FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0791, 1332 aa 1>>>pF1KA0791 1332 - 1332 aa - 1332 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3401+/-0.000469; mu= 8.9444+/- 0.029 mean_var=158.1275+/-33.047, 0's: 0 Z-trim(114.6): 4 B-trim: 1186 in 1/50 Lambda= 0.101993 statistics sampled from 24482 (24486) to 24482 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.287), width: 16 Scan time: 17.760 The best scores are: opt bits E(85289) NP_004289 (OMIM: 606694,615770) nuclear pore compl (1332) 8831 1312.7 0 NP_705618 (OMIM: 606694,615770) nuclear pore compl (1391) 8831 1312.7 0 XP_011512467 (OMIM: 606694,615770) PREDICTED: nucl ( 892) 5469 817.9 0 NP_001265241 (OMIM: 606694,615770) nuclear pore co (1327) 5061 757.9 1e-217 >>NP_004289 (OMIM: 606694,615770) nuclear pore complex p (1332 aa) initn: 8831 init1: 8831 opt: 8831 Z-score: 7027.6 bits: 1312.7 E(85289): 0 Smith-Waterman score: 8831; 100.0% identity (100.0% similar) in 1332 aa overlap (1-1332:1-1332) 10 20 30 40 50 60 pF1KA0 MSDMDYPLQGPGLLSVPNLPEISSIRRVPLPPELVEQFGHMQCNCMMGVFPPISRAWLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSDMDYPLQGPGLLSVPNLPEISSIRRVPLPPELVEQFGHMQCNCMMGVFPPISRAWLTI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 DSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YANLQTGSGVLNDSLSGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDGCLYEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YANLQTGSGVLNDSLSGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDGCLYEVA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSEDDPILQIAIDNSRNILYTRSEKGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSEDDPILQIAIDNSRNILYTRSEKGV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 IQVYDLGQDGQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IQVYDLGQDGQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 AVTHAGVRLYFSTCPFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHRALYSKGILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AVTHAGVRLYFSTCPFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHRALYSKGILL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 MAASENEDNDILWCVNHDTFPFQKPMMETQMTAGVDGHSWALSAIDELKVDKIITPLNKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MAASENEDNDILWCVNHDTFPFQKPMMETQMTAGVDGHSWALSAIDELKVDKIITPLNKD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 HIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 KLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPTTLPPPSNVGPILG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPTTLPPPSNVGPILG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SPVYSSSPVPSGSPYPNPSFLGTPSHGIQPPAMSTPVCALGNPATQATNMSCVTGPEIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SPVYSSSPVPSGSPYPNPSFLGTPSHGIQPPAMSTPVCALGNPATQATNMSCVTGPEIVY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 SGKHNGICIYFSRIMGNIWDASLVVERIFKSGNREITAIESSVPCQLLESVLQELKGLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SGKHNGICIYFSRIMGNIWDASLVVERIFKSGNREITAIESSVPCQLLESVLQELKGLQE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 FLDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEKISLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FLDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEKISLQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 AIQQLVRKSYQALALWKLLCEHQFTIIVAELQKELQEQLKITTFKDLVIRDKELTGALIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AIQQLVRKSYQALALWKLLCEHQFTIIVAELQKELQEQLKITTFKDLVIRDKELTGALIA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SLKEYQKISNQVDLSNVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SLKEYQKISNQVDLSNVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 VGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHH 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 FEQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FEQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 LLWRYYEKNRSFSNAARVLSRLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LLWRYYEKNRSFSNAARVLSRLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKLA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 ECKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ECKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTP 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 RFFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRMKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RFFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRMKK 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 PLHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PLHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGN 1270 1280 1290 1300 1310 1320 1330 pF1KA0 FKSLQAKLERLH :::::::::::: NP_004 FKSLQAKLERLH 1330 >>NP_705618 (OMIM: 606694,615770) nuclear pore complex p (1391 aa) initn: 8831 init1: 8831 opt: 8831 Z-score: 7027.3 bits: 1312.7 E(85289): 0 Smith-Waterman score: 8831; 100.0% identity (100.0% similar) in 1332 aa overlap (1-1332:60-1391) 10 20 30 pF1KA0 MSDMDYPLQGPGLLSVPNLPEISSIRRVPL :::::::::::::::::::::::::::::: NP_705 IDRQLQEDRMYPDLSELLMVSAPNNPTVSGMSDMDYPLQGPGLLSVPNLPEISSIRRVPL 30 40 50 60 70 80 40 50 60 70 80 90 pF1KA0 PPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 PPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGL 90 100 110 120 130 140 100 110 120 130 140 150 pF1KA0 VKPKAGIFQPHVRHLLVLATPVDIVILGLSYANLQTGSGVLNDSLSGGMQLLPDPLYSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 VKPKAGIFQPHVRHLLVLATPVDIVILGLSYANLQTGSGVLNDSLSGGMQLLPDPLYSLP 150 160 170 180 190 200 160 170 180 190 200 210 pF1KA0 TDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 TDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLL 210 220 230 240 250 260 220 230 240 250 260 270 pF1KA0 QFTFSEDDPILQIAIDNSRNILYTRSEKGVIQVYDLGQDGQGMSRVASVSQNAIVSAAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 QFTFSEDDPILQIAIDNSRNILYTRSEKGVIQVYDLGQDGQGMSRVASVSQNAIVSAAGN 270 280 290 300 310 320 280 290 300 310 320 330 pF1KA0 IARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 IARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVH 330 340 350 360 370 380 340 350 360 370 380 390 pF1KA0 VRLPPGFSASSTVEKPSKVHRALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 VRLPPGFSASSTVEKPSKVHRALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQ 390 400 410 420 430 440 400 410 420 430 440 450 pF1KA0 MTAGVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 MTAGVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSL 450 460 470 480 490 500 460 470 480 490 500 510 pF1KA0 MFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 MFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWA 510 520 530 540 550 560 520 530 540 550 560 570 pF1KA0 TRAFFRYGGEAQMRFPTTLPPPSNVGPILGSPVYSSSPVPSGSPYPNPSFLGTPSHGIQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 TRAFFRYGGEAQMRFPTTLPPPSNVGPILGSPVYSSSPVPSGSPYPNPSFLGTPSHGIQP 570 580 590 600 610 620 580 590 600 610 620 630 pF1KA0 PAMSTPVCALGNPATQATNMSCVTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERIFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 PAMSTPVCALGNPATQATNMSCVTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERIFK 630 640 650 660 670 680 640 650 660 670 680 690 pF1KA0 SGNREITAIESSVPCQLLESVLQELKGLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 SGNREITAIESSVPCQLLESVLQELKGLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFM 690 700 710 720 730 740 700 710 720 730 740 750 pF1KA0 RPENGNPQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTIIVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 RPENGNPQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTIIVAE 750 760 770 780 790 800 760 770 780 790 800 810 pF1KA0 LQKELQEQLKITTFKDLVIRDKELTGALIASLINCYIRDNAAVDGISLHLQDICPLLYST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 LQKELQEQLKITTFKDLVIRDKELTGALIASLINCYIRDNAAVDGISLHLQDICPLLYST 810 820 830 840 850 860 820 830 840 850 860 870 pF1KA0 DDAICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 DDAICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEGV 870 880 890 900 910 920 880 890 900 910 920 930 pF1KA0 VELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 VELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAA 930 940 950 960 970 980 940 950 960 970 980 990 pF1KA0 PQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLSQRSKDELFSIALYNWLIQVDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 PQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLSQRSKDELFSIALYNWLIQVDLA 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 pF1KA0 DKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 DKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTEI 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 1110 pF1KA0 SLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 SLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHS 1110 1120 1130 1140 1150 1160 1120 1130 1140 1150 1160 1170 pF1KA0 SVQDAVSQLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVQTLWQDIIEKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 SVQDAVSQLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVQTLWQDIIEKEL 1170 1180 1190 1200 1210 1220 1180 1190 1200 1210 1220 1230 pF1KA0 SDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 SDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTM 1230 1240 1250 1260 1270 1280 1240 1250 1260 1270 1280 1290 pF1KA0 NEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 NEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRF 1290 1300 1310 1320 1330 1340 1300 1310 1320 1330 pF1KA0 TNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH :::::::::::::::::::::::::::::::::::::::::: NP_705 TNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH 1350 1360 1370 1380 1390 >>XP_011512467 (OMIM: 606694,615770) PREDICTED: nuclear (892 aa) initn: 5544 init1: 5469 opt: 5469 Z-score: 4356.7 bits: 817.9 E(85289): 0 Smith-Waterman score: 5469; 99.5% identity (100.0% similar) in 821 aa overlap (1-821:60-880) 10 20 30 pF1KA0 MSDMDYPLQGPGLLSVPNLPEISSIRRVPL :::::::::::::::::::::::::::::: XP_011 IDRQLQEDRMYPDLSELLMVSAPNNPTVSGMSDMDYPLQGPGLLSVPNLPEISSIRRVPL 30 40 50 60 70 80 40 50 60 70 80 90 pF1KA0 PPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGL 90 100 110 120 130 140 100 110 120 130 140 150 pF1KA0 VKPKAGIFQPHVRHLLVLATPVDIVILGLSYANLQTGSGVLNDSLSGGMQLLPDPLYSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKPKAGIFQPHVRHLLVLATPVDIVILGLSYANLQTGSGVLNDSLSGGMQLLPDPLYSLP 150 160 170 180 190 200 160 170 180 190 200 210 pF1KA0 TDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLL 210 220 230 240 250 260 220 230 240 250 260 270 pF1KA0 QFTFSEDDPILQIAIDNSRNILYTRSEKGVIQVYDLGQDGQGMSRVASVSQNAIVSAAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFTFSEDDPILQIAIDNSRNILYTRSEKGVIQVYDLGQDGQGMSRVASVSQNAIVSAAGN 270 280 290 300 310 320 280 290 300 310 320 330 pF1KA0 IARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVH 330 340 350 360 370 380 340 350 360 370 380 390 pF1KA0 VRLPPGFSASSTVEKPSKVHRALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRLPPGFSASSTVEKPSKVHRALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQ 390 400 410 420 430 440 400 410 420 430 440 450 pF1KA0 MTAGVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTAGVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSL 450 460 470 480 490 500 460 470 480 490 500 510 pF1KA0 MFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWA 510 520 530 540 550 560 520 530 540 550 560 570 pF1KA0 TRAFFRYGGEAQMRFPTTLPPPSNVGPILGSPVYSSSPVPSGSPYPNPSFLGTPSHGIQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRAFFRYGGEAQMRFPTTLPPPSNVGPILGSPVYSSSPVPSGSPYPNPSFLGTPSHGIQP 570 580 590 600 610 620 580 590 600 610 620 630 pF1KA0 PAMSTPVCALGNPATQATNMSCVTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERIFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAMSTPVCALGNPATQATNMSCVTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERIFK 630 640 650 660 670 680 640 650 660 670 680 690 pF1KA0 SGNREITAIESSVPCQLLESVLQELKGLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGNREITAIESSVPCQLLESVLQELKGLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFM 690 700 710 720 730 740 700 710 720 730 740 750 pF1KA0 RPENGNPQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTIIVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPENGNPQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTIIVAE 750 760 770 780 790 800 760 770 780 790 800 810 pF1KA0 LQKELQEQLKITTFKDLVIRDKELTGALIASLINCYIRDNAAVDGISLHLQDICPLLYST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQKELQEQLKITTFKDLVIRDKELTGALIASLINCYIRDNAAVDGISLHLQDICPLLYST 810 820 830 840 850 860 820 830 840 850 860 870 pF1KA0 DDAICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEGV :::::::.... XP_011 DDAICSKVEKINKSVSHGLPAAQ 870 880 890 >>NP_001265241 (OMIM: 606694,615770) nuclear pore comple (1327 aa) initn: 5055 init1: 5055 opt: 5061 Z-score: 4029.6 bits: 757.9 E(85289): 1e-217 Smith-Waterman score: 8282; 95.2% identity (95.2% similar) in 1332 aa overlap (1-1332:60-1327) 10 20 30 pF1KA0 MSDMDYPLQGPGLLSVPNLPEISSIRRVPL :::::::::::::::::::::::::::::: NP_001 IDRQLQEDRMYPDLSELLMVSAPNNPTVSGMSDMDYPLQGPGLLSVPNLPEISSIRRVPL 30 40 50 60 70 80 40 50 60 70 80 90 pF1KA0 PPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGL 90 100 110 120 130 140 100 110 120 130 140 150 pF1KA0 VKPKAGIFQPHVRHLLVLATPVDIVILGLSYANLQTGSGVLNDSLSGGMQLLPDPLYSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKPKAGIFQPHVRHLLVLATPVDIVILGLSYANLQTGSGVLNDSLSGGMQLLPDPLYSLP 150 160 170 180 190 200 160 170 180 190 200 210 pF1KA0 TDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLL 210 220 230 240 250 260 220 230 240 250 260 270 pF1KA0 QFTFSEDDPILQIAIDNSRNILYTRSEKGVIQVYDLGQDGQGMSRVASVSQNAIVSAAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFTFSEDDPILQIAIDNSRNILYTRSEKGVIQVYDLGQDGQGMSRVASVSQNAIVSAAGN 270 280 290 300 310 320 280 290 300 310 320 330 pF1KA0 IARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVH 330 340 350 360 370 380 340 350 360 370 380 390 pF1KA0 VRLPPGFSASSTVEKPSKVHRALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRLPPGFSASSTVEKPSKVHRALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQ 390 400 410 420 430 440 400 410 420 430 440 450 pF1KA0 MTAGVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTAGVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSL 450 460 470 480 490 500 460 470 480 490 500 510 pF1KA0 MFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWA 510 520 530 540 550 560 520 530 540 550 560 570 pF1KA0 TRAFFRYGGEAQMRFPTTLPPPSNVGPILGSPVYSSSPVPSGSPYPNPSFLGTPSHGIQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRAFFRYGGEAQMRFPTTLPPPSNVGPILGSPVYSSSPVPSGSPYPNPSFLGTPSHGIQP 570 580 590 600 610 620 580 590 600 610 620 630 pF1KA0 PAMSTPVCALGNPATQATNMSCVTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERIFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAMSTPVCALGNPATQATNMSCVTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERIFK 630 640 650 660 670 680 640 650 660 670 680 690 pF1KA0 SGNREITAIESSVPCQLLESVLQELKGLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGNREITAIESSVPCQLLESVLQELKGLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFM 690 700 710 720 730 740 700 710 720 730 740 750 pF1KA0 RPENGNPQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTIIVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPENGNPQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTIIVAE 750 760 770 780 790 800 760 770 780 790 800 810 pF1KA0 LQKELQEQLKITTFKDLVIRDKELTGALIASLINCYIRDNAAVDGISLHLQDICPLLYST ::: NP_001 LQK--------------------------------------------------------- 810 820 830 840 850 860 870 pF1KA0 DDAICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEGV ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------ANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEGV 820 830 840 850 860 880 890 900 910 920 930 pF1KA0 VELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAA 870 880 890 900 910 920 940 950 960 970 980 990 pF1KA0 PQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLSQRSKDELFSIALYNWLIQVDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLSQRSKDELFSIALYNWLIQVDLA 930 940 950 960 970 980 1000 1010 1020 1030 1040 1050 pF1KA0 DKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTEI 990 1000 1010 1020 1030 1040 1060 1070 1080 1090 1100 1110 pF1KA0 SLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHS 1050 1060 1070 1080 1090 1100 1120 1130 1140 1150 1160 1170 pF1KA0 SVQDAVSQLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVQTLWQDIIEKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVQDAVSQLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVQTLWQDIIEKEL 1110 1120 1130 1140 1150 1160 1180 1190 1200 1210 1220 1230 pF1KA0 SDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTM 1170 1180 1190 1200 1210 1220 1240 1250 1260 1270 1280 1290 pF1KA0 NEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRF 1230 1240 1250 1260 1270 1280 1300 1310 1320 1330 pF1KA0 TNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH :::::::::::::::::::::::::::::::::::::::::: NP_001 TNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH 1290 1300 1310 1320 1332 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:19:35 2016 done: Thu Nov 3 10:19:37 2016 Total Scan time: 17.760 Total Display time: 0.250 Function used was FASTA [36.3.4 Apr, 2011]