FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0773, 360 aa 1>>>pF1KA0773 360 - 360 aa - 360 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4952+/-0.000833; mu= 7.4060+/- 0.050 mean_var=128.5632+/-25.926, 0's: 0 Z-trim(111.4): 11 B-trim: 0 in 0/50 Lambda= 0.113114 statistics sampled from 12361 (12366) to 12361 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.38), width: 16 Scan time: 2.850 The best scores are: opt bits E(32554) CCDS47734.1 FAM131B gene_id:9715|Hs108|chr7 ( 360) 2440 409.0 3.2e-114 CCDS5882.1 FAM131B gene_id:9715|Hs108|chr7 ( 332) 2248 377.6 8.1e-105 CCDS3262.2 FAM131A gene_id:131408|Hs108|chr3 ( 366) 506 93.4 3.3e-19 CCDS54689.1 FAM131A gene_id:131408|Hs108|chr3 ( 281) 451 84.3 1.3e-16 CCDS41270.1 FAM131C gene_id:348487|Hs108|chr1 ( 280) 394 75.0 8.4e-14 >>CCDS47734.1 FAM131B gene_id:9715|Hs108|chr7 (360 aa) initn: 2440 init1: 2440 opt: 2440 Z-score: 2164.1 bits: 409.0 E(32554): 3.2e-114 Smith-Waterman score: 2440; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360) 10 20 30 40 50 60 pF1KA0 MGCIGSRTVGNEVIAVDWKGLKDVDQINMDSTSSLHGSSLHRPSTEQTRTDFSWDGINLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MGCIGSRTVGNEVIAVDWKGLKDVDQINMDSTSSLHGSSLHRPSTEQTRTDFSWDGINLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 MEDTTSILPKLKRNSNAYGIGALAKSSFSGISRSMKDHVTKPTAMGQGRVAHMIEWQGWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MEDTTSILPKLKRNSNAYGIGALAKSSFSGISRSMKDHVTKPTAMGQGRVAHMIEWQGWG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KTPAVQPQHSHESVRRDTDAYSDLSDGEKEARFLAGVMEQFAISEATLMAWSSMDGEDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KTPAVQPQHSHESVRRDTDAYSDLSDGEKEARFLAGVMEQFAISEATLMAWSSMDGEDMS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VNSTQEPLGCNYSDNYQELMDSQDALAQAPMDGWPHSYVSQGMYCLGSSDAWEASDQSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VNSTQEPLGCNYSDNYQELMDSQDALAQAPMDGWPHSYVSQGMYCLGSSDAWEASDQSLI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ASPATGSYLGPAFDDSQPSLHEMGPSQPASGYSALEPPPLLGGDTDWAPGVGAVDLARGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ASPATGSYLGPAFDDSQPSLHEMGPSQPASGYSALEPPPLLGGDTDWAPGVGAVDLARGP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 AEEEKRPLAPEEEEDAGCRDLESLSPREDPEMSTALSRKVSDVTSSGVQSFDEEEGEANN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 AEEEKRPLAPEEEEDAGCRDLESLSPREDPEMSTALSRKVSDVTSSGVQSFDEEEGEANN 310 320 330 340 350 360 >>CCDS5882.1 FAM131B gene_id:9715|Hs108|chr7 (332 aa) initn: 2248 init1: 2248 opt: 2248 Z-score: 1995.3 bits: 377.6 E(32554): 8.1e-105 Smith-Waterman score: 2248; 100.0% identity (100.0% similar) in 332 aa overlap (29-360:1-332) 10 20 30 40 50 60 pF1KA0 MGCIGSRTVGNEVIAVDWKGLKDVDQINMDSTSSLHGSSLHRPSTEQTRTDFSWDGINLS :::::::::::::::::::::::::::::::: CCDS58 MDSTSSLHGSSLHRPSTEQTRTDFSWDGINLS 10 20 30 70 80 90 100 110 120 pF1KA0 MEDTTSILPKLKRNSNAYGIGALAKSSFSGISRSMKDHVTKPTAMGQGRVAHMIEWQGWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MEDTTSILPKLKRNSNAYGIGALAKSSFSGISRSMKDHVTKPTAMGQGRVAHMIEWQGWG 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA0 KTPAVQPQHSHESVRRDTDAYSDLSDGEKEARFLAGVMEQFAISEATLMAWSSMDGEDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KTPAVQPQHSHESVRRDTDAYSDLSDGEKEARFLAGVMEQFAISEATLMAWSSMDGEDMS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA0 VNSTQEPLGCNYSDNYQELMDSQDALAQAPMDGWPHSYVSQGMYCLGSSDAWEASDQSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VNSTQEPLGCNYSDNYQELMDSQDALAQAPMDGWPHSYVSQGMYCLGSSDAWEASDQSLI 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA0 ASPATGSYLGPAFDDSQPSLHEMGPSQPASGYSALEPPPLLGGDTDWAPGVGAVDLARGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ASPATGSYLGPAFDDSQPSLHEMGPSQPASGYSALEPPPLLGGDTDWAPGVGAVDLARGP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA0 AEEEKRPLAPEEEEDAGCRDLESLSPREDPEMSTALSRKVSDVTSSGVQSFDEEEGEANN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AEEEKRPLAPEEEEDAGCRDLESLSPREDPEMSTALSRKVSDVTSSGVQSFDEEEGEANN 280 290 300 310 320 330 >>CCDS3262.2 FAM131A gene_id:131408|Hs108|chr3 (366 aa) initn: 539 init1: 255 opt: 506 Z-score: 458.3 bits: 93.4 E(32554): 3.3e-19 Smith-Waterman score: 583; 38.3% identity (61.7% similar) in 368 aa overlap (3-357:24-362) 10 20 30 pF1KA0 MGCIGSRTVGNE-VIAVDWKGL-KDVDQINMDSTSSLHG : :: :... . ::.: : . .. .. :. .:.: CCDS32 MPMISVLGKMFLWQREGPGGRWTCQTSRRVSSDPAWAVEWIELPRGLSLSSLGSARTLRG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 -SSLHRPSTEQTRTDFSWDGINLSMEDTTSILPKLKRNSNAYGIGALAKSSFSGISRSMK : :::. .: : : .... ::...::: .: . :.:::.::. :::. .: CCDS32 WSRSSRPSS----VD-SQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVK 70 80 90 100 110 100 110 120 130 140 150 pF1KA0 DHVTKPTAMGQGRVAHMIEWQGWGKTPAVQPQHSHESVRRDTDAYSDLSDGEKEARFLAG :::::::::.::::::.:::.::.: :. : ... ..:::::.::.:::: :: CCDS32 DHVTKPTAMAQGRVAHLIEWKGWSK-----PSDSPAALESAFSSYSDLSEGEQEARFAAG 120 130 140 150 160 170 160 170 180 190 200 210 pF1KA0 VMEQFAISEATLMAWSSMDGEDMSVNSTQEPLGCNYSDNYQELMDSQDALAQAPMDGWP- : :::::.:: : ::::.:::: . .: .: ... ... : .: :. .: . CCDS32 VAEQFAIAEAKLRAWSSVDGEDSTDDSYDE----DFAGGMDTDMAGQLPLGPHLQDLFTG 180 190 200 210 220 220 230 240 250 260 pF1KA0 HSY---VSQGMYCLGSSDAWEASDQSLIASPAT--GSYLG-PAFDDSQPSLHEMGPSQ-P : . : :: :. . .: ..: .: . . :: :: :: :. .. : CCDS32 HRFSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARLASQLLGDELLLAKLP 230 240 250 260 270 280 270 280 290 300 310 320 pF1KA0 ASGYSALEP-PPLLGGDTDWAPGVGAVDLARGPAEEEKRPLAPEEEEDAGCRDLESLSPR : ::.. :: . :. : .: : :.: ::: : :.: . : : CCDS32 PSRESAFRSLGPLEAQDS----------LYNSPLTESC--LSPAEEEPAPCKDCQPLCP- 290 300 310 320 330 330 340 350 360 pF1KA0 EDPEMST-ALSRKVSDVTSSGVQSFDEEEGEANN : .. .:..::..:::: :.::.:.: CCDS32 --PLTGSWERQRQASDLASSGVVSLDEDEAEPEEQ 340 350 360 >>CCDS54689.1 FAM131A gene_id:131408|Hs108|chr3 (281 aa) initn: 551 init1: 241 opt: 451 Z-score: 411.5 bits: 84.3 E(32554): 1.3e-16 Smith-Waterman score: 528; 40.2% identity (61.8% similar) in 301 aa overlap (67-357:1-277) 40 50 60 70 80 90 pF1KA0 GSSLHRPSTEQTRTDFSWDGINLSMEDTTSILPKLKRNSNAYGIGALAKSSFSGISRSMK .::: .: . :.:::.::. :::. .: CCDS54 MLPKSRRALTIQEIAALARSSLHGISQVVK 10 20 30 100 110 120 130 140 150 pF1KA0 DHVTKPTAMGQGRVAHMIEWQGWGKTPAVQPQHSHESVRRDTDAYSDLSDGEKEARFLAG :::::::::.::::::.:::.::.: :. : ... ..:::::.::.:::: :: CCDS54 DHVTKPTAMAQGRVAHLIEWKGWSK-----PSDSPAALESAFSSYSDLSEGEQEARFAAG 40 50 60 70 80 160 170 180 190 200 210 pF1KA0 VMEQFAISEATLMAWSSMDGEDMSVNSTQEPLGCNYSDNYQELMDSQDALAQAPMDGWP- : :::::.:: : ::::.:::: . .: .: ... ... : .: :. .: . CCDS54 VAEQFAIAEAKLRAWSSVDGEDSTDDSYDE----DFAGGMDTDMAGQLPLGPHLQDLFTG 90 100 110 120 130 140 220 230 240 250 260 pF1KA0 HSY---VSQGMYCLGSSDAWEASDQSLIASPAT--GSYLG-PAFDDSQPSLHEMGPSQ-P : . : :: :. . .: ..: .: . . :: :: :: :. .. : CCDS54 HRFSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARLASQLLGDELLLAKLP 150 160 170 180 190 200 270 280 290 300 310 320 pF1KA0 ASGYSALEP-PPLLGGDTDWAPGVGAVDLARGPAEEEKRPLAPEEEEDAGCRDLESLSPR : ::.. :: . :. : .: : :.: ::: : :.: . : : CCDS54 PSRESAFRSLGPLEAQDS----------LYNSPLTESC--LSPAEEEPAPCKDCQPLCP- 210 220 230 240 330 340 350 360 pF1KA0 EDPEMST-ALSRKVSDVTSSGVQSFDEEEGEANN : .. .:..::..:::: :.::.:.: CCDS54 --PLTGSWERQRQASDLASSGVVSLDEDEAEPEEQ 250 260 270 280 >>CCDS41270.1 FAM131C gene_id:348487|Hs108|chr1 (280 aa) initn: 417 init1: 255 opt: 394 Z-score: 361.3 bits: 75.0 E(32554): 8.4e-14 Smith-Waterman score: 399; 33.8% identity (57.9% similar) in 240 aa overlap (51-287:51-272) 30 40 50 60 70 80 pF1KA0 LKDVDQINMDSTSSLHGSSLHRPSTEQTRTDFSWDGINLSMEDTTSILPKLKRNSNAYGI :: :: . .. :.. : . . :.. CCDS41 QGADPLNPDLPSGRTPTVAPDCVIGKDKQMDFCWDPWQRCFQTTNGYLSDSRSRPGNYNV 30 40 50 60 70 80 90 100 110 120 130 140 pF1KA0 GALAKSSFSGISRSMKDHVTKPTAMGQGRVAHMIEWQGWGKTPAVQPQHSHESVRRDTDA .::: ::. :. .:.:::.::::::..:::::.:::.::. :: . : . . CCDS41 AALATSSLVGVVQSIKDHITKPTAMARGRVAHLIEWKGWSAQPA-----GWELSPAEDEH 90 100 110 120 130 150 160 170 180 190 200 pF1KA0 YSDLSDGEKEARFLAGVMEQFAISEATLMAWSSMDGEDMSVNSTQEPLGCNYSDNYQELM : : : .:::: ::: :::::.:::: ::::.: :.. ... : : .. . .. CCDS41 YCCLPDELREARFAAGVAEQFAITEATLSAWSSLDEEELHPENS--PQGIVQLQDLESIY 140 150 160 170 180 190 210 220 230 240 250 260 pF1KA0 DSQDALAQAPMDGWPHSYVSQGMYCLGSSDAWEASDQSLIASPATGSYLGPAFDDSQPSL ::.: ..: . .... ..: . : : :.:.. : . : CCDS41 -LQDSLPSGPSQ-------DDSLQAFSSPSPSPDSCPSPEEPPSTAGIPQPPSPELQHRR 200 210 220 230 240 270 280 290 300 310 pF1KA0 HEMGPSQPASGYSALEPP---PLLGGDTDWAPGVGAVDLARGPAEEEKRPLAPEEEEDAG . : . : .: .:: : . . . : CCDS41 RLPGAQGPEGG---THPPGSLPSMDSGSLWEEDEVFYN 250 260 270 280 360 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:42:33 2016 done: Wed Nov 2 19:42:33 2016 Total Scan time: 2.850 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]