Result of FASTA (omim) for
pF1KA0901
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0901, 1215 aa
1>>>pF1KA0901 1215 - 1215 aa - 1215 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8455+/-0.000378; mu= 15.7840+/- 0.024
mean_var=122.7142+/-25.379, 0's: 0 Z-trim(116.1): 168 B-trim: 1160 in 1/58
Lambda= 0.115778
statistics sampled from 26900 (27081) to 26900 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.318), width: 16
Scan time: 16.800
The best scores are: opt bits E(85289)
NP_001308158 (OMIM: 300272,300863) histone deacety (1215) 8196 1381.2 0
NP_006035 (OMIM: 300272,300863) histone deacetylas (1215) 8196 1381.2 0
NP_001308156 (OMIM: 300272,300863) histone deacety (1215) 8196 1381.2 0
NP_001308157 (OMIM: 300272,300863) histone deacety (1215) 8196 1381.2 0
NP_001308155 (OMIM: 300272,300863) histone deacety (1215) 8196 1381.2 0
NP_001308154 (OMIM: 300272,300863) histone deacety (1229) 8196 1381.2 0
XP_016884676 (OMIM: 300272,300863) PREDICTED: hist ( 622) 4043 687.3 8e-197
NP_114408 (OMIM: 608544) histone deacetylase 10 is ( 669) 1378 242.2 8.4e-63
NP_001152758 (OMIM: 608544) histone deacetylase 10 ( 649) 997 178.6 1.2e-43
NP_001308159 (OMIM: 300272,300863) histone deacety ( 146) 952 170.6 6.6e-42
NP_001308160 (OMIM: 300272,300863) histone deacety ( 146) 952 170.6 6.6e-42
XP_011510532 (OMIM: 605314) PREDICTED: histone dea ( 673) 774 141.3 2e-32
XP_016860884 (OMIM: 605314) PREDICTED: histone dea ( 917) 774 141.4 2.5e-32
XP_011510529 (OMIM: 605314) PREDICTED: histone dea (1041) 774 141.5 2.8e-32
XP_006712942 (OMIM: 605314) PREDICTED: histone dea (1062) 774 141.5 2.9e-32
XP_006712943 (OMIM: 605314) PREDICTED: histone dea (1062) 774 141.5 2.9e-32
XP_011510528 (OMIM: 605314) PREDICTED: histone dea (1065) 774 141.5 2.9e-32
XP_016860883 (OMIM: 605314) PREDICTED: histone dea (1069) 774 141.5 2.9e-32
XP_011510527 (OMIM: 605314) PREDICTED: histone dea (1079) 774 141.5 2.9e-32
NP_006028 (OMIM: 605314) histone deacetylase 4 [Ho (1084) 774 141.5 2.9e-32
XP_011510526 (OMIM: 605314) PREDICTED: histone dea (1084) 774 141.5 2.9e-32
XP_011510524 (OMIM: 605314) PREDICTED: histone dea (1089) 774 141.5 2.9e-32
XP_011510523 (OMIM: 605314) PREDICTED: histone dea (1089) 774 141.5 2.9e-32
XP_011510525 (OMIM: 605314) PREDICTED: histone dea (1089) 774 141.5 2.9e-32
XP_006712941 (OMIM: 605314) PREDICTED: histone dea (1089) 774 141.5 2.9e-32
XP_011510522 (OMIM: 605314) PREDICTED: histone dea (1090) 774 141.5 2.9e-32
XP_011510521 (OMIM: 605314) PREDICTED: histone dea (1103) 774 141.5 2.9e-32
XP_011510520 (OMIM: 605314) PREDICTED: histone dea (1108) 774 141.5 3e-32
XP_006712940 (OMIM: 605314) PREDICTED: histone dea (1108) 774 141.5 3e-32
XP_011510519 (OMIM: 605314) PREDICTED: histone dea (1113) 774 141.5 3e-32
XP_011536784 (OMIM: 606542) PREDICTED: histone dea ( 952) 738 135.4 1.7e-30
XP_011536783 (OMIM: 606542) PREDICTED: histone dea ( 952) 738 135.4 1.7e-30
NP_001091886 (OMIM: 606542) histone deacetylase 7 ( 954) 738 135.4 1.7e-30
NP_001295019 (OMIM: 606542) histone deacetylase 7 ( 974) 738 135.4 1.7e-30
NP_056216 (OMIM: 606542) histone deacetylase 7 iso ( 991) 738 135.4 1.7e-30
XP_011536782 (OMIM: 606542) PREDICTED: histone dea ( 998) 738 135.4 1.8e-30
XP_011536781 (OMIM: 606542) PREDICTED: histone dea ( 998) 738 135.4 1.8e-30
XP_016874944 (OMIM: 606542) PREDICTED: histone dea (1018) 738 135.4 1.8e-30
XP_011536780 (OMIM: 606542) PREDICTED: histone dea (1035) 738 135.4 1.8e-30
XP_016879485 (OMIM: 605315) PREDICTED: histone dea (1081) 720 132.5 1.5e-29
XP_011522452 (OMIM: 605315) PREDICTED: histone dea (1113) 720 132.5 1.5e-29
XP_016879484 (OMIM: 605315) PREDICTED: histone dea (1113) 720 132.5 1.5e-29
XP_011522451 (OMIM: 605315) PREDICTED: histone dea (1114) 720 132.5 1.5e-29
XP_016879483 (OMIM: 605315) PREDICTED: histone dea (1120) 720 132.5 1.5e-29
XP_005256963 (OMIM: 605315) PREDICTED: histone dea (1122) 720 132.5 1.5e-29
XP_005256962 (OMIM: 605315) PREDICTED: histone dea (1122) 720 132.5 1.5e-29
NP_005465 (OMIM: 605315) histone deacetylase 5 iso (1122) 720 132.5 1.5e-29
NP_001015053 (OMIM: 605315) histone deacetylase 5 (1123) 720 132.5 1.5e-29
XP_016879482 (OMIM: 605315) PREDICTED: histone dea (1152) 720 132.5 1.6e-29
XP_016879481 (OMIM: 605315) PREDICTED: histone dea (1156) 720 132.5 1.6e-29
>>NP_001308158 (OMIM: 300272,300863) histone deacetylase (1215 aa)
initn: 8196 init1: 8196 opt: 8196 Z-score: 7399.5 bits: 1381.2 E(85289): 0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215)
10 20 30 40 50 60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
1150 1160 1170 1180 1190 1200
1210
pF1KA0 IAHQNKFGEDMPHPH
:::::::::::::::
NP_001 IAHQNKFGEDMPHPH
1210
>>NP_006035 (OMIM: 300272,300863) histone deacetylase 6 (1215 aa)
initn: 8196 init1: 8196 opt: 8196 Z-score: 7399.5 bits: 1381.2 E(85289): 0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215)
10 20 30 40 50 60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
1150 1160 1170 1180 1190 1200
1210
pF1KA0 IAHQNKFGEDMPHPH
:::::::::::::::
NP_006 IAHQNKFGEDMPHPH
1210
>>NP_001308156 (OMIM: 300272,300863) histone deacetylase (1215 aa)
initn: 8196 init1: 8196 opt: 8196 Z-score: 7399.5 bits: 1381.2 E(85289): 0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215)
10 20 30 40 50 60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
1150 1160 1170 1180 1190 1200
1210
pF1KA0 IAHQNKFGEDMPHPH
:::::::::::::::
NP_001 IAHQNKFGEDMPHPH
1210
>>NP_001308157 (OMIM: 300272,300863) histone deacetylase (1215 aa)
initn: 8196 init1: 8196 opt: 8196 Z-score: 7399.5 bits: 1381.2 E(85289): 0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215)
10 20 30 40 50 60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
1150 1160 1170 1180 1190 1200
1210
pF1KA0 IAHQNKFGEDMPHPH
:::::::::::::::
NP_001 IAHQNKFGEDMPHPH
1210
>>NP_001308155 (OMIM: 300272,300863) histone deacetylase (1215 aa)
initn: 8196 init1: 8196 opt: 8196 Z-score: 7399.5 bits: 1381.2 E(85289): 0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215)
10 20 30 40 50 60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
1150 1160 1170 1180 1190 1200
1210
pF1KA0 IAHQNKFGEDMPHPH
:::::::::::::::
NP_001 IAHQNKFGEDMPHPH
1210
>>NP_001308154 (OMIM: 300272,300863) histone deacetylase (1229 aa)
initn: 8196 init1: 8196 opt: 8196 Z-score: 7399.4 bits: 1381.2 E(85289): 0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:15-1229)
10 20 30 40
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPN
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGANRGRGQASSTMTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 LAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 EGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 LADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYC
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 MFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPH
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 LKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 ALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDP
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA0 CPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA0 PVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA0 TPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAA
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA0 CRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA0 DWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA0 GPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLL
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA0 MGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQV
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA0 HRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSAS
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA0 FGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGA
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA0 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQ
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA0 TTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA0 ESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA0 LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYC
1150 1160 1170 1180 1190 1200
1190 1200 1210
pF1KA0 QAYVHHQALLDVKNIAHQNKFGEDMPHPH
:::::::::::::::::::::::::::::
NP_001 QAYVHHQALLDVKNIAHQNKFGEDMPHPH
1210 1220
>>XP_016884676 (OMIM: 300272,300863) PREDICTED: histone (622 aa)
initn: 4043 init1: 4043 opt: 4043 Z-score: 3654.6 bits: 687.3 E(85289): 8e-197
Smith-Waterman score: 4043; 100.0% identity (100.0% similar) in 597 aa overlap (1-597:15-611)
10 20 30 40
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPN
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGANRGRGQASSTMTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 LAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 EGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 LADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYC
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 MFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPH
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 LKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 ALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDP
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA0 CPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA0 PVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA0 TPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAA
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA0 CRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIV
:::::::::::
XP_016 CRLVEAVLSGEDPDCGLGCPPR
610 620
>>NP_114408 (OMIM: 608544) histone deacetylase 10 isofor (669 aa)
initn: 1492 init1: 1328 opt: 1378 Z-score: 1248.4 bits: 242.2 E(85289): 8.4e-63
Smith-Waterman score: 1414; 39.4% identity (62.6% similar) in 728 aa overlap (85-806:2-633)
60 70 80 90 100 110
pF1KA0 KMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSF--PEGPERL
::.:: :... . :::: : ::::
NP_114 MGTALVYHEDMTATRLLWDDPECEIERPERL
10 20 30
120 130 140 150 160 170
pF1KA0 HAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYD
: ..: :.:: .::. ..:: : .::: :::: ::..:.. :: ... ::..:. .:
NP_114 TAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFD
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA0 SVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVA
..:.::... :: ::.:. :.:::::: . ..::.:..::::::.:.. .:.:.::.::
NP_114 AIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA0 VAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNW
.:: .:.::: ..:.:.:::::::::: :. :..:::::::: ::::.::::: :. :.
NP_114 IAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDA
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA0 STTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDP
...: ::: :.:.:.::::::: .:::.:::::.:::.:.::.:.::::.::::. :::
NP_114 DAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPELVLVSAGFDSAIGDP
220 230 240 250 260 270
360 370 380 390 400 410
pF1KA0 KGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLES
.:.: ::: ::.::.::. ::::.. :::::.:..:::.: ...:::::: : : .
NP_114 EGQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAPPLSG
280 290 300 310 320 330
420 430 440 450 460 470
pF1KA0 PGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPIL
: :::.:: :.. : : : :. : .. :. . . .: : : ::.::
NP_114 PMAPCQSALESIQSARAAQAPHWKSLQQQDVTA----VPMSPSSHSPEGRP--PPLLP--
340 350 360 370 380
480 490 500 510 520
pF1KA0 TWPVLQ---SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPR
:: . : . . :: . : : .: : .. :.: :
NP_114 GGPVCKAAASAPSSLLDQPCL--C----------PAPSVRTAVALTTPDIT---LVLPPD
390 400 410 420
530 540 550 560 570 580
pF1KA0 PAT-EAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACR
:: : .. .. : :.. .: : : :
NP_114 VIQQEASALREETEAWA---RPHESLAREE--------------------ALTALGKLLY
430 440 450 460
590 600 610 620 630 640
pF1KA0 LVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDW
:....:.:.: .: :.. :. : :: .. ::.:.. .: : :.: :
NP_114 LLDGMLDGQVNSGIAAT--PASAA---AA-------TLDVAVRRG--LSHGAQRLLCVA-
470 480 490 500 510
650 660 670 680 690 700
pF1KA0 DVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGP
. . . . .: : :..... : :.:. .. : :.. :
NP_114 -LGQLDRPPDLAHDGRS-LWLNIR----------GKEAAALSM-------FHVSTPL--P
520 530 540
710 720 730 740 750 760
pF1KA0 RMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMG
: . .:. ::::.:: :.:.::::. : : : : .:.. : :. .: :
NP_114 VM-TGGFLSCILGLVLPLAYGFQPDLVLVALG-------PGHGLQ-GPHA-ALLAAMLRG
550 560 570 580 590
770 780 790 800 810 820
pF1KA0 LASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHR
::.::.. .:: .: . . .: : :. :: :
NP_114 LAGGRVLALLE----ENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLE
600 610 620 630 640 650
830 840 850 860 870 880
pF1KA0 RYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFG
NP_114 PQWKMLQCHPHLVA
660
>>NP_001152758 (OMIM: 608544) histone deacetylase 10 iso (649 aa)
initn: 1096 init1: 957 opt: 997 Z-score: 904.7 bits: 178.6 E(85289): 1.2e-43
Smith-Waterman score: 1271; 37.6% identity (60.2% similar) in 728 aa overlap (85-806:2-613)
60 70 80 90 100 110
pF1KA0 KMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSF--PEGPERL
::.:: :... . :::: : ::::
NP_001 MGTALVYHEDMTATRLLWDDPECEIERPERL
10 20 30
120 130 140 150 160 170
pF1KA0 HAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYD
: ..: :.:: .::. ..:: : .::: :::: ::..:.. :: ... ::..:. .:
NP_001 TAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFD
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA0 SVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVA
..:.::... :: ::.:. :.:::::: . ..::.:..::::::.:.. .:.:.::.::
NP_001 AIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA0 VAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNW
.:: .:.::: ..:.:.:::::::::: :. :..:::::::: ::::.::::: :. :.
NP_001 IAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDA
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA0 STTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDP
...: ::: :.:.:.::::::: .:::.:::::.:::.:.:
NP_001 DAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFE-------------------
220 230 240 250
360 370 380 390 400 410
pF1KA0 KGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLES
:.: ::: ::.::.::. ::::.. :::::.:..:::.: ...:::::: : : .
NP_001 -GQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAPPLSG
260 270 280 290 300 310
420 430 440 450 460 470
pF1KA0 PGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPIL
: :::.:: :.. : : : :. : .. :. . . .: : : ::.::
NP_001 PMAPCQSALESIQSARAAQAPHWKSLQQQDVTA----VPMSPSSHSPEGRP--PPLLP--
320 330 340 350 360
480 490 500 510 520
pF1KA0 TWPVLQ---SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPR
:: . : . . :: . : : .: : .. :.: :
NP_001 GGPVCKAAASAPSSLLDQPCL--C----------PAPSVRTAVALTTPDIT---LVLPPD
370 380 390 400
530 540 550 560 570 580
pF1KA0 PAT-EAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACR
:: : .. .. : :.. .: : : :
NP_001 VIQQEASALREETEAWA---RPHESLAREE--------------------ALTALGKLLY
410 420 430 440
590 600 610 620 630 640
pF1KA0 LVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDW
:....:.:.: .: :.. :. : :: .. ::.:.. .: : :.: :
NP_001 LLDGMLDGQVNSGIAAT--PASAA---AA-------TLDVAVRRG--LSHGAQRLLCVA-
450 460 470 480 490
650 660 670 680 690 700
pF1KA0 DVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGP
. . . . .: : :..... : :.:. .. : :.. :
NP_001 -LGQLDRPPDLAHDGRS-LWLNIR----------GKEAAALSM-------FHVSTPL--P
500 510 520
710 720 730 740 750 760
pF1KA0 RMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMG
: . .:. ::::.:: :.:.::::. : : : : .:.. : :. .: :
NP_001 VM-TGGFLSCILGLVLPLAYGFQPDLVLVALG-------PGHGLQ-GPHA-ALLAAMLRG
530 540 550 560 570
770 780 790 800 810 820
pF1KA0 LASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHR
::.::.. .:: .: . . .: : :. :: :
NP_001 LAGGRVLALLE----ENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLE
580 590 600 610 620 630
830 840 850 860 870 880
pF1KA0 RYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFG
NP_001 PQWKMLQCHPHLVA
640
>>NP_001308159 (OMIM: 300272,300863) histone deacetylase (146 aa)
initn: 952 init1: 952 opt: 952 Z-score: 873.3 bits: 170.6 E(85289): 6.6e-42
Smith-Waterman score: 952; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145)
10 20 30 40 50 60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
:::::::::::::::::::::::::
NP_001 QEGLLDRCVSFQARFAEKEELMLVHR
130 140
1215 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:30:53 2016 done: Thu Nov 3 10:30:55 2016
Total Scan time: 16.800 Total Display time: 0.310
Function used was FASTA [36.3.4 Apr, 2011]