Result of FASTA (omim) for
pF1KA0878
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0878, 611 aa
1>>>pF1KA0878 611 - 611 aa - 611 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1836+/-0.000444; mu= 19.8176+/- 0.027
mean_var=74.9910+/-16.182, 0's: 0 Z-trim(110.7): 177 B-trim: 1870 in 2/48
Lambda= 0.148105
statistics sampled from 18878 (19101) to 18878 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.593), E-opt: 0.2 (0.224), width: 16
Scan time: 8.270
The best scores are: opt bits E(85289)
NP_055714 (OMIM: 607353) rho-related BTB domain-co ( 611) 4104 887.1 0
XP_016864726 (OMIM: 607353) PREDICTED: rho-related ( 417) 2808 610.0 5e-174
XP_016864725 (OMIM: 607353) PREDICTED: rho-related ( 417) 2808 610.0 5e-174
XP_011541581 (OMIM: 607353) PREDICTED: rho-related ( 489) 1777 389.8 1.2e-107
XP_016872496 (OMIM: 607351) PREDICTED: rho-related ( 576) 370 89.2 4.2e-17
XP_016872494 (OMIM: 607351) PREDICTED: rho-related ( 576) 370 89.2 4.2e-17
XP_016872495 (OMIM: 607351) PREDICTED: rho-related ( 576) 370 89.2 4.2e-17
XP_016872497 (OMIM: 607351) PREDICTED: rho-related ( 576) 370 89.2 4.2e-17
XP_016872492 (OMIM: 607351) PREDICTED: rho-related ( 576) 370 89.2 4.2e-17
XP_016872493 (OMIM: 607351) PREDICTED: rho-related ( 576) 370 89.2 4.2e-17
XP_016872489 (OMIM: 607351) PREDICTED: rho-related ( 696) 370 89.3 4.9e-17
XP_006718148 (OMIM: 607351) PREDICTED: rho-related ( 696) 370 89.3 4.9e-17
NP_055651 (OMIM: 607351) rho-related BTB domain-co ( 696) 370 89.3 4.9e-17
XP_006718147 (OMIM: 607351) PREDICTED: rho-related ( 696) 370 89.3 4.9e-17
NP_001229288 (OMIM: 607351) rho-related BTB domain ( 696) 370 89.3 4.9e-17
XP_011538726 (OMIM: 607351) PREDICTED: rho-related ( 696) 370 89.3 4.9e-17
XP_016872490 (OMIM: 607351) PREDICTED: rho-related ( 696) 370 89.3 4.9e-17
NP_055993 (OMIM: 607352) rho-related BTB domain-co ( 727) 352 85.4 7.3e-16
NP_001153509 (OMIM: 607352) rho-related BTB domain ( 734) 352 85.4 7.3e-16
XP_016868740 (OMIM: 607352) PREDICTED: rho-related ( 749) 352 85.4 7.4e-16
NP_001153508 (OMIM: 607352) rho-related BTB domain ( 749) 352 85.4 7.4e-16
XP_011538728 (OMIM: 607351) PREDICTED: rho-related ( 611) 224 58.0 1.1e-07
XP_016872491 (OMIM: 607351) PREDICTED: rho-related ( 621) 221 57.4 1.7e-07
XP_011538727 (OMIM: 607351) PREDICTED: rho-related ( 621) 221 57.4 1.7e-07
XP_006710686 (OMIM: 147485) PREDICTED: actin-bindi ( 440) 199 52.6 3.4e-06
XP_011539696 (OMIM: 147485) PREDICTED: actin-bindi ( 465) 199 52.6 3.6e-06
XP_005270896 (OMIM: 147485) PREDICTED: actin-bindi ( 465) 199 52.6 3.6e-06
XP_016856699 (OMIM: 147485) PREDICTED: actin-bindi ( 531) 199 52.6 4e-06
NP_001138821 (OMIM: 147485) actin-binding protein ( 582) 199 52.7 4.2e-06
NP_005888 (OMIM: 147485) actin-binding protein IPP ( 584) 199 52.7 4.3e-06
XP_011533437 (OMIM: 103780,607867) PREDICTED: RCC1 ( 402) 187 50.0 1.9e-05
XP_011533436 (OMIM: 103780,607867) PREDICTED: RCC1 ( 531) 187 50.1 2.3e-05
XP_005266498 (OMIM: 103780,607867) PREDICTED: RCC1 ( 531) 187 50.1 2.3e-05
XP_011533435 (OMIM: 103780,607867) PREDICTED: RCC1 ( 531) 187 50.1 2.3e-05
NP_060661 (OMIM: 103780,607867) RCC1 and BTB domai ( 531) 187 50.1 2.3e-05
NP_060267 (OMIM: 608531) BTB/POZ domain-containing ( 525) 185 49.6 3.1e-05
XP_011511240 (OMIM: 611295) PREDICTED: kelch-like ( 600) 180 48.6 7.2e-05
XP_005247609 (OMIM: 611295) PREDICTED: kelch-like ( 600) 180 48.6 7.2e-05
XP_016862148 (OMIM: 611295) PREDICTED: kelch-like ( 600) 180 48.6 7.2e-05
XP_005247613 (OMIM: 611295) PREDICTED: kelch-like ( 600) 180 48.6 7.2e-05
XP_005247610 (OMIM: 611295) PREDICTED: kelch-like ( 600) 180 48.6 7.2e-05
XP_016862149 (OMIM: 611295) PREDICTED: kelch-like ( 600) 180 48.6 7.2e-05
XP_005247611 (OMIM: 611295) PREDICTED: kelch-like ( 600) 180 48.6 7.2e-05
XP_005247612 (OMIM: 611295) PREDICTED: kelch-like ( 600) 180 48.6 7.2e-05
NP_060114 (OMIM: 611295) kelch-like protein 24 [Ho ( 600) 180 48.6 7.2e-05
XP_016862143 (OMIM: 611295) PREDICTED: kelch-like ( 625) 180 48.6 7.5e-05
XP_016862147 (OMIM: 611295) PREDICTED: kelch-like ( 625) 180 48.6 7.5e-05
XP_016862140 (OMIM: 611295) PREDICTED: kelch-like ( 625) 180 48.6 7.5e-05
XP_016862146 (OMIM: 611295) PREDICTED: kelch-like ( 625) 180 48.6 7.5e-05
XP_016862145 (OMIM: 611295) PREDICTED: kelch-like ( 625) 180 48.6 7.5e-05
>>NP_055714 (OMIM: 607353) rho-related BTB domain-contai (611 aa)
initn: 4104 init1: 4104 opt: 4104 Z-score: 4739.6 bits: 887.1 E(85289): 0
Smith-Waterman score: 4104; 99.8% identity (100.0% similar) in 611 aa overlap (1-611:1-611)
10 20 30 40 50 60
pF1KA0 MSIHIVALGNEGDTFHQDNRPSGLIRTYLGRSPLVSGDESSLLLNAASTVARPVFTEYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSIHIVALGNEGDTFHQDNRPSGLIRTYLGRSPLVSGDESSLLLNAASTVARPVFTEYQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SAFGNVKLVVHDCPVWDIFDSDWYTSRNLIGGADIIVIKYNVNDKFSFHEVKDNYIPVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SAFGNVKLVVHDCPVWDIFDSDWYTSRNLIGGADIIVIKYNVNDKFSFHEVKDNYIPVIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RALNSVPVIIAAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RALNSVPVIIAAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FYIGKYFGGVLEYFMIQALNQKTSEKMKKRKMSNSFHGIRPPQLEQPEKMPVLKAEASHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FYIGKYFGGVLEYFMIQALNQKTSEKMKKRKMSNSFHGIRPPQLEQPEKMPVLKAEASHY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 NSDLNNLLFCCQCVDVVFYNPDLKKVVEAHKIVLCAVSHVFMLLFNVKSPTDIQDSSIIR
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
NP_055 NSDLNNLLFCCQCVDVVFYNPNLKKVVEAHKIVLCAVSHVFMLLFNVKSPTDIQDSSIIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TTQDLFAINRDTAFPGASHESSGNPPLRVIVKDALFCSCLSDILRFIYSGAFQWEELEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TTQDLFAINRDTAFPGASHESSGNPPLRVIVKDALFCSCLSDILRFIYSGAFQWEELEED
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 IRKKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLWFYNTSLKFFLNKPMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IRKKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLWFYNTSLKFFLNKPMLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 DVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETFLSFLEYLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETFLSFLEYLYT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNLDIVDLLKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNLDIVDLLKKA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KFHHSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERSFVEKHRWPSNMYLKQLAEYRKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KFHHSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERSFVEKHRWPSNMYLKQLAEYRKY
550 560 570 580 590 600
610
pF1KA0 IHSRKCRCLVM
:::::::::::
NP_055 IHSRKCRCLVM
610
>>XP_016864726 (OMIM: 607353) PREDICTED: rho-related BTB (417 aa)
initn: 2808 init1: 2808 opt: 2808 Z-score: 3245.3 bits: 610.0 E(85289): 5e-174
Smith-Waterman score: 2808; 99.8% identity (100.0% similar) in 417 aa overlap (195-611:1-417)
170 180 190 200 210 220
pF1KA0 AKELGATYLELHSLDDFYIGKYFGGVLEYFMIQALNQKTSEKMKKRKMSNSFHGIRPPQL
::::::::::::::::::::::::::::::
XP_016 MIQALNQKTSEKMKKRKMSNSFHGIRPPQL
10 20 30
230 240 250 260 270 280
pF1KA0 EQPEKMPVLKAEASHYNSDLNNLLFCCQCVDVVFYNPDLKKVVEAHKIVLCAVSHVFMLL
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
XP_016 EQPEKMPVLKAEASHYNSDLNNLLFCCQCVDVVFYNPNLKKVVEAHKIVLCAVSHVFMLL
40 50 60 70 80 90
290 300 310 320 330 340
pF1KA0 FNVKSPTDIQDSSIIRTTQDLFAINRDTAFPGASHESSGNPPLRVIVKDALFCSCLSDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNVKSPTDIQDSSIIRTTQDLFAINRDTAFPGASHESSGNPPLRVIVKDALFCSCLSDIL
100 110 120 130 140 150
350 360 370 380 390 400
pF1KA0 RFIYSGAFQWEELEEDIRKKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFIYSGAFQWEELEEDIRKKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLW
160 170 180 190 200 210
410 420 430 440 450 460
pF1KA0 FYNTSLKFFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYNTSLKFFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVY
220 230 240 250 260 270
470 480 490 500 510 520
pF1KA0 GVSKETFLSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVSKETFLSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSR
280 290 300 310 320 330
530 540 550 560 570 580
pF1KA0 ELASMNLDIVDLLKKAKFHHSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERSFVEKHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELASMNLDIVDLLKKAKFHHSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERSFVEKHR
340 350 360 370 380 390
590 600 610
pF1KA0 WPSNMYLKQLAEYRKYIHSRKCRCLVM
:::::::::::::::::::::::::::
XP_016 WPSNMYLKQLAEYRKYIHSRKCRCLVM
400 410
>>XP_016864725 (OMIM: 607353) PREDICTED: rho-related BTB (417 aa)
initn: 2808 init1: 2808 opt: 2808 Z-score: 3245.3 bits: 610.0 E(85289): 5e-174
Smith-Waterman score: 2808; 99.8% identity (100.0% similar) in 417 aa overlap (195-611:1-417)
170 180 190 200 210 220
pF1KA0 AKELGATYLELHSLDDFYIGKYFGGVLEYFMIQALNQKTSEKMKKRKMSNSFHGIRPPQL
::::::::::::::::::::::::::::::
XP_016 MIQALNQKTSEKMKKRKMSNSFHGIRPPQL
10 20 30
230 240 250 260 270 280
pF1KA0 EQPEKMPVLKAEASHYNSDLNNLLFCCQCVDVVFYNPDLKKVVEAHKIVLCAVSHVFMLL
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
XP_016 EQPEKMPVLKAEASHYNSDLNNLLFCCQCVDVVFYNPNLKKVVEAHKIVLCAVSHVFMLL
40 50 60 70 80 90
290 300 310 320 330 340
pF1KA0 FNVKSPTDIQDSSIIRTTQDLFAINRDTAFPGASHESSGNPPLRVIVKDALFCSCLSDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNVKSPTDIQDSSIIRTTQDLFAINRDTAFPGASHESSGNPPLRVIVKDALFCSCLSDIL
100 110 120 130 140 150
350 360 370 380 390 400
pF1KA0 RFIYSGAFQWEELEEDIRKKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFIYSGAFQWEELEEDIRKKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLW
160 170 180 190 200 210
410 420 430 440 450 460
pF1KA0 FYNTSLKFFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYNTSLKFFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVY
220 230 240 250 260 270
470 480 490 500 510 520
pF1KA0 GVSKETFLSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVSKETFLSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSR
280 290 300 310 320 330
530 540 550 560 570 580
pF1KA0 ELASMNLDIVDLLKKAKFHHSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERSFVEKHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELASMNLDIVDLLKKAKFHHSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERSFVEKHR
340 350 360 370 380 390
590 600 610
pF1KA0 WPSNMYLKQLAEYRKYIHSRKCRCLVM
:::::::::::::::::::::::::::
XP_016 WPSNMYLKQLAEYRKYIHSRKCRCLVM
400 410
>>XP_011541581 (OMIM: 607353) PREDICTED: rho-related BTB (489 aa)
initn: 3279 init1: 1777 opt: 1777 Z-score: 2053.7 bits: 389.8 E(85289): 1.2e-107
Smith-Waterman score: 3039; 80.0% identity (80.0% similar) in 611 aa overlap (1-611:1-489)
10 20 30 40 50 60
pF1KA0 MSIHIVALGNEGDTFHQDNRPSGLIRTYLGRSPLVSGDESSLLLNAASTVARPVFTEYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSIHIVALGNEGDTFHQDNRPSGLIRTYLGRSPLVSGDESSLLLNAASTVARPVFTEYQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SAFGNVKLVVHDCPVWDIFDSDWYTSRNLIGGADIIVIKYNVNDKFSFHEVKDNYIPVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAFGNVKLVVHDCPVWDIFDSDWYTSRNLIGGADIIVIKYNVNDKFSFHEVKDNYIPVIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RALNSVPVIIAAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALNSVPVIIAAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FYIGKYFGGVLEYFMIQALNQKTSEKMKKRKMSNSFHGIRPPQLEQPEKMPVLKAEASHY
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYIGKYFGGVLEYFMIQALNQKTSEKMKKRKMSNSFHGIRPPQLEQP-------------
190 200 210 220
250 260 270 280 290 300
pF1KA0 NSDLNNLLFCCQCVDVVFYNPDLKKVVEAHKIVLCAVSHVFMLLFNVKSPTDIQDSSIIR
XP_011 ------------------------------------------------------------
310 320 330 340 350 360
pF1KA0 TTQDLFAINRDTAFPGASHESSGNPPLRVIVKDALFCSCLSDILRFIYSGAFQWEELEED
:::::::::::
XP_011 -------------------------------------------------GAFQWEELEED
230
370 380 390 400 410 420
pF1KA0 IRKKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLWFYNTSLKFFLNKPMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRKKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLWFYNTSLKFFLNKPMLA
240 250 260 270 280 290
430 440 450 460 470 480
pF1KA0 DVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETFLSFLEYLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETFLSFLEYLYT
300 310 320 330 340 350
490 500 510 520 530 540
pF1KA0 DSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNLDIVDLLKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNLDIVDLLKKA
360 370 380 390 400 410
550 560 570 580 590 600
pF1KA0 KFHHSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERSFVEKHRWPSNMYLKQLAEYRKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFHHSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERSFVEKHRWPSNMYLKQLAEYRKY
420 430 440 450 460 470
610
pF1KA0 IHSRKCRCLVM
:::::::::::
XP_011 IHSRKCRCLVM
480
>>XP_016872496 (OMIM: 607351) PREDICTED: rho-related BTB (576 aa)
initn: 368 init1: 159 opt: 370 Z-score: 428.0 bits: 89.2 E(85289): 4.2e-17
Smith-Waterman score: 397; 24.0% identity (53.0% similar) in 526 aa overlap (152-605:45-551)
130 140 150 160 170 180
pF1KA0 ALNSVPVIIAAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDDF
::. . .: ..::::: : : .:.:
XP_016 VILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSVFDQF
20 30 40 50 60 70
190 200 210 220 230
pF1KA0 YIGKYFGGVLEYFMIQALN----QKTSEKMKKRKMSNSFHGIR--PPQLEQPEKMPVLKA
: : .... .:. . .. .:..: .. : . :: .. :: .
XP_016 GIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKIPECPSMGTN
80 90 100 110 120 130
240 250 260 270 280 290
pF1KA0 EASHYNSDLNNLLFCCQCVDVVFYNPDLKKVVEAHKIVLCAVSHVFMLLFNVK---SPT-
::. :.: : :.::.: : ... ::.: : . : :. :: .. ::.
XP_016 EAACL---LDNPL----CADVLFILQDQEHIF-AHRIYLATSSSKFYDLFLMECEESPNG
140 150 160 170 180
300
pF1KA0 ------------DIQ----------------------------DSSIIRT----------
:.: ..:....
XP_016 SEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLEAEGAVP
190 200 210 220 230 240
310 320 330 340 350
pF1KA0 -TQDLFAINRDTAFPGASHESSGNP------PLRVIVKDALFCSC-LSDILRFIYSGAFQ
:: : . .. .: : .: . :: :. :. :: . .:.:.:.: :
XP_016 ETQTLTGWSK--GFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYTG--Q
250 260 270 280 290 300
360 370 380 390 400 410
pF1KA0 WEELEEDIR--KKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLWFYNTSLK
.: :.:. .. . .. .. :. :.. . .: . :....:: . .:
XP_016 LDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMN-QEITKAFHVRK-----ANRIK
310 320 330 340 350
420 430 440 450 460 470
pF1KA0 FFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETF
:.: ..::.:... .. ::. .:. :: :::::.:...:. . . . ...: ..
XP_016 ECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISM
360 370 380 390 400 410
480 490 500 510 520 530
pF1KA0 LSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNL
. :.:::: . : .. . :. :. . . .: . : . .: . . .. ..
XP_016 QAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGVG-IDG
420 430 440 450 460 470
540 550 560 570 580
pF1KA0 DIVDLLKKAKFHHSDCLSTWLLHFIATNY-LIFSQ-KPEFQDLSVEERSFVEKHRWPSNM
.... :. :.::.. :..: :: : ::: . :. . :... :.... . :.::::
XP_016 EVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVW
480 490 500 510 520 530
590 600 610
pF1KA0 YLKQLAEYRKYIHSRKCRCLVM
:::. .:.. . :.
XP_016 YLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNSSPAVA
540 550 560 570
>>XP_016872494 (OMIM: 607351) PREDICTED: rho-related BTB (576 aa)
initn: 368 init1: 159 opt: 370 Z-score: 428.0 bits: 89.2 E(85289): 4.2e-17
Smith-Waterman score: 397; 24.0% identity (53.0% similar) in 526 aa overlap (152-605:45-551)
130 140 150 160 170 180
pF1KA0 ALNSVPVIIAAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDDF
::. . .: ..::::: : : .:.:
XP_016 VILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSVFDQF
20 30 40 50 60 70
190 200 210 220 230
pF1KA0 YIGKYFGGVLEYFMIQALN----QKTSEKMKKRKMSNSFHGIR--PPQLEQPEKMPVLKA
: : .... .:. . .. .:..: .. : . :: .. :: .
XP_016 GIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKIPECPSMGTN
80 90 100 110 120 130
240 250 260 270 280 290
pF1KA0 EASHYNSDLNNLLFCCQCVDVVFYNPDLKKVVEAHKIVLCAVSHVFMLLFNVK---SPT-
::. :.: : :.::.: : ... ::.: : . : :. :: .. ::.
XP_016 EAACL---LDNPL----CADVLFILQDQEHIF-AHRIYLATSSSKFYDLFLMECEESPNG
140 150 160 170 180
300
pF1KA0 ------------DIQ----------------------------DSSIIRT----------
:.: ..:....
XP_016 SEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLEAEGAVP
190 200 210 220 230 240
310 320 330 340 350
pF1KA0 -TQDLFAINRDTAFPGASHESSGNP------PLRVIVKDALFCSC-LSDILRFIYSGAFQ
:: : . .. .: : .: . :: :. :. :: . .:.:.:.: :
XP_016 ETQTLTGWSK--GFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYTG--Q
250 260 270 280 290 300
360 370 380 390 400 410
pF1KA0 WEELEEDIR--KKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLWFYNTSLK
.: :.:. .. . .. .. :. :.. . .: . :....:: . .:
XP_016 LDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMN-QEITKAFHVRK-----ANRIK
310 320 330 340 350
420 430 440 450 460 470
pF1KA0 FFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETF
:.: ..::.:... .. ::. .:. :: :::::.:...:. . . . ...: ..
XP_016 ECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISM
360 370 380 390 400 410
480 490 500 510 520 530
pF1KA0 LSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNL
. :.:::: . : .. . :. :. . . .: . : . .: . . .. ..
XP_016 QAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGVG-IDG
420 430 440 450 460 470
540 550 560 570 580
pF1KA0 DIVDLLKKAKFHHSDCLSTWLLHFIATNY-LIFSQ-KPEFQDLSVEERSFVEKHRWPSNM
.... :. :.::.. :..: :: : ::: . :. . :... :.... . :.::::
XP_016 EVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVW
480 490 500 510 520 530
590 600 610
pF1KA0 YLKQLAEYRKYIHSRKCRCLVM
:::. .:.. . :.
XP_016 YLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNSSPAVA
540 550 560 570
>>XP_016872495 (OMIM: 607351) PREDICTED: rho-related BTB (576 aa)
initn: 368 init1: 159 opt: 370 Z-score: 428.0 bits: 89.2 E(85289): 4.2e-17
Smith-Waterman score: 397; 24.0% identity (53.0% similar) in 526 aa overlap (152-605:45-551)
130 140 150 160 170 180
pF1KA0 ALNSVPVIIAAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDDF
::. . .: ..::::: : : .:.:
XP_016 VILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSVFDQF
20 30 40 50 60 70
190 200 210 220 230
pF1KA0 YIGKYFGGVLEYFMIQALN----QKTSEKMKKRKMSNSFHGIR--PPQLEQPEKMPVLKA
: : .... .:. . .. .:..: .. : . :: .. :: .
XP_016 GIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKIPECPSMGTN
80 90 100 110 120 130
240 250 260 270 280 290
pF1KA0 EASHYNSDLNNLLFCCQCVDVVFYNPDLKKVVEAHKIVLCAVSHVFMLLFNVK---SPT-
::. :.: : :.::.: : ... ::.: : . : :. :: .. ::.
XP_016 EAACL---LDNPL----CADVLFILQDQEHIF-AHRIYLATSSSKFYDLFLMECEESPNG
140 150 160 170 180
300
pF1KA0 ------------DIQ----------------------------DSSIIRT----------
:.: ..:....
XP_016 SEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLEAEGAVP
190 200 210 220 230 240
310 320 330 340 350
pF1KA0 -TQDLFAINRDTAFPGASHESSGNP------PLRVIVKDALFCSC-LSDILRFIYSGAFQ
:: : . .. .: : .: . :: :. :. :: . .:.:.:.: :
XP_016 ETQTLTGWSK--GFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYTG--Q
250 260 270 280 290 300
360 370 380 390 400 410
pF1KA0 WEELEEDIR--KKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLWFYNTSLK
.: :.:. .. . .. .. :. :.. . .: . :....:: . .:
XP_016 LDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMN-QEITKAFHVRK-----ANRIK
310 320 330 340 350
420 430 440 450 460 470
pF1KA0 FFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETF
:.: ..::.:... .. ::. .:. :: :::::.:...:. . . . ...: ..
XP_016 ECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISM
360 370 380 390 400 410
480 490 500 510 520 530
pF1KA0 LSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNL
. :.:::: . : .. . :. :. . . .: . : . .: . . .. ..
XP_016 QAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGVG-IDG
420 430 440 450 460 470
540 550 560 570 580
pF1KA0 DIVDLLKKAKFHHSDCLSTWLLHFIATNY-LIFSQ-KPEFQDLSVEERSFVEKHRWPSNM
.... :. :.::.. :..: :: : ::: . :. . :... :.... . :.::::
XP_016 EVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVW
480 490 500 510 520 530
590 600 610
pF1KA0 YLKQLAEYRKYIHSRKCRCLVM
:::. .:.. . :.
XP_016 YLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNSSPAVA
540 550 560 570
>>XP_016872497 (OMIM: 607351) PREDICTED: rho-related BTB (576 aa)
initn: 368 init1: 159 opt: 370 Z-score: 428.0 bits: 89.2 E(85289): 4.2e-17
Smith-Waterman score: 397; 24.0% identity (53.0% similar) in 526 aa overlap (152-605:45-551)
130 140 150 160 170 180
pF1KA0 ALNSVPVIIAAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDDF
::. . .: ..::::: : : .:.:
XP_016 VILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSVFDQF
20 30 40 50 60 70
190 200 210 220 230
pF1KA0 YIGKYFGGVLEYFMIQALN----QKTSEKMKKRKMSNSFHGIR--PPQLEQPEKMPVLKA
: : .... .:. . .. .:..: .. : . :: .. :: .
XP_016 GIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKIPECPSMGTN
80 90 100 110 120 130
240 250 260 270 280 290
pF1KA0 EASHYNSDLNNLLFCCQCVDVVFYNPDLKKVVEAHKIVLCAVSHVFMLLFNVK---SPT-
::. :.: : :.::.: : ... ::.: : . : :. :: .. ::.
XP_016 EAACL---LDNPL----CADVLFILQDQEHIF-AHRIYLATSSSKFYDLFLMECEESPNG
140 150 160 170 180
300
pF1KA0 ------------DIQ----------------------------DSSIIRT----------
:.: ..:....
XP_016 SEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLEAEGAVP
190 200 210 220 230 240
310 320 330 340 350
pF1KA0 -TQDLFAINRDTAFPGASHESSGNP------PLRVIVKDALFCSC-LSDILRFIYSGAFQ
:: : . .. .: : .: . :: :. :. :: . .:.:.:.: :
XP_016 ETQTLTGWSK--GFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYTG--Q
250 260 270 280 290 300
360 370 380 390 400 410
pF1KA0 WEELEEDIR--KKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLWFYNTSLK
.: :.:. .. . .. .. :. :.. . .: . :....:: . .:
XP_016 LDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMN-QEITKAFHVRK-----ANRIK
310 320 330 340 350
420 430 440 450 460 470
pF1KA0 FFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETF
:.: ..::.:... .. ::. .:. :: :::::.:...:. . . . ...: ..
XP_016 ECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISM
360 370 380 390 400 410
480 490 500 510 520 530
pF1KA0 LSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNL
. :.:::: . : .. . :. :. . . .: . : . .: . . .. ..
XP_016 QAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGVG-IDG
420 430 440 450 460 470
540 550 560 570 580
pF1KA0 DIVDLLKKAKFHHSDCLSTWLLHFIATNY-LIFSQ-KPEFQDLSVEERSFVEKHRWPSNM
.... :. :.::.. :..: :: : ::: . :. . :... :.... . :.::::
XP_016 EVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVW
480 490 500 510 520 530
590 600 610
pF1KA0 YLKQLAEYRKYIHSRKCRCLVM
:::. .:.. . :.
XP_016 YLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNSSPAVA
540 550 560 570
>>XP_016872492 (OMIM: 607351) PREDICTED: rho-related BTB (576 aa)
initn: 368 init1: 159 opt: 370 Z-score: 428.0 bits: 89.2 E(85289): 4.2e-17
Smith-Waterman score: 397; 24.0% identity (53.0% similar) in 526 aa overlap (152-605:45-551)
130 140 150 160 170 180
pF1KA0 ALNSVPVIIAAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDDF
::. . .: ..::::: : : .:.:
XP_016 VILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSVFDQF
20 30 40 50 60 70
190 200 210 220 230
pF1KA0 YIGKYFGGVLEYFMIQALN----QKTSEKMKKRKMSNSFHGIR--PPQLEQPEKMPVLKA
: : .... .:. . .. .:..: .. : . :: .. :: .
XP_016 GIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKIPECPSMGTN
80 90 100 110 120 130
240 250 260 270 280 290
pF1KA0 EASHYNSDLNNLLFCCQCVDVVFYNPDLKKVVEAHKIVLCAVSHVFMLLFNVK---SPT-
::. :.: : :.::.: : ... ::.: : . : :. :: .. ::.
XP_016 EAACL---LDNPL----CADVLFILQDQEHIF-AHRIYLATSSSKFYDLFLMECEESPNG
140 150 160 170 180
300
pF1KA0 ------------DIQ----------------------------DSSIIRT----------
:.: ..:....
XP_016 SEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLEAEGAVP
190 200 210 220 230 240
310 320 330 340 350
pF1KA0 -TQDLFAINRDTAFPGASHESSGNP------PLRVIVKDALFCSC-LSDILRFIYSGAFQ
:: : . .. .: : .: . :: :. :. :: . .:.:.:.: :
XP_016 ETQTLTGWSK--GFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYTG--Q
250 260 270 280 290 300
360 370 380 390 400 410
pF1KA0 WEELEEDIR--KKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLWFYNTSLK
.: :.:. .. . .. .. :. :.. . .: . :....:: . .:
XP_016 LDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMN-QEITKAFHVRK-----ANRIK
310 320 330 340 350
420 430 440 450 460 470
pF1KA0 FFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETF
:.: ..::.:... .. ::. .:. :: :::::.:...:. . . . ...: ..
XP_016 ECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISM
360 370 380 390 400 410
480 490 500 510 520 530
pF1KA0 LSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNL
. :.:::: . : .. . :. :. . . .: . : . .: . . .. ..
XP_016 QAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGVG-IDG
420 430 440 450 460 470
540 550 560 570 580
pF1KA0 DIVDLLKKAKFHHSDCLSTWLLHFIATNY-LIFSQ-KPEFQDLSVEERSFVEKHRWPSNM
.... :. :.::.. :..: :: : ::: . :. . :... :.... . :.::::
XP_016 EVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVW
480 490 500 510 520 530
590 600 610
pF1KA0 YLKQLAEYRKYIHSRKCRCLVM
:::. .:.. . :.
XP_016 YLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNSSPAVA
540 550 560 570
>>XP_016872493 (OMIM: 607351) PREDICTED: rho-related BTB (576 aa)
initn: 368 init1: 159 opt: 370 Z-score: 428.0 bits: 89.2 E(85289): 4.2e-17
Smith-Waterman score: 397; 24.0% identity (53.0% similar) in 526 aa overlap (152-605:45-551)
130 140 150 160 170 180
pF1KA0 ALNSVPVIIAAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDDF
::. . .: ..::::: : : .:.:
XP_016 VILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSVFDQF
20 30 40 50 60 70
190 200 210 220 230
pF1KA0 YIGKYFGGVLEYFMIQALN----QKTSEKMKKRKMSNSFHGIR--PPQLEQPEKMPVLKA
: : .... .:. . .. .:..: .. : . :: .. :: .
XP_016 GIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKIPECPSMGTN
80 90 100 110 120 130
240 250 260 270 280 290
pF1KA0 EASHYNSDLNNLLFCCQCVDVVFYNPDLKKVVEAHKIVLCAVSHVFMLLFNVK---SPT-
::. :.: : :.::.: : ... ::.: : . : :. :: .. ::.
XP_016 EAACL---LDNPL----CADVLFILQDQEHIF-AHRIYLATSSSKFYDLFLMECEESPNG
140 150 160 170 180
300
pF1KA0 ------------DIQ----------------------------DSSIIRT----------
:.: ..:....
XP_016 SEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLEAEGAVP
190 200 210 220 230 240
310 320 330 340 350
pF1KA0 -TQDLFAINRDTAFPGASHESSGNP------PLRVIVKDALFCSC-LSDILRFIYSGAFQ
:: : . .. .: : .: . :: :. :. :: . .:.:.:.: :
XP_016 ETQTLTGWSK--GFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYTG--Q
250 260 270 280 290 300
360 370 380 390 400 410
pF1KA0 WEELEEDIR--KKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLWFYNTSLK
.: :.:. .. . .. .. :. :.. . .: . :....:: . .:
XP_016 LDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMN-QEITKAFHVRK-----ANRIK
310 320 330 340 350
420 430 440 450 460 470
pF1KA0 FFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETF
:.: ..::.:... .. ::. .:. :: :::::.:...:. . . . ...: ..
XP_016 ECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISM
360 370 380 390 400 410
480 490 500 510 520 530
pF1KA0 LSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNL
. :.:::: . : .. . :. :. . . .: . : . .: . . .. ..
XP_016 QAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGVG-IDG
420 430 440 450 460 470
540 550 560 570 580
pF1KA0 DIVDLLKKAKFHHSDCLSTWLLHFIATNY-LIFSQ-KPEFQDLSVEERSFVEKHRWPSNM
.... :. :.::.. :..: :: : ::: . :. . :... :.... . :.::::
XP_016 EVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVW
480 490 500 510 520 530
590 600 610
pF1KA0 YLKQLAEYRKYIHSRKCRCLVM
:::. .:.. . :.
XP_016 YLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNSSPAVA
540 550 560 570
611 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:53:22 2016 done: Wed Nov 2 19:53:24 2016
Total Scan time: 8.270 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]