FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0714, 1766 aa 1>>>pF1KA0714 1766 - 1766 aa - 1766 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7697+/-0.000532; mu= 22.2080+/- 0.033 mean_var=84.3454+/-16.882, 0's: 0 Z-trim(107.5): 109 B-trim: 917 in 2/51 Lambda= 0.139651 statistics sampled from 15461 (15552) to 15461 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.522), E-opt: 0.2 (0.182), width: 16 Scan time: 16.240 The best scores are: opt bits E(85289) NP_056380 (OMIM: 613083) E3 ubiquitin-protein liga (1812) 11602 2349.2 0 XP_016883805 (OMIM: 613083) PREDICTED: E3 ubiquiti (1477) 9688 1963.5 0 NP_001307695 (OMIM: 613083) E3 ubiquitin-protein l (1798) 6924 1406.7 0 XP_016883806 (OMIM: 613083) PREDICTED: E3 ubiquiti (1055) 6907 1403.1 0 XP_006724050 (OMIM: 613083) PREDICTED: E3 ubiquiti ( 925) 5636 1147.0 0 >>NP_056380 (OMIM: 613083) E3 ubiquitin-protein ligase l (1812 aa) initn: 11602 init1: 11602 opt: 11602 Z-score: 12624.8 bits: 2349.2 E(85289): 0 Smith-Waterman score: 11602; 99.9% identity (99.9% similar) in 1766 aa overlap (1-1766:47-1812) 10 20 30 pF1KA0 MGGKNKQRTKGNLRPSNSGRAAELLAKEQG :::::::::::::::::::::::::::::: NP_056 VSSSAARSRKLCPGRVNRGLSAQSTAATATMGGKNKQRTKGNLRPSNSGRAAELLAKEQG 20 30 40 50 60 70 40 50 60 70 80 90 pF1KA0 TVPGFIGFGTSQSDLGYVPAIQGAEEIDSLVDSDFRMVLRKLSKKDVTTKLKAMQEFGTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TVPGFIGFGTSQSDLGYVPAIQGAEEIDSLVDSDFRMVLRKLSKKDVTTKLKAMQEFGTM 80 90 100 110 120 130 100 110 120 130 140 150 pF1KA0 CTERDTETVKGVLPYWPRIFCKISLDHDRRVREATQQAFEKLILKVKKQLAPYLKSLMGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 CTERDTETVKGVLPYWPRIFCKISLDHDRRVREATQQAFEKLILKVKKQLAPYLKSLMGY 140 150 160 170 180 190 160 170 180 190 200 210 pF1KA0 WLMAQCDTYTPAAFAAKDAFEAAFPPSKQPEAIAFCKDEITSVLQDHLIKETPDTLSDPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 WLMAQCDTYTPAAFAAKDAFEAAFPPSKQPEAIAFCKDEITSVLQDHLIKETPDTLSDPQ 200 210 220 230 240 250 220 230 240 250 260 270 pF1KA0 TVPEEEREAKFYRVVTCSLLALKRLLCLLPDNELDSLEEKFKSLLSQNKFWKYGKHSVPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TVPEEEREAKFYRVVTCSLLALKRLLCLLPDNELDSLEEKFKSLLSQNKFWKYGKHSVPQ 260 270 280 290 300 310 280 290 300 310 320 330 pF1KA0 IRSAYFELVSALCQRIPQLMKEEASKVSPSVLLSIDDSDPIVCPALWEAVLYTLTTIEDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IRSAYFELVSALCQRIPQLMKEEASKVSPSVLLSIDDSDPIVCPALWEAVLYTLTTIEDC 320 330 340 350 360 370 340 350 360 370 380 390 pF1KA0 WLHVNAKKSVFPKLSTVIREGGRGLATVIYPYLLPFISKLPQSITNPKLDFFKNFLTSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 WLHVNAKKSVFPKLSTVIREGGRGLATVIYPYLLPFISKLPQSITNPKLDFFKNFLTSLV 380 390 400 410 420 430 400 410 420 430 440 450 pF1KA0 AGLSTERTKTSSSESSAVISAFFECLRFIMQQNLGEEEIEQMLVNDQLIPFIDAVLKDPG :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AGLSTERTKTSSLESSAVISAFFECLRFIMQQNLGEEEIEQMLVNDQLIPFIDAVLKDPG 440 450 460 470 480 490 460 470 480 490 500 510 pF1KA0 LQHGQLFNHLAETLSSWEAKADTEKDEKTAHNLENVLIHFWERLSEICVAKISEPEADVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LQHGQLFNHLAETLSSWEAKADTEKDEKTAHNLENVLIHFWERLSEICVAKISEPEADVE 500 510 520 530 540 550 520 530 540 550 560 570 pF1KA0 SVLGVSNLLQVLQKPKSSLKSSKKKNGKVRFADEILESNKENEKCVSSEGEKIEGWELTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SVLGVSNLLQVLQKPKSSLKSSKKKNGKVRFADEILESNKENEKCVSSEGEKIEGWELTT 560 570 580 590 600 610 580 590 600 610 620 630 pF1KA0 EPSLTHNSSGLLSPLRKKPLEDLVCKLADISINYVNERKSEQHLRFLSTLLDSFSSSRVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EPSLTHNSSGLLSPLRKKPLEDLVCKLADISINYVNERKSEQHLRFLSTLLDSFSSSRVF 620 630 640 650 660 670 640 650 660 670 680 690 pF1KA0 KMLLGDEKQSIVQAKPLEIAKLVQKNPAVQFLYQKLIGWLNEDQRKDFGFLVDILYSALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KMLLGDEKQSIVQAKPLEIAKLVQKNPAVQFLYQKLIGWLNEDQRKDFGFLVDILYSALR 680 690 700 710 720 730 700 710 720 730 740 750 pF1KA0 CCDNDMERKKVLDDLTKVDLKWNSLLKIIEKACPSSDKHALVTPWLKGDILGEKLVNLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 CCDNDMERKKVLDDLTKVDLKWNSLLKIIEKACPSSDKHALVTPWLKGDILGEKLVNLAD 740 750 760 770 780 790 760 770 780 790 800 810 pF1KA0 CLCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVRLHETLFKTKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 CLCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVRLHETLFKTKKL 800 810 820 830 840 850 820 830 840 850 860 870 pF1KA0 SEAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKEKTHLPDFLICK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SEAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKEKTHLPDFLICK 860 870 880 890 900 910 880 890 900 910 920 930 pF1KA0 LKNTWLSGVNLLVHQTDSSYKESTFLHLSALWLKNQVQASSLDINSLQVLLSAVDDLLNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LKNTWLSGVNLLVHQTDSSYKESTFLHLSALWLKNQVQASSLDINSLQVLLSAVDDLLNT 920 930 940 950 960 970 940 950 960 970 980 990 pF1KA0 LLESEDSYLMGVYIGSVMPNDSEWEKMRQSLPMQWLHRPLLEGRLSLNYECFKTDFKEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LLESEDSYLMGVYIGSVMPNDSEWEKMRQSLPMQWLHRPLLEGRLSLNYECFKTDFKEQD 980 990 1000 1010 1020 1030 1000 1010 1020 1030 1040 1050 pF1KA0 IKTLPSHLCTSALLSKMVLIALRKETVLENNELEKIIAELLYSLQWCEELDNPPIFLIGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IKTLPSHLCTSALLSKMVLIALRKETVLENNELEKIIAELLYSLQWCEELDNPPIFLIGF 1040 1050 1060 1070 1080 1090 1060 1070 1080 1090 1100 1110 pF1KA0 CEILQKMNITYDNLRVLGNTSGLLQLLFNRSREHGTLWSLIIAKLILSRSISSDEVKPHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 CEILQKMNITYDNLRVLGNTSGLLQLLFNRSREHGTLWSLIIAKLILSRSISSDEVKPHY 1100 1110 1120 1130 1140 1150 1120 1130 1140 1150 1160 1170 pF1KA0 KRKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQCIPALLGWTKKDLCSTNGGFGHLAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KRKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQCIPALLGWTKKDLCSTNGGFGHLAI 1160 1170 1180 1190 1200 1210 1180 1190 1200 1210 1220 1230 pF1KA0 FNSCLQTKSIDDGELLHGILKIIISWKKEHEDIFLFSCNLSEASPEVLGVNIEIIRFLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FNSCLQTKSIDDGELLHGILKIIISWKKEHEDIFLFSCNLSEASPEVLGVNIEIIRFLSL 1220 1230 1240 1250 1260 1270 1240 1250 1260 1270 1280 1290 pF1KA0 FLKYCSSPLAESEWDFIMCSMLAWLETTSENQALYSIPLVQLFACVSCDLACDLSAFFDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FLKYCSSPLAESEWDFIMCSMLAWLETTSENQALYSIPLVQLFACVSCDLACDLSAFFDS 1280 1290 1300 1310 1320 1330 1300 1310 1320 1330 1340 1350 pF1KA0 TTLDTIGNLPVNLISEWKEFFSQGIHSLLLPILVTVTGENKDVSETSFQNAMLKPMCETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TTLDTIGNLPVNLISEWKEFFSQGIHSLLLPILVTVTGENKDVSETSFQNAMLKPMCETL 1340 1350 1360 1370 1380 1390 1360 1370 1380 1390 1400 1410 pF1KA0 TYISKEQLLSHKLPARLVADQKTNLPEYLQTLLNTLAPLLLFRARPVQIAVYHMLYKLMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TYISKEQLLSHKLPARLVADQKTNLPEYLQTLLNTLAPLLLFRARPVQIAVYHMLYKLMP 1400 1410 1420 1430 1440 1450 1420 1430 1440 1450 1460 1470 pF1KA0 ELPQYDQDNLKSYGDEEEEPALSPPAALMSLLSIQEDLLENVLGCIPVGQIVTIKPLSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ELPQYDQDNLKSYGDEEEEPALSPPAALMSLLSIQEDLLENVLGCIPVGQIVTIKPLSED 1460 1470 1480 1490 1500 1510 1480 1490 1500 1510 1520 1530 pF1KA0 FCYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRLMPENPTYAETA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FCYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRLMPENPTYAETA 1520 1530 1540 1550 1560 1570 1540 1550 1560 1570 1580 1590 pF1KA0 VEVPNKDPKTFFTEELQLSIRETTMLPYHIPHLACSVYHMTLKDLPAMVRLWWNSSEKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VEVPNKDPKTFFTEELQLSIRETTMLPYHIPHLACSVYHMTLKDLPAMVRLWWNSSEKRV 1580 1590 1600 1610 1620 1630 1600 1610 1620 1630 1640 1650 pF1KA0 FNIVDRFTSKYVSSVLSFQEISSVQTSTQLFNGMTVKARATTREVMATYTIEDIVIELII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FNIVDRFTSKYVSSVLSFQEISSVQTSTQLFNGMTVKARATTREVMATYTIEDIVIELII 1640 1650 1660 1670 1680 1690 1660 1670 1680 1690 1700 1710 pF1KA0 QLPSNYPLGSIIVESGKRVGVAVQQWRNWMLQLSTYLTHQNGSIMEGLALWKNNVDKRFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QLPSNYPLGSIIVESGKRVGVAVQQWRNWMLQLSTYLTHQNGSIMEGLALWKNNVDKRFE 1700 1710 1720 1730 1740 1750 1720 1730 1740 1750 1760 pF1KA0 GVEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GVEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF 1760 1770 1780 1790 1800 1810 >>XP_016883805 (OMIM: 613083) PREDICTED: E3 ubiquitin-pr (1477 aa) initn: 9688 init1: 9688 opt: 9688 Z-score: 10542.1 bits: 1963.5 E(85289): 0 Smith-Waterman score: 9688; 99.9% identity (99.9% similar) in 1477 aa overlap (290-1766:1-1477) 260 270 280 290 300 310 pF1KA0 FWKYGKHSVPQIRSAYFELVSALCQRIPQLMKEEASKVSPSVLLSIDDSDPIVCPALWEA :::::::::::::::::::::::::::::: XP_016 MKEEASKVSPSVLLSIDDSDPIVCPALWEA 10 20 30 320 330 340 350 360 370 pF1KA0 VLYTLTTIEDCWLHVNAKKSVFPKLSTVIREGGRGLATVIYPYLLPFISKLPQSITNPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLYTLTTIEDCWLHVNAKKSVFPKLSTVIREGGRGLATVIYPYLLPFISKLPQSITNPKL 40 50 60 70 80 90 380 390 400 410 420 430 pF1KA0 DFFKNFLTSLVAGLSTERTKTSSSESSAVISAFFECLRFIMQQNLGEEEIEQMLVNDQLI ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_016 DFFKNFLTSLVAGLSTERTKTSSLESSAVISAFFECLRFIMQQNLGEEEIEQMLVNDQLI 100 110 120 130 140 150 440 450 460 470 480 490 pF1KA0 PFIDAVLKDPGLQHGQLFNHLAETLSSWEAKADTEKDEKTAHNLENVLIHFWERLSEICV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFIDAVLKDPGLQHGQLFNHLAETLSSWEAKADTEKDEKTAHNLENVLIHFWERLSEICV 160 170 180 190 200 210 500 510 520 530 540 550 pF1KA0 AKISEPEADVESVLGVSNLLQVLQKPKSSLKSSKKKNGKVRFADEILESNKENEKCVSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKISEPEADVESVLGVSNLLQVLQKPKSSLKSSKKKNGKVRFADEILESNKENEKCVSSE 220 230 240 250 260 270 560 570 580 590 600 610 pF1KA0 GEKIEGWELTTEPSLTHNSSGLLSPLRKKPLEDLVCKLADISINYVNERKSEQHLRFLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEKIEGWELTTEPSLTHNSSGLLSPLRKKPLEDLVCKLADISINYVNERKSEQHLRFLST 280 290 300 310 320 330 620 630 640 650 660 670 pF1KA0 LLDSFSSSRVFKMLLGDEKQSIVQAKPLEIAKLVQKNPAVQFLYQKLIGWLNEDQRKDFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLDSFSSSRVFKMLLGDEKQSIVQAKPLEIAKLVQKNPAVQFLYQKLIGWLNEDQRKDFG 340 350 360 370 380 390 680 690 700 710 720 730 pF1KA0 FLVDILYSALRCCDNDMERKKVLDDLTKVDLKWNSLLKIIEKACPSSDKHALVTPWLKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLVDILYSALRCCDNDMERKKVLDDLTKVDLKWNSLLKIIEKACPSSDKHALVTPWLKGD 400 410 420 430 440 450 740 750 760 770 780 790 pF1KA0 ILGEKLVNLADCLCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILGEKLVNLADCLCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVR 460 470 480 490 500 510 800 810 820 830 840 850 pF1KA0 LHETLFKTKKLSEAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHETLFKTKKLSEAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKE 520 530 540 550 560 570 860 870 880 890 900 910 pF1KA0 KTHLPDFLICKLKNTWLSGVNLLVHQTDSSYKESTFLHLSALWLKNQVQASSLDINSLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTHLPDFLICKLKNTWLSGVNLLVHQTDSSYKESTFLHLSALWLKNQVQASSLDINSLQV 580 590 600 610 620 630 920 930 940 950 960 970 pF1KA0 LLSAVDDLLNTLLESEDSYLMGVYIGSVMPNDSEWEKMRQSLPMQWLHRPLLEGRLSLNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLSAVDDLLNTLLESEDSYLMGVYIGSVMPNDSEWEKMRQSLPMQWLHRPLLEGRLSLNY 640 650 660 670 680 690 980 990 1000 1010 1020 1030 pF1KA0 ECFKTDFKEQDIKTLPSHLCTSALLSKMVLIALRKETVLENNELEKIIAELLYSLQWCEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ECFKTDFKEQDIKTLPSHLCTSALLSKMVLIALRKETVLENNELEKIIAELLYSLQWCEE 700 710 720 730 740 750 1040 1050 1060 1070 1080 1090 pF1KA0 LDNPPIFLIGFCEILQKMNITYDNLRVLGNTSGLLQLLFNRSREHGTLWSLIIAKLILSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDNPPIFLIGFCEILQKMNITYDNLRVLGNTSGLLQLLFNRSREHGTLWSLIIAKLILSR 760 770 780 790 800 810 1100 1110 1120 1130 1140 1150 pF1KA0 SISSDEVKPHYKRKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQCIPALLGWTKKDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SISSDEVKPHYKRKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQCIPALLGWTKKDLC 820 830 840 850 860 870 1160 1170 1180 1190 1200 1210 pF1KA0 STNGGFGHLAIFNSCLQTKSIDDGELLHGILKIIISWKKEHEDIFLFSCNLSEASPEVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STNGGFGHLAIFNSCLQTKSIDDGELLHGILKIIISWKKEHEDIFLFSCNLSEASPEVLG 880 890 900 910 920 930 1220 1230 1240 1250 1260 1270 pF1KA0 VNIEIIRFLSLFLKYCSSPLAESEWDFIMCSMLAWLETTSENQALYSIPLVQLFACVSCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNIEIIRFLSLFLKYCSSPLAESEWDFIMCSMLAWLETTSENQALYSIPLVQLFACVSCD 940 950 960 970 980 990 1280 1290 1300 1310 1320 1330 pF1KA0 LACDLSAFFDSTTLDTIGNLPVNLISEWKEFFSQGIHSLLLPILVTVTGENKDVSETSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LACDLSAFFDSTTLDTIGNLPVNLISEWKEFFSQGIHSLLLPILVTVTGENKDVSETSFQ 1000 1010 1020 1030 1040 1050 1340 1350 1360 1370 1380 1390 pF1KA0 NAMLKPMCETLTYISKEQLLSHKLPARLVADQKTNLPEYLQTLLNTLAPLLLFRARPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAMLKPMCETLTYISKEQLLSHKLPARLVADQKTNLPEYLQTLLNTLAPLLLFRARPVQI 1060 1070 1080 1090 1100 1110 1400 1410 1420 1430 1440 1450 pF1KA0 AVYHMLYKLMPELPQYDQDNLKSYGDEEEEPALSPPAALMSLLSIQEDLLENVLGCIPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVYHMLYKLMPELPQYDQDNLKSYGDEEEEPALSPPAALMSLLSIQEDLLENVLGCIPVG 1120 1130 1140 1150 1160 1170 1460 1470 1480 1490 1500 1510 pF1KA0 QIVTIKPLSEDFCYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIVTIKPLSEDFCYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRL 1180 1190 1200 1210 1220 1230 1520 1530 1540 1550 1560 1570 pF1KA0 MPENPTYAETAVEVPNKDPKTFFTEELQLSIRETTMLPYHIPHLACSVYHMTLKDLPAMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPENPTYAETAVEVPNKDPKTFFTEELQLSIRETTMLPYHIPHLACSVYHMTLKDLPAMV 1240 1250 1260 1270 1280 1290 1580 1590 1600 1610 1620 1630 pF1KA0 RLWWNSSEKRVFNIVDRFTSKYVSSVLSFQEISSVQTSTQLFNGMTVKARATTREVMATY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLWWNSSEKRVFNIVDRFTSKYVSSVLSFQEISSVQTSTQLFNGMTVKARATTREVMATY 1300 1310 1320 1330 1340 1350 1640 1650 1660 1670 1680 1690 pF1KA0 TIEDIVIELIIQLPSNYPLGSIIVESGKRVGVAVQQWRNWMLQLSTYLTHQNGSIMEGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIEDIVIELIIQLPSNYPLGSIIVESGKRVGVAVQQWRNWMLQLSTYLTHQNGSIMEGLA 1360 1370 1380 1390 1400 1410 1700 1710 1720 1730 1740 1750 pF1KA0 LWKNNVDKRFEGVEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWKNNVDKRFEGVEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCP 1420 1430 1440 1450 1460 1470 1760 pF1KA0 LCRETFF ::::::: XP_016 LCRETFF >>NP_001307695 (OMIM: 613083) E3 ubiquitin-protein ligas (1798 aa) initn: 6914 init1: 6914 opt: 6924 Z-score: 7531.2 bits: 1406.7 E(85289): 0 Smith-Waterman score: 11475; 99.2% identity (99.2% similar) in 1766 aa overlap (1-1766:47-1798) 10 20 30 pF1KA0 MGGKNKQRTKGNLRPSNSGRAAELLAKEQG :::::::::::::::::::::::::::::: NP_001 VSSSAARSRKLCPGRVNRGLSAQSTAATATMGGKNKQRTKGNLRPSNSGRAAELLAKEQG 20 30 40 50 60 70 40 50 60 70 80 90 pF1KA0 TVPGFIGFGTSQSDLGYVPAIQGAEEIDSLVDSDFRMVLRKLSKKDVTTKLKAMQEFGTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVPGFIGFGTSQSDLGYVPAIQGAEEIDSLVDSDFRMVLRKLSKKDVTTKLKAMQEFGTM 80 90 100 110 120 130 100 110 120 130 140 150 pF1KA0 CTERDTETVKGVLPYWPRIFCKISLDHDRRVREATQQAFEKLILKVKKQLAPYLKSLMGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CTERDTETVKGVLPYWPRIFCKISLDHDRRVREATQQAFEKLILKVKKQLAPYLKSLMGY 140 150 160 170 180 190 160 170 180 190 200 210 pF1KA0 WLMAQCDTYTPAAFAAKDAFEAAFPPSKQPEAIAFCKDEITSVLQDHLIKETPDTLSDPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WLMAQCDTYTPAAFAAKDAFEAAFPPSKQPEAIAFCKDEITSVLQDHLIKETPDTLSDPQ 200 210 220 230 240 250 220 230 240 250 260 270 pF1KA0 TVPEEEREAKFYRVVTCSLLALKRLLCLLPDNELDSLEEKFKSLLSQNKFWKYGKHSVPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVPEEEREAKFYRVVTCSLLALKRLLCLLPDNELDSLEEKFKSLLSQNKFWKYGKHSVPQ 260 270 280 290 300 310 280 290 300 310 320 330 pF1KA0 IRSAYFELVSALCQRIPQLMKEEASKVSPSVLLSIDDSDPIVCPALWEAVLYTLTTIEDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRSAYFELVSALCQRIPQLMKEEASKVSPSVLLSIDDSDPIVCPALWEAVLYTLTTIEDC 320 330 340 350 360 370 340 350 360 370 380 390 pF1KA0 WLHVNAKKSVFPKLSTVIREGGRGLATVIYPYLLPFISKLPQSITNPKLDFFKNFLTSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WLHVNAKKSVFPKLSTVIREGGRGLATVIYPYLLPFISKLPQSITNPKLDFFKNFLTSLV 380 390 400 410 420 430 400 410 420 430 440 450 pF1KA0 AGLSTERTKTSSSESSAVISAFFECLRFIMQQNLGEEEIEQMLVNDQLIPFIDAVLKDPG :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGLSTERTKTSSLESSAVISAFFECLRFIMQQNLGEEEIEQMLVNDQLIPFIDAVLKDPG 440 450 460 470 480 490 460 470 480 490 500 510 pF1KA0 LQHGQLFNHLAETLSSWEAKADTEKDEKTAHNLENVLIHFWERLSEICVAKISEPEADVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQHGQLFNHLAETLSSWEAKADTEKDEKTAHNLENVLIHFWERLSEICVAKISEPEADVE 500 510 520 530 540 550 520 530 540 550 560 570 pF1KA0 SVLGVSNLLQVLQKPKSSLKSSKKKNGKVRFADEILESNKENEKCVSSEGEKIEGWELTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVLGVSNLLQVLQKPKSSLKSSKKKNGKVRFADEILESNKENEKCVSSEGEKIEGWELTT 560 570 580 590 600 610 580 590 600 610 620 630 pF1KA0 EPSLTHNSSGLLSPLRKKPLEDLVCKLADISINYVNERKSEQHLRFLSTLLDSFSSSRVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPSLTHNSSGLLSPLRKKPLEDLVCKLADISINYVNERKSEQHLRFLSTLLDSFSSSRVF 620 630 640 650 660 670 640 650 660 670 680 690 pF1KA0 KMLLGDEKQSIVQAKPLEIAKLVQKNPAVQFLYQKLIGWLNEDQRKDFGFLVDILYSALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMLLGDEKQSIVQAKPLEIAKLVQKNPAVQFLYQKLIGWLNEDQRKDFGFLVDILYSALR 680 690 700 710 720 730 700 710 720 730 740 750 pF1KA0 CCDNDMERKKVLDDLTKVDLKWNSLLKIIEKACPSSDKHALVTPWLKGDILGEKLVNLAD ::::::::::::::::: ::::::::::::::::::::::::::::: NP_001 CCDNDMERKKVLDDLTK--------------ACPSSDKHALVTPWLKGDILGEKLVNLAD 740 750 760 770 780 760 770 780 790 800 810 pF1KA0 CLCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVRLHETLFKTKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVRLHETLFKTKKL 790 800 810 820 830 840 820 830 840 850 860 870 pF1KA0 SEAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKEKTHLPDFLICK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKEKTHLPDFLICK 850 860 870 880 890 900 880 890 900 910 920 930 pF1KA0 LKNTWLSGVNLLVHQTDSSYKESTFLHLSALWLKNQVQASSLDINSLQVLLSAVDDLLNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKNTWLSGVNLLVHQTDSSYKESTFLHLSALWLKNQVQASSLDINSLQVLLSAVDDLLNT 910 920 930 940 950 960 940 950 960 970 980 990 pF1KA0 LLESEDSYLMGVYIGSVMPNDSEWEKMRQSLPMQWLHRPLLEGRLSLNYECFKTDFKEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLESEDSYLMGVYIGSVMPNDSEWEKMRQSLPMQWLHRPLLEGRLSLNYECFKTDFKEQD 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KA0 IKTLPSHLCTSALLSKMVLIALRKETVLENNELEKIIAELLYSLQWCEELDNPPIFLIGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKTLPSHLCTSALLSKMVLIALRKETVLENNELEKIIAELLYSLQWCEELDNPPIFLIGF 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KA0 CEILQKMNITYDNLRVLGNTSGLLQLLFNRSREHGTLWSLIIAKLILSRSISSDEVKPHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CEILQKMNITYDNLRVLGNTSGLLQLLFNRSREHGTLWSLIIAKLILSRSISSDEVKPHY 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KA0 KRKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQCIPALLGWTKKDLCSTNGGFGHLAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQCIPALLGWTKKDLCSTNGGFGHLAI 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KA0 FNSCLQTKSIDDGELLHGILKIIISWKKEHEDIFLFSCNLSEASPEVLGVNIEIIRFLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNSCLQTKSIDDGELLHGILKIIISWKKEHEDIFLFSCNLSEASPEVLGVNIEIIRFLSL 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KA0 FLKYCSSPLAESEWDFIMCSMLAWLETTSENQALYSIPLVQLFACVSCDLACDLSAFFDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLKYCSSPLAESEWDFIMCSMLAWLETTSENQALYSIPLVQLFACVSCDLACDLSAFFDS 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 1350 pF1KA0 TTLDTIGNLPVNLISEWKEFFSQGIHSLLLPILVTVTGENKDVSETSFQNAMLKPMCETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTLDTIGNLPVNLISEWKEFFSQGIHSLLLPILVTVTGENKDVSETSFQNAMLKPMCETL 1330 1340 1350 1360 1370 1380 1360 1370 1380 1390 1400 1410 pF1KA0 TYISKEQLLSHKLPARLVADQKTNLPEYLQTLLNTLAPLLLFRARPVQIAVYHMLYKLMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TYISKEQLLSHKLPARLVADQKTNLPEYLQTLLNTLAPLLLFRARPVQIAVYHMLYKLMP 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KA0 ELPQYDQDNLKSYGDEEEEPALSPPAALMSLLSIQEDLLENVLGCIPVGQIVTIKPLSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELPQYDQDNLKSYGDEEEEPALSPPAALMSLLSIQEDLLENVLGCIPVGQIVTIKPLSED 1450 1460 1470 1480 1490 1500 1480 1490 1500 1510 1520 1530 pF1KA0 FCYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRLMPENPTYAETA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FCYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRLMPENPTYAETA 1510 1520 1530 1540 1550 1560 1540 1550 1560 1570 1580 1590 pF1KA0 VEVPNKDPKTFFTEELQLSIRETTMLPYHIPHLACSVYHMTLKDLPAMVRLWWNSSEKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEVPNKDPKTFFTEELQLSIRETTMLPYHIPHLACSVYHMTLKDLPAMVRLWWNSSEKRV 1570 1580 1590 1600 1610 1620 1600 1610 1620 1630 1640 1650 pF1KA0 FNIVDRFTSKYVSSVLSFQEISSVQTSTQLFNGMTVKARATTREVMATYTIEDIVIELII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNIVDRFTSKYVSSVLSFQEISSVQTSTQLFNGMTVKARATTREVMATYTIEDIVIELII 1630 1640 1650 1660 1670 1680 1660 1670 1680 1690 1700 1710 pF1KA0 QLPSNYPLGSIIVESGKRVGVAVQQWRNWMLQLSTYLTHQNGSIMEGLALWKNNVDKRFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLPSNYPLGSIIVESGKRVGVAVQQWRNWMLQLSTYLTHQNGSIMEGLALWKNNVDKRFE 1690 1700 1710 1720 1730 1740 1720 1730 1740 1750 1760 pF1KA0 GVEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF 1750 1760 1770 1780 1790 >>XP_016883806 (OMIM: 613083) PREDICTED: E3 ubiquitin-pr (1055 aa) initn: 6907 init1: 6907 opt: 6907 Z-score: 7516.1 bits: 1403.1 E(85289): 0 Smith-Waterman score: 6907; 100.0% identity (100.0% similar) in 1045 aa overlap (722-1766:11-1055) 700 710 720 730 740 750 pF1KA0 CDNDMERKKVLDDLTKVDLKWNSLLKIIEKACPSSDKHALVTPWLKGDILGEKLVNLADC :::::::::::::::::::::::::::::: XP_016 MFILAYLRDIACPSSDKHALVTPWLKGDILGEKLVNLADC 10 20 30 40 760 770 780 790 800 810 pF1KA0 LCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVRLHETLFKTKKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVRLHETLFKTKKLS 50 60 70 80 90 100 820 830 840 850 860 870 pF1KA0 EAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKEKTHLPDFLICKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKEKTHLPDFLICKL 110 120 130 140 150 160 880 890 900 910 920 930 pF1KA0 KNTWLSGVNLLVHQTDSSYKESTFLHLSALWLKNQVQASSLDINSLQVLLSAVDDLLNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNTWLSGVNLLVHQTDSSYKESTFLHLSALWLKNQVQASSLDINSLQVLLSAVDDLLNTL 170 180 190 200 210 220 940 950 960 970 980 990 pF1KA0 LESEDSYLMGVYIGSVMPNDSEWEKMRQSLPMQWLHRPLLEGRLSLNYECFKTDFKEQDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LESEDSYLMGVYIGSVMPNDSEWEKMRQSLPMQWLHRPLLEGRLSLNYECFKTDFKEQDI 230 240 250 260 270 280 1000 1010 1020 1030 1040 1050 pF1KA0 KTLPSHLCTSALLSKMVLIALRKETVLENNELEKIIAELLYSLQWCEELDNPPIFLIGFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTLPSHLCTSALLSKMVLIALRKETVLENNELEKIIAELLYSLQWCEELDNPPIFLIGFC 290 300 310 320 330 340 1060 1070 1080 1090 1100 1110 pF1KA0 EILQKMNITYDNLRVLGNTSGLLQLLFNRSREHGTLWSLIIAKLILSRSISSDEVKPHYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EILQKMNITYDNLRVLGNTSGLLQLLFNRSREHGTLWSLIIAKLILSRSISSDEVKPHYK 350 360 370 380 390 400 1120 1130 1140 1150 1160 1170 pF1KA0 RKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQCIPALLGWTKKDLCSTNGGFGHLAIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQCIPALLGWTKKDLCSTNGGFGHLAIF 410 420 430 440 450 460 1180 1190 1200 1210 1220 1230 pF1KA0 NSCLQTKSIDDGELLHGILKIIISWKKEHEDIFLFSCNLSEASPEVLGVNIEIIRFLSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSCLQTKSIDDGELLHGILKIIISWKKEHEDIFLFSCNLSEASPEVLGVNIEIIRFLSLF 470 480 490 500 510 520 1240 1250 1260 1270 1280 1290 pF1KA0 LKYCSSPLAESEWDFIMCSMLAWLETTSENQALYSIPLVQLFACVSCDLACDLSAFFDST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKYCSSPLAESEWDFIMCSMLAWLETTSENQALYSIPLVQLFACVSCDLACDLSAFFDST 530 540 550 560 570 580 1300 1310 1320 1330 1340 1350 pF1KA0 TLDTIGNLPVNLISEWKEFFSQGIHSLLLPILVTVTGENKDVSETSFQNAMLKPMCETLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLDTIGNLPVNLISEWKEFFSQGIHSLLLPILVTVTGENKDVSETSFQNAMLKPMCETLT 590 600 610 620 630 640 1360 1370 1380 1390 1400 1410 pF1KA0 YISKEQLLSHKLPARLVADQKTNLPEYLQTLLNTLAPLLLFRARPVQIAVYHMLYKLMPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YISKEQLLSHKLPARLVADQKTNLPEYLQTLLNTLAPLLLFRARPVQIAVYHMLYKLMPE 650 660 670 680 690 700 1420 1430 1440 1450 1460 1470 pF1KA0 LPQYDQDNLKSYGDEEEEPALSPPAALMSLLSIQEDLLENVLGCIPVGQIVTIKPLSEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPQYDQDNLKSYGDEEEEPALSPPAALMSLLSIQEDLLENVLGCIPVGQIVTIKPLSEDF 710 720 730 740 750 760 1480 1490 1500 1510 1520 1530 pF1KA0 CYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRLMPENPTYAETAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRLMPENPTYAETAV 770 780 790 800 810 820 1540 1550 1560 1570 1580 1590 pF1KA0 EVPNKDPKTFFTEELQLSIRETTMLPYHIPHLACSVYHMTLKDLPAMVRLWWNSSEKRVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVPNKDPKTFFTEELQLSIRETTMLPYHIPHLACSVYHMTLKDLPAMVRLWWNSSEKRVF 830 840 850 860 870 880 1600 1610 1620 1630 1640 1650 pF1KA0 NIVDRFTSKYVSSVLSFQEISSVQTSTQLFNGMTVKARATTREVMATYTIEDIVIELIIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIVDRFTSKYVSSVLSFQEISSVQTSTQLFNGMTVKARATTREVMATYTIEDIVIELIIQ 890 900 910 920 930 940 1660 1670 1680 1690 1700 1710 pF1KA0 LPSNYPLGSIIVESGKRVGVAVQQWRNWMLQLSTYLTHQNGSIMEGLALWKNNVDKRFEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPSNYPLGSIIVESGKRVGVAVQQWRNWMLQLSTYLTHQNGSIMEGLALWKNNVDKRFEG 950 960 970 980 990 1000 1720 1730 1740 1750 1760 pF1KA0 VEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF 1010 1020 1030 1040 1050 >>XP_006724050 (OMIM: 613083) PREDICTED: E3 ubiquitin-pr (925 aa) initn: 5634 init1: 5634 opt: 5636 Z-score: 6133.0 bits: 1147.0 E(85289): 0 Smith-Waterman score: 5636; 98.6% identity (98.9% similar) in 879 aa overlap (1-876:47-925) 10 20 30 pF1KA0 MGGKNKQRTKGNLRPSNSGRAAELLAKEQG :::::::::::::::::::::::::::::: XP_006 VSSSAARSRKLCPGRVNRGLSAQSTAATATMGGKNKQRTKGNLRPSNSGRAAELLAKEQG 20 30 40 50 60 70 40 50 60 70 80 90 pF1KA0 TVPGFIGFGTSQSDLGYVPAIQGAEEIDSLVDSDFRMVLRKLSKKDVTTKLKAMQEFGTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVPGFIGFGTSQSDLGYVPAIQGAEEIDSLVDSDFRMVLRKLSKKDVTTKLKAMQEFGTM 80 90 100 110 120 130 100 110 120 130 140 150 pF1KA0 CTERDTETVKGVLPYWPRIFCKISLDHDRRVREATQQAFEKLILKVKKQLAPYLKSLMGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CTERDTETVKGVLPYWPRIFCKISLDHDRRVREATQQAFEKLILKVKKQLAPYLKSLMGY 140 150 160 170 180 190 160 170 180 190 200 210 pF1KA0 WLMAQCDTYTPAAFAAKDAFEAAFPPSKQPEAIAFCKDEITSVLQDHLIKETPDTLSDPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WLMAQCDTYTPAAFAAKDAFEAAFPPSKQPEAIAFCKDEITSVLQDHLIKETPDTLSDPQ 200 210 220 230 240 250 220 230 240 250 260 270 pF1KA0 TVPEEEREAKFYRVVTCSLLALKRLLCLLPDNELDSLEEKFKSLLSQNKFWKYGKHSVPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVPEEEREAKFYRVVTCSLLALKRLLCLLPDNELDSLEEKFKSLLSQNKFWKYGKHSVPQ 260 270 280 290 300 310 280 290 300 310 320 330 pF1KA0 IRSAYFELVSALCQRIPQLMKEEASKVSPSVLLSIDDSDPIVCPALWEAVLYTLTTIEDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IRSAYFELVSALCQRIPQLMKEEASKVSPSVLLSIDDSDPIVCPALWEAVLYTLTTIEDC 320 330 340 350 360 370 340 350 360 370 380 390 pF1KA0 WLHVNAKKSVFPKLSTVIREGGRGLATVIYPYLLPFISKLPQSITNPKLDFFKNFLTSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WLHVNAKKSVFPKLSTVIREGGRGLATVIYPYLLPFISKLPQSITNPKLDFFKNFLTSLV 380 390 400 410 420 430 400 410 420 430 440 450 pF1KA0 AGLSTERTKTSSSESSAVISAFFECLRFIMQQNLGEEEIEQMLVNDQLIPFIDAVLKDPG :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGLSTERTKTSSLESSAVISAFFECLRFIMQQNLGEEEIEQMLVNDQLIPFIDAVLKDPG 440 450 460 470 480 490 460 470 480 490 500 510 pF1KA0 LQHGQLFNHLAETLSSWEAKADTEKDEKTAHNLENVLIHFWERLSEICVAKISEPEADVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQHGQLFNHLAETLSSWEAKADTEKDEKTAHNLENVLIHFWERLSEICVAKISEPEADVE 500 510 520 530 540 550 520 530 540 550 560 570 pF1KA0 SVLGVSNLLQVLQKPKSSLKSSKKKNGKVRFADEILESNKENEKCVSSEGEKIEGWELTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVLGVSNLLQVLQKPKSSLKSSKKKNGKVRFADEILESNKENEKCVSSEGEKIEGWELTT 560 570 580 590 600 610 580 590 600 610 620 630 pF1KA0 EPSLTHNSSGLLSPLRKKPLEDLVCKLADISINYVNERKSEQHLRFLSTLLDSFSSSRVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EPSLTHNSSGLLSPLRKKPLEDLVCKLADISINYVNERKSEQHLRFLSTLLDSFSSSRVF 620 630 640 650 660 670 640 650 660 670 680 690 pF1KA0 KMLLGDEKQSIVQAKPLEIAKLVQKNPAVQFLYQKLIGWLNEDQRKDFGFLVDILYSALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KMLLGDEKQSIVQAKPLEIAKLVQKNPAVQFLYQKLIGWLNEDQRKDFGFLVDILYSALR 680 690 700 710 720 730 700 710 720 730 740 750 pF1KA0 CCDNDMERKKVLDDLTKVDLKWNSLLKIIEKACPSSDKHALVTPWLKGDILGEKLVNLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CCDNDMERKKVLDDLTKVDLKWNSLLKIIEKACPSSDKHALVTPWLKGDILGEKLVNLAD 740 750 760 770 780 790 760 770 780 790 800 810 pF1KA0 CLCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVRLHETLFKTKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CLCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVRLHETLFKTKKL 800 810 820 830 840 850 820 830 840 850 860 pF1KA0 SEAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKEKTHLPD---FL :::::::::::::::::::::::::::::::::::::::::::::::::::::: .: XP_006 SEAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKEKTHLPGNSLLL 860 870 880 890 900 910 870 880 890 900 910 920 pF1KA0 ICKLKNTWLSGVNLLVHQTDSSYKESTFLHLSALWLKNQVQASSLDINSLQVLLSAVDDL : . : : XP_006 KCFVGNLRL 920 1766 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:04:44 2016 done: Thu Nov 3 10:04:46 2016 Total Scan time: 16.240 Total Display time: 0.430 Function used was FASTA [36.3.4 Apr, 2011]