FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0737, 621 aa 1>>>pF1KA0737 621 - 621 aa - 621 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.2795+/-0.000433; mu= -16.9395+/- 0.027 mean_var=503.4033+/-105.133, 0's: 0 Z-trim(123.4): 50 B-trim: 2018 in 1/61 Lambda= 0.057163 statistics sampled from 43125 (43188) to 43125 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.506), width: 16 Scan time: 10.160 The best scores are: opt bits E(85289) NP_055643 (OMIM: 614032) TOX high mobility group b ( 621) 4134 355.7 2.9e-97 NP_001290452 (OMIM: 614032) TOX high mobility grou ( 598) 3963 341.5 4.9e-93 NP_001139660 (OMIM: 611416) TOX high mobility grou ( 571) 1181 112.1 5.5e-24 XP_005255949 (OMIM: 611416) PREDICTED: TOX high mo ( 575) 1181 112.1 5.5e-24 XP_011521304 (OMIM: 611416) PREDICTED: TOX high mo ( 553) 1169 111.1 1.1e-23 XP_016878631 (OMIM: 611416) PREDICTED: TOX high mo ( 572) 1169 111.1 1.1e-23 NP_001073899 (OMIM: 611416) TOX high mobility grou ( 576) 1169 111.1 1.1e-23 NP_055544 (OMIM: 606863) thymocyte selection-assoc ( 526) 926 91.0 1.1e-17 XP_016869574 (OMIM: 606863) PREDICTED: thymocyte s ( 504) 880 87.2 1.5e-16 XP_006723947 (OMIM: 611163) PREDICTED: TOX high mo ( 515) 750 76.5 2.5e-13 NP_001092267 (OMIM: 611163) TOX high mobility grou ( 506) 749 76.4 2.6e-13 NP_116272 (OMIM: 611163) TOX high mobility group b ( 464) 734 75.2 5.8e-13 NP_001092266 (OMIM: 611163) TOX high mobility grou ( 464) 734 75.2 5.8e-13 NP_001092268 (OMIM: 611163) TOX high mobility grou ( 488) 618 65.6 4.6e-10 XP_016883598 (OMIM: 611163) PREDICTED: TOX high mo ( 305) 599 63.9 9.5e-10 >>NP_055643 (OMIM: 614032) TOX high mobility group box f (621 aa) initn: 4134 init1: 4134 opt: 4134 Z-score: 1867.3 bits: 355.7 E(85289): 2.9e-97 Smith-Waterman score: 4134; 100.0% identity (100.0% similar) in 621 aa overlap (1-621:1-621) 10 20 30 40 50 60 pF1KA0 MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 DLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 IKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPSIVVNSTLSSYVANQASSGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPSIVVNSTLSSYVANQASSGAG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 GQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 RSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 RINLQQQPPPLQIKSVPLPTLKMQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RINLQQQPPPLQIKSVPLPTLKMQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 ITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKH 550 560 570 580 590 600 610 620 pF1KA0 CRDVFLAWVASRNSNTVVFVK ::::::::::::::::::::: NP_055 CRDVFLAWVASRNSNTVVFVK 610 620 >>NP_001290452 (OMIM: 614032) TOX high mobility group bo (598 aa) initn: 3963 init1: 3963 opt: 3963 Z-score: 1791.3 bits: 341.5 E(85289): 4.9e-93 Smith-Waterman score: 3963; 100.0% identity (100.0% similar) in 597 aa overlap (25-621:2-598) 10 20 30 40 50 60 pF1KA0 MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFD :::::::::::::::::::::::::::::::::::: NP_001 METFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFD 10 20 30 70 80 90 100 110 120 pF1KA0 DLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANP 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA0 PVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPT 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA0 SSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAA 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA0 IKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATV 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA0 ETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPSIVVNSTLSSYVANQASSGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPSIVVNSTLSSYVANQASSGAG 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA0 GQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVT 340 350 360 370 380 390 430 440 450 460 470 480 pF1KA0 RSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKV 400 410 420 430 440 450 490 500 510 520 530 540 pF1KA0 RINLQQQPPPLQIKSVPLPTLKMQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RINLQQQPPPLQIKSVPLPTLKMQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEM 460 470 480 490 500 510 550 560 570 580 590 600 pF1KA0 ITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKH 520 530 540 550 560 570 610 620 pF1KA0 CRDVFLAWVASRNSNTVVFVK ::::::::::::::::::::: NP_001 CRDVFLAWVASRNSNTVVFVK 580 590 >>NP_001139660 (OMIM: 611416) TOX high mobility group bo (571 aa) initn: 915 init1: 566 opt: 1181 Z-score: 551.7 bits: 112.1 E(85289): 5.5e-24 Smith-Waterman score: 1208; 42.7% identity (67.0% similar) in 548 aa overlap (5-536:27-549) 10 20 30 pF1KA0 MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFE :.:.::.... .. :....:::::::::::::: NP_001 MKCQPRSGARRIEERLHYLITTYLKFGNNNNYMNMAEANNAFFAASETFHTPSLGDEEFE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 IPPISL--DSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMP-VGMTHGLMEQ ::::. .:::.:.. ::. :. :.:: :: . :. :. :.::.: . ....:.:: NP_001 IPPITPPPESDPALGMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLPSITISRNLVEQ 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 GGGLLSGGLTMDLDHSIGTQYSANPPVTID--VPMTDMT-SGLMGHSQLTTIDQSELSSQ : : :.:: :: .:. .:: .: . . : ::: . ::.: .:::::.::.::.: NP_001 DGVLHSSGLHMDQSHTQVSQYRQDPSLIMRSIVHMTDAARSGVMPPAQLTTINQSQLSAQ 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 LGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAP :::.:::... . :: :.::::.::..:. ... : . ..: .. ..::: :.: NP_001 LGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAI-GEKRAAPDSGKKPKTP 190 200 210 220 230 220 230 240 250 260 270 pF1KA0 KKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVY ::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVY 240 250 260 270 280 290 280 290 300 310 320 330 pF1KA0 KRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPASPAPASI ::::::::::::::::::. . .:..:..: .:: . .:. .. NP_001 KRKTEAAKKEYLKALAAYRASLVSKAAAESAE------AQT-----IRSVQQ------TL 300 310 320 330 340 340 350 360 370 380 pF1KA0 EPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQM---LP-----SSITMSQG :. :...:. ::.. . .:: . : .. . : : . :: .:.:.. . NP_001 ASTNLTSSLLLNTPLSQHGTVSASPQTL-QQSLPRSIAPKPLTMRLPMNQIVTSVTIA-A 350 360 370 380 390 400 390 400 410 420 430 440 pF1KA0 GMVTVIPATVVTSRGLQL-GQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPRL .: . : : ...: : . :.. .. ..:: :.: . :: .:. .: NP_001 NMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQ-HQMQLQQQQQQQQQQMQQMQQQQL 410 420 430 440 450 450 460 470 480 490 500 pF1KA0 QPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPLPTLK- : ..:. : ::: .. :: .:: :. :: :: :: . . : :. NP_001 QQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQ--INQQQLQQQLQ-QRLQLQQLQH 460 470 480 490 500 510 510 520 530 540 550 560 pF1KA0 MQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSGS :: : . :: . .:: .. .:.: . NP_001 MQHQSQPSPRQHSPVASQITSP-IPAIGSPQPASQQHQSQIQSQTQTQVLSQVSIF 520 530 540 550 560 570 570 580 590 600 610 620 pF1KA0 PVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVVFVK >>XP_005255949 (OMIM: 611416) PREDICTED: TOX high mobili (575 aa) initn: 915 init1: 566 opt: 1181 Z-score: 551.6 bits: 112.1 E(85289): 5.5e-24 Smith-Waterman score: 1208; 42.7% identity (67.0% similar) in 548 aa overlap (5-536:31-553) 10 20 30 pF1KA0 MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGD :.:.::.... .. :....:::::::::: XP_005 MDVRFYPAAAGDPASLDFAQCLGYYGYSKFGNNNNYMNMAEANNAFFAASETFHTPSLGD 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 EEFEIPPISL--DSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMP-VGMTHG ::::::::. .:::.:.. ::. :. :.:: :: . :. :. :.::.: . .... XP_005 EEFEIPPITPPPESDPALGMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLPSITISRN 70 80 90 100 110 120 100 110 120 130 140 pF1KA0 LMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTID--VPMTDMT-SGLMGHSQLTTIDQSE :.:: : : :.:: :: .:. .:: .: . . : ::: . ::.: .:::::.::. XP_005 LVEQDGVLHSSGLHMDQSHTQVSQYRQDPSLIMRSIVHMTDAARSGVMPPAQLTTINQSQ 130 140 150 160 170 180 150 160 170 180 190 200 pF1KA0 LSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGKK ::.::::.:::... . :: :.::::.::..:. ... : . ..: .. ..::: XP_005 LSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAI-GEKRAAPDSGKK 190 200 210 220 230 210 220 230 240 250 260 pF1KA0 QKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQ :.:::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQ 240 250 260 270 280 290 270 280 290 300 310 320 pF1KA0 KQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPASPA ::::::::::::::::::::::. . .:..:..: .:: . .:. XP_005 KQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAE------AQT-----IRSVQQ---- 300 310 320 330 340 330 340 350 360 370 380 pF1KA0 PASIEPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQM---LP-----SSIT .. :. :...:. ::.. . .:: . : .. . : : . :: .:.: XP_005 --TLASTNLTSSLLLNTPLSQHGTVSASPQTL-QQSLPRSIAPKPLTMRLPMNQIVTSVT 350 360 370 380 390 400 390 400 410 420 430 pF1KA0 MSQGGMVTVIPATVVTSRGLQL-GQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLP .. ..: . : : ...: : . :.. .. ..:: :.: . :: .:. XP_005 IA-ANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQ-HQMQLQQQQQQQQQQMQQMQ 410 420 430 440 450 440 450 460 470 480 490 pF1KA0 PPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPLP .:: ..:. : ::: .. :: .:: :. :: :: :: . . : XP_005 QQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQ--INQQQLQQQLQ-QRLQLQ 460 470 480 490 500 510 500 510 520 530 540 550 pF1KA0 TLK-MQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVEL :. :: : . :: . .:: .. .:.: . XP_005 QLQHMQHQSQPSPRQHSPVASQITSP-IPAIGSPQPASQQHQSQIQSQTQTQVLSQVSIF 520 530 540 550 560 570 560 570 580 590 600 610 pF1KA0 VSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVV >>XP_011521304 (OMIM: 611416) PREDICTED: TOX high mobili (553 aa) initn: 872 init1: 566 opt: 1169 Z-score: 546.5 bits: 111.1 E(85289): 1.1e-23 Smith-Waterman score: 1196; 42.6% identity (66.8% similar) in 549 aa overlap (5-536:8-531) 10 20 30 40 50 pF1KA0 MEFPGGNDNYLTITGPSHPFLSGAE-TFHTPSLGDEEFEIPPISL--DSDPSLAVSD :.:.::.... .. :....: :::::::::::::::::. .:::.:.. : XP_011 MAQFICFGNNNNYMNMAEANNAFFAASEQTFHTPSLGDEEFEIPPITPPPESDPALGMPD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 VVGHFDDLADPSSSQDGSFSAQYGVQTLDMP-VGMTHGLMEQGGGLLSGGLTMDLDHSIG :. :. :.:: :: . :. :. :.::.: . ....:.:: : : :.:: :: .:. XP_011 VLLPFQALSDPLPSQGSEFTPQFPPQSLDLPSITISRNLVEQDGVLHSSGLHMDQSHTQV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 TQYSANPPVTID--VPMTDMT-SGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPE .:: .: . . : ::: . ::.: .:::::.::.::.::::.:::... . :: XP_011 SQYRQDPSLIMRSIVHMTDAARSGVMPPAQLTTINQSQLSAQLGLNLGGASMPHTSPSPP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 DRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAY :.::::.::..:. ... : . ..: .. ..::: :.:::.::::::::::::::: XP_011 ASKSATPSPSSSINEEDADEANRAI-GEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAY 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 ALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA0 KDNQECQATVETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPSIVVNSTLSSY . . .:..:..: .:: . .:. .. :. :...:. ::.. XP_011 RASLVSKAAAESAE------AQT-----IRSVQQ------TLASTNLTSSLLLNTPLSQH 300 310 320 330 340 360 370 380 390 400 pF1KA0 VANQASSGAGGQPNITKLIITKQM---LP-----SSITMSQGGMVTVIPATVVTSRGLQL . .:: . : .. . : : . :: .:.:.. ..: . : : ...: : . XP_011 GTVSASPQTL-QQSLPRSIAPKPLTMRLPMNQIVTSVTIA-ANMPSNIGAPLISSMGTTM 350 360 370 380 390 400 410 420 430 440 450 460 pF1KA0 -GQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVT :.. .. ..:: :.: . :: .:. .:: ..:. : ::: XP_011 VGSAPSTQVSPSVQTQQ-HQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHF 410 420 430 440 450 470 480 490 500 510 520 pF1KA0 ILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPLPTLK-MQTTLVPPTVESSPERPM .. :: .:: :. :: :: :: . . : :. :: : . :: . XP_011 QHHMQQHLQQQQQHLQQQ--INQQQLQQQLQ-QRLQLQQLQHMQHQSQPSPRQHSPVASQ 460 470 480 490 500 510 530 540 550 560 570 580 pF1KA0 NNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENP .:: .. .:.: . XP_011 ITSP-IPAIGSPQPASQQHQSQIQSQTQTQVLSQVSIF 520 530 540 550 >>XP_016878631 (OMIM: 611416) PREDICTED: TOX high mobili (572 aa) initn: 872 init1: 566 opt: 1169 Z-score: 546.3 bits: 111.1 E(85289): 1.1e-23 Smith-Waterman score: 1196; 42.6% identity (66.8% similar) in 549 aa overlap (5-536:27-550) 10 20 30 pF1KA0 MEFPGGNDNYLTITGPSHPFLSGAE-TFHTPSLGDEEF :.:.::.... .. :....: :::::::::::: XP_016 MKCQPRSGARRIEERLHYLITTYLKFGNNNNYMNMAEANNAFFAASEQTFHTPSLGDEEF 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 EIPPISL--DSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMP-VGMTHGLME :::::. .:::.:.. ::. :. :.:: :: . :. :. :.::.: . ....:.: XP_016 EIPPITPPPESDPALGMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLPSITISRNLVE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 QGGGLLSGGLTMDLDHSIGTQYSANPPVTID--VPMTDMT-SGLMGHSQLTTIDQSELSS : : : :.:: :: .:. .:: .: . . : ::: . ::.: .:::::.::.::. XP_016 QDGVLHSSGLHMDQSHTQVSQYRQDPSLIMRSIVHMTDAARSGVMPPAQLTTINQSQLSA 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 QLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGKKQKA ::::.:::... . :: :.::::.::..:. ... : . ..: .. ..::: :. XP_016 QLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAI-GEKRAAPDSGKKPKT 190 200 210 220 230 220 230 240 250 260 270 pF1KA0 PKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQV :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQV 240 250 260 270 280 290 280 290 300 310 320 330 pF1KA0 YKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPASPAPAS :::::::::::::::::::. . .:..:..: .:: . .:. . XP_016 YKRKTEAAKKEYLKALAAYRASLVSKAAAESAE------AQT-----IRSVQQ------T 300 310 320 330 340 340 350 360 370 380 pF1KA0 IEPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQM---LP-----SSITMSQ . :. :...:. ::.. . .:: . : .. . : : . :: .:.:.. XP_016 LASTNLTSSLLLNTPLSQHGTVSASPQTL-QQSLPRSIAPKPLTMRLPMNQIVTSVTIA- 350 360 370 380 390 400 390 400 410 420 430 440 pF1KA0 GGMVTVIPATVVTSRGLQL-GQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPR ..: . : : ...: : . :.. .. ..:: :.: . :: .:. . XP_016 ANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQ-HQMQLQQQQQQQQQQMQQMQQQQ 410 420 430 440 450 450 460 470 480 490 500 pF1KA0 LQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPLPTLK :: ..:. : ::: .. :: .:: :. :: :: :: . . : :. XP_016 LQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQ--INQQQLQQQLQ-QRLQLQQLQ 460 470 480 490 500 510 510 520 530 540 550 560 pF1KA0 -MQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSG :: : . :: . .:: .. .:.: . XP_016 HMQHQSQPSPRQHSPVASQITSP-IPAIGSPQPASQQHQSQIQSQTQTQVLSQVSIF 520 530 540 550 560 570 570 580 590 600 610 620 pF1KA0 SPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVVFVK >>NP_001073899 (OMIM: 611416) TOX high mobility group bo (576 aa) initn: 872 init1: 566 opt: 1169 Z-score: 546.3 bits: 111.1 E(85289): 1.1e-23 Smith-Waterman score: 1196; 42.6% identity (66.8% similar) in 549 aa overlap (5-536:31-554) 10 20 30 pF1KA0 MEFPGGNDNYLTITGPSHPFLSGAE-TFHTPSLG :.:.::.... .. :....: :::::::: NP_001 MDVRFYPAAAGDPASLDFAQCLGYYGYSKFGNNNNYMNMAEANNAFFAASEQTFHTPSLG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 DEEFEIPPISL--DSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMP-VGMTH :::::::::. .:::.:.. ::. :. :.:: :: . :. :. :.::.: . ... NP_001 DEEFEIPPITPPPESDPALGMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLPSITISR 70 80 90 100 110 120 100 110 120 130 140 pF1KA0 GLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTID--VPMTDMT-SGLMGHSQLTTIDQS .:.:: : : :.:: :: .:. .:: .: . . : ::: . ::.: .:::::.:: NP_001 NLVEQDGVLHSSGLHMDQSHTQVSQYRQDPSLIMRSIVHMTDAARSGVMPPAQLTTINQS 130 140 150 160 170 180 150 160 170 180 190 200 pF1KA0 ELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGK .::.::::.:::... . :: :.::::.::..:. ... : . ..: .. ..:: NP_001 QLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAI-GEKRAAPDSGK 190 200 210 220 230 210 220 230 240 250 260 pF1KA0 KQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEE : :.:::.:::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEE 240 250 260 270 280 290 270 280 290 300 310 320 pF1KA0 QKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPASP :::::::::::::::::::::::. . .:..:..: .:: . .:. NP_001 QKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAE------AQT-----IRSVQQ--- 300 310 320 330 340 330 340 350 360 370 pF1KA0 APASIEPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQM---LP-----SSI .. :. :...:. ::.. . .:: . : .. . : : . :: .:. NP_001 ---TLASTNLTSSLLLNTPLSQHGTVSASPQTL-QQSLPRSIAPKPLTMRLPMNQIVTSV 350 360 370 380 390 400 380 390 400 410 420 430 pF1KA0 TMSQGGMVTVIPATVVTSRGLQL-GQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQL :.. ..: . : : ...: : . :.. .. ..:: :.: . :: .:. NP_001 TIA-ANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQ-HQMQLQQQQQQQQQQMQQM 410 420 430 440 450 440 450 460 470 480 490 pF1KA0 PPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPL .:: ..:. : ::: .. :: .:: :. :: :: :: . . : NP_001 QQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQ--INQQQLQQQLQ-QRLQL 460 470 480 490 500 510 500 510 520 530 540 550 pF1KA0 PTLK-MQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVE :. :: : . :: . .:: .. .:.: . NP_001 QQLQHMQHQSQPSPRQHSPVASQITSP-IPAIGSPQPASQQHQSQIQSQTQTQVLSQVSI 520 530 540 550 560 570 560 570 580 590 600 610 pF1KA0 LVSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTV NP_001 F >>NP_055544 (OMIM: 606863) thymocyte selection-associate (526 aa) initn: 1060 init1: 748 opt: 926 Z-score: 438.5 bits: 91.0 E(85289): 1.1e-17 Smith-Waterman score: 989; 36.5% identity (59.3% similar) in 600 aa overlap (6-594:37-514) 10 20 30 pF1KA0 MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDE :.. :...: ::. .. ..... ::: .: NP_055 PPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPGPSLESE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 EFEIPPISLDSDP--SLA-VSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGL .:.::::. : : ::. ...: . . .: : . ..: . . :..:.: . .. NP_055 DFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMN-HNGLL--PFHPQNMDLPEITVSNM 70 80 90 100 110 120 100 110 120 130 140 pF1KA0 MEQGGGLLSGGLTM--DLDHSIGTQYSANPPVTIDVPM---TDMTS--GLMGHSQLTTID . : : :::..... :. . :::::..: .. : .:. . :.: :.:::::. NP_055 LGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLTTIN 130 140 150 160 170 180 150 160 170 180 190 200 pF1KA0 QSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEA ::.::.::::..::... . :: :.::::.::.::: .: . ..: . . NP_055 QSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPASDM 190 200 210 220 230 240 210 220 230 240 250 260 pF1KA0 GKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLG ::: :.:::.:::::::::::::::::::::::::::::::::::::::::::::::.:: NP_055 GKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLG 250 260 270 280 290 300 270 280 290 300 310 320 pF1KA0 EEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPA ::::::::.::::::::::: ::::. . .. : :.. .: .:: . NP_055 EEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDV------KTSQPPQLI----- 310 320 330 340 350 330 340 350 360 370 380 pF1KA0 SPAPASIEPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQGG . :. .. :. . : . :::. .: : .:..: : :: NP_055 NSKPSVFHGPSQAHSALY---LSSHYHQQP----GMNPHLT------AMHPS-------- 360 370 380 390 390 400 410 420 430 440 pF1KA0 MVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPRLQP .: ... .:..: :: :. :.: . :: NP_055 ----LPRNIAP--------------KPNNQMP-VTVSI----------ANMAVSPP---- 400 410 450 460 470 480 490 500 pF1KA0 PPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKS-VPLPTLKMQ :::: .:: .:... .:: :: .:::: ... :.:..: . ::... NP_055 PPLQI--SPPLHQHLN-MQQHQPL-TMQQPLGNQL---------PMQVQSALHSPTMQQG 420 430 440 450 460 510 520 530 540 550 560 pF1KA0 TTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSGSPV :: .:. .:. :. : ...:... : NP_055 FTL---------------QPDYQTIINPTS-TAAQVVTQAMEYV---------------- 470 480 490 570 580 590 600 610 620 pF1KA0 ALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVVFVK ::::.::: ::.:.:::. NP_055 ---------RSGCRNPPPQPVDWNNDYCSSGGMQRDKALYLT 500 510 520 >>XP_016869574 (OMIM: 606863) PREDICTED: thymocyte selec (504 aa) initn: 959 init1: 748 opt: 880 Z-score: 418.2 bits: 87.2 E(85289): 1.5e-16 Smith-Waterman score: 949; 36.7% identity (58.4% similar) in 594 aa overlap (15-594:22-492) 10 20 30 40 pF1KA0 MEFPGGNDNYLTITGPS---HPFLSGAETFHTPSLGDEEFEIPPISLDSDP-- ::: :. . ... ::: .:.:.::::. : : XP_016 MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCN-KSYPGPSLESEDFNIPPITPPSLPDH 10 20 30 40 50 50 60 70 80 90 100 pF1KA0 SLA-VSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTM- ::. ...: . . .: : . ..: . . :..:.: . ... : : :::..... XP_016 SLVHLNEVESGYHSLCHPMN-HNGLLP--FHPQNMDLPEITVSNMLGQDGTLLSNSISVM 60 70 80 90 100 110 110 120 130 140 150 160 pF1KA0 -DLDHSIGTQYSANPPVTIDVPM---TDMTS--GLMGHSQLTTIDQSELSSQLGLSLGGG :. . :::::..: .. : .:. . :.: :.:::::.::.::.::::..::. XP_016 PDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLTTINQSQLSAQLGLNMGGS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KA0 TILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDP .. . :: :.::::.::.::: .: . ..: . . ::: :.:::.::::: XP_016 NVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPASDMGKKPKTPKKKKKKDP 180 190 200 210 220 230 230 240 250 260 270 280 pF1KA0 NEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAK ::::::::::::::::::::::::::::::::::::::::::.::::::::::.:::::: XP_016 NEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAK 240 250 260 270 280 290 290 300 310 320 330 340 pF1KA0 KEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPS ::::: ::::. . .. : :.. .: .:: . . :. .. :. . : XP_016 KEYLKQLAAYRASLVSKSYSEPVDV------KTSQPPQLI-----NSKPSVFHGPSQAHS 300 310 320 330 340 350 360 370 380 390 400 pF1KA0 IVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGL . :::. .: : .:..: : :: .: ... XP_016 ALY---LSSHYHQQ----PGMNPHLTA------MHPS------------LPRNIAP---- 350 360 370 410 420 430 440 450 460 pF1KA0 QLGQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQV .:..: :: :. :.: . : ::::: .:: .:.. XP_016 ----------KPNNQMP-VTVSI----------ANMAVSP----PPPLQ--ISPPLHQHL 380 390 400 470 480 490 500 510 pF1KA0 TILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKS-VPLPTLKMQTTLVPPTVESSPERP . .:: :: .:::: ... :.:..: . ::... :: XP_016 N-MQQHQPL-TMQQPLGNQL---------PMQVQSALHSPTMQQGFTL------------ 410 420 430 440 520 530 540 550 560 570 pF1KA0 MNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCEN .:. .:. :. : ...:... : ::::.: XP_016 ---QPDYQTIINPTS-TAAQVVTQAMEYV-------------------------RSGCRN 450 460 470 580 590 600 610 620 pF1KA0 PPIVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVVFVK :: ::.:.:::. XP_016 PPPQPVDWNNDYCSSGGMQRDKALYLT 480 490 500 >>XP_006723947 (OMIM: 611163) PREDICTED: TOX high mobili (515 aa) initn: 699 init1: 528 opt: 750 Z-score: 360.2 bits: 76.5 E(85289): 2.5e-13 Smith-Waterman score: 812; 36.2% identity (61.1% similar) in 483 aa overlap (3-477:39-480) 10 20 pF1KA0 MEFP---GGNDNYLTITGPSHPFLSGAETFHT :: :.. :. .. . .:: ..:.. XP_006 VAGAFSRCLGFCGMRLGLLLLARHWCIAGVFPQKFDGDSAYVGMSDGNPELLSTSQTYNG 10 20 30 40 50 60 30 40 50 60 70 80 pF1KA0 PSLGDEEFEIPPISLDS--DPSLA-VSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPV : ..:..:::::. . .::: ..: . . .: . . .: . : :. :..:.:. XP_006 QSENNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCH-GLTPNGLLPA-YSYQAMDLPA 70 80 90 100 110 120 90 100 110 120 130 140 pF1KA0 GMTHGLMEQGGGLLSGGLT--MDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTI :. ... : . :::: : ... :: . :... : :. . : .: .... XP_006 IMVSNMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPG----PLLGRPAMLASH--MSAL 130 140 150 160 170 180 150 160 170 180 190 200 pF1KA0 DQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVE .::.: ::.:. ..: . :: :.::::.:: .:. : . .. ..: .. XP_006 SQSQLISQMGIR---SSIAHSSPSPPGSKSATPSPSSSTQEEESE-VHFKISGEKRPSAD 190 200 210 220 230 210 220 230 240 250 260 pF1KA0 AGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSL ::: : :::.:::::::::::::::::::::::::::::::.::::.:::::::::::: XP_006 PGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSL 240 250 260 270 280 290 270 280 290 300 310 320 pF1KA0 GEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDP ::::::.:::::::::::::::::::. . : : . ..: . :: . : XP_006 GEEQKQAYKRKTEAAKKEYLKALAAYR-----ASLVSKSSPDQGETKSTQANPPAKMLPP 300 310 320 330 340 350 330 340 350 360 370 380 pF1KA0 ASPAPASIEPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQG .: : :.:. :... : :... :::. .... . .:..:: XP_006 KQPMYAM---PGLA-SFLTPSDLQAF-----RSGAS-PASLARTLGSKSLLP-------- 360 370 380 390 390 400 410 420 430 440 pF1KA0 GMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPRLQ :. . : : :. . .. : :. ... : .. : . :: : XP_006 GLSASPPPP--PSFPLSPTLHQQLSLPPHAQGALLSPPVSMSPAPQPPV----LPTPMAL 400 410 420 430 440 450 460 470 480 490 500 pF1KA0 PPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPLPTLKMQ : . :.:: :. ... : .. .: : XP_006 QVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGISTCSLLP 450 460 470 480 490 500 510 520 530 540 550 560 pF1KA0 TTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSGSPV XP_006 RDKSLYLT 510 621 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:37:46 2016 done: Wed Nov 2 19:37:47 2016 Total Scan time: 10.160 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]