FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0937, 619 aa 1>>>pF1KA0937 619 - 619 aa - 619 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.1444+/-0.000868; mu= 2.3411+/- 0.052 mean_var=206.6914+/-41.859, 0's: 0 Z-trim(114.1): 15 B-trim: 151 in 1/53 Lambda= 0.089210 statistics sampled from 14698 (14710) to 14698 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.452), width: 16 Scan time: 3.850 The best scores are: opt bits E(32554) CCDS44612.1 DTX4 gene_id:23220|Hs108|chr11 ( 619) 4262 561.2 1.4e-159 CCDS76408.1 DTX4 gene_id:23220|Hs108|chr11 ( 513) 3508 464.1 2e-130 CCDS9164.1 DTX1 gene_id:1840|Hs108|chr12 ( 620) 1871 253.5 6.3e-67 CCDS5587.1 DTX2 gene_id:113878|Hs108|chr7 ( 622) 1316 182.0 2e-45 CCDS43605.1 DTX2 gene_id:113878|Hs108|chr7 ( 575) 1153 161.0 3.9e-39 CCDS3015.1 DTX3L gene_id:151636|Hs108|chr3 ( 740) 508 78.1 4.6e-14 CCDS41800.1 DTX3 gene_id:196403|Hs108|chr12 ( 347) 424 67.1 4.5e-11 CCDS66410.1 DTX3 gene_id:196403|Hs108|chr12 ( 350) 424 67.1 4.5e-11 >>CCDS44612.1 DTX4 gene_id:23220|Hs108|chr11 (619 aa) initn: 4262 init1: 4262 opt: 4262 Z-score: 2978.2 bits: 561.2 E(32554): 1.4e-159 Smith-Waterman score: 4262; 100.0% identity (100.0% similar) in 619 aa overlap (1-619:1-619) 10 20 30 40 50 60 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRAGGSVVLGQVDSRLAPYIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRAGGSVVLGQVDSRLAPYIIDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGSWTPYDMEVGITIQHAYEKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 QSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGSWTPYDMEVGITIQHAYEKQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 HPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 HPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ATSPPMSPCSCPQCVLVMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ATSPPMSPCSCPQCVLVMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 AIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 AIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VSKSEIKSIPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VSKSEIKSIPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 GYKGPQPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GYKGPQPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 RKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNV 550 560 570 580 590 600 610 pF1KA0 LAELAAQGISEDSTAQEKD ::::::::::::::::::: CCDS44 LAELAAQGISEDSTAQEKD 610 >>CCDS76408.1 DTX4 gene_id:23220|Hs108|chr11 (513 aa) initn: 3508 init1: 3508 opt: 3508 Z-score: 2454.9 bits: 464.1 E(32554): 2e-130 Smith-Waterman score: 3508; 100.0% identity (100.0% similar) in 513 aa overlap (107-619:1-513) 80 90 100 110 120 130 pF1KA0 RRNYYDPSSAPGKGVVWEWENDNGSWTPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVID :::::::::::::::::::::::::::::: CCDS76 MEVGITIQHAYEKQHPWIDLTSIGFSYVID 10 20 30 140 150 160 170 180 190 pF1KA0 FNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 FNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KA0 VMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 VMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KA0 VIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 VIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTV 160 170 180 190 200 210 320 330 340 350 360 370 pF1KA0 PVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 PVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KA0 RKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKGPQPTVKPDLVGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 RKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKGPQPTVKPDLVGK 280 290 300 310 320 330 440 450 460 470 480 490 pF1KA0 LSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 LSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHP 340 350 360 370 380 390 500 510 520 530 540 550 pF1KA0 DCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 DCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLI 400 410 420 430 440 450 560 570 580 590 600 610 pF1KA0 FAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 FAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQ 460 470 480 490 500 510 pF1KA0 EKD ::: CCDS76 EKD >>CCDS9164.1 DTX1 gene_id:1840|Hs108|chr12 (620 aa) initn: 2559 init1: 1130 opt: 1871 Z-score: 1315.1 bits: 253.5 E(32554): 6.3e-67 Smith-Waterman score: 2758; 64.9% identity (84.4% similar) in 610 aa overlap (7-611:25-615) 10 20 30 40 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRAGG ::::::::::.:::::. .: :::: :.. : : CCDS91 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDAR--G 10 20 30 40 50 50 60 70 80 90 100 pF1KA0 SVVLGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGSW ::::::::..:.:::::::::.::::::::.::::::.::::::::::.:::::::.:.: CCDS91 SVVLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAW 60 70 80 90 100 110 110 120 130 140 150 160 pF1KA0 TPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIYP : :::.. ::::.::::::::.::.:.:: :.: ::.:.:.::::.:.::.:::::: :: CCDS91 TAYDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYP 120 130 140 150 160 170 170 180 190 200 210 220 pF1KA0 MVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGSTGPLQLPVTRKNMP ...:..::.:::::. :.: .:::: ::.:: :..:: .. . : :.. : CCDS91 LTVGSIPKSQSWPVG---ASSG--QPCSCQQCLLVNSTRAA-----SNAI-LASQRRKAP 180 190 200 210 220 230 240 250 260 270 pF1KA0 PPGVVKLPPLPGS--GAKPLDSTGTIRGP-LKTAPSQVIRRQASSMPTGTTMGSPASPPG : . :: ::. :: . ..:. : : .::. . : : :. ::..: : CCDS91 PAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAP--PPGAPPRSPGAPGG 230 240 250 260 270 280 280 290 300 310 320 330 pF1KA0 PNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILM . :. .::: . :: . ...:. : :::..:::::::..::.:::::.::::. CCDS91 ARTP-GQ---NNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILL 290 300 310 320 330 340 340 350 360 370 380 390 pF1KA0 SAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQ :::::::::: :: .:::::::::..: .::: .. ::: ::. ::.:.::.:...:.: CCDS91 CAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQ 350 360 370 380 390 400 400 410 420 430 440 450 pF1KA0 KVRHPPDEDCTICMERLTAPSGYKGP--QPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGN ::..:::::::::::::.. :::.: . :.:.:::.:.::::.::. ::::::.::: CCDS91 KVKNPPDEDCTICMERLVTASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGN 410 420 430 440 450 460 460 470 480 490 500 510 pF1KA0 KDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHP :::::::::::.::: :::::::::::.::::::::: :: .::::.:.:: :::::::: CCDS91 KDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHP 470 480 490 500 510 520 520 530 540 550 560 570 pF1KA0 NPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVH ::::.:.:::::::::::..:::::::.::..::.:::::.::::.::::::::.:::.: CCDS91 NPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIH 530 540 550 560 570 580 580 590 600 610 pF1KA0 HKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD :::::::::::::::::.:::::::::.:::.:: CCDS91 HKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAAAKA 590 600 610 620 >>CCDS5587.1 DTX2 gene_id:113878|Hs108|chr7 (622 aa) initn: 1763 init1: 984 opt: 1316 Z-score: 929.0 bits: 182.0 E(32554): 2e-45 Smith-Waterman score: 1763; 46.9% identity (67.1% similar) in 635 aa overlap (5-617:17-622) 10 20 30 40 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEA--VVRAGPRAG-GSVV .::.:::: . : :.::: .: :: : . : : : ::.. CCDS55 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 ----LGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGS :::.: :::::::: : .::::::::.: :::. . ::::.:::::: .:.:: CCDS55 HSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 WTPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIY :: :. : ... . . .::. .:..:.....: : :. .. : :::. : CCDS55 WTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 PMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGS-TGPLQLPVTRKN :..: : : : : ::: ::. .:: :::.. :.. CCDS55 PVTTIIAP-----PGHTGVA-------CSCHQCL----------SGSRTGPVS-GRYRHS 190 200 210 230 240 250 260 270 280 pF1KA0 MPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGP : . .: : . . .: .: . :: :.: . : .. : :.::. CCDS55 MTNLPAYPVPQHPPHRTASVFGTHQAFAPYNK-PSLSGARSAPRLNTTNAWG--AAPPSL 220 230 240 250 260 270 290 300 310 320 pF1KA0 NSKT-GRVALATLNRTNLQRLAIAQSRVL--IASG-------VP-TVPVKNLNGSSPVNP .:. : .:. :. .: . ... : . :: :: :::.. . : :. CCDS55 GSQPLYRSSLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQ-MPKPSRVQQ 280 290 300 310 320 330 330 340 350 360 370 380 pF1KA0 ALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKT ::::.:..:::: ::::::.: :. . ::.:. :: .:. . ..: . : . CCDS55 ALAGMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKSHGSVKRLRKMSVKGATPKPEP 340 350 360 370 380 390 390 400 410 420 430 440 pF1KA0 -PEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKG--PQPTVKPDLVGKLSRCGHVYHI ::.:.:.: .... :::::: ::::.:.. :::. . .. ::.:..:.:..:. CCDS55 EPEQVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHL 400 410 420 430 440 450 450 460 470 480 490 500 pF1KA0 YCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYS ::.::: :::::::::::.:::::: :::::: :::: . ::::: :: :: :.:: CCDS55 LCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYS 460 470 480 490 500 510 510 520 530 540 550 560 pF1KA0 IPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTG :: :::::::::::: :.::::::.:::::. .:::::.:: ::: :::::..::::::: CCDS55 IPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTG 520 530 540 550 560 570 570 580 590 600 610 pF1KA0 ESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD :.:::.:::.:::::. :.::::::: :::.::::::::::..:: :. CCDS55 ETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 580 590 600 610 620 >>CCDS43605.1 DTX2 gene_id:113878|Hs108|chr7 (575 aa) initn: 1686 init1: 984 opt: 1153 Z-score: 816.1 bits: 161.0 E(32554): 3.9e-39 Smith-Waterman score: 1603; 44.6% identity (63.4% similar) in 623 aa overlap (5-617:17-575) 10 20 30 40 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEA--VVRAGPRAG-GSVV .::.:::: . : :.::: .: :: : . : : : ::.. CCDS43 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 ----LGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGS :::.: :::::::: : .::::::::.: :::. . ::::.:::::: .:.:: CCDS43 HSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 WTPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIY :: :. : ... . . .::. .:..:.....: : :. .. : :::. : CCDS43 WTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 PMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGS-TGPLQLPVTRKN :..: : : : : ::: ::. .:: :::.. :.. CCDS43 PVTTIIAP-----PGHTGVA-------CSCHQCL----------SGSRTGPVS-GRYRHS 190 200 210 230 240 250 260 270 280 pF1KA0 MPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGP : . .: : . . .: .: . :: :.: . : .. : :.::. CCDS43 MTNLPAYPVPQHPPHRTASVFGTHQAFAPYNK-PSLSGARSAPRLNTTNAWG--AAPPSL 220 230 240 250 260 270 290 300 310 320 330 340 pF1KA0 NSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILMS .:. : :..:..: : .: ::: .: . CCDS43 GSQP-------LYRSSLSHL-----------GPQHLP----PGSST--------SGAV-- 280 290 300 350 360 370 380 390 400 pF1KA0 AAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQK .:.:: . : : :.. .: : ... . : ::.:.:.: .. CCDS43 SASLPSGPSSSPGSVPATVPMQ------MPKPSRVQQALAGATPKPEPEPEQVIKNYTEE 310 320 330 340 350 410 420 430 440 450 pF1KA0 VRHPPDEDCTICMERLTAPSGYKG--PQPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGNK .. :::::: ::::.:.. :::. . .. ::.:..:.:..:. ::.::: :::: CCDS43 LKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCLLAMYCNGNK 360 370 380 390 400 410 460 470 480 490 500 510 pF1KA0 DGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPN :::::::.:::::: :::::: :::: . ::::: :: :: :.:::: ::::::::: CCDS43 DGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPHGIQGPEHPN 420 430 440 450 460 470 520 530 540 550 560 570 pF1KA0 PGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHH ::: :.::::::.:::::. .:::::.:: ::: :::::..::::::::.:::.:::.:: CCDS43 PGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHH 480 490 500 510 520 530 580 590 600 610 pF1KA0 KTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD :::. :.::::::: :::.::::::::::..:: :. CCDS43 KTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 540 550 560 570 >>CCDS3015.1 DTX3L gene_id:151636|Hs108|chr3 (740 aa) initn: 489 init1: 279 opt: 508 Z-score: 365.9 bits: 78.1 E(32554): 4.6e-14 Smith-Waterman score: 518; 36.7% identity (57.9% similar) in 278 aa overlap (339-609:490-739) 310 320 330 340 350 360 pF1KA0 IASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKS :. .::: :.. . ::. .:. :. CCDS30 KERKHLHQTKFADDFRKRHPNVHFVLNQESMTLTGLPNHLAKAKQYVLKGGGMSSLAGKK 460 470 480 490 500 510 370 380 390 400 410 420 pF1KA0 IPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQKVRHPPDED----CTICMERLTAPSGYKG . .: . ..: .. : :: ... :. :.:::. .. . CCDS30 LKEGHETPMDIDSDDSKAASPP---LKGSVSSEASELDKKEKGICVICMDTISNKK---- 520 530 540 550 560 570 430 440 450 460 470 480 pF1KA0 PQPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGNKDGSLQ--CPTCKTIYGVKTGTQPPGK : : .: : . :. :: : . ::::.: ::.. :.:: :. CCDS30 ----VLP-------KCKHEFCAPCI-------NKAMSYKPICPTCQTSYGIQKGNQPEGS 580 590 600 610 490 500 510 520 530 540 pF1KA0 MEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRK : . . ::::. . :: : ::. ::: ::::::: . :. : ::::...::: CCDS30 MVFTVSRDSLPGYESFGTIVITYSMKAGIQTEEHPNPGKRYP--GIQRTAYLPDNKEGRK 620 630 640 650 660 670 550 560 570 580 590 600 pF1KA0 VLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKT-EFGSNLTGHGYPDANYLDNVL ::::: :.:..:::..: : . : ::.. ::..:::: .::. .:::: .:: : CCDS30 VLKLLYRAFDQKLIFTVGYSRVLGVSDVITWNDIHHKTSRFGGPEM-YGYPDPSYLKRVK 680 690 700 710 720 730 610 pF1KA0 AELAAQGISEDSTAQEKD :: :.:: CCDS30 EELKAKGIE 740 >>CCDS41800.1 DTX3 gene_id:196403|Hs108|chr12 (347 aa) initn: 477 init1: 287 opt: 424 Z-score: 312.3 bits: 67.1 E(32554): 4.5e-11 Smith-Waterman score: 433; 32.9% identity (52.7% similar) in 292 aa overlap (358-612:67-347) 330 340 350 360 370 380 pF1KA0 NPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEI----KSIPGVSNTSRKTTKKQ :::. . . :.. :. . ..: :: CCDS41 LARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKA 40 50 60 70 80 90 390 400 410 420 430 pF1KA0 AKKGKTPEEVL------KKYLQKVRHPPDEDCTICMERLTAPSGYKG---PQPTVKPDLV ..:. . . .... :: . . : : .: : : . : : CCDS41 QRQGELMGCLALGGGGEHPEMHRAGPPPLRAAPLL------PPGARGLPPPPPPLPPPLP 100 110 120 130 140 150 440 450 460 470 pF1KA0 GKL--------SRC----GHVYHIYCLVAM---YNNGNKDGSLQ----CPTCKTIYGVKT .: : : :.. . : . .: .:: :: : .:: . CCDS41 PRLREEAEEQESTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLV 160 170 180 190 200 210 480 490 500 510 520 530 pF1KA0 GTQPP-GKMEYHLIPHS----LPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPR :.:: :.: :. .. ::.. :: : : .:::.:: :::::: . : : CCDS41 GNQPQNGRM---LVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYP--GTTR 220 230 240 250 260 540 550 560 570 580 590 pF1KA0 HCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHG :::: .: ::: :. :.:.:: :.:::: :::. ... ::..:::: .. : CCDS41 VAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFG 270 280 290 300 310 320 600 610 pF1KA0 YPDANYLDNVLAELAAQGISEDSTAQEKD ::: .:: : :: :.::..: CCDS41 YPDPTYLTRVQEELRAKGITDD 330 340 >>CCDS66410.1 DTX3 gene_id:196403|Hs108|chr12 (350 aa) initn: 477 init1: 287 opt: 424 Z-score: 312.2 bits: 67.1 E(32554): 4.5e-11 Smith-Waterman score: 433; 32.9% identity (52.7% similar) in 292 aa overlap (358-612:70-350) 330 340 350 360 370 380 pF1KA0 NPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEI----KSIPGVSNTSRKTTKKQ :::. . . :.. :. . ..: :: CCDS66 LARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKA 40 50 60 70 80 90 390 400 410 420 430 pF1KA0 AKKGKTPEEVL------KKYLQKVRHPPDEDCTICMERLTAPSGYKG---PQPTVKPDLV ..:. . . .... :: . . : : .: : : . : : CCDS66 QRQGELMGCLALGGGGEHPEMHRAGPPPLRAAPLL------PPGARGLPPPPPPLPPPLP 100 110 120 130 140 150 440 450 460 470 pF1KA0 GKL--------SRC----GHVYHIYCLVAM---YNNGNKDGSLQ----CPTCKTIYGVKT .: : : :.. . : . .: .:: :: : .:: . CCDS66 PRLREEAEEQESTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLV 160 170 180 190 200 210 480 490 500 510 520 530 pF1KA0 GTQPP-GKMEYHLIPHS----LPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPR :.:: :.: :. .. ::.. :: : : .:::.:: :::::: . : : CCDS66 GNQPQNGRM---LVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYP--GTTR 220 230 240 250 260 540 550 560 570 580 590 pF1KA0 HCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHG :::: .: ::: :. :.:.:: :.:::: :::. ... ::..:::: .. : CCDS66 VAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFG 270 280 290 300 310 320 600 610 pF1KA0 YPDANYLDNVLAELAAQGISEDSTAQEKD ::: .:: : :: :.::..: CCDS66 YPDPTYLTRVQEELRAKGITDD 330 340 350 619 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:03:34 2016 done: Wed Nov 2 20:03:35 2016 Total Scan time: 3.850 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]