Result of FASTA (omim) for
pF1KA0732
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0732, 1419 aa
1>>>pF1KA0732 1419 - 1419 aa - 1419 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1143+/-0.000444; mu= 11.6907+/- 0.028
mean_var=207.1609+/-42.224, 0's: 0 Z-trim(117.2): 82 B-trim: 444 in 1/52
Lambda= 0.089109
statistics sampled from 28833 (28917) to 28833 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.339), width: 16
Scan time: 19.430
The best scores are: opt bits E(85289)
NP_060045 (OMIM: 610963) telomerase-binding protei (1419) 9444 1228.4 0
XP_011522071 (OMIM: 610963) PREDICTED: telomerase- (1388) 9257 1204.3 0
XP_005256626 (OMIM: 610963) PREDICTED: telomerase- (1388) 9257 1204.3 0
XP_011522074 (OMIM: 610963) PREDICTED: telomerase- ( 961) 6386 835.1 0
XP_016879887 (OMIM: 610963) PREDICTED: telomerase- ( 944) 6083 796.1 0
XP_005256627 (OMIM: 610963) PREDICTED: telomerase- ( 899) 5949 778.9 0
XP_011522076 (OMIM: 610963) PREDICTED: telomerase- ( 897) 5943 778.1 0
XP_011522075 (OMIM: 610963) PREDICTED: telomerase- ( 904) 5943 778.1 0
XP_011522077 (OMIM: 610963) PREDICTED: telomerase- ( 511) 3363 446.2 3e-124
XP_016879888 (OMIM: 610963) PREDICTED: telomerase- ( 511) 3363 446.2 3e-124
XP_005256628 (OMIM: 610963) PREDICTED: telomerase- ( 511) 3363 446.2 3e-124
NP_001243756 (OMIM: 610963) telomerase-binding pro ( 511) 3363 446.2 3e-124
NP_001243757 (OMIM: 610963) telomerase-binding pro ( 511) 3363 446.2 3e-124
NP_001269255 (OMIM: 610963) telomerase-binding pro ( 330) 1955 265.0 6.7e-70
NP_963862 (OMIM: 610964) protein SMG7 isoform 2 [H (1091) 333 57.0 9.4e-07
NP_775179 (OMIM: 610964) protein SMG7 isoform 1 [H (1137) 333 57.0 9.7e-07
XP_006711741 (OMIM: 610964) PREDICTED: protein SMG (1141) 333 57.0 9.7e-07
NP_963863 (OMIM: 610964) protein SMG7 isoform 4 [H (1178) 333 57.0 9.9e-07
XP_005245709 (OMIM: 610964) PREDICTED: protein SMG (1187) 333 57.0 1e-06
XP_016858456 (OMIM: 610964) PREDICTED: protein SMG (1120) 327 56.2 1.6e-06
XP_011508511 (OMIM: 610964) PREDICTED: protein SMG (1120) 327 56.2 1.6e-06
XP_011508510 (OMIM: 610964) PREDICTED: protein SMG (1166) 327 56.2 1.7e-06
XP_011508508 (OMIM: 610964) PREDICTED: protein SMG (1170) 327 56.2 1.7e-06
XP_016858455 (OMIM: 610964) PREDICTED: protein SMG (1170) 327 56.2 1.7e-06
NP_001317936 (OMIM: 610964) protein SMG7 isoform 6 (1170) 327 56.2 1.7e-06
XP_011508507 (OMIM: 610964) PREDICTED: protein SMG (1216) 327 56.2 1.7e-06
XP_005245705 (OMIM: 610964) PREDICTED: protein SMG (1216) 327 56.2 1.7e-06
XP_005245706 (OMIM: 610964) PREDICTED: protein SMG (1216) 327 56.2 1.7e-06
XP_005245710 (OMIM: 610964) PREDICTED: protein SMG (1169) 326 56.1 1.8e-06
XP_011508509 (OMIM: 610964) PREDICTED: protein SMG (1169) 326 56.1 1.8e-06
XP_016858457 (OMIM: 610964) PREDICTED: protein SMG (1049) 302 53.0 1.4e-05
XP_011508512 (OMIM: 610964) PREDICTED: protein SMG (1099) 302 53.0 1.5e-05
NP_001167532 (OMIM: 610964) protein SMG7 isoform 5 (1145) 302 53.0 1.5e-05
NP_001310543 (OMIM: 610962) protein SMG5 isoform 2 ( 963) 242 45.2 0.0029
NP_001310544 (OMIM: 610962) protein SMG5 isoform 3 ( 970) 242 45.2 0.0029
NP_056142 (OMIM: 610962) protein SMG5 isoform 1 [H (1016) 242 45.2 0.003
>>NP_060045 (OMIM: 610963) telomerase-binding protein ES (1419 aa)
initn: 9444 init1: 9444 opt: 9444 Z-score: 6570.9 bits: 1228.4 E(85289): 0
Smith-Waterman score: 9444; 99.9% identity (99.9% similar) in 1419 aa overlap (1-1419:1-1419)
10 20 30 40 50 60
pF1KA0 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPPLKKQVSVSS
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
NP_060 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKTSAKEYRGTLRVTFDAEAMN
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
NP_060 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKNSAKEYRGTLRVTFDAEAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 EECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 ELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 QEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 DIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 SLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFES
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 RDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPI
1330 1340 1350 1360 1370 1380
1390 1400 1410
pF1KA0 RLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG
:::::::::::::::::::::::::::::::::::::::
NP_060 RLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG
1390 1400 1410
>>XP_011522071 (OMIM: 610963) PREDICTED: telomerase-bind (1388 aa)
initn: 9257 init1: 9257 opt: 9257 Z-score: 6441.1 bits: 1204.3 E(85289): 0
Smith-Waterman score: 9257; 99.9% identity (99.9% similar) in 1388 aa overlap (32-1419:1-1388)
10 20 30 40 50 60
pF1KA0 AEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLRN
::::::::::::::::::::::::::::::
XP_011 MKELKEARPRKDNRRPDLEIYKPGLSRLRN
10 20 30
70 80 90 100 110 120
pF1KA0 KPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQESF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQESF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KA0 PRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEEDE
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA0 CRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGSA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 KRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPPLKKQVSVSST
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 KRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSST
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 DSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKTSAKEYRGTLRVTFDAEAMNK
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_011 DSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKNSAKEYRGTLRVTFDAEAMNK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 ESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVNS
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 AGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTDD
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 EVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYPG
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 PYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLSR
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 DRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVKD
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 PNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKYA
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 LISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTRR
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 KLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKKS
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 TFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAHG
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 KLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSE
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA0 ECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLKE
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KA0 LLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYKD
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KA0 PDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCGQ
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KA0 EEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDD
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KA0 IRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLAS
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KA0 LARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESR
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KA0 DSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIR
1300 1310 1320 1330 1340 1350
1390 1400 1410
pF1KA0 LLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG
::::::::::::::::::::::::::::::::::::::
XP_011 LLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG
1360 1370 1380
>>XP_005256626 (OMIM: 610963) PREDICTED: telomerase-bind (1388 aa)
initn: 9257 init1: 9257 opt: 9257 Z-score: 6441.1 bits: 1204.3 E(85289): 0
Smith-Waterman score: 9257; 99.9% identity (99.9% similar) in 1388 aa overlap (32-1419:1-1388)
10 20 30 40 50 60
pF1KA0 AEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLRN
::::::::::::::::::::::::::::::
XP_005 MKELKEARPRKDNRRPDLEIYKPGLSRLRN
10 20 30
70 80 90 100 110 120
pF1KA0 KPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQESF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQESF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KA0 PRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEEDE
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA0 CRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGSA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 KRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPPLKKQVSVSST
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_005 KRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSST
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 DSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKTSAKEYRGTLRVTFDAEAMNK
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_005 DSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKNSAKEYRGTLRVTFDAEAMNK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 ESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVNS
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 AGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTDD
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 EVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYPG
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 PYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLSR
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 DRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVKD
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 PNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKYA
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 LISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTRR
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 KLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKKS
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 TFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAHG
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 KLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSE
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA0 ECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLKE
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KA0 LLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYKD
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KA0 PDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCGQ
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KA0 EEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDD
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KA0 IRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLAS
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KA0 LARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESR
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KA0 DSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIR
1300 1310 1320 1330 1340 1350
1390 1400 1410
pF1KA0 LLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG
::::::::::::::::::::::::::::::::::::::
XP_005 LLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG
1360 1370 1380
>>XP_011522074 (OMIM: 610963) PREDICTED: telomerase-bind (961 aa)
initn: 6386 init1: 6386 opt: 6386 Z-score: 4448.4 bits: 835.1 E(85289): 0
Smith-Waterman score: 6386; 99.8% identity (99.9% similar) in 956 aa overlap (1-956:1-956)
10 20 30 40 50 60
pF1KA0 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPPLKKQVSVSS
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_011 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKTSAKEYRGTLRVTFDAEAMN
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKNSAKEYRGTLRVTFDAEAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKGVLQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 EECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLK
XP_011 S
>>XP_016879887 (OMIM: 610963) PREDICTED: telomerase-bind (944 aa)
initn: 6081 init1: 6081 opt: 6083 Z-score: 4238.0 bits: 796.1 E(85289): 0
Smith-Waterman score: 6083; 97.1% identity (97.8% similar) in 940 aa overlap (1-940:1-932)
10 20 30 40 50 60
pF1KA0 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPPLKKQVSVSS
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_016 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKTSAKEYRGTLRVTFDAEAMN
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_016 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKNSAKEYRGTLRVTFDAEAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFS
:::::::: :: .. .. ::: :.:
XP_016 GKLFTRIG--------EKGIEVCKTRKAMSPSHTQHRRLLPNYEEDVKCGRC
910 920 930 940
970 980 990 1000 1010 1020
pF1KA0 EECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLK
>>XP_005256627 (OMIM: 610963) PREDICTED: telomerase-bind (899 aa)
initn: 5943 init1: 5943 opt: 5949 Z-score: 4145.2 bits: 778.9 E(85289): 0
Smith-Waterman score: 5949; 99.0% identity (99.3% similar) in 898 aa overlap (1-897:1-898)
10 20 30 40 50 60
pF1KA0 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPPLKKQVSVSS
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_005 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKTSAKEYRGTLRVTFDAEAMN
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_005 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKNSAKEYRGTLRVTFDAEAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
790 800 810 820 830 840
850 860 870 880 890
pF1KA0 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSD-LNKRFILSFLHA
::::::::::::::::::::::::::::::::::::::::::::::: . : :.::
XP_005 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDATSPRRNLQFLA
850 860 870 880 890
900 910 920 930 940 950
pF1KA0 HGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCF
>>XP_011522076 (OMIM: 610963) PREDICTED: telomerase-bind (897 aa)
initn: 5943 init1: 5943 opt: 5943 Z-score: 4141.0 bits: 778.1 E(85289): 0
Smith-Waterman score: 5943; 99.8% identity (99.9% similar) in 887 aa overlap (1-887:1-887)
10 20 30 40 50 60
pF1KA0 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPPLKKQVSVSS
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_011 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKTSAKEYRGTLRVTFDAEAMN
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKNSAKEYRGTLRVTFDAEAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDRQRTKREFGR
850 860 870 880 890
910 920 930 940 950 960
pF1KA0 GKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFS
>>XP_011522075 (OMIM: 610963) PREDICTED: telomerase-bind (904 aa)
initn: 5943 init1: 5943 opt: 5943 Z-score: 4141.0 bits: 778.1 E(85289): 0
Smith-Waterman score: 5943; 99.8% identity (99.9% similar) in 887 aa overlap (1-887:1-887)
10 20 30 40 50 60
pF1KA0 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPPLKKQVSVSS
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_011 AKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKTSAKEYRGTLRVTFDAEAMN
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 TDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKNSAKEYRGTLRVTFDAEAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAH
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDDLFRSGEFNAVAP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFS
XP_011 EFLE
>>XP_011522077 (OMIM: 610963) PREDICTED: telomerase-bind (511 aa)
initn: 3363 init1: 3363 opt: 3363 Z-score: 2351.7 bits: 446.2 E(85289): 3e-124
Smith-Waterman score: 3363; 100.0% identity (100.0% similar) in 511 aa overlap (909-1419:1-511)
880 890 900 910 920 930
pF1KA0 GLGSLSPSDLNKRFILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTR
::::::::::::::::::::::::::::::
XP_011 METFPAVAEKVLKEFQVLLQHSPSPIGSTR
10 20 30
940 950 960 970 980 990
pF1KA0 MLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQL
40 50 60 70 80 90
1000 1010 1020 1030 1040 1050
pF1KA0 SSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVW
100 110 120 130 140 150
1060 1070 1080 1090 1100 1110
pF1KA0 STLADFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STLADFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSD
160 170 180 190 200 210
1120 1130 1140 1150 1160 1170
pF1KA0 KVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDE
220 230 240 250 260 270
1180 1190 1200 1210 1220 1230
pF1KA0 EEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQ
280 290 300 310 320 330
1240 1250 1260 1270 1280 1290
pF1KA0 MELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGG
340 350 360 370 380 390
1300 1310 1320 1330 1340 1350
pF1KA0 YARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILS
400 410 420 430 440 450
1360 1370 1380 1390 1400 1410
pF1KA0 CCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQV
460 470 480 490 500 510
pF1KA0 G
:
XP_011 G
>>XP_016879888 (OMIM: 610963) PREDICTED: telomerase-bind (511 aa)
initn: 3363 init1: 3363 opt: 3363 Z-score: 2351.7 bits: 446.2 E(85289): 3e-124
Smith-Waterman score: 3363; 100.0% identity (100.0% similar) in 511 aa overlap (909-1419:1-511)
880 890 900 910 920 930
pF1KA0 GLGSLSPSDLNKRFILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTR
::::::::::::::::::::::::::::::
XP_016 METFPAVAEKVLKEFQVLLQHSPSPIGSTR
10 20 30
940 950 960 970 980 990
pF1KA0 MLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQL
40 50 60 70 80 90
1000 1010 1020 1030 1040 1050
pF1KA0 SSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVW
100 110 120 130 140 150
1060 1070 1080 1090 1100 1110
pF1KA0 STLADFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STLADFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSD
160 170 180 190 200 210
1120 1130 1140 1150 1160 1170
pF1KA0 KVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDE
220 230 240 250 260 270
1180 1190 1200 1210 1220 1230
pF1KA0 EEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQ
280 290 300 310 320 330
1240 1250 1260 1270 1280 1290
pF1KA0 MELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGG
340 350 360 370 380 390
1300 1310 1320 1330 1340 1350
pF1KA0 YARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILS
400 410 420 430 440 450
1360 1370 1380 1390 1400 1410
pF1KA0 CCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQV
460 470 480 490 500 510
pF1KA0 G
:
XP_016 G
1419 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:36:54 2016 done: Wed Nov 2 19:36:57 2016
Total Scan time: 19.430 Total Display time: 0.460
Function used was FASTA [36.3.4 Apr, 2011]