FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0906, 1887 aa 1>>>pF1KA0906 1887 - 1887 aa - 1887 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4201+/-0.000445; mu= 19.7649+/- 0.028 mean_var=95.3440+/-18.913, 0's: 0 Z-trim(111.3): 15 B-trim: 0 in 0/56 Lambda= 0.131349 statistics sampled from 19807 (19814) to 19807 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.567), E-opt: 0.2 (0.232), width: 16 Scan time: 18.280 The best scores are: opt bits E(85289) NP_079199 (OMIM: 607703) nuclear pore membrane gly (1887) 12180 2319.9 0 XP_016861510 (OMIM: 607703) PREDICTED: nuclear por ( 951) 6109 1169.3 0 XP_011531840 (OMIM: 607703) PREDICTED: nuclear por (1012) 6109 1169.3 0 XP_005265051 (OMIM: 607703) PREDICTED: nuclear por (1034) 6109 1169.3 0 XP_016861509 (OMIM: 607703) PREDICTED: nuclear por ( 992) 6072 1162.3 0 XP_016861507 (OMIM: 607703) PREDICTED: nuclear por (1015) 6072 1162.3 0 XP_016861508 (OMIM: 607703) PREDICTED: nuclear por (1004) 6071 1162.1 0 >>NP_079199 (OMIM: 607703) nuclear pore membrane glycopr (1887 aa) initn: 12180 init1: 12180 opt: 12180 Z-score: 12465.4 bits: 2319.9 E(85289): 0 Smith-Waterman score: 12180; 99.7% identity (99.8% similar) in 1887 aa overlap (1-1887:1-1887) 10 20 30 40 50 60 pF1KA0 MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWLSTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 PEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 PEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 IVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRIL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 TFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 TFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPTRPV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: NP_079 ENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPARPV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 AVLAQDTSMVTALQLGQSSLVLGHRSIRMQGASRLPNSTIYVVEPGYLGFTVHPGDRWVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 AVLAQDTSMVTALQLGQSSLVLGHRSIRMQGASRLPNSTIYVVEPGYLGFTVHPGDRWVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 ETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 ETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYTIRAHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 IDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYTIRAHG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 GSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 APCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 APCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GSEHCSGVRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSSVALVTLGSSK :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 GSEHCSGIRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSSVALVTLGSSK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 EMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 EMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 ALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SHRNPLLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEAELPMQLVSQDDESGQKKLH ::::: :::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_079 SHRNPRLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEPELPMQLVSQDDESGQKKLH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 GLQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVPLSASIELILVEDVRVSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 GLQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVPLSASIELILVEDVRVSPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 EVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 LCLVFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 LCLVFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 LRAASPIITLVALDEALDNYTITFLIRGVAIGQTSLTASVTNKAGQRINSAPQQIEVFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 LRAASPIITLVALDEALDNYTITFLIRGVAIGQTSLTASVTNKAGQRINSAPQQIEVFPP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 FRLMPRKVTLLIGATMQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 FRLMPRKVTLLIGATMQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LVQAVDAETGKVVIISQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 LVQAVDAETGKVVIISQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 FGNAVPGLTFHWSVTKRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 FGNAVPGLTFHWSVTKRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 DPTSGQLYGLARELSDEIQVQVFEKLQLLNPEIEAEQILMSPNSYIKLQTNRDGAASLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 DPTSGQLYGLARELSDEIQVQVFEKLQLLNPEIEAEQILMSPNSYIKLQTNRDGAASLSY 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 RVLDGPEKVPVVHVDEKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 RVLDGPEKVPVVHVDEKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 MSPVLHTQNKEALVAVPLGMTVTFTVHFHDNSGDVFHAHSSVLNFATNRDDFVQIGKGPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MSPVLHTQNKEALVAVPLGMTVTFTVHFHDNSGDVFHAHSSVLNFATNRDDFVQIGKGPT 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 NNTCVVRTVSVGLTLLRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 NNTCVVRTVSVGLTLLRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTS 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 LEGLSGTWSSSANSILHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQRIMAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 LEGLSGTWSSSANSILHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQRIMAR 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 HLHPIQTSFQEATASKVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 HLHPIQTSFQEATASKVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVF 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 DFPSQDVFTVEPQFDTALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 DFPSQDVFTVEPQFDTALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQ 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 VGAEVPFSPGLFADQAEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 VGAEVPFSPGLFADQAEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFG 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 WPSFITYTVGVSDPAAGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRGPGPYGASLF ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: NP_079 WPSFITYTVGVLDPAAGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRGPGPYGASLF 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 QHFLDSYQVMFFTLFALLAGTAVMIIAYHTVCTPRDLAVPAALTPRASPGHSPHYFAASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 QHFLDSYQVMFFTLFALLAGTAVMIIAYHTVCTPRDLAVPAALTPRASPGHSPHYFAASS 1810 1820 1830 1840 1850 1860 1870 1880 pF1KA0 PTSPNALPPARKASPPSGLWSPAYASH ::::::::::::::::::::::::::: NP_079 PTSPNALPPARKASPPSGLWSPAYASH 1870 1880 >>XP_016861510 (OMIM: 607703) PREDICTED: nuclear pore me (951 aa) initn: 6109 init1: 6109 opt: 6109 Z-score: 6252.4 bits: 1169.3 E(85289): 0 Smith-Waterman score: 6109; 99.6% identity (99.8% similar) in 945 aa overlap (1-945:1-945) 10 20 30 40 50 60 pF1KA0 MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWLSTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 PEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRIL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 TFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPTRPV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_016 ENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPARPV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 AVLAQDTSMVTALQLGQSSLVLGHRSIRMQGASRLPNSTIYVVEPGYLGFTVHPGDRWVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVLAQDTSMVTALQLGQSSLVLGHRSIRMQGASRLPNSTIYVVEPGYLGFTVHPGDRWVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 ETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYTIRAHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYTIRAHG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 APCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GSEHCSGVRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSSVALVTLGSSK :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSEHCSGIRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSSVALVTLGSSK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 EMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SHRNPLLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEAELPMQLVSQDDESGQKKLH ::::: :::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_016 SHRNPRLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEPELPMQLVSQDDESGQKKLH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 GLQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVPLSASIELILVEDVRVSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVPLSASIELILVEDVRVSPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHD ::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMSSRRNP 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA0 LCLVFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLK >>XP_011531840 (OMIM: 607703) PREDICTED: nuclear pore me (1012 aa) initn: 6109 init1: 6109 opt: 6109 Z-score: 6252.0 bits: 1169.3 E(85289): 0 Smith-Waterman score: 6109; 99.6% identity (99.8% similar) in 945 aa overlap (1-945:1-945) 10 20 30 40 50 60 pF1KA0 MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWLSTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 PEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRIL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 TFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPTRPV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_011 ENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPARPV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 AVLAQDTSMVTALQLGQSSLVLGHRSIRMQGASRLPNSTIYVVEPGYLGFTVHPGDRWVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVLAQDTSMVTALQLGQSSLVLGHRSIRMQGASRLPNSTIYVVEPGYLGFTVHPGDRWVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 ETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYTIRAHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYTIRAHG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 APCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GSEHCSGVRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSSVALVTLGSSK :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSEHCSGIRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSSVALVTLGSSK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 EMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SHRNPLLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEAELPMQLVSQDDESGQKKLH ::::: :::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 SHRNPRLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEPELPMQLVSQDDESGQKKLH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 GLQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVPLSASIELILVEDVRVSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVPLSASIELILVEDVRVSPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHD ::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMACAKDSRNSNQALVP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 LCLVFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLK XP_011 LVSSEACRRNFPGSIDVSSKSWLLQKQLQATVSEGCLLVAVAFSSCRAAAQR 970 980 990 1000 1010 >>XP_005265051 (OMIM: 607703) PREDICTED: nuclear pore me (1034 aa) initn: 6109 init1: 6109 opt: 6109 Z-score: 6251.9 bits: 1169.3 E(85289): 0 Smith-Waterman score: 6109; 99.6% identity (99.8% similar) in 945 aa overlap (1-945:1-945) 10 20 30 40 50 60 pF1KA0 MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWLSTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 PEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRIL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 TFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPTRPV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_005 ENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPARPV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 AVLAQDTSMVTALQLGQSSLVLGHRSIRMQGASRLPNSTIYVVEPGYLGFTVHPGDRWVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVLAQDTSMVTALQLGQSSLVLGHRSIRMQGASRLPNSTIYVVEPGYLGFTVHPGDRWVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 ETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYTIRAHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYTIRAHG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 APCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GSEHCSGVRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSSVALVTLGSSK :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSEHCSGIRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSSVALVTLGSSK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 EMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SHRNPLLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEAELPMQLVSQDDESGQKKLH ::::: :::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_005 SHRNPRLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEPELPMQLVSQDDESGQKKLH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 GLQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVPLSASIELILVEDVRVSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVPLSASIELILVEDVRVSPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHD ::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMRLMLVSSCLAKRMFS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 LCLVFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLK XP_005 QRRASRRGRESHCSCSSQRQTLGWQDALSSWGHACGWRTLEEARSLRPQAASPKHSYPLI 970 980 990 1000 1010 1020 >>XP_016861509 (OMIM: 607703) PREDICTED: nuclear pore me (992 aa) initn: 6071 init1: 6071 opt: 6072 Z-score: 6214.3 bits: 1162.3 E(85289): 0 Smith-Waterman score: 6072; 99.0% identity (99.1% similar) in 954 aa overlap (934-1887:39-992) 910 920 930 940 950 960 pF1KA0 IYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHDLCL .: : : :::::::::::::::::: XP_016 EEVLEELTWMQEDCSEEGRWTWAWRMTWSQQVEAGERVQVFKVHPLLPGSSTIMIHDLCL 10 20 30 40 50 60 970 980 990 1000 1010 1020 pF1KA0 VFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLKLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLKLRA 70 80 90 100 110 120 1030 1040 1050 1060 1070 1080 pF1KA0 ASPIITLVALDEALDNYTITFLIRGVAIGQTSLTASVTNKAGQRINSAPQQIEVFPPFRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASPIITLVALDEALDNYTITFLIRGVAIGQTSLTASVTNKAGQRINSAPQQIEVFPPFRL 130 140 150 160 170 180 1090 1100 1110 1120 1130 1140 pF1KA0 MPRKVTLLIGATMQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSGLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPRKVTLLIGATMQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSGLVQ 190 200 210 220 230 240 1150 1160 1170 1180 1190 1200 pF1KA0 AVDAETGKVVIISQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFSFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVDAETGKVVIISQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFSFGN 250 260 270 280 290 300 1210 1220 1230 1240 1250 1260 pF1KA0 AVPGLTFHWSVTKRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAVDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVPGLTFHWSVTKRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAVDPT 310 320 330 340 350 360 1270 1280 1290 1300 1310 1320 pF1KA0 SGQLYGLARELSDEIQVQVFEKLQLLNPEIEAEQILMSPNSYIKLQTNRDGAASLSYRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGQLYGLARELSDEIQVQVFEKLQLLNPEIEAEQILMSPNSYIKLQTNRDGAASLSYRVL 370 380 390 400 410 420 1330 1340 1350 1360 1370 1380 pF1KA0 DGPEKVPVVHVDEKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVSMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGPEKVPVVHVDEKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVSMSP 430 440 450 460 470 480 1390 1400 1410 1420 1430 1440 pF1KA0 VLHTQNKEALVAVPLGMTVTFTVHFHDNSGDVFHAHSSVLNFATNRDDFVQIGKGPTNNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLHTQNKEALVAVPLGMTVTFTVHFHDNSGDVFHAHSSVLNFATNRDDFVQIGKGPTNNT 490 500 510 520 530 540 1450 1460 1470 1480 1490 1500 pF1KA0 CVVRTVSVGLTLLRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTSLEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CVVRTVSVGLTLLRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTSLEG 550 560 570 580 590 600 1510 1520 1530 1540 1550 1560 pF1KA0 LSGTWSSSANSILHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQRIMARHLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSGTWSSSANSILHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQRIMARHLH 610 620 630 640 650 660 1570 1580 1590 1600 1610 1620 pF1KA0 PIQTSFQEATASKVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVFDFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIQTSFQEATASKVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVFDFP 670 680 690 700 710 720 1630 1640 1650 1660 1670 1680 pF1KA0 SQDVFTVEPQFDTALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQVGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQDVFTVEPQFDTALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQVGA 730 740 750 760 770 780 1690 1700 1710 1720 1730 1740 pF1KA0 EVPFSPGLFADQAEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFGWPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVPFSPGLFADQAEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFGWPS 790 800 810 820 830 840 1750 1760 1770 1780 1790 1800 pF1KA0 FITYTVGVSDPAAGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRGPGPYGASLFQHF :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FITYTVGVLDPAAGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRGPGPYGASLFQHF 850 860 870 880 890 900 1810 1820 1830 1840 1850 1860 pF1KA0 LDSYQVMFFTLFALLAGTAVMIIAYHTVCTPRDLAVPAALTPRASPGHSPHYFAASSPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDSYQVMFFTLFALLAGTAVMIIAYHTVCTPRDLAVPAALTPRASPGHSPHYFAASSPTS 910 920 930 940 950 960 1870 1880 pF1KA0 PNALPPARKASPPSGLWSPAYASH :::::::::::::::::::::::: XP_016 PNALPPARKASPPSGLWSPAYASH 970 980 990 >>XP_016861507 (OMIM: 607703) PREDICTED: nuclear pore me (1015 aa) initn: 6071 init1: 6071 opt: 6072 Z-score: 6214.1 bits: 1162.3 E(85289): 0 Smith-Waterman score: 6072; 99.0% identity (99.1% similar) in 954 aa overlap (934-1887:62-1015) 910 920 930 940 950 960 pF1KA0 IYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHDLCL .: : : :::::::::::::::::: XP_016 EEVLEELTWMQEDCSEEGRWTWAWRMTWSQQVEAGERVQVFKVHPLLPGSSTIMIHDLCL 40 50 60 70 80 90 970 980 990 1000 1010 1020 pF1KA0 VFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLKLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLKLRA 100 110 120 130 140 150 1030 1040 1050 1060 1070 1080 pF1KA0 ASPIITLVALDEALDNYTITFLIRGVAIGQTSLTASVTNKAGQRINSAPQQIEVFPPFRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASPIITLVALDEALDNYTITFLIRGVAIGQTSLTASVTNKAGQRINSAPQQIEVFPPFRL 160 170 180 190 200 210 1090 1100 1110 1120 1130 1140 pF1KA0 MPRKVTLLIGATMQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSGLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPRKVTLLIGATMQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSGLVQ 220 230 240 250 260 270 1150 1160 1170 1180 1190 1200 pF1KA0 AVDAETGKVVIISQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFSFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVDAETGKVVIISQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFSFGN 280 290 300 310 320 330 1210 1220 1230 1240 1250 1260 pF1KA0 AVPGLTFHWSVTKRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAVDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVPGLTFHWSVTKRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAVDPT 340 350 360 370 380 390 1270 1280 1290 1300 1310 1320 pF1KA0 SGQLYGLARELSDEIQVQVFEKLQLLNPEIEAEQILMSPNSYIKLQTNRDGAASLSYRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGQLYGLARELSDEIQVQVFEKLQLLNPEIEAEQILMSPNSYIKLQTNRDGAASLSYRVL 400 410 420 430 440 450 1330 1340 1350 1360 1370 1380 pF1KA0 DGPEKVPVVHVDEKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVSMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGPEKVPVVHVDEKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVSMSP 460 470 480 490 500 510 1390 1400 1410 1420 1430 1440 pF1KA0 VLHTQNKEALVAVPLGMTVTFTVHFHDNSGDVFHAHSSVLNFATNRDDFVQIGKGPTNNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLHTQNKEALVAVPLGMTVTFTVHFHDNSGDVFHAHSSVLNFATNRDDFVQIGKGPTNNT 520 530 540 550 560 570 1450 1460 1470 1480 1490 1500 pF1KA0 CVVRTVSVGLTLLRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTSLEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CVVRTVSVGLTLLRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTSLEG 580 590 600 610 620 630 1510 1520 1530 1540 1550 1560 pF1KA0 LSGTWSSSANSILHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQRIMARHLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSGTWSSSANSILHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQRIMARHLH 640 650 660 670 680 690 1570 1580 1590 1600 1610 1620 pF1KA0 PIQTSFQEATASKVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVFDFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIQTSFQEATASKVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVFDFP 700 710 720 730 740 750 1630 1640 1650 1660 1670 1680 pF1KA0 SQDVFTVEPQFDTALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQVGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQDVFTVEPQFDTALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQVGA 760 770 780 790 800 810 1690 1700 1710 1720 1730 1740 pF1KA0 EVPFSPGLFADQAEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFGWPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVPFSPGLFADQAEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFGWPS 820 830 840 850 860 870 1750 1760 1770 1780 1790 1800 pF1KA0 FITYTVGVSDPAAGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRGPGPYGASLFQHF :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FITYTVGVLDPAAGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRGPGPYGASLFQHF 880 890 900 910 920 930 1810 1820 1830 1840 1850 1860 pF1KA0 LDSYQVMFFTLFALLAGTAVMIIAYHTVCTPRDLAVPAALTPRASPGHSPHYFAASSPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDSYQVMFFTLFALLAGTAVMIIAYHTVCTPRDLAVPAALTPRASPGHSPHYFAASSPTS 940 950 960 970 980 990 1870 1880 pF1KA0 PNALPPARKASPPSGLWSPAYASH :::::::::::::::::::::::: XP_016 PNALPPARKASPPSGLWSPAYASH 1000 1010 >>XP_016861508 (OMIM: 607703) PREDICTED: nuclear pore me (1004 aa) initn: 6071 init1: 6071 opt: 6071 Z-score: 6213.2 bits: 1162.1 E(85289): 0 Smith-Waterman score: 6071; 99.9% identity (99.9% similar) in 942 aa overlap (946-1887:63-1004) 920 930 940 950 960 970 pF1KA0 IREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHDLCLVFPAPAKAVVYV :::::::::::::::::::::::::::::: XP_016 EVLEELTWMQEDCSEEGRWTWAWRMTWSQQVHPLLPGSSTIMIHDLCLVFPAPAKAVVYV 40 50 60 70 80 90 980 990 1000 1010 1020 1030 pF1KA0 SDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLKLRAASPIITLVALDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLKLRAASPIITLVALDE 100 110 120 130 140 150 1040 1050 1060 1070 1080 1090 pF1KA0 ALDNYTITFLIRGVAIGQTSLTASVTNKAGQRINSAPQQIEVFPPFRLMPRKVTLLIGAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALDNYTITFLIRGVAIGQTSLTASVTNKAGQRINSAPQQIEVFPPFRLMPRKVTLLIGAT 160 170 180 190 200 210 1100 1110 1120 1130 1140 1150 pF1KA0 MQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSGLVQAVDAETGKVVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSGLVQAVDAETGKVVII 220 230 240 250 260 270 1160 1170 1180 1190 1200 1210 pF1KA0 SQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFSFGNAVPGLTFHWSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFSFGNAVPGLTFHWSVT 280 290 300 310 320 330 1220 1230 1240 1250 1260 1270 pF1KA0 KRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAVDPTSGQLYGLARELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAVDPTSGQLYGLARELS 340 350 360 370 380 390 1280 1290 1300 1310 1320 1330 pF1KA0 DEIQVQVFEKLQLLNPEIEAEQILMSPNSYIKLQTNRDGAASLSYRVLDGPEKVPVVHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEIQVQVFEKLQLLNPEIEAEQILMSPNSYIKLQTNRDGAASLSYRVLDGPEKVPVVHVD 400 410 420 430 440 450 1340 1350 1360 1370 1380 1390 pF1KA0 EKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVSMSPVLHTQNKEALVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVSMSPVLHTQNKEALVA 460 470 480 490 500 510 1400 1410 1420 1430 1440 1450 pF1KA0 VPLGMTVTFTVHFHDNSGDVFHAHSSVLNFATNRDDFVQIGKGPTNNTCVVRTVSVGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPLGMTVTFTVHFHDNSGDVFHAHSSVLNFATNRDDFVQIGKGPTNNTCVVRTVSVGLTL 520 530 540 550 560 570 1460 1470 1480 1490 1500 1510 pF1KA0 LRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTSLEGLSGTWSSSANSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTSLEGLSGTWSSSANSI 580 590 600 610 620 630 1520 1530 1540 1550 1560 1570 pF1KA0 LHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQRIMARHLHPIQTSFQEATAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQRIMARHLHPIQTSFQEATAS 640 650 660 670 680 690 1580 1590 1600 1610 1620 1630 pF1KA0 KVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVFDFPSQDVFTVEPQFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVFDFPSQDVFTVEPQFD 700 710 720 730 740 750 1640 1650 1660 1670 1680 1690 pF1KA0 TALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQVGAEVPFSPGLFADQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQVGAEVPFSPGLFADQ 760 770 780 790 800 810 1700 1710 1720 1730 1740 1750 pF1KA0 AEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFGWPSFITYTVGVSDPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_016 AEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFGWPSFITYTVGVLDPA 820 830 840 850 860 870 1760 1770 1780 1790 1800 1810 pF1KA0 AGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRGPGPYGASLFQHFLDSYQVMFFTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRGPGPYGASLFQHFLDSYQVMFFTLF 880 890 900 910 920 930 1820 1830 1840 1850 1860 1870 pF1KA0 ALLAGTAVMIIAYHTVCTPRDLAVPAALTPRASPGHSPHYFAASSPTSPNALPPARKASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLAGTAVMIIAYHTVCTPRDLAVPAALTPRASPGHSPHYFAASSPTSPNALPPARKASP 940 950 960 970 980 990 1880 pF1KA0 PSGLWSPAYASH :::::::::::: XP_016 PSGLWSPAYASH 1000 1887 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:56:14 2016 done: Wed Nov 2 19:56:17 2016 Total Scan time: 18.280 Total Display time: 0.370 Function used was FASTA [36.3.4 Apr, 2011]