Result of FASTA (omim) for
pF1KA0751
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0751, 1188 aa
1>>>pF1KA0751 1188 - 1188 aa - 1188 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.2968+/-0.000427; mu= -0.7391+/- 0.027
mean_var=298.1043+/-62.100, 0's: 0 Z-trim(119.5): 224 B-trim: 157 in 1/54
Lambda= 0.074283
statistics sampled from 33246 (33512) to 33246 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.393), width: 16
Scan time: 18.010
The best scores are: opt bits E(85289)
NP_001269810 (OMIM: 606630) regulating synaptic me (1188) 7951 867.0 0
XP_016869514 (OMIM: 606630) PREDICTED: regulating (1438) 7682 838.2 0
XP_016869515 (OMIM: 606630) PREDICTED: regulating (1420) 7681 838.1 0
XP_016869500 (OMIM: 606630) PREDICTED: regulating (1621) 6163 675.5 7.6e-193
XP_016869495 (OMIM: 606630) PREDICTED: regulating (1705) 6163 675.5 7.9e-193
XP_016869502 (OMIM: 606630) PREDICTED: regulating (1607) 6162 675.3 8.2e-193
XP_016869501 (OMIM: 606630) PREDICTED: regulating (1610) 6139 672.9 4.5e-192
XP_005251164 (OMIM: 606630) PREDICTED: regulating (1552) 6138 672.8 4.7e-192
XP_016869532 (OMIM: 606630) PREDICTED: regulating (1210) 5799 636.3 3.4e-181
XP_016869511 (OMIM: 606630) PREDICTED: regulating (1477) 5797 636.2 4.6e-181
XP_005251163 (OMIM: 606630) PREDICTED: regulating (1574) 5540 608.7 9.4e-173
XP_016869519 (OMIM: 606630) PREDICTED: regulating (1402) 5529 607.5 1.9e-172
XP_016869518 (OMIM: 606630) PREDICTED: regulating (1406) 5529 607.5 1.9e-172
XP_016869512 (OMIM: 606630) PREDICTED: regulating (1471) 5528 607.4 2.2e-172
XP_016869534 (OMIM: 606630) PREDICTED: regulating (1141) 5221 574.4 1.4e-162
XP_016869527 (OMIM: 606630) PREDICTED: regulating (1333) 5221 574.4 1.6e-162
XP_016869526 (OMIM: 606630) PREDICTED: regulating (1337) 5221 574.4 1.6e-162
XP_016869522 (OMIM: 606630) PREDICTED: regulating (1377) 5221 574.4 1.7e-162
XP_016869521 (OMIM: 606630) PREDICTED: regulating (1391) 5221 574.5 1.7e-162
XP_016869533 (OMIM: 606630) PREDICTED: regulating (1157) 4117 456.1 6e-127
NP_001093587 (OMIM: 606630) regulating synaptic me (1349) 4118 456.2 6.2e-127
XP_016869517 (OMIM: 606630) PREDICTED: regulating (1407) 4118 456.3 6.4e-127
XP_016869513 (OMIM: 606630) PREDICTED: regulating (1454) 4078 452.0 1.3e-125
XP_016869529 (OMIM: 606630) PREDICTED: regulating (1324) 3702 411.6 1.6e-113
XP_016869509 (OMIM: 606630) PREDICTED: regulating (1520) 3702 411.7 1.8e-113
XP_016869505 (OMIM: 606630) PREDICTED: regulating (1574) 3702 411.7 1.8e-113
XP_011515697 (OMIM: 606630) PREDICTED: regulating (1710) 3680 409.4 1e-112
XP_016869508 (OMIM: 606630) PREDICTED: regulating (1545) 3678 409.1 1.1e-112
XP_016869506 (OMIM: 606630) PREDICTED: regulating (1563) 3678 409.1 1.1e-112
XP_016869503 (OMIM: 606630) PREDICTED: regulating (1589) 3678 409.1 1.1e-112
XP_016869498 (OMIM: 606630) PREDICTED: regulating (1637) 3660 407.2 4.3e-112
XP_016869520 (OMIM: 606630) PREDICTED: regulating (1394) 3640 405.0 1.7e-111
XP_011515700 (OMIM: 606630) PREDICTED: regulating (1476) 3640 405.0 1.8e-111
XP_016869497 (OMIM: 606630) PREDICTED: regulating (1672) 3640 405.1 1.9e-111
XP_016869496 (OMIM: 606630) PREDICTED: regulating (1675) 3640 405.1 1.9e-111
XP_011533917 (OMIM: 603649,606629) PREDICTED: regu (1342) 3556 396.0 8.4e-109
XP_016866021 (OMIM: 603649,606629) PREDICTED: regu (1343) 3528 393.0 6.7e-108
XP_016866043 (OMIM: 603649,606629) PREDICTED: regu ( 816) 3521 392.1 7.7e-108
NP_001161880 (OMIM: 603649,606629) regulating syna ( 817) 3493 389.1 6.2e-107
NP_055492 (OMIM: 606630) regulating synaptic membr (1163) 3069 343.8 3.9e-93
XP_016869524 (OMIM: 606630) PREDICTED: regulating (1359) 3069 343.8 4.4e-93
XP_016869516 (OMIM: 606630) PREDICTED: regulating (1413) 3069 343.8 4.5e-93
XP_016869525 (OMIM: 606630) PREDICTED: regulating (1357) 3067 343.6 5e-93
XP_016869507 (OMIM: 606630) PREDICTED: regulating (1549) 3067 343.6 5.6e-93
XP_016869535 (OMIM: 606630) PREDICTED: regulating (1081) 3030 339.6 6.6e-92
XP_016869510 (OMIM: 606630) PREDICTED: regulating (1503) 3033 340.0 6.8e-92
XP_016869531 (OMIM: 606630) PREDICTED: regulating (1273) 3030 339.6 7.5e-92
XP_016869530 (OMIM: 606630) PREDICTED: regulating (1275) 3030 339.6 7.5e-92
XP_016869504 (OMIM: 606630) PREDICTED: regulating (1579) 2575 290.9 4.2e-77
XP_016869523 (OMIM: 606630) PREDICTED: regulating (1375) 2275 258.7 1.8e-67
>>NP_001269810 (OMIM: 606630) regulating synaptic membra (1188 aa)
initn: 7951 init1: 7951 opt: 7951 Z-score: 4620.6 bits: 867.0 E(85289): 0
Smith-Waterman score: 7951; 100.0% identity (100.0% similar) in 1188 aa overlap (1-1188:1-1188)
10 20 30 40 50 60
pF1KA0 MQFETLRQVCNSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQFETLRQVCNSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 REEYSQYATSDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REEYSQYATSDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DVESRDEYERQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVESRDEYERQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LANADLEDSRISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LANADLEDSRISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 PPTPRRSPLPIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPTPRRSPLPIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PPPPKPHKSKKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPPKPHKSKKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 EQAVLSDSNTRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQAVLSDSNTRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 PVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 GSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 DSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 VTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 REFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 SPYMPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPYMPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QVMSSNHCSPSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVMSSNHCSPSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HRVMDDHYSPDRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRVMDDHYSPDRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 MTGRSAPPSPALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRKAGGKKLRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTGRSAPPSPALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRKAGGKKLRST
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 VQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 GVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180
pF1KA0 ELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
1150 1160 1170 1180
>>XP_016869514 (OMIM: 606630) PREDICTED: regulating syna (1438 aa)
initn: 7682 init1: 7682 opt: 7682 Z-score: 4463.6 bits: 838.2 E(85289): 0
Smith-Waterman score: 7682; 99.9% identity (100.0% similar) in 1149 aa overlap (40-1188:290-1438)
10 20 30 40 50 60
pF1KA0 CNSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREEREEYSQYAT
.:::::::::::::::::::::::::::::
XP_016 KNGSGVKHHIASDIASDRKTSSELLNSKIISRKRSPSVSRDQNRRYDQREEREEYSQYAT
260 270 280 290 300 310
70 80 90 100 110 120
pF1KA0 SDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYE
320 330 340 350 360 370
130 140 150 160 170 180
pF1KA0 RQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDS
380 390 400 410 420 430
190 200 210 220 230 240
pF1KA0 RISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPL
440 450 460 470 480 490
250 260 270 280 290 300
pF1KA0 PIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKS
500 510 520 530 540 550
310 320 330 340 350 360
pF1KA0 KKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSN
560 570 580 590 600 610
370 380 390 400 410 420
pF1KA0 TRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKD
620 630 640 650 660 670
430 440 450 460 470 480
pF1KA0 GDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGH
680 690 700 710 720 730
490 500 510 520 530 540
pF1KA0 LRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLES
740 750 760 770 780 790
550 560 570 580 590 600
pF1KA0 SSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDL
800 810 820 830 840 850
610 620 630 640 650 660
pF1KA0 PSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLE
860 870 880 890 900 910
670 680 690 700 710 720
pF1KA0 ITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQL
920 930 940 950 960 970
730 740 750 760 770 780
pF1KA0 HGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCS
980 990 1000 1010 1020 1030
790 800 810 820 830 840
pF1KA0 PSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYS
1040 1050 1060 1070 1080 1090
850 860 870 880 890 900
pF1KA0 PDRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPS
1100 1110 1120 1130 1140 1150
910 920 930 940 950 960
pF1KA0 PALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRKAGGKKLRSTVQRSTETGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRKAGGKKLRSTVQRSTETGL
1160 1170 1180 1190 1200 1210
970 980 990 1000 1010 1020
pF1KA0 AVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQT
1220 1230 1240 1250 1260 1270
1030 1040 1050 1060 1070 1080
pF1KA0 LATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKT
1280 1290 1300 1310 1320 1330
1090 1100 1110 1120 1130 1140
pF1KA0 KVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVI
1340 1350 1360 1370 1380 1390
1150 1160 1170 1180
pF1KA0 GWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
:::::::::::::::::::::::::::::::::::::::
XP_016 GWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
1400 1410 1420 1430
>>XP_016869515 (OMIM: 606630) PREDICTED: regulating syna (1420 aa)
initn: 7681 init1: 7681 opt: 7681 Z-score: 4463.1 bits: 838.1 E(85289): 0
Smith-Waterman score: 7681; 100.0% identity (100.0% similar) in 1148 aa overlap (41-1188:273-1420)
20 30 40 50 60 70
pF1KA0 NSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREEREEYSQYATS
::::::::::::::::::::::::::::::
XP_016 KSRSHGLTRQHSIKNGSGVKHHIASDIASDRKRSPSVSRDQNRRYDQREEREEYSQYATS
250 260 270 280 290 300
80 90 100 110 120 130
pF1KA0 DTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYER
310 320 330 340 350 360
140 150 160 170 180 190
pF1KA0 QRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDSR
370 380 390 400 410 420
200 210 220 230 240 250
pF1KA0 ISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPLP
430 440 450 460 470 480
260 270 280 290 300 310
pF1KA0 IDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKSK
490 500 510 520 530 540
320 330 340 350 360 370
pF1KA0 KGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSNT
550 560 570 580 590 600
380 390 400 410 420 430
pF1KA0 RSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKDG
610 620 630 640 650 660
440 450 460 470 480 490
pF1KA0 DRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHL
670 680 690 700 710 720
500 510 520 530 540 550
pF1KA0 RPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESS
730 740 750 760 770 780
560 570 580 590 600 610
pF1KA0 SSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDLP
790 800 810 820 830 840
620 630 640 650 660 670
pF1KA0 SREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEI
850 860 870 880 890 900
680 690 700 710 720 730
pF1KA0 TLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQLH
910 920 930 940 950 960
740 750 760 770 780 790
pF1KA0 GESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCSP
970 980 990 1000 1010 1020
800 810 820 830 840 850
pF1KA0 SGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYSP
1030 1040 1050 1060 1070 1080
860 870 880 890 900 910
pF1KA0 DRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPSP
1090 1100 1110 1120 1130 1140
920 930 940 950 960 970
pF1KA0 ALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRKAGGKKLRSTVQRSTETGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRKAGGKKLRSTVQRSTETGLA
1150 1160 1170 1180 1190 1200
980 990 1000 1010 1020 1030
pF1KA0 VEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTL
1210 1220 1230 1240 1250 1260
1040 1050 1060 1070 1080 1090
pF1KA0 ATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTK
1270 1280 1290 1300 1310 1320
1100 1110 1120 1130 1140 1150
pF1KA0 VARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIG
1330 1340 1350 1360 1370 1380
1160 1170 1180
pF1KA0 WFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
::::::::::::::::::::::::::::::::::::::
XP_016 WFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
1390 1400 1410 1420
>>XP_016869500 (OMIM: 606630) PREDICTED: regulating syna (1621 aa)
initn: 6145 init1: 6145 opt: 6163 Z-score: 3583.1 bits: 675.5 E(85289): 7.6e-193
Smith-Waterman score: 6325; 84.4% identity (84.5% similar) in 1181 aa overlap (40-1037:290-1470)
10 20 30 40 50 60
pF1KA0 CNSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREEREEYSQYAT
.:::::::::::::::::::::::::::::
XP_016 KNGSGVKHHIASDIASDRKTSSELLNSKIISRKRSPSVSRDQNRRYDQREEREEYSQYAT
260 270 280 290 300 310
70 80 90 100 110 120
pF1KA0 SDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYE
320 330 340 350 360 370
130 140 150 160 170 180
pF1KA0 RQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDS
380 390 400 410 420 430
190 200 210 220 230 240
pF1KA0 RISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPL
440 450 460 470 480 490
250 260 270 280 290 300
pF1KA0 PIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKS
500 510 520 530 540 550
310 320 330 340 350 360
pF1KA0 KKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSN
560 570 580 590 600 610
370 380 390 400 410 420
pF1KA0 TRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKD
620 630 640 650 660 670
430 440 450 460 470 480
pF1KA0 GDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGH
680 690 700 710 720 730
490 500 510 520 530 540
pF1KA0 LRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLES
740 750 760 770 780 790
550 560 570 580 590 600
pF1KA0 SSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDL
800 810 820 830 840 850
610 620 630 640 650 660
pF1KA0 PSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLE
860 870 880 890 900 910
670 680 690 700 710 720
pF1KA0 ITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQL
920 930 940 950 960 970
730 740 750 760 770 780
pF1KA0 HGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCS
980 990 1000 1010 1020 1030
790 800 810 820 830 840
pF1KA0 PSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYS
1040 1050 1060 1070 1080 1090
850 860 870 880 890 900
pF1KA0 PDRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPS
1100 1110 1120 1130 1140 1150
910 920 930 940 950
pF1KA0 PALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRK------------------
::::::::::::::::::::::::::::::::::::::::::
XP_016 PALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRKELDSTRRRYAGTMDIEER
1160 1170 1180 1190 1200 1210
pF1KA0 ------------------------------------------------------------
XP_016 NRQMKINKYKQVAGSDPRLEQDYHSKYRSGWDPHRGADNVSTKSSDSDVSDISAVSRTSS
1220 1230 1240 1250 1260 1270
pF1KA0 ------------------------------------------------------------
XP_016 ASRFSSTSYMSVQSERPGGNKKISVFTSKMQSRQMGISGKNMTKSTSISGDMCSLEKNDG
1280 1290 1300 1310 1320 1330
960
pF1KA0 ---------------------------------------------AGGKKLRSTVQRSTE
:::::::::::::::
XP_016 SQSDTAVGTLGTSGKKRRSSLGAKMVAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTE
1340 1350 1360 1370 1380 1390
970 980 990 1000 1010 1020
pF1KA0 TGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVG
1400 1410 1420 1430 1440 1450
1030 1040 1050 1060 1070 1080
pF1KA0 RQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAK
:::::::::::
XP_016 RQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAK
1460 1470 1480 1490 1500 1510
>--
initn: 981 init1: 981 opt: 981 Z-score: 581.8 bits: 120.1 E(85289): 1.1e-25
Smith-Waterman score: 981; 100.0% identity (100.0% similar) in 151 aa overlap (1038-1188:1471-1621)
1010 1020 1030 1040 1050 1060
pF1KA0 SDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKT
::::::::::::::::::::::::::::::
XP_016 SDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKT
1450 1460 1470 1480 1490 1500
1070 1080 1090 1100 1110 1120
pF1KA0 LPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMD
1510 1520 1530 1540 1550 1560
1130 1140 1150 1160 1170 1180
pF1KA0 HKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSR
1570 1580 1590 1600 1610 1620
pF1KA0 S
:
XP_016 S
>>XP_016869495 (OMIM: 606630) PREDICTED: regulating syna (1705 aa)
initn: 6145 init1: 6145 opt: 6163 Z-score: 3582.8 bits: 675.5 E(85289): 7.9e-193
Smith-Waterman score: 6163; 96.9% identity (98.2% similar) in 950 aa overlap (40-989:290-1234)
10 20 30 40 50 60
pF1KA0 CNSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREEREEYSQYAT
.:::::::::::::::::::::::::::::
XP_016 KNGSGVKHHIASDIASDRKTSSELLNSKIISRKRSPSVSRDQNRRYDQREEREEYSQYAT
260 270 280 290 300 310
70 80 90 100 110 120
pF1KA0 SDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYE
320 330 340 350 360 370
130 140 150 160 170 180
pF1KA0 RQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDS
380 390 400 410 420 430
190 200 210 220 230 240
pF1KA0 RISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPL
440 450 460 470 480 490
250 260 270 280 290 300
pF1KA0 PIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKS
500 510 520 530 540 550
310 320 330 340 350 360
pF1KA0 KKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSN
560 570 580 590 600 610
370 380 390 400 410 420
pF1KA0 TRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKD
620 630 640 650 660 670
430 440 450 460 470 480
pF1KA0 GDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGH
680 690 700 710 720 730
490 500 510 520 530 540
pF1KA0 LRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLES
740 750 760 770 780 790
550 560 570 580 590 600
pF1KA0 SSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDL
800 810 820 830 840 850
610 620 630 640 650 660
pF1KA0 PSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLE
860 870 880 890 900 910
670 680 690 700 710 720
pF1KA0 ITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQL
920 930 940 950 960 970
730 740 750 760 770 780
pF1KA0 HGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCS
980 990 1000 1010 1020 1030
790 800 810 820 830 840
pF1KA0 PSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYS
1040 1050 1060 1070 1080 1090
850 860 870 880 890 900
pF1KA0 PDRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPS
1100 1110 1120 1130 1140 1150
910 920 930 940 950 960
pF1KA0 PALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRKAGGKKLRSTVQRSTETGL
:::::::::::::::::::::::::::::::::::::::::: .: :: .: . : .
XP_016 PALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRK----ELDSTRRRYAGT-M
1160 1170 1180 1190 1200 1210
970 980 990 1000 1010 1020
pF1KA0 AVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQT
.: :: . . . ... ::
XP_016 DIEERNRQMKINKYKQVAGSDPRLEQDYHSKYRSGWDPHRGADNVSTKSSDSDVSDISAV
1220 1230 1240 1250 1260 1270
>--
initn: 1580 init1: 1538 opt: 1561 Z-score: 917.4 bits: 182.3 E(85289): 2.3e-44
Smith-Waterman score: 1561; 60.3% identity (74.4% similar) in 473 aa overlap (731-1188:1249-1705)
710 720 730 740 750
pF1KA0 EPHWYKLQTHDVSSLPLPHPSPYMPRRQLHGESPTRRLQR-SKRISDSEVSDYDCDDGIG
: .: : . : . :::.::: :.
XP_016 RNRQMKINKYKQVAGSDPRLEQDYHSKYRSGWDPHRGADNVSTKSSDSDVSD------IS
1220 1230 1240 1250 1260 1270
760 770 780 790 800 810
pF1KA0 VVSDYRHDGRDLQSSTLSVPEQVMSSNH-CSPSG---SPHRVDVIGRTRSWSPSVPPPQS
.:: .: ..: .:: . ..:. :.: . .. : . . : .
XP_016 AVSRTSSASRFSSTSYMSVQSERPGGNKKIRPKGIEEGGKEGDKHEEIVHEKEEVKEERI
1280 1290 1300 1310 1320 1330
820 830 840 850 860 870
pF1KA0 RNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYSPDRDRDCEAADRQPYHRSRSTEQRPL
. :.: . ..: . . : : :.....: : .. .. : ... .: : .. .
XP_016 NENEKGKEIAKTCNKEKNRESG-DEEKTQDIH---EQGKEKEQWNKEDLQRRFSQDDTSV
1340 1350 1360 1370 1380
880 890 900 910 920
pF1KA0 LERTTTRSRSTERPDTNLMRS------MPSLMTGRSAPPSPALSRSHPRTGSVQTSPSST
. . .::. :. .: : :: . .. . :.. . ..: ..
XP_016 FT-SKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAVGTLGTSGKKRRSSLGAK
1390 1400 1410 1420 1430 1440
930 940 950 960 970 980
pF1KA0 PVA----GRRGRQLPQLPPKGTLDRKAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRES
:: .:..:. :: . .::::::::::::::::::::::::::::::::::
XP_016 MVAIVGLSRKSRSASQLS-----QTEAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRES
1450 1460 1470 1480 1490 1500
990 1000 1010 1020 1030 1040
pF1KA0 TDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDK
1510 1520 1530 1540 1550 1560
1050 1060 1070 1080 1090 1100
pF1KA0 KGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLS
1570 1580 1590 1600 1610 1620
1110 1120 1130 1140 1150 1160
pF1KA0 FEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTL
1630 1640 1650 1660 1670 1680
1170 1180
pF1KA0 APLTRRASQSSLESSTGPSYSRS
:::::::::::::::::::::::
XP_016 APLTRRASQSSLESSTGPSYSRS
1690 1700
>>XP_016869502 (OMIM: 606630) PREDICTED: regulating syna (1607 aa)
initn: 6144 init1: 6144 opt: 6162 Z-score: 3582.6 bits: 675.3 E(85289): 8.2e-193
Smith-Waterman score: 6324; 84.5% identity (84.5% similar) in 1180 aa overlap (41-1037:277-1456)
20 30 40 50 60 70
pF1KA0 NSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREEREEYSQYATS
::::::::::::::::::::::::::::::
XP_016 KSRSHGLTRQHSIKNGSGVKHHIASDIASDRKRSPSVSRDQNRRYDQREEREEYSQYATS
250 260 270 280 290 300
80 90 100 110 120 130
pF1KA0 DTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYER
310 320 330 340 350 360
140 150 160 170 180 190
pF1KA0 QRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDSR
370 380 390 400 410 420
200 210 220 230 240 250
pF1KA0 ISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPLP
430 440 450 460 470 480
260 270 280 290 300 310
pF1KA0 IDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKSK
490 500 510 520 530 540
320 330 340 350 360 370
pF1KA0 KGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSNT
550 560 570 580 590 600
380 390 400 410 420 430
pF1KA0 RSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKDG
610 620 630 640 650 660
440 450 460 470 480 490
pF1KA0 DRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHL
670 680 690 700 710 720
500 510 520 530 540 550
pF1KA0 RPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESS
730 740 750 760 770 780
560 570 580 590 600 610
pF1KA0 SSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDLP
790 800 810 820 830 840
620 630 640 650 660 670
pF1KA0 SREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEI
850 860 870 880 890 900
680 690 700 710 720 730
pF1KA0 TLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQLH
910 920 930 940 950 960
740 750 760 770 780 790
pF1KA0 GESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCSP
970 980 990 1000 1010 1020
800 810 820 830 840 850
pF1KA0 SGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYSP
1030 1040 1050 1060 1070 1080
860 870 880 890 900 910
pF1KA0 DRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPSP
1090 1100 1110 1120 1130 1140
920 930 940 950
pF1KA0 ALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRK-------------------
:::::::::::::::::::::::::::::::::::::::::
XP_016 ALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRKELDSTRRRYAGTMDIEERN
1150 1160 1170 1180 1190 1200
pF1KA0 ------------------------------------------------------------
XP_016 RQMKINKYKQVAGSDPRLEQDYHSKYRSGWDPHRGADNVSTKSSDSDVSDISAVSRTSSA
1210 1220 1230 1240 1250 1260
pF1KA0 ------------------------------------------------------------
XP_016 SRFSSTSYMSVQSERPGGNKKISVFTSKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGS
1270 1280 1290 1300 1310 1320
960
pF1KA0 --------------------------------------------AGGKKLRSTVQRSTET
::::::::::::::::
XP_016 QSDTAVGTLGTSGKKRRSSLGAKMVAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTET
1330 1340 1350 1360 1370 1380
970 980 990 1000 1010 1020
pF1KA0 GLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGR
1390 1400 1410 1420 1430 1440
1030 1040 1050 1060 1070 1080
pF1KA0 QTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKK
::::::::::
XP_016 QTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKK
1450 1460 1470 1480 1490 1500
>--
initn: 981 init1: 981 opt: 981 Z-score: 581.9 bits: 120.1 E(85289): 1.1e-25
Smith-Waterman score: 981; 100.0% identity (100.0% similar) in 151 aa overlap (1038-1188:1457-1607)
1010 1020 1030 1040 1050 1060
pF1KA0 SDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKT
::::::::::::::::::::::::::::::
XP_016 SDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKT
1430 1440 1450 1460 1470 1480
1070 1080 1090 1100 1110 1120
pF1KA0 LPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMD
1490 1500 1510 1520 1530 1540
1130 1140 1150 1160 1170 1180
pF1KA0 HKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSR
1550 1560 1570 1580 1590 1600
pF1KA0 S
:
XP_016 S
>>XP_016869501 (OMIM: 606630) PREDICTED: regulating syna (1610 aa)
initn: 7663 init1: 6139 opt: 6139 Z-score: 3569.3 bits: 672.9 E(85289): 4.5e-192
Smith-Waterman score: 6416; 85.3% identity (85.4% similar) in 1181 aa overlap (40-1048:290-1470)
10 20 30 40 50 60
pF1KA0 CNSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREEREEYSQYAT
.:::::::::::::::::::::::::::::
XP_016 KNGSGVKHHIASDIASDRKTSSELLNSKIISRKRSPSVSRDQNRRYDQREEREEYSQYAT
260 270 280 290 300 310
70 80 90 100 110 120
pF1KA0 SDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYE
320 330 340 350 360 370
130 140 150 160 170 180
pF1KA0 RQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDS
380 390 400 410 420 430
190 200 210 220 230 240
pF1KA0 RISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPL
440 450 460 470 480 490
250 260 270 280 290 300
pF1KA0 PIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKS
500 510 520 530 540 550
310 320 330 340 350 360
pF1KA0 KKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSN
560 570 580 590 600 610
370 380 390 400 410 420
pF1KA0 TRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKD
620 630 640 650 660 670
430 440 450 460 470 480
pF1KA0 GDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGH
680 690 700 710 720 730
490 500 510 520 530 540
pF1KA0 LRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLES
740 750 760 770 780 790
550 560 570 580 590 600
pF1KA0 SSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDL
800 810 820 830 840 850
610 620 630 640 650 660
pF1KA0 PSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLE
860 870 880 890 900 910
670 680 690 700 710 720
pF1KA0 ITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQL
920 930 940 950 960 970
730 740 750 760 770 780
pF1KA0 HGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCS
980 990 1000 1010 1020 1030
790 800 810 820 830 840
pF1KA0 PSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYS
1040 1050 1060 1070 1080 1090
850 860 870 880 890 900
pF1KA0 PDRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPS
1100 1110 1120 1130 1140 1150
910 920 930 940 950
pF1KA0 PALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDR-------------------
:::::::::::::::::::::::::::::::::::::::::
XP_016 PALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRSTMDIEERNRQMKINKYKQ
1160 1170 1180 1190 1200 1210
pF1KA0 ------------------------------------------------------------
XP_016 VAGSDPRLEQDYHSKYRSGWDPHRGADNVSTKSSDSDVSDISAVSRTSSASRFSSTSYMS
1220 1230 1240 1250 1260 1270
pF1KA0 ------------------------------------------------------------
XP_016 VQSERPGGNKKISVFTSKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAVGTLG
1280 1290 1300 1310 1320 1330
960 970
pF1KA0 ---------------------------------KAGGKKLRSTVQRSTETGLAVEMRNWM
.::::::::::::::::::::::::::
XP_016 TSGKKRRSSLGAKMVAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTETGLAVEMRNWM
1340 1350 1360 1370 1380 1390
980 990 1000 1010 1020 1030
pF1KA0 TRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGD
1400 1410 1420 1430 1440 1450
1040 1050 1060 1070 1080 1090
pF1KA0 IQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLE
:::::::::::
XP_016 IQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLE
1460 1470 1480 1490 1500 1510
>--
initn: 907 init1: 907 opt: 907 Z-score: 539.0 bits: 112.2 E(85289): 2.8e-23
Smith-Waterman score: 907; 100.0% identity (100.0% similar) in 140 aa overlap (1049-1188:1471-1610)
1020 1030 1040 1050 1060 1070
pF1KA0 LGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLL
::::::::::::::::::::::::::::::
XP_016 LGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLL
1450 1460 1470 1480 1490 1500
1080 1090 1100 1110 1120 1130
pF1KA0 DNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQIL
1510 1520 1530 1540 1550 1560
1140 1150 1160 1170 1180
pF1KA0 LDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
1570 1580 1590 1600 1610
>>XP_005251164 (OMIM: 606630) PREDICTED: regulating syna (1552 aa)
initn: 7662 init1: 6138 opt: 6138 Z-score: 3568.9 bits: 672.8 E(85289): 4.7e-192
Smith-Waterman score: 6415; 85.3% identity (85.4% similar) in 1180 aa overlap (41-1048:233-1412)
20 30 40 50 60 70
pF1KA0 NSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREEREEYSQYATS
::::::::::::::::::::::::::::::
XP_005 KSRSHGLTRQHSIKNGSGVKHHIASDIASDRKRSPSVSRDQNRRYDQREEREEYSQYATS
210 220 230 240 250 260
80 90 100 110 120 130
pF1KA0 DTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYER
270 280 290 300 310 320
140 150 160 170 180 190
pF1KA0 QRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDSR
330 340 350 360 370 380
200 210 220 230 240 250
pF1KA0 ISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPLP
390 400 410 420 430 440
260 270 280 290 300 310
pF1KA0 IDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKSK
450 460 470 480 490 500
320 330 340 350 360 370
pF1KA0 KGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSNT
510 520 530 540 550 560
380 390 400 410 420 430
pF1KA0 RSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKDG
570 580 590 600 610 620
440 450 460 470 480 490
pF1KA0 DRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHL
630 640 650 660 670 680
500 510 520 530 540 550
pF1KA0 RPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESS
690 700 710 720 730 740
560 570 580 590 600 610
pF1KA0 SSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDLP
750 760 770 780 790 800
620 630 640 650 660 670
pF1KA0 SREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEI
810 820 830 840 850 860
680 690 700 710 720 730
pF1KA0 TLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQLH
870 880 890 900 910 920
740 750 760 770 780 790
pF1KA0 GESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCSP
930 940 950 960 970 980
800 810 820 830 840 850
pF1KA0 SGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYSP
990 1000 1010 1020 1030 1040
860 870 880 890 900 910
pF1KA0 DRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRDRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPSP
1050 1060 1070 1080 1090 1100
920 930 940 950
pF1KA0 ALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDR--------------------
::::::::::::::::::::::::::::::::::::::::
XP_005 ALSRSHPRTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRSTMDIEERNRQMKINKYKQV
1110 1120 1130 1140 1150 1160
pF1KA0 ------------------------------------------------------------
XP_005 AGSDPRLEQDYHSKYRSGWDPHRGADNVSTKSSDSDVSDISAVSRTSSASRFSSTSYMSV
1170 1180 1190 1200 1210 1220
pF1KA0 ------------------------------------------------------------
XP_005 QSERPGGNKKISVFTSKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAVGTLGT
1230 1240 1250 1260 1270 1280
960 970
pF1KA0 --------------------------------KAGGKKLRSTVQRSTETGLAVEMRNWMT
.:::::::::::::::::::::::::::
XP_005 SGKKRRSSLGAKMVAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTETGLAVEMRNWMT
1290 1300 1310 1320 1330 1340
980 990 1000 1010 1020 1030
pF1KA0 RQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDI
1350 1360 1370 1380 1390 1400
1040 1050 1060 1070 1080 1090
pF1KA0 QVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEP
::::::::::
XP_005 QVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEP
1410 1420 1430 1440 1450 1460
>--
initn: 907 init1: 907 opt: 907 Z-score: 539.2 bits: 112.2 E(85289): 2.7e-23
Smith-Waterman score: 907; 100.0% identity (100.0% similar) in 140 aa overlap (1049-1188:1413-1552)
1020 1030 1040 1050 1060 1070
pF1KA0 LGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLL
::::::::::::::::::::::::::::::
XP_005 LGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLL
1390 1400 1410 1420 1430 1440
1080 1090 1100 1110 1120 1130
pF1KA0 DNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQIL
1450 1460 1470 1480 1490 1500
1140 1150 1160 1170 1180
pF1KA0 LDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
1510 1520 1530 1540 1550
>>XP_016869532 (OMIM: 606630) PREDICTED: regulating syna (1210 aa)
initn: 5761 init1: 5761 opt: 5799 Z-score: 3374.1 bits: 636.3 E(85289): 3.4e-181
Smith-Waterman score: 7897; 98.2% identity (98.2% similar) in 1210 aa overlap (1-1188:1-1210)
10 20 30 40 50 60
pF1KA0 MQFETLRQVCNSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFETLRQVCNSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 REEYSQYATSDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEYSQYATSDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DVESRDEYERQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVESRDEYERQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LANADLEDSRISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANADLEDSRISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 PPTPRRSPLPIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPTPRRSPLPIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PPPPKPHKSKKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPKPHKSKKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 EQAVLSDSNTRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAVLSDSNTRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 PVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 GSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 DSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 VTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 REFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 SPYMPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPYMPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QVMSSNHCSPSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVMSSNHCSPSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDR
790 800 810 820 830 840
850 860 870
pF1KA0 HRVMDDHYSPDRD----------------------RDCEAADRQPYHRSRSTEQRPLLER
::::::::::::: :::::::::::::::::::::::::
XP_016 HRVMDDHYSPDRDSHFLTLPRSRYSQTIDHHHRDGRDCEAADRQPYHRSRSTEQRPLLER
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 TTTRSRSTERPDTNLMRSMPSLMTGRSAPPSPALSRSHPRTGSVQTSPSSTPVAGRRGRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTTRSRSTERPDTNLMRSMPSLMTGRSAPPSPALSRSHPRTGSVQTSPSSTPVAGRRGRQ
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 LPQLPPKGTLDRKAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQLPPKGTLDRKAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGN
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 LIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARG
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KA0 LVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQII
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KA0 VWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLE
1150 1160 1170 1180 1190 1200
1180
pF1KA0 SSTGPSYSRS
::::::::::
XP_016 SSTGPSYSRS
1210
>>XP_016869511 (OMIM: 606630) PREDICTED: regulating syna (1477 aa)
initn: 7285 init1: 5761 opt: 5797 Z-score: 3371.7 bits: 636.2 E(85289): 4.6e-181
Smith-Waterman score: 6378; 95.1% identity (96.1% similar) in 1011 aa overlap (1-989:1-1006)
10 20 30 40 50 60
pF1KA0 MQFETLRQVCNSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFETLRQVCNSVLSHFHGVFSSPPNILQNELFGQTLNNARKRSPSVSRDQNRRYDQREE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 REEYSQYATSDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEYSQYATSDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DVESRDEYERQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVESRDEYERQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LANADLEDSRISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANADLEDSRISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 PPTPRRSPLPIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPTPRRSPLPIDRPDLRRTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PPPPKPHKSKKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPKPHKSKKGGKMRQISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 EQAVLSDSNTRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAVLSDSNTRSERQKEMMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 PVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 GSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 DSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 VTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 REFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 SPYMPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPYMPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QVMSSNHCSPSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVMSSNHCSPSGSPHRVDVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDR
790 800 810 820 830 840
850 860 870
pF1KA0 HRVMDDHYSPDRD----------------------RDCEAADRQPYHRSRSTEQRPLLER
::::::::::::: :::::::::::::::::::::::::
XP_016 HRVMDDHYSPDRDSHFLTLPRSRYSQTIDHHHRDGRDCEAADRQPYHRSRSTEQRPLLER
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 TTTRSRSTERPDTNLMRSMPSLMTGRSAPPSPALSRSHPRTGSVQTSPSSTPVAGRRGRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTTRSRSTERPDTNLMRSMPSLMTGRSAPPSPALSRSHPRTGSVQTSPSSTPVAGRRGRQ
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 LPQLPPKGTLDRKAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGN
:::::::::::: :.: :: .: . : . .: :: . . . ... ::
XP_016 LPQLPPKGTLDR----KELDSTRRRYAGT-MDIEERNRQMKINKYKQVAGSDPRLEQDYH
970 980 990 1000 1010
1000 1010 1020 1030 1040 1050
pF1KA0 LIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARG
XP_016 SKYRSGWDPHRGADNVSTKSSDSDVSDISAVSRTSSASRFSSTSYMSVQSERPGGNKKIR
1020 1030 1040 1050 1060 1070
>--
initn: 1580 init1: 1538 opt: 1561 Z-score: 918.3 bits: 182.2 E(85289): 2.1e-44
Smith-Waterman score: 1561; 60.3% identity (74.4% similar) in 473 aa overlap (731-1188:1021-1477)
710 720 730 740 750
pF1KA0 EPHWYKLQTHDVSSLPLPHPSPYMPRRQLHGESPTRRLQR-SKRISDSEVSDYDCDDGIG
: .: : . : . :::.::: :.
XP_016 RNRQMKINKYKQVAGSDPRLEQDYHSKYRSGWDPHRGADNVSTKSSDSDVSD------IS
1000 1010 1020 1030 1040
760 770 780 790 800 810
pF1KA0 VVSDYRHDGRDLQSSTLSVPEQVMSSNH-CSPSG---SPHRVDVIGRTRSWSPSVPPPQS
.:: .: ..: .:: . ..:. :.: . .. : . . : .
XP_016 AVSRTSSASRFSSTSYMSVQSERPGGNKKIRPKGIEEGGKEGDKHEEIVHEKEEVKEERI
1050 1060 1070 1080 1090 1100
820 830 840 850 860 870
pF1KA0 RNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYSPDRDRDCEAADRQPYHRSRSTEQRPL
. :.: . ..: . . : : :.....: : .. .. : ... .: : .. .
XP_016 NENEKGKEIAKTCNKEKNRESG-DEEKTQDIH---EQGKEKEQWNKEDLQRRFSQDDTSV
1110 1120 1130 1140 1150 1160
880 890 900 910 920
pF1KA0 LERTTTRSRSTERPDTNLMRS------MPSLMTGRSAPPSPALSRSHPRTGSVQTSPSST
. . .::. :. .: : :: . .. . :.. . ..: ..
XP_016 FT-SKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAVGTLGTSGKKRRSSLGAK
1170 1180 1190 1200 1210
930 940 950 960 970 980
pF1KA0 PVA----GRRGRQLPQLPPKGTLDRKAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRES
:: .:..:. :: . .::::::::::::::::::::::::::::::::::
XP_016 MVAIVGLSRKSRSASQLS-----QTEAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRES
1220 1230 1240 1250 1260 1270
990 1000 1010 1020 1030 1040
pF1KA0 TDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDK
1280 1290 1300 1310 1320 1330
1050 1060 1070 1080 1090 1100
pF1KA0 KGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLS
1340 1350 1360 1370 1380 1390
1110 1120 1130 1140 1150 1160
pF1KA0 FEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTL
1400 1410 1420 1430 1440 1450
1170 1180
pF1KA0 APLTRRASQSSLESSTGPSYSRS
:::::::::::::::::::::::
XP_016 APLTRRASQSSLESSTGPSYSRS
1460 1470
1188 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:15:56 2016 done: Thu Nov 3 10:15:58 2016
Total Scan time: 18.010 Total Display time: 0.430
Function used was FASTA [36.3.4 Apr, 2011]