FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0834, 451 aa 1>>>pF1KA0834 451 - 451 aa - 451 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.7423+/-0.000585; mu= -20.6150+/- 0.035 mean_var=676.9389+/-148.156, 0's: 0 Z-trim(115.7): 1521 B-trim: 0 in 0/53 Lambda= 0.049295 statistics sampled from 24231 (26420) to 24231 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.31), width: 16 Scan time: 9.020 The best scores are: opt bits E(85289) NP_036527 (OMIM: 610679) cyclin-dependent kinase 1 ( 451) 3031 231.6 3.2e-60 NP_001274064 (OMIM: 610679) cyclin-dependent kinas ( 469) 2864 219.8 1.2e-56 XP_011514608 (OMIM: 610679) PREDICTED: cyclin-depe ( 469) 2864 219.8 1.2e-56 XP_005250493 (OMIM: 610679) PREDICTED: cyclin-depe ( 450) 2862 219.6 1.3e-56 XP_005250495 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 2828 217.2 6.9e-56 XP_016867810 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 2828 217.2 6.9e-56 NP_001274065 (OMIM: 610679) cyclin-dependent kinas ( 423) 2828 217.2 6.9e-56 XP_016867811 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 2828 217.2 6.9e-56 XP_016867809 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 2828 217.2 6.9e-56 XP_005250496 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 2828 217.2 6.9e-56 NP_001274066 (OMIM: 610679) cyclin-dependent kinas ( 340) 2111 166.1 1.3e-40 XP_011514609 (OMIM: 610679) PREDICTED: cyclin-depe ( 285) 1549 126.0 1.3e-28 NP_631897 (OMIM: 616147) cyclin-dependent kinase 1 ( 384) 1535 125.2 3.1e-28 XP_005246839 (OMIM: 616147) PREDICTED: cyclin-depe ( 384) 1535 125.2 3.1e-28 XP_005246838 (OMIM: 616147) PREDICTED: cyclin-depe ( 435) 1535 125.2 3.4e-28 NP_001248364 (OMIM: 616147) cyclin-dependent kinas ( 429) 1498 122.6 2.1e-27 XP_011509952 (OMIM: 616147) PREDICTED: cyclin-depe ( 412) 1476 121.0 5.9e-27 NP_001248365 (OMIM: 616147) cyclin-dependent kinas ( 400) 1473 120.8 6.8e-27 XP_011509954 (OMIM: 616147) PREDICTED: cyclin-depe ( 372) 1281 107.1 8.3e-23 XP_011509956 (OMIM: 616147) PREDICTED: cyclin-depe ( 344) 1268 106.1 1.5e-22 NP_006192 (OMIM: 311550) cyclin-dependent kinase 1 ( 496) 1237 104.1 8.7e-22 XP_016885060 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1237 104.1 8.7e-22 XP_016885062 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1237 104.1 8.7e-22 XP_016885061 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1237 104.1 8.7e-22 XP_016885059 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1237 104.1 8.7e-22 XP_011542230 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1237 104.1 8.7e-22 XP_011542229 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1237 104.1 8.7e-22 XP_011542228 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1237 104.1 8.7e-22 XP_011542227 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1237 104.1 8.7e-22 XP_011542226 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1237 104.1 8.7e-22 NP_148978 (OMIM: 311550) cyclin-dependent kinase 1 ( 502) 1237 104.1 8.8e-22 XP_011542225 (OMIM: 311550) PREDICTED: cyclin-depe ( 503) 1237 104.1 8.8e-22 XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1237 104.1 9e-22 NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 1237 104.1 9e-22 XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1237 104.1 9e-22 XP_011542224 (OMIM: 311550) PREDICTED: cyclin-depe ( 540) 1237 104.2 9.2e-22 XP_016885058 (OMIM: 311550) PREDICTED: cyclin-depe ( 543) 1237 104.2 9.2e-22 XP_011542223 (OMIM: 311550) PREDICTED: cyclin-depe ( 544) 1237 104.2 9.2e-22 NP_001163931 (OMIM: 311550) cyclin-dependent kinas ( 570) 1237 104.2 9.5e-22 XP_011542222 (OMIM: 311550) PREDICTED: cyclin-depe ( 571) 1237 104.2 9.5e-22 NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 1234 103.9 1e-21 NP_002587 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1227 103.4 1.4e-21 NP_997667 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1227 103.4 1.4e-21 NP_997668 (OMIM: 169190) cyclin-dependent kinase 1 ( 504) 1227 103.4 1.4e-21 XP_011507904 (OMIM: 169190) PREDICTED: cyclin-depe ( 542) 1227 103.4 1.5e-21 XP_016856912 (OMIM: 169190) PREDICTED: cyclin-depe ( 572) 1227 103.5 1.6e-21 XP_011509957 (OMIM: 616147) PREDICTED: cyclin-depe ( 255) 1097 93.8 5.7e-19 XP_011509958 (OMIM: 616147) PREDICTED: cyclin-depe ( 255) 1097 93.8 5.7e-19 NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 1037 89.6 1.2e-17 NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 1003 87.2 6.6e-17 >>NP_036527 (OMIM: 610679) cyclin-dependent kinase 14 is (451 aa) initn: 3031 init1: 3031 opt: 3031 Z-score: 1202.1 bits: 231.6 E(85289): 3.2e-60 Smith-Waterman score: 3031; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV 370 380 390 400 410 420 430 440 450 pF1KA0 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH ::::::::::::::::::::::::::::::: NP_036 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH 430 440 450 >>NP_001274064 (OMIM: 610679) cyclin-dependent kinase 14 (469 aa) initn: 2864 init1: 2864 opt: 2864 Z-score: 1137.7 bits: 219.8 E(85289): 1.2e-56 Smith-Waterman score: 2864; 99.8% identity (100.0% similar) in 429 aa overlap (23-451:41-469) 10 20 30 40 50 pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKK .::::::::::::::::::::::::::::: NP_001 EKIGKMKKLRRTLSESFSRIALKKDDTTFDEICVTKMSTRNCQGMDSVIKPLDTIPEDKK 20 30 40 50 60 70 60 70 80 90 100 110 pF1KA0 VRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFG 80 90 100 110 120 130 120 130 140 150 160 170 pF1KA0 KADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKH 140 150 160 170 180 190 180 190 200 210 220 230 pF1KA0 ANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQR 200 210 220 230 240 250 240 250 260 270 280 290 pF1KA0 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYS 260 270 280 290 300 310 300 310 320 330 340 350 pF1KA0 TCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER 320 330 340 350 360 370 360 370 380 390 400 410 pF1KA0 FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELT 380 390 400 410 420 430 420 430 440 450 pF1KA0 DMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH ::::::::::::::::::::::::::::::::::::::: NP_001 DMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH 440 450 460 >>XP_011514608 (OMIM: 610679) PREDICTED: cyclin-dependen (469 aa) initn: 2864 init1: 2864 opt: 2864 Z-score: 1137.7 bits: 219.8 E(85289): 1.2e-56 Smith-Waterman score: 2864; 99.8% identity (100.0% similar) in 429 aa overlap (23-451:41-469) 10 20 30 40 50 pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKK .::::::::::::::::::::::::::::: XP_011 EKIGKMKKLRRTLSESFSRIALKKDDTTFDEICVTKMSTRNCQGMDSVIKPLDTIPEDKK 20 30 40 50 60 70 60 70 80 90 100 110 pF1KA0 VRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFG 80 90 100 110 120 130 120 130 140 150 160 170 pF1KA0 KADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKH 140 150 160 170 180 190 180 190 200 210 220 230 pF1KA0 ANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQR 200 210 220 230 240 250 240 250 260 270 280 290 pF1KA0 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYS 260 270 280 290 300 310 300 310 320 330 340 350 pF1KA0 TCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER 320 330 340 350 360 370 360 370 380 390 400 410 pF1KA0 FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELT 380 390 400 410 420 430 420 430 440 450 pF1KA0 DMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH ::::::::::::::::::::::::::::::::::::::: XP_011 DMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH 440 450 460 >>XP_005250493 (OMIM: 610679) PREDICTED: cyclin-dependen (450 aa) initn: 2862 init1: 2862 opt: 2862 Z-score: 1137.1 bits: 219.6 E(85289): 1.3e-56 Smith-Waterman score: 2862; 100.0% identity (100.0% similar) in 428 aa overlap (24-451:23-450) 10 20 30 40 50 60 pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS ::::::::::::::::::::::::::::::::::::: XP_005 MTPPLMSFDDCQNKVLALPGSLICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV 360 370 380 390 400 410 430 440 450 pF1KA0 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH ::::::::::::::::::::::::::::::: XP_005 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH 420 430 440 450 >>XP_005250495 (OMIM: 610679) PREDICTED: cyclin-dependen (423 aa) initn: 2828 init1: 2828 opt: 2828 Z-score: 1124.4 bits: 217.2 E(85289): 6.9e-56 Smith-Waterman score: 2828; 100.0% identity (100.0% similar) in 423 aa overlap (29-451:1-423) 10 20 30 40 50 60 pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS :::::::::::::::::::::::::::::::: XP_005 MSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS 10 20 30 70 80 90 100 110 120 pF1KA0 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA0 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA0 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA0 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA0 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA0 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV 340 350 360 370 380 390 430 440 450 pF1KA0 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH ::::::::::::::::::::::::::::::: XP_005 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH 400 410 420 >>XP_016867810 (OMIM: 610679) PREDICTED: cyclin-dependen (423 aa) initn: 2828 init1: 2828 opt: 2828 Z-score: 1124.4 bits: 217.2 E(85289): 6.9e-56 Smith-Waterman score: 2828; 100.0% identity (100.0% similar) in 423 aa overlap (29-451:1-423) 10 20 30 40 50 60 pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS :::::::::::::::::::::::::::::::: XP_016 MSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS 10 20 30 70 80 90 100 110 120 pF1KA0 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA0 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA0 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA0 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA0 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA0 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV 340 350 360 370 380 390 430 440 450 pF1KA0 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH ::::::::::::::::::::::::::::::: XP_016 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH 400 410 420 >>NP_001274065 (OMIM: 610679) cyclin-dependent kinase 14 (423 aa) initn: 2828 init1: 2828 opt: 2828 Z-score: 1124.4 bits: 217.2 E(85289): 6.9e-56 Smith-Waterman score: 2828; 100.0% identity (100.0% similar) in 423 aa overlap (29-451:1-423) 10 20 30 40 50 60 pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS :::::::::::::::::::::::::::::::: NP_001 MSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS 10 20 30 70 80 90 100 110 120 pF1KA0 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA0 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA0 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA0 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA0 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA0 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV 340 350 360 370 380 390 430 440 450 pF1KA0 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH ::::::::::::::::::::::::::::::: NP_001 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH 400 410 420 >>XP_016867811 (OMIM: 610679) PREDICTED: cyclin-dependen (423 aa) initn: 2828 init1: 2828 opt: 2828 Z-score: 1124.4 bits: 217.2 E(85289): 6.9e-56 Smith-Waterman score: 2828; 100.0% identity (100.0% similar) in 423 aa overlap (29-451:1-423) 10 20 30 40 50 60 pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS :::::::::::::::::::::::::::::::: XP_016 MSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS 10 20 30 70 80 90 100 110 120 pF1KA0 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA0 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA0 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA0 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA0 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA0 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV 340 350 360 370 380 390 430 440 450 pF1KA0 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH ::::::::::::::::::::::::::::::: XP_016 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH 400 410 420 >>XP_016867809 (OMIM: 610679) PREDICTED: cyclin-dependen (423 aa) initn: 2828 init1: 2828 opt: 2828 Z-score: 1124.4 bits: 217.2 E(85289): 6.9e-56 Smith-Waterman score: 2828; 100.0% identity (100.0% similar) in 423 aa overlap (29-451:1-423) 10 20 30 40 50 60 pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS :::::::::::::::::::::::::::::::: XP_016 MSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS 10 20 30 70 80 90 100 110 120 pF1KA0 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA0 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA0 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA0 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA0 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA0 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV 340 350 360 370 380 390 430 440 450 pF1KA0 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH ::::::::::::::::::::::::::::::: XP_016 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH 400 410 420 >>XP_005250496 (OMIM: 610679) PREDICTED: cyclin-dependen (423 aa) initn: 2828 init1: 2828 opt: 2828 Z-score: 1124.4 bits: 217.2 E(85289): 6.9e-56 Smith-Waterman score: 2828; 100.0% identity (100.0% similar) in 423 aa overlap (29-451:1-423) 10 20 30 40 50 60 pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS :::::::::::::::::::::::::::::::: XP_005 MSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS 10 20 30 70 80 90 100 110 120 pF1KA0 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA0 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA0 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA0 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA0 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA0 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV 340 350 360 370 380 390 430 440 450 pF1KA0 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH ::::::::::::::::::::::::::::::: XP_005 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH 400 410 420 451 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:49:39 2016 done: Wed Nov 2 19:49:40 2016 Total Scan time: 9.020 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]