FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0732, 1419 aa 1>>>pF1KA0732 1419 - 1419 aa - 1419 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8367+/-0.00106; mu= 13.0307+/- 0.064 mean_var=174.5958+/-34.850, 0's: 0 Z-trim(109.5): 37 B-trim: 144 in 1/51 Lambda= 0.097064 statistics sampled from 10884 (10908) to 10884 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.335), width: 16 Scan time: 6.270 The best scores are: opt bits E(32554) CCDS11016.1 SMG6 gene_id:23293|Hs108|chr17 (1419) 9444 1336.0 0 CCDS58498.1 SMG6 gene_id:23293|Hs108|chr17 ( 511) 3363 484.1 4.3e-136 >>CCDS11016.1 SMG6 gene_id:23293|Hs108|chr17 (1419 aa) initn: 9444 init1: 9444 opt: 9444 Z-score: 7152.9 bits: 1336.0 E(32554): 0 Smith-Waterman score: 9444; 99.9% identity (99.9% similar) in 1419 aa overlap (1-1419:1-1419) 10 20 30 40 50 60 pF1KA0 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPPLKKQVSVSS :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: CCDS11 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKTSAKEYRGTLRVTFDAEAMN ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: CCDS11 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKNSAKEYRGTLRVTFDAEAMN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 GKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 EECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 ELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 DPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 QEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGED 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 DIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLA 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFES 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 RDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPI 1330 1340 1350 1360 1370 1380 1390 1400 1410 pF1KA0 RLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG ::::::::::::::::::::::::::::::::::::::: CCDS11 RLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG 1390 1400 1410 >>CCDS58498.1 SMG6 gene_id:23293|Hs108|chr17 (511 aa) initn: 3363 init1: 3363 opt: 3363 Z-score: 2556.8 bits: 484.1 E(32554): 4.3e-136 Smith-Waterman score: 3363; 100.0% identity (100.0% similar) in 511 aa overlap (909-1419:1-511) 880 890 900 910 920 930 pF1KA0 GLGSLSPSDLNKRFILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTR :::::::::::::::::::::::::::::: CCDS58 METFPAVAEKVLKEFQVLLQHSPSPIGSTR 10 20 30 940 950 960 970 980 990 pF1KA0 MLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQL 40 50 60 70 80 90 1000 1010 1020 1030 1040 1050 pF1KA0 SSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVW 100 110 120 130 140 150 1060 1070 1080 1090 1100 1110 pF1KA0 STLADFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 STLADFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSD 160 170 180 190 200 210 1120 1130 1140 1150 1160 1170 pF1KA0 KVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDE 220 230 240 250 260 270 1180 1190 1200 1210 1220 1230 pF1KA0 EEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQ 280 290 300 310 320 330 1240 1250 1260 1270 1280 1290 pF1KA0 MELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGG 340 350 360 370 380 390 1300 1310 1320 1330 1340 1350 pF1KA0 YARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILS 400 410 420 430 440 450 1360 1370 1380 1390 1400 1410 pF1KA0 CCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQV 460 470 480 490 500 510 pF1KA0 G : CCDS58 G 1419 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:36:53 2016 done: Wed Nov 2 19:36:54 2016 Total Scan time: 6.270 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]