Result of FASTA (ccds) for
pF1KA0847
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0847, 1244 aa
1>>>pF1KA0847 1244 - 1244 aa - 1244 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.5335+/-0.00115; mu= -4.3241+/- 0.069
mean_var=455.5870+/-98.781, 0's: 0 Z-trim(112.8): 128 B-trim: 0 in 0/54
Lambda= 0.060088
statistics sampled from 13392 (13485) to 13392 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.414), width: 16
Scan time: 5.540
The best scores are: opt bits E(32554)
CCDS42029.1 TTBK2 gene_id:146057|Hs108|chr15 (1244) 8289 734.5 4e-211
CCDS34455.1 TTBK1 gene_id:84630|Hs108|chr6 (1321) 2119 199.6 4.3e-50
>>CCDS42029.1 TTBK2 gene_id:146057|Hs108|chr15 (1244 aa)
initn: 8289 init1: 8289 opt: 8289 Z-score: 3903.8 bits: 734.5 E(32554): 4e-211
Smith-Waterman score: 8289; 99.9% identity (99.9% similar) in 1244 aa overlap (1-1244:1-1244)
10 20 30 40 50 60
pF1KA0 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQV
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 RAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 RAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 RYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 RYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 GNDGSLTTTTTSTTPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GNDGSLTTTTTSTTPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VGVSPDKLPGSLGHPRPQEKDVWEEMDANKNKIKLGICKAATEEENSHGQANGLLNAPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 VGVSPDKLPGSLGHPRPQEKDVWEEMDANKNKIKLGICKAATEEENSHGQANGLLNAPSL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTDKFLETCLEKMQKDTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTDKFLETCLEKMQKDTSA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 GKESILPALLHKPCVPAVSRTDHIWHYDEEYLPDASKPASANTPEQADGGGSNGFIAVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GKESILPALLHKPCVPAVSRTDHIWHYDEEYLPDASKPASANTPEQADGGGSNGFIAVNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPSDEEPEVLQVLEASPQDEKLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPSDEEPEVLQVLEASPQDEKLQL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GPWAENDHLKKETSGVVLALSAEGPPTAASEQYTDRLELQPGAASQFIAATPTSLMEAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GPWAENDHLKKETSGVVLALSAEGPPTAASEQYTDRLELQPGAASQFIAATPTSLMEAQA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EGPLTAITIPRPSVASTQSTSGSFHCGQQPEKKDLQPMEPTVELYSPRENFSGLVVTEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EGPLTAITIPRPSVASTQSTSGSFHCGQQPEKKDLQPMEPTVELYSPRENFSGLVVTEGE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PPSGGSRTDLGLQIDHIGHDMLPNIRESNKSQDLGPKELPDHNRLVVREFENLPGETEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PPSGGSRTDLGLQIDHIGHDMLPNIRESNKSQDLGPKELPDHNRLVVREFENLPGETEEK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 SILLESDNEDEKLSRGQHCIEISSLPGDLVIVEKDHSATTEPLDVTKTQTFSVVPNQDKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SILLESDNEDEKLSRGQHCIEISSLPGDLVIVEKDHSATTEPLDVTKTQTFSVVPNQDKN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 NEIMKLLTVGTSEISSRDIDPHVEGQIGQVAEMQKNKISKDDDIMSEDLPGHQGDLSTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 NEIMKLLTVGTSEISSRDIDPHVEGQIGQVAEMQKNKISKDDDIMSEDLPGHQGDLSTFL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 HQEGKREKITPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEIDSTLESSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 HQEGKREKITPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEIDSTLESSS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 PVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPAPFCEEEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPAPFCEEEVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 TPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQFFPRPPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQFFPRPPPG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGSQKPRSTTQCKSPGSPHNPKTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGSQKPRSTTQCKSPGSPHNPKTP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 PKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPHHDQRSSSPHLGRSKSPPSHSGSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPHHDQRSSSPHLGRSKSPPSHSGSSSS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240
pF1KA0 RRSCQQEHCKPSKNGLKGSGSLHHHSASTKTPQGKSKPASKLSR
::::::::::::::::::::::::::::::::::::::::::::
CCDS42 RRSCQQEHCKPSKNGLKGSGSLHHHSASTKTPQGKSKPASKLSR
1210 1220 1230 1240
>>CCDS34455.1 TTBK1 gene_id:84630|Hs108|chr6 (1321 aa)
initn: 2390 init1: 1809 opt: 2119 Z-score: 1012.8 bits: 199.6 E(32554): 4.3e-50
Smith-Waterman score: 2364; 39.6% identity (60.0% similar) in 1336 aa overlap (1-1193:14-1288)
10 20 30 40
pF1KA0 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENV
::::::: ::: .. .::.:::::.:::::::::::.:.:.::::::
CCDS34 MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 ALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRS
:::::::::::::::::::::::::::::::::::::::..:::::::::::::::::::
CCDS34 ALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 QSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLA
: :::::.:::::::.:::::::.::::::::::::::::::::.::: :::::::::::
CCDS34 QPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 RQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWR
::.::. ::::::: ::::::::::::.:::.::::::::::::::::::::.:::::::
CCDS34 RQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWR
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 KIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTF
::::::::: :::.:.::..:::.: :: .:::::.::::::::::::. :::.::.:
CCDS34 KIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKER
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 GVIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIGIANATPIPGDLLRENTDEVF
:. :.. :::::.:.: .: .:.::: :: .:: : : .:..:.::.:::::::::..:.
CCDS34 GIAENEAFDWEKAGTD-ALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVL
310 320 330 340 350
350 360 370 380 390 400
pF1KA0 PDEQLSDGENGIPV-------GVSPDKLPGSLGHPRPQEKDVWEEMDANKNKIKLGICKA
:.::: ::. :. :..:. : . :: : .:::: :.:.::....: :.
CCDS34 QGEHLSDQENAPPILPGRPSEGLGPS--PHLVPHPGGPEAEVWEETDVNRNKLRINIGKS
360 370 380 390 400 410
410 420 430 440 450
pF1KA0 A-TEEENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLR--SIHSFELEKRLTL
.:::.:.: ...:: ::.:. :: ::.:: ..: : : ::.
CCDS34 PCVEEEQSRG-----MGVPS--SPVRA-----PPDSPTTPVRSLRYRRVNSPESE-RLST
420 430 440 450 460
460 470 480 490 500 510
pF1KA0 EPKPDTDKFLETCLEKMQKDTSAGKESILPALLHKPCV--PAVSRTDHIWHYDEEYLPDA
.: .: .. . : :. : .. : :: . : :.. ..
CCDS34 -----ADGRVELPERRSRMDLP-GSPS------RQACSSQPAQMLSVDTGHADRQ--ASG
470 480 490 500 510
520 530 540 550 560 570
pF1KA0 SKPASANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTT
.::.. ..: ::.: .: :. ....:::::::.::: .:.:: . .. .:
CCDS34 RMDVSASVEQEA---LSNAFRSVPLAE-EEDFDSKEWVIIDKETELKDFPPG---AEPST
520 530 540 550 560
580 590 600 610 620
pF1KA0 GSPSDEEPEVLQVL-EASPQDEKLQLGP-----------WAEND--HLKKETSGVVLALS
.. .::::: :. : : . . ..: : ::.: :: . :. .
CCDS34 SGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDLQHLPPQPLPPQLS-Q
570 580 590 600 610 620
630 640 650 660
pF1KA0 AEG------PPTAASEQYTD--------RLELQP-GAASQ-FIAATPTSLMEAQAEGPLT
..: ::: .: ... : : .: : : : .: : . ::.
CCDS34 GDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLS
630 640 650 660 670 680
670 680 690
pF1KA0 A-------------------------------ITIPRPSVASTQSTSGSFHCGQQPEKKD
.: :. .: .: ... . .. :. .
CCDS34 LPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDE
690 700 710 720 730 740
700 710 720 730 740 750
pF1KA0 LQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQID-HIGHDMLPNIRESNKSQD
. : : .:. : : ... . :: . . : . . : ...::.
CCDS34 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQE
750 760 770 780 790 800
760 770 780 790 800
pF1KA0 LGPKELPDHNRLVVREFENLPG---ETEE--KSILLESDNEDEKLSRGQHCIEISSLP--
.:. : .. : .. : :: :...: : .. .... :.. :
CCDS34 GAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGD---MKKSPVTAELAPDPDL
810 820 830 840 850
810 820 830 840 850
pF1KA0 GDLVIVEKDH---SATTEPLDVTKTQTFS-VVPNQDKNNEIMKLLTVGTSEISSRDI---
: :. . .: . : :::.. :.: :. .. : : .:: . .
CCDS34 GTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGAGTVTTGVGGVAVT
860 870 880 890 900 910
860 870 880 890 900 910
pF1KA0 -DP--HVEGQIGQVAEMQK-NKISKDDDIMSEDLPGHQGDLSTFLHQEGKREKITPR---
.: .:: . ..:: . : .:. . . . . :.:. : ..: . :
CCDS34 SSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGELGLELASDGGAVEEGARAPL
920 930 940 950 960 970
920 930 940
pF1KA0 -NGELFHCVSENE------HGAP--TRKDMVRSSFVT-----------------------
:: . .. : ::: : ..:. .:. .
CCDS34 ENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPALADGPAPVSPLEPSPEKVAT
980 990 1000 1010 1020 1030
950 960 970 980
pF1KA0 ----RH--------SRIPVLAQEIDSTLESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQF
:: :::::: .: :. : :. .::::. .. : ::..:..::::
CCDS34 ISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQG
1040 1050 1060 1070 1080 1090
990 1000 1010 1020 1030 1040
pF1KA0 KSFLGDLSSASDKLLEEKL---ATVPAPFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPII
. .: :.::.. ::. :. . ::. :: :. . . : :.. .
CCDS34 RLLLRLASGASSSSSEEQRRASETLSGTGSEED--TPASEPA--AALPRKSGRA------
1100 1110 1120 1130 1140
1050 1060 1070 1080 1090 1100
pF1KA0 SQSRKSKIPRPVSWVNTDQVNSSTSSQFFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDS
. .:.::::.. : ...: : . : .. .::. ::... .
CCDS34 -AATRSRIPRPIGLRMPMPV---AAQQPASRSHGAAPALDTAITSRLQLQTPPGSATA-A
1150 1160 1170 1180 1190 1200
1110 1120 1130 1140 1150 1160
pF1KA0 DLFSRLAQILQNGSQKPRSTTQCKSPGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSS
:: : : : :. . . : .:..:. : .. .. :. ::::::.:: : :
CCDS34 DL--RPKQPPGRGLGPGRAQAGARPP-APRSPRLPASTSAA--RNASASPRSQSLSRRES
1210 1220 1230 1240 1250
1170 1180 1190 1200 1210 1220
pF1KA0 SSPSRAGRPH-HDQRSSSPHLGRSKSPPSHSGSSSSRRSCQQEHCKPSKNGLKGSGSLHH
:::. .:: :. : .. . ::
CCDS34 PSPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAG
1260 1270 1280 1290 1300 1310
1244 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:49:56 2016 done: Thu Nov 3 19:49:57 2016
Total Scan time: 5.540 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]