FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0810, 812 aa 1>>>pF1KA0810 812 - 812 aa - 812 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6005+/-0.00105; mu= 8.9454+/- 0.062 mean_var=116.5921+/-23.973, 0's: 0 Z-trim(107.1): 27 B-trim: 0 in 0/51 Lambda= 0.118779 statistics sampled from 9368 (9384) to 9368 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.288), width: 16 Scan time: 4.340 The best scores are: opt bits E(32554) CCDS47525.1 SUN1 gene_id:23353|Hs108|chr7 ( 785) 3785 660.3 3.5e-189 CCDS43533.1 SUN1 gene_id:23353|Hs108|chr7 ( 702) 3548 619.7 5.4e-177 CCDS55080.1 SUN1 gene_id:23353|Hs108|chr7 ( 682) 3539 618.1 1.5e-176 CCDS55079.1 SUN1 gene_id:23353|Hs108|chr7 ( 257) 1456 261.0 1.8e-69 CCDS55078.1 SUN1 gene_id:23353|Hs108|chr7 ( 278) 1456 261.1 1.9e-69 CCDS13978.1 SUN2 gene_id:25777|Hs108|chr22 ( 717) 1036 189.2 2.1e-47 CCDS56231.1 SUN2 gene_id:25777|Hs108|chr22 ( 738) 1036 189.2 2.1e-47 CCDS64647.1 SUN3 gene_id:256979|Hs108|chr7 ( 345) 621 118.0 2.8e-26 CCDS34636.1 SUN3 gene_id:256979|Hs108|chr7 ( 357) 621 118.0 2.8e-26 CCDS13209.1 SUN5 gene_id:140732|Hs108|chr20 ( 379) 516 100.0 7.8e-21 CCDS13259.1 SPAG4 gene_id:6676|Hs108|chr20 ( 437) 490 95.6 2e-19 >>CCDS47525.1 SUN1 gene_id:23353|Hs108|chr7 (785 aa) initn: 5205 init1: 3763 opt: 3785 Z-score: 3509.8 bits: 660.3 E(32554): 3.5e-189 Smith-Waterman score: 5155; 96.4% identity (96.7% similar) in 812 aa overlap (1-812:1-785) 10 20 30 40 50 60 pF1KA0 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: CCDS47 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAH :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: CCDS47 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLW :::::::::::::::::::::::::::::::::::::::: CCDS47 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKC-------------------- 190 200 210 220 250 260 270 280 290 300 pF1KA0 HIWACAGYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTL ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 -------YFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTL 230 240 250 260 270 310 320 330 340 350 360 pF1KA0 ISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVD 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA0 DPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKL 340 350 360 370 380 390 430 440 450 460 470 480 pF1KA0 QARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQ 400 410 420 430 440 450 490 500 510 520 530 540 pF1KA0 KELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQV 460 470 480 490 500 510 550 560 570 580 590 600 pF1KA0 REMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 REMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLP 520 530 540 550 560 570 610 620 630 640 650 660 pF1KA0 TSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 TSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSET 580 590 600 610 620 630 670 680 690 700 710 720 pF1KA0 YETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 YETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTL 640 650 660 670 680 690 730 740 750 760 770 780 pF1KA0 EHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 EHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDT 700 710 720 730 740 750 790 800 810 pF1KA0 AFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK :::::::::::::::::::::::::::::::: CCDS47 AFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK 760 770 780 >>CCDS43533.1 SUN1 gene_id:23353|Hs108|chr7 (702 aa) initn: 4629 init1: 3548 opt: 3548 Z-score: 3291.1 bits: 619.7 E(32554): 5.4e-177 Smith-Waterman score: 4518; 91.9% identity (92.1% similar) in 762 aa overlap (51-812:1-702) 30 40 50 60 70 80 pF1KA0 YTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSA :::::::::::::::::::::::::::::: CCDS43 MSRRSLRLATTACTLGDGEAVGADSGTSSA 10 20 30 90 100 110 120 130 140 pF1KA0 VSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGGTVSLQDAVTRRPPVLDESWI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: CCDS43 VSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWI 40 50 60 70 80 90 150 160 170 180 190 200 pF1KA0 REQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAHNGFSCSNCSMLSERKDVLTA :::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: CCDS43 REQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAHNGFSCSNCSMLSERKDVLTA 100 110 120 130 140 150 210 220 230 240 250 260 pF1KA0 HPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLWHIWACAGYFLLQILRRIGAV ::::::::::::::::::: : CCDS43 HPAAPGPVSRVYSRDRNQK--------------------W-------------------- 160 170 270 280 290 300 310 320 pF1KA0 GQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFL :::::::::::::::::::::::::::::::::::::::: CCDS43 --------------------KAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFL 180 190 200 210 330 340 350 360 370 380 pF1KA0 VLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGD 220 230 240 250 260 270 390 400 410 420 430 440 pF1KA0 SEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRD 280 290 300 310 320 330 450 460 470 480 490 500 pF1KA0 AVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 AVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLP 340 350 360 370 380 390 510 520 530 540 550 560 pF1KA0 TVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQL 400 410 420 430 440 450 570 580 590 600 610 620 pF1KA0 LQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEA 460 470 480 490 500 510 630 640 650 660 670 680 pF1KA0 QARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQ 520 530 540 550 560 570 690 700 710 720 730 740 pF1KA0 SPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDF 580 590 600 610 620 630 750 760 770 780 790 800 pF1KA0 AVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 AVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTC 640 650 660 670 680 690 810 pF1KA0 LYRFRVHGEPVK :::::::::::: CCDS43 LYRFRVHGEPVK 700 >>CCDS55080.1 SUN1 gene_id:23353|Hs108|chr7 (682 aa) initn: 4177 init1: 3203 opt: 3539 Z-score: 3283.0 bits: 618.1 E(32554): 1.5e-176 Smith-Waterman score: 4250; 83.9% identity (84.0% similar) in 812 aa overlap (1-812:1-682) 10 20 30 40 50 60 pF1KA0 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: CCDS55 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAH ::::::::::::::::::::::::::::::: CCDS55 TVSLQDAVTRRPPVLDESWIREQTTVDHFWG----------------------------- 130 140 150 190 200 210 220 230 240 pF1KA0 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLW CCDS55 ------------------------------------------------------------ 250 260 270 280 290 300 pF1KA0 HIWACAGYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTL :::::::::::::::::::: CCDS55 ----------------------------------------KAASGVFWWLGIGWYQFVTL 160 170 310 320 330 340 350 360 pF1KA0 ISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVD :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: CCDS55 ISWLNVFLLTRCLRNICKFLVLLIPLFLLL-GLSLRGQGNFFSFLPVLNWASMHRTQRVD 180 190 200 210 220 230 370 380 390 400 410 420 pF1KA0 DPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKL 240 250 260 270 280 290 430 440 450 460 470 480 pF1KA0 QARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQ 300 310 320 330 340 350 490 500 510 520 530 540 pF1KA0 KELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQV 360 370 380 390 400 410 550 560 570 580 590 600 pF1KA0 REMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 REMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLP 420 430 440 450 460 470 610 620 630 640 650 660 pF1KA0 TSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 TSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSET 480 490 500 510 520 530 670 680 690 700 710 720 pF1KA0 YETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTL 540 550 560 570 580 590 730 740 750 760 770 780 pF1KA0 EHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 EHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDT 600 610 620 630 640 650 790 800 810 pF1KA0 AFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK :::::::::::::::::::::::::::::::: CCDS55 AFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK 660 670 680 >>CCDS55079.1 SUN1 gene_id:23353|Hs108|chr7 (257 aa) initn: 1456 init1: 1456 opt: 1456 Z-score: 1360.8 bits: 261.0 E(32554): 1.8e-69 Smith-Waterman score: 1456; 99.1% identity (100.0% similar) in 220 aa overlap (1-220:1-220) 10 20 30 40 50 60 pF1KA0 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: CCDS55 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAH :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: CCDS55 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLW :::::::::::::::::::::::::::::::::::::::: CCDS55 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCKSQSFKTQKKVCFPNLIFPF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 HIWACAGYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTL CCDS55 CKSQCLHYLSWRLKIIP 250 >>CCDS55078.1 SUN1 gene_id:23353|Hs108|chr7 (278 aa) initn: 1456 init1: 1456 opt: 1456 Z-score: 1360.2 bits: 261.1 E(32554): 1.9e-69 Smith-Waterman score: 1456; 99.1% identity (100.0% similar) in 220 aa overlap (1-220:22-241) 10 20 30 pF1KA0 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETE ::::::::::::::::::::::::::::::::::::::: CCDS55 MGRISPGSPGLPRTVWFEVVNMDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 HKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 SAFSINHVSRQVTSSGVSYGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLK ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: CCDS55 SAFSINHVSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLK 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 GGNKAAIQGNGDVGVAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQK ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GGNKAAIQGNGDVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQK 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 CDDCKGKRHLDAHPGRAGTLWHIWACAGYFLLQILRRIGAVGQAVSRTAWSALWLAVVAP : CCDS55 CKSQSFKTQKKVCFPNLIFPFCKSQCLHYLSWRLKIIP 250 260 270 >>CCDS13978.1 SUN2 gene_id:25777|Hs108|chr22 (717 aa) initn: 1150 init1: 757 opt: 1036 Z-score: 964.6 bits: 189.2 E(32554): 2.1e-47 Smith-Waterman score: 1215; 34.6% identity (60.4% similar) in 803 aa overlap (51-810:1-715) 30 40 50 60 70 80 pF1KA0 YTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSA ::::: :: : . :: .. ....:.: : CCDS13 MSRRSQRL--TRYSQGDDDGSSSSGGSSVA 10 20 90 100 110 120 130 pF1KA0 VS----LKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGGTVSLQDAVTRRPPVLD : .:. :: : :.:.: . .: . :. :. .. . : .. CCDS13 GSQSTLFKDSPLRTLK-RKSSNMKRLSP---APQLGPSSDAHTSYYS--------ESLVH 30 40 50 60 70 140 150 160 170 180 190 pF1KA0 ESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAHNGFSCSNCSMLSERKD :::. ....... :: . :. :. : . .: : : : :: CCDS13 ESWFPPRSSLEEL-----HGDANWGE--------DLRVRRRRGTGGSESSRASGLVGRKA 80 90 100 110 120 200 210 220 230 240 250 pF1KA0 VLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLWHIWACAGYFLLQILRR . .. : :: . :: : .: . . . :: CCDS13 TEDFLGSSSG-----YSSE-----DDYVGYSDVDQQSSSSR----------------LR- 130 140 150 260 270 280 290 300 310 pF1KA0 IGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNI .:::: : : ::.....::. ..:: : ::...: : :.::.::: . .. CCDS13 -----SAVSR-AGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSL 160 170 180 190 200 210 320 330 340 350 360 370 pF1KA0 CKFLVLLIPLFLLLAGLSLRGQGNFF-----SFLPVL-NWASMHRTQRVDDPQDVFKPTT :: .:.:: :::. :. : :. .: :.: .: . . ..: :. . CCDS13 KTFLWFLLPL-LLLTCLTY-GAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWE------ 220 230 240 250 260 380 390 400 410 420 pF1KA0 SRLKQP-LQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQM-E .: ..: .:..... :: :.. : . . . : .. . :..:. : . CCDS13 ARDSSPHFQAEQRV-----MSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQ 270 280 290 300 310 430 440 450 460 470 pF1KA0 GGAAGPS-----------ASVRDAVGQPPRETDFMAFHQEH--EVRMSHL---EDILGKL ::..: : .: :.:. . . . : ::. .: : ::.. :. CCDS13 GGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKI 320 330 340 350 360 370 480 490 500 510 520 pF1KA0 REKSEAIQKELEQTKQKTISAVGEQLLPT-VEHLQLELDQL---KSELSSWRHVKTGC-- . :. . ...: :.. : . :.. . :..:. ::: ..::.. ... CCDS13 VRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAE 380 390 400 410 420 430 530 540 550 560 570 580 pF1KA0 ------ETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRD . ..::.. :. : .. .... ::. :::: ..:..::. CCDS13 EVGLLPQQIQAVRDDVESQFPAWISQFLARG--GGGRVGLLQRE--------EMQAQLRE 440 450 460 470 480 590 600 610 620 630 pF1KA0 LQLQILRNVTHHVSVTKQLPTSEAVVS---AVSEAGASGITEAQARAIVNSALKLYSQDK :. .:: ::. . . ::..: .... :. :.:: :.. ::..::. ::.:. CCDS13 LESKILT----HVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDR 490 500 510 520 530 540 640 650 660 670 680 690 pF1KA0 TGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWA :..:.::::::.:..::::::::::::::.::::::::: ::::::..:::..:::::: CCDS13 IGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWA 550 560 570 580 590 600 700 710 720 730 740 750 pF1KA0 FKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLG :.: ::. ::::: :.:.: ::::.::.:::...:::::::::..:.... :.:: ::: CCDS13 FQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLG 610 620 630 640 650 660 760 770 780 790 800 810 pF1KA0 QFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK .:::::::: .: :. .. : ...:.:::::..:::::::::.::::::::: CCDS13 KFTYDQDGEPIQTFH-FQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH 670 680 690 700 710 >>CCDS56231.1 SUN2 gene_id:25777|Hs108|chr22 (738 aa) initn: 1150 init1: 757 opt: 1036 Z-score: 964.4 bits: 189.2 E(32554): 2.1e-47 Smith-Waterman score: 1249; 34.7% identity (61.4% similar) in 803 aa overlap (51-810:1-736) 30 40 50 60 70 80 pF1KA0 YTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSA ::::: :: : . :: .. ....:.: : CCDS56 MSRRSQRL--TRYSQGDDDGSSSSGGSSVA 10 20 90 100 110 120 130 pF1KA0 VS----LKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGGTVSLQDAVTRRPPVLD : .:. :: : :.:.: . .: . :. :. .. . : .. CCDS56 GSQSTLFKDSPLRTLK-RKSSNMKRLSP---APQLGPSSDAHTSYYS--------ESLVH 30 40 50 60 70 140 150 160 170 180 190 pF1KA0 ESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAHNGFSCSNCSMLSERKD :::. ....... :: . :. :. : . .: : : : :: CCDS56 ESWFPPRSSLEEL-----HGDANWGE--------DLRVRRRRGTGGSESSRASGLVGRK- 80 90 100 110 120 200 210 220 230 240 250 pF1KA0 VLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLWHIWACAGYFLLQILRR : : : :.: . .. .:.. ...: . ::: .. CCDS56 ---ATEDFLGSSSGYSSEDDYVEDSEGRGSKVTETEPVSSFP-------AGYSDVDQQSS 130 140 150 160 170 260 270 280 290 300 310 pF1KA0 IGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNI . . .:::: : : ::.....::. ..:: : ::...: : :.::.::: . .. CCDS56 SSRLRSAVSR-AGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSL 180 190 200 210 220 230 320 330 340 350 360 370 pF1KA0 CKFLVLLIPLFLLLAGLSLRGQGNFF-----SFLPVL-NWASMHRTQRVDDPQDVFKPTT :: .:.:: :::. :. : :. .: :.: .: . . ..: :. . CCDS56 KTFLWFLLPL-LLLTCLTY-GAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWE------ 240 250 260 270 280 380 390 400 410 420 pF1KA0 SRLKQP-LQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQM-E .: ..: .:..... :: :.. : . . . : .. . :..:. : . CCDS56 ARDSSPHFQAEQRV-----MSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQ 290 300 310 320 330 430 440 450 460 470 pF1KA0 GGAAGPS-----------ASVRDAVGQPPRETDFMAFHQEH--EVRMSHL---EDILGKL ::..: : .: :.:. . . . : ::. .: : ::.. :. CCDS56 GGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKI 340 350 360 370 380 390 480 490 500 510 520 pF1KA0 REKSEAIQKELEQTKQKTISAVGEQLLPT-VEHLQLELDQL---KSELSSWRHVKTGC-- . :. . ...: :.. : . :.. . :..:. ::: ..::.. ... CCDS56 VRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAE 400 410 420 430 440 450 530 540 550 560 570 580 pF1KA0 ------ETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRD . ..::.. :. : .. .... ::. :::: ..:..::. CCDS56 EVGLLPQQIQAVRDDVESQFPAWISQFLARG--GGGRVGLLQRE--------EMQAQLRE 460 470 480 490 500 590 600 610 620 630 pF1KA0 LQLQILRNVTHHVSVTKQLPTSEAVVS---AVSEAGASGITEAQARAIVNSALKLYSQDK :. .:: ::. . . ::..: .... :. :.:: :.. ::..::. ::.:. CCDS56 LESKILT----HVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDR 510 520 530 540 550 560 640 650 660 670 680 690 pF1KA0 TGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWA :..:.::::::.:..::::::::::::::.::::::::: ::::::..:::..:::::: CCDS56 IGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWA 570 580 590 600 610 620 700 710 720 730 740 750 pF1KA0 FKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLG :.: ::. ::::: :.:.: ::::.::.:::...:::::::::..:.... :.:: ::: CCDS56 FQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLG 630 640 650 660 670 680 760 770 780 790 800 810 pF1KA0 QFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK .:::::::: .: :. .. : ...:.:::::..:::::::::.::::::::: CCDS56 KFTYDQDGEPIQTFH-FQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH 690 700 710 720 730 >>CCDS64647.1 SUN3 gene_id:256979|Hs108|chr7 (345 aa) initn: 670 init1: 461 opt: 621 Z-score: 585.4 bits: 118.0 E(32554): 2.8e-26 Smith-Waterman score: 621; 47.3% identity (75.0% similar) in 188 aa overlap (625-812:157-343) 600 610 620 630 640 650 pF1KA0 VTKQLPTSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILS .:: .:: .:.. :.:.::.:.:.::. CCDS64 DMKDGMDNNHNWNTHGDPVEDPDHTEEVSNLVNYVLKKLREDQVEMADYALKSAGASIIE 130 140 150 160 170 180 660 670 680 690 700 710 pF1KA0 TRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIH . ::.:... : . :: . . : ...:::.:::.:::: ::::. ...:. : CCDS64 AGTSESYKNNKAKLYWHGIGFLNHEMPPDIILQPDVYPGKCWAFPGSQGHTLIKLATKII 190 200 210 220 230 240 720 730 740 750 760 770 pF1KA0 PAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQAL :.: :.::: . .::.::::::::.:.:::. .. . : .:::: :.. : ..: :. : CCDS64 PTAVTMEHISEKVSPSGNISSAPKEFSVYGITKKCEGEEIFLGQFIYNKTGTTVQTFE-L 250 260 270 280 290 300 780 790 800 810 pF1KA0 KRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK .. . . :.: ::::::::.::::::::::: : : CCDS64 QHAVSEYLLCVKLNIFSNWGHPKYTCLYRFRVHGTPGKHI 310 320 330 340 >>CCDS34636.1 SUN3 gene_id:256979|Hs108|chr7 (357 aa) initn: 645 init1: 461 opt: 621 Z-score: 585.2 bits: 118.0 E(32554): 2.8e-26 Smith-Waterman score: 621; 47.3% identity (75.0% similar) in 188 aa overlap (625-812:169-355) 600 610 620 630 640 650 pF1KA0 VTKQLPTSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILS .:: .:: .:.. :.:.::.:.:.::. CCDS34 DMKDGMDNNHNWNTHGDPVEDPDHTEEVSNLVNYVLKKLREDQVEMADYALKSAGASIIE 140 150 160 170 180 190 660 670 680 690 700 710 pF1KA0 TRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIH . ::.:... : . :: . . : ...:::.:::.:::: ::::. ...:. : CCDS34 AGTSESYKNNKAKLYWHGIGFLNHEMPPDIILQPDVYPGKCWAFPGSQGHTLIKLATKII 200 210 220 230 240 250 720 730 740 750 760 770 pF1KA0 PAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQAL :.: :.::: . .::.::::::::.:.:::. .. . : .:::: :.. : ..: :. : CCDS34 PTAVTMEHISEKVSPSGNISSAPKEFSVYGITKKCEGEEIFLGQFIYNKTGTTVQTFE-L 260 270 280 290 300 310 780 790 800 810 pF1KA0 KRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK .. . . :.: ::::::::.::::::::::: : : CCDS34 QHAVSEYLLCVKLNIFSNWGHPKYTCLYRFRVHGTPGKHI 320 330 340 350 >>CCDS13209.1 SUN5 gene_id:140732|Hs108|chr20 (379 aa) initn: 494 init1: 345 opt: 516 Z-score: 487.5 bits: 100.0 E(32554): 7.8e-21 Smith-Waterman score: 516; 38.2% identity (66.4% similar) in 238 aa overlap (572-808:136-361) 550 560 570 580 590 600 pF1KA0 EMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPT : ::. :: : ..: :: . ..: CCDS13 GILLLCAFGFWMFSIHLPSKMKVWQDDSINGPLQS-LRLYQ----EKVRHHSGEIQDLRG 110 120 130 140 150 160 610 620 630 640 650 660 pF1KA0 S-EAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSET : . ... ..: : . . .:. : .:. : ::::.: :.:: . : : CCDS13 SMNQLIAKLQEMEAMSDEQKMAQKI----MKMIHGDYIEKPDFALKSIGASIDFEHTSVT 170 180 190 200 210 670 680 690 700 710 720 pF1KA0 YETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTL :. . : : :: ..: : :...:.. :::::::.:..: ....:.. .. . .:: CCDS13 YNHEKAHSYWNWIQLWNYAQPPDVILEPNVTPGNCWAFEGDRGQVTIQLAQKVYLSNLTL 220 230 240 250 260 270 730 740 750 760 770 780 pF1KA0 EHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDT .:::::.: .:....:::::..::.:. .:: .:: : . : . .::: ..: CCDS13 QHIPKTISLSGSLDTAPKDFVIYGMEGSPKEE-VFLGAFQF-QPENIIQMFPLQNQPA-R 280 290 300 310 320 330 790 800 810 pF1KA0 AFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK ::. :...: ::::.: .::::: :::: CCDS13 AFSAVKVKISSNWGNPGFTCLYRVRVHGSVAPPREQPHQNPYPKRD 340 350 360 370 812 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:02:05 2016 done: Fri Nov 4 01:02:05 2016 Total Scan time: 4.340 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]