FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0840, 491 aa 1>>>pF1KA0840 491 - 491 aa - 491 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1246+/-0.000376; mu= 9.9538+/- 0.024 mean_var=128.1072+/-26.033, 0's: 0 Z-trim(116.2): 127 B-trim: 0 in 0/54 Lambda= 0.113315 statistics sampled from 27104 (27250) to 27104 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.32), width: 16 Scan time: 7.470 The best scores are: opt bits E(85289) NP_036436 (OMIM: 605656) F-box/LRR-repeat protein ( 491) 3321 554.4 2.6e-157 XP_016864751 (OMIM: 605656) PREDICTED: F-box/LRR-r ( 486) 3239 541.0 2.8e-153 NP_001265246 (OMIM: 605656) F-box/LRR-repeat prote ( 444) 3028 506.5 6.3e-143 XP_011512300 (OMIM: 605656) PREDICTED: F-box/LRR-r ( 444) 3028 506.5 6.3e-143 NP_036289 (OMIM: 605652) F-box/LRR-repeat protein ( 423) 527 97.6 7.2e-20 NP_116264 (OMIM: 609086) F-box/LRR-repeat protein ( 436) 520 96.5 1.6e-19 XP_005257803 (OMIM: 609086) PREDICTED: F-box/LRR-r ( 473) 520 96.5 1.8e-19 XP_005265071 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 454) 469 88.2 5.5e-17 XP_016861583 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 318) 434 82.3 2.2e-15 XP_005265074 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 318) 434 82.3 2.2e-15 NP_001171835 (OMIM: 609086) F-box/LRR-repeat prote ( 404) 421 80.3 1.1e-14 XP_005257804 (OMIM: 609086) PREDICTED: F-box/LRR-r ( 441) 421 80.3 1.2e-14 XP_016861582 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349) 376 72.9 1.7e-12 XP_011531861 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349) 376 72.9 1.7e-12 XP_005265072 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349) 376 72.9 1.7e-12 XP_016861581 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349) 376 72.9 1.7e-12 XP_005265073 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349) 376 72.9 1.7e-12 XP_011514234 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 639) 348 68.5 6.5e-11 NP_001104508 (OMIM: 609080) F-box/LRR-repeat prote ( 690) 348 68.5 6.9e-11 XP_005250265 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 780) 348 68.5 7.6e-11 NP_001165184 (OMIM: 605652) F-box/LRR-repeat prote ( 355) 330 65.4 3.1e-10 XP_006715961 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 584) 332 65.8 3.7e-10 XP_016867342 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 735) 332 65.9 4.5e-10 XP_005250266 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 735) 332 65.9 4.5e-10 NP_659469 (OMIM: 609080) F-box/LRR-repeat protein ( 735) 332 65.9 4.5e-10 XP_011514232 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 735) 332 65.9 4.5e-10 XP_016867341 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 780) 332 65.9 4.7e-10 XP_005250264 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 792) 332 65.9 4.7e-10 XP_016867339 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 822) 332 65.9 4.9e-10 XP_005250262 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 825) 332 65.9 4.9e-10 NP_001274079 (OMIM: 609080) F-box/LRR-repeat prote ( 707) 328 65.2 6.8e-10 XP_011514230 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 797) 328 65.3 7.5e-10 XP_016867340 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 809) 328 65.3 7.6e-10 XP_011514231 (OMIM: 609080) PREDICTED: F-box/LRR-r ( 783) 323 64.4 1.3e-09 XP_016866217 (OMIM: 605654,615471) PREDICTED: F-bo ( 379) 315 62.9 1.8e-09 XP_016866215 (OMIM: 605654,615471) PREDICTED: F-bo ( 621) 315 63.1 2.7e-09 NP_036292 (OMIM: 605654,615471) F-box/LRR-repeat p ( 621) 315 63.1 2.7e-09 NP_001265645 (OMIM: 605654,615471) F-box/LRR-repea ( 621) 315 63.1 2.7e-09 XP_016865218 (OMIM: 609083) PREDICTED: F-box/LRR-r ( 567) 304 61.3 8.7e-09 XP_011541880 (OMIM: 609083) PREDICTED: F-box/LRR-r ( 582) 304 61.3 8.8e-09 XP_011541879 (OMIM: 609083) PREDICTED: F-box/LRR-r ( 589) 304 61.3 8.9e-09 XP_011541878 (OMIM: 609083) PREDICTED: F-box/LRR-r ( 610) 304 61.3 9.2e-09 XP_011541877 (OMIM: 609083) PREDICTED: F-box/LRR-r ( 618) 304 61.3 9.3e-09 XP_011541876 (OMIM: 609083) PREDICTED: F-box/LRR-r ( 621) 304 61.3 9.3e-09 NP_001156787 (OMIM: 609083) F-box/LRR-repeat prote ( 701) 304 61.3 1e-08 XP_005272105 (OMIM: 609083) PREDICTED: F-box/LRR-r ( 712) 304 61.3 1e-08 NP_078831 (OMIM: 609076) F-box/LRR-repeat protein ( 533) 293 59.4 2.9e-08 XP_005270207 (OMIM: 610287) PREDICTED: F-box/LRR-r ( 300) 287 58.3 3.6e-08 XP_005270208 (OMIM: 610287) PREDICTED: F-box/LRR-r ( 300) 287 58.3 3.6e-08 NP_077302 (OMIM: 610287) F-box/LRR-repeat protein ( 300) 287 58.3 3.6e-08 >>NP_036436 (OMIM: 605656) F-box/LRR-repeat protein 7 is (491 aa) initn: 3321 init1: 3321 opt: 3321 Z-score: 2945.2 bits: 554.4 E(85289): 2.6e-157 Smith-Waterman score: 3321; 100.0% identity (100.0% similar) in 491 aa overlap (1-491:1-491) 10 20 30 40 50 60 pF1KA0 MGANNGKQYGSEGKGSSSISSDVSSSTDHTPTKAQKNVATSEDSDLSMRTLSTPSPALIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MGANNGKQYGSEGKGSSSISSDVSSSTDHTPTKAQKNVATSEDSDLSMRTLSTPSPALIC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 PPNLPGFQNGRGSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PPNLPGFQNGRGSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 SMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 TPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 THLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 THLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 GRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 ECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKR 430 440 450 460 470 480 490 pF1KA0 CVIEHTNPAFF ::::::::::: NP_036 CVIEHTNPAFF 490 >>XP_016864751 (OMIM: 605656) PREDICTED: F-box/LRR-repea (486 aa) initn: 3239 init1: 3239 opt: 3239 Z-score: 2872.9 bits: 541.0 E(85289): 2.8e-153 Smith-Waterman score: 3239; 100.0% identity (100.0% similar) in 479 aa overlap (13-491:8-486) 10 20 30 40 50 60 pF1KA0 MGANNGKQYGSEGKGSSSISSDVSSSTDHTPTKAQKNVATSEDSDLSMRTLSTPSPALIC :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVYLSCPGKGSSSISSDVSSSTDHTPTKAQKNVATSEDSDLSMRTLSTPSPALIC 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 PPNLPGFQNGRGSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPNLPGFQNGRGSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDH 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 SMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 TPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 EHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 THLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHC 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 GRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGL 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA0 ECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKR 420 430 440 450 460 470 490 pF1KA0 CVIEHTNPAFF ::::::::::: XP_016 CVIEHTNPAFF 480 >>NP_001265246 (OMIM: 605656) F-box/LRR-repeat protein 7 (444 aa) initn: 3028 init1: 3028 opt: 3028 Z-score: 2687.0 bits: 506.5 E(85289): 6.3e-143 Smith-Waterman score: 3028; 100.0% identity (100.0% similar) in 444 aa overlap (48-491:1-444) 20 30 40 50 60 70 pF1KA0 SISSDVSSSTDHTPTKAQKNVATSEDSDLSMRTLSTPSPALICPPNLPGFQNGRGSSTSS :::::::::::::::::::::::::::::: NP_001 MRTLSTPSPALICPPNLPGFQNGRGSSTSS 10 20 30 80 90 100 110 120 130 pF1KA0 SSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRC 40 50 60 70 80 90 140 150 160 170 180 190 pF1KA0 ARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCR 100 110 120 130 140 150 200 210 220 230 240 250 pF1KA0 RLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLT 160 170 180 190 200 210 260 270 280 290 300 310 pF1KA0 REASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLR 220 230 240 250 260 270 320 330 340 350 360 370 pF1KA0 YLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSK 280 290 300 310 320 330 380 390 400 410 420 430 pF1KA0 LRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKS 340 350 360 370 380 390 440 450 460 470 480 490 pF1KA0 CESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF 400 410 420 430 440 >>XP_011512300 (OMIM: 605656) PREDICTED: F-box/LRR-repea (444 aa) initn: 3028 init1: 3028 opt: 3028 Z-score: 2687.0 bits: 506.5 E(85289): 6.3e-143 Smith-Waterman score: 3028; 100.0% identity (100.0% similar) in 444 aa overlap (48-491:1-444) 20 30 40 50 60 70 pF1KA0 SISSDVSSSTDHTPTKAQKNVATSEDSDLSMRTLSTPSPALICPPNLPGFQNGRGSSTSS :::::::::::::::::::::::::::::: XP_011 MRTLSTPSPALICPPNLPGFQNGRGSSTSS 10 20 30 80 90 100 110 120 130 pF1KA0 SSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRC 40 50 60 70 80 90 140 150 160 170 180 190 pF1KA0 ARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCR 100 110 120 130 140 150 200 210 220 230 240 250 pF1KA0 RLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLT 160 170 180 190 200 210 260 270 280 290 300 310 pF1KA0 REASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLR 220 230 240 250 260 270 320 330 340 350 360 370 pF1KA0 YLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSK 280 290 300 310 320 330 380 390 400 410 420 430 pF1KA0 LRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKS 340 350 360 370 380 390 440 450 460 470 480 490 pF1KA0 CESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF 400 410 420 430 440 >>NP_036289 (OMIM: 605652) F-box/LRR-repeat protein 2 is (423 aa) initn: 1129 init1: 335 opt: 527 Z-score: 477.6 bits: 97.6 E(85289): 7.2e-20 Smith-Waterman score: 644; 30.1% identity (65.9% similar) in 369 aa overlap (116-479:14-366) 90 100 110 120 130 140 pF1KA0 AMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWY .:: . ...::::: :::::.. . : NP_036 MVFSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWN 10 20 30 40 150 160 170 180 190 200 pF1KA0 NLAWDPRLWRTIRLTGETINVD-RALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGL :: : :. : : . .:. :... ...: : .:. ... :: . : .: NP_036 ILALDGSNWQRIDLFNFQTDVEGRVVENISKR-CGG------FLRKLSLRGCIGVGDSSL 50 60 70 80 90 210 220 230 240 250 260 pF1KA0 YTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKL :.:: : ....:...:: .:.. . ... .: .:.:::.. .:.:.: ..:.: NP_036 KTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLT-----SCVSIT-NSSLK- 100 110 120 130 140 270 280 290 300 310 320 pF1KA0 SPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCA . .: . ...::... : . .:..... : : : :: :..: ::.:... :: NP_036 GISEGCR-NLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCH 150 160 170 180 190 200 330 340 350 360 370 380 pF1KA0 SIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNAR . :....: ..: :. .: . ::. : .. :. .::... .. : .:. :.: NP_036 ELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAA 210 220 230 240 250 260 390 400 410 420 430 440 pF1KA0 GCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQ : .:: : ::.:: .:...:. .: :..:. : :...: .:. :::. :: :: . NP_036 RCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDD 270 280 290 300 310 320 450 460 470 480 490 pF1KA0 G-LQIVAANCFD--LQTLNVQDCEVSVE-ALRFVKRHCKRCVIEHTNPAFF : :.. ..: :..:....: . .. ::. .. .:. NP_036 GILHLSNSTCGHERLRVLELDNCLLITDVALEHLE-NCRGLERLELYDCQQVTRAGIKRM 330 340 350 360 370 380 NP_036 RAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCVIL 390 400 410 420 >>NP_116264 (OMIM: 609086) F-box/LRR-repeat protein 20 i (436 aa) initn: 807 init1: 330 opt: 520 Z-score: 471.3 bits: 96.5 E(85289): 1.6e-19 Smith-Waterman score: 628; 29.6% identity (63.1% similar) in 385 aa overlap (102-481:12-378) 80 90 100 110 120 130 pF1KA0 GSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDR-LPDHSMVQIFSFLP :. ....: :.. :: . ...::::: NP_116 MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLD 10 20 30 40 140 150 160 170 180 pF1KA0 TNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVD-RALKVLTRRLCQDTPNVCLMLE . :::::.: : : :: : :. : : ... :... ...: : .:. NP_116 VVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKR-CGG------FLR 50 60 70 80 90 190 200 210 220 230 240 pF1KA0 TVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCS ... :: . : .: :.:: : ... :...:: . .. . .. ..: .:.:::...:. NP_116 KLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCT 100 110 120 130 140 150 250 260 270 280 290 300 pF1KA0 KVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCV ..: .:: .: . :: .:..: . :. : .: :..... : : :.:. :. NP_116 SITNMSL--KALSEGCPLL-EQLNISWCDQ----VTKD-GIQALVRGCGGLKALFLKGCT 160 170 180 190 200 310 320 330 340 350 360 pF1KA0 RLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIR .: ::.:.:. .: . :... : ..: :: : . .:. : . :. .::. . NP_116 QLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILN 210 220 230 240 250 260 370 380 390 400 410 420 pF1KA0 YVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFN ... : .:: :.. : .:: : ::.:: .:...:. .: ..:. : :...: NP_116 ALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPR 270 280 290 300 310 320 430 440 450 460 470 480 pF1KA0 LKRLSLKSCESITGQGLQIVAAN-CF--DLQTLNVQDCEVSVEALRFVKRHCKRCVIEHT :. :::. :: :: .:.. .. . : .:.......: . ..: .: : : NP_116 LQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDA---SLEHLKSCHSLER 330 340 350 360 370 380 490 pF1KA0 NPAFF NP_116 IELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL 390 400 410 420 430 >>XP_005257803 (OMIM: 609086) PREDICTED: F-box/LRR-repea (473 aa) initn: 807 init1: 330 opt: 520 Z-score: 470.8 bits: 96.5 E(85289): 1.8e-19 Smith-Waterman score: 641; 28.7% identity (62.2% similar) in 397 aa overlap (90-481:37-415) 60 70 80 90 100 110 pF1KA0 CPPNLPGFQNGRGSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDR-LP .: :: : .. . ....: :.. :: XP_005 GGGGGGGGNRGGAAAAALPQSRHIQKRRKMAPSRDRLLHFGFKATMFSNSDEAVINKKLP 10 20 30 40 50 60 120 130 140 150 160 170 pF1KA0 DHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVD-RALKVLTRRL . ...::::: . :::::.: : : :: : :. : : ... :... ...: XP_005 KELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKR- 70 80 90 100 110 120 180 190 200 210 220 230 pF1KA0 CQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLC : .:. ... :: . : .: :.:: : ... :...:: . .. . .. ..: XP_005 CGG------FLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFC 130 140 150 160 170 240 250 260 270 280 290 pF1KA0 PNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHC .:.:::...:...: .:: .: . :: .. :... : . .:..... : XP_005 SKLRHLDLASCTSITNMSL--KALSEGCPL------LEQLNISWCDQVTKDGIQALVRGC 180 190 200 210 220 230 300 310 320 330 340 350 pF1KA0 TQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSI : :.:. :..: ::.:.:. .: . :... : ..: :: : . .:. : XP_005 GGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCA 240 250 260 270 280 290 360 370 380 390 400 410 pF1KA0 AHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSD . :. .::. . ... : .:: :.. : .:: : ::.:: .:...:. .: ..: XP_005 SGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITD 300 310 320 330 340 350 420 430 440 450 460 470 pF1KA0 TGLECLALNCFNLKRLSLKSCESITGQGLQIVAAN-CF--DLQTLNVQDCEVSVEALRFV . : :...: :. :::. :: :: .:.. .. . : .:.......: . ..: XP_005 STLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDA---S 360 370 380 390 400 480 490 pF1KA0 KRHCKRCVIEHTNPAFF .: : : XP_005 LEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCR 410 420 430 440 450 460 >>XP_005265071 (OMIM: 605652) PREDICTED: F-box/LRR-repea (454 aa) initn: 1108 init1: 270 opt: 469 Z-score: 426.0 bits: 88.2 E(85289): 5.5e-17 Smith-Waterman score: 586; 30.1% identity (65.2% similar) in 319 aa overlap (116-433:14-317) 90 100 110 120 130 140 pF1KA0 AMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWY .:: . ...::::: :::::.. . : XP_005 MVFSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWN 10 20 30 40 150 160 170 180 190 200 pF1KA0 NLAWDPRLWRTIRLTGETINVD-RALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGL :: : :. : : . .:. :... ...: : .:. ... :: . : .: XP_005 ILALDGSNWQRIDLFNFQTDVEGRVVENISKR-CGG------FLRKLSLRGCIGVGDSSL 50 60 70 80 90 210 220 230 240 250 260 pF1KA0 YTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKL :.:: : ....:...:: .:.. . ... .: .:.:::.. .:.:.: ..:.: XP_005 KTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLT-----SCVSIT-NSSLK- 100 110 120 130 140 270 280 290 300 310 320 pF1KA0 SPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCA . .: . ...::... : . .:..... : : : :: :..: ::.:... :: XP_005 GISEGCR-NLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCH 150 160 170 180 190 200 330 340 350 360 370 380 pF1KA0 SIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNAR . :....: ..: :. .: . ::. : .. :. .::... .. : .:. :.: XP_005 ELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAA 210 220 230 240 250 260 390 400 410 420 430 440 pF1KA0 GCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQ : .:: : ::.:: .:...:. .: :..:. : :...: .:. : XP_005 RCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALVSLSFSDIIHL 270 280 290 300 310 320 450 460 470 480 490 pF1KA0 GLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF XP_005 LKMKEPSHHNKKLFGFSFCKSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDV 330 340 350 360 370 380 >>XP_016861583 (OMIM: 605652) PREDICTED: F-box/LRR-repea (318 aa) initn: 590 init1: 335 opt: 434 Z-score: 397.3 bits: 82.3 E(85289): 2.2e-15 Smith-Waterman score: 457; 30.2% identity (62.2% similar) in 291 aa overlap (205-491:18-295) 180 190 200 210 220 230 pF1KA0 RRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVV :.... : .:..:....: .:.: .. . XP_016 MDAQKSLTVRLLFFSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGIS 10 20 30 40 240 250 260 270 280 290 pF1KA0 SLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIA : :::.:..: :...: .. :: .. : . ... : . : ::::.:. : XP_016 EGCRNLEYLNLSWCDQITKDGI--EALVR-----GCR-GLKALLLRGCTQLEDEALKHIQ 50 60 70 80 90 300 310 320 330 340 350 pF1KA0 AHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRY .: .:. : :. : :.::::. . : .. : .: : ..: .: .. ::. XP_016 NYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQI 100 110 120 130 140 150 360 370 380 390 400 410 pF1KA0 LSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPL : :.:...::.:. .:. : .:. .. . : ::: . :. .: ::..:....: : XP_016 LEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCEL 160 170 180 190 200 210 420 430 440 450 460 470 pF1KA0 VSDTGLECLALN-CFN--LKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEAL ..: :. :. . : . :. : : .: :: .:. . :: :. :.. ::. ..: XP_016 ITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLE-NCRGLERLELYDCQQVTRAG 220 230 240 250 260 270 480 490 pF1KA0 RFVKRHCKRCVIEHTN-PAFF .:: : . :.. :.: XP_016 --IKRM--RAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCVIL 280 290 300 310 >>XP_005265074 (OMIM: 605652) PREDICTED: F-box/LRR-repea (318 aa) initn: 590 init1: 335 opt: 434 Z-score: 397.3 bits: 82.3 E(85289): 2.2e-15 Smith-Waterman score: 457; 30.2% identity (62.2% similar) in 291 aa overlap (205-491:18-295) 180 190 200 210 220 230 pF1KA0 RRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVV :.... : .:..:....: .:.: .. . XP_005 MDAQKSLTVRLLFFSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGIS 10 20 30 40 240 250 260 270 280 290 pF1KA0 SLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIA : :::.:..: :...: .. :: .. : . ... : . : ::::.:. : XP_005 EGCRNLEYLNLSWCDQITKDGI--EALVR-----GCR-GLKALLLRGCTQLEDEALKHIQ 50 60 70 80 90 300 310 320 330 340 350 pF1KA0 AHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRY .: .:. : :. : :.::::. . : .. : .: : ..: .: .. ::. XP_005 NYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQI 100 110 120 130 140 150 360 370 380 390 400 410 pF1KA0 LSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPL : :.:...::.:. .:. : .:. .. . : ::: . :. .: ::..:....: : XP_005 LEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCEL 160 170 180 190 200 210 420 430 440 450 460 470 pF1KA0 VSDTGLECLALN-CFN--LKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEAL ..: :. :. . : . :. : : .: :: .:. . :: :. :.. ::. ..: XP_005 ITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLE-NCRGLERLELYDCQQVTRAG 220 230 240 250 260 270 480 490 pF1KA0 RFVKRHCKRCVIEHTN-PAFF .:: : . :.. :.: XP_005 --IKRM--RAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCVIL 280 290 300 310 491 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:04:03 2016 done: Fri Nov 4 01:04:04 2016 Total Scan time: 7.470 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]