FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0905, 1220 aa 1>>>pF1KA0905 1220 - 1220 aa - 1220 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.8065+/-0.000589; mu= -25.7697+/- 0.036 mean_var=746.2207+/-158.003, 0's: 0 Z-trim(121.2): 39 B-trim: 1330 in 2/59 Lambda= 0.046951 statistics sampled from 37349 (37390) to 37349 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.438), width: 16 Scan time: 17.640 The best scores are: opt bits E(85289) NP_001305049 (OMIM: 610257) protein transport prot (1220) 8250 575.5 7.4e-163 NP_001070675 (OMIM: 610257) protein transport prot (1220) 8250 575.5 7.4e-163 NP_001070676 (OMIM: 610257) protein transport prot (1205) 6637 466.2 5.7e-130 NP_001305048 (OMIM: 610257) protein transport prot (1205) 6637 466.2 5.7e-130 NP_001177978 (OMIM: 610257) protein transport prot (1200) 6461 454.3 2.2e-126 NP_001070674 (OMIM: 610257) protein transport prot (1106) 5987 422.2 9.5e-117 NP_057295 (OMIM: 610257) protein transport protein (1181) 4604 328.5 1.6e-88 NP_001287674 (OMIM: 610257) protein transport prot (1166) 3434 249.3 1.1e-64 NP_001287673 (OMIM: 610257) protein transport prot (1067) 3415 247.9 2.6e-64 NP_056305 (OMIM: 610258) protein transport protein (1179) 3291 239.6 9.4e-62 >>NP_001305049 (OMIM: 610257) protein transport protein (1220 aa) initn: 8250 init1: 8250 opt: 8250 Z-score: 3044.8 bits: 575.5 E(85289): 7.4e-163 Smith-Waterman score: 8250; 100.0% identity (100.0% similar) in 1220 aa overlap (1-1220:1-1220) 10 20 30 40 50 60 pF1KA0 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1150 1160 1170 1180 1190 1200 1210 1220 pF1KA0 TSAFMPVLKVVLTQANKLGV :::::::::::::::::::: NP_001 TSAFMPVLKVVLTQANKLGV 1210 1220 >>NP_001070675 (OMIM: 610257) protein transport protein (1220 aa) initn: 8250 init1: 8250 opt: 8250 Z-score: 3044.8 bits: 575.5 E(85289): 7.4e-163 Smith-Waterman score: 8250; 100.0% identity (100.0% similar) in 1220 aa overlap (1-1220:1-1220) 10 20 30 40 50 60 pF1KA0 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1150 1160 1170 1180 1190 1200 1210 1220 pF1KA0 TSAFMPVLKVVLTQANKLGV :::::::::::::::::::: NP_001 TSAFMPVLKVVLTQANKLGV 1210 1220 >>NP_001070676 (OMIM: 610257) protein transport protein (1205 aa) initn: 6607 init1: 6607 opt: 6637 Z-score: 2454.4 bits: 466.2 E(85289): 5.7e-130 Smith-Waterman score: 8117; 98.8% identity (98.8% similar) in 1220 aa overlap (1-1220:1-1205) 10 20 30 40 50 60 pF1KA0 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI ::::::::::::::: :::::::::::::::::::::::::::::: NP_001 PPSSSAYALPPGTTG---------------PQNGWNDPPALNRVPKKKKMPENFMPPVPI 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KA0 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KA0 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KA0 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1130 1140 1150 1160 1170 1180 1210 1220 pF1KA0 TSAFMPVLKVVLTQANKLGV :::::::::::::::::::: NP_001 TSAFMPVLKVVLTQANKLGV 1190 1200 >>NP_001305048 (OMIM: 610257) protein transport protein (1205 aa) initn: 6607 init1: 6607 opt: 6637 Z-score: 2454.4 bits: 466.2 E(85289): 5.7e-130 Smith-Waterman score: 8117; 98.8% identity (98.8% similar) in 1220 aa overlap (1-1220:1-1205) 10 20 30 40 50 60 pF1KA0 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI ::::::::::::::: :::::::::::::::::::::::::::::: NP_001 PPSSSAYALPPGTTG---------------PQNGWNDPPALNRVPKKKKMPENFMPPVPI 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KA0 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KA0 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KA0 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1130 1140 1150 1160 1170 1180 1210 1220 pF1KA0 TSAFMPVLKVVLTQANKLGV :::::::::::::::::::: NP_001 TSAFMPVLKVVLTQANKLGV 1190 1200 >>NP_001177978 (OMIM: 610257) protein transport protein (1200 aa) initn: 6431 init1: 6431 opt: 6461 Z-score: 2390.0 bits: 454.3 E(85289): 2.2e-126 Smith-Waterman score: 7941; 98.7% identity (98.7% similar) in 1194 aa overlap (27-1220:22-1200) 10 20 30 40 50 60 pF1KA0 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC :::::::::::::::::::::::::::::::::: NP_001 MLGESDERCTNAGSGCRRSSPGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA0 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA0 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA0 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA0 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA0 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA0 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA0 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI ::::::::::::::: :::::::::::::::::::::::::::::: NP_001 PPSSSAYALPPGTTG---------------PQNGWNDPPALNRVPKKKKMPENFMPPVPI 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KA0 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KA0 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KA0 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1130 1140 1150 1160 1170 1180 1210 1220 pF1KA0 TSAFMPVLKVVLTQANKLGV :::::::::::::::::::: NP_001 TSAFMPVLKVVLTQANKLGV 1190 1200 >>NP_001070674 (OMIM: 610257) protein transport protein (1106 aa) initn: 5936 init1: 5896 opt: 5987 Z-score: 2217.0 bits: 422.2 E(85289): 9.5e-117 Smith-Waterman score: 7212; 90.7% identity (90.7% similar) in 1220 aa overlap (1-1220:1-1106) 10 20 30 40 50 60 pF1KA0 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA ::::::::::::::::::::::::::::::::::: ::: NP_001 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQ------------------RPQ---- 850 860 870 910 920 930 940 950 960 pF1KA0 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA NP_001 ------------------------------------------------------------ 970 980 990 1000 1010 1020 pF1KA0 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI :::::::::::::::::::::::::::: NP_001 --------------------------------NGWNDPPALNRVPKKKKMPENFMPPVPI 880 890 900 1030 1040 1050 1060 1070 1080 pF1KA0 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 910 920 930 940 950 960 1090 1100 1110 1120 1130 1140 pF1KA0 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 970 980 990 1000 1010 1020 1150 1160 1170 1180 1190 1200 pF1KA0 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1030 1040 1050 1060 1070 1080 1210 1220 pF1KA0 TSAFMPVLKVVLTQANKLGV :::::::::::::::::::: NP_001 TSAFMPVLKVVLTQANKLGV 1090 1100 >>NP_057295 (OMIM: 610257) protein transport protein Sec (1181 aa) initn: 4598 init1: 4598 opt: 4604 Z-score: 1710.3 bits: 328.5 E(85289): 1.6e-88 Smith-Waterman score: 7924; 96.8% identity (96.8% similar) in 1220 aa overlap (1-1220:1-1181) 10 20 30 40 50 60 pF1KA0 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL ::::::::::::::::::::::: NP_057 FEDDSRGKYLELLGYRKEDLGKK------------------------------------- 490 500 550 560 570 580 590 600 pF1KA0 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 --HIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 510 520 530 540 550 560 610 620 630 640 650 660 pF1KA0 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 570 580 590 600 610 620 670 680 690 700 710 720 pF1KA0 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 630 640 650 660 670 680 730 740 750 760 770 780 pF1KA0 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 690 700 710 720 730 740 790 800 810 820 830 840 pF1KA0 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 750 760 770 780 790 800 850 860 870 880 890 900 pF1KA0 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 810 820 830 840 850 860 910 920 930 940 950 960 pF1KA0 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 870 880 890 900 910 920 970 980 990 1000 1010 1020 pF1KA0 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI 930 940 950 960 970 980 1030 1040 1050 1060 1070 1080 pF1KA0 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 990 1000 1010 1020 1030 1040 1090 1100 1110 1120 1130 1140 pF1KA0 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1050 1060 1070 1080 1090 1100 1150 1160 1170 1180 1190 1200 pF1KA0 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1110 1120 1130 1140 1150 1160 1210 1220 pF1KA0 TSAFMPVLKVVLTQANKLGV :::::::::::::::::::: NP_057 TSAFMPVLKVVLTQANKLGV 1170 1180 >>NP_001287674 (OMIM: 610257) protein transport protein (1166 aa) initn: 4987 init1: 3415 opt: 3434 Z-score: 1282.1 bits: 249.3 E(85289): 1.1e-64 Smith-Waterman score: 7791; 95.6% identity (95.6% similar) in 1220 aa overlap (1-1220:1-1166) 10 20 30 40 50 60 pF1KA0 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL ::::::::::::::::::::::: NP_001 FEDDSRGKYLELLGYRKEDLGKK------------------------------------- 490 500 550 560 570 580 590 600 pF1KA0 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 --HIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 510 520 530 540 550 560 610 620 630 640 650 660 pF1KA0 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 570 580 590 600 610 620 670 680 690 700 710 720 pF1KA0 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 630 640 650 660 670 680 730 740 750 760 770 780 pF1KA0 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 690 700 710 720 730 740 790 800 810 820 830 840 pF1KA0 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 750 760 770 780 790 800 850 860 870 880 890 900 pF1KA0 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 810 820 830 840 850 860 910 920 930 940 950 960 pF1KA0 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 870 880 890 900 910 920 970 980 990 1000 1010 1020 pF1KA0 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI ::::::::::::::: :::::::::::::::::::::::::::::: NP_001 PPSSSAYALPPGTTG---------------PQNGWNDPPALNRVPKKKKMPENFMPPVPI 930 940 950 960 1030 1040 1050 1060 1070 1080 pF1KA0 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 970 980 990 1000 1010 1020 1090 1100 1110 1120 1130 1140 pF1KA0 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1030 1040 1050 1060 1070 1080 1150 1160 1170 1180 1190 1200 pF1KA0 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1090 1100 1110 1120 1130 1140 1210 1220 pF1KA0 TSAFMPVLKVVLTQANKLGV :::::::::::::::::::: NP_001 TSAFMPVLKVVLTQANKLGV 1150 1160 >>NP_001287673 (OMIM: 610257) protein transport protein (1067 aa) initn: 4961 init1: 3415 opt: 3415 Z-score: 1275.7 bits: 247.9 E(85289): 2.6e-64 Smith-Waterman score: 6886; 87.5% identity (87.5% similar) in 1220 aa overlap (1-1220:1-1067) 10 20 30 40 50 60 pF1KA0 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL ::::::::::::::::::::::: NP_001 FEDDSRGKYLELLGYRKEDLGKK------------------------------------- 490 500 550 560 570 580 590 600 pF1KA0 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 --HIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 510 520 530 540 550 560 610 620 630 640 650 660 pF1KA0 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 570 580 590 600 610 620 670 680 690 700 710 720 pF1KA0 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 630 640 650 660 670 680 730 740 750 760 770 780 pF1KA0 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 690 700 710 720 730 740 790 800 810 820 830 840 pF1KA0 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 750 760 770 780 790 800 850 860 870 880 890 900 pF1KA0 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA ::::::::::::::::::::::::::::::::::: ::: NP_001 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQ------------------RPQ---- 810 820 830 910 920 930 940 950 960 pF1KA0 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA NP_001 ------------------------------------------------------------ 970 980 990 1000 1010 1020 pF1KA0 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI :::::::::::::::::::::::::::: NP_001 --------------------------------NGWNDPPALNRVPKKKKMPENFMPPVPI 840 850 860 1030 1040 1050 1060 1070 1080 pF1KA0 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 870 880 890 900 910 920 1090 1100 1110 1120 1130 1140 pF1KA0 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 930 940 950 960 970 980 1150 1160 1170 1180 1190 1200 pF1KA0 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 990 1000 1010 1020 1030 1040 1210 1220 pF1KA0 TSAFMPVLKVVLTQANKLGV :::::::::::::::::::: NP_001 TSAFMPVLKVVLTQANKLGV 1050 1060 >>NP_056305 (OMIM: 610258) protein transport protein Sec (1179 aa) initn: 2122 init1: 1288 opt: 3291 Z-score: 1229.7 bits: 239.6 E(85289): 9.4e-62 Smith-Waterman score: 3648; 47.5% identity (72.1% similar) in 1247 aa overlap (1-1220:1-1179) 10 20 30 40 50 60 pF1KA0 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC :::::..: :.::::::...:.::::::::::::..::::..:::::.:. :::::.: NP_056 MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK ...:. :.:::.:: . .. . :::...::.:: .:::. ..:... :: ::::..: NP_056 GVLSALSRFHKLVWGSFG-SGLLESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQK 70 80 90 100 110 130 140 150 160 170 pF1KA0 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQ-PPEDISCIAWNRQ ::: :::::.: :: ::.::::..:::.::::::. .::: :.:.: :::::. ..:::: NP_056 HTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQ 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 VQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLP .::::.:: :::.:.::::::::::::::::::::::::::::::.:::.:: ::::::: NP_056 AQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 VIQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYEL :::.::::::::::.:::.:.::::...::.:: ::::. .::..::: : ...::.:.: NP_056 VIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA0 PTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPF ::...::::.:::::.:.:.:::::.: ::.::.:: : . ...:.::.::::.. NP_056 PTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSK---- 300 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 GTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAE ::::::::.:.:.:: .. ::::::::::::.:.::.:::::::: :.: NP_056 --GQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAHL--V 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 QQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKV : . ::::::.::.::: :: .::.:. : ...::::.: . . . :: .:.:::: NP_056 PQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKV 420 430 440 450 460 470 480 490 500 510 520 530 pF1KA0 NFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSD-GEESPAAEEQ ..:.::: :.:.:::: :..: ::.: :. ..:.: .: : .: . . : . NP_056 TLEQDSRMKFLKLLGYSKDELQKKVATWLK----SDVGLGESPQPKGNDLNSDRQQAFCS 480 490 500 510 520 540 550 560 570 580 590 pF1KA0 LLGEHIKEEKEES-----EFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDN ..: .: : :..:.. ..: .. :::::..:::: :.. ::.:::... NP_056 QASKHTTKEASASSAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEE 530 540 550 560 570 580 600 610 620 630 640 650 pF1KA0 RMADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREAL :.::::::: ::: .:: .::..:.::...::. :.. ::.::::..: .:.:::::::: NP_056 RFADAIILAQAGGTDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREAL 590 600 610 620 630 640 660 670 680 690 700 710 pF1KA0 AAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSH : .:::. ..: :::.::::.:.::. : ..: :::.:.:.::.:: ::.: ... NP_056 ALLLTYSGTEKFPELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALS 650 660 670 680 690 700 720 730 740 750 760 770 pF1KA0 PLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDN :..::::.:::..: .... .. . : . ...:::::::::::.:.:..::: . NP_056 PMALQDLMEKVMVLNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRD 710 720 730 740 750 760 780 790 800 810 820 pF1KA0 TNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEK---------QQLPKGRPGPVAGHH--- :: ..:::::: .::: : :..:: .:. . .. . : : .:. NP_056 CAQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPT 770 780 790 800 810 820 830 840 850 860 870 pF1KA0 --QMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQP ::: : : : : ..: . : . .:: . : : : .: NP_056 PSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDY--RAPGPQAIQ--PLPLSPGVRP 830 840 850 860 870 880 880 890 900 910 920 930 pF1KA0 AQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYT--GQSQLYAAQHQASSPTS :. : ::. . :. ::. : . :..: . . :...: .: NP_056 ASSQPQLLGGQRVQVPN-PVGFPGTWPLPGSPLPMACPGIMRPGSTSL------PETPRL 890 900 910 920 930 940 950 960 970 980 990 pF1KA0 SPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPAS----QRTGPQN : . : . : .: : :::.: :: :. : .: ::.. . :::. NP_056 FPLLPLRPL-GPGRMVSHT-P-APPASFPVPYLPGDPGA-PCSSVLPTTGILTPHPGPQD 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 pF1KA0 GWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFP .:.. :: ...:.::.::::.:::.:.:. :. : . :: : :.:: : NP_056 SWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLT--PELQGIL--PSQP-PVSSVS--- 1000 1010 1020 1030 1040 1060 1070 1080 1090 1100 1110 pF1KA0 QPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIP : : ::.: :. ..: :: .:. .: .: NP_056 --HAP-----------------------------PGVP-GELSLQLQHLPPEKMERKELP 1050 1060 1070 1120 1130 1140 1150 1160 1170 pF1KA0 DEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTLSPTITSGLHNI :: ::..:: :.::: :::: .:::::..:..:::.::.:: : :::: ...:::.. NP_056 PEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGTLSPHVVAGLHEV 1080 1090 1100 1110 1120 1130 1180 1190 1200 1210 1220 pF1KA0 ARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKLGV :: ... .. .::..:..... :.:::.:.:::.::.:: :.:: : NP_056 ARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKLLV 1140 1150 1160 1170 1220 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:31:40 2016 done: Thu Nov 3 10:31:43 2016 Total Scan time: 17.640 Total Display time: 0.550 Function used was FASTA [36.3.4 Apr, 2011]