FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0914, 669 aa 1>>>pF1KA0914 669 - 669 aa - 669 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4416+/-0.000423; mu= 5.6010+/- 0.026 mean_var=194.2024+/-38.995, 0's: 0 Z-trim(117.5): 59 B-trim: 38 in 1/54 Lambda= 0.092034 statistics sampled from 29575 (29634) to 29575 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.347), width: 16 Scan time: 9.730 The best scores are: opt bits E(85289) NP_001252508 (OMIM: 613299) protein FAM13A isoform ( 669) 4418 599.7 1.1e-170 XP_005262740 (OMIM: 613299) PREDICTED: protein FAM ( 995) 4355 591.5 5.1e-168 XP_016863123 (OMIM: 613299) PREDICTED: protein FAM ( 655) 4258 578.4 2.8e-164 XP_016863117 (OMIM: 613299) PREDICTED: protein FAM ( 772) 4258 578.5 3.1e-164 XP_016863113 (OMIM: 613299) PREDICTED: protein FAM ( 981) 4258 578.6 3.8e-164 NP_001015045 (OMIM: 613299) protein FAM13A isoform ( 697) 3492 476.8 1.2e-133 XP_016863122 (OMIM: 613299) PREDICTED: protein FAM ( 702) 3429 468.4 4e-131 XP_016863118 (OMIM: 613299) PREDICTED: protein FAM ( 751) 3429 468.4 4.2e-131 XP_016863119 (OMIM: 613299) PREDICTED: protein FAM ( 751) 3429 468.4 4.2e-131 XP_005262741 (OMIM: 613299) PREDICTED: protein FAM ( 814) 3429 468.4 4.5e-131 XP_016863116 (OMIM: 613299) PREDICTED: protein FAM ( 814) 3429 468.4 4.5e-131 XP_006714120 (OMIM: 613299) PREDICTED: protein FAM ( 834) 3429 468.5 4.6e-131 XP_011529820 (OMIM: 613299) PREDICTED: protein FAM ( 837) 3429 468.5 4.6e-131 XP_011529821 (OMIM: 613299) PREDICTED: protein FAM ( 837) 3429 468.5 4.6e-131 XP_016863115 (OMIM: 613299) PREDICTED: protein FAM ( 846) 3429 468.5 4.6e-131 XP_016863114 (OMIM: 613299) PREDICTED: protein FAM ( 968) 3429 468.5 5.1e-131 XP_011529819 (OMIM: 613299) PREDICTED: protein FAM ( 995) 3429 468.5 5.2e-131 XP_005262739 (OMIM: 613299) PREDICTED: protein FAM (1003) 3429 468.5 5.3e-131 NP_055698 (OMIM: 613299) protein FAM13A isoform a (1023) 3429 468.5 5.3e-131 XP_011529818 (OMIM: 613299) PREDICTED: protein FAM (1023) 3429 468.5 5.3e-131 NP_001252507 (OMIM: 613299) protein FAM13A isoform ( 683) 3332 455.5 2.9e-127 XP_016863121 (OMIM: 613299) PREDICTED: protein FAM ( 737) 3332 455.5 3.1e-127 XP_016863120 (OMIM: 613299) PREDICTED: protein FAM ( 737) 3332 455.5 3.1e-127 XP_005262738 (OMIM: 613299) PREDICTED: protein FAM (1009) 3332 455.6 4e-127 NP_001252509 (OMIM: 613299) protein FAM13A isoform ( 669) 3239 443.2 1.5e-123 XP_006714712 (OMIM: 609371) PREDICTED: protein FAM ( 819) 1132 163.5 2.9e-39 XP_011541751 (OMIM: 609371) PREDICTED: protein FAM ( 937) 1132 163.5 3.2e-39 XP_006714711 (OMIM: 609371) PREDICTED: protein FAM ( 937) 1132 163.5 3.2e-39 XP_006714710 (OMIM: 609371) PREDICTED: protein FAM ( 937) 1132 163.5 3.2e-39 XP_011541750 (OMIM: 609371) PREDICTED: protein FAM ( 937) 1132 163.5 3.2e-39 XP_011541752 (OMIM: 609371) PREDICTED: protein FAM ( 937) 1132 163.5 3.2e-39 XP_016865040 (OMIM: 609371) PREDICTED: protein FAM ( 797) 1089 157.7 1.5e-37 XP_016865039 (OMIM: 609371) PREDICTED: protein FAM ( 915) 1089 157.8 1.7e-37 NP_057687 (OMIM: 609371) protein FAM13B isoform 1 ( 915) 1089 157.8 1.7e-37 XP_016865038 (OMIM: 609371) PREDICTED: protein FAM ( 915) 1089 157.8 1.7e-37 NP_001095271 (OMIM: 609371) protein FAM13B isoform ( 791) 707 107.0 2.7e-22 NP_001095270 (OMIM: 609371) protein FAM13B isoform ( 887) 707 107.1 3e-22 XP_005272064 (OMIM: 609371) PREDICTED: protein FAM ( 909) 707 107.1 3.1e-22 >>NP_001252508 (OMIM: 613299) protein FAM13A isoform d [ (669 aa) initn: 4418 init1: 4418 opt: 4418 Z-score: 3185.1 bits: 599.7 E(85289): 1.1e-170 Smith-Waterman score: 4418; 100.0% identity (100.0% similar) in 669 aa overlap (1-669:1-669) 10 20 30 40 50 60 pF1KA0 MACEIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MACEIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 WMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 GSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 ALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIEEEEGSEDDSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIEEEEGSEDDSNV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 KPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 LQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLIS 610 620 630 640 650 660 pF1KA0 KRDTDSKSM ::::::::: NP_001 KRDTDSKSM >>XP_005262740 (OMIM: 613299) PREDICTED: protein FAM13A (995 aa) initn: 4353 init1: 4353 opt: 4355 Z-score: 3137.5 bits: 591.5 E(85289): 5.1e-168 Smith-Waterman score: 4355; 98.8% identity (99.6% similar) in 669 aa overlap (1-669:329-995) 10 20 30 pF1KA0 MACEIMPLQSSQEDERPLSPFYLSAHVPQV .. ...: ::::::::::::::::::::: XP_005 PELSDGIPQLSLRLSYRKACLEDMNSAEGAISAKLVP--SSQEDERPLSPFYLSAHVPQV 300 310 320 330 340 350 40 50 60 70 80 90 pF1KA0 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD 360 370 380 390 400 410 100 110 120 130 140 150 pF1KA0 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS 420 430 440 450 460 470 160 170 180 190 200 210 pF1KA0 ELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHP 480 490 500 510 520 530 220 230 240 250 260 270 pF1KA0 SLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHL 540 550 560 570 580 590 280 290 300 310 320 330 pF1KA0 SPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSY 600 610 620 630 640 650 340 350 360 370 380 390 pF1KA0 DDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR 660 670 680 690 700 710 400 410 420 430 440 450 pF1KA0 RQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESI 720 730 740 750 760 770 460 470 480 490 500 510 pF1KA0 QRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYD 780 790 800 810 820 830 520 530 540 550 560 570 pF1KA0 RYRLVKQILSRANTIPIIEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RYRLVKQILSRANTIPIIEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFIS 840 850 860 870 880 890 580 590 600 610 620 630 pF1KA0 PMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNV 900 910 920 930 940 950 640 650 660 pF1KA0 QKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM ::::::::::::::::::::::::::::::::::::::: XP_005 QKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM 960 970 980 990 >>XP_016863123 (OMIM: 613299) PREDICTED: protein FAM13A (655 aa) initn: 4258 init1: 4258 opt: 4258 Z-score: 3070.4 bits: 578.4 E(85289): 2.8e-164 Smith-Waterman score: 4285; 97.9% identity (97.9% similar) in 669 aa overlap (1-669:1-655) 10 20 30 40 50 60 pF1KA0 MACEIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGG :::::::::: :::::::::::::::::::::::::::::::::::: XP_016 MACEIMPLQS--------------AHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGG 10 20 30 40 70 80 90 100 110 120 pF1KA0 QSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNT 50 60 70 80 90 100 130 140 150 160 170 180 pF1KA0 QEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFE 110 120 130 140 150 160 190 200 210 220 230 240 pF1KA0 WMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLT 170 180 190 200 210 220 250 260 270 280 290 300 pF1KA0 ALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQS 230 240 250 260 270 280 310 320 330 340 350 360 pF1KA0 RQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRF 290 300 310 320 330 340 370 380 390 400 410 420 pF1KA0 EEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSF 350 360 370 380 390 400 430 440 450 460 470 480 pF1KA0 GSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KA0 ALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIEEEEGSEDDSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIEEEEGSEDDSNV 470 480 490 500 510 520 550 560 570 580 590 600 pF1KA0 KPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEH 530 540 550 560 570 580 610 620 630 640 650 660 pF1KA0 LQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLIS 590 600 610 620 630 640 pF1KA0 KRDTDSKSM ::::::::: XP_016 KRDTDSKSM 650 >>XP_016863117 (OMIM: 613299) PREDICTED: protein FAM13A (772 aa) initn: 4258 init1: 4258 opt: 4258 Z-score: 3069.4 bits: 578.5 E(85289): 3.1e-164 Smith-Waterman score: 4258; 100.0% identity (100.0% similar) in 646 aa overlap (24-669:127-772) 10 20 30 40 50 pF1KA0 MACEIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLF :::::::::::::::::::::::::::::: XP_016 PQLSLRLSYRKACLEDMNSAEGAISAKLVPSAHVPQVSNVSATGELLERTIRSAVEQHLF 100 110 120 130 140 150 60 70 80 90 100 110 pF1KA0 DVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHL 160 170 180 190 200 210 120 130 140 150 160 170 pF1KA0 DDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHER 220 230 240 250 260 270 180 190 200 210 220 230 pF1KA0 TGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSE 280 290 300 310 320 330 240 250 260 270 280 290 pF1KA0 VPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPR 340 350 360 370 380 390 300 310 320 330 340 350 pF1KA0 FYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKI 400 410 420 430 440 450 360 370 380 390 400 410 pF1KA0 RKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRS 460 470 480 490 500 510 420 430 440 450 460 470 pF1KA0 NTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKD 520 530 540 550 560 570 480 490 500 510 520 530 pF1KA0 QIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIEEEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIEEEEG 580 590 600 610 620 630 540 550 560 570 580 590 pF1KA0 SEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAAS 640 650 660 670 680 690 600 610 620 630 640 650 pF1KA0 IPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLR 700 710 720 730 740 750 660 pF1KA0 LLEVLISKRDTDSKSM :::::::::::::::: XP_016 LLEVLISKRDTDSKSM 760 770 >>XP_016863113 (OMIM: 613299) PREDICTED: protein FAM13A (981 aa) initn: 4258 init1: 4258 opt: 4258 Z-score: 3068.0 bits: 578.6 E(85289): 3.8e-164 Smith-Waterman score: 4258; 100.0% identity (100.0% similar) in 646 aa overlap (24-669:336-981) 10 20 30 40 50 pF1KA0 MACEIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLF :::::::::::::::::::::::::::::: XP_016 PQLSLRLSYRKACLEDMNSAEGAISAKLVPSAHVPQVSNVSATGELLERTIRSAVEQHLF 310 320 330 340 350 360 60 70 80 90 100 110 pF1KA0 DVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHL 370 380 390 400 410 420 120 130 140 150 160 170 pF1KA0 DDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHER 430 440 450 460 470 480 180 190 200 210 220 230 pF1KA0 TGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSE 490 500 510 520 530 540 240 250 260 270 280 290 pF1KA0 VPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPR 550 560 570 580 590 600 300 310 320 330 340 350 pF1KA0 FYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKI 610 620 630 640 650 660 360 370 380 390 400 410 pF1KA0 RKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRS 670 680 690 700 710 720 420 430 440 450 460 470 pF1KA0 NTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKD 730 740 750 760 770 780 480 490 500 510 520 530 pF1KA0 QIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIEEEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIEEEEG 790 800 810 820 830 840 540 550 560 570 580 590 pF1KA0 SEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAAS 850 860 870 880 890 900 600 610 620 630 640 650 pF1KA0 IPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLR 910 920 930 940 950 960 660 pF1KA0 LLEVLISKRDTDSKSM :::::::::::::::: XP_016 LLEVLISKRDTDSKSM 970 980 >>NP_001015045 (OMIM: 613299) protein FAM13A isoform b [ (697 aa) initn: 3486 init1: 3486 opt: 3492 Z-score: 2520.4 bits: 476.8 E(85289): 1.2e-133 Smith-Waterman score: 4352; 96.0% identity (96.0% similar) in 697 aa overlap (1-669:1-697) 10 20 30 40 50 60 pF1KA0 MACEIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MACEIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 WMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 GSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKV 430 440 450 460 470 480 490 500 510 520 pF1KA0 ALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPII------------ :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLL 490 500 510 520 530 540 530 540 550 560 570 pF1KA0 ----------------EEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPM :::::::::::::::::::::::::::::::::::::::::::: NP_001 QPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPM 550 560 570 580 590 600 580 590 600 610 620 630 pF1KA0 DDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQK 610 620 630 640 650 660 640 650 660 pF1KA0 EDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM ::::::::::::::::::::::::::::::::::::: NP_001 EDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM 670 680 690 >>XP_016863122 (OMIM: 613299) PREDICTED: protein FAM13A (702 aa) initn: 3421 init1: 3421 opt: 3429 Z-score: 2475.1 bits: 468.4 E(85289): 4e-131 Smith-Waterman score: 4289; 94.8% identity (95.6% similar) in 697 aa overlap (1-669:8-702) 10 20 30 40 50 pF1KA0 MACEIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLF .. ...: :::::::::::::::::::::::::::::::::::::::::::: XP_016 MNSAEGAISAKLVP--SSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLF 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 DVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 DDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHER 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 TGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 VPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA0 FYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKI 300 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 RKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRS 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 NTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKD 420 430 440 450 460 470 480 490 500 510 520 pF1KA0 QIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPII----- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSS 480 490 500 510 520 530 530 540 550 560 pF1KA0 -----------------------EEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDA ::::::::::::::::::::::::::::::::::::: XP_016 KRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDA 540 550 560 570 580 590 570 580 590 600 610 620 pF1KA0 DGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQ 600 610 620 630 640 650 630 640 650 660 pF1KA0 NGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM :::::::::::::::::::::::::::::::::::::::::::: XP_016 NGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM 660 670 680 690 700 >>XP_016863118 (OMIM: 613299) PREDICTED: protein FAM13A (751 aa) initn: 3421 init1: 3421 opt: 3429 Z-score: 2474.7 bits: 468.4 E(85289): 4.2e-131 Smith-Waterman score: 4289; 94.8% identity (95.6% similar) in 697 aa overlap (1-669:57-751) 10 20 30 pF1KA0 MACEIMPLQSSQEDERPLSPFYLSAHVPQV .. ...: ::::::::::::::::::::: XP_016 PELSDGIPQLSLRLSYRKACLEDMNSAEGAISAKLVP--SSQEDERPLSPFYLSAHVPQV 30 40 50 60 70 80 40 50 60 70 80 90 pF1KA0 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD 90 100 110 120 130 140 100 110 120 130 140 150 pF1KA0 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS 150 160 170 180 190 200 160 170 180 190 200 210 pF1KA0 ELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHP 210 220 230 240 250 260 220 230 240 250 260 270 pF1KA0 SLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHL 270 280 290 300 310 320 280 290 300 310 320 330 pF1KA0 SPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSY 330 340 350 360 370 380 340 350 360 370 380 390 pF1KA0 DDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR 390 400 410 420 430 440 400 410 420 430 440 450 pF1KA0 RQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESI 450 460 470 480 490 500 460 470 480 490 500 510 pF1KA0 QRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYD 510 520 530 540 550 560 520 530 540 pF1KA0 RYRLVKQILSRANTIPII----------------------------EEEEGSEDDSNVKP :::::::::::::::::: :::::::::::::: XP_016 RYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKP 570 580 590 600 610 620 550 560 570 580 590 600 pF1KA0 DFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQ 630 640 650 660 670 680 610 620 630 640 650 660 pF1KA0 EMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKR 690 700 710 720 730 740 pF1KA0 DTDSKSM ::::::: XP_016 DTDSKSM 750 >>XP_016863119 (OMIM: 613299) PREDICTED: protein FAM13A (751 aa) initn: 3421 init1: 3421 opt: 3429 Z-score: 2474.7 bits: 468.4 E(85289): 4.2e-131 Smith-Waterman score: 4289; 94.8% identity (95.6% similar) in 697 aa overlap (1-669:57-751) 10 20 30 pF1KA0 MACEIMPLQSSQEDERPLSPFYLSAHVPQV .. ...: ::::::::::::::::::::: XP_016 PELSDGIPQLSLRLSYRKACLEDMNSAEGAISAKLVP--SSQEDERPLSPFYLSAHVPQV 30 40 50 60 70 80 40 50 60 70 80 90 pF1KA0 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD 90 100 110 120 130 140 100 110 120 130 140 150 pF1KA0 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS 150 160 170 180 190 200 160 170 180 190 200 210 pF1KA0 ELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHP 210 220 230 240 250 260 220 230 240 250 260 270 pF1KA0 SLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHL 270 280 290 300 310 320 280 290 300 310 320 330 pF1KA0 SPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSY 330 340 350 360 370 380 340 350 360 370 380 390 pF1KA0 DDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR 390 400 410 420 430 440 400 410 420 430 440 450 pF1KA0 RQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESI 450 460 470 480 490 500 460 470 480 490 500 510 pF1KA0 QRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYD 510 520 530 540 550 560 520 530 540 pF1KA0 RYRLVKQILSRANTIPII----------------------------EEEEGSEDDSNVKP :::::::::::::::::: :::::::::::::: XP_016 RYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKP 570 580 590 600 610 620 550 560 570 580 590 600 pF1KA0 DFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQ 630 640 650 660 670 680 610 620 630 640 650 660 pF1KA0 EMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKR 690 700 710 720 730 740 pF1KA0 DTDSKSM ::::::: XP_016 DTDSKSM 750 >>XP_005262741 (OMIM: 613299) PREDICTED: protein FAM13A (814 aa) initn: 3421 init1: 3421 opt: 3429 Z-score: 2474.2 bits: 468.4 E(85289): 4.5e-131 Smith-Waterman score: 4289; 94.8% identity (95.6% similar) in 697 aa overlap (1-669:120-814) 10 20 30 pF1KA0 MACEIMPLQSSQEDERPLSPFYLSAHVPQV .. ...: ::::::::::::::::::::: XP_005 PELSDGIPQLSLRLSYRKACLEDMNSAEGAISAKLVP--SSQEDERPLSPFYLSAHVPQV 90 100 110 120 130 140 40 50 60 70 80 90 pF1KA0 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD 150 160 170 180 190 200 100 110 120 130 140 150 pF1KA0 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS 210 220 230 240 250 260 160 170 180 190 200 210 pF1KA0 ELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHP 270 280 290 300 310 320 220 230 240 250 260 270 pF1KA0 SLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHL 330 340 350 360 370 380 280 290 300 310 320 330 pF1KA0 SPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSY 390 400 410 420 430 440 340 350 360 370 380 390 pF1KA0 DDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR 450 460 470 480 490 500 400 410 420 430 440 450 pF1KA0 RQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESI 510 520 530 540 550 560 460 470 480 490 500 510 pF1KA0 QRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYD 570 580 590 600 610 620 520 530 540 pF1KA0 RYRLVKQILSRANTIPII----------------------------EEEEGSEDDSNVKP :::::::::::::::::: :::::::::::::: XP_005 RYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKP 630 640 650 660 670 680 550 560 570 580 590 600 pF1KA0 DFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQ 690 700 710 720 730 740 610 620 630 640 650 660 pF1KA0 EMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKR 750 760 770 780 790 800 pF1KA0 DTDSKSM ::::::: XP_005 DTDSKSM 810 669 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:57:03 2016 done: Wed Nov 2 19:57:05 2016 Total Scan time: 9.730 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]