FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0913, 1796 aa 1>>>pF1KA0913 1796 - 1796 aa - 1796 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.1332+/-0.00105; mu= 4.4169+/- 0.064 mean_var=293.6775+/-59.893, 0's: 0 Z-trim(114.0): 17 B-trim: 160 in 1/51 Lambda= 0.074841 statistics sampled from 14541 (14552) to 14541 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.447), width: 16 Scan time: 6.210 The best scores are: opt bits E(32554) CCDS60560.1 ZSWIM8 gene_id:23053|Hs108|chr10 (1837) 7816 858.9 0 CCDS44440.1 ZSWIM8 gene_id:23053|Hs108|chr10 (1842) 7768 853.7 0 CCDS41319.1 ZSWIM5 gene_id:57643|Hs108|chr1 (1185) 550 74.2 3.2e-12 CCDS32924.1 ZSWIM4 gene_id:65249|Hs108|chr19 ( 989) 545 73.6 4.1e-12 CCDS47215.1 ZSWIM6 gene_id:57688|Hs108|chr5 (1215) 536 72.7 9.4e-12 >>CCDS60560.1 ZSWIM8 gene_id:23053|Hs108|chr10 (1837 aa) initn: 6260 init1: 6260 opt: 7816 Z-score: 4570.1 bits: 858.9 E(32554): 0 Smith-Waterman score: 12109; 97.6% identity (97.7% similar) in 1836 aa overlap (2-1796:2-1837) 10 20 30 40 50 60 pF1KA0 MELMFAEWEDGERFSFEDSDRFEEDSLCSFISEAESLCQNWRGWRKQSAGPNSPTGGGGG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MELMFAEWEDGERFSFEDSDRFEEDSLCSFISEAESLCQNWRGWRKQSAGPNSPTGGGGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GGSGGTRMRDGLVIPLVELSAKQVAFHIPFEVVEKVYPPVPEQLQLRIAFWSFPENEEDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GGSGGTRMRDGLVIPLVELSAKQVAFHIPFEVVEKVYPPVPEQLQLRIAFWSFPENEEDI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RLYSCLANGSADEFQRGDQLFRMRAVKDPLQIGFHLSATVVPPQMVPPKGAYNVAVMFDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RLYSCLANGSADEFQRGDQLFRMRAVKDPLQIGFHLSATVVPPQMVPPKGAYNVAVMFDR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 CRVTSCSCTCGAGAKCCTHVVALCLFRIHNASAVCLRAPVSESLSRLQRDQLQKFAQYLI ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: CCDS60 CRVTSCSCTCGAGAKWCTHVVALCLFRIHNASAVCLRAPVSESLSRLQRDQLQKFAQYLI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SELPQQILPTAQRLLDELLSSQSTAINTVCGAPDPTAGPSASDQSTWYLDESTLTDNIKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SELPQQILPTAQRLLDELLSSQSTAINTVCGAPDPTAGPSASDQSTWYLDESTLTDNIKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TLHKFCGPSPVVFSDVNSMYLSSTEPPAAAEWACLLRPLRGREPEGVWNLLSIVREMFKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TLHKFCGPSPVVFSDVNSMYLSSTEPPAAAEWACLLRPLRGREPEGVWNLLSIVREMFKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 RDSNAAPLLEILTDQCLTYEQITGWWYSVRTSASHSSASGHTGRSNGQSEVAAHACASMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RDSNAAPLLEILTDQCLTYEQITGWWYSVRTSASHSSASGHTGRSNGQSEVAAHACASMC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 DEMVTLWRLAVLDPALSPQRRRELCTQLRQWQLKVIENVKRGQHKKTLERLFPGFRPAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DEMVTLWRLAVLDPALSPQRRRELCTQLRQWQLKVIENVKRGQHKKTLERLFPGFRPAVE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 ACYFNWEEAYPLPGVTYSGTDRKLALCWARALPSRPGASRSGGLEESRDRPRPLPTEPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 ACYFNWEEAYPLPGVTYSGTDRKLALCWARALPSRPGASRSGGLEESRDRPRPLPTEPAV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 RPKEPGTKRKGLGEGVPSSQRGPRRLSAEGGDKALHKMGPGGGKAKALGGAGSGSKGSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RPKEPGTKRKGLGEGVPSSQRGPRRLSAEGGDKALHKMGPGGGKAKALGGAGSGSKGSAG 550 560 570 580 590 600 610 620 630 640 pF1KA0 GGSKRRLSSEDSSLEPDLAEMSLDDSSLALGAEASTFGGFPESPPPCP------------ :::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GGSKRRLSSEDSSLEPDLAEMSLDDSSLALGAEASTFGGFPESPPPCPLHGGSRGPSTFL 610 620 630 640 650 660 650 660 670 680 pF1KA0 ---------------------PTASVGPPGLLPGDVCTQDDLPSTDESGNGLPKTKEAAP ::::::::::::::::::::::::::::::::::::::: CCDS60 PEPPDTYEEDGGVYFSEGPEPPTASVGPPGLLPGDVCTQDDLPSTDESGNGLPKTKEAAP 670 680 690 700 710 720 690 700 710 720 730 740 pF1KA0 AVGEEDDDYQAYYLNAQDGAGGEEEKAEGGAGEEHDLFAGLKPLEQESRMEVLFACAEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 AVGEEDDDYQAYYLNAQDGAGGEEEKAEGGAGEEHDLFAGLKPLEQESRMEVLFACAEAL 730 740 750 760 770 780 750 760 770 780 790 800 pF1KA0 HAHGYSSEASRLTVELAQDLLANPPDLKVEPPPAKGKKNKVSTSHQTWVATNTLSKAAFL ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: CCDS60 HAHGYSSEASRLTVELAQDLLANPPDLKVEPPPAKGKKNKVSTSRQTWVATNTLSKAAFL 790 800 810 820 830 840 810 820 830 840 850 860 pF1KA0 LTVLSERPEHHNLAFRVGMFALELQRPPASTKALEVKLAYQESEVAALLKKIPLGPSEMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LTVLSERPEHHNLAFRVGMFALELQRPPASTKALEVKLAYQESEVAALLKKIPLGPSEMS 850 860 870 880 890 900 870 880 890 900 910 920 pF1KA0 TMRCRAEELREGTLCDYRPVLPLMLASFIFDVLCAPGSRPPSRNWNSETPGDEELGFEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TMRCRAEELREGTLCDYRPVLPLMLASFIFDVLCAPGSRPPSRNWNSETPGDEELGFEAA 910 920 930 940 950 960 930 940 950 960 970 980 pF1KA0 VAALGMKTTVSEAEHPLLCEGTRREKGDLALALMITYKDDQAKLKKILDKLLDRESQTHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VAALGMKTTVSEAEHPLLCEGTRREKGDLALALMITYKDDQAKLKKILDKLLDRESQTHK 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KA0 PQTLSSFYSSSRPTTASQRSPSKHGGPSAPGALQPLTSGSAGPAQPGSVAGAGPGPTEGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PQTLSSFYSSSRPTTASQRSPSKHGGPSAPGALQPLTSGSAGPAQPGSVAGAGPGPTEGF 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KA0 TEKNVPESSPHSPCEGLPSEAALTPRPEGKVPSRLALGSRGGYNGRGWGSPGRPKKKHTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TEKNVPESSPHSPCEGLPSEAALTPRPEGKVPSRLALGSRGGYNGRGWGSPGRPKKKHTG 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KA0 MASIDSSAPETTSDSSPTLSRRPLRGGWAPTSWGRGQDSDSISSSSSDSLGSSSSSGSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MASIDSSAPETTSDSSPTLSRRPLRGGWAPTSWGRGQDSDSISSSSSDSLGSSSSSGSRR 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KA0 ASASGGARAKTVEVGRYKGRRPESHAPHVPNQPSEAAAHFYFELAKTVLIKAGGNSSTSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 ASASGGARAKTVEVGRYKGRRPESHAPHVPNQPSEAAAHFYFELAKTVLIKAGGNSSTSI 1210 1220 1230 1240 1250 1260 1230 1240 1250 1260 1270 1280 pF1KA0 FTHPSSSGGHQGPHRNLHLCAFEIGLYALGLHNFVSPNWLSRTYSSHVSWITGQAMEIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 FTHPSSSGGHQGPHRNLHLCAFEIGLYALGLHNFVSPNWLSRTYSSHVSWITGQAMEIGS 1270 1280 1290 1300 1310 1320 1290 1300 1310 1320 1330 1340 pF1KA0 AALTILVECWDGHLTPPEVASLADRASRARDSNMVRAAAELALSCLPHAHALNPNEIQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 AALTILVECWDGHLTPPEVASLADRASRARDSNMVRAAAELALSCLPHAHALNPNEIQRA 1330 1340 1350 1360 1370 1380 1350 1360 1370 1380 1390 1400 pF1KA0 LVQCKEQDNLMLEKACMAVEEAAKGGGVYPEVLFEVAHQWFWLYEQTAGGSSTAREGATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LVQCKEQDNLMLEKACMAVEEAAKGGGVYPEVLFEVAHQWFWLYEQTAGGSSTAREGATS 1390 1400 1410 1420 1430 1440 1410 1420 1430 1440 1450 1460 pF1KA0 CSASGIRAGGEAGRGMPEGRGGPGTEPVTVAAAAVTAAATVVPVISVGSSLYPGPGLGHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 CSASGIRAGGEAGRGMPEGRGGPGTEPVTVAAAAVTAAATVVPVISVGSSLYPGPGLGHG 1450 1460 1470 1480 1490 1500 1470 1480 1490 1500 1510 1520 pF1KA0 HSPGLHPYTALQPHLPCSPQYLTHPAHPAHPMPHMPRPAVFPVPSSAYPQGVHPAFLGAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 HSPGLHPYTALQPHLPCSPQYLTHPAHPAHPMPHMPRPAVFPVPSSAYPQGVHPAFLGAQ 1510 1520 1530 1540 1550 1560 1530 1540 1550 1560 1570 pF1KA0 YPYSVTPPSLAATAVSFPVPSMAPITVHPYHTEPGLPLPTSVA--------LSSVHPAST ::::::::::::::::::::::::::::::::::::::::::: .:::::::: CCDS60 YPYSVTPPSLAATAVSFPVPSMAPITVHPYHTEPGLPLPTSVACELWGQGTVSSVHPAST 1570 1580 1590 1600 1610 1620 1580 1590 1600 1610 1620 1630 pF1KA0 FPAIQGASLPALTTQPSPLVSGGFPPPEEETHSQPVNPHSLHHLHAAYRVGMLALEMLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 FPAIQGASLPALTTQPSPLVSGGFPPPEEETHSQPVNPHSLHHLHAAYRVGMLALEMLGR 1630 1640 1650 1660 1670 1680 1640 1650 1660 1670 1680 1690 pF1KA0 RAHNDHPNNFSRSPPYTDDVKWLLGLAAKLGVNYVHQFCVGAAKGVLSPFVLQEIVMETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RAHNDHPNNFSRSPPYTDDVKWLLGLAAKLGVNYVHQFCVGAAKGVLSPFVLQEIVMETL 1690 1700 1710 1720 1730 1740 1700 1710 1720 1730 1740 1750 pF1KA0 QRLSPAHAHNHLRAPAFHQLVQRCQQAYMQYIHHRLIHLTPADYDDFVNAIRSARSAFCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 QRLSPAHAHNHLRAPAFHQLVQRCQQAYMQYIHHRLIHLTPADYDDFVNAIRSARSAFCL 1750 1760 1770 1780 1790 1800 1760 1770 1780 1790 pF1KA0 TPMGMMQFNDILQNLKRSKQTKELWQRVSLEMATFSP ::::::::::::::::::::::::::::::::::::: CCDS60 TPMGMMQFNDILQNLKRSKQTKELWQRVSLEMATFSP 1810 1820 1830 >>CCDS44440.1 ZSWIM8 gene_id:23053|Hs108|chr10 (1842 aa) initn: 8988 init1: 4556 opt: 7768 Z-score: 4542.1 bits: 853.7 E(32554): 0 Smith-Waterman score: 12058; 97.3% identity (97.4% similar) in 1836 aa overlap (7-1796:7-1842) 10 20 30 40 50 60 pF1KA0 MELMFAEWEDGERFSFEDSDRFEEDSLCSFISEAESLCQNWRGWRKQSAGPNSPTGGGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MELMFAEWEDGERFSFEDSDRFEEDSLCSFISEAESLCQNWRGWRKQSAGPNSPTGGGGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GGSGGTRMRDGLVIPLVELSAKQVAFHIPFEVVEKVYPPVPEQLQLRIAFWSFPENEEDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GGSGGTRMRDGLVIPLVELSAKQVAFHIPFEVVEKVYPPVPEQLQLRIAFWSFPENEEDI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RLYSCLANGSADEFQRGDQLFRMRAVKDPLQIGFHLSATVVPPQMVPPKGAYNVAVMFDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RLYSCLANGSADEFQRGDQLFRMRAVKDPLQIGFHLSATVVPPQMVPPKGAYNVAVMFDR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 CRVTSCSCTCGAGAKCCTHVVALCLFRIHNASAVCLRAPVSESLSRLQRDQLQKFAQYLI ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: CCDS44 CRVTSCSCTCGAGAKWCTHVVALCLFRIHNASAVCLRAPVSESLSRLQRDQLQKFAQYLI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SELPQQILPTAQRLLDELLSSQSTAINTVCGAPDPTAGPSASDQSTWYLDESTLTDNIKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SELPQQILPTAQRLLDELLSSQSTAINTVCGAPDPTAGPSASDQSTWYLDESTLTDNIKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TLHKFCGPSPVVFSDVNSMYLSSTEPPAAAEWACLLRPLRGREPEGVWNLLSIVREMFKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 TLHKFCGPSPVVFSDVNSMYLSSTEPPAAAEWACLLRPLRGREPEGVWNLLSIVREMFKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 RDSNAAPLLEILTDQCLTYEQITGWWYSVRTSASHSSASGHTGRSNGQSEVAAHACASMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RDSNAAPLLEILTDQCLTYEQITGWWYSVRTSASHSSASGHTGRSNGQSEVAAHACASMC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 DEMVTLWRLAVLDPALSPQRRRELCTQLRQWQLKVIENVKRGQHKKTLERLFPGFRPAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DEMVTLWRLAVLDPALSPQRRRELCTQLRQWQLKVIENVKRGQHKKTLERLFPGFRPAVE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 ACYFNWEEAYPLPGVTYSGTDRKLALCWARALPSRPGASRSGGLEESRDRPRPLPTEPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ACYFNWEEAYPLPGVTYSGTDRKLALCWARALPSRPGASRSGGLEESRDRPRPLPTEPAV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 RPKEPGTKRKGLGEGVPSSQRGPRRLSAEGGDKALHKMGPGGGKAKALGGAGSGSKGSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RPKEPGTKRKGLGEGVPSSQRGPRRLSAEGGDKALHKMGPGGGKAKALGGAGSGSKGSAG 550 560 570 580 590 600 610 620 630 640 pF1KA0 GGSKRRLSSEDSSLEPDLAEMSLDDSSLALGAEASTFGGFPESPPPCP------------ :::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GGSKRRLSSEDSSLEPDLAEMSLDDSSLALGAEASTFGGFPESPPPCPLHGGSRGPSTFL 610 620 630 640 650 660 650 660 670 680 pF1KA0 ---------------------PTASVGPPGLLPGDVCTQDDLPSTDESGNGLPKTKEAAP ::::::::::::::::::::::::::::::::::::::: CCDS44 PEPPDTYEEDGGVYFSEGPEPPTASVGPPGLLPGDVCTQDDLPSTDESGNGLPKTKEAAP 670 680 690 700 710 720 690 700 710 720 730 740 pF1KA0 AVGEEDDDYQAYYLNAQDGAGGEEEKAEGGAGEEHDLFAGLKPLEQESRMEVLFACAEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 AVGEEDDDYQAYYLNAQDGAGGEEEKAEGGAGEEHDLFAGLKPLEQESRMEVLFACAEAL 730 740 750 760 770 780 750 760 770 780 790 800 pF1KA0 HAHGYSSEASRLTVELAQDLLANPPDLKVEPPPAKGKKNKVSTSHQTWVATNTLSKAAFL ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: CCDS44 HAHGYSSEASRLTVELAQDLLANPPDLKVEPPPAKGKKNKVSTSRQTWVATNTLSKAAFL 790 800 810 820 830 840 810 820 830 840 850 860 pF1KA0 LTVLSERPEHHNLAFRVGMFALELQRPPASTKALEVKLAYQESEVAALLKKIPLGPSEMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LTVLSERPEHHNLAFRVGMFALELQRPPASTKALEVKLAYQESEVAALLKKIPLGPSEMS 850 860 870 880 890 900 870 880 890 900 910 920 pF1KA0 TMRCRAEELREGTLCDYRPVLPLMLASFIFDVLCAP-----GSRPPSRNWNSETPGDEEL :::::::::::::::::::::::::::::::::::: ::::::::::::::::::: CCDS44 TMRCRAEELREGTLCDYRPVLPLMLASFIFDVLCAPVVSPTGSRPPSRNWNSETPGDEEL 910 920 930 940 950 960 930 940 950 960 970 980 pF1KA0 GFEAAVAALGMKTTVSEAEHPLLCEGTRREKGDLALALMITYKDDQAKLKKILDKLLDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GFEAAVAALGMKTTVSEAEHPLLCEGTRREKGDLALALMITYKDDQAKLKKILDKLLDRE 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KA0 SQTHKPQTLSSFYSSSRPTTASQRSPSKHGGPSAPGALQPLTSGSAGPAQPGSVAGAGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SQTHKPQTLSSFYSSSRPTTASQRSPSKHGGPSAPGALQPLTSGSAGPAQPGSVAGAGPG 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KA0 PTEGFTEKNVPESSPHSPCEGLPSEAALTPRPEGKVPSRLALGSRGGYNGRGWGSPGRPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PTEGFTEKNVPESSPHSPCEGLPSEAALTPRPEGKVPSRLALGSRGGYNGRGWGSPGRPK 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KA0 KKHTGMASIDSSAPETTSDSSPTLSRRPLRGGWAPTSWGRGQDSDSISSSSSDSLGSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KKHTGMASIDSSAPETTSDSSPTLSRRPLRGGWAPTSWGRGQDSDSISSSSSDSLGSSSS 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KA0 SGSRRASASGGARAKTVEVGRYKGRRPESHAPHVPNQPSEAAAHFYFELAKTVLIKAGGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SGSRRASASGGARAKTVEVGRYKGRRPESHAPHVPNQPSEAAAHFYFELAKTVLIKAGGN 1210 1220 1230 1240 1250 1260 1230 1240 1250 1260 1270 1280 pF1KA0 SSTSIFTHPSSSGGHQGPHRNLHLCAFEIGLYALGLHNFVSPNWLSRTYSSHVSWITGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SSTSIFTHPSSSGGHQGPHRNLHLCAFEIGLYALGLHNFVSPNWLSRTYSSHVSWITGQA 1270 1280 1290 1300 1310 1320 1290 1300 1310 1320 1330 1340 pF1KA0 MEIGSAALTILVECWDGHLTPPEVASLADRASRARDSNMVRAAAELALSCLPHAHALNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MEIGSAALTILVECWDGHLTPPEVASLADRASRARDSNMVRAAAELALSCLPHAHALNPN 1330 1340 1350 1360 1370 1380 1350 1360 1370 1380 1390 1400 pF1KA0 EIQRALVQCKEQDNLMLEKACMAVEEAAKGGGVYPEVLFEVAHQWFWLYEQTAGGSSTAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EIQRALVQCKEQDNLMLEKACMAVEEAAKGGGVYPEVLFEVAHQWFWLYEQTAGGSSTAR 1390 1400 1410 1420 1430 1440 1410 1420 1430 1440 1450 1460 pF1KA0 EGATSCSASGIRAGGEAGRGMPEGRGGPGTEPVTVAAAAVTAAATVVPVISVGSSLYPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EGATSCSASGIRAGGEAGRGMPEGRGGPGTEPVTVAAAAVTAAATVVPVISVGSSLYPGP 1450 1460 1470 1480 1490 1500 1470 1480 1490 1500 1510 1520 pF1KA0 GLGHGHSPGLHPYTALQPHLPCSPQYLTHPAHPAHPMPHMPRPAVFPVPSSAYPQGVHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GLGHGHSPGLHPYTALQPHLPCSPQYLTHPAHPAHPMPHMPRPAVFPVPSSAYPQGVHPA 1510 1520 1530 1540 1550 1560 1530 1540 1550 1560 1570 pF1KA0 FLGAQYPYSVTPPSLAATAVSFPVPSMAPITVHPYHTEPGLPLPTSVA--------LSSV :::::::::::::::::::::::::::::::::::::::::::::::: .::: CCDS44 FLGAQYPYSVTPPSLAATAVSFPVPSMAPITVHPYHTEPGLPLPTSVACELWGQGTVSSV 1570 1580 1590 1600 1610 1620 1580 1590 1600 1610 1620 1630 pF1KA0 HPASTFPAIQGASLPALTTQPSPLVSGGFPPPEEETHSQPVNPHSLHHLHAAYRVGMLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 HPASTFPAIQGASLPALTTQPSPLVSGGFPPPEEETHSQPVNPHSLHHLHAAYRVGMLAL 1630 1640 1650 1660 1670 1680 1640 1650 1660 1670 1680 1690 pF1KA0 EMLGRRAHNDHPNNFSRSPPYTDDVKWLLGLAAKLGVNYVHQFCVGAAKGVLSPFVLQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EMLGRRAHNDHPNNFSRSPPYTDDVKWLLGLAAKLGVNYVHQFCVGAAKGVLSPFVLQEI 1690 1700 1710 1720 1730 1740 1700 1710 1720 1730 1740 1750 pF1KA0 VMETLQRLSPAHAHNHLRAPAFHQLVQRCQQAYMQYIHHRLIHLTPADYDDFVNAIRSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VMETLQRLSPAHAHNHLRAPAFHQLVQRCQQAYMQYIHHRLIHLTPADYDDFVNAIRSAR 1750 1760 1770 1780 1790 1800 1760 1770 1780 1790 pF1KA0 SAFCLTPMGMMQFNDILQNLKRSKQTKELWQRVSLEMATFSP :::::::::::::::::::::::::::::::::::::::::: CCDS44 SAFCLTPMGMMQFNDILQNLKRSKQTKELWQRVSLEMATFSP 1810 1820 1830 1840 >>CCDS41319.1 ZSWIM5 gene_id:57643|Hs108|chr1 (1185 aa) initn: 770 init1: 253 opt: 550 Z-score: 332.8 bits: 74.2 E(32554): 3.2e-12 Smith-Waterman score: 661; 31.4% identity (53.0% similar) in 513 aa overlap (32-473:17-470) 10 20 30 40 50 pF1KA0 ELMFAEWEDGERFSFEDSDRFEEDSLCSFISEAESLCQNWRGWRKQSAGPNSPTG--GGG : :. : .: . :. : . : ::: CCDS41 MADGGEREELLSPSPVSPAKRQC-SWPS--PQAHHPRGSPGAAGGG 10 20 30 40 60 70 80 90 100 110 pF1KA0 GGGSGGTRMRDGL---VIP--LVELSAKQVAFHIPFEVVEKVYPPVPEQLQLRIAFWSFP .:: :.. . : . : :.. .:: :: . .: ::. . .:: .: ::..:::: CCDS41 AGGVGSSCLVLGARPHLQPDSLLDCAAKTVAEKWAYERVEERFERIPEPVQRRIVYWSFP 50 60 70 80 90 100 120 130 pF1KA0 ENEEDIRLYSCL----------ANGSADE------------------------------- .::..: .:: . :.:.: CCDS41 RNEREICMYSSFQYRGGPGAGAAGGAAGASPAEEGPQPPPGAAAPAGSAPGGVAAGASPG 110 120 130 140 150 160 140 150 160 170 pF1KA0 ----------------FQRGDQLFRMRAVKDPLQIGFHLSATVVP-PQMVPPKGAYNVAV :.:: .:. .:.. ::.:::::.::. : .:.::. CCDS41 LGAGAGAAGCGGEGLPFRRGIRLLDSGSVENVLQVGFHLSGTVTELATASEPAVTYKVAI 170 180 190 200 210 220 180 190 200 210 220 230 pF1KA0 MFDRCRVTSCSCTCGAGAKC-CTHVVALCLFRIHNASAVCLRAPVSESLSRLQRDQLQKF ::::..:: .: :: :.::::: :.::.. . : :: :.::.: ...::::::: CCDS41 SFDRCKITSVTCGCGNKDIFYCAHVVALSLYRIRKPDQVKLRLPISETLFQMNRDQLQKF 230 240 250 260 270 280 240 250 260 270 280 290 pF1KA0 AQYLISELPQQILPTAQRLLDELLSSQSTAINTVCGAPDPTAGPSASDQSTWYLDESTLT ::::. ..:::::.: ::.:::.: :: : :::::::: : .:.. :.::: . CCDS41 IQYLITAHHTEVLPTAQKLADEILSSNSE-INQVNGAPDPTAGASIDDENCWHLDEEQVK 290 300 310 320 330 340 300 310 320 330 340 350 pF1KA0 DNIKKTLHK--FCGPSPVVFSDVNSMYLSSTEPPAAAEWACLLRPLRGREPEGVWNLLSI ...: : . .:: . ...:::. . CCDS41 EQVKLFLSQGGYCGSG----KQLNSMFAK------------------------------- 350 360 360 370 380 390 400 410 pF1KA0 VREMFKRRDSNAAPLLEILTDQCLTYEQITGWWYSVRTSASHSSASGHTGRSNGQSEVAA ::::.. ::::.: .: ..:.: .. ..: : :..: . . CCDS41 VREMLRMRDSNGARMLTLITEQFVADPRLTLW------------------RQQGTN--MT 370 380 390 400 420 430 440 450 460 470 pF1KA0 HACASMCDEMVTLWRLAVLDPALSPQRRRELCTQLRQWQ-LKV--IENVKRGQHKKTLER : .. ::. .:: .:.: . ... ::..:. : : .:. . :.. .. CCDS41 DKCRQLWDELGALWVCIILNPHCKLEEKSCWLQQLQKWSDLDVCPLEDGNYGHELPNITN 410 420 430 440 450 460 480 490 500 510 520 530 pF1KA0 LFPGFRPAVEACYFNWEEAYPLPGVTYSGTDRKLALCWARALPSRPGASRSGGLEESRDR .: CCDS41 ALPQSAIHSPDSLSRPRRTVFTRAIEGRELHWQDSHLQRIISSDVYTAPACQRESERLLF 470 480 490 500 510 520 >>CCDS32924.1 ZSWIM4 gene_id:65249|Hs108|chr19 (989 aa) initn: 856 init1: 247 opt: 545 Z-score: 330.9 bits: 73.6 E(32554): 4.1e-12 Smith-Waterman score: 761; 36.3% identity (58.5% similar) in 446 aa overlap (46-480:7-394) 20 30 40 50 60 70 pF1KA0 FEDSDRFEEDSLCSFISEAESLCQNWRGWRKQSAG-PNSPTGGGGGGGSGGTRMRDGLVI :.: : : .: .:.:.. : : CCDS32 MEPPAAKRSRGCPAGPEERDAGAGAARGRGRPE--- 10 20 30 80 90 100 110 120 130 pF1KA0 PLVELSAKQVAFHIPFEVVEKVYPPVPEQLQLRIAFWSFPENEEDIRLYSCLA----NGS :..::::.:: :: ::. . ::: .: ::.:::::..:..: .:: :. .: CCDS32 ALLDLSAKRVAESWAFEQVEERFSRVPEPVQKRIVFWSFPRSEREICMYSSLGYPPPEGE 40 50 60 70 80 90 140 150 160 170 180 pF1KA0 ADE---FQRGDQLFRMRAVKDPLQIGFHLSATVVPPQMVP--PKGAYNVAVMFDRCRVTS : : :: .:.. :: ::.:::::... : : :. :.:.. ::::..:: CCDS32 HDARVPFTRGLHLLQSGAVDRVLQVGFHLSGNIREPGS-PGEPERLYHVSISFDRCKITS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA0 CSCTCGAGAKC-CTHVVALCLFRIHNASAVCLRAPVSESLSRLQRDQLQKFAQYLISELP :: : :.::::: :.::..: : :: :.::.::...:::::::.::::: CCDS32 VSCGCDNRDLFYCAHVVALSLYRIRHAHQVELRLPISETLSQMNRDQLQKFVQYLISAHH 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA0 QQILPTAQRLLDELLSSQSTAINTVCGAPDPTAGPSASDQSTWYLDESTLTDNIKKTLHK ..::::::: ::.: .. :: : :::::::: . : . :.::: . ...:. : CCDS32 TEVLPTAQRLADEILL-LGSEINLVNGAPDPTAGAGIEDANCWHLDEEQIQEQVKQLLS- 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA0 FCGPSPVVFSDVNSMYLSSTEPPAAAEWACLLRPLRGREPEGVWNLLSIVREMFKRRDSN :. : .... :: ...: ::::.. :::: CCDS32 ------------NGGYYGASQQ---------LR-----------SMFSKVREMLRMRDSN 280 290 370 380 390 400 410 420 pF1KA0 AAPLLEILTDQCLTYEQITGWWYSVRTSASHSSASGHTGRSNGQSEVAAHACASMCDEMV .: .: ..:.: : ... : .....: : . : .. ::. CCDS32 GARMLILMTEQFLQDTRLALW---------RQQGAGMTDK-----------CRQLWDELG 300 310 320 330 430 440 450 460 470 480 pF1KA0 TLWRLAVLDPALSPQRRRELCTQLRQWQLKVIENVKRGQHKKTLERLFPGFRPAVEACYF .:: .::.: .:..: : .:. . ...:... : : . :: : CCDS32 ALWVCVVLSPHCKPEERAGWLQLLSRWDKLDVCPLEEGNYSFDGPSLQPTMAPAPELLQK 340 350 360 370 380 390 490 500 510 520 530 540 pF1KA0 NWEEAYPLPGVTYSGTDRKLALCWARALPSRPGASRSGGLEESRDRPRPLPTEPAVRPKE CCDS32 GSTCITNTEGWVGHPLDPIGCLCRALLEACRLEEETLTLYPDSGPEKRKVAYQHVPVPGS 400 410 420 430 440 450 >>CCDS47215.1 ZSWIM6 gene_id:57688|Hs108|chr5 (1215 aa) initn: 659 init1: 240 opt: 536 Z-score: 324.5 bits: 72.7 E(32554): 9.4e-12 Smith-Waterman score: 624; 29.1% identity (51.2% similar) in 537 aa overlap (49-490:48-530) 20 30 40 50 60 70 pF1KA0 SDRFEEDSLCSFISEAESLCQNWRGWRKQSAGPNSPTGGGGGGGSGGTRMRDGLVIP--L :: . ... :::.. : : : CCDS47 PGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESL 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 VELSAKQVAFHIPFEVVEKVYPPVPEQLQLRIAFWSFPENEEDIRLYSCL---------- ....:..:: . ::. ::. . .:: .: ::..::::..:..: .:: . CCDS47 LDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGGAAGGP 80 90 100 110 120 130 130 pF1KA0 -------------------------------------------------------ANGSA : :.: CCDS47 GDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAA 140 150 160 170 180 190 140 150 160 170 180 pF1KA0 D-------EFQRGDQLFRMRAVKDPLQIGFHLSATVVPPQM-VPPKGAYNVAVMFDRCRV : :.:: :.. : . ::.:::::.::. : . :. . :::. ::::.. CCDS47 DGGDETRLPFRRGIALLESGCVDNVLQVGFHLSGTVTEPAIQSEPETVCNVAISFDRCKI 200 210 220 230 240 250 190 200 210 220 230 240 pF1KA0 TSCSCTCGAGAKC-CTHVVALCLFRIHNASAVCLRAPVSESLSRLQRDQLQKFAQYLISE :: .:.:: :.::::: :.::.. . : :. :.::.: ...:::::::.::::. CCDS47 TSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITV 260 270 280 290 300 310 250 260 270 280 290 300 pF1KA0 LPQQILPTAQRLLDELLSSQSTAINTVCGAPDPTAGPSASDQSTWYLDESTLTDNIKKTL ..:::::.: ::.:: :.. :: : :::::::: : .:.. :.::: . ...: CCDS47 HHTEVLPTAQKLADEILS-QNSEINQVHGAPDPTAGASIDDENCWHLDEEQVQEQVK--- 320 330 340 350 360 370 310 320 330 340 350 360 pF1KA0 HKFCGPSPVVFSDVNSMYLSSTEPPAAAEWACLLRPLRGREPEGVWNLLSIVREMFKRRD ..::. .... :: .. ::::.: :: CCDS47 ----------------LFLSQGGYHGSGKQLNLL--------------FAKVREMLKMRD 380 390 400 370 380 390 400 410 420 pF1KA0 SNAAPLLEILTDQCLTYEQITGWWYSVRTSASHSSASGHTGRSNGQSEVAAHACASMCDE ::.: .: ..:.: .. ... : :..: . . . .. :: CCDS47 SNGARMLTLITEQFMADPRLSLW------------------RQQGTAMTDKY--RQLWDE 410 420 430 440 430 440 450 460 470 pF1KA0 MVTLWRLAVLDPALSPQRRRELCTQLRQWQLKVIENVKRGQHKKTLERLFPGF------- . .:: ::.: . ... ::..:. . . :.: . : : .. CCDS47 LGALWMCIVLNPHCKLEQKASWLKQLKKWNSVDVCPWEDGNHGSELPNLTNALPQGANAN 450 460 470 480 490 500 480 490 500 510 520 pF1KA0 -----RP-------AVEACYFNWEEAYPLPGVTYSGTDRKLALCWARALPSRPGASRSGG :: :.::: ..:.... CCDS47 QDSSNRPHRTVFTRAIEACDLHWQDSHLQHIISSDLYTNYCYHDDTENSLFDSRGWPLWH 510 520 530 540 550 560 1796 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 19:51:56 2016 done: Thu Nov 3 19:51:57 2016 Total Scan time: 6.210 Total Display time: 0.290 Function used was FASTA [36.3.4 Apr, 2011]