FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0852, 970 aa 1>>>pF1KA0852 970 - 970 aa - 970 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.4666+/-0.00118; mu= -10.5305+/- 0.071 mean_var=369.3985+/-75.577, 0's: 0 Z-trim(112.7): 24 B-trim: 109 in 1/53 Lambda= 0.066731 statistics sampled from 13423 (13440) to 13423 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.413), width: 16 Scan time: 5.140 The best scores are: opt bits E(32554) CCDS33636.1 MORC2 gene_id:22880|Hs108|chr22 ( 970) 6411 631.9 1.8e-180 CCDS77668.1 MORC2 gene_id:22880|Hs108|chr22 (1032) 6411 631.9 1.9e-180 CCDS2955.1 MORC1 gene_id:27136|Hs108|chr3 ( 984) 975 108.6 6.4e-23 >>CCDS33636.1 MORC2 gene_id:22880|Hs108|chr22 (970 aa) initn: 6411 init1: 6411 opt: 6411 Z-score: 3353.4 bits: 631.9 E(32554): 1.8e-180 Smith-Waterman score: 6411; 100.0% identity (100.0% similar) in 970 aa overlap (1-970:1-970) 10 20 30 40 50 60 pF1KA0 MLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 EVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 YAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EEKAREAESKARTLEVRLGGDLTRDSRVMLRQVQNRAITLRREADVKKRIKEAKQRALKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EEKAREAESKARTLEVRLGGDLTRDSRVMLRQVQNRAITLRREADVKKRIKEAKQRALKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 PKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 PTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 QKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 QKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 TEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 TEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 STSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 STSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 TESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVKEEKKDSNELSDSAGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 TESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVKEEKKDSNELSDSAGE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 EDSADLKRAQKDKGLHVEVRVNREWYTGRVTAVEVGKHVVRWKVKFDYVPTDTTPRDRWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EDSADLKRAQKDKGLHVEVRVNREWYTGRVTAVEVGKHVVRWKVKFDYVPTDTTPRDRWV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 EKGSEDVRLMKPPSPEHQSLDTQQEGGEEEVGPVAQQAIAVAEPSTSECLRIEPDTTALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EKGSEDVRLMKPPSPEHQSLDTQQEGGEEEVGPVAQQAIAVAEPSTSECLRIEPDTTALS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 TNHETIDLLVQILRNCLRYFLPPSFPISKKQLSAMNSDELISFPLKEYFKQYEVGLQNLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 TNHETIDLLVQILRNCLRYFLPPSFPISKKQLSAMNSDELISFPLKEYFKQYEVGLQNLC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 NSYQSRADSRAKASEESLRTSERKLRETEEKLQKLRTNIVALLQKVQEDIDINTDDELDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 NSYQSRADSRAKASEESLRTSERKLRETEEKLQKLRTNIVALLQKVQEDIDINTDDELDA 910 920 930 940 950 960 970 pF1KA0 YIEDLITKGD :::::::::: CCDS33 YIEDLITKGD 970 >>CCDS77668.1 MORC2 gene_id:22880|Hs108|chr22 (1032 aa) initn: 6411 init1: 6411 opt: 6411 Z-score: 3353.0 bits: 631.9 E(32554): 1.9e-180 Smith-Waterman score: 6411; 100.0% identity (100.0% similar) in 970 aa overlap (1-970:63-1032) 10 20 30 pF1KA0 MLCFLDDGAGMDPSDAASVIQFGKSAKRTP :::::::::::::::::::::::::::::: CCDS77 LAELVDNARDADATRIDIYAERREDLRGGFMLCFLDDGAGMDPSDAASVIQFGKSAKRTP 40 50 60 70 80 90 40 50 60 70 80 90 pF1KA0 ESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNA 100 110 120 130 140 150 100 110 120 130 140 150 pF1KA0 RTREPVTDNVEKFAIETELIYKYSPFRTEEEVMTQFMKIPGDSGTLVIIFNLKLMDNGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RTREPVTDNVEKFAIETELIYKYSPFRTEEEVMTQFMKIPGDSGTLVIIFNLKLMDNGEP 160 170 180 190 200 210 160 170 180 190 200 210 pF1KA0 ELDIISNPRDIQMAETSPEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ELDIISNPRDIQMAETSPEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLY 220 230 240 250 260 270 220 230 240 250 260 270 pF1KA0 KPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRLGGDLTRDSRVML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 KPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRLGGDLTRDSRVML 280 290 300 310 320 330 280 290 300 310 320 330 pF1KA0 RQVQNRAITLRREADVKKRIKEAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RQVQNRAITLRREADVKKRIKEAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIK 340 350 360 370 380 390 340 350 360 370 380 390 pF1KA0 MYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWK 400 410 420 430 440 450 400 410 420 430 440 450 pF1KA0 DIAIAQRGIIKFWDEFGYLSANWNQPPSSELRYKRRRAMEIPTTIQCDLCLKWRTLPFQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DIAIAQRGIIKFWDEFGYLSANWNQPPSSELRYKRRRAMEIPTTIQCDLCLKWRTLPFQL 460 470 480 490 500 510 460 470 480 490 500 510 pF1KA0 SSVEKDYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SSVEKDYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQ 520 530 540 550 560 570 520 530 540 550 560 570 pF1KA0 EKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 EKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSL 580 590 600 610 620 630 580 590 600 610 620 630 pF1KA0 PTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLV 640 650 660 670 680 690 640 650 660 670 680 690 pF1KA0 QQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEA 700 710 720 730 740 750 700 710 720 730 740 750 pF1KA0 ERRKERCKRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNREWYTGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ERRKERCKRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNREWYTGRV 760 770 780 790 800 810 760 770 780 790 800 810 pF1KA0 TAVEVGKHVVRWKVKFDYVPTDTTPRDRWVEKGSEDVRLMKPPSPEHQSLDTQQEGGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TAVEVGKHVVRWKVKFDYVPTDTTPRDRWVEKGSEDVRLMKPPSPEHQSLDTQQEGGEEE 820 830 840 850 860 870 820 830 840 850 860 870 pF1KA0 VGPVAQQAIAVAEPSTSECLRIEPDTTALSTNHETIDLLVQILRNCLRYFLPPSFPISKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VGPVAQQAIAVAEPSTSECLRIEPDTTALSTNHETIDLLVQILRNCLRYFLPPSFPISKK 880 890 900 910 920 930 880 890 900 910 920 930 pF1KA0 QLSAMNSDELISFPLKEYFKQYEVGLQNLCNSYQSRADSRAKASEESLRTSERKLRETEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QLSAMNSDELISFPLKEYFKQYEVGLQNLCNSYQSRADSRAKASEESLRTSERKLRETEE 940 950 960 970 980 990 940 950 960 970 pF1KA0 KLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD :::::::::::::::::::::::::::::::::::::::: CCDS77 KLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD 1000 1010 1020 1030 >>CCDS2955.1 MORC1 gene_id:27136|Hs108|chr3 (984 aa) initn: 1797 init1: 722 opt: 975 Z-score: 525.0 bits: 108.6 E(32554): 6.4e-23 Smith-Waterman score: 1702; 35.4% identity (61.6% similar) in 972 aa overlap (1-970:62-955) 10 20 30 pF1KA0 MLCFLDDGAGMDPSDAASVIQFGKSAKRTP :::::::: ::.: .:...: ::.: :: CCDS29 LAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEEASDIIYFGRSKKRLS 40 50 60 70 80 90 40 50 60 70 80 90 pF1KA0 ESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNA ::::::::::::::::::::::::::.::::.:.:.:: :::...::.::.:.: CCDS29 TLKFIGQYGNGLKSGSMRIGKDFILFTKKEETMTCVFFSQTFCEEESLSEVVVPMPSWLI 100 110 120 130 140 150 100 110 120 130 140 150 pF1KA0 RTREPVTDNVEKFAIETELIYKYSPFRTEEEVMTQFMKIPGDSGTLVIIFNLKLMDNGEP :::: :::. .:::.: .:::::::.:: :.: :: : : :::..:.::::. :::: CCDS29 RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGKCGTLLVIYNLKLLLNGEP 160 170 180 190 200 210 160 170 180 190 200 210 pF1KA0 ELDIISNPRDIQMAETSPEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLY :::. .. .:: :: . . : : :::::..:::..: :::::....:.::.: ::: CCDS29 ELDVKTDKEDILMAGALED--FPARWSFRAYTSVLYFNPWMRIFIQAKRVKTKHLCYCLY 220 230 240 250 260 220 230 240 250 260 270 pF1KA0 KPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRLGGDLTRDSRVML .:: : :..: :: ..::::::....::: .::. :. . : : CCDS29 RPRKYLYVTSSFKGAFKDEVKKAEEAVKIAESILKEAQIKVNQCD--------RTSLSSA 270 280 290 300 310 320 280 290 300 310 320 330 pF1KA0 RQVQNRAITLRREADVKKRIKEAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIK ..: .::. .....:.. . ::: :: . :.. .:::.:.:. :::::. .:::: CCDS29 KDVLQRAL---EDVEAKQKNLKEKQRELKTARTLSLFYGVNVENRSQAGMFIYSNNRLIK 330 340 350 360 370 340 350 360 370 380 pF1KA0 MYEKVGPQLEGGMACG-GVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYW :.:::: ::. : ::::.:..: :.::.::::.: ...:: :::..::..:.:: CCDS29 MHEKVGSQLKLKSLLGAGVVGIVNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYC 380 390 400 410 420 430 390 400 410 420 430 440 pF1KA0 KDIAIAQRGIIKFWDEFGYLSANWNQPPSSELRYKRRRAMEIPTTIQCDLCLKWRTLPFQ :: .: .:.. : .:::: . . : . ..:.::.:: :: ::::::::::.:: . CCDS29 KDTGINNRNLTLFCNEFGYQNDIDVEKPLNSFQYQRRQAMGIPFIIQCDLCLKWRVLPSS 440 450 460 470 480 490 450 460 470 480 490 500 pF1KA0 LSSVEKDYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQ . ::.. : :.:. ::. .. :. : ..::::. ...::.::: :.. . CCDS29 TNYQEKEFFDIWICANNPNRLENSCHQVECLPSIPLGTMSTISPSKNEKEKQLRESVIKY 500 510 520 530 540 550 510 520 530 540 550 560 pF1KA0 QEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPS :..: : :. : .: .. . : :... . :. : : ... CCDS29 QNRL-AEQQPQPQFIPVD--EITVTSTCLTSAHKENTKTQKIRL--LGDDLKHESLSSFE 560 570 580 590 600 610 570 580 590 600 610 620 pF1KA0 LPTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPL : . : .: :. .: : : ..... :. . CCDS29 LSASR-RGQKRNIEETDSDV--------EYISETKIMK-------------KSMEEKMNS 620 630 640 650 630 640 650 660 670 680 pF1KA0 VQQLSPSLLP-NSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEE :: : :: : : .. .. . .: ... :. : . :.: : . .. CCDS29 QQQRIPVALPENVKLAERSQRSQIANITTVWRAQ------PTEGCLKNAQAASWEMK-RK 660 670 680 690 700 690 700 710 720 730 740 pF1KA0 EAERRKERCKRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNREWYTG .. :.:: :. :... :. .......:.. :. : . . . ... . CCDS29 QSLNFVEECK----VLTEDENTSDSDIILVSDKSNTDVSLKQEKKEIPL-LNQEKQELCN 710 720 730 740 750 750 760 770 780 790 800 pF1KA0 RVTAVEVGKHVVRWKVKFDYVPTDTTPRDRWVEKGSEDVRLMKPPSPEHQSLDTQQEGGE : :.. .. . :: .. :: ::: : : : . . . . . CCDS29 DVLAMKRSSSLPSWKSLLN-VPM-------------EDVNL----SSGHIARVSVSGSCK 760 770 780 790 800 810 820 830 840 850 860 pF1KA0 EEVGPVAQQAIAVAEPSTSECLRIEPDTTALSTNHETIDLLVQILRNCLRYFLPPSFPIS .:...:. : : . ... . .:. . : . .: : .. CCDS29 VASSPASSQSTPVKETVRKLKSKLREILLYFFPEHQLPSELEEPALSCELEQCPEQM--- 810 820 830 840 850 870 880 890 900 910 920 pF1KA0 KKQLSAMNSDELISFPLKEYFKQYEVGLQNLCNSYQSRADSRAKASEESLRTSERKLRET .:.:. : ... . . .: :. . ::.. :.: ..:. .: :: : : . . CCDS29 NKKLK-MCFNQIQNTYMVQYEKKIKRKLQSII--YDS--NTRGIHNEISLGQCENKRKIS 860 870 880 890 900 910 930 940 950 960 970 pF1KA0 EEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD :.::..:: ... ::::.: . .. :.:.: :. . . CCDS29 EDKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEALLKEDNLLFQNNLNKVTIDARHRL 920 930 940 950 960 970 CCDS29 PLEKNEKTSEN 980 970 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:25:56 2016 done: Thu Nov 3 10:25:56 2016 Total Scan time: 5.140 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]