FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0900, 502 aa 1>>>pF1KA0900 502 - 502 aa - 502 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.3705+/-0.0012; mu= -18.4021+/- 0.073 mean_var=696.8612+/-141.430, 0's: 0 Z-trim(117.3): 51 B-trim: 0 in 0/55 Lambda= 0.048585 statistics sampled from 17949 (17995) to 17949 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.8), E-opt: 0.2 (0.553), width: 16 Scan time: 4.220 The best scores are: opt bits E(32554) CCDS9318.1 WASF3 gene_id:10810|Hs108|chr13 ( 502) 3451 256.5 4.8e-68 CCDS76626.1 WASF3 gene_id:10810|Hs108|chr13 ( 499) 3103 232.2 1.1e-60 CCDS304.1 WASF2 gene_id:10163|Hs108|chr1 ( 498) 1590 126.1 8.9e-29 CCDS5080.1 WASF1 gene_id:8936|Hs108|chr6 ( 559) 1182 97.6 3.9e-20 CCDS55582.1 WASF2 gene_id:10163|Hs108|chr1 ( 281) 944 80.6 2.6e-15 >>CCDS9318.1 WASF3 gene_id:10810|Hs108|chr13 (502 aa) initn: 3451 init1: 3451 opt: 3451 Z-score: 1335.0 bits: 256.5 E(32554): 4.8e-68 Smith-Waterman score: 3451; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502) 10 20 30 40 50 60 pF1KA0 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVYHGASSEGSLSPDTRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVYHGASSEGSLSPDTRS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 HASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 HASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 PQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 SPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 GPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 GPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR 430 440 450 460 470 480 490 500 pF1KA0 RIAVEYSDSDDDSEFDENDWSD :::::::::::::::::::::: CCDS93 RIAVEYSDSDDDSEFDENDWSD 490 500 >>CCDS76626.1 WASF3 gene_id:10810|Hs108|chr13 (499 aa) initn: 1882 init1: 1882 opt: 3103 Z-score: 1203.2 bits: 232.2 E(32554): 1.1e-60 Smith-Waterman score: 3103; 90.9% identity (95.4% similar) in 504 aa overlap (1-502:1-499) 10 20 30 40 50 60 pF1KA0 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 EQK-RIDGTTREVKKVRKARNRRQEWNMMAYDKELRPD-NRLSQSVYHGASSEGSLSPDT ..: ... . . .:::.:.:..::. . :. : ..: :. :...: . : . CCDS76 REKHKLNPNRNQQVNVRKVRTRKEEWERRKMGIEFMSDAKKLEQA---GSAKEDRV-P-S 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 RSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMAL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 GSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMAL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA0 NRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 NRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTA 300 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 FVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 FVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSP 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 MHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 MHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATIL 420 430 440 450 460 470 480 490 500 pF1KA0 SRRIAVEYSDSDDDSEFDENDWSD :::::::::::::::::::::::: CCDS76 SRRIAVEYSDSDDDSEFDENDWSD 480 490 >>CCDS304.1 WASF2 gene_id:10163|Hs108|chr1 (498 aa) initn: 869 init1: 869 opt: 1590 Z-score: 630.1 bits: 126.1 E(32554): 8.9e-29 Smith-Waterman score: 1590; 50.6% identity (70.7% similar) in 516 aa overlap (1-502:1-498) 10 20 30 40 50 60 pF1KA0 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN :::: :::::::::: .:: .. :::::::: ::: .::::.::::.:::::::::..:: CCDS30 MPLVTRNIEPRHLCRQTLP-SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP .: :..:: .:.::: ::::::: :::::: :: .:::.:::.:::.. ..::.: : CCDS30 TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK : . :: : ::::: ::::::: :..::::::::::::::::::::::.: ::::... CCDS30 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR 120 130 140 150 160 170 190 200 210 220 230 pF1KA0 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKEL-RPDNRLSQSVYHGA--SSEGSLSPD ..:. :. .: . :: ..:..::. : . .:. . ..:. : : . ..::.. CCDS30 KEKK-DNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIG-- 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 TRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPA--SQAAEHEYRPPSASARH . .: ::: :. . .: .::.. ..:: :: : .... :. .. CCDS30 ---CVENVDASSYPPPPQSDSASSP-SPSFSEDNLPPP-PAEFSYPVDNQRGSGLAGPKR 240 250 260 270 280 290 300 310 320 330 340 pF1KA0 MALNRPQQPPPPPPPQAPEGSQ-------ASAPMAPADYGMLPAQIIEYYNPSGPPPPPP .. :..::: :: .: : . : : : :. : .. : :::: CCDS30 SSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KA0 PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPP :: .: . :..: : :: ::. : :: :: ::::: ::::::::: CCDS30 PPSFPP-HPDFAAP---PPPPPPPAADYPTLPPPPLSQPTG---GAPPPP-PPPPPPGPP 360 370 380 390 400 410 420 430 440 450 460 pF1KA0 GPG-SSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKR : .. ...: ::.... . . . : .::::::::.:::.:.::..:.:::::: :: CCDS30 PPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE-KR 410 420 430 440 450 460 470 480 490 500 pF1KA0 EPVGNDVATILSRRIAVEYSDSDDDS-EFDENDWSD . ::::::::::::::::::::.::: ::::.:::: CCDS30 DVVGNDVATILSRRIAVEYSDSEDDSSEFDEDDWSD 470 480 490 >>CCDS5080.1 WASF1 gene_id:8936|Hs108|chr6 (559 aa) initn: 1494 init1: 915 opt: 1182 Z-score: 474.9 bits: 97.6 E(32554): 3.9e-20 Smith-Waterman score: 1424; 48.2% identity (63.3% similar) in 537 aa overlap (1-477:1-534) 10 20 30 40 50 60 pF1KA0 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN ::::::::.:::::. :::.:: .::::::: .:: ::::::::::.::::::::::::. CCDS50 MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP .: .:.::::.:.:::.:.::::: ::.:::::.:.:::.:::.::::. .....: : CCDS50 SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK . . :. ..::::::::::::: :.::::::.::::::::::::::::::::::::.:: CCDS50 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPD--NRLSQS--VYHGASSEGSLSP :: .: . : : ..::.::. .: :: : : : . : .: .:. : CCDS50 -QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRP 190 200 210 220 230 240 250 260 270 280 pF1KA0 DTRSHASDVTDYSYPATPNHSL---------------H-PQPVTPSYAAGDVPPHGPASQ .: : .:: : : .. : : : : ..:::. : . CCDS50 QTYVDHMD-GSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCIS 240 250 260 270 280 290 290 300 310 320 330 pF1KA0 AAEH--EYRPPS-ASARHMALNRPQQPPPPPP-PQAPEGSQASAPMA----PADYGMLPA .: : :: : :..: .. : :::::: :.: :. : :. : : CCDS50 SATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPP 300 310 320 330 340 350 340 350 360 370 380 pF1KA0 QIIEYYNPSGPPPPPP----PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPST :. :::: : : :. : .. :: .: .:: .: ...: :: CCDS50 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP-SPPVARAAPVCETVPVHPLPQ 360 370 380 390 400 410 390 400 410 420 pF1KA0 GLLVTAPPPPGPPP-PPPG--------------PPG---------PGSSLSSSPMHGP-- : . :::: ::: :::: ::. :: . : : CCDS50 GEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQ 420 430 440 450 460 470 430 440 450 460 470 480 pF1KA0 --PVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR :..: ::. . : :::::: :: ::: ::::.::.::::::::.: . :::::: CCDS50 VIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSR 480 490 500 510 520 530 490 500 pF1KA0 RIAVEYSDSDDDSEFDENDWSD CCDS50 RIAVEYSDSEDDSEFDEVDWLE 540 550 >>CCDS55582.1 WASF2 gene_id:10163|Hs108|chr1 (281 aa) initn: 921 init1: 746 opt: 944 Z-score: 388.5 bits: 80.6 E(32554): 2.6e-15 Smith-Waterman score: 944; 54.4% identity (76.2% similar) in 281 aa overlap (1-278:1-272) 10 20 30 40 50 60 pF1KA0 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN :::: :::::::::: .:: .. :::::::: ::: .::::.::::.:::::::::..:: CCDS55 MPLVTRNIEPRHLCRQTLP-SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP .: :..:: .:.::: ::::::: :::::: :: .:::.:::.:::.. ..::.: : CCDS55 TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK : . :: : ::::: ::::::: :..::::::::::::::::::::::.: ::::... CCDS55 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR 120 130 140 150 160 170 190 200 210 220 230 pF1KA0 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKEL-RPDNRLSQSVYHGA--SSEGSLSPD ..:. :. .: . :: ..:..::. : . .:. . ..:. : : . ..::.. CCDS55 KEKK-DNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIG-- 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 TRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMA . .: ::: :. . .: .::.. ..:: :: CCDS55 ---CVENVDASSYPPPPQSDSASSP-SPSFSEDNLPPP-PAEFRFSAAQG 240 250 260 270 280 300 310 320 330 340 350 pF1KA0 LNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQT 502 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:54:40 2016 done: Wed Nov 2 19:54:41 2016 Total Scan time: 4.220 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]