150 pF1KA0 KSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVES 1420 1430 1440 1450 1460 1470 2160 2170 2180 2190 2200 2210 pF1KA0 CSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDG 1480 1490 1500 1510 1520 1530 2220 2230 2240 2250 2260 2270 pF1KA0 GYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNH 1540 1550 1560 1570 1580 1590 2280 2290 2300 2310 2320 2330 pF1KA0 KDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLN 1600 1610 1620 1630 1640 1650 2340 2350 2360 2370 2380 2390 pF1KA0 DACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDL 1660 1670 1680 1690 1700 1710 2400 2410 2420 2430 2440 2450 pF1KA0 ASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQ 1720 1730 1740 1750 1760 1770 2460 2470 2480 2490 2500 2510 pF1KA0 PQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDED 1780 1790 1800 1810 1820 1830 pF1KA0 EAYD :::: XP_011 EAYD >>XP_016866079 (OMIM: 607489) PREDICTED: cullin-9 isofor (1909 aa) initn: 6802 init1: 6802 opt: 6816 Z-score: 5274.4 bits: 989.7 E(85289): 0 Smith-Waterman score: 12545; 97.4% identity (97.4% similar) in 1904 aa overlap (663-2517:6-1909) 640 650 660 670 680 690 pF1KA0 PMAQSDSQLFNQLLVTEGMTLPTEMKEAASEMARALRGPGPRSSLDQHVAAVVATVQISS :::::::::::::::::::::::::::::: XP_016 MCLNIEMARALRGPGPRSSLDQHVAAVVATVQISS 10 20 30 700 710 720 730 740 750 pF1KA0 LDTNLQLSGLSALSQAVEEVTERDHPLVRPDRSLREKLVKMLVELLTNQVGEKMVVVQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDTNLQLSGLSALSQAVEEVTERDHPLVRPDRSLREKLVKMLVELLTNQVGEKMVVVQAL 40 50 60 70 80 90 760 770 780 790 800 810 pF1KA0 RLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAVASSSEIPTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAVASSSEIPTF 100 110 120 130 140 150 820 830 840 850 860 870 pF1KA0 VTGRDSIHSLFDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTEGCSSAARNGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTGRDSIHSLFDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTEGCSSAARNGLL 160 170 180 190 200 210 880 890 900 910 920 930 pF1KA0 LLNLLLCNHHTLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLLNRYSEPPGSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLNLLLCNHHTLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLLNRYSEPPGSPE 220 230 240 250 260 270 940 950 960 970 980 990 pF1KA0 RAALETPIIQGQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAVRPLLKRLQQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAALETPIIQGQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAVRPLLKRLQQET 280 290 300 310 320 330 1000 1010 1020 1030 1040 1050 pF1KA0 QPFLLLLRTLDAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPFLLLLRTLDAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSE 340 350 360 370 380 390 1060 1070 1080 1090 1100 1110 pF1KA0 IVQELTCFLHRLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCELRDLVTECEKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVQELTCFLHRLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCELRDLVTECEKYA 400 410 420 430 440 450 1120 1130 1140 1150 1160 1170 pF1KA0 QLYSNLTSSILAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSSVEVKEDKCWEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLYSNLTSSILAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSSVEVKEDKCWEK 460 470 480 490 500 510 1180 1190 1200 1210 1220 1230 pF1KA0 VEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSSYMPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSSYMPA 520 530 540 550 560 570 1240 1250 1260 1270 1280 1290 pF1KA0 RVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRCQQGGIDTRVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRCQQGGIDTRVRG 580 590 600 610 620 630 1300 1310 1320 1330 1340 1350 pF1KA0 VEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQN 640 650 660 670 680 690 1360 1370 1380 1390 1400 1410 pF1KA0 FADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQYLEQRETSRNPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQYLEQRETSRNPL 700 710 720 730 740 750 1420 1430 1440 1450 1460 1470 pF1KA0 SRAASFASRVRRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRAASFASRVRRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNI 760 770 780 790 800 810 1480 1490 1500 1510 1520 1530 pF1KA0 TQCWLSVVQEQVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAAFMLALRSGFSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQCWLSVVQEQVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAAFMLALRSGFSG 820 830 840 850 860 870 1540 pF1KA0 ALLQQSFLTAAH------------------------------------------------ :::::::::::: XP_016 ALLQQSFLTAAHVSPTSSPQGYKLVFQVHLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCP 880 890 900 910 920 930 1550 1560 1570 1580 1590 1600 pF1KA0 -MSEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMAD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QMSEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMAD 940 950 960 970 980 990 1610 1620 1630 1640 1650 1660 pF1KA0 RLLSFGSSWLEGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLLSFGSSWLEGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQE 1000 1010 1020 1030 1040 1050 1670 1680 1690 1700 1710 1720 pF1KA0 DEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTE 1060 1070 1080 1090 1100 1110 1730 1740 1750 1760 1770 1780 pF1KA0 FCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFN 1120 1130 1140 1150 1160 1170 1790 1800 1810 1820 1830 1840 pF1KA0 QTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSG 1180 1190 1200 1210 1220 1230 1850 1860 1870 1880 1890 1900 pF1KA0 EALWLIPPQAYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALWLIPPQAYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQK 1240 1250 1260 1270 1280 1290 1910 1920 1930 1940 1950 1960 pF1KA0 GPNPPGTLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPNPPGTLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQ 1300 1310 1320 1330 1340 1350 1970 1980 1990 2000 2010 2020 pF1KA0 ADVPFCGSQSETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADVPFCGSQSETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDV 1360 1370 1380 1390 1400 1410 2030 2040 2050 2060 2070 2080 pF1KA0 AQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDL 1420 1430 1440 1450 1460 1470 2090 2100 2110 2120 2130 2140 pF1KA0 PSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYE 1480 1490 1500 1510 1520 1530 2150 2160 2170 2180 2190 2200 pF1KA0 KALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASC 1540 1550 1560 1570 1580 1590 2210 2220 2230 2240 2250 2260 pF1KA0 GHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCW 1600 1610 1620 1630 1640 1650 2270 2280 2290 2300 2310 2320 pF1KA0 RCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEV 1660 1670 1680 1690 1700 1710 2330 2340 2350 2360 2370 2380 pF1KA0 PPPRSFTFLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPPRSFTFLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILL 1720 1730 1740 1750 1760 1770 2390 2400 2410 2420 2430 2440 pF1KA0 EETLLRCRDLASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EETLLRCRDLASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWE 1780 1790 1800 1810 1820 1830 2450 2460 2470 2480 2490 2500 pF1KA0 AKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETF 1840 1850 1860 1870 1880 1890 2510 pF1KA0 FFGDEEEDEDEAYD :::::::::::::: XP_016 FFGDEEEDEDEAYD 1900 2517 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:27:02 2016 done: Sat Nov 5 13:27:05 2016 Total Scan time: 22.310 Total Display time: 1.760 Function used was FASTA [36.3.4 Apr, 2011]