FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0850, 642 aa 1>>>pF1KA0850 642 - 642 aa - 642 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7913+/-0.000409; mu= 17.0192+/- 0.025 mean_var=98.1520+/-21.521, 0's: 0 Z-trim(111.9): 327 B-trim: 1019 in 1/54 Lambda= 0.129457 statistics sampled from 20254 (20670) to 20254 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.242), width: 16 Scan time: 8.920 The best scores are: opt bits E(85289) NP_006460 (OMIM: 609209) influenza virus NS1A-bind ( 642) 4391 831.5 0 XP_011507381 (OMIM: 609209) PREDICTED: influenza v ( 649) 4367 827.0 0 XP_011507382 (OMIM: 609209) PREDICTED: influenza v ( 560) 3726 707.2 4e-203 XP_005244900 (OMIM: 609209) PREDICTED: influenza v ( 424) 2930 558.4 1.8e-158 XP_016855573 (OMIM: 609209) PREDICTED: influenza v ( 431) 2906 554.0 4.1e-157 NP_001244124 (OMIM: 605775,614495) kelch-like prot ( 505) 642 131.2 9e-30 NP_001244123 (OMIM: 605775,614495) kelch-like prot ( 555) 642 131.2 9.6e-30 NP_059111 (OMIM: 605775,614495) kelch-like protein ( 587) 642 131.2 1e-29 XP_005260230 (OMIM: 606016) PREDICTED: kelch-like ( 624) 590 121.5 8.8e-27 XP_005260231 (OMIM: 606016) PREDICTED: kelch-like ( 624) 590 121.5 8.8e-27 NP_036421 (OMIM: 606016) kelch-like ECH-associated ( 624) 590 121.5 8.8e-27 XP_011526754 (OMIM: 606016) PREDICTED: kelch-like ( 624) 590 121.5 8.8e-27 NP_987096 (OMIM: 606016) kelch-like ECH-associated ( 624) 590 121.5 8.8e-27 NP_001317952 (OMIM: 605774) kelch-like protein 2 i ( 427) 584 120.3 1.4e-26 NP_067646 (OMIM: 614522) kelch-like protein 12 iso ( 568) 585 120.6 1.6e-26 NP_001317953 (OMIM: 605774) kelch-like protein 2 i ( 496) 584 120.3 1.6e-26 XP_011529878 (OMIM: 605774) PREDICTED: kelch-like ( 496) 584 120.3 1.6e-26 XP_016863165 (OMIM: 605774) PREDICTED: kelch-like ( 505) 584 120.3 1.6e-26 NP_001154994 (OMIM: 605774) kelch-like protein 2 i ( 505) 584 120.3 1.6e-26 NP_001289980 (OMIM: 614522) kelch-like protein 12 ( 606) 585 120.6 1.7e-26 XP_011508137 (OMIM: 614522) PREDICTED: kelch-like ( 623) 585 120.6 1.7e-26 XP_016863163 (OMIM: 605774) PREDICTED: kelch-like ( 555) 584 120.4 1.8e-26 NP_009177 (OMIM: 605774) kelch-like protein 2 isof ( 593) 584 120.4 1.8e-26 NP_001154993 (OMIM: 605774) kelch-like protein 2 i ( 597) 584 120.4 1.9e-26 XP_011529874 (OMIM: 605774) PREDICTED: kelch-like ( 633) 584 120.4 1.9e-26 NP_001316525 (OMIM: 608778,615081) kelch-like prot ( 520) 578 119.2 3.6e-26 NP_689680 (OMIM: 608778,615081) kelch-like protein ( 608) 578 119.3 4.1e-26 NP_001316524 (OMIM: 608778,615081) kelch-like prot ( 608) 578 119.3 4.1e-26 NP_001278936 (OMIM: 611967) kelch-like protein 8 i ( 437) 567 117.1 1.3e-25 NP_001278935 (OMIM: 611967) kelch-like protein 8 i ( 544) 567 117.2 1.6e-25 NP_001278932 (OMIM: 611967) kelch-like protein 8 i ( 620) 567 117.2 1.7e-25 NP_065854 (OMIM: 611967) kelch-like protein 8 isof ( 620) 567 117.2 1.7e-25 NP_001026880 (OMIM: 611119,612943,617055) kelch-li ( 586) 511 106.8 2.3e-22 NP_001165125 (OMIM: 608064) kelch-like protein 5 i ( 568) 491 103.0 3e-21 NP_950240 (OMIM: 608064) kelch-like protein 5 isof ( 694) 491 103.1 3.5e-21 NP_001007076 (OMIM: 608064) kelch-like protein 5 i ( 709) 491 103.1 3.6e-21 NP_057074 (OMIM: 608064) kelch-like protein 5 isof ( 755) 491 103.1 3.7e-21 XP_016863765 (OMIM: 608064) PREDICTED: kelch-like ( 788) 491 103.1 3.9e-21 XP_011512002 (OMIM: 608064) PREDICTED: kelch-like ( 788) 491 103.1 3.9e-21 XP_011512003 (OMIM: 608064) PREDICTED: kelch-like ( 788) 491 103.1 3.9e-21 XP_016863764 (OMIM: 608064) PREDICTED: kelch-like ( 788) 491 103.1 3.9e-21 XP_005262712 (OMIM: 608064) PREDICTED: kelch-like ( 789) 491 103.1 3.9e-21 XP_011512001 (OMIM: 608064) PREDICTED: kelch-like ( 804) 491 103.1 3.9e-21 XP_016863763 (OMIM: 608064) PREDICTED: kelch-like ( 804) 491 103.1 3.9e-21 XP_016863762 (OMIM: 608064) PREDICTED: kelch-like ( 804) 491 103.1 3.9e-21 XP_016867928 (OMIM: 611119,612943,617055) PREDICTE ( 564) 487 102.3 5.1e-21 XP_005247609 (OMIM: 611295) PREDICTED: kelch-like ( 600) 464 98.0 1e-19 XP_005247610 (OMIM: 611295) PREDICTED: kelch-like ( 600) 464 98.0 1e-19 XP_016862148 (OMIM: 611295) PREDICTED: kelch-like ( 600) 464 98.0 1e-19 XP_005247611 (OMIM: 611295) PREDICTED: kelch-like ( 600) 464 98.0 1e-19 >>NP_006460 (OMIM: 609209) influenza virus NS1A-binding (642 aa) initn: 4391 init1: 4391 opt: 4391 Z-score: 4438.2 bits: 831.5 E(85289): 0 Smith-Waterman score: 4391; 100.0% identity (100.0% similar) in 642 aa overlap (1-642:1-642) 10 20 30 40 50 60 pF1KA0 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 CGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 MLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 AEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 GGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 NCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAG 550 560 570 580 590 600 610 620 630 640 pF1KA0 IATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF :::::::::::::::::::::::::::::::::::::::::: NP_006 IATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF 610 620 630 640 >>XP_011507381 (OMIM: 609209) PREDICTED: influenza virus (649 aa) initn: 2699 init1: 2699 opt: 4367 Z-score: 4413.9 bits: 827.0 E(85289): 0 Smith-Waterman score: 4367; 98.9% identity (98.9% similar) in 649 aa overlap (1-642:1-649) 10 20 30 40 50 60 pF1KA0 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 MLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQ 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 AEVFGSDDDHIQFVQ-------KKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVA ::::::::::::::: :::::::::::::::::::::::::::::::::::::: XP_011 AEVFGSDDDHIQFVQVHIAQSEKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 SEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 MQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 MGQLYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGQLYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 YGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYN 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 PENNTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PENNTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMT 550 560 570 580 590 600 600 610 620 630 640 pF1KA0 SPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF 610 620 630 640 >>XP_011507382 (OMIM: 609209) PREDICTED: influenza virus (560 aa) initn: 2699 init1: 2699 opt: 3726 Z-score: 3767.8 bits: 707.2 E(85289): 4e-203 Smith-Waterman score: 3726; 98.6% identity (98.7% similar) in 556 aa overlap (94-642:5-560) 70 80 90 100 110 120 pF1KA0 DSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGD .::::::::::::::::::::::::::::: XP_011 MFDFRLKADKELVKDVYSAAKKLKMDRVKQVCGD 10 20 30 130 140 150 160 170 180 pF1KA0 YLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLE 40 50 60 70 80 90 190 200 210 220 230 240 pF1KA0 DNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEV 100 110 120 130 140 150 250 260 270 280 290 pF1KA0 FGSDDDHIQFVQ-------KKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEK :::::::::::: ::::::::::::::::::::::::::::::::::::::::: XP_011 FGSDDDHIQFVQVHIAQSEKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEK 160 170 180 190 200 210 300 310 320 330 340 350 pF1KA0 TSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQY 220 230 240 250 260 270 360 370 380 390 400 410 pF1KA0 ARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQ 280 290 300 310 320 330 420 430 440 450 460 470 pF1KA0 LYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQ 340 350 360 370 380 390 480 490 500 510 520 530 pF1KA0 KGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPEN 400 410 420 430 440 450 540 550 560 570 580 590 pF1KA0 NTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPR 460 470 480 490 500 510 600 610 620 630 640 pF1KA0 SNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF :::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF 520 530 540 550 560 >>XP_005244900 (OMIM: 609209) PREDICTED: influenza virus (424 aa) initn: 2930 init1: 2930 opt: 2930 Z-score: 2966.0 bits: 558.4 E(85289): 1.8e-158 Smith-Waterman score: 2930; 100.0% identity (100.0% similar) in 423 aa overlap (220-642:2-424) 190 200 210 220 230 240 pF1KA0 SNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEVFGSDDD :::::::::::::::::::::::::::::: XP_005 MVQTLYYSADHKLLDGNLLDGQAEVFGSDDD 10 20 30 250 260 270 280 290 300 pF1KA0 HIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLD 40 50 60 70 80 90 310 320 330 340 350 360 pF1KA0 GIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSGLGTAEMNGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSGLGTAEMNGK 100 110 120 130 140 150 370 380 390 400 410 420 pF1KA0 LIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDD 160 170 180 190 200 210 430 440 450 460 470 480 pF1KA0 LSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVT 220 230 240 250 260 270 490 500 510 520 530 540 pF1KA0 KLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVAR 280 290 300 310 320 330 550 560 570 580 590 600 pF1KA0 RGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIATVGNTIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIATVGNTIY 340 350 360 370 380 390 610 620 630 640 pF1KA0 AVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF ::::::::::::::::::::::::::::::::: XP_005 AVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF 400 410 420 >>XP_016855573 (OMIM: 609209) PREDICTED: influenza virus (431 aa) initn: 2699 init1: 2699 opt: 2906 Z-score: 2941.6 bits: 554.0 E(85289): 4.1e-157 Smith-Waterman score: 2906; 98.4% identity (98.4% similar) in 430 aa overlap (220-642:2-431) 190 200 210 220 230 240 pF1KA0 SNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEVFGSDDD :::::::::::::::::::::::::::::: XP_016 MVQTLYYSADHKLLDGNLLDGQAEVFGSDDD 10 20 30 250 260 270 280 290 300 pF1KA0 HIQFVQ-------KKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNNTY :::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HIQFVQVHIAQSEKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNNTY 40 50 60 70 80 90 310 320 330 340 350 360 pF1KA0 LCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSGLG 100 110 120 130 140 150 370 380 390 400 410 420 pF1KA0 TAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGG 160 170 180 190 200 210 430 440 450 460 470 480 pF1KA0 SNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNC 220 230 240 250 260 270 490 500 510 520 530 540 pF1KA0 DVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLI 280 290 300 310 320 330 550 560 570 580 590 600 pF1KA0 APMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIA 340 350 360 370 380 390 610 620 630 640 pF1KA0 TVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF :::::::::::::::::::::::::::::::::::::::: XP_016 TVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF 400 410 420 430 >>NP_001244124 (OMIM: 605775,614495) kelch-like protein (505 aa) initn: 383 init1: 383 opt: 642 Z-score: 655.5 bits: 131.2 E(85289): 9e-30 Smith-Waterman score: 750; 28.6% identity (58.6% similar) in 539 aa overlap (73-608:9-505) 50 60 70 80 90 100 pF1KA0 MLAHRAVLACCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELV ... :.. ... :..: :::.... .: : NP_001 MSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENV 10 20 30 110 120 130 140 150 160 pF1KA0 KDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLL . . ::. :.. :.: : :.: :.. :.:.. : ::. . ::....:: ..:. NP_001 QVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFP 40 50 60 70 80 90 170 180 190 200 210 220 pF1KA0 QISEEEEFLKLPRLKLEVMLE-DNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQ .. ::::.: .. .. :.. . :. :.. ::.:.. . . .:::.:. NP_001 EVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVR 100 110 120 130 140 150 230 240 250 260 270 280 pF1KA0 TLYYSADHKLLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNAT :: . : .: :... .: ... : NP_001 L-------PLLPRDYL-------------VQTVEEEALIKN-----NNTCKDFLIEAMKY 160 170 180 190 290 300 310 320 330 340 pF1KA0 VQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLS-FE : . .. . .:. : . : . .: . :. .:: .:. .. NP_001 HLLPLDQRLLIKNPRTKPRTPVSLPKV-----MIVVGGQ---------APKAIRSVECYD 200 210 220 230 350 360 370 380 390 400 pF1KA0 MQQDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAP ...:. . : . :.:. . : :.. :.::.: .:::. :. :.:. .: NP_001 FEEDRWDQIAELPSRRCRAGV--VFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIAS 240 250 260 270 280 290 410 420 430 440 450 460 pF1KA0 MRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCA :. :. . ::: ::.::: .: : :. : :. . ..:. : . : : ..:: . NP_001 MQERRSTLGAAVLNDLLYAVGGFDG-STGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGV 300 310 320 330 340 350 470 480 490 500 510 520 pF1KA0 LNGKLYIVGGSDPYGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGA ..:::: ::: : ... :.. . ..:.:. : : .. :: ..: :.: :: :: NP_001 VEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGH 360 370 380 390 400 410 530 540 550 560 570 580 pF1KA0 ESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYD .. ..:: :.: .::: .: ::. ::.::: ..:: :.: :: ::: .. ::.:. NP_001 DGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYN 420 430 440 450 460 470 590 600 610 620 630 pF1KA0 PTRNEWKMMG-NMTSPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKI :. ..: .. ::.. :: ::.:.. ... NP_001 PVTDKWTLLPTNMSTGRSYAGVAVIHKSL 480 490 500 >>NP_001244123 (OMIM: 605775,614495) kelch-like protein (555 aa) initn: 1066 init1: 383 opt: 642 Z-score: 655.0 bits: 131.2 E(85289): 9.6e-30 Smith-Waterman score: 869; 29.3% identity (59.3% similar) in 590 aa overlap (22-608:8-555) 10 20 30 40 50 60 pF1KA0 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEI .: ::.. .::: . . :. :::.::: ::::. . NP_001 MGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCAM 10 20 30 40 70 80 90 100 110 120 pF1KA0 FNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQV :..: . ..... :.. ... :..: :::.... .: :. . ::. :.. :.: NP_001 FTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KA0 CGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEV : :.: :.. :.:.. : ::. . ::....:: ..:. .. ::::.: .. NP_001 CCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVCS 110 120 130 140 150 160 190 200 210 220 230 pF1KA0 MLE-DNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDG .. :.. . :. :.. ::.:.. . . .:::.:. :: . : NP_001 LISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRL-------PLLPRDYL-- 170 180 190 200 210 240 250 260 270 280 290 pF1KA0 QAEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSN .: :... .: ... : : . .. . .:. NP_001 -----------VQTVEEEALIKN-----NNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKP 220 230 240 250 260 300 310 320 330 340 350 pF1KA0 NTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLS-FEMQQDELIEKPMSPMQYAR : . : . .: . :. .:: .:. .....:. . : . : NP_001 RTPVSLPKV-----MIVVGGQ---------APKAIRSVECYDFEEDRWDQIAELPSRRCR 270 280 290 300 360 370 380 390 400 410 pF1KA0 SGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLY .:. . : :.. :.::.: .:::. :. :.:. .: :. :. . ::: :: NP_001 AGV--VFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLY 310 320 330 340 350 360 420 430 440 450 460 470 pF1KA0 VVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKG .::: .: : :. : :. . ..:. : . : : ..:: ...:::: ::: : ... NP_001 AVGGFDG-STGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQC 370 380 390 400 410 420 480 490 500 510 520 530 pF1KA0 LKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNT :.. . ..:.:. : : .. :: ..: :.: :: :: .. ..:: :.: .:: NP_001 LSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNT 430 440 450 460 470 480 540 550 560 570 580 590 pF1KA0 WTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMG-NMTSPRS : .: ::. ::.::: ..:: :.: :: ::: .. ::.:.:. ..: .. ::.. :: NP_001 WKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRS 490 500 510 520 530 540 600 610 620 630 640 pF1KA0 NAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF ::.:.. ... NP_001 YAGVAVIHKSL 550 >>NP_059111 (OMIM: 605775,614495) kelch-like protein 3 i (587 aa) initn: 909 init1: 383 opt: 642 Z-score: 654.6 bits: 131.2 E(85289): 1e-29 Smith-Waterman score: 869; 29.3% identity (59.3% similar) in 590 aa overlap (22-608:40-587) 10 20 30 40 50 pF1KA0 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLA .: ::.. .::: . . :. :::.::: NP_059 SQTLIQAGDDEKNQRTITVNPAHMGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 CCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKK ::::. .:..: . ..... :.. ... :..: :::.... .: :. . ::. NP_059 ACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 LKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFL :.. :.: : :.: :.. :.:.. : ::. . ::....:: ..:. .. :::: NP_059 LQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 KLPRLKLEVMLE-DNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHK .: .. .. :.. . :. :.. ::.:.. . . .:::.:. NP_059 SLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRL-------P 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 LLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWK :: . : .: :... .: ... : : . NP_059 LLPRDYL-------------VQTVEEEALIKN-----NNTCKDFLIEAMKYHLLPLDQRL 250 260 270 280 300 310 320 330 340 pF1KA0 IVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLS-FEMQQDELIEK .. . .:. : . : . .: . :. .:: .:. .....:. . NP_059 LIKNPRTKPRTPVSLPKV-----MIVVGGQ---------APKAIRSVECYDFEEDRWDQI 290 300 310 320 330 350 360 370 380 390 400 pF1KA0 PMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQ : . :.:. . : :.. :.::.: .:::. :. :.:. .: :. :. . NP_059 AELPSRRCRAGV--VFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLG 340 350 360 370 380 410 420 430 440 450 460 pF1KA0 MAVLMGQLYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVG ::: ::.::: .: : :. : :. . ..:. : . : : ..:: ...:::: :: NP_059 AAVLNDLLYAVGGFDG-STGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVG 390 400 410 420 430 440 470 480 490 500 510 520 pF1KA0 GSDPYGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTV : : ... :.. . ..:.:. : : .. :: ..: :.: :: :: .. ..: NP_059 GYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSV 450 460 470 480 490 500 530 540 550 560 570 580 pF1KA0 ERYNPENNTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMM : :.: .::: .: ::. ::.::: ..:: :.: :: ::: .. ::.:.:. ..: .. NP_059 EVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLL 510 520 530 540 550 560 590 600 610 620 630 640 pF1KA0 G-NMTSPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF ::.. :: ::.:.. ... NP_059 PTNMSTGRSYAGVAVIHKSL 570 580 >>XP_005260230 (OMIM: 606016) PREDICTED: kelch-like ECH- (624 aa) initn: 1110 init1: 455 opt: 590 Z-score: 601.8 bits: 121.5 E(85289): 8.8e-27 Smith-Waterman score: 769; 28.9% identity (58.2% similar) in 584 aa overlap (12-580:57-585) 10 20 30 40 pF1KA0 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGH :. ... . .: :: : :.::: ::: . XP_005 AGDAVMYASTECKAEVTPSQHGNRTFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQ 30 40 50 60 70 80 50 60 70 80 90 pF1KA0 E-----MLAHRAVLACCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLK . ..::..::: :: . .:.. .:. :... ..:...: :...::::... XP_005 DAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASIS 90 100 110 120 130 140 100 110 120 130 140 150 pF1KA0 ADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAY .. : :...: ..: : ..:.:.:....: .. :. ::: .: .: ... : XP_005 MGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREY 150 160 170 180 190 200 160 170 180 190 200 210 pF1KA0 IQEHLLQISEEEEFLKLPRLKLEVML-EDNVCLPSNGKLYTKVINWVQRSIWENGDSLEE : :. .....:::..: . .: ... .:.. . ..... ::::. . :. XP_005 IYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDC-------EQ 210 220 230 240 250 220 230 240 250 260 270 pF1KA0 LMEEVQTLYYSADHKLLDGNLLDGQ---AEVFGSDDDHIQFVQKKPPRENGHKQISSSST ::.: .. . : :.:. : :.. ::. ... : . . :: .. XP_005 RRFYVQALLRAVRCHSLTPNFLQMQLQKCEILQSDSRCKDYLVKIFEELTLHKP--TQVM 260 270 280 290 300 310 280 290 300 310 320 330 pF1KA0 GCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPK : ..:: . .:. : :: XP_005 PC--------RAPK------------------------VGRLIYTAGGYFRQS------- 320 330 340 350 360 370 380 pF1KA0 LSKSLSFEMQQDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRT----VECY :: ... .. .. .. .: ::::. ..: : :.:: : : ..:: XP_005 LSYLEAYNPSDGTWLR--LADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCY 340 350 360 370 380 390 390 400 410 420 430 440 pF1KA0 NPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNG--HSDDLSCGEMYDSNIDDWIPV :: :..:: ::: .:: :. ..:. :..:.::::.: : ... : :. . :.: : XP_005 NPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSV---ERYEPERDEWHLV 400 410 420 430 440 450 450 460 470 480 490 500 pF1KA0 PELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSA . : : ..:: .:: :: ::: : : . :.. . . : . : . .: : .. XP_005 APMLTRRIGVGVAVLNRLLYAVGGFD--GTNRLNSAECYYPERNEWRMITAMNTIRSGAG 460 470 480 490 500 510 510 520 530 540 550 560 pF1KA0 VCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLNGKLFVCGG :: : . .: :: .. . ::.::::. :..:::..:::. : . :..: .:...: :: XP_005 VCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGG 520 530 540 550 560 570 570 580 590 600 610 620 pF1KA0 FDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVY .:: .. :: :: XP_005 YDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQQNCTC 580 590 600 610 620 >>XP_005260231 (OMIM: 606016) PREDICTED: kelch-like ECH- (624 aa) initn: 1110 init1: 455 opt: 590 Z-score: 601.8 bits: 121.5 E(85289): 8.8e-27 Smith-Waterman score: 769; 28.9% identity (58.2% similar) in 584 aa overlap (12-580:57-585) 10 20 30 40 pF1KA0 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGH :. ... . .: :: : :.::: ::: . XP_005 AGDAVMYASTECKAEVTPSQHGNRTFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQ 30 40 50 60 70 80 50 60 70 80 90 pF1KA0 E-----MLAHRAVLACCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLK . ..::..::: :: . .:.. .:. :... ..:...: :...::::... XP_005 DAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASIS 90 100 110 120 130 140 100 110 120 130 140 150 pF1KA0 ADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAY .. : :...: ..: : ..:.:.:....: .. :. ::: .: .: ... : XP_005 MGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREY 150 160 170 180 190 200 160 170 180 190 200 210 pF1KA0 IQEHLLQISEEEEFLKLPRLKLEVML-EDNVCLPSNGKLYTKVINWVQRSIWENGDSLEE : :. .....:::..: . .: ... .:.. . ..... ::::. . :. XP_005 IYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDC-------EQ 210 220 230 240 250 220 230 240 250 260 270 pF1KA0 LMEEVQTLYYSADHKLLDGNLLDGQ---AEVFGSDDDHIQFVQKKPPRENGHKQISSSST ::.: .. . : :.:. : :.. ::. ... : . . :: .. XP_005 RRFYVQALLRAVRCHSLTPNFLQMQLQKCEILQSDSRCKDYLVKIFEELTLHKP--TQVM 260 270 280 290 300 310 280 290 300 310 320 330 pF1KA0 GCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPK : ..:: . .:. : :: XP_005 PC--------RAPK------------------------VGRLIYTAGGYFRQS------- 320 330 340 350 360 370 380 pF1KA0 LSKSLSFEMQQDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRT----VECY :: ... .. .. .. .: ::::. ..: : :.:: : : ..:: XP_005 LSYLEAYNPSDGTWLR--LADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCY 340 350 360 370 380 390 390 400 410 420 430 440 pF1KA0 NPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNG--HSDDLSCGEMYDSNIDDWIPV :: :..:: ::: .:: :. ..:. :..:.::::.: : ... : :. . :.: : XP_005 NPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSV---ERYEPERDEWHLV 400 410 420 430 440 450 450 460 470 480 490 500 pF1KA0 PELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSA . : : ..:: .:: :: ::: : : . :.. . . : . : . .: : .. XP_005 APMLTRRIGVGVAVLNRLLYAVGGFD--GTNRLNSAECYYPERNEWRMITAMNTIRSGAG 460 470 480 490 500 510 510 520 530 540 550 560 pF1KA0 VCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLNGKLFVCGG :: : . .: :: .. . ::.::::. :..:::..:::. : . :..: .:...: :: XP_005 VCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGG 520 530 540 550 560 570 570 580 590 600 610 620 pF1KA0 FDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVY .:: .. :: :: XP_005 YDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQQNCTC 580 590 600 610 620 642 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:50:18 2016 done: Wed Nov 2 19:50:20 2016 Total Scan time: 8.920 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]