FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0732, 1419 aa
1>>>pF1KA0732 1419 - 1419 aa - 1419 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8367+/-0.00106; mu= 13.0307+/- 0.064
mean_var=174.5958+/-34.850, 0's: 0 Z-trim(109.5): 37 B-trim: 144 in 1/51
Lambda= 0.097064
statistics sampled from 10884 (10908) to 10884 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.335), width: 16
Scan time: 6.270
The best scores are: opt bits E(32554)
CCDS11016.1 SMG6 gene_id:23293|Hs108|chr17 (1419) 9444 1336.0 0
CCDS58498.1 SMG6 gene_id:23293|Hs108|chr17 ( 511) 3363 484.1 4.3e-136
>>CCDS11016.1 SMG6 gene_id:23293|Hs108|chr17 (1419 aa)
initn: 9444 init1: 9444 opt: 9444 Z-score: 7152.9 bits: 1336.0 E(32554): 0
Smith-Waterman score: 9444; 99.9% identity (99.9% similar) in 1419 aa overlap (1-1419:1-1419)
10 20 30 40 50 60
pF1KA0 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPPLKKQVSVSS
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
CCDS11 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKTSAKEYRGTLRVTFDAEAMN
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
CCDS11 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKNSAKEYRGTLRVTFDAEAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 EECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 ELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 QEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 DIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 SLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFES
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 RDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPI
1330 1340 1350 1360 1370 1380
1390 1400 1410
pF1KA0 RLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG
:::::::::::::::::::::::::::::::::::::::
CCDS11 RLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG
1390 1400 1410
>>CCDS58498.1 SMG6 gene_id:23293|Hs108|chr17 (511 aa)
initn: 3363 init1: 3363 opt: 3363 Z-score: 2556.8 bits: 484.1 E(32554): 4.3e-136
Smith-Waterman score: 3363; 100.0% identity (100.0% similar) in 511 aa overlap (909-1419:1-511)
880 890 900 910 920 930
pF1KA0 GLGSLSPSDLNKRFILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTR
::::::::::::::::::::::::::::::
CCDS58 METFPAVAEKVLKEFQVLLQHSPSPIGSTR
10 20 30
940 950 960 970 980 990
pF1KA0 MLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQL
40 50 60 70 80 90
1000 1010 1020 1030 1040 1050
pF1KA0 SSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVW
100 110 120 130 140 150
1060 1070 1080 1090 1100 1110
pF1KA0 STLADFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 STLADFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSD
160 170 180 190 200 210
1120 1130 1140 1150 1160 1170
pF1KA0 KVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDE
220 230 240 250 260 270
1180 1190 1200 1210 1220 1230
pF1KA0 EEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQ
280 290 300 310 320 330
1240 1250 1260 1270 1280 1290
pF1KA0 MELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGG
340 350 360 370 380 390
1300 1310 1320 1330 1340 1350
pF1KA0 YARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 YARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILS
400 410 420 430 440 450
1360 1370 1380 1390 1400 1410
pF1KA0 CCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 CCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQV
460 470 480 490 500 510
pF1KA0 G
:
CCDS58 G
1419 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:36:53 2016 done: Wed Nov 2 19:36:54 2016
Total Scan time: 6.270 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]