Result of FASTA (omim) for
pF1KA0896
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0896, 2798 aa
1>>>pF1KA0896 2798 - 2798 aa - 2798 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2881+/-0.000436; mu= 13.4612+/- 0.027
mean_var=190.9800+/-38.776, 0's: 0 Z-trim(117.7): 287 B-trim: 1084 in 1/54
Lambda= 0.092807
statistics sampled from 29640 (29964) to 29640 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.351), width: 16
Scan time: 22.540
The best scores are: opt bits E(85289)
NP_001269802 (OMIM: 608413) E3 ubiquitin-protein l (2798) 18532 2495.9 0
NP_056986 (OMIM: 608413) E3 ubiquitin-protein liga (2799) 18520 2494.3 0
XP_016869023 (OMIM: 608413) PREDICTED: E3 ubiquiti (2783) 18303 2465.3 0
XP_016869022 (OMIM: 608413) PREDICTED: E3 ubiquiti (2784) 18291 2463.7 0
XP_011515407 (OMIM: 608413) PREDICTED: E3 ubiquiti (2785) 18289 2463.4 0
XP_011515406 (OMIM: 608413) PREDICTED: E3 ubiquiti (2786) 18277 2461.8 0
XP_011515408 (OMIM: 608413) PREDICTED: E3 ubiquiti (2780) 18220 2454.1 0
XP_005251019 (OMIM: 608413) PREDICTED: E3 ubiquiti (1811) 11955 1615.2 0
XP_016866611 (OMIM: 610876,616756) PREDICTED: E3 u ( 715) 420 70.4 1.1e-10
XP_016866610 (OMIM: 610876,616756) PREDICTED: E3 u ( 715) 420 70.4 1.1e-10
XP_016866609 (OMIM: 610876,616756) PREDICTED: E3 u ( 741) 420 70.4 1.1e-10
XP_016866608 (OMIM: 610876,616756) PREDICTED: E3 u ( 741) 420 70.4 1.1e-10
XP_016866607 (OMIM: 610876,616756) PREDICTED: E3 u ( 741) 420 70.4 1.1e-10
NP_001308013 (OMIM: 610876,616756) E3 ubiquitin-pr ( 741) 420 70.4 1.1e-10
XP_016866605 (OMIM: 610876,616756) PREDICTED: E3 u ( 741) 420 70.4 1.1e-10
XP_016866604 (OMIM: 610876,616756) PREDICTED: E3 u ( 747) 420 70.4 1.1e-10
XP_016866603 (OMIM: 610876,616756) PREDICTED: E3 u ( 831) 420 70.5 1.2e-10
XP_016866602 (OMIM: 610876,616756) PREDICTED: E3 u ( 831) 420 70.5 1.2e-10
NP_001308009 (OMIM: 610876,616756) E3 ubiquitin-pr ( 865) 420 70.5 1.3e-10
NP_001308012 (OMIM: 610876,616756) E3 ubiquitin-pr ( 875) 420 70.5 1.3e-10
NP_065822 (OMIM: 610876,616756) E3 ubiquitin-prote ( 909) 420 70.5 1.3e-10
XP_011535719 (OMIM: 615380) PREDICTED: apoptosis-r ( 662) 385 65.7 2.6e-09
XP_005268301 (OMIM: 615380) PREDICTED: apoptosis-r ( 662) 385 65.7 2.6e-09
XP_006720407 (OMIM: 615380) PREDICTED: apoptosis-r ( 813) 385 65.8 3.1e-09
XP_011535717 (OMIM: 615380) PREDICTED: apoptosis-r ( 823) 385 65.8 3.1e-09
NP_001034568 (OMIM: 615380) apoptosis-resistant E3 ( 823) 385 65.8 3.1e-09
XP_016884695 (OMIM: 300697,300706) PREDICTED: E3 u (4367) 395 67.7 4.4e-09
XP_005262022 (OMIM: 300697,300706) PREDICTED: E3 u (4374) 395 67.7 4.4e-09
NP_113584 (OMIM: 300697,300706) E3 ubiquitin-prote (4374) 395 67.7 4.4e-09
XP_016884694 (OMIM: 300697,300706) PREDICTED: E3 u (4377) 395 67.7 4.5e-09
XP_016884693 (OMIM: 300697,300706) PREDICTED: E3 u (4418) 395 67.7 4.5e-09
XP_011529053 (OMIM: 300697,300706) PREDICTED: E3 u (4457) 395 67.7 4.5e-09
XP_011529049 (OMIM: 300697,300706) PREDICTED: E3 u (4457) 395 67.7 4.5e-09
XP_016884688 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 395 67.7 4.5e-09
XP_016884687 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 395 67.7 4.5e-09
XP_016884689 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 395 67.7 4.5e-09
XP_016884690 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 395 67.7 4.5e-09
XP_016884692 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 395 67.7 4.5e-09
XP_016884691 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 395 67.7 4.5e-09
XP_016884686 (OMIM: 300697,300706) PREDICTED: E3 u (4468) 395 67.7 4.5e-09
XP_016884685 (OMIM: 300697,300706) PREDICTED: E3 u (4484) 395 67.7 4.5e-09
XP_016884684 (OMIM: 300697,300706) PREDICTED: E3 u (4485) 395 67.7 4.5e-09
XP_016884683 (OMIM: 300697,300706) PREDICTED: E3 u (4486) 395 67.7 4.5e-09
XP_016884682 (OMIM: 300697,300706) PREDICTED: E3 u (4494) 395 67.7 4.5e-09
XP_016884681 (OMIM: 300697,300706) PREDICTED: E3 u (4500) 395 67.7 4.5e-09
XP_016884680 (OMIM: 300697,300706) PREDICTED: E3 u (4501) 395 67.7 4.5e-09
XP_005257642 (OMIM: 605532) PREDICTED: E3 ubiquiti ( 735) 375 64.4 7.2e-09
NP_073576 (OMIM: 605532) E3 ubiquitin-protein liga ( 748) 375 64.4 7.3e-09
XP_011523430 (OMIM: 605532) PREDICTED: E3 ubiquiti ( 750) 375 64.4 7.3e-09
NP_001186776 (OMIM: 605568) E3 ubiquitin-protein l ( 728) 372 64.0 9.5e-09
>>NP_001269802 (OMIM: 608413) E3 ubiquitin-protein ligas (2798 aa)
initn: 18532 init1: 18532 opt: 18532 Z-score: 13410.8 bits: 2495.9 E(85289): 0
Smith-Waterman score: 18532; 100.0% identity (100.0% similar) in 2798 aa overlap (1-2798:1-2798)
10 20 30 40 50 60
pF1KA0 MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA0 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KA0 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KA0 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KA0 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KA0 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KA0 KESKFRREMEKLRNQQSRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KESKFRREMEKLRNQQSRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVT
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KA0 FKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDRER
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KA0 EREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGER
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KA0 LYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADS
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KA0 ILDLGLVDSSEKVQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILDLGLVDSSEKVQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKN
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KA0 TEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQ
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KA0 LILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEH
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KA0 RMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESG
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KA0 ENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQH
2710 2720 2730 2740 2750 2760
2770 2780 2790
pF1KA0 LPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
::::::::::::::::::::::::::::::::::::::
NP_001 LPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
2770 2780 2790
>>NP_056986 (OMIM: 608413) E3 ubiquitin-protein ligase U (2799 aa)
initn: 16360 init1: 16360 opt: 18520 Z-score: 13402.1 bits: 2494.3 E(85289): 0
Smith-Waterman score: 18520; 100.0% identity (100.0% similar) in 2799 aa overlap (1-2798:1-2799)
10 20 30 40 50 60
pF1KA0 MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA0 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KA0 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KA0 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KA0 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KA0 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KA0 KESKFRREMEKLRNQQSRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KESKFRREMEKLRNQQSRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVT
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KA0 FKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDRER
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KA0 EREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGER
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KA0 LYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADS
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510
pF1KA0 ILDLGLVDSSEKVQ-ENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGK
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
NP_056 ILDLGLVDSSEKVQQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGK
2470 2480 2490 2500 2510 2520
2520 2530 2540 2550 2560 2570
pF1KA0 NTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLR
2530 2540 2550 2560 2570 2580
2580 2590 2600 2610 2620 2630
pF1KA0 QLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAE
2590 2600 2610 2620 2630 2640
2640 2650 2660 2670 2680 2690
pF1KA0 HRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDES
2650 2660 2670 2680 2690 2700
2700 2710 2720 2730 2740 2750
pF1KA0 GENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ
2710 2720 2730 2740 2750 2760
2760 2770 2780 2790
pF1KA0 HLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
:::::::::::::::::::::::::::::::::::::::
NP_056 HLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
2770 2780 2790
>>XP_016869023 (OMIM: 608413) PREDICTED: E3 ubiquitin-pr (2783 aa)
initn: 18303 init1: 18303 opt: 18303 Z-score: 13245.1 bits: 2465.3 E(85289): 0
Smith-Waterman score: 18400; 99.5% identity (99.5% similar) in 2798 aa overlap (1-2798:1-2783)
10 20 30 40 50 60
pF1KA0 MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
:::::::::::::::::::: :::::::::::::::::::::::::
XP_016 MTSIHFVVHPLPGTEDQLND---------------SHPPLNVLEQATIKQCVVGPNHAAF
10 20 30 40
70 80 90 100 110 120
pF1KA0 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
350 360 370 380 390 400
430 440 450 460 470 480
pF1KA0 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
410 420 430 440 450 460
490 500 510 520 530 540
pF1KA0 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
470 480 490 500 510 520
550 560 570 580 590 600
pF1KA0 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
530 540 550 560 570 580
610 620 630 640 650 660
pF1KA0 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
590 600 610 620 630 640
670 680 690 700 710 720
pF1KA0 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
650 660 670 680 690 700
730 740 750 760 770 780
pF1KA0 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
710 720 730 740 750 760
790 800 810 820 830 840
pF1KA0 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KA0 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
830 840 850 860 870 880
910 920 930 940 950 960
pF1KA0 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KA0 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KA0 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KA0 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KA0 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KA0 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KA0 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KA0 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KA0 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KA0 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KA0 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
pF1KA0 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KA0 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KA0 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KA0 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KA0 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KA0 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KA0 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
1910 1920 1930 1940 1950 1960
1990 2000 2010 2020 2030 2040
pF1KA0 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
1970 1980 1990 2000 2010 2020
2050 2060 2070 2080 2090 2100
pF1KA0 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
2030 2040 2050 2060 2070 2080
2110 2120 2130 2140 2150 2160
pF1KA0 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
2090 2100 2110 2120 2130 2140
2170 2180 2190 2200 2210 2220
pF1KA0 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
2150 2160 2170 2180 2190 2200
2230 2240 2250 2260 2270 2280
pF1KA0 KESKFRREMEKLRNQQSRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KESKFRREMEKLRNQQSRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVT
2210 2220 2230 2240 2250 2260
2290 2300 2310 2320 2330 2340
pF1KA0 FKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDRER
2270 2280 2290 2300 2310 2320
2350 2360 2370 2380 2390 2400
pF1KA0 EREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGER
2330 2340 2350 2360 2370 2380
2410 2420 2430 2440 2450 2460
pF1KA0 LYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADS
2390 2400 2410 2420 2430 2440
2470 2480 2490 2500 2510 2520
pF1KA0 ILDLGLVDSSEKVQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILDLGLVDSSEKVQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKN
2450 2460 2470 2480 2490 2500
2530 2540 2550 2560 2570 2580
pF1KA0 TEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQ
2510 2520 2530 2540 2550 2560
2590 2600 2610 2620 2630 2640
pF1KA0 LILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEH
2570 2580 2590 2600 2610 2620
2650 2660 2670 2680 2690 2700
pF1KA0 RMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESG
2630 2640 2650 2660 2670 2680
2710 2720 2730 2740 2750 2760
pF1KA0 ENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQH
2690 2700 2710 2720 2730 2740
2770 2780 2790
pF1KA0 LPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
::::::::::::::::::::::::::::::::::::::
XP_016 LPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
2750 2760 2770 2780
>>XP_016869022 (OMIM: 608413) PREDICTED: E3 ubiquitin-pr (2784 aa)
initn: 16131 init1: 16131 opt: 18291 Z-score: 13236.4 bits: 2463.7 E(85289): 0
Smith-Waterman score: 18388; 99.4% identity (99.4% similar) in 2799 aa overlap (1-2798:1-2784)
10 20 30 40 50 60
pF1KA0 MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
:::::::::::::::::::: :::::::::::::::::::::::::
XP_016 MTSIHFVVHPLPGTEDQLND---------------SHPPLNVLEQATIKQCVVGPNHAAF
10 20 30 40
70 80 90 100 110 120
pF1KA0 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
350 360 370 380 390 400
430 440 450 460 470 480
pF1KA0 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
410 420 430 440 450 460
490 500 510 520 530 540
pF1KA0 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
470 480 490 500 510 520
550 560 570 580 590 600
pF1KA0 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
530 540 550 560 570 580
610 620 630 640 650 660
pF1KA0 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
590 600 610 620 630 640
670 680 690 700 710 720
pF1KA0 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
650 660 670 680 690 700
730 740 750 760 770 780
pF1KA0 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
710 720 730 740 750 760
790 800 810 820 830 840
pF1KA0 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KA0 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
830 840 850 860 870 880
910 920 930 940 950 960
pF1KA0 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KA0 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KA0 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KA0 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KA0 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KA0 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KA0 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KA0 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KA0 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KA0 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KA0 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
pF1KA0 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KA0 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KA0 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KA0 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KA0 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KA0 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KA0 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
1910 1920 1930 1940 1950 1960
1990 2000 2010 2020 2030 2040
pF1KA0 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
1970 1980 1990 2000 2010 2020
2050 2060 2070 2080 2090 2100
pF1KA0 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
2030 2040 2050 2060 2070 2080
2110 2120 2130 2140 2150 2160
pF1KA0 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
2090 2100 2110 2120 2130 2140
2170 2180 2190 2200 2210 2220
pF1KA0 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
2150 2160 2170 2180 2190 2200
2230 2240 2250 2260 2270 2280
pF1KA0 KESKFRREMEKLRNQQSRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KESKFRREMEKLRNQQSRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVT
2210 2220 2230 2240 2250 2260
2290 2300 2310 2320 2330 2340
pF1KA0 FKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDRER
2270 2280 2290 2300 2310 2320
2350 2360 2370 2380 2390 2400
pF1KA0 EREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGER
2330 2340 2350 2360 2370 2380
2410 2420 2430 2440 2450 2460
pF1KA0 LYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADS
2390 2400 2410 2420 2430 2440
2470 2480 2490 2500 2510
pF1KA0 ILDLGLVDSSEKVQ-ENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGK
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILDLGLVDSSEKVQQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGK
2450 2460 2470 2480 2490 2500
2520 2530 2540 2550 2560 2570
pF1KA0 NTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLR
2510 2520 2530 2540 2550 2560
2580 2590 2600 2610 2620 2630
pF1KA0 QLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAE
2570 2580 2590 2600 2610 2620
2640 2650 2660 2670 2680 2690
pF1KA0 HRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDES
2630 2640 2650 2660 2670 2680
2700 2710 2720 2730 2740 2750
pF1KA0 GENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ
2690 2700 2710 2720 2730 2740
2760 2770 2780 2790
pF1KA0 HLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
:::::::::::::::::::::::::::::::::::::::
XP_016 HLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
2750 2760 2770 2780
>>XP_011515407 (OMIM: 608413) PREDICTED: E3 ubiquitin-pr (2785 aa)
initn: 14676 init1: 14625 opt: 18289 Z-score: 13235.0 bits: 2463.4 E(85289): 0
Smith-Waterman score: 18386; 99.4% identity (99.4% similar) in 2800 aa overlap (1-2798:1-2785)
10 20 30 40 50 60
pF1KA0 MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
:::::::::::::::::::: :::::::::::::::::::::::::
XP_011 MTSIHFVVHPLPGTEDQLND---------------SHPPLNVLEQATIKQCVVGPNHAAF
10 20 30 40
70 80 90 100 110 120
pF1KA0 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
350 360 370 380 390 400
430 440 450 460 470 480
pF1KA0 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
410 420 430 440 450 460
490 500 510 520 530 540
pF1KA0 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
470 480 490 500 510 520
550 560 570 580 590 600
pF1KA0 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
530 540 550 560 570 580
610 620 630 640 650 660
pF1KA0 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
590 600 610 620 630 640
670 680 690 700 710 720
pF1KA0 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
650 660 670 680 690 700
730 740 750 760 770 780
pF1KA0 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
710 720 730 740 750 760
790 800 810 820 830 840
pF1KA0 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KA0 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
830 840 850 860 870 880
910 920 930 940 950 960
pF1KA0 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KA0 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KA0 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KA0 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KA0 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KA0 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KA0 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KA0 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KA0 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KA0 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KA0 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
pF1KA0 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KA0 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KA0 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KA0 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KA0 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KA0 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KA0 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
1910 1920 1930 1940 1950 1960
1990 2000 2010 2020 2030 2040
pF1KA0 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
1970 1980 1990 2000 2010 2020
2050 2060 2070 2080 2090 2100
pF1KA0 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
2030 2040 2050 2060 2070 2080
2110 2120 2130 2140 2150 2160
pF1KA0 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
2090 2100 2110 2120 2130 2140
2170 2180 2190 2200 2210 2220
pF1KA0 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
2150 2160 2170 2180 2190 2200
2230 2240 2250 2260 2270
pF1KA0 KESKFRREMEKLRNQQSRDLSLEV--DRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVK
:::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 KESKFRREMEKLRNQQSRDLSLEVKVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVK
2210 2220 2230 2240 2250 2260
2280 2290 2300 2310 2320 2330
pF1KA0 VTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDR
2270 2280 2290 2300 2310 2320
2340 2350 2360 2370 2380 2390
pF1KA0 EREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALG
2330 2340 2350 2360 2370 2380
2400 2410 2420 2430 2440 2450
pF1KA0 ERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGA
2390 2400 2410 2420 2430 2440
2460 2470 2480 2490 2500 2510
pF1KA0 DSILDLGLVDSSEKVQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSILDLGLVDSSEKVQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPG
2450 2460 2470 2480 2490 2500
2520 2530 2540 2550 2560 2570
pF1KA0 KNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESL
2510 2520 2530 2540 2550 2560
2580 2590 2600 2610 2620 2630
pF1KA0 RQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYA
2570 2580 2590 2600 2610 2620
2640 2650 2660 2670 2680 2690
pF1KA0 EHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDE
2630 2640 2650 2660 2670 2680
2700 2710 2720 2730 2740 2750
pF1KA0 SGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDD
2690 2700 2710 2720 2730 2740
2760 2770 2780 2790
pF1KA0 QHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
::::::::::::::::::::::::::::::::::::::::
XP_011 QHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
2750 2760 2770 2780
>>XP_011515406 (OMIM: 608413) PREDICTED: E3 ubiquitin-pr (2786 aa)
initn: 16854 init1: 14625 opt: 18277 Z-score: 13226.3 bits: 2461.8 E(85289): 0
Smith-Waterman score: 18374; 99.4% identity (99.4% similar) in 2801 aa overlap (1-2798:1-2786)
10 20 30 40 50 60
pF1KA0 MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
:::::::::::::::::::: :::::::::::::::::::::::::
XP_011 MTSIHFVVHPLPGTEDQLND---------------SHPPLNVLEQATIKQCVVGPNHAAF
10 20 30 40
70 80 90 100 110 120
pF1KA0 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
350 360 370 380 390 400
430 440 450 460 470 480
pF1KA0 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
410 420 430 440 450 460
490 500 510 520 530 540
pF1KA0 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
470 480 490 500 510 520
550 560 570 580 590 600
pF1KA0 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
530 540 550 560 570 580
610 620 630 640 650 660
pF1KA0 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
590 600 610 620 630 640
670 680 690 700 710 720
pF1KA0 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
650 660 670 680 690 700
730 740 750 760 770 780
pF1KA0 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
710 720 730 740 750 760
790 800 810 820 830 840
pF1KA0 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KA0 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
830 840 850 860 870 880
910 920 930 940 950 960
pF1KA0 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KA0 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KA0 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KA0 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KA0 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KA0 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KA0 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KA0 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KA0 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KA0 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KA0 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
pF1KA0 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KA0 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KA0 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KA0 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KA0 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KA0 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KA0 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
1910 1920 1930 1940 1950 1960
1990 2000 2010 2020 2030 2040
pF1KA0 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
1970 1980 1990 2000 2010 2020
2050 2060 2070 2080 2090 2100
pF1KA0 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
2030 2040 2050 2060 2070 2080
2110 2120 2130 2140 2150 2160
pF1KA0 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
2090 2100 2110 2120 2130 2140
2170 2180 2190 2200 2210 2220
pF1KA0 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
2150 2160 2170 2180 2190 2200
2230 2240 2250 2260 2270
pF1KA0 KESKFRREMEKLRNQQSRDLSLEV--DRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVK
:::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 KESKFRREMEKLRNQQSRDLSLEVKVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVK
2210 2220 2230 2240 2250 2260
2280 2290 2300 2310 2320 2330
pF1KA0 VTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDR
2270 2280 2290 2300 2310 2320
2340 2350 2360 2370 2380 2390
pF1KA0 EREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALG
2330 2340 2350 2360 2370 2380
2400 2410 2420 2430 2440 2450
pF1KA0 ERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGA
2390 2400 2410 2420 2430 2440
2460 2470 2480 2490 2500 2510
pF1KA0 DSILDLGLVDSSEKVQ-ENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRP
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_011 DSILDLGLVDSSEKVQQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRP
2450 2460 2470 2480 2490 2500
2520 2530 2540 2550 2560 2570
pF1KA0 GKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYES
2510 2520 2530 2540 2550 2560
2580 2590 2600 2610 2620 2630
pF1KA0 LRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKY
2570 2580 2590 2600 2610 2620
2640 2650 2660 2670 2680 2690
pF1KA0 AEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFND
2630 2640 2650 2660 2670 2680
2700 2710 2720 2730 2740 2750
pF1KA0 ESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPD
2690 2700 2710 2720 2730 2740
2760 2770 2780 2790
pF1KA0 DQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
:::::::::::::::::::::::::::::::::::::::::
XP_011 DQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
2750 2760 2770 2780
>>XP_011515408 (OMIM: 608413) PREDICTED: E3 ubiquitin-pr (2780 aa)
initn: 15227 init1: 12873 opt: 18220 Z-score: 13185.1 bits: 2454.1 E(85289): 0
Smith-Waterman score: 18317; 99.1% identity (99.1% similar) in 2801 aa overlap (1-2798:1-2780)
10 20 30 40 50 60
pF1KA0 MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
:::::::::::::::::::: :::::::::::::::::::::::::
XP_011 MTSIHFVVHPLPGTEDQLND---------------SHPPLNVLEQATIKQCVVGPNHAAF
10 20 30 40
70 80 90 100 110 120
pF1KA0 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSR-----
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -ERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
290 300 310 320 330
370 380 390 400 410 420
pF1KA0 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA0 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KA0 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KA0 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KA0 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KA0 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KA0 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KA0 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KA0 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480 1490 1500
pF1KA0 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KA0 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KA0 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KA0 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730 1740
pF1KA0 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
1660 1670 1680 1690 1700 1710
1750 1760 1770 1780 1790 1800
pF1KA0 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
1720 1730 1740 1750 1760 1770
1810 1820 1830 1840 1850 1860
pF1KA0 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
1780 1790 1800 1810 1820 1830
1870 1880 1890 1900 1910 1920
pF1KA0 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
1840 1850 1860 1870 1880 1890
1930 1940 1950 1960 1970 1980
pF1KA0 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
1900 1910 1920 1930 1940 1950
1990 2000 2010 2020 2030 2040
pF1KA0 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
1960 1970 1980 1990 2000 2010
2050 2060 2070 2080 2090 2100
pF1KA0 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
2020 2030 2040 2050 2060 2070
2110 2120 2130 2140 2150 2160
pF1KA0 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
2080 2090 2100 2110 2120 2130
2170 2180 2190 2200 2210 2220
pF1KA0 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
2140 2150 2160 2170 2180 2190
2230 2240 2250 2260 2270
pF1KA0 KESKFRREMEKLRNQQSRDLSLEV--DRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVK
:::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 KESKFRREMEKLRNQQSRDLSLEVKVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVK
2200 2210 2220 2230 2240 2250
2280 2290 2300 2310 2320 2330
pF1KA0 VTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDR
2260 2270 2280 2290 2300 2310
2340 2350 2360 2370 2380 2390
pF1KA0 EREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALG
2320 2330 2340 2350 2360 2370
2400 2410 2420 2430 2440 2450
pF1KA0 ERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGA
2380 2390 2400 2410 2420 2430
2460 2470 2480 2490 2500 2510
pF1KA0 DSILDLGLVDSSEKVQ-ENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRP
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_011 DSILDLGLVDSSEKVQQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRP
2440 2450 2460 2470 2480 2490
2520 2530 2540 2550 2560 2570
pF1KA0 GKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYES
2500 2510 2520 2530 2540 2550
2580 2590 2600 2610 2620 2630
pF1KA0 LRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKY
2560 2570 2580 2590 2600 2610
2640 2650 2660 2670 2680 2690
pF1KA0 AEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFND
2620 2630 2640 2650 2660 2670
2700 2710 2720 2730 2740 2750
pF1KA0 ESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPD
2680 2690 2700 2710 2720 2730
2760 2770 2780 2790
pF1KA0 DQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
:::::::::::::::::::::::::::::::::::::::::
XP_011 DQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
2740 2750 2760 2770 2780
>>XP_005251019 (OMIM: 608413) PREDICTED: E3 ubiquitin-pr (1811 aa)
initn: 10532 init1: 8303 opt: 11955 Z-score: 8654.2 bits: 1615.2 E(85289): 0
Smith-Waterman score: 11955; 99.8% identity (99.8% similar) in 1811 aa overlap (991-2798:1-1811)
970 980 990 1000 1010 1020
pF1KA0 AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
::::::::::::::::::::::::::::::
XP_005 MMRRSLRAAGLGRHEAGASSSDHQDPVSPP
10 20 30
1030 1040 1050 1060 1070 1080
pF1KA0 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
40 50 60 70 80 90
1090 1100 1110 1120 1130 1140
pF1KA0 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
100 110 120 130 140 150
1150 1160 1170 1180 1190 1200
pF1KA0 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
160 170 180 190 200 210
1210 1220 1230 1240 1250 1260
pF1KA0 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
220 230 240 250 260 270
1270 1280 1290 1300 1310 1320
pF1KA0 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
280 290 300 310 320 330
1330 1340 1350 1360 1370 1380
pF1KA0 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
340 350 360 370 380 390
1390 1400 1410 1420 1430 1440
pF1KA0 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
400 410 420 430 440 450
1450 1460 1470 1480 1490 1500
pF1KA0 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
460 470 480 490 500 510
1510 1520 1530 1540 1550 1560
pF1KA0 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
520 530 540 550 560 570
1570 1580 1590 1600 1610 1620
pF1KA0 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
580 590 600 610 620 630
1630 1640 1650 1660 1670 1680
pF1KA0 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
640 650 660 670 680 690
1690 1700 1710 1720 1730 1740
pF1KA0 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
700 710 720 730 740 750
1750 1760 1770 1780 1790 1800
pF1KA0 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
760 770 780 790 800 810
1810 1820 1830 1840 1850 1860
pF1KA0 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
820 830 840 850 860 870
1870 1880 1890 1900 1910 1920
pF1KA0 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
880 890 900 910 920 930
1930 1940 1950 1960 1970 1980
pF1KA0 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
940 950 960 970 980 990
1990 2000 2010 2020 2030 2040
pF1KA0 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
1000 1010 1020 1030 1040 1050
2050 2060 2070 2080 2090 2100
pF1KA0 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
1060 1070 1080 1090 1100 1110
2110 2120 2130 2140 2150 2160
pF1KA0 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
1120 1130 1140 1150 1160 1170
2170 2180 2190 2200 2210 2220
pF1KA0 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
1180 1190 1200 1210 1220 1230
2230 2240 2250 2260 2270
pF1KA0 KESKFRREMEKLRNQQSRDLSLEV--DRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVK
:::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_005 KESKFRREMEKLRNQQSRDLSLEVKVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVK
1240 1250 1260 1270 1280 1290
2280 2290 2300 2310 2320 2330
pF1KA0 VTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDR
1300 1310 1320 1330 1340 1350
2340 2350 2360 2370 2380 2390
pF1KA0 EREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALG
1360 1370 1380 1390 1400 1410
2400 2410 2420 2430 2440 2450
pF1KA0 ERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGA
1420 1430 1440 1450 1460 1470
2460 2470 2480 2490 2500 2510
pF1KA0 DSILDLGLVDSSEKVQ-ENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRP
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_005 DSILDLGLVDSSEKVQQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRP
1480 1490 1500 1510 1520 1530
2520 2530 2540 2550 2560 2570
pF1KA0 GKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYES
1540 1550 1560 1570 1580 1590
2580 2590 2600 2610 2620 2630
pF1KA0 LRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKY
1600 1610 1620 1630 1640 1650
2640 2650 2660 2670 2680 2690
pF1KA0 AEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFND
1660 1670 1680 1690 1700 1710
2700 2710 2720 2730 2740 2750
pF1KA0 ESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPD
1720 1730 1740 1750 1760 1770
2760 2770 2780 2790
pF1KA0 DQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
:::::::::::::::::::::::::::::::::::::::::
XP_005 DQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
1780 1790 1800 1810
>>XP_016866611 (OMIM: 610876,616756) PREDICTED: E3 ubiqu (715 aa)
initn: 337 init1: 126 opt: 420 Z-score: 312.9 bits: 70.4 E(85289): 1.1e-10
Smith-Waterman score: 421; 32.0% identity (61.0% similar) in 300 aa overlap (2505-2797:431-712)
2480 2490 2500 2510 2520 2530
pF1KA0 ENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRI
.::.. .. .: .:: :: :.:
XP_016 GVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNP-------DHLNYFRFAGQI
410 420 430 440 450
2540 2550 2560 2570 2580 2590
pF1KA0 LGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVF
::: : . .: : ..: : .:: ::..: : .:: . ..: : :: .. ::
XP_016 LGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNL-QWILDNDISDL----
460 470 480 490 500
2600 2610 2620 2630 2640 2650
pF1KA0 SAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMR
...:.:... . .: : :.: .: :: .: :::. .: :: . . ..:.
XP_016 -GLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFL
510 520 530 540 550 560
2660 2670 2680 2690 2700 2710
pF1KA0 KGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESG-ENAEKLLQFKRWF
.:. .: . .. . ...::..: :..:. :. : .. :: : . ..: ::
XP_016 QGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYT--SGYEREDPVIQ---WF
570 580 590 600 610 620
2720 2730 2740 2750 2760
pF1KA0 WSIVEKMSMTERQDLVYFWTSSPSLP----ASEEGFQPMPSITIR--PPDDQHLPTANTC
: .:: ... :: :. : :.: .: :. : . . ..:: : . :::..::
XP_016 WEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTC
630 640 650 660 670 680
2770 2780 2790
pF1KA0 ISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
:. : .: : ::.:::..::.:.. ..:.
XP_016 INMLKLPEYPSKEILKDRLLVALHCGSYGYTMA
690 700 710
>>XP_016866610 (OMIM: 610876,616756) PREDICTED: E3 ubiqu (715 aa)
initn: 337 init1: 126 opt: 420 Z-score: 312.9 bits: 70.4 E(85289): 1.1e-10
Smith-Waterman score: 421; 32.0% identity (61.0% similar) in 300 aa overlap (2505-2797:431-712)
2480 2490 2500 2510 2520 2530
pF1KA0 ENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRI
.::.. .. .: .:: :: :.:
XP_016 GVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNP-------DHLNYFRFAGQI
410 420 430 440 450
2540 2550 2560 2570 2580 2590
pF1KA0 LGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVF
::: : . .: : ..: : .:: ::..: : .:: . ..: : :: .. ::
XP_016 LGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNL-QWILDNDISDL----
460 470 480 490 500
2600 2610 2620 2630 2640 2650
pF1KA0 SAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMR
...:.:... . .: : :.: .: :: .: :::. .: :: . . ..:.
XP_016 -GLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFL
510 520 530 540 550 560
2660 2670 2680 2690 2700 2710
pF1KA0 KGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESG-ENAEKLLQFKRWF
.:. .: . .. . ...::..: :..:. :. : .. :: : . ..: ::
XP_016 QGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYT--SGYEREDPVIQ---WF
570 580 590 600 610 620
2720 2730 2740 2750 2760
pF1KA0 WSIVEKMSMTERQDLVYFWTSSPSLP----ASEEGFQPMPSITIR--PPDDQHLPTANTC
: .:: ... :: :. : :.: .: :. : . . ..:: : . :::..::
XP_016 WEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTC
630 640 650 660 670 680
2770 2780 2790
pF1KA0 ISRLYVPLYSSKQILKQKLLLAIKTKNFGFV
:. : .: : ::.:::..::.:.. ..:.
XP_016 INMLKLPEYPSKEILKDRLLVALHCGSYGYTMA
690 700 710
2798 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:51:03 2016 done: Thu Nov 3 19:51:06 2016
Total Scan time: 22.540 Total Display time: 1.990
Function used was FASTA [36.3.4 Apr, 2011]