Result of FASTA (omim) for
pF1KA0739
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0739, 1071 aa
1>>>pF1KA0739 1071 - 1071 aa - 1071 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3122+/-0.000453; mu= 22.8137+/- 0.028
mean_var=86.9554+/-17.950, 0's: 0 Z-trim(111.7): 112 B-trim: 304 in 1/49
Lambda= 0.137539
statistics sampled from 20308 (20421) to 20308 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.589), E-opt: 0.2 (0.239), width: 16
Scan time: 14.010
The best scores are: opt bits E(85289)
XP_016875730 (OMIM: 605024) PREDICTED: electroneut (1071) 7236 1447.0 0
NP_001035049 (OMIM: 605024) electroneutral sodium (1093) 6829 1366.2 0
NP_001245330 (OMIM: 605024) electroneutral sodium (1040) 6583 1317.4 0
XP_011537312 (OMIM: 605024) PREDICTED: electroneut (1111) 6134 1228.3 0
XP_016875729 (OMIM: 605024) PREDICTED: electroneut (1099) 5956 1193.0 0
XP_011537313 (OMIM: 605024) PREDICTED: electroneut (1058) 5888 1179.5 0
XP_016875731 (OMIM: 605024) PREDICTED: electroneut (1058) 5888 1179.5 0
XP_016860039 (OMIM: 605556) PREDICTED: sodium-driv (1098) 5600 1122.3 0
XP_016860033 (OMIM: 605556) PREDICTED: sodium-driv (1085) 5597 1121.7 0
XP_016860031 (OMIM: 605556) PREDICTED: sodium-driv (1087) 5597 1121.7 0
XP_011509814 (OMIM: 605556) PREDICTED: sodium-driv (1105) 5597 1121.8 0
NP_001171487 (OMIM: 605556) sodium-driven chloride (1099) 5588 1120.0 0
XP_005246752 (OMIM: 605556) PREDICTED: sodium-driv (1117) 5588 1120.0 0
XP_016860032 (OMIM: 605556) PREDICTED: sodium-driv (1086) 5585 1119.4 0
NP_071341 (OMIM: 605556) sodium-driven chloride bi (1088) 5585 1119.4 0
XP_011509813 (OMIM: 605556) PREDICTED: sodium-driv (1106) 5585 1119.4 0
XP_016860038 (OMIM: 605556) PREDICTED: sodium-driv (1100) 5574 1117.2 0
XP_016860035 (OMIM: 605556) PREDICTED: sodium-driv (1118) 5574 1117.2 0
XP_005265657 (OMIM: 603353) PREDICTED: sodium bica (1113) 5159 1034.8 0
XP_016863016 (OMIM: 603353) PREDICTED: sodium bica (1118) 5159 1034.8 0
XP_011532565 (OMIM: 603353) PREDICTED: sodium bica (1122) 5159 1034.8 0
XP_006719763 (OMIM: 605024) PREDICTED: electroneut ( 800) 4810 965.5 0
XP_016860042 (OMIM: 605556) PREDICTED: sodium-driv ( 895) 4659 935.5 0
XP_016860041 (OMIM: 605556) PREDICTED: sodium-driv ( 913) 4659 935.6 0
NP_001245332 (OMIM: 605024) electroneutral sodium ( 747) 4564 916.6 0
NP_001245331 (OMIM: 605024) electroneutral sodium ( 691) 4413 886.6 0
XP_016860040 (OMIM: 605556) PREDICTED: sodium-driv ( 943) 4309 866.1 0
XP_011509812 (OMIM: 605556) PREDICTED: sodium-driv (1116) 4309 866.2 0
XP_016860030 (OMIM: 605556) PREDICTED: sodium-driv (1117) 4309 866.2 0
NP_001171486 (OMIM: 605556) sodium-driven chloride (1118) 4309 866.2 0
XP_016860037 (OMIM: 605556) PREDICTED: sodium-driv (1127) 4309 866.2 0
XP_016860036 (OMIM: 605556) PREDICTED: sodium-driv (1129) 4309 866.2 0
XP_016860034 (OMIM: 605556) PREDICTED: sodium-driv (1130) 4309 866.2 0
XP_011509811 (OMIM: 605556) PREDICTED: sodium-driv (1135) 4309 866.2 0
XP_011509810 (OMIM: 605556) PREDICTED: sodium-driv (1136) 4309 866.2 0
XP_005246751 (OMIM: 605556) PREDICTED: sodium-driv (1147) 4309 866.2 0
XP_011509815 (OMIM: 605556) PREDICTED: sodium-driv (1148) 4309 866.2 0
NP_001254544 (OMIM: 605024) electroneutral sodium ( 638) 4167 837.8 0
NP_001245309 (OMIM: 603353) sodium bicarbonate cot (1090) 4153 835.2 0
NP_001308036 (OMIM: 603353) sodium bicarbonate cot (1095) 4153 835.2 0
XP_011532567 (OMIM: 603353) PREDICTED: sodium bica (1099) 4153 835.2 0
XP_005265655 (OMIM: 603353) PREDICTED: sodium bica (1126) 4153 835.2 0
NP_001245308 (OMIM: 603353) sodium bicarbonate cot (1131) 4153 835.2 0
XP_016863015 (OMIM: 603353) PREDICTED: sodium bica (1135) 4153 835.2 0
NP_001308037 (OMIM: 603353) sodium bicarbonate cot (1135) 4153 835.2 0
XP_011532563 (OMIM: 603353) PREDICTED: sodium bica (1201) 4153 835.3 0
NP_001308035 (OMIM: 603353) sodium bicarbonate cot (1206) 4153 835.3 0
NP_001308034 (OMIM: 603353) sodium bicarbonate cot (1210) 4153 835.3 0
NP_003606 (OMIM: 603353) sodium bicarbonate cotran (1214) 4153 835.3 0
XP_011532560 (OMIM: 603353) PREDICTED: sodium bica (1223) 4153 835.3 0
>>XP_016875730 (OMIM: 605024) PREDICTED: electroneutral (1071 aa)
initn: 7236 init1: 7236 opt: 7236 Z-score: 7756.7 bits: 1447.0 E(85289): 0
Smith-Waterman score: 7236; 100.0% identity (100.0% similar) in 1071 aa overlap (1-1071:1-1071)
10 20 30 40 50 60
pF1KA0 MFNKNNSNKLRSTPRYRRGDPGYLNFTELGPLKPEQKDQWSQHRPDEEAVVDQGGTSTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFNKNNSNKLRSTPRYRRGDPGYLNFTELGPLKPEQKDQWSQHRPDEEAVVDQGGTSTIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 VNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 PIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 TVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 GLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIES
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 LFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 CIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 YYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYTPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYTPD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 VLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 KLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEH
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 KLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGM
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 PAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KA0 LCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEVIVLAPTVYLGASNYRT
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEVIVLAPTVYLGASNYRT
1030 1040 1050 1060 1070
>>NP_001035049 (OMIM: 605024) electroneutral sodium bica (1093 aa)
initn: 6829 init1: 6829 opt: 6829 Z-score: 7320.2 bits: 1366.2 E(85289): 0
Smith-Waterman score: 6829; 99.8% identity (99.9% similar) in 1014 aa overlap (41-1054:14-1027)
20 30 40 50 60 70
pF1KA0 RSTPRYRRGDPGYLNFTELGPLKPEQKDQWSQHRPDEEAVVDQGGTSTILNIHYEKEELE
: .:::::::::::::::::::::::::::
NP_001 MPAAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELE
10 20 30 40
80 90 100 110 120 130
pF1KA0 GHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFIL
50 60 70 80 90 100
140 150 160 170 180 190
pF1KA0 GTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSL
110 120 130 140 150 160
200 210 220 230 240 250
pF1KA0 HSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQ
170 180 190 200 210 220
260 270 280 290 300 310
pF1KA0 NEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDL
230 240 250 260 270 280
320 330 340 350 360 370
pF1KA0 SKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFIL
290 300 310 320 330 340
380 390 400 410 420 430
pF1KA0 LGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDP
350 360 370 380 390 400
440 450 460 470 480 490
pF1KA0 SIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGLVLDIKRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGLVLDIKRKA
410 420 430 440 450 460
500 510 520 530 540 550
pF1KA0 PWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIA
470 480 490 500 510 520
560 570 580 590 600 610
pF1KA0 YSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDAS
530 540 550 560 570 580
620 630 640 650 660 670
pF1KA0 SLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPEN
590 600 610 620 630 640
680 690 700 710 720 730
pF1KA0 PNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFF
650 660 670 680 690 700
740 750 760 770 780 790
pF1KA0 TTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKP
710 720 730 740 750 760
800 810 820 830 840 850
pF1KA0 TRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHL
770 780 790 800 810 820
860 870 880 890 900 910
pF1KA0 DLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGL
830 840 850 860 870 880
920 930 940 950 960 970
pF1KA0 MIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIY
890 900 910 920 930 940
980 990 1000 1010 1020 1030
pF1KA0 LRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSW
950 960 970 980 990 1000
1040 1050 1060 1070
pF1KA0 LDDLMPESKKKKLDDAKKKAKEEEVIVLAPTVYLGASNYRT
::::::::::::::::::::::::
NP_001 LDDLMPESKKKKLDDAKKKAKEEEEAEKMLEIGGDKFPLESRKLLSSPGKNISCRCDPSE
1010 1020 1030 1040 1050 1060
>>NP_001245330 (OMIM: 605024) electroneutral sodium bica (1040 aa)
initn: 6583 init1: 6583 opt: 6583 Z-score: 7056.6 bits: 1317.4 E(85289): 0
Smith-Waterman score: 6583; 100.0% identity (100.0% similar) in 974 aa overlap (81-1054:1-974)
60 70 80 90 100 110
pF1KA0 VDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQG
::::::::::::::::::::::::::::::
NP_001 MPLGRQSHRHHRTHGQKHRRRGRGKGASQG
10 20 30
120 130 140 150 160 170
pF1KA0 EEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA0 EDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSD
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA0 LNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSV
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA0 PTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSP
220 230 240 250 260 270
360 370 380 390 400 410
pF1KA0 AVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLL
280 290 300 310 320 330
420 430 440 450 460 470
pF1KA0 AGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGP
340 350 360 370 380 390
480 490 500 510 520 530
pF1KA0 ELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEA
400 410 420 430 440 450
540 550 560 570 580 590
pF1KA0 TEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLR
460 470 480 490 500 510
600 610 620 630 640 650
pF1KA0 ACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIH
520 530 540 550 560 570
660 670 680 690 700 710
pF1KA0 MHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSA
580 590 600 610 620 630
720 730 740 750 760 770
pF1KA0 CGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVI
640 650 660 670 680 690
780 790 800 810 820 830
pF1KA0 IDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQI
700 710 720 730 740 750
840 850 860 870 880 890
pF1KA0 TAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESEC
760 770 780 790 800 810
900 910 920 930 940 950
pF1KA0 SAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQ
820 830 840 850 860 870
960 970 980 990 1000 1010
pF1KA0 FFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVL
880 890 900 910 920 930
1020 1030 1040 1050 1060 1070
pF1KA0 ALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEVIVLAPTVYLGASNYR
::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEEAEKMLEIGGDKFPLE
940 950 960 970 980 990
pF1KA0 T
NP_001 SRKLLSSPGKNISCRCDPSEINISDEMPKTTVWKALSMNSGNAKEKSLFN
1000 1010 1020 1030 1040
>>XP_011537312 (OMIM: 605024) PREDICTED: electroneutral (1111 aa)
initn: 6165 init1: 6134 opt: 6134 Z-score: 6574.8 bits: 1228.3 E(85289): 0
Smith-Waterman score: 6783; 98.1% identity (98.2% similar) in 1032 aa overlap (41-1054:14-1045)
20 30 40 50 60 70
pF1KA0 RSTPRYRRGDPGYLNFTELGPLKPEQKDQWSQHRPDEEAVVDQGGTSTILNIHYEKEELE
: .:::::::::::::::::::::::::::
XP_011 MPAAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELE
10 20 30 40
80 90 100 110 120 130
pF1KA0 GHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFIL
50 60 70 80 90 100
140 150 160 170 180 190
pF1KA0 GTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSL
110 120 130 140 150 160
200 210 220 230 240 250
pF1KA0 HSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQ
170 180 190 200 210 220
260 270 280 290 300 310
pF1KA0 NEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDL
230 240 250 260 270 280
320 330 340 350 360 370
pF1KA0 SKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFIL
290 300 310 320 330 340
380 390 400 410 420 430
pF1KA0 LGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDP
350 360 370 380 390 400
440 450 460 470 480 490
pF1KA0 SIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGLVLDIKRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGLVLDIKRKA
410 420 430 440 450 460
500 510 520 530 540 550
pF1KA0 PWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIA
470 480 490 500 510 520
560 570 580 590 600 610
pF1KA0 YSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDAS
530 540 550 560 570 580
620 630 640 650 660 670
pF1KA0 SLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPEN
590 600 610 620 630 640
680 690 700 710 720 730
pF1KA0 PNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFF
650 660 670 680 690 700
740 750 760 770 780 790
pF1KA0 TTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKP
710 720 730 740 750 760
800 810 820 830 840 850
pF1KA0 TRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHL
770 780 790 800 810 820
860 870 880 890 900 910
pF1KA0 DLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGL
830 840 850 860 870 880
920 930 940 950
pF1KA0 MIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQ------------------FF
:::::::::::::::::::::::::::::::::::::::: ::
XP_011 MIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQSQFPFLSRGNGVTYLSEQFF
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KA0 DRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLAL
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
pF1KA0 VFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEVIVLAPTVYLGASNYRT
::::::::::::::::::::::::::::::::::::::::::
XP_011 VFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEEAEKMLEIGGDKFPLESR
1010 1020 1030 1040 1050 1060
XP_011 KLLSSPGKNISCRCDPSEINISDEMPKTTVWKALSMNSGNAKEKSLFN
1070 1080 1090 1100 1110
>>XP_016875729 (OMIM: 605024) PREDICTED: electroneutral (1099 aa)
initn: 5987 init1: 5956 opt: 5956 Z-score: 6383.9 bits: 1193.0 E(85289): 0
Smith-Waterman score: 6605; 98.2% identity (98.2% similar) in 1002 aa overlap (71-1054:32-1033)
50 60 70 80 90 100
pF1KA0 SQHRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRR
::::::::::::::::::::::::::::::
XP_016 KKLWWIRVGPVQFSTFTMKKKSWKTFCFFPGHRTLYVGVRMPLGRQSHRHHRTHGQKHRR
10 20 30 40 50 60
110 120 130 140 150 160
pF1KA0 RGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEW
70 80 90 100 110 120
170 180 190 200 210 220
pF1KA0 KETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDL
130 140 150 160 170 180
230 240 250 260 270 280
pF1KA0 ILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDK
190 200 210 220 230 240
290 300 310 320 330 340
pF1KA0 HGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDR
250 260 270 280 290 300
350 360 370 380 390 400
pF1KA0 PIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVA
310 320 330 340 350 360
410 420 430 440 450 460
pF1KA0 YKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIE
370 380 390 400 410 420
470 480 490 500 510 520
pF1KA0 QEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPV
430 440 450 460 470 480
530 540 550 560 570 580
pF1KA0 ITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCK
490 500 510 520 530 540
590 600 610 620 630 640
pF1KA0 DYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKL
550 560 570 580 590 600
650 660 670 680 690 700
pF1KA0 IHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQ
610 620 630 640 650 660
710 720 730 740 750 760
pF1KA0 EMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFA
670 680 690 700 710 720
770 780 790 800 810 820
pF1KA0 VFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLC
730 740 750 760 770 780
830 840 850 860 870 880
pF1KA0 TILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITH
790 800 810 820 830 840
890 900 910 920 930 940
pF1KA0 VNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLY
850 860 870 880 890 900
950 960 970 980
pF1KA0 MGVSSLQGIQ------------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLF
:::::::::: ::::::::::::::::::::::::::::::::
XP_016 MGVSSLQGIQSQFPFLSRGNGVTYLSEQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLF
910 920 930 940 950 960
990 1000 1010 1020 1030 1040
pF1KA0 TLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKK
970 980 990 1000 1010 1020
1050 1060 1070
pF1KA0 LDDAKKKAKEEEVIVLAPTVYLGASNYRT
::::::::::::
XP_016 LDDAKKKAKEEEEAEKMLEIGGDKFPLESRKLLSSPGKNISCRCDPSEINISDEMPKTTV
1030 1040 1050 1060 1070 1080
>>XP_011537313 (OMIM: 605024) PREDICTED: electroneutral (1058 aa)
initn: 5919 init1: 5888 opt: 5888 Z-score: 6311.2 bits: 1179.5 E(85289): 0
Smith-Waterman score: 6537; 98.2% identity (98.2% similar) in 992 aa overlap (81-1054:1-992)
60 70 80 90 100 110
pF1KA0 VDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQG
::::::::::::::::::::::::::::::
XP_011 MPLGRQSHRHHRTHGQKHRRRGRGKGASQG
10 20 30
120 130 140 150 160 170
pF1KA0 EEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA0 EDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSD
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA0 LNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSV
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA0 PTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSP
220 230 240 250 260 270
360 370 380 390 400 410
pF1KA0 AVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLL
280 290 300 310 320 330
420 430 440 450 460 470
pF1KA0 AGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGP
340 350 360 370 380 390
480 490 500 510 520 530
pF1KA0 ELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEA
400 410 420 430 440 450
540 550 560 570 580 590
pF1KA0 TEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLR
460 470 480 490 500 510
600 610 620 630 640 650
pF1KA0 ACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIH
520 530 540 550 560 570
660 670 680 690 700 710
pF1KA0 MHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSA
580 590 600 610 620 630
720 730 740 750 760 770
pF1KA0 CGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVI
640 650 660 670 680 690
780 790 800 810 820 830
pF1KA0 IDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQI
700 710 720 730 740 750
840 850 860 870 880 890
pF1KA0 TAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESEC
760 770 780 790 800 810
900 910 920 930 940 950
pF1KA0 SAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQ
820 830 840 850 860 870
960 970 980 990
pF1KA0 ------------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVL
::::::::::::::::::::::::::::::::::::::::::
XP_011 SQFPFLSRGNGVTYLSEQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVL
880 890 900 910 920 930
1000 1010 1020 1030 1040 1050
pF1KA0 LWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKE
940 950 960 970 980 990
1060 1070
pF1KA0 EEVIVLAPTVYLGASNYRT
::
XP_011 EEEAEKMLEIGGDKFPLESRKLLSSPGKNISCRCDPSEINISDEMPKTTVWKALSMNSGN
1000 1010 1020 1030 1040 1050
>>XP_016875731 (OMIM: 605024) PREDICTED: electroneutral (1058 aa)
initn: 5919 init1: 5888 opt: 5888 Z-score: 6311.2 bits: 1179.5 E(85289): 0
Smith-Waterman score: 6537; 98.2% identity (98.2% similar) in 992 aa overlap (81-1054:1-992)
60 70 80 90 100 110
pF1KA0 VDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQG
::::::::::::::::::::::::::::::
XP_016 MPLGRQSHRHHRTHGQKHRRRGRGKGASQG
10 20 30
120 130 140 150 160 170
pF1KA0 EEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA0 EDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSD
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA0 LNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSV
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA0 PTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSP
220 230 240 250 260 270
360 370 380 390 400 410
pF1KA0 AVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLL
280 290 300 310 320 330
420 430 440 450 460 470
pF1KA0 AGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGP
340 350 360 370 380 390
480 490 500 510 520 530
pF1KA0 ELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEA
400 410 420 430 440 450
540 550 560 570 580 590
pF1KA0 TEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLR
460 470 480 490 500 510
600 610 620 630 640 650
pF1KA0 ACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIH
520 530 540 550 560 570
660 670 680 690 700 710
pF1KA0 MHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSA
580 590 600 610 620 630
720 730 740 750 760 770
pF1KA0 CGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVI
640 650 660 670 680 690
780 790 800 810 820 830
pF1KA0 IDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQI
700 710 720 730 740 750
840 850 860 870 880 890
pF1KA0 TAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESEC
760 770 780 790 800 810
900 910 920 930 940 950
pF1KA0 SAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQ
820 830 840 850 860 870
960 970 980 990
pF1KA0 ------------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVL
::::::::::::::::::::::::::::::::::::::::::
XP_016 SQFPFLSRGNGVTYLSEQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVL
880 890 900 910 920 930
1000 1010 1020 1030 1040 1050
pF1KA0 LWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKE
940 950 960 970 980 990
1060 1070
pF1KA0 EEVIVLAPTVYLGASNYRT
::
XP_016 EEEAEKMLEIGGDKFPLESRKLLSSPGKNISCRCDPSEINISDEMPKTTVWKALSMNSGN
1000 1010 1020 1030 1040 1050
>>XP_016860039 (OMIM: 605556) PREDICTED: sodium-driven c (1098 aa)
initn: 5510 init1: 4558 opt: 5600 Z-score: 6002.2 bits: 1122.3 E(85289): 0
Smith-Waterman score: 5600; 78.8% identity (92.3% similar) in 1043 aa overlap (19-1059:5-1040)
10 20 30 40 50 60
pF1KA0 MFNKNNSNKLRSTPRYRRGDPGYLNFTELGPLKPEQKDQWSQHRPDEEAVVDQGGTSTIL
: : . . : .: : . :..: :::::::.::: .::
XP_016 MQSLGVSGNRKVMQSGTCEPFQ--SLSHQRNDEEAVVDRGGTRSIL
10 20 30 40
70 80 90 100 110
pF1KA0 NIHYEKEELEGHRTLYVGVRMPLG-RQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAH
. :.:::.:::::::..::..::: :.:::.:: .:.:::.: : . : :.: :. .
XP_016 KTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERD-SGLEDGRESPSF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KA0 DTPSQRVQFILGTEED-EEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGE
::::::::::::::.: :::.::.::::::::: .:::::::.:::::::::::::::::
XP_016 DTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KA0 RWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVK
:::::::::::::::::::::..:::::::::::..:::.:..:::: :..::...: .
XP_016 RWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHR
170 180 190 200 210 220
240 250 260 270 280 290
pF1KA0 VREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVK
:.:::.:.:::::.:: .: ::::::::..:::::.:. :::.::.:::::.:. .: :
XP_016 VHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNGQVVSPQSAPAC-VENK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KA0 NGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLT
: :. :.: ::.:::::::::::: ::::::.::::...::: .::::::::::::.::.
XP_016 NDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLA
290 300 310 320 330 340
360 370 380 390 400 410
pF1KA0 EVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLD
:::::::::::::::.::::::::::::.::.::::.:::::::::.:.::..:::::::
XP_016 EVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLD
350 360 370 380 390 400
420 430 440 450 460 470
pF1KA0 QVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGRL
:::::::::::::::::::::::::::::.:.::::.. : : ::::::::::::::::.
XP_016 QVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSGPELQRTGRI
410 420 430 440 450 460
480 490 500 510 520 530
pF1KA0 FGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAI
::::.::::::::..:::.:::.:::::::::::::::::::::::::::::::::::::
XP_016 FGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAI
470 480 490 500 510 520
540 550 560 570 580 590
pF1KA0 ESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTA
::::::::::::::::.:: ::::::::::::::::::::::.:.:::::::: ::::::
XP_016 ESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTA
530 540 550 560 570 580
600 610 620 630 640 650
pF1KA0 FLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHL
:::.:::::::::::::::::::::::::::::::::.:::..:.:.:::.::..:. :
XP_016 TLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELL
590 600 610 620 630 640
660 670 680 690 700 710
pF1KA0 SLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYT
. : : :. :.::.: ::. :.. :: .... : :::::::. .:::..: :::: ::.
XP_016 TQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDHPYV
650 660 670 680 690 700
720 730 740 750 760 770
pF1KA0 PDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVP
::::::: ::::.: ::.::: :::::::::.:::.::::::::::. ::.::. ::.:
XP_016 PDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIP
710 720 730 740 750 760
780 790 800 810 820 830
pF1KA0 SPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRK
:::::::::::::::::::...:.::::::::::::::::::::::::::::::::::::
XP_016 SPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRK
770 780 790 800 810 820
840 850 860 870 880 890
pF1KA0 EHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPK
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_016 EHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPK
830 840 850 860 870 880
900 910 920 930 940 950
pF1KA0 FLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLF
:::::::::::::::.::: :::::.::::::::::::::::::.:::.:::::::.:::
XP_016 FLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLF
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KA0 GMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKV
::::::::::::::::::::::::.::..:: :::.::.: :::::::::::::::::.
XP_016 WMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKL
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
pF1KA0 MDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEVIVLAPTVYLGASNYRT
::: :.:::::::::::::::::::.::. :::: .::
XP_016 MDLLFTKRELSWLDDLMPESKKKKLEDAE---KEEEQSMLAMEDEGTVQLPLEGHYRDDP
1010 1020 1030 1040 1050
XP_016 SVINISDEMSKTALWRNLLITADNSKDKESSFPSKSSPS
1060 1070 1080 1090
>>XP_016860033 (OMIM: 605556) PREDICTED: sodium-driven c (1085 aa)
initn: 5510 init1: 4558 opt: 5597 Z-score: 5999.0 bits: 1121.7 E(85289): 0
Smith-Waterman score: 5597; 79.5% identity (92.7% similar) in 1033 aa overlap (35-1059:2-1029)
10 20 30 40 50
pF1KA0 NNSNKLRSTPRYRRGDPGYLNFTELGPLKPEQKDQWSQHRP------DEEAVVDQGGTST
: ::: .: .: :::::::.::: .
XP_016 MEIKDQGAQMEPLLPTRNDEEAVVDRGGTRS
10 20 30
60 70 80 90 100 110
pF1KA0 ILNIHYEKEELEGHRTLYVGVRMPLG-RQSHRHHRTHGQKHRRRGRGKGASQGEEGLEAL
::. :.:::.:::::::..::..::: :.:::.:: .:.:::.: : . : :.: :.
XP_016 ILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERD-SGLEDGRESP
40 50 60 70 80 90
120 130 140 150 160 170
pF1KA0 AHDTPSQRVQFILGTEED-EEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDG
. ::::::::::::::.: :::.::.::::::::: .:::::::.:::::::::::::::
XP_016 SFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KA0 GERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMR
:::::::::::::::::::::::..:::::::::::..:::.:..:::: :..::...:
XP_016 GERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVR
160 170 180 190 200 210
240 250 260 270 280 290
pF1KA0 VKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLE
.:.:::.:.:::::.:: .: ::::::::..:::::.:. :::.::.:::::.:. .:
XP_016 HRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNGQVVSPQSAPAC-VE
220 230 240 250 260
300 310 320 330 340 350
pF1KA0 VKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSG
:: :. :.: ::.:::::::::::: ::::::.::::...::: .::::::::::::.:
XP_016 NKNDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQG
270 280 290 300 310 320
360 370 380 390 400 410
pF1KA0 LTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEF
:.:::::::::::::::.::::::::::::.::.::::.:::::::::.:.::..:::::
XP_016 LAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEF
330 340 350 360 370 380
420 430 440 450 460 470
pF1KA0 LDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTG
:::::::::::::::::::::::::::::::.:.::::.. : : :::::::::::::::
XP_016 LDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSGPELQRTG
390 400 410 420 430 440
480 490 500 510 520 530
pF1KA0 RLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRIS
:.::::.::::::::..:::.:::.:::::::::::::::::::::::::::::::::::
XP_016 RIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRIS
450 460 470 480 490 500
540 550 560 570 580 590
pF1KA0 AIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLW
::::::::::::::::::.:: ::::::::::::::::::::::.:.:::::::: ::::
XP_016 AIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLW
510 520 530 540 550 560
600 610 620 630 640 650
pF1KA0 TAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLD
:: :::.:::::::::::::::::::::::::::::::::.:::..:.:.:::.::..:.
XP_016 TATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLE
570 580 590 600 610 620
660 670 680 690 700 710
pF1KA0 HLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGP
:. : : :. :.::.: ::. :.. :: .... : :::::::. .:::..: :::: :
XP_016 LLTQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDHP
630 640 650 660 670 680
720 730 740 750 760 770
pF1KA0 YTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIG
:.::::::: ::::.: ::.::: :::::::::.:::.::::::::::. ::.::. ::
XP_016 YVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIG
690 700 710 720 730 740
780 790 800 810 820 830
pF1KA0 VPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIIN
.::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
XP_016 IPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIIN
750 760 770 780 790 800
840 850 860 870 880 890
pF1KA0 RKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_016 RKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ
810 820 830 840 850 860
900 910 920 930 940 950
pF1KA0 PKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLK
:::::::::::::::::.::: :::::.::::::::::::::::::.:::.:::::::.:
XP_016 PKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIK
870 880 890 900 910 920
960 970 980 990 1000 1010
pF1KA0 LFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVR
:: ::::::::::::::::::::::::.::..:: :::.::.: ::::::::::::::::
XP_016 LFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVR
930 940 950 960 970 980
1020 1030 1040 1050 1060 1070
pF1KA0 KVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEVIVLAPTVYLGASNYRT
:.::: :.:::::::::::::::::::.::. :::: .::
XP_016 KLMDLLFTKRELSWLDDLMPESKKKKLEDAE---KEEEQSMLAMEDEGTVQLPLEGHYRD
990 1000 1010 1020 1030 1040
XP_016 DPSVINISDEMSKTALWRNLLITADNSKDKESSFPSKRS
1050 1060 1070 1080
>>XP_016860031 (OMIM: 605556) PREDICTED: sodium-driven c (1087 aa)
initn: 5510 init1: 4558 opt: 5597 Z-score: 5999.0 bits: 1121.7 E(85289): 0
Smith-Waterman score: 5597; 79.5% identity (92.7% similar) in 1033 aa overlap (35-1059:2-1029)
10 20 30 40 50
pF1KA0 NNSNKLRSTPRYRRGDPGYLNFTELGPLKPEQKDQWSQHRP------DEEAVVDQGGTST
: ::: .: .: :::::::.::: .
XP_016 MEIKDQGAQMEPLLPTRNDEEAVVDRGGTRS
10 20 30
60 70 80 90 100 110
pF1KA0 ILNIHYEKEELEGHRTLYVGVRMPLG-RQSHRHHRTHGQKHRRRGRGKGASQGEEGLEAL
::. :.:::.:::::::..::..::: :.:::.:: .:.:::.: : . : :.: :.
XP_016 ILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERD-SGLEDGRESP
40 50 60 70 80 90
120 130 140 150 160 170
pF1KA0 AHDTPSQRVQFILGTEED-EEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDG
. ::::::::::::::.: :::.::.::::::::: .:::::::.:::::::::::::::
XP_016 SFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KA0 GERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMR
:::::::::::::::::::::::..:::::::::::..:::.:..:::: :..::...:
XP_016 GERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVR
160 170 180 190 200 210
240 250 260 270 280 290
pF1KA0 VKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLE
.:.:::.:.:::::.:: .: ::::::::..:::::.:. :::.::.:::::.:. .:
XP_016 HRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNGQVVSPQSAPAC-VE
220 230 240 250 260
300 310 320 330 340 350
pF1KA0 VKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSG
:: :. :.: ::.:::::::::::: ::::::.::::...::: .::::::::::::.:
XP_016 NKNDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQG
270 280 290 300 310 320
360 370 380 390 400 410
pF1KA0 LTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEF
:.:::::::::::::::.::::::::::::.::.::::.:::::::::.:.::..:::::
XP_016 LAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEF
330 340 350 360 370 380
420 430 440 450 460 470
pF1KA0 LDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTG
:::::::::::::::::::::::::::::::.:.::::.. : : :::::::::::::::
XP_016 LDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSGPELQRTG
390 400 410 420 430 440
480 490 500 510 520 530
pF1KA0 RLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRIS
:.::::.::::::::..:::.:::.:::::::::::::::::::::::::::::::::::
XP_016 RIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRIS
450 460 470 480 490 500
540 550 560 570 580 590
pF1KA0 AIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLW
::::::::::::::::::.:: ::::::::::::::::::::::.:.:::::::: ::::
XP_016 AIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLW
510 520 530 540 550 560
600 610 620 630 640 650
pF1KA0 TAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLD
:: :::.:::::::::::::::::::::::::::::::::.:::..:.:.:::.::..:.
XP_016 TATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLE
570 580 590 600 610 620
660 670 680 690 700 710
pF1KA0 HLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGP
:. : : :. :.::.: ::. :.. :: .... : :::::::. .:::..: :::: :
XP_016 LLTQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDHP
630 640 650 660 670 680
720 730 740 750 760 770
pF1KA0 YTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIG
:.::::::: ::::.: ::.::: :::::::::.:::.::::::::::. ::.::. ::
XP_016 YVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIG
690 700 710 720 730 740
780 790 800 810 820 830
pF1KA0 VPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIIN
.::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
XP_016 IPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIIN
750 760 770 780 790 800
840 850 860 870 880 890
pF1KA0 RKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_016 RKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ
810 820 830 840 850 860
900 910 920 930 940 950
pF1KA0 PKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLK
:::::::::::::::::.::: :::::.::::::::::::::::::.:::.:::::::.:
XP_016 PKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIK
870 880 890 900 910 920
960 970 980 990 1000 1010
pF1KA0 LFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVR
:: ::::::::::::::::::::::::.::..:: :::.::.: ::::::::::::::::
XP_016 LFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVR
930 940 950 960 970 980
1020 1030 1040 1050 1060 1070
pF1KA0 KVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEVIVLAPTVYLGASNYRT
:.::: :.:::::::::::::::::::.::. :::: .::
XP_016 KLMDLLFTKRELSWLDDLMPESKKKKLEDAE---KEEEQSMLAMEDEGTVQLPLEGHYRD
990 1000 1010 1020 1030 1040
XP_016 DPSVINISDEMSKTALWRNLLITADNSKDKESSFPSKSSPS
1050 1060 1070 1080
1071 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:14:22 2016 done: Thu Nov 3 10:14:25 2016
Total Scan time: 14.010 Total Display time: 0.490
Function used was FASTA [36.3.4 Apr, 2011]