FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0713, 957 aa 1>>>pF1KA0713 957 - 957 aa - 957 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8730+/-0.00105; mu= 18.5021+/- 0.063 mean_var=78.9245+/-15.751, 0's: 0 Z-trim(103.2): 63 B-trim: 0 in 0/53 Lambda= 0.144367 statistics sampled from 7239 (7294) to 7239 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.224), width: 16 Scan time: 3.010 The best scores are: opt bits E(32554) CCDS47551.1 SNX13 gene_id:23161|Hs108|chr7 ( 957) 6335 1330.0 0 CCDS34116.1 SNX25 gene_id:83891|Hs108|chr4 ( 840) 417 97.4 1.3e-19 >>CCDS47551.1 SNX13 gene_id:23161|Hs108|chr7 (957 aa) initn: 6335 init1: 6335 opt: 6335 Z-score: 7126.3 bits: 1330.0 E(32554): 0 Smith-Waterman score: 6335; 100.0% identity (100.0% similar) in 957 aa overlap (1-957:1-957) 10 20 30 40 50 60 pF1KA0 MLTEASLSIWGWGSLGIVLFLITFGPFVIFYLTFYILCFVGGGLVVTLLFGKTNSEKYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MLTEASLSIWGWGSLGIVLFLITFGPFVIFYLTFYILCFVGGGLVVTLLFGKTNSEKYLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QCEHSFLPPTSPGVPKCLEEMKREARTIKIDRRLTGANIIDEPLQQVIQFSLRDYVQYWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QCEHSFLPPTSPGVPKCLEEMKREARTIKIDRRLTGANIIDEPLQQVIQFSLRDYVQYWY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTRIVDDFGTHLRVFRKAQQKIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 YTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTRIVDDFGTHLRVFRKAQQKIT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EKDDQVKGTAEDLVDTFFEVEVEMEKEVCRDLVCTSPKDEEGFLRDLCEVLLYLLLPPGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 EKDDQVKGTAEDLVDTFFEVEVEMEKEVCRDLVCTSPKDEEGFLRDLCEVLLYLLLPPGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 FQNKIMRYFVREILARGILLPLINQLSDPDYINQYVIWMIRDSNCNYEAFMNIIKLSDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 FQNKIMRYFVREILARGILLPLINQLSDPDYINQYVIWMIRDSNCNYEAFMNIIKLSDNI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GELEAVRDKAAEELQYLRSLDTAGDDINTIKNQINSLLFVKKVCDSRIQRLQSGKEINTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 GELEAVRDKAAEELQYLRSLDTAGDDINTIKNQINSLLFVKKVCDSRIQRLQSGKEINTV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 KLAANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KLAANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LSRQRDGKHQTNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LSRQRDGKHQTNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 IFDDIQRKVYELMLRDERFYPSFRQNALYVRMLAELDMLKDPSFRGSDDGDGESFNGSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 IFDDIQRKVYELMLRDERFYPSFRQNALYVRMLAELDMLKDPSFRGSDDGDGESFNGSPT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 GSINLSLDDLSNVSSDDSVQLHAYISDTGVCNDHGKTYALYAITVHRRNLNSEEMWKTYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 GSINLSLDDLSNVSSDDSVQLHAYISDTGVCNDHGKTYALYAITVHRRNLNSEEMWKTYR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 RYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 ASPALAHYVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGMTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ASPALAHYVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGMTK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 MSDNMGKMSERLGQDIKQSFFKVPPLIPKTDSDPEHRRVSAQLDDNVDDNIPLRVMLLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MSDNMGKMSERLGQDIKQSFFKVPPLIPKTDSDPEHRRVSAQLDDNVDDNIPLRVMLLLM 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 DEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRKIVDHVDWMTSPEQVADSVKRFRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRKIVDHVDWMTSPEQVADSVKRFRDA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 FWPNGILAEAVPCRDKSIRMRTRVAGKTKLLAIMPDELKHIIGAETTRKGILRVFEMFQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 FWPNGILAEAVPCRDKSIRMRTRVAGKTKLLAIMPDELKHIIGAETTRKGILRVFEMFQH 850 860 870 880 890 900 910 920 930 940 950 pF1KA0 NQLNRRMVYVFLEGFLETLFPQYKFRELFNKLHSRSKQMQKYKQKLQTTQAPSLQKR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 NQLNRRMVYVFLEGFLETLFPQYKFRELFNKLHSRSKQMQKYKQKLQTTQAPSLQKR 910 920 930 940 950 >>CCDS34116.1 SNX25 gene_id:83891|Hs108|chr4 (840 aa) initn: 662 init1: 270 opt: 417 Z-score: 465.7 bits: 97.4 E(32554): 1.3e-19 Smith-Waterman score: 695; 25.2% identity (52.1% similar) in 929 aa overlap (100-924:1-829) 70 80 90 100 110 120 pF1KA0 TSPGVPKCLEEMKREARTIKIDRRLTGANIIDEPLQQVIQFSLRDYVQYWYYTLSDDESF .:. :..:...: :::. :: .:: ::. CCDS34 MDKALKEVFDYSYRDYILSWYGNLSRDEGQ 10 20 30 130 140 150 160 170 180 pF1KA0 LLEIR-QTLQNALIQFATRSKEIDWQPYFTTRIVDDFGTHLRVFRKAQQKITEKDDQVKG : .. . . . :. : ...: . .: . ::. .. :. . ...: . CCDS34 LYHLLLEDFWEIARQLHHRLSHVDVVKVVCNDVVRTLLTHFCDLKAANAR---HEEQPRP 40 50 60 70 80 190 200 210 220 230 240 pF1KA0 TAEDLVDTFFEVEVEMEKEVCRDLVCTSPKDEE-GFLRDLCEVLLYLLLPPGDFQNKIMR : ... : .:.: ::. .::.. ::: : :. .: CCDS34 ---------FVLHA-----------CLRNSDDEVRFLQTCSRVLVFCLLPSKDVQSLSLR 90 100 110 120 250 260 270 280 290 pF1KA0 YFVREILARGILLPLINQLSDPDYINQYVIWMI--RDSNC-----------NYEAFMNII .. :::. .: :... ::.::::::... .. :.. .:: :...: CCDS34 IMLAEILTTKVLKPVVELLSNPDYINQMLLAQLAYREQMNEHHKRAYTYAPSYEDFIKLI 130 140 150 160 170 180 300 310 320 330 pF1KA0 KLSDNIGELEAVRDKAAEE------------LQYLRSLDTAG--DDI---NTIKNQINSL . .... :. .: . . : :. .. .::. :. ..: ::.: CCDS34 NSNSDVEFLKQLRYQIVVEIIQATTISSFPQLKRHKGKETAAMKADLLRARNMKRYINQL 190 200 210 220 230 240 340 350 360 370 380 390 pF1KA0 LFVKKVCDSRIQRLQSGKEINTVKLAA-NFGK----LCTVPLDSILVDNVALQFFMDYMQ .:: :..:: :. .: . . .: . :. . ...::... . : ::. CCDS34 TVAKKQCEKRI-RILGGPAYDQQEDGALDEGEGPQSQKILQFEDILANTFYREHFGMYME 250 260 270 280 290 300 400 410 420 430 440 450 pF1KA0 QTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQTNQTKGLLRAAAVGIYEQYLSE . .: . :: .:: : : .:. . . ::.... : CCDS34 RMDKRALISFWESVE---------------------HLKNANKNEIPQLVGEIYQNFFVE 310 320 330 340 460 470 480 490 500 510 pF1KA0 KASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRDERFYPSFRQNALYVRM : ...:. : .. . : . :.: ::. ::: :.: :.:::: . :: .. CCDS34 --SKEISVEKSLYKEIQQCLVGNKGI-EVFYKIQEDVYET-LKD-RYYPSFIVSDLYEKL 350 360 370 380 390 400 520 530 540 pF1KA0 LAELD------MLKDPSFRGSDDGDGESFNGSPTGSIN---------------------L : . . :... . : : :: . :..:: CCDS34 LIKEEEKHASQMISNKDEMGPRDEAGEEAVDDGTNQINEQASFAVNKLRELNEKLEYKRQ 410 420 430 440 450 460 550 560 570 pF1KA0 SLDDLSNVSSDDS-------------------VQLH---------------AYISDTGVC .:....:. . :. .::: : :.. : CCDS34 ALNSIQNAPKPDKKIVSKLKDEIILIEKERTDLQLHMARTDWWCENLGMWKASITSGEVT 470 480 490 500 510 520 580 590 600 610 620 pF1KA0 NDHGKTYALYAITVHRRNLNSEEM--WKTYRRYSDFHDFHMRITEQFESLSSILKLPG-- ...:. : . : ..... : : . :: :.:...: ...: ::... .::. CCDS34 EENGEQLPCYFVMVSLQEVGGVETKNWTVPRRLSEFQNLHRKLSECVPSLKKV-QLPSLS 530 540 550 560 570 630 640 650 660 670 680 pF1KA0 KKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMKASPALAHYVYDFLENKAYSKGKGDFAR : :...:. :.:: :..:: .:: ::. : . : :: : :: . :. . CCDS34 KLPFKSIDQKFMEKSKNQLNKFLQNLLSDERLCQSEAL----YAFLSPSP------DYLK 580 590 600 610 620 690 700 710 720 730 740 pF1KA0 KMDTFVNPLRNSMRNVSNAVKSLPDSLAEGMTKMSDNMGKMSERLGQDIKQSFFKVPPLI .: :. .::. :: . : ::: .: ::. CCDS34 VID--VQGKKNSF--------SLSSFL---------------ERLPRD----FFSHQEEE 630 640 650 660 750 760 770 780 790 800 pF1KA0 PKTDSDPEHRRVSAQLDDNVDD--NIPLRVMLLLMDEVFDLKERNQWLRRNIKNLLQQLI . ::: .. :.:: . . ..:. :.:.:. .:.::. : :. CCDS34 TEEDSD------LSDYGDDVDGRKDALAEPCFMLIGEIFELRGMFKWVRRT----LIALV 670 680 690 700 710 810 820 830 840 850 860 pF1KA0 RATYGDTINRKIVDHVDWMTSPEQVADSVKRFRDAFWPNGILAEAVPCRDKSIRMRTRVA ..:.: :::..: : :.:. : .... .. ::::::::: :: . :.: ..:. CCDS34 QVTFGRTINKQIRDTVSWIFSEQMLVYYINIFRDAFWPNGKLAPPTTIRSKEQSQETKQR 720 730 740 750 760 770 870 880 890 900 910 920 pF1KA0 GKTKLLAIMPDELKHIIGAETTRKGILRVFEMFQHNQLNRRMVYVFLEGFLETLFPQYKF .. ::: .:: :. ..: ...:.::...:. .:... :....:...: .: : :. . CCDS34 AQQKLLENIPDMLQSLVGQQNARHGIIKIFNALQETRANKHLLYALMELLLIELCPELRV 780 790 800 810 820 830 930 940 950 pF1KA0 RELFNKLHSRSKQMQKYKQKLQTTQAPSLQKR CCDS34 HLDQLKAGQV 840 957 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:34:20 2016 done: Wed Nov 2 19:34:20 2016 Total Scan time: 3.010 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]