FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0872, 547 aa 1>>>pF1KA0872 547 - 547 aa - 547 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4664+/-0.000821; mu= 5.7391+/- 0.050 mean_var=177.8392+/-35.290, 0's: 0 Z-trim(114.5): 12 B-trim: 0 in 0/53 Lambda= 0.096175 statistics sampled from 15041 (15049) to 15041 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.462), width: 16 Scan time: 4.190 The best scores are: opt bits E(32554) CCDS10925.1 MON1B gene_id:22879|Hs108|chr16 ( 547) 3632 515.9 4.9e-146 CCDS67082.1 MON1B gene_id:22879|Hs108|chr16 ( 401) 2564 367.6 1.6e-101 CCDS67083.1 MON1B gene_id:22879|Hs108|chr16 ( 438) 2562 367.4 2e-101 CCDS2808.2 MON1A gene_id:84315|Hs108|chr3 ( 652) 946 143.2 8.8e-34 CCDS46830.1 MON1A gene_id:84315|Hs108|chr3 ( 490) 473 77.5 4e-14 >>CCDS10925.1 MON1B gene_id:22879|Hs108|chr16 (547 aa) initn: 3632 init1: 3632 opt: 3632 Z-score: 2735.2 bits: 515.9 E(32554): 4.9e-146 Smith-Waterman score: 3632; 100.0% identity (100.0% similar) in 547 aa overlap (1-547:1-547) 10 20 30 40 50 60 pF1KA0 MEVGGDTAAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEETGSKDKDQPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MEVGGDTAAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEETGSKDKDQPPSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SPPPQSEALSSTSRLWSPAAPENSPTCSPESSSGGQGGDPSDEEWRSQRKHVFVLSEAGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SPPPQSEALSSTSRLWSPAAPENSPTCSPESSSGGQGGDPSDEEWRSQRKHVFVLSEAGK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 QSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 GALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 HAMAACRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 HAMAACRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 PDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 WVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 WVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAH 490 500 510 520 530 540 pF1KA0 NGLFTGL ::::::: CCDS10 NGLFTGL >>CCDS67082.1 MON1B gene_id:22879|Hs108|chr16 (401 aa) initn: 2564 init1: 2564 opt: 2564 Z-score: 1936.3 bits: 367.6 E(32554): 1.6e-101 Smith-Waterman score: 2564; 99.2% identity (99.7% similar) in 392 aa overlap (156-547:10-401) 130 140 150 160 170 180 pF1KA0 YGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTSQSAAQ . .::::::::::::::::::::::::::: CCDS67 MVSGQLRFGVKTEDHKLVFLQQGPLLLVAMSRTSQSAAQ 10 20 30 190 200 210 220 230 240 pF1KA0 LRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDPGALLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 LRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDPGALLL 40 50 60 70 80 90 250 260 270 280 290 300 pF1KA0 GAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLDPADLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 GAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLDPADLQ 100 110 120 130 140 150 310 320 330 340 350 360 pF1KA0 LLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAFHAMAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 LLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAFHAMAA 160 170 180 190 200 210 370 380 390 400 410 420 pF1KA0 CRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDIPDHHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 CRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDIPDHHR 220 230 240 250 260 270 430 440 450 460 470 480 pF1KA0 QLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 QLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSK 280 290 300 310 320 330 490 500 510 520 530 540 pF1KA0 FELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAHNGLFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 FELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAHNGLFT 340 350 360 370 380 390 pF1KA0 GL :: CCDS67 GL 400 >>CCDS67083.1 MON1B gene_id:22879|Hs108|chr16 (438 aa) initn: 2886 init1: 2562 opt: 2562 Z-score: 1934.3 bits: 367.4 E(32554): 2e-101 Smith-Waterman score: 2672; 80.1% identity (80.1% similar) in 547 aa overlap (1-547:1-438) 10 20 30 40 50 60 pF1KA0 MEVGGDTAAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEETGSKDKDQPPSP ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 MEVGGDTAAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEET----------- 10 20 30 40 70 80 90 100 110 120 pF1KA0 SPPPQSEALSSTSRLWSPAAPENSPTCSPESSSGGQGGDPSDEEWRSQRKHVFVLSEAGK CCDS67 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KA0 PIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTS :::::::::::::::::::::: CCDS67 --------------------------------------EDHKLVFLQQGPLLLVAMSRTS 50 60 70 190 200 210 220 230 240 pF1KA0 QSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 QSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDP 80 90 100 110 120 130 250 260 270 280 290 300 pF1KA0 GALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 GALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLD 140 150 160 170 180 190 310 320 330 340 350 360 pF1KA0 PADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 PADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAF 200 210 220 230 240 250 370 380 390 400 410 420 pF1KA0 HAMAACRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 HAMAACRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDI 260 270 280 290 300 310 430 440 450 460 470 480 pF1KA0 PDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 PDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLA 320 330 340 350 360 370 490 500 510 520 530 540 pF1KA0 WVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 WVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAH 380 390 400 410 420 430 pF1KA0 NGLFTGL ::::::: CCDS67 NGLFTGL >>CCDS2808.2 MON1A gene_id:84315|Hs108|chr3 (652 aa) initn: 1262 init1: 548 opt: 946 Z-score: 719.9 bits: 143.2 E(32554): 8.8e-34 Smith-Waterman score: 1390; 46.3% identity (70.6% similar) in 521 aa overlap (16-527:155-652) 10 20 30 40 pF1KA0 MEVGGDTAAPAPGGAEDL---EDTQFPSEEAREGGGVHAVPPDPE ::: :: .. .:: ... :: : CCDS28 RAESPTPGMAQGMEPGAGQEGAMFVHARSYEDLTESEDGAASGDSHKEG--TRGPPPLPT 130 140 150 160 170 180 50 60 70 80 90 100 pF1KA0 D-EGLEETGSKDKDQPPSPSPPPQSEALSSTSRLW-SPAAPENSPTCSPESSSGGQGGDP : . . . :. . : . . : : : ..:. : : . . :. : : :: CCDS28 DMRQISQDFSELSTQLTGVARDLQEEMLPGSSEDWLEPPGAVGRPATEPPRE-GTTEGDE 190 200 210 220 230 240 110 120 130 140 150 pF1KA0 SD--EEWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYA : : :: ..::::::::::::.:::::: ::::.:::::.:::::... .:::.:.: CCDS28 EDATEAWRLHQKHVFVLSEAGKPVYSRYGSEEALSSTMGVMVALVSFLEADKNAIRSIHA 250 260 270 280 290 300 160 170 180 190 200 210 pF1KA0 EDHKLVFLQQGPLLLVAMSRTSQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDL . .:.::....::.:::..:: ::: .: ::: .. ::.: :: :....:: .:::::: CCDS28 DGYKVVFVRRSPLVLVAVARTRQSAQELAQELLYIYYQILSLLTGAQLSHIFQQKQNYDL 310 320 330 340 350 360 220 230 240 250 260 270 pF1KA0 RRLLAGSERTLDRLLDSMEQDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVL ::::.:::: : ::. : .:: ..:.::.::.::: .::...: :.. : .:..:.: CCDS28 RRLLSGSERITDNLLQLMARDP-SFLMGAARCLPLAAAVRDTVSASLQQARARSLVFSIL 370 380 390 400 410 420 280 290 300 310 320 330 pF1KA0 AVGGRLITAAQERNVLAECRLDPADLQLLLDWVGAPA-FAAGEAWAPVCLPRFNPDGFFY . ..:.. ..... . : : ::.::.. ... . : ::::.:::::.:: :::. CCDS28 LARNQLVALVRRKDQF----LHPIDLHLLFNLISSSSSFREGEAWTPVCLPKFNAAGFFH 430 440 450 460 470 340 350 360 370 380 390 pF1KA0 AYVARLDA-MPVCLLLLGTQREAFHAMAACRRLVEDGMHALGAMRALGEAASFSNASSAS :... :. .::::..:.:: : :.. ::: .. .. :: :: :: CCDS28 AHISYLEPDTDLCLLLVSTDREDFFAVSDCRRRFQERLRKRGAHLALREALR-------- 480 490 500 510 520 400 410 420 430 440 450 pF1KA0 APAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLH .: ::: :: : ::::::: .. :::::.::::. :::..:: ::. :: CCDS28 TPYYSVAQVGIPDLRHFLYK-------SKSSGLFTSPEIEAPYTSEEEQERLLGLYQYLH 530 540 550 560 570 580 460 470 480 490 500 510 pF1KA0 ARLHSTSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEE .: :..::::. ::... .:.::::::. :::: : ::: :::.:. .. ::.::..::: CCDS28 SRAHNASRPLKTIYYTGPNENLLAWVTGAFELYMCYSPLGTKASAVSAIHKLMRWIRKEE 590 600 610 620 630 640 520 530 540 pF1KA0 DRLFIRYPPKYSTPPATSTDQAAHNGLFTGL ::::: : : CCDS28 DRLFILTPLTY 650 >>CCDS46830.1 MON1A gene_id:84315|Hs108|chr3 (490 aa) initn: 964 init1: 400 opt: 473 Z-score: 367.1 bits: 77.5 E(32554): 4e-14 Smith-Waterman score: 1073; 47.4% identity (73.6% similar) in 371 aa overlap (159-527:140-490) 130 140 150 160 170 180 pF1KA0 VEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTSQSAAQLRG . .:.::....::.:::..:: ::: .: CCDS46 CLDGTLTPSDGQSMERAESPTPGMAQGMEPDGYKVVFVRRSPLVLVAVARTRQSAQELAQ 110 120 130 140 150 160 190 200 210 220 230 240 pF1KA0 ELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDPGALLLGAV ::: .. ::.: :: :....:: .::::::::::.:::: : ::. : .:: ..:.::. CCDS46 ELLYIYYQILSLLTGAQLSHIFQQKQNYDLRRLLSGSERITDNLLQLMARDP-SFLMGAA 170 180 190 200 210 220 250 260 270 280 290 300 pF1KA0 RCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLDPADLQLLL ::.::: .::...: :.. : .:..:.: . ..:.. ..... . : : ::.::. CCDS46 RCLPLAAAVRDTVSASLQQARARSLVFSILLARNQLVALVRRKDQF----LHPIDLHLLF 230 240 250 260 270 280 310 320 330 340 350 360 pF1KA0 DWVGAPA-FAAGEAWAPVCLPRFNPDGFFYAYVARLDA-MPVCLLLLGTQREAFHAMAAC . ... . : ::::.:::::.:: :::.:... :. .::::..:.:: : :.. : CCDS46 NLISSSSSFREGEAWTPVCLPKFNAAGFFHAHISYLEPDTDLCLLLVSTDREDFFAVSDC 290 300 310 320 330 340 370 380 390 400 410 420 pF1KA0 RRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDIPDHHRQ :: .. .. :: :: :: .: ::: :: : ::::::: .. CCDS46 RRRFQERLRKRGAHLALREALR--------TPYYSVAQVGIPDLRHFLYKS-------KS 350 360 370 380 430 440 450 460 470 480 pF1KA0 LPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSKF :::::.::::. :::..:: ::. ::.: :..::::. ::... .:.::::::. : CCDS46 SGLFTSPEIEAPYTSEEEQERLLGLYQYLHSRAHNASRPLKTIYYTGPNENLLAWVTGAF 390 400 410 420 430 440 490 500 510 520 530 540 pF1KA0 ELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAHNGLFTG ::: : ::: :::.:. .. ::.::..:::::::: : : CCDS46 ELYMCYSPLGTKASAVSAIHKLMRWIRKEEDRLFILTPLTY 450 460 470 480 490 pF1KA0 L 547 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:05:42 2016 done: Fri Nov 4 01:05:42 2016 Total Scan time: 4.190 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]