FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0815, 1229 aa
1>>>pF1KA0815 1229 - 1229 aa - 1229 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3724+/-0.000569; mu= 14.6733+/- 0.035
mean_var=318.9808+/-64.457, 0's: 0 Z-trim(117.0): 644 B-trim: 71 in 1/52
Lambda= 0.071811
statistics sampled from 27940 (28713) to 27940 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.337), width: 16
Scan time: 13.340
The best scores are: opt bits E(85289)
XP_006710469 (OMIM: 604266) PREDICTED: multiple ep (1436) 8125 857.8 0
NP_001400 (OMIM: 604266) multiple epidermal growth (1541) 7722 816.1 0
XP_011539188 (OMIM: 604266) PREDICTED: multiple ep (1560) 7722 816.1 0
XP_011539187 (OMIM: 604266) PREDICTED: multiple ep (1603) 7722 816.2 0
XP_011539190 (OMIM: 604266) PREDICTED: multiple ep (1364) 7707 814.5 0
XP_011539189 (OMIM: 604266) PREDICTED: multiple ep (1395) 7401 782.8 0
XP_016856022 (OMIM: 604266) PREDICTED: multiple ep (1559) 5473 583.1 4.7e-165
XP_016878162 (OMIM: 612454) PREDICTED: multiple ep (1021) 2348 259.1 1.1e-67
NP_115821 (OMIM: 612454) multiple epidermal growth (1044) 2348 259.1 1.1e-67
XP_016878161 (OMIM: 612454) PREDICTED: multiple ep (1044) 2348 259.1 1.1e-67
XP_016878160 (OMIM: 612454) PREDICTED: multiple ep (1092) 2348 259.2 1.1e-67
NP_001243474 (OMIM: 612453,614399) multiple epider (1140) 2331 257.4 3.9e-67
XP_011541996 (OMIM: 612453,614399) PREDICTED: mult (1140) 2331 257.4 3.9e-67
NP_115822 (OMIM: 612453,614399) multiple epidermal (1140) 2331 257.4 3.9e-67
XP_016865476 (OMIM: 612453,614399) PREDICTED: mult (1195) 2331 257.5 4e-67
XP_016856726 (OMIM: 610278) PREDICTED: platelet en ( 973) 2154 239.0 1.2e-61
XP_016856728 (OMIM: 610278) PREDICTED: platelet en ( 973) 2154 239.0 1.2e-61
XP_016856727 (OMIM: 610278) PREDICTED: platelet en ( 973) 2154 239.0 1.2e-61
XP_011507813 (OMIM: 610278) PREDICTED: platelet en (1002) 2154 239.0 1.2e-61
XP_011507812 (OMIM: 610278) PREDICTED: platelet en (1037) 2154 239.0 1.2e-61
XP_016856725 (OMIM: 610278) PREDICTED: platelet en (1037) 2154 239.0 1.2e-61
NP_001073940 (OMIM: 610278) platelet endothelial a (1037) 2154 239.0 1.2e-61
XP_005245198 (OMIM: 610278) PREDICTED: platelet en (1037) 2154 239.0 1.2e-61
XP_016856723 (OMIM: 610278) PREDICTED: platelet en (1125) 2154 239.1 1.3e-61
XP_016878159 (OMIM: 612454) PREDICTED: multiple ep (1097) 1965 219.5 9.8e-56
XP_016856729 (OMIM: 610278) PREDICTED: platelet en ( 909) 1954 218.2 2e-55
XP_016856730 (OMIM: 610278) PREDICTED: platelet en ( 909) 1954 218.2 2e-55
XP_016856731 (OMIM: 610278) PREDICTED: platelet en ( 909) 1954 218.2 2e-55
XP_016856724 (OMIM: 610278) PREDICTED: platelet en (1081) 1848 207.3 4.3e-52
XP_011507814 (OMIM: 610278) PREDICTED: platelet en ( 868) 1808 203.1 6.8e-51
XP_016878163 (OMIM: 612454) PREDICTED: multiple ep ( 854) 1342 154.8 2.3e-36
XP_016878164 (OMIM: 612454) PREDICTED: multiple ep ( 854) 1342 154.8 2.3e-36
NP_001295048 (OMIM: 612453,614399) multiple epider ( 567) 1288 148.9 9e-35
NP_001295050 (OMIM: 612453,614399) multiple epider ( 567) 1288 148.9 9e-35
XP_005259981 (OMIM: 125310,130720,600276,615293) P (2269) 1118 132.2 3.8e-29
XP_011517019 (OMIM: 109730,190198,616028) PREDICTE (2314) 1077 128.0 7.2e-28
NP_060087 (OMIM: 109730,190198,616028) neurogenic (2555) 1077 128.1 7.6e-28
XP_016882866 (OMIM: 608529) PREDICTED: fibrillin-3 (1948) 1066 126.7 1.4e-27
NP_000129 (OMIM: 102370,129600,134797,154700,18490 (2871) 1062 126.6 2.4e-27
XP_016865477 (OMIM: 612453,614399) PREDICTED: mult ( 760) 986 117.8 2.8e-25
XP_016882864 (OMIM: 608529) PREDICTED: fibrillin-3 (2768) 993 119.4 3.3e-25
NP_000426 (OMIM: 125310,130720,600276,615293) neur (2321) 975 117.4 1.1e-24
XP_016882865 (OMIM: 608529) PREDICTED: fibrillin-3 (2766) 948 114.7 8.4e-24
XP_016882863 (OMIM: 608529) PREDICTED: fibrillin-3 (2777) 948 114.7 8.4e-24
XP_016882862 (OMIM: 608529) PREDICTED: fibrillin-3 (2789) 948 114.7 8.4e-24
XP_016882861 (OMIM: 608529) PREDICTED: fibrillin-3 (2809) 948 114.8 8.4e-24
NP_001308360 (OMIM: 608529) fibrillin-3 precursor (2809) 948 114.8 8.4e-24
NP_115823 (OMIM: 608529) fibrillin-3 precursor [Ho (2809) 948 114.8 8.4e-24
XP_016882868 (OMIM: 608529) PREDICTED: fibrillin-3 (2851) 948 114.8 8.5e-24
XP_016864717 (OMIM: 121050,612570,616118) PREDICTE (2861) 932 113.1 2.7e-23
>>XP_006710469 (OMIM: 604266) PREDICTED: multiple epider (1436 aa)
initn: 9616 init1: 7674 opt: 8125 Z-score: 4569.5 bits: 857.8 E(85289): 0
Smith-Waterman score: 8738; 89.4% identity (89.6% similar) in 1261 aa overlap (1-1131:1-1261)
10 20 30 40 50 60
pF1KA0 MGASRDRGLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQRPDVDEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGASRDRGLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQRPDVDEC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 PFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 FGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 ACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 SGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEH
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_006 SGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEH
790 800 810 820 830 840
850 860 870 880
pF1KA0 ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------
:::::::::::::::::::::::::::::::::::::::::::
XP_006 ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACAC
850 860 870 880 890 900
pF1KA0 ------------------------------------------------------------
XP_006 FNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPE
910 920 930 940 950 960
890 900 910 920 930
pF1KA0 ---------KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG
.::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG
970 980 990 1000 1010 1020
940 950 960 970
pF1KA0 EACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------
:::::::::::.:::::::::::::::::::::::.::::
XP_006 EACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACH
1030 1040 1050 1060 1070 1080
980 990 1000 1010
pF1KA0 ------------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC
::::::::::::::::::::::::::::::::::::
XP_006 PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC
1090 1100 1110 1120 1130 1140
1020 1030 1040 1050 1060 1070
pF1KA0 NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTC
1150 1160 1170 1180 1190 1200
1080 1090 1100 1110 1120 1130
pF1KA0 SCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRC
1210 1220 1230 1240 1250 1260
1140 1150 1160 1170 1180 1190
pF1KA0 GPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPT
:
XP_006 GPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGS
1270 1280 1290 1300 1310 1320
>--
initn: 1507 init1: 663 opt: 969 Z-score: 562.8 bits: 116.5 E(85289): 1.3e-24
Smith-Waterman score: 969; 67.4% identity (78.3% similar) in 184 aa overlap (1046-1229:1262-1436)
1020 1030 1040 1050 1060 1070
pF1KA0 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG
:: : ::. :: . :.::. : :..:
XP_006 PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG
1240 1250 1260 1270 1280 1290
1080 1090 1100 1110 1120 1130
pF1KA0 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY
. : .: : : :. :. :: .: :: .: .:: .:.: ... :.:.:: : : ::
XP_006 APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG--
1300 1310 1320 1330 1340
1140 1150 1160 1170 1180 1190
pF1KA0 GQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 -------RSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
1350 1360 1370 1380 1390 1400
1200 1210 1220
pF1KA0 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
::::::::::::::::::::::::::::::::::
XP_006 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
1410 1420 1430
>>NP_001400 (OMIM: 604266) multiple epidermal growth fac (1541 aa)
initn: 9206 init1: 7264 opt: 7722 Z-score: 4343.6 bits: 816.1 E(85289): 0
Smith-Waterman score: 8335; 87.9% identity (88.3% similar) in 1225 aa overlap (38-1131:146-1366)
10 20 30 40 50 60
pF1KA0 GLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQ-RPDVDECRTHNGG
::: : : . . :::::::::::
NP_001 QQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCP----PGFQGPRCQYDVDECRTHNGG
120 130 140 150 160 170
70 80 90 100 110 120
pF1KA0 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
180 190 200 210 220 230
130 140 150 160 170 180
pF1KA0 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
240 250 260 270 280 290
190 200 210 220 230 240
pF1KA0 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
300 310 320 330 340 350
250 260 270 280 290 300
pF1KA0 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
360 370 380 390 400 410
310 320 330 340 350 360
pF1KA0 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
420 430 440 450 460 470
370 380 390 400 410 420
pF1KA0 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
480 490 500 510 520 530
430 440 450 460 470 480
pF1KA0 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
540 550 560 570 580 590
490 500 510 520 530 540
pF1KA0 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
600 610 620 630 640 650
550 560 570 580 590 600
pF1KA0 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
660 670 680 690 700 710
610 620 630 640 650 660
pF1KA0 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
720 730 740 750 760 770
670 680 690 700 710 720
pF1KA0 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
780 790 800 810 820 830
730 740 750 760 770 780
pF1KA0 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
840 850 860 870 880 890
790 800 810 820 830 840
pF1KA0 EAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
NP_001 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
900 910 920 930 940 950
850 860 870 880
pF1KA0 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------------
:::::::::::::::::::::::::::::::::::::
NP_001 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC
960 970 980 990 1000 1010
pF1KA0 ------------------------------------------------------------
NP_001 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA
1020 1030 1040 1050 1060 1070
890 900 910 920 930 940
pF1KA0 ---KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
1080 1090 1100 1110 1120 1130
950 960 970
pF1KA0 CSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------------
:::::.:::::::::::::::::::::::.::::
NP_001 CSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC
1140 1150 1160 1170 1180 1190
980 990 1000 1010
pF1KA0 ------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
::::::::::::::::::::::::::::::::::::::::::
NP_001 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
1200 1210 1220 1230 1240 1250
1020 1030 1040 1050 1060 1070
pF1KA0 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
1260 1270 1280 1290 1300 1310
1080 1090 1100 1110 1120 1130
pF1KA0 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
1320 1330 1340 1350 1360 1370
1140 1150 1160 1170 1180 1190
pF1KA0 QACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP
NP_001 QACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCH
1380 1390 1400 1410 1420 1430
>--
initn: 1507 init1: 663 opt: 969 Z-score: 562.5 bits: 116.5 E(85289): 1.4e-24
Smith-Waterman score: 969; 67.4% identity (78.3% similar) in 184 aa overlap (1046-1229:1367-1541)
1020 1030 1040 1050 1060 1070
pF1KA0 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG
:: : ::. :: . :.::. : :..:
NP_001 PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG
1340 1350 1360 1370 1380 1390
1080 1090 1100 1110 1120 1130
pF1KA0 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY
. : .: : : :. :. :: .: :: .: .:: .:.: ... :.:.:: : : ::
NP_001 APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG--
1400 1410 1420 1430 1440 1450
1140 1150 1160 1170 1180 1190
pF1KA0 GQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------RSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
1460 1470 1480 1490 1500
1200 1210 1220
pF1KA0 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
::::::::::::::::::::::::::::::::::
NP_001 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
1510 1520 1530 1540
>>XP_011539188 (OMIM: 604266) PREDICTED: multiple epider (1560 aa)
initn: 7872 init1: 7264 opt: 7722 Z-score: 4343.5 bits: 816.1 E(85289): 0
Smith-Waterman score: 8335; 87.9% identity (88.3% similar) in 1225 aa overlap (38-1131:208-1428)
10 20 30 40 50 60
pF1KA0 GLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQ-RPDVDECRTHNGG
::: : : . . :::::::::::
XP_011 QQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCP----PGFQGPRCQYDVDECRTHNGG
180 190 200 210 220 230
70 80 90 100 110 120
pF1KA0 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
240 250 260 270 280 290
130 140 150 160 170 180
pF1KA0 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
300 310 320 330 340 350
190 200 210 220 230 240
pF1KA0 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
360 370 380 390 400 410
250 260 270 280 290 300
pF1KA0 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
420 430 440 450 460 470
310 320 330 340 350 360
pF1KA0 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
480 490 500 510 520 530
370 380 390 400 410 420
pF1KA0 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
540 550 560 570 580 590
430 440 450 460 470 480
pF1KA0 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
600 610 620 630 640 650
490 500 510 520 530 540
pF1KA0 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
660 670 680 690 700 710
550 560 570 580 590 600
pF1KA0 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
720 730 740 750 760 770
610 620 630 640 650 660
pF1KA0 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
780 790 800 810 820 830
670 680 690 700 710 720
pF1KA0 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
840 850 860 870 880 890
730 740 750 760 770 780
pF1KA0 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
900 910 920 930 940 950
790 800 810 820 830 840
pF1KA0 EAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
960 970 980 990 1000 1010
850 860 870 880
pF1KA0 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------------
:::::::::::::::::::::::::::::::::::::
XP_011 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC
1020 1030 1040 1050 1060 1070
pF1KA0 ------------------------------------------------------------
XP_011 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA
1080 1090 1100 1110 1120 1130
890 900 910 920 930 940
pF1KA0 ---KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
1140 1150 1160 1170 1180 1190
950 960 970
pF1KA0 CSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------------
:::::.:::::::::::::::::::::::.::::
XP_011 CSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC
1200 1210 1220 1230 1240 1250
980 990 1000 1010
pF1KA0 ------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
::::::::::::::::::::::::::::::::::::::::::
XP_011 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
1260 1270 1280 1290 1300 1310
1020 1030 1040 1050 1060 1070
pF1KA0 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
1320 1330 1340 1350 1360 1370
1080 1090 1100 1110 1120 1130
pF1KA0 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
1380 1390 1400 1410 1420 1430
1140 1150 1160 1170 1180 1190
pF1KA0 QACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP
XP_011 QACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERDCRRGQFGPSCT
1440 1450 1460 1470 1480 1490
>--
initn: 846 init1: 622 opt: 789 Z-score: 461.7 bits: 97.9 E(85289): 5.6e-19
Smith-Waterman score: 789; 72.9% identity (82.9% similar) in 140 aa overlap (1090-1229:1430-1560)
1060 1070 1080 1090 1100 1110
pF1KA0 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNS
:. :. :: :::: .::.:. : :....
XP_011 GRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGA
1400 1410 1420 1430 1440 1450
1120 1130 1140 1150 1160 1170
pF1KA0 TCEPATGTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ
:.: .: : : ::.:. ::. :::::::::::::::::::::::::::::
XP_011 PCDPISGRCLCPAGFHGHFCER---------DCRRGQFGPSCTLHCDCGGGADCDPVSGQ
1460 1470 1480 1490 1500 1510
1180 1190 1200 1210 1220
pF1KA0 CHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
1520 1530 1540 1550 1560
>>XP_011539187 (OMIM: 604266) PREDICTED: multiple epider (1603 aa)
initn: 9206 init1: 7264 opt: 7722 Z-score: 4343.4 bits: 816.2 E(85289): 0
Smith-Waterman score: 8335; 87.9% identity (88.3% similar) in 1225 aa overlap (38-1131:208-1428)
10 20 30 40 50 60
pF1KA0 GLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQ-RPDVDECRTHNGG
::: : : . . :::::::::::
XP_011 QQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCP----PGFQGPRCQYDVDECRTHNGG
180 190 200 210 220 230
70 80 90 100 110 120
pF1KA0 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
240 250 260 270 280 290
130 140 150 160 170 180
pF1KA0 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
300 310 320 330 340 350
190 200 210 220 230 240
pF1KA0 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
360 370 380 390 400 410
250 260 270 280 290 300
pF1KA0 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
420 430 440 450 460 470
310 320 330 340 350 360
pF1KA0 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
480 490 500 510 520 530
370 380 390 400 410 420
pF1KA0 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
540 550 560 570 580 590
430 440 450 460 470 480
pF1KA0 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
600 610 620 630 640 650
490 500 510 520 530 540
pF1KA0 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
660 670 680 690 700 710
550 560 570 580 590 600
pF1KA0 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
720 730 740 750 760 770
610 620 630 640 650 660
pF1KA0 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
780 790 800 810 820 830
670 680 690 700 710 720
pF1KA0 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
840 850 860 870 880 890
730 740 750 760 770 780
pF1KA0 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
900 910 920 930 940 950
790 800 810 820 830 840
pF1KA0 EAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
960 970 980 990 1000 1010
850 860 870 880
pF1KA0 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------------
:::::::::::::::::::::::::::::::::::::
XP_011 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC
1020 1030 1040 1050 1060 1070
pF1KA0 ------------------------------------------------------------
XP_011 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA
1080 1090 1100 1110 1120 1130
890 900 910 920 930 940
pF1KA0 ---KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
1140 1150 1160 1170 1180 1190
950 960 970
pF1KA0 CSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------------
:::::.:::::::::::::::::::::::.::::
XP_011 CSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC
1200 1210 1220 1230 1240 1250
980 990 1000 1010
pF1KA0 ------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
::::::::::::::::::::::::::::::::::::::::::
XP_011 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
1260 1270 1280 1290 1300 1310
1020 1030 1040 1050 1060 1070
pF1KA0 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
1320 1330 1340 1350 1360 1370
1080 1090 1100 1110 1120 1130
pF1KA0 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
1380 1390 1400 1410 1420 1430
1140 1150 1160 1170 1180 1190
pF1KA0 QACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP
XP_011 QACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCH
1440 1450 1460 1470 1480 1490
>--
initn: 1507 init1: 663 opt: 969 Z-score: 562.4 bits: 116.5 E(85289): 1.4e-24
Smith-Waterman score: 969; 67.4% identity (78.3% similar) in 184 aa overlap (1046-1229:1429-1603)
1020 1030 1040 1050 1060 1070
pF1KA0 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG
:: : ::. :: . :.::. : :..:
XP_011 PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG
1400 1410 1420 1430 1440 1450
1080 1090 1100 1110 1120 1130
pF1KA0 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY
. : .: : : :. :. :: .: :: .: .:: .:.: ... :.:.:: : : ::
XP_011 APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG--
1460 1470 1480 1490 1500 1510
1140 1150 1160 1170 1180 1190
pF1KA0 GQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------RSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
1520 1530 1540 1550 1560
1200 1210 1220
pF1KA0 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
::::::::::::::::::::::::::::::::::
XP_011 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
1570 1580 1590 1600
>>XP_011539190 (OMIM: 604266) PREDICTED: multiple epider (1364 aa)
initn: 7264 init1: 7264 opt: 7707 Z-score: 4335.7 bits: 814.5 E(85289): 0
Smith-Waterman score: 7724; 83.0% identity (88.4% similar) in 1174 aa overlap (38-1209:208-1362)
10 20 30 40 50 60
pF1KA0 GLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQ-RPDVDECRTHNGG
::: : : . . :::::::::::
XP_011 QQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCP----PGFQGPRCQYDVDECRTHNGG
180 190 200 210 220 230
70 80 90 100 110 120
pF1KA0 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
240 250 260 270 280 290
130 140 150 160 170 180
pF1KA0 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
300 310 320 330 340 350
190 200 210 220 230 240
pF1KA0 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
360 370 380 390 400 410
250 260 270 280 290 300
pF1KA0 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
420 430 440 450 460 470
310 320 330 340 350 360
pF1KA0 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
480 490 500 510 520 530
370 380 390 400 410 420
pF1KA0 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
540 550 560 570 580 590
430 440 450 460 470 480
pF1KA0 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
600 610 620 630 640 650
490 500 510 520 530 540
pF1KA0 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
660 670 680 690 700 710
550 560 570 580 590 600
pF1KA0 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
720 730 740 750 760 770
610 620 630 640 650 660
pF1KA0 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
780 790 800 810 820 830
670 680 690 700 710 720
pF1KA0 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
840 850 860 870 880 890
730 740 750 760 770 780
pF1KA0 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
900 910 920 930 940 950
790 800 810 820 830 840
pF1KA0 EAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
960 970 980 990 1000 1010
850 860 870 880 890 900
pF1KA0 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLC
::::::::::::::::::::::::::::::::::::: : . .: .. .:.::. :
XP_011 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC
1020 1030 1040 1050 1060 1070
910 920 930 940 950 960
pF1KA0 DPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGACRCPPGFTGSG
:: :.: : :: : .: . : : .:. : . : : ...: :.: : :: :..: .
XP_011 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA
1080 1090 1100 1110 1120 1130
970 980 990 1000 1010 1020
pF1KA0 CEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHV
::. : : ::.. :::::: :: :: : ::.:. : :. : .: :: :..
XP_011 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
1140 1150 1160 1170 1180 1190
1030 1040 1050 1060 1070 1080
pF1KA0 CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRN-GGLCHASNGSC
:.: :::: :::.: :::: .: ::..:: . :: : . :.: . . :: ..:.:
XP_011 CSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC
1200 1210 1220 1230 1240 1250
1090 1100 1110 1120 1130 1140
pF1KA0 SCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHRRSG
::. :. : :. ::::::: .:. :.: :...:. :::.::: :: :
XP_011 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL---------G
1260 1270 1280 1290 1300
1150 1160 1170 1180 1190 1200
pF1KA0 ATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENPSL
. ::: : .:.:::.:: : :: :: ::::.: : : : : :. :.:. :.:
XP_011 TDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCE-----RVPR-PGL
1310 1320 1330 1340 1350
1210 1220
pF1KA0 AQGSAGTLPASSRPTSRSGGPARH
: ::
XP_011 ALGSLR
1360
>>XP_011539189 (OMIM: 604266) PREDICTED: multiple epider (1395 aa)
initn: 8884 init1: 6942 opt: 7401 Z-score: 4164.3 bits: 782.8 E(85289): 0
Smith-Waterman score: 8324; 86.1% identity (86.4% similar) in 1261 aa overlap (1-1131:1-1220)
10 20 30 40 50 60
pF1KA0 MGASRDRGLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQRPDVDEC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGASRDRGLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQRP-----
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 RTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH
::::::::::::::::::::::::
XP_011 ------------------------------------AINSCALGNGGCQHHCVQLTITRH
60 70
130 140 150 160 170 180
pF1KA0 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED
80 90 100 110 120 130
190 200 210 220 230 240
pF1KA0 VDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG
140 150 160 170 180 190
250 260 270 280 290 300
pF1KA0 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSA
200 210 220 230 240 250
310 320 330 340 350 360
pF1KA0 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGEL
260 270 280 290 300 310
370 380 390 400 410 420
pF1KA0 PFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCD
320 330 340 350 360 370
430 440 450 460 470 480
pF1KA0 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC
380 390 400 410 420 430
490 500 510 520 530 540
pF1KA0 PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWA
440 450 460 470 480 490
550 560 570 580 590 600
pF1KA0 FGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGV
500 510 520 530 540 550
610 620 630 640 650 660
pF1KA0 ACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRT
560 570 580 590 600 610
670 680 690 700 710 720
pF1KA0 GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPS
620 630 640 650 660 670
730 740 750 760 770 780
pF1KA0 CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI
680 690 700 710 720 730
790 800 810 820 830 840
pF1KA0 SGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEH
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_011 SGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEH
740 750 760 770 780 790
850 860 870 880
pF1KA0 ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------
:::::::::::::::::::::::::::::::::::::::::::
XP_011 ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACAC
800 810 820 830 840 850
pF1KA0 ------------------------------------------------------------
XP_011 FNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPE
860 870 880 890 900 910
890 900 910 920 930
pF1KA0 ---------KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG
.::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG
920 930 940 950 960 970
940 950 960 970
pF1KA0 EACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------
:::::::::::.:::::::::::::::::::::::.::::
XP_011 EACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACH
980 990 1000 1010 1020 1030
980 990 1000 1010
pF1KA0 ------------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC
::::::::::::::::::::::::::::::::::::
XP_011 PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC
1040 1050 1060 1070 1080 1090
1020 1030 1040 1050 1060 1070
pF1KA0 NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTC
1100 1110 1120 1130 1140 1150
1080 1090 1100 1110 1120 1130
pF1KA0 SCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRC
1160 1170 1180 1190 1200 1210
1140 1150 1160 1170 1180 1190
pF1KA0 GPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPT
:
XP_011 GPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGS
1220 1230 1240 1250 1260 1270
>--
initn: 1507 init1: 663 opt: 969 Z-score: 562.9 bits: 116.5 E(85289): 1.3e-24
Smith-Waterman score: 969; 67.4% identity (78.3% similar) in 184 aa overlap (1046-1229:1221-1395)
1020 1030 1040 1050 1060 1070
pF1KA0 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG
:: : ::. :: . :.::. : :..:
XP_011 PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG
1200 1210 1220 1230 1240 1250
1080 1090 1100 1110 1120 1130
pF1KA0 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY
. : .: : : :. :. :: .: :: .: .:: .:.: ... :.:.:: : : ::
XP_011 APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG--
1260 1270 1280 1290 1300
1140 1150 1160 1170 1180 1190
pF1KA0 GQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------RSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
1310 1320 1330 1340 1350 1360
1200 1210 1220
pF1KA0 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
::::::::::::::::::::::::::::::::::
XP_011 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
1370 1380 1390
>>XP_016856022 (OMIM: 604266) PREDICTED: multiple epider (1559 aa)
initn: 6201 init1: 4259 opt: 5473 Z-score: 3084.3 bits: 583.1 E(85289): 4.7e-165
Smith-Waterman score: 7875; 84.2% identity (84.7% similar) in 1225 aa overlap (38-1131:208-1384)
10 20 30 40 50 60
pF1KA0 GLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQ-RPDVDECRTHNGG
::: : : . . :::::::::::
XP_016 QQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCP----PGFQGPRCQYDVDECRTHNGG
180 190 200 210 220 230
70 80 90 100 110 120
pF1KA0 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
240 250 260 270 280 290
130 140 150 160 170 180
pF1KA0 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
300 310 320 330 340 350
190 200 210 220 230 240
pF1KA0 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
360 370 380 390 400 410
250 260 270 280 290 300
pF1KA0 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
420 430 440 450 460 470
310 320 330 340 350 360
pF1KA0 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
480 490 500 510 520 530
370 380 390 400 410 420
pF1KA0 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
::::::::::::::::::::::::::::::::::::::.:
XP_016 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFAC--------------------
540 550 560 570
430 440 450 460 470 480
pF1KA0 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
::::::::::::::::::::::::::::::::::::
XP_016 ------------------------PPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
580 590 600
490 500 510 520 530 540
pF1KA0 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
610 620 630 640 650 660
550 560 570 580 590 600
pF1KA0 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
670 680 690 700 710 720
610 620 630 640 650 660
pF1KA0 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
730 740 750 760 770 780
670 680 690 700 710 720
pF1KA0 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
790 800 810 820 830 840
730 740 750 760 770 780
pF1KA0 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
850 860 870 880 890 900
790 800 810 820 830 840
pF1KA0 EAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
910 920 930 940 950 960
850 860 870 880
pF1KA0 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------------
:::::::::::::::::::::::::::::::::::::
XP_016 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC
970 980 990 1000 1010 1020
pF1KA0 ------------------------------------------------------------
XP_016 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA
1030 1040 1050 1060 1070 1080
890 900 910 920 930 940
pF1KA0 ---KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
1090 1100 1110 1120 1130 1140
950 960 970
pF1KA0 CSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------------
:::::.:::::::::::::::::::::::.::::
XP_016 CSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC
1150 1160 1170 1180 1190 1200
980 990 1000 1010
pF1KA0 ------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
::::::::::::::::::::::::::::::::::::::::::
XP_016 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
1210 1220 1230 1240 1250 1260
1020 1030 1040 1050 1060 1070
pF1KA0 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
1270 1280 1290 1300 1310 1320
1080 1090 1100 1110 1120 1130
pF1KA0 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
1330 1340 1350 1360 1370 1380
1140 1150 1160 1170 1180 1190
pF1KA0 QACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP
XP_016 QACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCH
1390 1400 1410 1420 1430 1440
>--
initn: 1507 init1: 663 opt: 969 Z-score: 562.5 bits: 116.5 E(85289): 1.4e-24
Smith-Waterman score: 969; 67.4% identity (78.3% similar) in 184 aa overlap (1046-1229:1385-1559)
1020 1030 1040 1050 1060 1070
pF1KA0 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG
:: : ::. :: . :.::. : :..:
XP_016 PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG
1360 1370 1380 1390 1400 1410
1080 1090 1100 1110 1120 1130
pF1KA0 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY
. : .: : : :. :. :: .: :: .: .:: .:.: ... :.:.:: : : ::
XP_016 APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG--
1420 1430 1440 1450 1460 1470
1140 1150 1160 1170 1180 1190
pF1KA0 GQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -------RSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
1480 1490 1500 1510 1520
1200 1210 1220
pF1KA0 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
::::::::::::::::::::::::::::::::::
XP_016 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
1530 1540 1550
>>XP_016878162 (OMIM: 612454) PREDICTED: multiple epider (1021 aa)
initn: 2696 init1: 1026 opt: 2348 Z-score: 1336.3 bits: 259.1 E(85289): 1.1e-67
Smith-Waterman score: 2650; 40.8% identity (60.5% similar) in 812 aa overlap (341-1141:23-824)
320 330 340 350 360 370
pF1KA0 CASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIA
:: :: : : . . ...:. .:
XP_016 MVLSLTGLIAFSFLQATLALNPEDPNVCSHWESYAVTV--QESYAHPFDQIY
10 20 30 40 50
380 390 400 410 420
pF1KA0 VLQ-DELPQLFQDDDVGADEEEAELRGEHTLTEKFV-CLDDSF--GHDCSLTC-DDCRNG
. .. . :. . . : :: .:. .. : . : : : ..: .:
XP_016 YTRCTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHG
60 70 80 90 100 110
430 440 450 460 470 480
pF1KA0 GTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVS
:. . : : : :: : :. : : .: .:: :.::::. :. .:::: : :
XP_016 -RCV-SPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFR
120 130 140 150 160
490 500 510 520 530 540
pF1KA0 GTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGC
: ::. : : .:: :. :.: . . : : ::: :: : .:. ::: . : :
XP_016 GWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHC
170 180 190 200 210 220
550 560 570 580 590 600
pF1KA0 SEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSV
.: : . : : . : :.: :. : : : : :: .: : : : : :: :
XP_016 ELRCPCQNGGT--CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHV
230 240 250 260 270 280
610 620 630 640 650 660
pF1KA0 SGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDC
.:.: .: ::..:. : .::: :.:: .::. :.: .:. : .:: :.: :: : :
XP_016 TGQC--HCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRC
290 300 310 320 330 340
670 680 690 700 710 720
pF1KA0 -EADCPEGRWGLGCQEICPACQ--HAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSC
: :::: : :: :: :. .. : : :::: : ::. : .:.. ::.:.:: .:
XP_016 QERLCPEGLHGPGCTLPCP-CDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGC
350 360 370 380 390 400
730 740 750 760 770 780
pF1KA0 QTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAIS
: :.: : . :: :: :.::::. : : .: .: .::.:: :.:. : :.:. ..
XP_016 QLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNG-GTCSPVD
410 420 430 440 450 460
790 800 810 820 830 840
pF1KA0 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHA
: : :. :. : : ::.: .: .:.. : : .::::. ..:.:.: :: : ::
XP_016 GSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELP
470 480 490 500 510 520
850 860 870 880 890 900
pF1KA0 CPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCL
:: : :::.: :.:. . .:: :.: : : :: : :: : : .: : .:
XP_016 CPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE
530 540 550 560 570 580
910 920 930 940 950
pF1KA0 NGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS-CPPAA-ACHHVTGACRCP
::: :.:. : : : :. : :: : :..:..::: : : .. :::..: :.:
XP_016 NGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECL
590 600 610 620 630 640
960 970 980 990 1000 1010
pF1KA0 PGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRF
:::.:. :.: : : .: : :::.: :.:.:. :.:.: :..: ::. .:: : .
XP_016 PGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFW
650 660 670 680 690 700
1020 1030 1040 1050 1060 1070
pF1KA0 GPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCH
:: : :.:.: .::.:. :.: : :: .:. : . :: :: : ..:.:.::. :
XP_016 GPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCD
710 720 730 740 750 760
1080 1090 1100 1110 1120 1130
pF1KA0 ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQAC
.:.:.: :.::.::: : :: .: .:. : : :::::. .:::: :.::: : :
XP_016 HISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRC
770 780 790 800 810 820
1140 1150 1160 1170 1180 1190
pF1KA0 EHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRL
..
XP_016 DQAALMMEELNPYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRD
830 840 850 860 870 880
>>NP_115821 (OMIM: 612454) multiple epidermal growth fac (1044 aa)
initn: 1996 init1: 1040 opt: 2348 Z-score: 1336.2 bits: 259.1 E(85289): 1.1e-67
Smith-Waterman score: 2650; 40.8% identity (60.5% similar) in 812 aa overlap (341-1141:23-824)
320 330 340 350 360 370
pF1KA0 CASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIA
:: :: : : . . ...:. .:
NP_115 MVLSLTGLIAFSFLQATLALNPEDPNVCSHWESYAVTV--QESYAHPFDQIY
10 20 30 40 50
380 390 400 410 420
pF1KA0 VLQ-DELPQLFQDDDVGADEEEAELRGEHTLTEKFV-CLDDSF--GHDCSLTC-DDCRNG
. .. . :. . . : :: .:. .. : . : : : ..: .:
NP_115 YTRCTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHG
60 70 80 90 100 110
430 440 450 460 470 480
pF1KA0 GTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVS
:. . : : : :: : :. : : .: .:: :.::::. :. .:::: : :
NP_115 -RCV-SPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFR
120 130 140 150 160
490 500 510 520 530 540
pF1KA0 GTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGC
: ::. : : .:: :. :.: . . : : ::: :: : .:. ::: . : :
NP_115 GWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHC
170 180 190 200 210 220
550 560 570 580 590 600
pF1KA0 SEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSV
.: : . : : . : :.: :. : : : : :: .: : : : : :: :
NP_115 ELRCPCQNGGT--CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHV
230 240 250 260 270 280
610 620 630 640 650 660
pF1KA0 SGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDC
.:.: .: ::..:. : .::: :.:: .::. :.: .:. : .:: :.: :: : :
NP_115 TGQC--HCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRC
290 300 310 320 330 340
670 680 690 700 710 720
pF1KA0 -EADCPEGRWGLGCQEICPACQ--HAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSC
: :::: : :: :: :. .. : : :::: : ::. : .:.. ::.:.:: .:
NP_115 QERLCPEGLHGPGCTLPCP-CDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGC
350 360 370 380 390 400
730 740 750 760 770 780
pF1KA0 QTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAIS
: :.: : . :: :: :.::::. : : .: .: .::.:: :.:. : :.:. ..
NP_115 QLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNG-GTCSPVD
410 420 430 440 450 460
790 800 810 820 830 840
pF1KA0 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHA
: : :. :. : : ::.: .: .:.. : : .::::. ..:.:.: :: : ::
NP_115 GSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELP
470 480 490 500 510 520
850 860 870 880 890 900
pF1KA0 CPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCL
:: : :::.: :.:. . .:: :.: : : :: : :: : : .: : .:
NP_115 CPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE
530 540 550 560 570 580
910 920 930 940 950
pF1KA0 NGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS-CPPAA-ACHHVTGACRCP
::: :.:. : : : :. : :: : :..:..::: : : .. :::..: :.:
NP_115 NGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECL
590 600 610 620 630 640
960 970 980 990 1000 1010
pF1KA0 PGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRF
:::.:. :.: : : .: : :::.: :.:.:. :.:.: :..: ::. .:: : .
NP_115 PGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFW
650 660 670 680 690 700
1020 1030 1040 1050 1060 1070
pF1KA0 GPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCH
:: : :.:.: .::.:. :.: : :: .:. : . :: :: : ..:.:.::. :
NP_115 GPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCD
710 720 730 740 750 760
1080 1090 1100 1110 1120 1130
pF1KA0 ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQAC
.:.:.: :.::.::: : :: .: .:. : : :::::. .:::: :.::: : :
NP_115 HISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRC
770 780 790 800 810 820
1140 1150 1160 1170 1180 1190
pF1KA0 EHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRL
..
NP_115 DQAALMMEELNPYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRD
830 840 850 860 870 880
>>XP_016878161 (OMIM: 612454) PREDICTED: multiple epider (1044 aa)
initn: 1996 init1: 1040 opt: 2348 Z-score: 1336.2 bits: 259.1 E(85289): 1.1e-67
Smith-Waterman score: 2650; 40.8% identity (60.5% similar) in 812 aa overlap (341-1141:23-824)
320 330 340 350 360 370
pF1KA0 CASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIA
:: :: : : . . ...:. .:
XP_016 MVLSLTGLIAFSFLQATLALNPEDPNVCSHWESYAVTV--QESYAHPFDQIY
10 20 30 40 50
380 390 400 410 420
pF1KA0 VLQ-DELPQLFQDDDVGADEEEAELRGEHTLTEKFV-CLDDSF--GHDCSLTC-DDCRNG
. .. . :. . . : :: .:. .. : . : : : ..: .:
XP_016 YTRCTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHG
60 70 80 90 100 110
430 440 450 460 470 480
pF1KA0 GTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVS
:. . : : : :: : :. : : .: .:: :.::::. :. .:::: : :
XP_016 -RCV-SPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFR
120 130 140 150 160
490 500 510 520 530 540
pF1KA0 GTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGC
: ::. : : .:: :. :.: . . : : ::: :: : .:. ::: . : :
XP_016 GWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHC
170 180 190 200 210 220
550 560 570 580 590 600
pF1KA0 SEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSV
.: : . : : . : :.: :. : : : : :: .: : : : : :: :
XP_016 ELRCPCQNGGT--CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHV
230 240 250 260 270 280
610 620 630 640 650 660
pF1KA0 SGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDC
.:.: .: ::..:. : .::: :.:: .::. :.: .:. : .:: :.: :: : :
XP_016 TGQC--HCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRC
290 300 310 320 330 340
670 680 690 700 710 720
pF1KA0 -EADCPEGRWGLGCQEICPACQ--HAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSC
: :::: : :: :: :. .. : : :::: : ::. : .:.. ::.:.:: .:
XP_016 QERLCPEGLHGPGCTLPCP-CDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGC
350 360 370 380 390 400
730 740 750 760 770 780
pF1KA0 QTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAIS
: :.: : . :: :: :.::::. : : .: .: .::.:: :.:. : :.:. ..
XP_016 QLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNG-GTCSPVD
410 420 430 440 450 460
790 800 810 820 830 840
pF1KA0 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHA
: : :. :. : : ::.: .: .:.. : : .::::. ..:.:.: :: : ::
XP_016 GSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELP
470 480 490 500 510 520
850 860 870 880 890 900
pF1KA0 CPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCL
:: : :::.: :.:. . .:: :.: : : :: : :: : : .: : .:
XP_016 CPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE
530 540 550 560 570 580
910 920 930 940 950
pF1KA0 NGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS-CPPAA-ACHHVTGACRCP
::: :.:. : : : :. : :: : :..:..::: : : .. :::..: :.:
XP_016 NGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECL
590 600 610 620 630 640
960 970 980 990 1000 1010
pF1KA0 PGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRF
:::.:. :.: : : .: : :::.: :.:.:. :.:.: :..: ::. .:: : .
XP_016 PGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFW
650 660 670 680 690 700
1020 1030 1040 1050 1060 1070
pF1KA0 GPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCH
:: : :.:.: .::.:. :.: : :: .:. : . :: :: : ..:.:.::. :
XP_016 GPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCD
710 720 730 740 750 760
1080 1090 1100 1110 1120 1130
pF1KA0 ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQAC
.:.:.: :.::.::: : :: .: .:. : : :::::. .:::: :.::: : :
XP_016 HISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRC
770 780 790 800 810 820
1140 1150 1160 1170 1180 1190
pF1KA0 EHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRL
..
XP_016 DQAALMMEELNPYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRD
830 840 850 860 870 880
1229 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:21:20 2016 done: Thu Nov 3 10:21:22 2016
Total Scan time: 13.340 Total Display time: 0.560
Function used was FASTA [36.3.4 Apr, 2011]